WO2018127887A2 - Electrical cutting device - Google Patents

Electrical cutting device Download PDF

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Publication number
WO2018127887A2
WO2018127887A2 PCT/IB2018/052265 IB2018052265W WO2018127887A2 WO 2018127887 A2 WO2018127887 A2 WO 2018127887A2 IB 2018052265 W IB2018052265 W IB 2018052265W WO 2018127887 A2 WO2018127887 A2 WO 2018127887A2
Authority
WO
WIPO (PCT)
Prior art keywords
test tube
cut
tube rack
cotton swabs
cotton
Prior art date
Application number
PCT/IB2018/052265
Other languages
French (fr)
Other versions
WO2018127887A3 (en
Inventor
Oriana Irina BATISTA
Javier Torres
Cristian NIETO
Original Assignee
Centro Gendiagnostik
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro Gendiagnostik filed Critical Centro Gendiagnostik
Publication of WO2018127887A2 publication Critical patent/WO2018127887A2/en
Publication of WO2018127887A3 publication Critical patent/WO2018127887A3/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873Cutting or cleaving

Definitions

  • the present invention can be included in the technical field of medical and laboratory equipment, in particular for the manipulation of specimens and the preparation of tests.
  • the present invention relates to an electrical cutting device for one or more cotton swabs or other similar objects, for example objects made of plastic, soft wood or dry ice, among others.
  • the cuts are made in a sterile way, wherein the cotton swabs may contain biological samples from a human being or another organism and be used a posteriori for different applications, such as genetic testing.
  • a cotton swab is an instrument used to collect biological samples in the form of cells from different parts or organs of the body containing mucous, from which DNA is extracted to later be studied. They are also used to swab surfaces that could have biological material. They have the form of a small rod made of plastic or another material, which ends in a cotton tip, or a tip made of another similar material.
  • the present invention provides a device for cutting the tips of cotton swabs using electricity and has the advantage of allowing the cotton swabs to be cut in a sterile way and without the risk of contaminating other cells or biological samples, since the temperature of the electrical conductor it comprises, for example nichrome wire or similar, is high enough to denature any cell that remains impregnated on the surface of the conductor.
  • the temperature of the electrical conductor it comprises, for example nichrome wire or similar is high enough to denature any cell that remains impregnated on the surface of the conductor.
  • one or multiple cotton swabs which contain biological material could be cut in a sterile way and without the risk of contaminating or mixing the samples with each other, in other words, from one cotton swab to 96 or more cotton swabs contained in tubes located on a test tube rack.
  • These multiple cotton swabs will be located on the inner part of the tubes, which are arranged in a row and cut using a wire conductor (for example
  • one of the advantages is that multiple cotton swabs can be simultaneously cut in a short time.
  • the wire conductor can easily be cleaned after cutting the samples by using alcohol. Moreover, the high temperatures destroy any residue of biological material or DNA that may remain on the conductor, thereby preventing the contamination of the samples. To guarantee an even further degree of safety, the conductor could be cleaned with alcohol in a very short period of time.
  • test tube racks and test tubes could vary in size, depending on the cotton swab or material to be cut.
  • the device could also be used to cut other similar materials, for example objects made of plastic, soft wood or dry ice.
  • one aspect of the present invention relates to an electrical cutting device, characterized in that it comprises:
  • test tube rack in which to place the test tubes containing the material or object to be cut; and an adaptor to fasten the test tube rack, where the test tube rack with the adaptor is placed on the base of the cutting system.
  • the device of the invention is made up of two main parts, a test tube adaptor that contains the material to be cut and an electrical cutting system.
  • the adaptor is used to fasten the tubes with the cotton swabs to a test tube rack and prevent the same from falling after the cut.
  • Adapters of different sizes can be used depending on the amount of cotton swabs to be cut and the sizes of the test tube racks.
  • the cutting system is a system made up of two supports placed on the left and right ends and an electrical conductor wire that joins the supports. On the lower part there is a base on which the test tube rack containing the test tubes with the cotton swabs is placed, which furthermore functions as a waste collector for the cotton swabs after they are cut.
  • FIG. 1 is a perspective view of the electrical cutting device of the invention.
  • FIGs. 2A and 2B are views of multiple or one test tube rack with the adapters.
  • FIG. 3 is a front view of the platform mounted on the test tube rack with test tubes and cotton swabs to be cut.
  • FIG. 4 is a front view of the device of the invention with the test tube rack with test tubes and cotton swabs to be cut.
  • FIG. 1 shows the device which contains a conductor wire (1 ), placed between two supports (21 and 22), the function of which is to cut the cotton swabs by applying electrical current.
  • Figs. 2A and 2B contain a test tube rack (9) which consists of two hooks or adaptors (71 and 72).
  • a test tube rack (9) which consists of two hooks or adaptors (71 and 72).
  • the test tube rack (9) is attached to the lower part of the platform by the adaptors (71 and 72).
  • the small sticks of the cotton swabs pass through the holes of the test tube rack, which can contain the collector tubes or the platform that acts as a sample collector.
  • the number of openings depends on the amount of holes in the test tube rack.
  • the openings of the adaptor can be adapted to tubes with lids, without lids and arranged in rows.
  • FIG. 4 on the base (4) that functions as a support for the test tube rack (9), one can see the cotton swabs without being cut passing through the narrow openings (8) of the test tube rack. These cotton swabs are contained in tubes placed inside the test tube rack (9), which must be moved to where the conductor wire (1 ) is located to make the cut.
  • the test tube rack (9) can be moved by the base (4) of the device, which not only facilitates the movement of the test tube rack (9), but also the collection of the waste of the cut cotton swabs by means of the slot (3).

Abstract

The object of the invention relates to a device that allows objects to be cut in a sterile way, objects preferably being cotton swabs with samples from a human being or another organism, for different genetics applications or similar. The device comprises an electronic cutting system and a test tube rack in which to place the test tubes containing the material or object to be cut and an adaptor to fasten the test tube rack, 0 which is placed on the base of the cutting system.

Description

ELECTRICAL CUTTING DEVICE
OBJECT OF THE INVENTION
The present invention can be included in the technical field of medical and laboratory equipment, in particular for the manipulation of specimens and the preparation of tests.
The present invention relates to an electrical cutting device for one or more cotton swabs or other similar objects, for example objects made of plastic, soft wood or dry ice, among others. The cuts are made in a sterile way, wherein the cotton swabs may contain biological samples from a human being or another organism and be used a posteriori for different applications, such as genetic testing.
BACKGROUND OF THE INVENTION
A cotton swab is an instrument used to collect biological samples in the form of cells from different parts or organs of the body containing mucous, from which DNA is extracted to later be studied. They are also used to swab surfaces that could have biological material. They have the form of a small rod made of plastic or another material, which ends in a cotton tip, or a tip made of another similar material.
Several different applications in genetic research or testing require the use of a cotton swab for collecting biological samples from any organism being studied. Furthermore, some applications require the use of more than one cotton swab with a biological sample in order to obtain a sufficient amount of DNA. In addition, the existence of multiple cotton swabs is recommendable and valuable given the need for replacement samples due to involuntary mistakes or equipment failure, the confirmation of the results and/or external controls in reference laboratories, among others.
All of these requirements for biological material in cotton swabs result in the accumulation of multiple cotton swabs in the laboratory, which must be processed to extract DNA contained in the cells impregnated on the tip or end part of the cotton swab. To initiate this process, it is necessary to detach the end part of the cotton swab which contains the biological material (that is, the tip of the swab) from the rest of the small stick in order to place it in a tube, which will allow the DNA extraction to begin using the combination of suitable reagents.
In many laboratories, current solutions are designed to individually cut the cotton swabs, in the majority of the cases using pliers or similar tools. In other laboratories, cotton swabs with detachable tips are used, which can be added to the tubes after the samples are taken.
Both procedures lack in efficiency, since adding the tips of cotton swabs to the collection tube is done individually, and therefore requires more time. The use of pliers or similar tools is not practical, since after cutting the cotton it is necessary to clean the pliers with a paper towel or another material impregnated with alcohol in order to remove possible remains of cells adhered to the tool. In a similar way, the use of fire with lighters or other devices to individually decontaminate the pliers is a slow procedure. In addition to this, the use of cotton swabs with detachable tips could involve higher costs, and could also lead to a risk of mixing the samples if the separation of the cotton swab tip is done outside the laboratory and not by a professional.
Furthermore, although there are other devices that use electricity, the majority of them are based on the use of blades or similar tools placed at the end of a device, as can be seen in the patent application US20100198220A1 . These devices, as manufactured, with one free end and without additional adapters to fasten the cotton swabs, would not be very effective for cutting multiple cotton swabs, since they could cause the same to fall by sliding over a group of them, which could also cause the samples to be mixed.
Therefore, in this field it is necessary to search for new alternatives for cutting several objects in a simultaneous and simple way and which, at the same time, is sterile and does not lead to a contamination of the samples.
DESCRIPTION OF THE INVENTION
The present invention provides a device for cutting the tips of cotton swabs using electricity and has the advantage of allowing the cotton swabs to be cut in a sterile way and without the risk of contaminating other cells or biological samples, since the temperature of the electrical conductor it comprises, for example nichrome wire or similar, is high enough to denature any cell that remains impregnated on the surface of the conductor. This way, one or multiple cotton swabs which contain biological material could be cut in a sterile way and without the risk of contaminating or mixing the samples with each other, in other words, from one cotton swab to 96 or more cotton swabs contained in tubes located on a test tube rack. These multiple cotton swabs will be located on the inner part of the tubes, which are arranged in a row and cut using a wire conductor (for example, nichrome wire or similar) through which electrical current circulates.
Therefore, one of the advantages is that multiple cotton swabs can be simultaneously cut in a short time.
The wire conductor can easily be cleaned after cutting the samples by using alcohol. Moreover, the high temperatures destroy any residue of biological material or DNA that may remain on the conductor, thereby preventing the contamination of the samples. To guarantee an even further degree of safety, the conductor could be cleaned with alcohol in a very short period of time.
The test tube racks and test tubes could vary in size, depending on the cotton swab or material to be cut.
The device could also be used to cut other similar materials, for example objects made of plastic, soft wood or dry ice.
Therefore, one aspect of the present invention relates to an electrical cutting device, characterized in that it comprises:
- an electronic cutting system that comprises
o a wire that conducts electrical current located on the upper part between two supports and a base on the lower part of the two supports; and
- a test tube rack in which to place the test tubes containing the material or object to be cut; and an adaptor to fasten the test tube rack, where the test tube rack with the adaptor is placed on the base of the cutting system.
The device of the invention is made up of two main parts, a test tube adaptor that contains the material to be cut and an electrical cutting system. The adaptor is used to fasten the tubes with the cotton swabs to a test tube rack and prevent the same from falling after the cut. Adapters of different sizes can be used depending on the amount of cotton swabs to be cut and the sizes of the test tube racks. The cutting system, as such, is a system made up of two supports placed on the left and right ends and an electrical conductor wire that joins the supports. On the lower part there is a base on which the test tube rack containing the test tubes with the cotton swabs is placed, which furthermore functions as a waste collector for the cotton swabs after they are cut.
On the left-hand support of the cutter there is an opening or slit where the waste collector is inserted. On the lower part of the right support there is an electrical device. DESCRIPTION OF THE DRAWINGS FIG. 1 is a perspective view of the electrical cutting device of the invention.
FIGs. 2A and 2B are views of multiple or one test tube rack with the adapters.
FIG. 3 is a front view of the platform mounted on the test tube rack with test tubes and cotton swabs to be cut.
FIG. 4 is a front view of the device of the invention with the test tube rack with test tubes and cotton swabs to be cut.
PREFERRED EMBODIMENT OF THE INVENTION
A detailed description of a preferred exemplary embodiment of the device of the present invention is provided below.
FIG. 1 shows the device which contains a conductor wire (1 ), placed between two supports (21 and 22), the function of which is to cut the cotton swabs by applying electrical current. On the right-hand support (21 ) there is an electrical cord (6) which must be connected to a switch and which provides enough electrical current to the conductor to cut the cotton swabs. It further contains a base (4) and a waste collector which is embedded in the slot (3) of the left-hand support (22).
Figs. 2A and 2B contain a test tube rack (9) which consists of two hooks or adaptors (71 and 72). On the middle part of the test tube rack there are small openings (8) that reduce the size of the opening of the collector tubes for the tips of the cotton swabs and guarantee that the cotton swabs do not fall outside the same after being cut, due to the fact that the same are smaller than the tip which is in the lower part of the tube, as can be seen in FIG. 3. The test tube rack (9) is attached to the lower part of the platform by the adaptors (71 and 72). The small sticks of the cotton swabs pass through the holes of the test tube rack, which can contain the collector tubes or the platform that acts as a sample collector. The number of openings depends on the amount of holes in the test tube rack. The openings of the adaptor can be adapted to tubes with lids, without lids and arranged in rows.
In FIG. 4, on the base (4) that functions as a support for the test tube rack (9), one can see the cotton swabs without being cut passing through the narrow openings (8) of the test tube rack. These cotton swabs are contained in tubes placed inside the test tube rack (9), which must be moved to where the conductor wire (1 ) is located to make the cut. The test tube rack (9) can be moved by the base (4) of the device, which not only facilitates the movement of the test tube rack (9), but also the collection of the waste of the cut cotton swabs by means of the slot (3).

Claims

1 . An electrical cutting device characterized in that it comprises:
- an electronic cutting system that comprises
o a wire that conducts electrical current located on the upper part between two supports and a base on the lower part of the two supports; and
- a test tube rack in which to place the test tubes containing the material to be cut; and an adaptor to fasten the test tube rack, wherein the test tube rack with the adaptor is placed on the base of the cutting system.
2. The device according to claim 1 , wherein the wire is a nichrome wire.
3. The device according to claim 1 , wherein the material to be cut is a cotton swab.
PCT/IB2018/052265 2018-03-14 2018-04-02 Electrical cutting device WO2018127887A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PA92041 2018-03-14
PA9204101 2018-03-14

Publications (2)

Publication Number Publication Date
WO2018127887A2 true WO2018127887A2 (en) 2018-07-12
WO2018127887A3 WO2018127887A3 (en) 2018-09-20

Family

ID=62790783

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2018/052265 WO2018127887A2 (en) 2018-03-14 2018-04-02 Electrical cutting device

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114522752A (en) * 2022-02-21 2022-05-24 南昌大学第一附属医院 Test tube rack for nucleic acid detection and sample collection
DE102021208425A1 (en) 2021-08-04 2023-02-09 Robert Bosch Gesellschaft mit beschränkter Haftung Process and device for the production of lab-on-chip cartridges

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2987598A (en) * 1958-05-09 1961-06-06 Howard E Chace Devices for severing plastic material
US4300423A (en) * 1978-11-08 1981-11-17 Paul Price Apparatus for severing and separating cup-shaped object supports
US5762873A (en) * 1996-02-21 1998-06-09 Biomerieux Vitek, Inc. Automatic sample testing machine
SE539954C2 (en) * 2014-07-08 2018-02-13 Grade Group As Cutting device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102021208425A1 (en) 2021-08-04 2023-02-09 Robert Bosch Gesellschaft mit beschränkter Haftung Process and device for the production of lab-on-chip cartridges
CN114522752A (en) * 2022-02-21 2022-05-24 南昌大学第一附属医院 Test tube rack for nucleic acid detection and sample collection

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Publication number Publication date
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