WO2018099912A1 - Trousse de départ pour titrage de taux de base - Google Patents

Trousse de départ pour titrage de taux de base Download PDF

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Publication number
WO2018099912A1
WO2018099912A1 PCT/EP2017/080682 EP2017080682W WO2018099912A1 WO 2018099912 A1 WO2018099912 A1 WO 2018099912A1 EP 2017080682 W EP2017080682 W EP 2017080682W WO 2018099912 A1 WO2018099912 A1 WO 2018099912A1
Authority
WO
WIPO (PCT)
Prior art keywords
subject
insulin
insulin medicament
dataset
time course
Prior art date
Application number
PCT/EP2017/080682
Other languages
English (en)
Inventor
Brad VAN ORDEN
ARADÓTTIR Tinna BJÖRK
Henrik Bengtsson
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Priority to CN201780073916.1A priority Critical patent/CN110012675B/zh
Priority to JP2019528702A priority patent/JP7195254B2/ja
Priority to EP17823040.5A priority patent/EP3549133A1/fr
Priority to US16/461,059 priority patent/US11195607B2/en
Publication of WO2018099912A1 publication Critical patent/WO2018099912A1/fr

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Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
    • G16H20/17—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • General Health & Medical Sciences (AREA)
  • Databases & Information Systems (AREA)
  • Pathology (AREA)
  • Data Mining & Analysis (AREA)
  • Business, Economics & Management (AREA)
  • General Business, Economics & Management (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention porte sur des systèmes et des méthodes de traitement d'un sujet. Un premier ensemble de données comprenant des mesures de glucose autonomes horodatées du sujet sur un premier laps de temps est obtenu. Un second ensemble de données, associé à un régime d'insuline constant pour le sujet sur le premier laps de temps et comprenant des enregistrements de médicament à base d'insuline est également obtenu. Chaque enregistrement comprend un événement d'administration horodaté comprenant une quantité et un type de médicament à base d'insuline administré au sujet par un dispositif d'administration d'insuline. Les premier et second ensembles de données servent à calculer une mesure de risque glycémique et un facteur de sensibilité à l'insuline du sujet pendant le premier laps de temps, lesquels sont utilisés pour obtenir un programme de titrage de taux de base et un modèle de profil de glycémie à jeun sur un second laps de temps ultérieur pour le sujet. Le modèle prédit le taux de glycémie à jeun du sujet en fonction des quantités de médicament à base d'insuline administrées au sujet.
PCT/EP2017/080682 2016-11-29 2017-11-28 Trousse de départ pour titrage de taux de base WO2018099912A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CN201780073916.1A CN110012675B (zh) 2016-11-29 2017-11-28 用于基础率滴定的起始套件
JP2019528702A JP7195254B2 (ja) 2016-11-29 2017-11-28 基礎速度滴定のためのスターターキット
EP17823040.5A EP3549133A1 (fr) 2016-11-29 2017-11-28 Trousse de départ pour titrage de taux de base
US16/461,059 US11195607B2 (en) 2016-11-29 2017-11-28 Starter kit for basal rate titration

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201662427333P 2016-11-29 2016-11-29
US62/427333 2016-11-29
EP17151561.2 2017-01-16
EP17151561 2017-01-16

Publications (1)

Publication Number Publication Date
WO2018099912A1 true WO2018099912A1 (fr) 2018-06-07

Family

ID=57821845

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2017/080682 WO2018099912A1 (fr) 2016-11-29 2017-11-28 Trousse de départ pour titrage de taux de base

Country Status (1)

Country Link
WO (1) WO2018099912A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112567470A (zh) * 2018-08-28 2021-03-26 诺和诺德股份有限公司 用于提供基于药物剂量指导的容器以治疗糖尿病的系统和方法
WO2021072437A1 (fr) * 2019-10-11 2021-04-15 Bigfoot Biomedical, Inc. Ajustement du réglage d'une thérapie à l'insuline sur la base de la variabilité des valeurs de glycémie

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009075925A1 (fr) 2007-12-13 2009-06-18 Shaya Steven A Procédé et appareil destinés à calculer les facteurs de sensibilité intervenant dans la glycémie chez les diabétiques
US20120089893A1 (en) 2008-12-23 2012-04-12 Roche Diagnostics Operations, Inc. Management Method And System For Implementation, Execution, Data Collection, and Data Analysis Of A Structured Collection Procedure Which Runs On A Collection Device
US20140107607A1 (en) * 2012-10-16 2014-04-17 Asante Solutions, Inc. Infusion Pump System and Methods

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009075925A1 (fr) 2007-12-13 2009-06-18 Shaya Steven A Procédé et appareil destinés à calculer les facteurs de sensibilité intervenant dans la glycémie chez les diabétiques
US20120089893A1 (en) 2008-12-23 2012-04-12 Roche Diagnostics Operations, Inc. Management Method And System For Implementation, Execution, Data Collection, and Data Analysis Of A Structured Collection Procedure Which Runs On A Collection Device
US20140107607A1 (en) * 2012-10-16 2014-04-17 Asante Solutions, Inc. Infusion Pump System and Methods

Non-Patent Citations (14)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "Cluster analysis - Wikipedia", 13 November 2016 (2016-11-13), XP055454723, Retrieved from the Internet <URL:https://en.wikipedia.org/w/index.php?title=Cluster_analysis&oldid=749256561> [retrieved on 20180227] *
ANONYMOUS: "Learning classifier system - Wikipedia", 28 November 2016 (2016-11-28), XP055454719, Retrieved from the Internet <URL:https://en.wikipedia.org/w/index.php?title=Learning_classifier_system&oldid=751858603> [retrieved on 20180227] *
BACKER: "Computer-Assisted Reasoning in Cluster Analysis", 1995, PRENTICE HALL
BLONDE ET AL.: "Patient-directed titration for achieving glycaemic goals using a once-daily basal insulin analogue: an assessment of two different fasting plasma glucose targets - the TITRATETM study", DIABETES, OBESITY AND METABOLISM, vol. 11, 2009, pages 623 - 631
DUDA ET AL.: "Pattern Classification", JOHN WILEY & SONS, INC., pages: 537 - 563
DUDA; HART: "Pattern Classification and Scene Analysis", 1973, JOHN WILEY & SONS, INC., pages: 211 - 256
DUNN ET AL.: "An Updated Review of its Use in the Management of Diabetes Mellitus", DRUGS, vol. 63, 2003, pages 1743
EVERITT: "Cluster analysis", 1993, WILEY
GERICH: "Novel insulins: expanding options in diabetes management", AM J MED., vol. 113, 2002, pages 308 - 316, XP085014826, DOI: doi:10.1016/S0002-9343(02)01176-2
GLARGINE, LANTUS, 2 March 2007 (2007-03-02)
HELMS KELLEY: "Insulin glulisine: an evaluation of its pharmacodynamic properties and clinical application", ANN PHARMACOTHER, vol. 43, 2009, pages 658 - 668
KAUFMAN; ROUSSEEUW: "Finding Groups in Data: An Introduction to Cluster Analysis", 1990, WILEY
PLANK ET AL.: "A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of the long-acting insulin analog detemir", DIABETES CARE, vol. 28, 2005, pages 1107 - 1112
SCHMID: "New options in insulin therapy", J PEDIATRIA (RIO J, vol. 83, no. 5, 2007, pages S146 - S155

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112567470A (zh) * 2018-08-28 2021-03-26 诺和诺德股份有限公司 用于提供基于药物剂量指导的容器以治疗糖尿病的系统和方法
WO2021072437A1 (fr) * 2019-10-11 2021-04-15 Bigfoot Biomedical, Inc. Ajustement du réglage d'une thérapie à l'insuline sur la base de la variabilité des valeurs de glycémie

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