WO2018062984A3 - New method for synthesising dendron-based chromatography resins - Google Patents

New method for synthesising dendron-based chromatography resins Download PDF

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Publication number
WO2018062984A3
WO2018062984A3 PCT/MX2017/000109 MX2017000109W WO2018062984A3 WO 2018062984 A3 WO2018062984 A3 WO 2018062984A3 MX 2017000109 W MX2017000109 W MX 2017000109W WO 2018062984 A3 WO2018062984 A3 WO 2018062984A3
Authority
WO
WIPO (PCT)
Prior art keywords
chromatography
dendron
synthesising
chromatography resins
new method
Prior art date
Application number
PCT/MX2017/000109
Other languages
Spanish (es)
French (fr)
Other versions
WO2018062984A2 (en
Inventor
Marco Arnulfo MATA GÓMEZ
José Guillermo GONZÁLEZ VALDEZ
Jesús Ángel VALENCIA GALLEGOS
Marco Antonio Rito Palomares
Original Assignee
Instituto Tecnológico y de Estudios Superiores de Monterrey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Instituto Tecnológico y de Estudios Superiores de Monterrey filed Critical Instituto Tecnológico y de Estudios Superiores de Monterrey
Publication of WO2018062984A2 publication Critical patent/WO2018062984A2/en
Publication of WO2018062984A3 publication Critical patent/WO2018062984A3/en

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/02—Polyesters derived from dicarboxylic acids and dihydroxy compounds
    • C08L67/03—Polyesters derived from dicarboxylic acids and dihydroxy compounds the dicarboxylic acids and dihydroxy compounds having the carboxyl- and the hydroxy groups directly linked to aromatic rings

Abstract

The present invention relates to an improved method for the synthesis of dendron-based chromatography resins. The method comprises incorporating dendrons, molecules having a branched structure, into the chromatography resin. In a second step, the functional groups of the dendron are functionalised with ligands. The method can be applied to a wide variety of materials of different natures for the synthesis of chromatography resins for a wide variety of chromatography processes such as hydrophobic interaction chromatography (HIC), ion-exchange chromatography (IEXC), reversed-phase chromatography (RPC) and affinity chromatography (AC), inter alia.
PCT/MX2017/000109 2016-09-28 2017-09-27 New method for synthesising dendron-based chromatography resins WO2018062984A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
MXMX/A/2016/012737 2016-09-28
MX2016012737A MX2016012737A (en) 2016-09-28 2016-09-28 A novel method for synthesizing chromatographic resins based on dendrons.

Publications (2)

Publication Number Publication Date
WO2018062984A2 WO2018062984A2 (en) 2018-04-05
WO2018062984A3 true WO2018062984A3 (en) 2018-08-23

Family

ID=61759857

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/MX2017/000109 WO2018062984A2 (en) 2016-09-28 2017-09-27 New method for synthesising dendron-based chromatography resins

Country Status (2)

Country Link
MX (1) MX2016012737A (en)
WO (1) WO2018062984A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616568A (en) * 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
US20130184429A1 (en) * 2010-07-28 2013-07-18 The University Of Akron Functional biodegradable polymers
US8598308B2 (en) * 2007-10-24 2013-12-03 Instituto Tecnológico y de Estudios Superiores de Monterrey Multifunctional dendrons and dendrimers with a high loading capacity

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5616568A (en) * 1993-11-30 1997-04-01 The Research Foundation Of State University Of New York Functionalized derivatives of hyaluronic acid
US8598308B2 (en) * 2007-10-24 2013-12-03 Instituto Tecnológico y de Estudios Superiores de Monterrey Multifunctional dendrons and dendrimers with a high loading capacity
US20130184429A1 (en) * 2010-07-28 2013-07-18 The University Of Akron Functional biodegradable polymers

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GOMEZ ET AL.: "Synthesis of adsorbents with dendronic structures for proteinhydrophobic interaction chromatography", JOURNAL OF CHROMATOGRAPHY A, vol. 1443, 2016, pages 191 - 200, XP029491240 *

Also Published As

Publication number Publication date
MX2016012737A (en) 2018-03-27
WO2018062984A2 (en) 2018-04-05

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