WO2018051071A9 - Detection and treatment of microsporidian infection - Google Patents

Detection and treatment of microsporidian infection Download PDF

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Publication number
WO2018051071A9
WO2018051071A9 PCT/GB2017/052676 GB2017052676W WO2018051071A9 WO 2018051071 A9 WO2018051071 A9 WO 2018051071A9 GB 2017052676 W GB2017052676 W GB 2017052676W WO 2018051071 A9 WO2018051071 A9 WO 2018051071A9
Authority
WO
WIPO (PCT)
Prior art keywords
infection
treatment
microsporidian
nucleic acid
isolated
Prior art date
Application number
PCT/GB2017/052676
Other languages
French (fr)
Other versions
WO2018051071A1 (en
Inventor
Felix Scholz
Hamish RODGER
Original Assignee
Benchmark Animal Health Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Benchmark Animal Health Limited filed Critical Benchmark Animal Health Limited
Publication of WO2018051071A1 publication Critical patent/WO2018051071A1/en
Publication of WO2018051071A9 publication Critical patent/WO2018051071A9/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56961—Plant cells or fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Botany (AREA)
  • Hematology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Virology (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

An isolated or synthetic nucleic acid from having a sequence selected from the group consisting of SEQ ID NOs: 9, 13 and 1-8, or a homologues thereof, an isolated or synthetic nucleic acid complementary to a sequence selected from the group consisting of SEQ ID NOs: 1-14, or a homologues thereof, an isolated polypeptide encoded by the nucleic acid, or an antibody that binds thereto, may be used as an immunogenic composition or diagnostic, or in a method of treatment or prevention, in respect of a microsporidian infection, in particular a Tetramicra brevifilum infection in animals, particularly fish. Additionally, methods of testing an agent for the prevention and/or treatment of a microsporidian infection, preferably a Tetramicra brevifilum infection, and kits for screening for a microsporidian infection, are provided.
PCT/GB2017/052676 2016-09-13 2017-09-12 Detection and treatment of microsporidian infection WO2018051071A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1615550.9 2016-09-13
GBGB1615550.9A GB201615550D0 (en) 2016-09-13 2016-09-13 Detection and treatment of microsporidian infection

Publications (2)

Publication Number Publication Date
WO2018051071A1 WO2018051071A1 (en) 2018-03-22
WO2018051071A9 true WO2018051071A9 (en) 2018-04-19

Family

ID=57234525

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2017/052676 WO2018051071A1 (en) 2016-09-13 2017-09-12 Detection and treatment of microsporidian infection

Country Status (2)

Country Link
GB (1) GB201615550D0 (en)
WO (1) WO2018051071A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111020050B (en) * 2020-01-13 2022-09-13 宁波大学 Primer and probe sequence for LAMP-LFD detection of plecoglossus altivelis

Also Published As

Publication number Publication date
WO2018051071A1 (en) 2018-03-22
GB201615550D0 (en) 2016-10-26

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