WO2018042218A1 - Filtering ocular device and method using such a device - Google Patents

Filtering ocular device and method using such a device Download PDF

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Publication number
WO2018042218A1
WO2018042218A1 PCT/IB2016/055139 IB2016055139W WO2018042218A1 WO 2018042218 A1 WO2018042218 A1 WO 2018042218A1 IB 2016055139 W IB2016055139 W IB 2016055139W WO 2018042218 A1 WO2018042218 A1 WO 2018042218A1
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WIPO (PCT)
Prior art keywords
filtration
wavelengths
transmission
frequency
duration
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PCT/IB2016/055139
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French (fr)
Inventor
Eugène DUVILLARD
Original Assignee
Duvillard Eugene
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Duvillard Eugene filed Critical Duvillard Eugene
Priority to PCT/IB2016/055139 priority Critical patent/WO2018042218A1/en
Publication of WO2018042218A1 publication Critical patent/WO2018042218A1/en

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    • GPHYSICS
    • G02OPTICS
    • G02CSPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00Optical parts
    • G02C7/10Filters, e.g. for facilitating adaptation of the eyes to the dark; Sunglasses
    • G02C7/104Filters, e.g. for facilitating adaptation of the eyes to the dark; Sunglasses having spectral characteristics for purposes other than sun-protection
    • GPHYSICS
    • G02OPTICS
    • G02CSPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C2202/00Generic optical aspects applicable to one or more of the subgroups of G02C7/00
    • G02C2202/24Myopia progression prevention

Definitions

  • the present invention relates to an ocular device for selective filtration of a wavelength or a range of wavelengths.
  • the invention also includes a method for regulating the life cycle by filtering a wavelength or range of wavelengths.
  • An object of the present invention is to remedy malfunctions due to the exposure of the retina to certain wavelengths, in particular those between 400 and 560 nm.
  • the present invention therefore includes an ocular device for filtering a certain category of wavelengths.
  • the ocular device comprises a filtration surface, also called filtering surface, which can be flat or curved, which is disposed between the retina and the light source, so as to specifically limit the exposure to this category of wavelengths.
  • the filtration surface of the ocular device is preferably tinted a yellow / orange color.
  • the material used for the filtration surface may be selected from materials commonly used for optical devices, such as glass, a rigid polymer such as polycarbonate, a flexible polymer, a silicone derivative, and a rigid or deformable plastic.
  • the filtration surface may have a homogeneous or variable thickness, and may additionally or alternatively have a given refractive index, or have several refractive indices at different locations on the surface.
  • a second object of the invention is a method for rectifying or restoring the production cycles of melatonin and / or other organic compounds regulated by brightness, or aimed at preventing drifts of the circadian cycle.
  • Dopamine is one of the substances whose production is regulated by light exposure.
  • a method according to the present invention may be curative or preventive.
  • the object of the present invention is to remedy malfunctions due to the exposure of the retina to certain wavelengths, in particular those between 400 and 560 nm.
  • a second aspect is to correct the malfunctions due to the exposure of the retina to certain wavelengths, in particular those between 400 and 560 nm.
  • a third aspect of the invention is to prevent malfunctions due to the exposure of the retina to certain wavelengths, in particular those between 400 and 560 nm.
  • an ocular device for filtering a certain category of wavelengths is the subject of the invention.
  • the ocular device comprises a filtration surface, or a filtering surface, which may be flat or curved, which is disposed between the retina and the light source, so as to specifically limit the exposure to this category of wavelengths.
  • a wavelength category here denotes a set of wavelengths spread over a range or several ranges of given wavelengths.
  • the filtered wavelengths are preferably between 400 and 560 nm, more preferably between 460 and 520 nm.
  • the most advantageously filtered wavelength range is between 470 and 490 nm.
  • the wavelengths are filtered so as to limit their transmission slightly, that is to say to limit their transmission by a value between 5% and approximately 60% or between 5% and 60%. % and 80%, but preferably between 10% and 50%, and even more advantageously between 15% and 30%.
  • the wavelengths are filtered so as to significantly limit their transmission, that is to say to limit their transmission by a value between 80% and 98%, or between 85% and 95%.
  • the wavelengths are filtered so as to totally or substantially limit their transmission, that is to say to limit their transmission by a value greater than 98%.
  • a narrow spectrum of wavelength is totally filtered.
  • a restricted wavelength range of from about 470 to about 490 nm is filtered to completely or substantially limit their transmission.
  • the invention makes it possible to filter a range of wavelengths between about 470 and about 490 nm so as to limit their transmission by a value greater than 98%.
  • a wide range of wavelengths is filtered weakly or significantly.
  • a wavelength range between about 400 or 420 nm, and about 580 nm is filtered so as to limit the transmission by a value between 5% and 60%, or between about 10% and about 50%, or from about 15% to about 30%, or from about 80% to 98%.
  • the value of the lowering of the transmission can be homogeneous over the whole wavelength range considered, or vary within the limits of the range within this range, between 5% and 60%, between 10% and 50%, or between 15% and 30%, or between 80% and 98%.
  • a restricted range of wavelength length is completely filtered or substantially completely filtered, and an extended range of wavelength is weakly or significantly filtered.
  • the device according to the invention can be optimized to filter a range of wavelengths between 470 and 490 nm so as to limit their transmission by a value greater than 98%, and to filter the lengths of waves outside this range and between 420 and 580 nm so as to limit their transmission by a value between about 5% and about 60%, or a value between about 10% and about 50%, or between about 15% and 30%, or between 80% and 98%.
  • the transmission of wavelengths between 470 and 490 nm is limited to a value between 70% and 80%, and the transmission of the other wavelengths, provided that they are between 420 and 580 nm is limited to a value between 15% and -30%.
  • limit transmission should be understood as “lower transmission” or “mitigate transmission”.
  • the value of the limitation is in reference to a total transmission of 100%.
  • limiting the transmission by a value of 70% means that 30% of the wavelength considered is transmitted through the device of the present invention.
  • the ocular device can take any suitable form such as a pair of spectacles, eye lenses or a panoramic visor.
  • the ocular device is preferably positioned or positionable in front of the user's eyes, or directly on the retina. In a particular mode of operation, it is envisaged that the device may be grafted into the cornea or under the cornea.
  • the ocular device may alternatively take the form of a screen, which is available in front of the light source and remote from the user. Such a screen can for example be fixed directly on the light source.
  • the filtration surface may be a film that is available on another surface, such as a computer screen or TV, or on a window.
  • the film can be flexible and adhere to another surface through electrostatic interactions.
  • the film may be more rigid so that it can be held in contact with another surface.
  • the film can alternatively be glued to another surface.
  • the device may take the form of a window, such as a vehicle or dwelling window, or any other positionable surface at a variable distance from the light source to protect one or more users.
  • the filtration surface of the ocular device can therefore take all dimensions and have a variable thickness.
  • the thickness of the filtration surface is preferably between 0.1 mm and more than 1 cm, preferably between 0.3 mm and 0.8 mm.
  • the filtration surface may have a homogeneous or variable thickness. The thickness may in particular be greater on the central part than on the edges, or less important.
  • the variation in thickness of the filtration surface may be progressive or non-progressive.
  • the filtration surface may for example take the form of a spectacle lens with a thickness of between 0.2 and 0.4 mm on its peripheral part, and a thickness of between 0.4 and 0.6 mm on its part. central, and where the thickness variation between its peripheral portion and its central portion is progressive.
  • the relief of the filtration surface may be adaptable to particular uses, in particular for optical corrections of any kind.
  • the filtration surface may additionally or alternatively have a given refractive index, or have several refractive indices at different locations on the surface. This includes any gradient of reflection indexes.
  • the filtration surface of the present invention may have the advantage of an optical defect correction such as presbyopia, myopia, hyperopia, astigmatism, in combination with the selective filtration of certain wavelengths .
  • the device according to the invention can be used in combination with another optical device such as eyeglasses, or contact lenses.
  • the filtration surface of the ocular device is preferably tinted a yellow / orange color.
  • the coloration of the filtering surface makes it possible in this case to limit glare from artificial light sources, in particular in a nocturnal environment, where the contrast between the light source and the environment is increased. This is particularly the case when the use of a light device, such as a computer or a mobile phone, in a dark room.
  • the coloring is preferably included in the material of the filtering surface, so as to limit its sensitivity to wear and scratches.
  • the material used for the filtration surface may be selected from materials commonly used for optical devices.
  • the filtration surface may in particular be made of glass, a rigid polymer such as polycarbonate, a flexible polymer, a silicone derivative, a rigid or deformable plastic.
  • the filtration surface may alternatively consist of several materials selected from glass, a rigid polymer such as polycarbonate, a flexible polymer, a silicone derivative, a rigid or deformable plastic.
  • the materials composing the filtration surface may be juxtaposed, so as to confer variable properties depending on the considered location of the filtration surface.
  • the filtration surface may have a rigid central portion, and a flexible peripheral portion, or vice versa.
  • the materials composing the filtration surface can be superimposed in successive layers.
  • the filtration surface can then contain several layers, where at least one of these layers of materials can selectively filter the wavelengths concerned.
  • the device may have a plurality of filtration surfaces, one of which is placed between the light source and the retina.
  • the additional filtering surface (s) may be arranged laterally, so as to filter the indirect or residual light emissions or in the case of several light emissions.
  • a second object of the present invention is a curative method for rectifying or restoring the cycles of production of melatonin and / or other organic compounds regulated by exposure to light.
  • a curative method according to the present invention comprises in particular the sequential port of the ocular filtration device for a predetermined duration, and at a predetermined frequency.
  • the predetermined duration can be constant throughout the period of use, or variable between the beginning and the end of the period of sequential use. It can be for example between 15 minutes and 5 hours.
  • the frequency of use can also be regular or variable. A regular frequency may for example be 24, or 48 hours. A variable frequency may for example be between 24 hours and 72 hours, between the start of use and the end of use.
  • the curative method according to the present invention may further comprise several phases, each phase of use having a duration and a natural frequency.
  • An exemplary curative method comprises a first phase of use where the duration and the frequency of use are constant, a second phase of use where one or the other of the duration and the frequency varies gradually , and a third phase of use where frequency and duration of use are again constant.
  • the curative use of the ocular filtration device according to the method of the present invention may for example be the following: - A first phase of use, where the user wears the filtration device for three hours each evening two hours before bedtime, for a week,
  • a second phase of use where the user wears the filter device for a period that decreases by a given value every third night.
  • the value of the decrease can be half an hour, or a time, or any intermediate value.
  • the user will wear the device for 2h30 three nights in a row two hours before the usual bedtime, then for 2h the following three nights, up to a given limit of duration of use, which may be for example d 'one o'clock.
  • a final phase of use where the user wears the ocular filtration device for one hour, at a constant frequency of 48 hours, for a week.
  • the curative method according to the present invention can for example be applied for chronic sleep disorders, or for a better recovery of the circadian rhythm after a long trip causing a jet lag.
  • the method according to the present invention can also be used for preventive purposes.
  • the user can in this case wear the device at a fixed time each day, or during exposure to harmful wavelengths.
  • the method according to the invention can be used to regulate metabolisms directly or indirectly related to the production or inhibition of melatonin.
  • the present method thus makes it possible to lower the heart rate and / or the body temperature.
  • the method according to the invention can be used to regulate metabolisms directly or indirectly related to the production or inhibition of dopamine.
  • the use of the filtering eye device according to a method of the invention thus makes it possible to influence the evolution of myopia, and in particular to slow the evolution of myopia.
  • the use of the ocular filtration device according to a method of the invention also makes it possible to influence the evolution of astigmatism, and in particular to slow down the evolution of astigmatism.
  • the ocular filtration device can be used during nocturnal periods or diurnal periods, or a combination of both.

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Eyeglasses (AREA)

Abstract

The invention relates to a filtering ocular device comprising a light filtering surface which allows attenuation of the transmission of a range of wavelengths between 400 and 580 nm. The device is advantageously tinted with a yellow/orange colour.

Description

Dispositif oculaire de filtration et méthode utilisant un tel dispositif  Ocular filtration device and method using such a device
Domaine technique Technical area
La présente invention est relative à un dispositif oculaire de filtration sélective d'une longueur d'onde ou d'une plage de longueurs d'ondes. L'invention comprend également une méthode visant à réguler le cycle biologique grâce à la filtration d'une longueur d'onde ou d'une plage de longueurs d'ondes. The present invention relates to an ocular device for selective filtration of a wavelength or a range of wavelengths. The invention also includes a method for regulating the life cycle by filtering a wavelength or range of wavelengths.
Etat de la technique L'exposition à la lumière artificielle en période nocturne, et notamment à celle émise par les ampoules basse consommation, les écrans d'ordinateurs, de consoles, de tablettes, ou de téléphones portables, conduit à des dérèglements biologiques. Les dérèglements liés à la production de mélatonine sont parmi les plus fréquemment mentionnés. La mélatonine permet notamment de réguler les cycles de sommeil. La production de mélatonine est directement liée à l'exposition ou la non-exposition de la rétine à certaines longueurs d'ondes lumineuses, et se trouve perturbée lors de l'utilisation de certains dispositifs lumineux pendant les heures nocturnes. Il en résulte des difficultés d'endormissement, des perturbations du sommeil, voir des dérèglements du métabolisme. Devant la généralisation de l'utilisation des appareils lumineux durant les périodes nocturnes, il apparaît nécessaire de remédier à ces dérèglements. Les demandes de brevet US 2014277292 et WO2015123690 relatent de dispositifs similaires de filtration optique. STATE OF THE ART Exposure to artificial light during the night, and in particular to that emitted by low energy light bulbs, computer screens, consoles, tablets, or mobile phones, leads to biological disturbances. Disorders related to the production of melatonin are among the most frequently mentioned. Melatonin helps to regulate sleep cycles. The production of melatonin is directly related to the exposure or non-exposure of the retina to certain wavelengths of light, and is disturbed when using certain light devices during the night hours. This results in difficulties of falling asleep, disturbances of sleep, see disturbances of metabolism. In front of the generalization of the use of luminous devices during the nocturnal periods, it appears necessary to remedy these disturbances. Patent applications US 2014277292 and WO2015123690 relate to similar optical filtration devices.
Exposé de l'invention Un objet de la présente invention est de remédier aux disfonctionnements dus à l'exposition de la rétine à certaines longueurs d'ondes, notamment celles comprises entre 400 et 560 nm. SUMMARY OF THE INVENTION An object of the present invention is to remedy malfunctions due to the exposure of the retina to certain wavelengths, in particular those between 400 and 560 nm.
La présente invention inclue donc un dispositif oculaire permettant de filtrer une certaine catégorie de longueurs d'ondes. Le dispositif oculaire comprend une surface de filtration, encore dénommée surface filtrante, pouvant être plane ou courbe, qui est disposée entre la rétine et la source lumineuse, de manière à limiter spécifiquement l'exposition à cette catégorie de longueurs d'ondes. The present invention therefore includes an ocular device for filtering a certain category of wavelengths. The ocular device comprises a filtration surface, also called filtering surface, which can be flat or curved, which is disposed between the retina and the light source, so as to specifically limit the exposure to this category of wavelengths.
De manière à améliorer le confort de l'utilisateur, la surface de filtration du dispositif oculaire est de préférence teintée d'une couleur jaune/orangée. Le matériau utilisé pour la surface de filtration peut être sélectionné parmi les matériaux communément utilisés pour les dispositifs optiques, tels que le verre, un polymère rigide tel que le polycarbonate, un polymère flexible, un dérivé de silicone, et un plastique rigide ou déformable. In order to improve the comfort of the user, the filtration surface of the ocular device is preferably tinted a yellow / orange color. The material used for the filtration surface may be selected from materials commonly used for optical devices, such as glass, a rigid polymer such as polycarbonate, a flexible polymer, a silicone derivative, and a rigid or deformable plastic.
La surface de filtration peut avoir une épaisseur homogène ou variable, et peut en plus ou alternativement avoir un indice de réfraction donné, ou présenter plusieurs indices de réfraction à des endroits différents de la surface. The filtration surface may have a homogeneous or variable thickness, and may additionally or alternatively have a given refractive index, or have several refractive indices at different locations on the surface.
Un second objet de l'invention est une méthode visant à rectifier ou rétablir les cycles de production de mélatonine et/ou d'autres composés organiques régulés par la luminosité, ou visant à prévenir des dérives du cycle circadien. La dopamine fait notamment partie des substances dont la production est régulée par l'exposition lumineuse. A second object of the invention is a method for rectifying or restoring the production cycles of melatonin and / or other organic compounds regulated by brightness, or aimed at preventing drifts of the circadian cycle. Dopamine is one of the substances whose production is regulated by light exposure.
Une méthode selon la présente invention peut être curative ou préventive. A method according to the present invention may be curative or preventive.
Description détaillée de l'invention L'objet de la présente invention est de remédier aux disfonctionnements dus à l'exposition de la rétine à certaines longueurs d'ondes, notamment celles comprises entre 400 et 560 nm. Un second aspect est de corriger les disfonctionnements dus à l'exposition de la rétine à certaines longueurs d'ondes, notamment celles comprises entre 400 et 560 nm. Un troisième aspect de l'invention est de prévenir les disfonctionnements dus à l'exposition de la rétine à certaines longueurs d'ondes, notamment celles comprises entre 400 et 560 nm. DETAILED DESCRIPTION OF THE INVENTION The object of the present invention is to remedy malfunctions due to the exposure of the retina to certain wavelengths, in particular those between 400 and 560 nm. A second aspect is to correct the malfunctions due to the exposure of the retina to certain wavelengths, in particular those between 400 and 560 nm. A third aspect of the invention is to prevent malfunctions due to the exposure of the retina to certain wavelengths, in particular those between 400 and 560 nm.
Pour ce faire, un dispositif oculaire permettant de filtrer une certaine catégorie de longueurs d'ondes fait ici l'objet de l'invention. Le dispositif oculaire comprend une surface de filtration, ou une surface filtrante, pouvant être plane ou courbe, qui est disposée entre la rétine et la source lumineuse, de manière à limiter spécifiquement l'exposition à cette catégorie de longueurs d'ondes. To do this, an ocular device for filtering a certain category of wavelengths is the subject of the invention. The ocular device comprises a filtration surface, or a filtering surface, which may be flat or curved, which is disposed between the retina and the light source, so as to specifically limit the exposure to this category of wavelengths.
Une catégorie de longueurs d'ondes dénote ici un ensemble de longueurs d'ondes répartie sur une plage ou plusieurs plages de longueurs d'ondes données. Les longueurs d'ondes filtrées sont de préférence comprises entre 400 et 560 nm, de manière plus préférentielle entre 460 et 520 nm. La plage de longueurs d'ondes le plus avantageusement filtrées est comprise entre 470 et 490 nm. A wavelength category here denotes a set of wavelengths spread over a range or several ranges of given wavelengths. The filtered wavelengths are preferably between 400 and 560 nm, more preferably between 460 and 520 nm. The most advantageously filtered wavelength range is between 470 and 490 nm.
Selon un aspect de l'invention, les longueurs d'ondes sont filtrées de manière à limiter faiblement leur transmission, c'est-à-dire à limiter leur transmission d'une valeur comprise entre 5% et environ 60% ou comprise entre 5% et80%, mais de manière préférentielle entre 10% et 50%, et de manière encore plus avantageuse comprise entre 15% et 30%. According to one aspect of the invention, the wavelengths are filtered so as to limit their transmission slightly, that is to say to limit their transmission by a value between 5% and approximately 60% or between 5% and 60%. % and 80%, but preferably between 10% and 50%, and even more advantageously between 15% and 30%.
Selon un autre aspect de l'invention, les longueurs d'ondes sont filtrées de manière à limiter significativement leur transmission, c'est-à-dire à limiter leur transmission d'une valeur comprise entre 80% et 98%, ou comprise entre 85% et 95%. According to another aspect of the invention, the wavelengths are filtered so as to significantly limit their transmission, that is to say to limit their transmission by a value between 80% and 98%, or between 85% and 95%.
Selon un autre aspect de l'invention, les longueurs d'ondes sont filtrées de manière à limiter totalement ou substantiellement totalement leur transmission, c'est-à-dire à limiter leur transmission d'une valeur supérieure à 98%.. According to another aspect of the invention, the wavelengths are filtered so as to totally or substantially limit their transmission, that is to say to limit their transmission by a value greater than 98%.
Selon un aspect de l'invention, un spectre étroit de longueur d'ondes est totalement filtré. En particulier, une plage de longueur d'onde restreinte, comprise entre environ 470 et environ 490 nm est filtrée de manière à limiter totalement ou substantiellement totalement leur transmission. En d'autres termes, l'invention permet de filtrer une plage de longueurs d'ondes comprises entre environ 470 et environ 490 nm de manière à limiter leur transmission d'une valeur supérieure à 98%. Selon un autre aspect de la présente invention, une large plage de longueurs d'ondes est filtrée faiblement ou significativement. En particulier, une plage de longueur d'ondes comprise entre environ 400 ou 420 nm, et environ 580 nm est filtrée de manière à limiter la transmission d'une valeur comprise entre 5 % et 60%, ou comprise entre environ 10% et environ 50%, ou encore d'une valeur comprise entre environ 15% et environ 30%, ou bien d'une valeur comprise entre environ 80% et 98%. La valeur de l'abaissement de la transmission peut être homogène sur toute la plage de longueurs d'ondes considérée, ou bien varier dans les limites de la fourchette donnée au sein de cette plage, soit entre 5% et 60%, entre 10% et 50%, ou entre 15% et 30%, ou encore entre 80% et 98%. Selon un autre aspect de l'invention, une plage restreinte de longueur de longueurs d'ondes est totalement filtrée ou substantiellement totalement filtrée, et une plage élargie de longueur d'ondes est faiblement ou significativement filtrée. En l'occurrence, le dispositif selon l'invention peut être optimisé pour filtrer une plage de longueur d'ondes comprise entre 470 et 490 nm de manière à limiter leur transmission d'une valeur supérieure à 98%, et à filtrer les longueurs d'ondes extérieures à cette plage et comprises entre 420 et 580 nm de manière à limiter leur transmission d'une valeur comprise entre environ5% et environ 60%, ou d'une valeur comprise entre environ 10% et environ 50%, ou comprise entre environ 15% et 30%, ou encore entre 80% et 98%. Selon un mode privilégié de l'invention, la transmission des longueurs d'ondes comprises entre 470 et 490 nm est limitée d'une valeur comprise entre 70% et 80%, et la transmission des autres longueurs d'ondes, pour autant qu'elles soient comprises entre 420 et 580 nm est limitée d'une valeur comprise entre 15% et -30%. According to one aspect of the invention, a narrow spectrum of wavelength is totally filtered. In particular, a restricted wavelength range of from about 470 to about 490 nm is filtered to completely or substantially limit their transmission. In other words, the invention makes it possible to filter a range of wavelengths between about 470 and about 490 nm so as to limit their transmission by a value greater than 98%. According to another aspect of the present invention, a wide range of wavelengths is filtered weakly or significantly. In particular, a wavelength range between about 400 or 420 nm, and about 580 nm is filtered so as to limit the transmission by a value between 5% and 60%, or between about 10% and about 50%, or from about 15% to about 30%, or from about 80% to 98%. The value of the lowering of the transmission can be homogeneous over the whole wavelength range considered, or vary within the limits of the range within this range, between 5% and 60%, between 10% and 50%, or between 15% and 30%, or between 80% and 98%. According to another aspect of the invention, a restricted range of wavelength length is completely filtered or substantially completely filtered, and an extended range of wavelength is weakly or significantly filtered. In this case, the device according to the invention can be optimized to filter a range of wavelengths between 470 and 490 nm so as to limit their transmission by a value greater than 98%, and to filter the lengths of waves outside this range and between 420 and 580 nm so as to limit their transmission by a value between about 5% and about 60%, or a value between about 10% and about 50%, or between about 15% and 30%, or between 80% and 98%. According to a preferred embodiment of the invention, the transmission of wavelengths between 470 and 490 nm is limited to a value between 70% and 80%, and the transmission of the other wavelengths, provided that they are between 420 and 580 nm is limited to a value between 15% and -30%.
Dans tout le texte, les termes « limiter la transmission >> doivent être entendus comme « abaisser la transmission >> ou « atténuer la transmission ». La valeur de la limitation est en référence par rapport à une transmission totale de 100%. Ainsi, limiter la transmission d'une valeur de 70% signifie que 30% de la longueur d'onde considérée est transmise à travers le dispositif de la présente invention. Throughout the text, the terms "limit transmission" should be understood as "lower transmission" or "mitigate transmission". The value of the limitation is in reference to a total transmission of 100%. Thus, limiting the transmission by a value of 70% means that 30% of the wavelength considered is transmitted through the device of the present invention.
Le dispositif oculaire peut prendre toute forme adaptée telle qu'une paire de lunettes, des lentilles oculaires ou une visière panoramique. Le dispositif oculaire est de préférence positionné ou positionnable devant les yeux de l'utilisateur, ou directement sur la rétine. Dans un mode de fonctionnement, particulier, il est envisagé de pouvoir greffer le dispositif dans la cornée ou sous la cornée. The ocular device can take any suitable form such as a pair of spectacles, eye lenses or a panoramic visor. The ocular device is preferably positioned or positionable in front of the user's eyes, or directly on the retina. In a particular mode of operation, it is envisaged that the device may be grafted into the cornea or under the cornea.
Le dispositif oculaire peut alternativement prendre la forme d'un écran, que l'on dispose devant la source lumineuse et à distance de l'utilisateur. Un tel écran peut par exemple être fixé directement sur la source lumineuse. La surface de filtration peut être un film que l'on dispose sur une autre surface, telle qu'un écran d'ordinateur ou de télévision, ou sur une fenêtre. Le filme peut être flexible et adhérer sur une autre surface grâce à des interactions électrostatiques. Le film peut être plus rigide de telle manière à pouvoir se maintenir au contact d'une autre surface. The ocular device may alternatively take the form of a screen, which is available in front of the light source and remote from the user. Such a screen can for example be fixed directly on the light source. The filtration surface may be a film that is available on another surface, such as a computer screen or TV, or on a window. The film can be flexible and adhere to another surface through electrostatic interactions. The film may be more rigid so that it can be held in contact with another surface.
Qu'il soit flexible ou rigide, le film peut alternativement être collé à une autre surface. Alternativement, le dispositif peut prendre la forme d'une fenêtre, telle qu'une fenêtre de véhicule ou d'habitation, ou de toute autre surface positionnable à une distance variable de la source lumineuse pour protéger un ou plusieurs utilisateurs. Whether flexible or rigid, the film can alternatively be glued to another surface. Alternatively, the device may take the form of a window, such as a vehicle or dwelling window, or any other positionable surface at a variable distance from the light source to protect one or more users.
La surface de filtration du dispositif oculaire peut donc prendre toutes les dimensions et avoir une épaisseur variable. L'épaisseur de la surface de filtration est de préférence comprise entre 0,1 mm et plus de 1 cm, de préférence entre 0,3 mm et 0,8 mm. La surface de filtration peut avoir une épaisseur homogène ou variable. L'épaisseur peut notamment être plus importante sur la partie centrale que sur les bords, ou moins importante. La variation d'épaisseur de la surface de filtration peut être progressive ou non progressive. La surface de filtration peut par exemple prendre la forme d'un verre de lunette avec une épaisseur comprise entre 0,2 et 0,4 mm sur sa partie périphérique, et une épaisseur comprise entre 0,4 et 0,6 mm sur sa partie centrale, et où la variation d'épaisseur entre sa partie périphérique et sa partie centrale est progressive. Le relief de la surface de filtration peut être adaptable à des utilisations particulières, notamment pour des corrections optiques de toute nature. La surface de filtration peut en plus ou alternativement avoir un indice de réfraction donné, ou présenter plusieurs indices de réfraction à des endroits différents de la surface. Ceci inclus tout gradient d'indices de réflexion. Ainsi, la surface de filtration de la présente invention peut présenter l'avantage d'une correction de défaut optique tel que la presbytie, la myopie, l'hypermétropie, l'astigmatisme, en combinaison avec la filtration sélective de certaines longueurs d'ondes. Alternativement, le dispositif selon l'invention peut être utilisé en combinaison avec un autre dispositif optique tel que des lunettes de vue, ou des lentilles de contact. The filtration surface of the ocular device can therefore take all dimensions and have a variable thickness. The thickness of the filtration surface is preferably between 0.1 mm and more than 1 cm, preferably between 0.3 mm and 0.8 mm. The filtration surface may have a homogeneous or variable thickness. The thickness may in particular be greater on the central part than on the edges, or less important. The variation in thickness of the filtration surface may be progressive or non-progressive. The filtration surface may for example take the form of a spectacle lens with a thickness of between 0.2 and 0.4 mm on its peripheral part, and a thickness of between 0.4 and 0.6 mm on its part. central, and where the thickness variation between its peripheral portion and its central portion is progressive. The relief of the filtration surface may be adaptable to particular uses, in particular for optical corrections of any kind. The filtration surface may additionally or alternatively have a given refractive index, or have several refractive indices at different locations on the surface. This includes any gradient of reflection indexes. Thus, the filtration surface of the present invention may have the advantage of an optical defect correction such as presbyopia, myopia, hyperopia, astigmatism, in combination with the selective filtration of certain wavelengths . Alternatively, the device according to the invention can be used in combination with another optical device such as eyeglasses, or contact lenses.
De manière à améliorer le confort de l'utilisateur, la surface de filtration du dispositif oculaire est de préférence teintée d'une couleur jaune/orangée. La coloration de la surface de filtration permet en l'occurrence de limiter l'éblouissement par les sources de lumières artificielles, en particulier dans un environnement nocturne, où le contraste entre la source lumineuse et l'environnement est accru. C'est le cas notamment lors de l'utilisation d'un dispositif lumineux, tel qu'un ordinateur ou un téléphone mobile, dans une pièce sombre. La coloration est de préférence incluse dans la matière de la surface filtrante, de manière à limiter sa sensibilité à l'usure et aux éraflures. In order to improve the comfort of the user, the filtration surface of the ocular device is preferably tinted a yellow / orange color. The coloration of the filtering surface makes it possible in this case to limit glare from artificial light sources, in particular in a nocturnal environment, where the contrast between the light source and the environment is increased. This is particularly the case when the use of a light device, such as a computer or a mobile phone, in a dark room. The coloring is preferably included in the material of the filtering surface, so as to limit its sensitivity to wear and scratches.
Le matériau utilisé pour la surface de filtration peut être sélectionné parmi les matériaux communément utilisés pour les dispositifs optiques. La surface de filtration peut être notamment constituée de verre, d'un polymère rigide tel que le polycarbonate, d'un polymère flexible, d'un dérivé de silicone, d'un plastique rigide ou déformable. La surface de filtration peut alternativement être constituée de plusieurs matériaux sélectionnés parmi le verre, un polymère rigide comme que le polycarbonate, un polymère flexible, un dérivé de silicone, un plastique rigide ou déformable. Les matériaux composant la surface de filtration peuvent être juxtaposés, de manière à conférer des propriétés variables en fonction de l'endroit considéré de la surface de filtration. Par exemple, la surface de filtration peut avoir une partie centrale rigide, et une partie périphérique souple, ou inversement. Les matériaux composant la surface de filtration peuvent être superposés en couches successives. La surface de filtration peut alors contenir plusieurs couches, où l'une au moins de ces couches de matériaux permet de filtrer sélectivement les longueurs d'ondes visées. The material used for the filtration surface may be selected from materials commonly used for optical devices. The filtration surface may in particular be made of glass, a rigid polymer such as polycarbonate, a flexible polymer, a silicone derivative, a rigid or deformable plastic. The filtration surface may alternatively consist of several materials selected from glass, a rigid polymer such as polycarbonate, a flexible polymer, a silicone derivative, a rigid or deformable plastic. The materials composing the filtration surface may be juxtaposed, so as to confer variable properties depending on the considered location of the filtration surface. For example, the filtration surface may have a rigid central portion, and a flexible peripheral portion, or vice versa. The materials composing the filtration surface can be superimposed in successive layers. The filtration surface can then contain several layers, where at least one of these layers of materials can selectively filter the wavelengths concerned.
Le dispositif peut présenter plusieurs surfaces de filtration, dont l'une est placée entre la source lumineuse et la rétine. La ou les surfaces de filtration supplémentaires peuvent être disposées latéralement, de manière à filtrer les émissions lumineuses indirectes, ou résiduelles, ou en cas de plusieurs émissions lumineuses. The device may have a plurality of filtration surfaces, one of which is placed between the light source and the retina. The additional filtering surface (s) may be arranged laterally, so as to filter the indirect or residual light emissions or in the case of several light emissions.
Un second objet de la présente invention est une méthode curative visant à rectifier ou rétablir les cycles de production de mélatonine et/ou d'autres composés organiques régulés par l'exposition à la lumière. Une méthode curative selon la présente invention comprend notamment le port séquentiel du dispositif oculaire de filtration pendant une durée prédéterminée, et à une fréquence prédéterminée. La durée prédéterminée peut être constante pendant toute la période d'utilisation, ou bien variable entre le début et la fin de la période d'utilisation séquentielle. Elle peut être par exemple comprise entre 15 minutes et 5 heures. La fréquence d'utilisation peut également être régulière ou variable. Une fréquence régulière peut par exemple être de 24, ou 48 heures. Une fréquence variable peut par exemple être comprise entre 24 heures et 72 heures, entre le début de l'utilisation et la fin de l'utilisation. La méthode curative selon la présente invention peut en outre comprendre plusieurs phases, chacune des phases d'utilisation ayant une durée et une fréquence propre. A second object of the present invention is a curative method for rectifying or restoring the cycles of production of melatonin and / or other organic compounds regulated by exposure to light. A curative method according to the present invention comprises in particular the sequential port of the ocular filtration device for a predetermined duration, and at a predetermined frequency. The predetermined duration can be constant throughout the period of use, or variable between the beginning and the end of the period of sequential use. It can be for example between 15 minutes and 5 hours. The frequency of use can also be regular or variable. A regular frequency may for example be 24, or 48 hours. A variable frequency may for example be between 24 hours and 72 hours, between the start of use and the end of use. The curative method according to the present invention may further comprise several phases, each phase of use having a duration and a natural frequency.
Un exemple de méthode curative selon la présente invention comprend une première phase d'utilisation où la durée et la fréquence d'utilisation sont constantes, une seconde phase d'utilisation où l'une ou l'autre de la durée et la fréquence varie progressivement, et une troisième phase d'utilisation où fréquence et durée d'utilisation sont à nouveau constantes. An exemplary curative method according to the present invention comprises a first phase of use where the duration and the frequency of use are constant, a second phase of use where one or the other of the duration and the frequency varies gradually , and a third phase of use where frequency and duration of use are again constant.
L'utilisation curative du dispositif oculaire de filtration selon la méthode de la présente invention peut par exemple être la suivante : - Une première phase d'utilisation, où l'utilisateur porte le dispositif de filtration pendant trois heures chaque soir deux heures avant l'heure du coucher, pendant une semaine, The curative use of the ocular filtration device according to the method of the present invention may for example be the following: - A first phase of use, where the user wears the filtration device for three hours each evening two hours before bedtime, for a week,
- Une seconde phase d'utilisation, où l'utilisateur porte le dispositif de filtration pendant une durée qui décroit d'une valeur donnée tous les trois soirs. La valeur de la diminution peut être d'une demi-heure, ou d'une heure ou de toute valeur intermédiaire. L'utilisateur portera le dispositif pendant 2h30 trois soirs de suite deux heures avant l'heure habituelle du coucher, puis pendant 2h les trois soirs suivants, et ce jusqu'à une limite donnée de durée d'utilisation, qui peut être par exemple d'une heure.  - A second phase of use, where the user wears the filter device for a period that decreases by a given value every third night. The value of the decrease can be half an hour, or a time, or any intermediate value. The user will wear the device for 2h30 three nights in a row two hours before the usual bedtime, then for 2h the following three nights, up to a given limit of duration of use, which may be for example d 'one o'clock.
- Une dernière phase d'utilisation, où l'utilisateur porte le dispositif oculaire de filtration pendant une heure, à une fréquence constante de 48 heures, pendant une semaine.  - A final phase of use, where the user wears the ocular filtration device for one hour, at a constant frequency of 48 hours, for a week.
La méthode curative selon la présente invention peut par exemple être appliquée pour les troubles du sommeil chroniques, ou pour un meilleur rétablissement du rythme circadien après un long voyage induisant un décalage horaire. The curative method according to the present invention can for example be applied for chronic sleep disorders, or for a better recovery of the circadian rhythm after a long trip causing a jet lag.
Dans un mode de fonctionnement particulier, une fois le rythme circadien rétabli, l'utilisateur en conserve le bénéfice sans qu'il ne soit nécessaire de recourir à l'utilisation du présent dispositif. C'est notamment le cas lors d'une utilisation curative. In a particular mode of operation, once the circadian rhythm is restored, the user retains the benefit without it being necessary to use the present device. This is particularly the case during curative use.
La méthode selon la présente invention peut également être utilisée à des fins préventives. L'utilisateur peut en l'occurrence porter le dispositif à heure fixe chaque jour, ou lors d'une exposition aux longueurs d'ondes nocives. La méthode selon l'invention peut être utilisée pour réguler les métabolismes liés directement ou indirectement à la production ou à l'inhibition de mélatonine. La présente méthode permet ainsi d'abaisser le rythme cardiaque et/ou la température corporelle. La méthode selon l'invention peut être utilisée pour réguler les métabolismes liés directement ou indirectement à la production ou à l'inhibition de dopamine. L'utilisation du dispositif oculaire de filtration selon une méthode de l'invention permet ainsi d'influencer l'évolution de la myopie, et en particulier de ralentir l'évolution de la myopie. L'utilisation du dispositif oculaire de filtration selon une méthode de l'invention permet également d'influencer l'évolution de l'astigmatisme, et en particulier de ralentir l'évolution de l'astigmatisme. The method according to the present invention can also be used for preventive purposes. The user can in this case wear the device at a fixed time each day, or during exposure to harmful wavelengths. The method according to the invention can be used to regulate metabolisms directly or indirectly related to the production or inhibition of melatonin. The present method thus makes it possible to lower the heart rate and / or the body temperature. The method according to the invention can be used to regulate metabolisms directly or indirectly related to the production or inhibition of dopamine. The use of the filtering eye device according to a method of the invention thus makes it possible to influence the evolution of myopia, and in particular to slow the evolution of myopia. The use of the ocular filtration device according to a method of the invention also makes it possible to influence the evolution of astigmatism, and in particular to slow down the evolution of astigmatism.
Le dispositif oculaire de filtration peut être utilisé pendant des périodes nocturnes ou des périodes diurnes, ou une combinaison des deux. The ocular filtration device can be used during nocturnal periods or diurnal periods, or a combination of both.

Claims

Revendications claims
1 . Dispositif oculaire de filtration comprenant une surface de filtration de la lumière caractérisé en ce que cette surface de filtration atténue ou élimine la transmission d'une plage de longueur d'ondes comprises entre 400 et 580 nm, et en ce que cette surface est teintée d'une couleur jaune-orangée. 1. An ocular filtration device comprising a light filtering surface characterized in that said filtering surface attenuates or eliminates transmission from a wavelength range of 400 to 580 nm, and that said surface is tinted with a yellow-orange color.
2. Dispositif selon la revendication 1 , caractérisé en ce que la surface de filtration est constituée d'un matériau ou d'une combinaison de matériaux sélectionnés parmi un polymère, le verre, ou un plastique. 2. Device according to claim 1, characterized in that the filtration surface is made of a material or a combination of materials selected from a polymer, glass, or a plastic.
3. Dispositif selon l'une ou l'autre des revendications précédentes, caractérisé en ce que la coloration de la surface de filtration est incluse dans le matériau de ladite surface de filtration. 3. Device according to either of the preceding claims, characterized in that the coloration of the filtration surface is included in the material of said filtration surface.
4. Dispositif selon l'une ou l'autre des revendications précédentes, caractérisé en ce que les longueurs d'ondes filtrées sont comprises entre 420 et 580 nm, et en ce que la transmission de lumière est atténuée d'une valeur comprise entre 15% et 30% 4. Device according to one or other of the preceding claims, characterized in that the filtered wavelengths are between 420 and 580 nm, and in that the light transmission is attenuated by a value between % and 30%
5. Dispositif selon l'une ou l'autre des revendications précédentes, caractérisé en ce que les longueurs d'ondes filtrées sont comprises entre 470 et 490 nm, et en ce que la transmission de lumière est atténuée d'une valeur comprise entre 70% et 90%. 5. Device according to one or other of the preceding claims, characterized in that the filtered wavelengths are between 470 and 490 nm, and in that the transmission of light is attenuated by a value of between 70 % and 90%.
6. Dispositif selon l'une ou l'autre des revendications précédentes, caractérisé en ce que la surface de filtration est sélectionnée parmi un verre de lunette, une lentille, une visière. 6. Device according to either of the preceding claims, characterized in that the filtration surface is selected from a spectacle lens, a lens, a visor.
7. Méthode de régulation du rythme circadien, caractérisée par la filtration sélective d'une certaine gamme de longueurs d'ondes par l'utilisation du dispositif de filtration selon l'une ou l'autre des revendications 1 à 6. 7. Circadian rhythm regulation method, characterized by the selective filtration of a certain range of wavelengths by the use of the filter device according to one or more of claims 1 to 6.
8. Méthode selon la revendication 7, caractérisée en ce que ladite méthode comprend une phase d'utilisation du dispositif selon l'une ou l'autre des revendications 1 à 6, où au moins l'une ou l'autre de la durée et de la fréquence d'utilisation du dispositif est variable. 8. Method according to claim 7, characterized in that said method comprises a phase of use of the device according to one or other of the Claims 1 to 6, wherein at least one or other of the duration and frequency of use of the device is variable.
9. Méthode selon la revendication 8, comprenant en outre une phase d'utilisation du dispositif selon l'une ou l'autre des revendications 1 à 6, où la durée et la fréquence d'utilisation sont constantes. The method of claim 8, further comprising a phase of use of the device according to any one of claims 1 to 6, wherein the duration and frequency of use are constant.
10. Méthode selon la revendication 7 ou 8, comprenant : The method of claim 7 or 8, comprising:
- Une première phase d'utilisation du dispositif tel que décrit dans les revendications 1 à 6, où la durée et la fréquence d'utilisation sont constante et prédéterminées ; - A first phase of use of the device as described in claims 1 to 6, wherein the duration and frequency of use are constant and predetermined;
- Une seconde phase d'utilisation du dispositif tel que décrit dans les revendications 1 à 6, où au moins l'une ou l'autre de la durée et de la fréquence d'utilisation est variable,  - A second phase of use of the device as described in claims 1 to 6, wherein at least one or other of the duration and frequency of use is variable,
- Une troisième d'utilisation du dispositif tel que décrit dans les revendications 1 à 6, où la durée et la fréquence d'utilisation sont constante et prédéterminées.  - A third use of the device as described in claims 1 to 6, wherein the duration and frequency of use are constant and predetermined.
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