WO2018040078A1 - Dispositif portable de surveillance de la température de l'œil et système associé - Google Patents

Dispositif portable de surveillance de la température de l'œil et système associé Download PDF

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Publication number
WO2018040078A1
WO2018040078A1 PCT/CN2016/098004 CN2016098004W WO2018040078A1 WO 2018040078 A1 WO2018040078 A1 WO 2018040078A1 CN 2016098004 W CN2016098004 W CN 2016098004W WO 2018040078 A1 WO2018040078 A1 WO 2018040078A1
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WO
WIPO (PCT)
Prior art keywords
temperature
eye
frame
signal processing
processing circuit
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Application number
PCT/CN2016/098004
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English (en)
Chinese (zh)
Inventor
赖弘基
邱琬婷
杨自森
Original Assignee
清弘生医股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 清弘生医股份有限公司 filed Critical 清弘生医股份有限公司
Priority to PCT/CN2016/098004 priority Critical patent/WO2018040078A1/fr
Publication of WO2018040078A1 publication Critical patent/WO2018040078A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue

Definitions

  • the present invention relates to a wearable eye temperature monitoring device, and more particularly to a monitoring device for eye surface temperature that can be attached or combined with glasses.
  • the surface temperature of the eye is the state of the muscles or layers of the eye that respond to the eyeball, so it can be used as an important indicator of eye health or disease.
  • ⁇ muscle tension
  • the ocular surface temperature will increase.
  • ciliary muscle spasm causes myopia, which causes the ocular surface temperature to rise.
  • the amount of tears flowing to the ocular surface is reduced, which causes the temperature of the eyeball to decrease. Therefore, an increase or decrease in the temperature of the eyeball can be used to determine whether the eye is healthy, close to the lesion, or has developed a lesion.
  • 3C products is quite common. Many users often watch images displayed by 3C products, and often cause eye myopia or dry eye lesions.
  • US Published Patent Application No. US 2015/0342465 discloses a desktop type eye temperature measuring device which is bulky and cannot be carried, and requires the operation of the device by a professional technician to perform eye temperature measurement in a short period of time. Eye temperature actually varies with time, environment and physiological changes. The device does not collect eye temperature changes for a long time and is therefore not suitable for eye disease research and treatment.
  • US Patent No. 2010/0234717, US 2013/0041245, and PCT International Patent No. WO 03/001991 propose a contact lens in combination with an electronic pressure sensor for measuring the pressure in the eye.
  • US Patent No. 2002/0049389 also discloses a contact lens in combination with a thermistor sensor (Instruction [0133] [0134] [section] for measuring the temperature in the eye.
  • the power of the circuits in the contact lenses can be provided by the internal micro-battery or the external coil, and the micro-cell or the external coil may cause changes in the eye temperature, that is, the correctness of the measurement results.
  • eye medical or vision correction requires a device that can detect the surface temperature of the eye, which can be widely used in preventive medicine and corrective monitoring.
  • the present application provides a wearable eye temperature monitoring device and a system thereof, which can be used for preventive medicine and corrective monitoring by recording the surface temperature of the eye by means of a device that can be attached or combined with glasses at a constant time.
  • the present invention provides an embodiment of a wearable eye temperature monitoring device for non-contact measurement of the surface temperature of an eye, comprising: a frame comprising a chamber and at least one opening; and an eye temperature monitoring
  • the module includes: at least one first temperature sensor disposed in the chamber, through the opening for measuring a surface temperature of the eye, and generating a plurality of electrical signals; and a temperature signal processing circuit for receiving and processing the Multiple electrical signals and wireless signals are transmitted externally.
  • the temperature signal processing circuit includes: a signal processing circuit that reads and records an electrical signal generated by the first temperature sensor; and a wireless transmission and reception circuit. The output signal of the signal processing circuit is replaced by a wireless signal.
  • a coherent cold plate is further included, driven by the temperature signal processing circuit to reduce the temperature of the air surrounding the eye.
  • a second temperature sensor is further included to measure the temperature of the skin, thereby compensating or calibrating the surface temperature of the eye.
  • the frame is a removable portion of a frame.
  • the frame is a frame
  • the first temperature sensor is disposed in the housing of the frame
  • the temperature signal processing circuit is disposed in a protective housing that can be coupled to the frame.
  • the temperature signal processing circuit can be electrically connected to the temperature sensor through a plurality of metal contacts on the frame.
  • the frame further includes: an end cover, the first temperature sensor is fixed to the end cover; and a spherical housing coupled with the end cover, and the frame can be rotated relative to the frame motion.
  • the temperature signal processing circuit and the first temperature sensor are disposed in the chamber.
  • a light-emitting element disposed on the frame further includes a light source or a surface of the eye having a higher or lower surface temperature, wherein the light-emitting element emits light or a pattern.
  • the method further includes a plurality of lenses disposed in the frame and a transparent display element formed on the lens, wherein the transparent surface temperature of the eye is higher or lower than a preset value, and the transparent The display component emits light, patterns, or text.
  • the number of the first temperature sensors is plural, and is used to separately measure surface temperatures of the plurality of points of the eye and its eyelids.
  • the number of the first temperature sensors is plural, and is used to continuously and separately measure the surface temperatures of the plurality of points of the eye.
  • the present invention further provides an embodiment of a wearable eye temperature monitoring system for non-contact measurement of the surface temperature of the eye, comprising: a frame comprising a chamber and at least one opening; an eye temperature monitoring module,
  • the method includes: at least one first temperature sensor disposed in the chamber, configured to measure a surface temperature of the eye and generate a plurality of electrical signals; and a temperature signal processing circuit to receive and process the plurality of Electrical signals, and transmitting wireless signals to the outside; and a mobile communication device, The wireless signal is accepted and the surface temperature of the eye is analyzed and displayed.
  • the temperature signal processing circuit includes: a signal processing circuit that reads and records an electrical signal generated by the first temperature sensor; and a wireless transmission and reception circuit that converts the signal processing circuit The output signal is a wireless signal.
  • a coherent cold plate is further included, driven by the temperature signal processing circuit to reduce the temperature of the air surrounding the eye.
  • a second temperature sensor is further included to measure the temperature of the skin, thereby compensating or calibrating the surface temperature of the eye.
  • the frame is a removable portion of a frame.
  • the frame is a frame
  • the first temperature sensor is disposed in the housing of the frame
  • the temperature signal processing circuit is disposed in a protective housing that can be coupled to the frame.
  • the temperature signal processing circuit can be electrically connected to the temperature sensor through a plurality of metal contacts on the frame.
  • the frame further includes: an end cover, the first temperature sensor is fixed to the end cover; and a spherical housing coupled with the end cover, and the frame can be rotated relative to the frame motion.
  • the temperature signal processing circuit and the first temperature sensor are disposed in the chamber.
  • a light-emitting element disposed on the frame further includes a light source or a surface of the eye having a higher or lower surface temperature, wherein the light-emitting element emits light or a pattern.
  • the method further includes a plurality of lenses disposed in the frame and a transparent display element formed on the lens, wherein the transparent surface temperature of the eye is higher or lower than a preset value, and the transparent The display component emits light, patterns, or text.
  • the number of the first temperature sensors is plural, and is used to respectively measure the surface temperatures of the plurality of points of the eye and the eyelid thereof, wherein the mobile communication device analyzes and displays the blink of the eye. Status or frequency.
  • the number of the first temperature sensors is plural, and is used to continuously and separately measure the surface temperatures of the plurality of points of the eye, wherein the mobile communication device analyzes and displays the rotation of the eyes. direction.
  • FIG. 1 is a schematic diagram of a wearable eye temperature monitoring device in accordance with an embodiment of the present invention.
  • FIG. 2 is an exploded view of the wearable eye temperature monitoring device of FIG. 1.
  • 3A and 3B are cross-sectional views showing the angle at which the combination of the spherical housing 1143 and the end cap 1144 can be adjusted.
  • FIG. 4 is a block diagram of an eye temperature monitoring circuit module in accordance with an embodiment of the present invention.
  • FIG. 5 is a schematic diagram of a wearable eye temperature monitoring device according to another embodiment of the present invention.
  • FIG. 6 is a schematic diagram of a wearable eye temperature monitoring device in accordance with yet another embodiment of the present invention.
  • the wearable eye temperature monitoring device 10 includes a frame 11, a pair of lenses 12, and an eye temperature monitoring circuit module 13.
  • the eye temperature monitoring circuit module 13 is disposed substantially in the frame 11, measures the surface temperature of the eye, and can process and transmit the signal of the measured surface temperature.
  • the frame 11 has a mirror ring (not shown) for fixing the lens 12, a nose pad 111, a front temple 112 and a rear temple 113.
  • a transparent mask 14 may be placed in front of the lens 12, so as to block the cooling caused by the wind blowing.
  • the frame is a frame, and the frame is not limited by the type of the glasses.
  • the frame that can be fixed near the eyelid or can be combined with the eyeglasses is the protection scope of the invention claimed in the present application.
  • FIG. 2 is an exploded view of the wearable eye temperature monitoring device of FIG. 1.
  • the upper cover 1141 and the lower bracket 1142 can be coupled to each other, and have a chamber therein, thereby a plurality of temperature sensors 131 (or at least one temperature sensor) and a temperature signal processing circuit 132 (as shown A circuit board and its upper electronic components are housed and protected therein.
  • the temperature sensor 131 can sense the surface temperature of the eye using the principles of thermal radiation, heat convection, or heat conduction, such as an infrared sensor.
  • the temperature sensors 131 are respectively fixed in the end cover 1144, and the spherical housing 1143 can be combined with the end cover 1144.
  • the combined body can be used to adjust the position of the temperature sensor 131, thereby effectively aligning the surface of the eye.
  • the upper part is measured for temperature (see Figures 3A and 3B).
  • the lower bracket 1142 has a plurality of openings 1145 for the end cap 1144 to be exposed, and the end cap 1144 can be rotated or moved relative to the opening 1145.
  • the front lens 112 includes a side cover 1121 and a base 1122.
  • the side cover 1121 and the base 1122 can be coupled to each other, and a receptacle is disposed therein, and a uniform cold sheet 16 is accommodated therein.
  • the cooling plate 16 can be driven to start to operate, and the heat of the air inside the lens 14 can be taken away, which can be indirectly reduced. Eye temperature.
  • the cooling fins 16 may be a Thermoelectric Cooling Module, a Thermoelectric Cooling Chip, a cryogenic wafer, a Thermoelectric Cooler, a Peltier Cooler, and a Pierre. Peltier Cell or Heat Pump. That is, the thermoelectric materials which can convert the thermal energy and the electric energy into each other are the protection scope of the invention claimed in the present application.
  • 3A and 3B are cross-sectional views showing the angle at which the combination of the spherical housing 1143 and the end cap 1144 can be adjusted.
  • the spherical housing 1143 and the end cover 1144 are engaged with each other, and the temperature sensor 131 is fixed in the end cover 1144.
  • the end of the end cover 1144 has a through hole 1146.
  • the temperature sensor 131 can detect the external temperature through the through hole 1146, for example, detecting the heat radiation emitted from the surface of the eye.
  • the spherical housing 1143 has a protrusion 1147 for allowing signal lines and power lines (not shown) of the temperature sensor 131 to pass through, and is connected to the contacts of the circuit board in the temperature signal processing circuit 132.
  • the protruding portion 11147 can limit the rotation angle of the combined body of the spherical housing 1143 and the end cover 1144 and prevent the detachment from the through hole 1146.
  • the upper cover body 1141 has a rib 1148 to restrain the spherical housing 1143 from rotating only, and the protruding portion 1147 is limited by the rib 1148 and the lower bracket 1142, and the maximum rotation angle of the spherical housing 1143 is as shown in FIGS. 3A and 3B.
  • the present embodiment is not limited thereto, and any mechanism or structure in the form of a ball joint is the scope of protection claimed in the present application.
  • the upper cover 1141 and the lower bracket 1142 in the above embodiment may be coupled to each other, and the plurality of temperature sensors 131 and the temperature signal processing circuit 132 are accommodated in the space in the combination.
  • This entire combination can be fixed to the frame 11 (screwed) or can be detached from the frame 11, for example, by a snap mechanism. That is, in the detachable embodiment, the upper cover 1141, the lower bracket 1142, and the eye temperature monitoring circuit module 13 are regarded as a complete wearable eye temperature monitoring device, and the frame 11 and the lens 12 are selectable. section.
  • the eye temperature monitoring circuit module 43 includes a plurality of temperature sensors 431, a multiplexer 432, a micro control unit (MCU) 433, and a Bluetooth wireless circuit 434.
  • MCU micro control unit
  • this embodiment is merely an example.
  • the scope of protection claimed in this application is not limited to this.
  • the Bluetooth wireless circuit 434 can be replaced by other RF wireless circuits, and the multiplexer 432 and the micro control unit 433 can be integrated into a signal processor or a central processing unit.
  • a plurality of temperature sensors 431 are aligned with different portions of the surface of the eye to detect the temperature of the portions and output the measured temperature as an analog signal.
  • the multiplexer 432 may select an electrical signal generated by one of the plurality of temperature sensors 431 according to the control of the micro control unit 433, and transmit the electrical signal to the micro control unit 433, for example, sequentially and repeatedly selecting a plurality of temperatures.
  • the micro control unit 433 can read, record, and temporarily store the above electrical signals, or can further process the signals, such as signal conversion or signal compensation.
  • the Bluetooth wireless circuit 434 receives the processed signals output from the micro control unit 433 and wirelessly transmits it to the outside.
  • the mobile phone 49, the computer (not shown), the specific analysis device (not shown) or the mobile communication device (not shown) receive the Bluetooth wireless signal or other protocol format signals, and then use the application (App) or the analysis software to The signal representing the temperature of the eye is analyzed and compared, and then the measurement data of the surface temperature of the eye is displayed in words or figures, or whether there is an abnormal judgment result.
  • the user can also set the parameters in the micro control unit 433 by using the application of the mobile phone 49, or set the temperature signal processing circuit.
  • the usage mode of 132 for example, the measurement period or sampling frequency, and the like.
  • FIG. 5 is a schematic diagram of a wearable eye temperature monitoring device according to another embodiment of the present invention.
  • the wearable eye temperature monitoring device 50 includes a frame 51, a pair of lenses 52, and an eye temperature monitoring circuit module (including a plurality of temperature sensors 531 and temperature signal processing circuits 532).
  • the eye temperature monitoring circuit module is disposed substantially in the frame 51, measures the surface temperature of the eye, and can process and transmit the signal of the measured surface temperature.
  • the frame 51 has a mirror ring 510 and a temple 512 for fixing the lens 52.
  • the temperature signal processing circuit 532 may be an Application-Specific IC (ASIC) component.
  • ASIC Application-Specific IC
  • the upper and lower frames of the mirror ring 510 are provided with a plurality of temperature sensors 531.
  • the frame has an opening to expose the rotatable end cover 5144, and a temperature sensor is fixed in each end cover 5144 (see the aforementioned end).
  • the description of the cover 1144) allows adjustment of the angle at which the temperature sensor is aligned.
  • the temperature signal processing circuit 532 can receive the electrical signal generated by the temperature sensor, perform signal processing, and wirelessly transmit to the mobile phone or computer.
  • a temperature sensor 531' can be disposed on the nose bridge portion connected to the center of the two mirror ring 510 (different from the temperature sensor 531, which can be named as the second temperature).
  • a sensor for measuring the temperature of the skin.
  • the skin temperature can be used as a reference value to determine whether the user has abnormal body temperature, such as fever or temperature loss (high or below a preset value), thereby compensating or calibrating the surface temperature of the measured eye.
  • the nose bridge portion has an opening to expose the rotatable end cap 5145, and a temperature sensor is fixed in the end cap 5145 (see the related description of the end cap 1144), so that the angle at which the temperature sensor is aligned can be adjusted.
  • the temperature signal processing circuit 532 drives a light-emitting element 54 to generate a warning light 541 on the lens 52, thereby notifying the user to stop watching the screen or leaving the high temperature environment.
  • a transparent flexible display element (not shown; or a portion such as light and shadow 541), such as a soft electronic book, may be formed on the lens 52, and the display element is driven by the temperature signal processing circuit 532 to generate a warning pattern or Text.
  • an organic light emitting display or a liquid crystal display is formed on the edge of the viewing angle of the lens 52.
  • the wearable eye temperature monitoring device 50 with the temperature measuring function can be worn for a long time in normal life or work, and the subject does not need to be limited by the temperature measuring tool and can only reside in the tested area. For example, it is located in front of the infrared camera used in the prior art, so it is convenient for activity, sleep or long-term measurement, thereby increasing the accuracy of the judgment result.
  • FIG. 6 is a schematic diagram of a wearable eye temperature monitoring device in accordance with yet another embodiment of the present invention.
  • the temperature signal processing circuit 632 of the wearable eye temperature monitoring device 60 in this embodiment is disposed in the protective casing (the same as the temperature signal processing circuit 532 of FIG. 5), and can be detached, on the temple 612.
  • a plurality of metal contacts 615 or gold fingers are provided, whereby the temperature signal processing circuit 632 can receive electrical signals from a plurality of temperature sensors in the upper and lower bezels of the mirror ring 610.
  • the wearable eye temperature monitoring device provided by the present application can be applied not only to the monitoring of eye temperature changes of myopia or dry eye, but also to monitoring and judging abnormal conditions (or symptoms) of other eye temperature changes.
  • the plurality of temperature sensors 131 can respectively align different points of the left and right eyeballs, for example, the three left temperature sensors 131 are respectively aligned with the positions of the left eyeball near the inner corner of the eye, the middle and the outer corner of the eye.
  • more temperature sensors can monitor the temperature of more points on the eyeball, for example, close to the upper and lower eyelids.
  • the temperature of the eyelid is different from the surface temperature of the eyeball.
  • the temperature sensor at different points will measure the temperature of the eyelid, that is, measured at the previous time point.
  • the surface temperature of the eyeball changes instantaneously. According to the change of temperature measured at each point and the time point at which different point changes occur, it can be judged whether there is eyelid closure and its frequency of occurrence. If the user of the wearable eye temperature monitoring device has the symptoms of eyelids (commonly known as eye jumping), this symptom refers to the phenomenon that the eyelid muscles are not self-controlling, and can occur in both eyes at the same time, and there are also phenomena in which the left and right eyes respectively jump.
  • the wearable eye temperature monitoring device can detect the number and frequency of each blink of the two eyes, and can be compared with the threshold of the set number or frequency. If it is larger than above, it can be judged that there is a flaw. Of course, it is also possible to set a plurality of thresholds based on actual experience, thereby judging whether the condition of the eyelid symptoms is serious or slight.
  • the wearable eye temperature monitoring device can also be judged by the distribution of temperature at different points. This symptom or phenomenon, that is, the monitoring point and other points at the unclosed area are measured on the surface of the eyelid The temperature is different.
  • more temperature sensors can monitor the temperature of more points on the eyeball. If the user suddenly has a rapid rotation of the eyeball or a phenomenon of fighting the eye, it can be judged by the direction or trend of the temperature change of the multiple points. Rotation, or even the direction of rotation, that is, the highest temperature point (or low temperature point) of the eyeball occurs with adjacent monitoring points over time.
  • the wearable eye temperature monitoring device can monitor for a long time and judge whether or not the symptoms are met according to the set conditions.
  • the wearable eye temperature monitoring device and system thereof of the present invention can be used for preventive medicine and corrective monitoring by recording the surface temperature of the eye by means of a device that can be attached or combined with glasses at a constant time.

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Abstract

La présente invention concerne un dispositif portable de surveillance de la température de l'œil (10, 50, 60), apte à être fixé à proximité des cavités orbitaires, ou étant combiné à des lunettes pour mesurer les températures de surface des globes oculaires. Le dispositif (10, 50, 60) comprend un corps de cadre et un module de circuit de surveillance de température de l'œil (13, 43) disposé dans le corps de cadre. Le module de circuit de surveillance de température de l'œil (13, 43) comprend une pluralité de capteurs de température (131, 431, 531, 531'), un circuit de traitement de signal (132, 532, 632), et un circuit d'émission et de réception sans fil. La pluralité de capteurs de température (131, 431, 531, 531') sont alignés avec des surfaces oculaires pour mesurer leurs températures. Le circuit de traitement de signal (132, 532, 632) lit et enregistre les signaux électriques émis par la pluralité de capteurs de température (131, 431, 531, 531') et transmet les signaux sans fil à l'extérieur au moyen du circuit d'émission et de réception sans fil.
PCT/CN2016/098004 2016-09-05 2016-09-05 Dispositif portable de surveillance de la température de l'œil et système associé WO2018040078A1 (fr)

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PCT/CN2016/098004 WO2018040078A1 (fr) 2016-09-05 2016-09-05 Dispositif portable de surveillance de la température de l'œil et système associé

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PCT/CN2016/098004 WO2018040078A1 (fr) 2016-09-05 2016-09-05 Dispositif portable de surveillance de la température de l'œil et système associé

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12001086B2 (en) 2020-09-22 2024-06-04 International Business Machines Corporation Cooling system for smart contact lenses

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CN1822788A (zh) * 2003-06-10 2006-08-23 福威光学公司 非侵入性血糖测定
US20080174733A1 (en) * 2007-01-18 2008-07-24 United Integrated Services Co., Ltd. Method of using infrared thermal imager to diagnose eye diseases and the device thereof
CN101272727A (zh) * 2005-09-27 2008-09-24 潘尼公司 用于控制外部单元的装置
CN103300822A (zh) * 2003-02-26 2013-09-18 马尔西奥·马克·奥雷利奥·马丁斯·阿布雷乌 测量生物学参数的仪器和方法
US20150112153A1 (en) * 2013-10-22 2015-04-23 Neba Health, Llc System and method for a compact eeg headset
CN104586349A (zh) * 2013-10-31 2015-05-06 赖弘基 眼睛温度的测量与分析系统、接收分析装置及其方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103300822A (zh) * 2003-02-26 2013-09-18 马尔西奥·马克·奥雷利奥·马丁斯·阿布雷乌 测量生物学参数的仪器和方法
CN1822788A (zh) * 2003-06-10 2006-08-23 福威光学公司 非侵入性血糖测定
CN101272727A (zh) * 2005-09-27 2008-09-24 潘尼公司 用于控制外部单元的装置
US20080174733A1 (en) * 2007-01-18 2008-07-24 United Integrated Services Co., Ltd. Method of using infrared thermal imager to diagnose eye diseases and the device thereof
US20150112153A1 (en) * 2013-10-22 2015-04-23 Neba Health, Llc System and method for a compact eeg headset
CN104586349A (zh) * 2013-10-31 2015-05-06 赖弘基 眼睛温度的测量与分析系统、接收分析装置及其方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12001086B2 (en) 2020-09-22 2024-06-04 International Business Machines Corporation Cooling system for smart contact lenses

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