WO2018028324A1 - 具有增效作用的除草组合物 - Google Patents

具有增效作用的除草组合物 Download PDF

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WO2018028324A1
WO2018028324A1 PCT/CN2017/090450 CN2017090450W WO2018028324A1 WO 2018028324 A1 WO2018028324 A1 WO 2018028324A1 CN 2017090450 W CN2017090450 W CN 2017090450W WO 2018028324 A1 WO2018028324 A1 WO 2018028324A1
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oxazolamide
active ingredient
herbicidal composition
composition
composition according
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PCT/CN2017/090450
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English (en)
French (fr)
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仲汉根
季自华
季红进
花伟
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江苏辉丰农化股份有限公司
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Publication of WO2018028324A1 publication Critical patent/WO2018028324A1/zh

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
    • A01N43/76—1,3-Oxazoles; Hydrogenated 1,3-oxazoles

Definitions

  • the invention belongs to the field of agricultural plant protection, and in particular relates to a herbicidal composition with improved properties.
  • the active ingredient diflufenican is a carotenoid biosynthesis inhibitor. Causes chlorophyll destruction and cell rupture, and plant death.
  • Pilofenapamide is an amide herbicide that is applied before and after weed germination to form an anti-leaching soil layer on the soil surface and to maintain activity throughout the growing period of the crop.
  • the penicillin can inhibit the carotenoid biosynthesis, and the content of carotenoids in the weed plants of the absorption agent decreases, causing the chlorophyll to be destroyed, and the cell membrane
  • the worm breaks the weeds show that the young shoots are discolored or white, and finally the whole plant wilted and died.
  • the active ingredient memifenap is an aryloxyphenoxypropionate herbicide. Its mechanism of action is to inhibit acetyl-CoA carboxylase, and the active ingredient needs to reach the target in the plant to exert the herbicidal effect.
  • the solvent and surfactant will act to soften the foliar layer and open the stomata of the plant, respectively, allowing the active ingredient to enter the plant.
  • the sensitive weeds showed green leaves and inhibited growth. Some weeds appeared dry and even died 2 weeks after application.
  • the purpose of the invention is to screen the herbicide containing two different weeding principles for the resistance of the herbicide in practical application and the problem of soil residue, so as to improve the control effect of the herbicide, delay the generation of the resistance, and reduce the application amount. Reduce the cost of prevention.
  • Another object of the present invention is to provide an application of the above composition for controlling weeds in the agricultural field.
  • the object of the invention can be achieved by the following measures:
  • the present invention provides a synergistic herbicidal composition
  • a synergistic herbicidal composition comprising active ingredients A and B, active ingredient A being diflufenic acid, and active ingredient B being oxazolamide.
  • the active ingredient of the composition of the present invention may contain only A and B, and may further contain other active ingredients without affecting the overall performance of the composition.
  • the weight ratio of the active ingredient of the herbicidal composition of the present invention to pyridoxal and oxazolamide is from 1:0.03 to 30.
  • the weight ratio of the active ingredient of the herbicidal composition of the present invention to diflufenic acid and oxazolamide is from 1:0.05 to 20.
  • the weight ratio of the active ingredient of the herbicidal composition of the present invention to pyridoxal and oxazolamide is from 1:0.1 to 10.
  • the weight ratio between the two components of A and B can be arbitrarily adjusted within the range of the following ratios: 1: 0.03, 1: 0.04, 1: 0.05, 1: 0.06, 1: 0.07, 1:0.08, 1:0.09, 1:0.1, 1:0.2, 1:0.3, 1:0.4, 1:0.5, 1:0.6, 1:0.7, 1:0.8, 1:0.9, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1: 14, 1:15, 1:16, 1:17, 1:18, 1:19, 1:20, 1:21, 1:22, 1:23, 1:24, 1:25, 1:26, 1:27, 1:28, 1:29, 1:30, it is also possible to select within the range of any two of the above ratios, which can be understood as a weight ratio or a molar ratio.
  • composition of the present invention can be formulated into a pesticide-acceptable dosage form together with an active ingredient and an agrochemical adjuvant.
  • the mass of the active ingredient in the composition of the present invention may be from 2 to 95%, preferably from 5 to 80%.
  • a carrier, an adjuvant and/or a surfactant may be included in the composition of the present invention.
  • Common auxiliaries can be mixed during the application.
  • Suitable auxiliaries may be solid or liquid, they are usually materials commonly used in the processing of dosage forms, such as natural or regenerated minerals, solvents, dispersants, wetting agents, adhesives, thickeners, binders or fertilizers. .
  • the method of application of the compositions of the invention comprises the use of the compositions of the invention for aerial parts of plants, in particular leaves or foliage.
  • the frequency of administration and the amount administered will depend on the biological and climatic conditions of the pathogen.
  • the plant growth site such as rice fields, may be wetted with a liquid formulation of the composition, or the composition may be applied to the soil in solid form, such as in the form of granules (soil application), the composition may be passed from the soil to the plant through the roots of the plant. In vivo (systemic action).
  • compositions may be applied only with the active ingredient (also known as the active ingredient), or with additives or The adjuvants are used in combination, and thus the composition of the present invention can be prepared into various dosage forms such as wettable powders, suspending agents, dispersible oil suspensions, aqueous emulsions, emulsifiable concentrates, water-dispersible granules and the like.
  • the compositions may be applied by spraying, misting, dusting, spreading or pouring, and the like.
  • composition of the present invention can be prepared into various dosage forms by a known method, for example, the active ingredient and an auxiliary agent such as a solvent, a solid carrier, and if necessary, can be uniformly mixed with a surfactant and ground to prepare a desired form.
  • an auxiliary agent such as a solvent, a solid carrier, and if necessary, can be uniformly mixed with a surfactant and ground to prepare a desired form.
  • the above solvent may be selected from aromatic hydrocarbons, preferably containing from 8 to 12 carbon atoms, such as a mixture of xylenes or substituted benzenes, phthalates such as dibutyl phthalate or dicaprylic acid, aliphatic hydrocarbons such as rings.
  • aromatic hydrocarbons preferably containing from 8 to 12 carbon atoms, such as a mixture of xylenes or substituted benzenes, phthalates such as dibutyl phthalate or dicaprylic acid, aliphatic hydrocarbons such as rings.
  • Alkenes or paraffins, alcohols and glycols and their ethers and esters such as ethanol, ethylene glycol, ethylene glycol monomethyl
  • ketones such as cyclohexanone
  • highly polar solvents such as N-methyl-2 Pyrrolidone, dimethyl sulfoxide or dimethylformamide
  • vegetable or vegetable oils such as soybean oil.
  • the above solid carriers are typically natural mineral fillers such as talc, kaolin, montmorillonite or activated clay.
  • a highly dispersible silicic acid or a highly dispersible adsorbent polymer carrier such as a particulate adsorbent carrier or a non-adsorbing carrier, and a suitable particulate adsorbent carrier is porous, such as pumice, bentonite or Bentonite; a suitable non-adsorbing carrier such as calcite or sand.
  • a large amount of pre-granulated materials of inorganic or organic nature can be used as a carrier, in particular dolomite.
  • Suitable surfactants are lignosulfonic acid, naphthalenesulfonic acid, phenolsulfonic acid, alkaline earth metal or amine salts, alkylarylsulfonates, alkyl groups Sulfates, alkyl sulfonates, fatty alcohol sulphates, fatty acids and sulfated fatty alcohol glycol ethers, as well as condensates of sulfonated naphthalene and naphthalene derivatives with formaldehyde, naphthalene or naphthalene sulfonic acid with phenol and formaldehyde Condensate, polyoxyethylene octyl phenyl ether, ethoxylated isooctyl phenol, octyl phenol, nonyl phenol, alkyl aryl polyglycol ether, tributyl benzene poly
  • the two active ingredients in the compositions of the present invention exhibit synergistic effects, the activity of which is more pronounced than the expected sum of activity using a single compound, and the individual activity of a single compound.
  • the synergistic effect is manifested by allowing for a reduced application rate, a broader herbicidal control profile, quicker effect, longer lasting control effect, better control of weeds by only one or a few applications, and widening of possible application intervals . These characteristics are particularly needed to control weed control practices.
  • the herbicidal composition of the invention can be applied to the control of crop weeds in the agricultural field, in particular to control rain long flower, goosegrass, crabgrass, valerian, thousand gold or valerian.
  • compositions of the present invention are mainly as follows: 1. Due to the two single doses of the present composition The chemical structure is very different, the mechanism of action is completely different, there is no cross-resistance, and the resistance problem caused by the separate use of two single agents can be delayed; 2. The composition of the invention has good safety and control effect on crops. It has been proved by experiments that the herbicide composition of the invention has stable chemical properties, remarkable synergistic effect, and exhibits obvious synergistic effect and complementary effect on the control object.
  • the active ingredient flufenic acid and the active ingredient oxazolamide are mixed well with various auxiliaries and fillers, and pulverized by an ultrafine pulverizer to obtain a wettable powder.
  • Example 2 42% flufenacetate oxazolamide wettable powder
  • the active ingredient flufenic acid and oxazolamide, auxiliary agent and filler are uniformly mixed according to the formula, pulverized into a wettable powder by air flow, and then added with a certain amount of water, mixed and extruded, granulated, and sieved by drying. A water dispersible granule product is obtained afterwards.
  • Example 4 11% flufenacetate oxazolamide water dispersible granules
  • Example 5 20% flufenacetate oxazolamide water dispersible granules
  • Example 6 31% flufenacetate oxazolamide water dispersible granules
  • the active ingredient pyripramine and oxazolamide, an emulsifier, an organic solvent and the like are uniformly mixed in a ratio of the formulation to obtain a finished product.
  • Example 8 11% flufenacetate oxazolamide emulsifiable concentrate
  • the disease index and control effect were calculated.
  • the control effect is converted into the probability value (y)
  • the concentration of the drug solution ( ⁇ g/ml) is converted into the logarithm value (x)
  • the virulence equation is calculated by the least squares method and the concentration EC50 is suppressed
  • the virulence index of the drug is calculated according to the method of Sun Yunpei. Grade Co-toxicity coefficient (CTC).
  • CTC Grade Co-toxicity coefficient
  • Measured virulence index (ATI) (standard drug EC50 / test drug EC50) * 100
  • Theoretical virulence index (TTI) A virulence index * Percentage of A in the mixture + B virulence index * Percentage of B in the mixture
  • CTC Co-toxicity coefficient [mixture measured virulence index (ATI) / mixed theory virulence index (TTI)] * 100
  • CTC ⁇ 80 the composition showed antagonism, 80 ⁇ CTC ⁇ 120, the composition showed an additive effect, CTC ⁇ 120, and the composition showed synergistic effect.

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

提供一种具有增效作用的除草组合物，该组合物中含有有效成分吡氟酰草胺和噁唑酰草胺，有效成分吡氟酰草胺和噁唑酰草胺的重量比为1：0.03～30。药效试验表明，该组合物具有互补性强、增效作用明显、杀草谱扩大、施用量减少、施药适期延长、对作物安全性高、环境污染降低、与环境兼容性强等积极特点。

Description

具有增效作用的除草组合物 技术领域
本发明属于农业植物保护领域，特别是涉及一种具有改进性能的除草组合物。
背景技术
活性组分吡氟酰草胺(diflufenican)该药属于类胡萝卜素生物合成抑制剂。导致叶绿素破坏及细胞破裂，植物死亡。吡氟酰草胺是一种酰胺类除草剂，在杂草发芽前后施用可在土表形成抗淋溶的药土层，在作物整个生长期保持活性。当杂草萌发通过药土层幼芽或根系均能吸收药剂，吡氟酰草胺具有抑制类胡萝卜素生物合成作用，吸收药剂的杂草植株中类胡萝卜素含量下降，导致叶绿素被破坏，细胞膜破裂，杂草则表现为幼芽脱色或白色，最后整株萎蔫死亡。
活性组分噁唑酰草胺(metamifop)属于芳氧苯氧基丙酸酯类除草剂。其作用机理是抑制乙酰辅酶A羧化酶，有效成份需要达到植物体内靶标方能发挥杀草作用。溶剂和表面活性剂将分别起到软化叶面腊质层和打开植物气孔的作用，使有效成份进入植物体内发挥作用。用药后几天内敏感杂草出现叶面退绿，抑制生长，有些杂草在施药后2周出现干枯，甚至死亡。
实际的农药经验已经表明，重复且专一施用一种活性化合物来防治杂草在很多情况下将导致杂草的快速选择性，目前通常使用不同活性化合物的混合物来防治有害杂草。通过将具有不同作用机理的活性化合物进行组合，可延缓抗性产生，降低施用量，减少防治成本。
发明内容
本发明的目的是针对除草剂在实际应用中抗性以及土壤残留问题，筛选出含有两种不同除草原理的除草剂进行复配，以提高除草剂防治效果，延缓抗性产生，降低施用量，减少防治成本。
本发明的另一目的是提供一种上述组合物在农业领域防治杂草的应用。
本发明的目的可以通过以下措施达到：
本发明提供了一种具有增效作用的除草组合物，该组合物中含有有效成分A和B，有效成分A为吡氟酰草胺，有效成分B为噁唑酰草胺。
发明人通过试验发现，上述除草组合物增效明显，更重要的是施用量减少，降低使用成本。含有组分A与组分B的化合物结构类型不同，作用机制各异，两者复配能够扩大除草谱，并且可以在一定程度上延缓杂草抗性的产生和发展速度，且组分A与组分B之间无交互抗性。
本发明组合物的有效成分可以只包含A和B，也可以在不影响组合物整体性能的基础上，进一步包含其他有效成分。
在一种方案中，本发明除草组合物的有效成分吡氟酰草胺和噁唑酰草胺的重量比为1：0.03～30。
在另一种方案中，本发明除草组合物的有效成分吡氟酰草胺和噁唑酰草胺的重量比为1：0.05～20。
在另一种方案中，本发明除草组合物的有效成分吡氟酰草胺和噁唑酰草胺的重量比为1：0.1～10。
在一种优选的方案中，A和B两组分之间的重量比可以任意地在下述配比的范围内进行调整：1：0.03、1：0.04、1：0.05、1：0.06、1：0.07、1：0.08、1：0.09、1：0.1、1：0.2、1：0.3、1：0.4、1：0.5、1：0.6、1：0.7、1：0.8、1：0.9、1：1、1：2、1：3、1：4、1：5、1：6、1：7、1：8、1：9、1：10、1：11、1：12、1：13、1：14、1：15、1：16、1：17、1：18、1：19、1：20、1：21、1：22、1：23、1：24、1：25、1：26、1：27、1：28、1：29、1：30，也可以在以上任意两个配比所组成的范围内进行选择，这些比例可以理解为重量比，也可以包括摩尔比。
本发明的组合物可以由有效成分与农药助剂共同制成农药上可接受的剂型。
本发明的组合物中有效成分的质量含量可以为2～95％，优选5～80％。
本发明组合物中可以包含载体、助剂和/或表面活性剂。在施用的过程中可以混合常用的助剂。
合适的助剂可以是固体或液体，它们通常是剂型加工过程中常用的物质，例如天然的或再生的矿物质，溶剂、分散剂、润湿剂、胶粘剂、增稠剂、粘合剂或肥料。
本发明组合物的施用方法包括将本发明的组合物用于植物生长的地上部分，特别是叶部或叶面。施用的频率和施用量取决于病原体的生物学和气候生存条件。可以将植物的生长场所，如稻田，用组合物的液体制剂浸湿，或者将组合物以固体形式施用于土壤中，如以颗粒形式(土壤施用)，组合物可以由土壤经植物根部进入植物体内(内吸作用)。
这些组合物可以仅仅包含活性成分(又称有效成分)进行施用，也可以与添加剂或 助剂一起混合使用，因此本发明的组合物可以制备成各种剂型，例如可湿性粉剂、悬浮剂、可分散油悬浮剂、水乳剂、乳油、水分散粒剂等。根据这些组合物的性质以及施用组合物所要达到的目的和环境情况，可以选择将组合物以喷雾、弥雾、喷粉、撒播或泼浇等之类的方法施用。
可用已知的方法可以将本发明的组合物制备成各种剂型，如可以将有效成分与助剂，如溶剂、固体载体，需要时可以与表面活性剂一起均匀混合、研磨，制备成所需要的剂型。
上述的溶剂可选自芳香烃，优选含8-12个碳原子，如二甲苯混合物或取代的苯，酞酸酯类，如酞酸二丁酯或酞酸二辛酸，脂肪烃类，如环已烷或石蜡，醇和乙二醇和它们的醚和酯，如乙醇，乙二醇，乙二醇单甲基；酮类，如环已酮，强极性的溶剂，如N-甲基-2-吡咯烷酮，二甲基亚砜或二甲基甲酰胺，和植物油或植物油，如大豆油。
上述的固体载体，如用于粉剂和可分散剂的通常是天然矿物填料，例如滑石、高岭土，蒙脱石或活性白土。为了管理组合物的物理性能，也可以加入高分散性硅酸或高分散性吸附聚合物载体，例如粒状吸附载体或非吸附载体，合适的粒状吸附载体是多孔型的，如浮石、皂土或膨润土；合适的非吸附载体如方解石或砂。另外，可以使用大量的无机性质或有机性质的预制成粒状的材料作为载体，特别是白云石。
根据本发明的组合物中的有效成分的化学性质，合适的表面活性剂为木质素磺酸、萘磺酸、苯酚磺酸、碱土金属盐或胺盐，烷基芳基磺酸盐，烷基硫酸盐，烷基磺酸盐，脂肪醇硫酸盐，脂肪酸和硫酸化脂肪醇乙二醇醚，还有磺化萘和萘衍生物与甲醛的缩合物，萘或萘磺酸与苯酚和甲醛的缩合物，聚氧乙烯辛基苯基醚，乙氧基化异辛基酚，辛基酚，壬基酚，烷基芳基聚乙二醇醚，三丁基苯聚乙二醇醚，三硬脂基苯基聚乙二醇醚，烷基芳基聚醚醇，乙氧基化蓖麻油，聚氧乙烯烷基醚，氧化乙烯缩合物、乙氧基化聚氧丙烯，月桂酸聚乙二醇醚缩醛，山梨醇酯，木质素亚硫酸盐废液和甲基纤维素。
本发明的组合物中两种有效成分表现为增效效果，该组合物的活性比使用单个化合物的活性预期总和，以及单个化合物的单独活性更为显著。增效效果表现为允许施用量减少、更宽的除草控制谱、见效快、更持久的防治效果、通过仅仅一次或少数几次施用更好的控制杂草、以及加宽了可能的施用间隔时间。这些特性是防除控制杂草实践过程中特别需要的。
本发明的除草组合物可应用在农业领域防治农作物杂草方面，特别是防治雨久花、牛筋草、马唐、稗草、千金子或菵草。
本发明的除草组合物的表现出的其它特点主要表现为：1、由于本组合物的两个单剂 化学结构差异很大，作用机理完全不同，不存在交互抗性，可延缓两个单剂单独使用所产生的抗性问题；2、本发明的组合物对作物安全、防效好。经试验证明，本发明除草剂组合物化学性质稳定，增效显著，对防治对象表现出明显的增效以及互补作用。
具体实施方式
为了使本发明的目的、技术方案及优点更加清楚明白，以下结合实施例，对本发明进行进一步详细说明。应当理解，此处所描述的具体实施例仅用以解释本发明，并不用于限定本发明，凡在本发明的精神和原则之内所做的任何修改、等同替换和改进等，均应包含在本发明的保护范围之内。
以下实施例所有配方中百分比均为重量百分比。本发明组合物各种制剂的加工工艺均为现有技术，根据不同情况可以有所变化。
一、剂型制备实施例
(一)可湿性粉剂的加工及实施例
将活性成分吡氟酰草胺与活性成分噁唑酰草胺与各种助剂及填料等按比例充分混合，经超细粉碎机粉碎后制得可湿性粉剂。
实施例1:10.5％吡氟酰草胺·噁唑酰草胺可湿性粉剂
吡氟酰草胺0.5％，噁唑酰草胺10％，白炭黑3％，烷基芳基磺酸盐4％，膨润土3％，高岭土补足至100％。
实施例2:42％吡氟酰草胺·噁唑酰草胺可湿性粉剂
吡氟酰草胺40％，噁唑酰草胺2％，磺酸钠3％，木质素磺酸钾3％，高岭土5％，白炭黑补足至100％。
实施例3:84％吡氟酰草胺·噁唑酰草胺可湿性粉剂
吡氟酰草胺14％，噁唑酰草胺70％，方解石4％，脂肪醇硫酸盐5％，高岭土5％，轻质碳酸钙补足至100％。
(二)水分散粒剂的加工及实施例
将活性成分吡氟酰草胺与噁唑酰草胺、助剂和填料按配方的比例混合均匀，经气流粉碎成可湿性粉剂，再加入一定量的水混合挤压造粒，经干燥筛分后制得水分散粒剂产品。
实施例4：11％吡氟酰草胺·噁唑酰草胺水分散粒剂
吡氟酰草胺1％，噁唑酰草胺10％，十二烷基硫酸钠5％，芳基烷基磺酸钠3％,脂肪硫醇酸铵4％，高岭土补足至100％。
实施例5：20％吡氟酰草胺·噁唑酰草胺水分散粒剂
吡氟酰草胺10％，噁唑酰草胺10％，十二烷基磺酸钾5％，聚氧乙烯辛基苯基醚4％，木质素磺酸钠4％,硅藻土补足至100％。
实施例6：31％吡氟酰草胺·噁唑酰草胺水分散粒剂
吡氟酰草胺30％，噁唑酰草胺1％，十二烷基硫酸钾3％，脂肪酸和硫酸化脂肪醇乙二醇醚4％，木质素磺酸钠5％,木质素碳酸钙补足至100％。
(三)乳油的加工及实施例
将活性成分吡氟酰草胺与噁唑酰草胺、乳化剂、有机溶剂等各组分按配方的比例混合均匀即得成品。
实施例7：15.5％吡氟酰草胺·噁唑酰草胺乳油
吡氟酰草胺0.5％，噁唑酰草胺15％，烷基芳基聚乙二醇醚10％,甲苯补足至100％。
实施例8：11％吡氟酰草胺·噁唑酰草胺乳油
吡氟酰草胺10％，噁唑酰草胺1％，乙氧基化聚氧丙烯8％，二甲苯补足至100％。
实施例9：24％吡氟酰草胺·噁唑酰草胺乳油
吡氟酰草胺20％，噁唑酰草胺4％，三丁基苯聚乙二醇醚12％，甲苯补足至100％。
二、药效验证试验
(一)生物测定实施例
以吡氟酰草胺作为标准药剂，计算病情指数和防治效果。将防治效果换算成几率值(y)，药液浓度(μg/ml)转换成对数值(x)，以最小二乘法计算毒力方程和抑制中浓度EC50，依孙云沛法计算药剂的毒力指数级共毒系数(CTC)。毒力测定结果见表1。
实测毒力指数(ATI)＝(标准药剂EC50/供试药剂EC50)*100
理论毒力指数(TTI)＝A药剂毒力指数*混剂中A的百分含量+B药剂毒力指数*混剂中B的百分含量
共毒系数(CTC)＝[混剂实测毒力指数(ATI)/混剂理论毒力指数(TTI)]*100
CTC≤80,组合物表现为拮抗作用,80＜CTC＜120，组合物表现为相加作用,CTC≥120，组合物表现为增效作用。
1、吡氟酰草胺与噁唑酰草胺复配对雨久花的毒力测定试验
表1吡氟酰草胺与噁唑酰草胺不同配比复配对雨久花的毒力测定分析(一)
Figure PCTCN2017090450-appb-000001
Figure PCTCN2017090450-appb-000002
结果(表1)表明，吡氟酰草胺与噁唑酰草胺在配比1～30：1～30之间，共毒系数均在125以上，说明吡氟酰草胺与噁唑酰草胺复配对雨久花的防除具有显著的协同增效作用。实验发现，当吡氟酰草胺与噁唑酰草胺不在本发明的配方范围时，对雨久花很难起到协同增效作用。
2、吡氟酰草胺与噁唑酰草胺复配对稗草的毒力测定试验(二)
表2吡氟酰草胺与噁唑酰草胺复配对稗草的毒力测定结果分析
Figure PCTCN2017090450-appb-000003
结果(表2)表明，吡氟酰草胺与噁唑酰草胺在配比1～30：1～30之间，共毒系数均在135以上，说明吡氟酰草胺与噁唑酰草胺复配对稗草的防除具有显著的协同增效作用。实验发现，当吡氟酰草胺与噁唑酰草胺不在本发明的配方范围时，对稗草很难起到协同增效作用。
(二)田间药效试验
1、利用本发明制得的实施例来验证吡氟酰草胺与噁唑酰草胺的田间防治效果。
Figure PCTCN2017090450-appb-000004
预期防效(％)＝X+Y-XY/100(其中，X，Y为单剂防效)
表3.吡氟酰草胺与噁唑酰草胺复配对千金子和菵草的田间防效试验结果
Figure PCTCN2017090450-appb-000005
Figure PCTCN2017090450-appb-000006
Figure PCTCN2017090450-appb-000007
测定结果(表3)表明，吡氟酰草胺与噁唑酰草胺复配对防治杂草千金子和菵草的防效明显提高，说明二者复配对杂千金子和菵草有显著的协同增效作用。

Claims (10)

  1. 一种具有增效作用的除草组合物，其特征在于该组合物中含有有效成分吡氟酰草胺和噁唑酰草胺。
  2. 根据权利要求1所述的除草组合物，其特征在于所述有效成分吡氟酰草胺和噁唑酰草胺的重量比为1：0.03～30。
  3. 根据权利要求2所述的除草组合物，其特征在于所述有效成分吡氟酰草胺和噁唑酰草胺的重量比为1：0.05～20。
  4. 根据权利要求3所述的除草组合物，其特征在于所述有效成分吡氟酰草胺和噁唑酰草胺的重量比为1：0.1～10。
  5. 根据权利要求1所述的除草组合物，其特征在于该组合物由有效成分与农药助剂共同制成农药上可接受的剂型。
  6. 根据权利要求5所述的除草组合物，其特征在于该组合物中有效成分的质量含量为2～95％。
  7. 根据权利要求6所述的除草组合物，其特征在于该组合物中有效成分的质量含量为5～80％。
  8. 根据权利要求5所述的除草组合物，其特征在于所述剂型为可湿性粉剂、水分散粒剂或乳油。
  9. 权利要求1所述的除草组合物在农业领域防治农作物杂草方面的用途。
  10. 根据权利要求9所述的用途，其特征在于所述杂草选自雨久花、稗草、牛筋草、马唐、千金子或菵草。
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