WO2018028221A1 - Dispositif portable pour aider à la récupération de patients atteints de maladie de parkinson - Google Patents

Dispositif portable pour aider à la récupération de patients atteints de maladie de parkinson Download PDF

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Publication number
WO2018028221A1
WO2018028221A1 PCT/CN2017/079362 CN2017079362W WO2018028221A1 WO 2018028221 A1 WO2018028221 A1 WO 2018028221A1 CN 2017079362 W CN2017079362 W CN 2017079362W WO 2018028221 A1 WO2018028221 A1 WO 2018028221A1
Authority
WO
WIPO (PCT)
Prior art keywords
parkinson
disease
wearable device
patients
circuit board
Prior art date
Application number
PCT/CN2017/079362
Other languages
English (en)
Chinese (zh)
Inventor
张贯京
高伟明
Original Assignee
深圳市前海安测信息技术有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳市前海安测信息技术有限公司 filed Critical 深圳市前海安测信息技术有限公司
Publication of WO2018028221A1 publication Critical patent/WO2018028221A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation

Definitions

  • Wearable device for assisting rehabilitation of patients with Parkinson's disease
  • the present invention relates to the field of health care, and more particularly to a wearable device for assisting rehabilitation of a patient with Parkinson's disease.
  • Parkinson's Disease also known as tremor paralysis syndrome.
  • Parkinson's syndrome is a chronic degenerative disorder of the central nervous system. According to statistics, there are currently about 5 million patients with Parkinson's disease worldwide. With the growing problem of old age in China, Parkinson's disease has seriously threatened the health of middle-aged and elderly people in China. Patients with Parkinson's disease usually have varying degrees of dyskinesia symptoms, clinically characterized by resting tremor, bradykinesia, muscle stiffness, and posture gait disorders. The resting tremor of Parkinson's patients is due to the multiple contraction movements of the upper limbs to the antagonist muscles.
  • the tremor frequency is generally between 3 Hz and 9 Hz, and the tremor signal source is located in the neuronal activity network of the cerebral cortex.
  • the occurrence of resting tremor in the upper limb not only affects the patient's physical posture, but also has a greater negative effect on the patient's daily living ability and quality of life.
  • the active activity of the upper limbs is decreased, the body discomfort, daily activities are limited, and emotional communication is performed. And cognitive impairments, etc.
  • the treatment of Parkinson's disease is divided into drug therapy and physical therapy. Although drug therapy is currently the mainstream treatment, the risk of misdiagnosis and drug side effects is also present. Although physical therapy is a better method, it is lacking.
  • the main object of the present invention is to provide a wearable device for assisting the rehabilitation of patients with Parkinson's disease, aiming at solving the problem of how to assist rehabilitation patients in Parkinson's disease.
  • the present invention provides a wearable device for assisting rehabilitation of a patient with Parkinson's disease, the wearable device comprising a flexible circuit board, and a wristband and a finger are respectively connected at two ends of the flexible circuit board.
  • the flexible circuit board is provided with an infrared detector, an infrared laser, an inertial sensor, a communication interface, and a microcontroller, wherein the infrared detector, the infrared laser, the inertial sensor, and the communication interface are electrically connected to the micro control
  • a pulse electrode is disposed on the wristband, and the pulse electrode is electrically connected to the microcontroller, wherein:
  • the infrared detector is used to detect the position of a target item around a patient with Parkinson's disease
  • the infrared laser is used to emit an infrared vision aperture to illuminate the position of the target item
  • the pulse electrode is used to generate an electrical stimulation pulse transmitted to the phrenic nerve of the hand of a patient with Parkinson's disease;
  • the inertial sensor is configured to sense tremor data of a hand of a Parkinson's disease patient, and send tremor data of a hand of a Parkinson's disease patient to the microcontroller;
  • the microcontroller is configured to send tremor data of a hand of a Parkinson's disease patient to the health management platform of the medical health center through the communication interface.
  • the wristband is a retractable elastic wristband for wearing on the wrist of a patient with Parkinson's disease.
  • the finger hook is a J-shaped curved structure, and the curved section of the finger hook is hooked in the finger slit of the Parkinson's disease patient.
  • the outer portion of the flexible circuit board is covered with a casing made of a flexible waterproof material.
  • a connecting strap is disposed between the flexible circuit board and the wristband, and the connecting strap is a flexible strap.
  • the flexible circuit board is provided with a voice player connected to the microcontroller, and the voice player is used for playing a rehabilitation training instruction of a patient with Parkinson's disease and taking a medication.
  • the inertial sensor is a six-axis inertial sensor, and the six-axis inertial sensor comprises a three-axis gyroscope and a three-axis acceleration sensor.
  • the inertial sensor is a nine-axis inertial sensor including a three-axis gyroscope, a three-axis acceleration sensor, and a three-axis magnetic induction sensor.
  • the flexible circuit board is further provided with a micro battery for providing working power for the wearable device.
  • the flexible circuit board is further provided with a charging port, and the charging port is connected to the micro battery for plugging an external power source to charge the micro battery.
  • the wearable device for assisting the rehabilitation of patients with Parkinson's disease adopts the above technical solution, and achieves the following technical effects: guiding the patients with Parkinson's disease to discover the target through visual stimulation The article, thereby assisting the patient with Parkinson's disease to visually recognize the target item; generating an electrical stimulation pulse through the pulse electrode to the phrenic nerve of the patient's hand to suppress resting tremor of the patient's hand, thereby reducing the upper limb of the hand tremor
  • the inconvenience of exercise can increase the initiative of upper limb activity in patients with Parkinson's disease.
  • the tremor data of the hand of Parkinson's disease patient is sent to the health management platform through the communication interface, so as to provide a basis for doctors to carry out rehabilitation treatment for patients with Parkinson's disease, thereby achieving the effect of assisting the rehabilitation of patients with Parkinson's disease.
  • FIG. 1 is a schematic structural view of a preferred embodiment of a wearable device for assisting rehabilitation of a patient with Parkinson's disease according to the present invention
  • FIG. 2 is a circuit connection diagram of a preferred embodiment of a wearable device for assisting rehabilitation of a patient with Parkinson's disease.
  • FIG. 1 is a schematic structural view of a preferred embodiment of a wearable device for assisting rehabilitation of a patient with Parkinson's disease
  • FIG. 2 is a view of the present invention for assisting patients with Parkinson's disease.
  • the wearable device comprises a flexible circuit board 1 , and the wristband 2 and the finger hook 3 are respectively connected at two ends of the flexible circuit board 1 .
  • the flexible circuit board 1 is worn on the back of the patient's hand
  • the wristband 2 is worn on the wrist of the patient
  • the finger hook 3 is a J-shaped curved structure
  • the curved section of the finger hook 3 is hooked on the patient
  • the fingers are sewn inside.
  • the structure of the wearable device of the present embodiment does not restrict the action of the patient, does not hinder the free movement of the patient, and avoids interfering with the normal life of the patient with Parkinson's disease.
  • the wristband 2 is a retractable elastic wristband made of an elastic fabric to accommodate variations in the diameter of the wrist of different patients.
  • the outer surface of the flexible circuit board 1 is covered with a casing made of a flexible waterproof material, which can prevent the device from entering water, prevent the flexible circuit board 1 from rubbing the skin of the back of the hand, and prevent the flexible circuit board 1 from being damaged by the collision of foreign objects.
  • the flexible circuit board 1 is provided with an infrared detector 11, an infrared laser 12, a inertial sensor 13, a microcontroller 14, a communication interface 15, and a voice player 16.
  • the infrared detector 11, the infrared laser 12, the inertial sensor 13, the communication interface 15 and the voice player 16 are all electrically connected to the microcontroller 14.
  • the infrared detector 11 is an existing sensor for detecting an object by emitting infrared rays for detecting the position of a target item around a patient of Parkinson's disease by emitting infrared rays.
  • the target item is a household item that is often used in a patient's life, including but not limited to, tableware, teacups, clothes, shoes, socks, glasses, and the like.
  • the infrared laser 12 is a conventional micro-infrared laser generating device for emitting an infrared visual aperture and illuminating the position of the target object to visually stimulate the patient to discover the target object. Thereby assisting in improving the visual cognition of the target item in patients with Parkinson's disease.
  • the inertial sensor 13 may be a six-axis inertial sensor including a three-axis inertial sensor including a three-axis gyroscope and a three-axis acceleration sensor, and a three-axis inertial sensor including a three-axis gyroscope and three-axis Acceleration sensor and three-axis magnetic induction sensor.
  • the inertial sensor 13 is used for collecting tremor data of the hand inertial motion of a patient with Parkinson's disease, including data such as tremor direction, tremor amplitude, and tremor frequency in three directions of the X-axis, the y-axis, and the z-axis, and the Parkinson's disease.
  • the tremor data of the patient's hand is sent to the microcontroller 14.
  • the microcontroller 14 may be a micro control chip, a data processing chip or an information processing unit having a data processing function.
  • the communication interface 15 is a communication port supporting a wireless transmission network such as Bluetooth or WiFi or a remote transmission network, and is used for transmitting the tremor data of the hand of the Parkinson's disease patient to the health management platform of the medical health center.
  • the microcontroller 14 transmits the tremor data of the hand of the Parkinson's disease patient to the health management platform of the medical health center through the communication interface 15 for the doctor to pay for Parkin Patients with Mori disease provide a basis for rehabilitation.
  • the voice player 16 uses a conventional pair of conventional voice recorders for playing the patient's rehabilitation training instructions, which is convenient for the upper limb rehabilitation training performed by the patient.
  • the voice player 16 is also used to play the patient's medication time to remind the patient to take the medicine according to the medicine, thereby effectively preventing the patient from forgetting to take the medicine according to the medicine, and is beneficial to the rehabilitation of the Parkinson's disease patient.
  • the wristband 2 is provided with a pulse electrode 21, which is electrically connected to the microcontroller 14.
  • the pulse electrode 21 is attached to the muscle abdomen surface of the hand muscle, and the hand muscle may be a wrist extensor or a wrist flexor.
  • the pulse electrodes 21 may be one or more, which may be attached to the sacral nerve of the hand of a Parkinson's disease patient.
  • the pulse electrode 21 is used to generate an electrical stimulation pulse under the microcontroller 14 to transmit the phrenic nerve to the patient's hand to suppress the patient's hand tremor, thereby reducing the influence of hand tremor on the inconvenience of upper limb movement, thereby increasing The initiative of upper limb activity in patients with Parkinson's disease, and thus the rehabilitation of patients with Parkinson's disease.
  • the pulse electrode 21 generates an electrical stimulation pulse that inhibits Parkinson's resting tremor and transmits it to the sacral nerve of the patient's hand, and inhibits the central tremor signal transmission by electrically stimulating the phrenic nerve to inhibit the activity of the spinal cord inner neuron. a pathway of motor neurons, thereby suppressing the tremor signal transmitted to the hand muscles, and ultimately inhibiting resting tremor in patients with Parkinson's disease.
  • connection belt 4 is disposed between the flexible circuit board 1 and the wristband 2, and the connection belt 4 is a flexible belt.
  • the structure can flexibly connect the flexible circuit board 1 to the wristband 2. In order to minimize the impact of the flexible circuit board 1 on the patient's hand flexibility.
  • the flexible circuit board 1 is further provided with a micro battery 17 and a charging port 18 for providing working power for the wearable device, and the micro battery 17 is a low radiation, low power consumption. Rechargeable lithium battery or button battery, it will not affect the health of patients.
  • the charging port 18 is electrically connected to the micro battery 17.
  • the charging port 18 can be a USB interface or other standard battery charging interface.
  • the charging port 18 can be directly inserted into an external power source (such as a computer USB interface or a low voltage regulator).
  • the micro battery 17 is charged, for example.
  • the wearable device for assisting rehabilitation of a Parkinson's disease patient is worn on the patient's hand due to its quality relative to the wearable and glove-like motion urging system.
  • the wearable device for assisting rehabilitation of patients with Parkinson's disease through visual stimulation, guides patients with Parkinson's disease to find target items, thereby assisting patients with Parkinson's disease to visually recognize the target items;
  • the pulse electrode generates an electrical stimulation pulse to the phrenic nerve of the patient's hand to inhibit resting tremor in the patient's hand, thereby reducing the impact of hand tremor on the inconvenience of upper limb movement, and increasing the initiative of upper limb activity in patients with Parkinson's disease;
  • the tremor data of the hand of Parkinson's disease patient is sent to the health management platform through the communication interface, so as to provide a basis for the doctor to carry out rehabilitation treatment for patients with Parkinson's disease, thereby achieving the effect of assisting the rehabilitation of patients with Parkinson's disease.
  • the wearable device for assisting rehabilitation of Parkinson's disease patients adopts the above technical solution, and achieves the following technical effects: guiding the patients with Parkinson's disease to discover the target through visual stimulation The article, thereby assisting the patient with Parkinson's disease to visually recognize the target item; generating an electrical stimulation pulse through the pulse electrode to the phrenic nerve of the patient's hand to suppress resting tremor of the patient's hand, thereby reducing the upper limb of the hand tremor
  • the inconvenience of exercise can increase the initiative of upper limb activity in patients with Parkinson's disease.
  • the tremor data of the hand of Parkinson's disease patients is sent to the health management platform through the communication interface, so as to provide a basis for doctors to carry out rehabilitation treatment for patients with Parkinson's disease, thereby achieving the effect of assisting the rehabilitation of patients with Parkinson's disease.

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  • Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
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  • Molecular Biology (AREA)
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  • Radiology & Medical Imaging (AREA)
  • Rehabilitation Tools (AREA)

Abstract

L'invention concerne un dispositif portable pour aider à la récupération de patients atteints de la maladie de parkinson, comprenant une carte de circuit imprimé souple (1), deux extrémités de la carte de circuit souple (1) étant respectivement reliées à un bracelet (2) et à un crochet de doigt (3). La carte de circuit souple (1) est pourvue d'un détecteur infrarouge (11), d'un laser infrarouge (12), d'un capteur inertiel (13), d'une interface de communication (15) et d'un microcontrôleur (14); le détecteur infrarouge (11), le laser infrarouge (12), le capteur inertiel (13) et l'interface de communication (15) sont tous connectés électriquement au microcontrôleur (14). Une électrode à impulsions (21) est disposée sur le bracelet (2), et l'électrode à impulsions (21) est électriquement connectée au microcontrôleur (14). Le dispositif portable peut réduire l'impact de mouvements d'extrémité supérieurs gênants provoqués par des tremblements de main chez des patients atteints de la maladie de Parkinson. Ainsi, les patients prennent plus d'initiative pour déplacer leurs bras, ce qui fournit la base pour les médecins de la réalisation d'un traitement de récupération pour des patients atteints de la maladie de Parkinson, de façon à obtenir l'effet d'assistance à la récupération de patients atteints de la maladie de Parkinson.
PCT/CN2017/079362 2016-08-06 2017-04-01 Dispositif portable pour aider à la récupération de patients atteints de maladie de parkinson WO2018028221A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201620847380.7 2016-08-06
CN201620847380.7U CN206424425U (zh) 2016-08-06 2016-08-06 用于辅助帕金森病患者康复的可穿戴设备

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WO2018028221A1 true WO2018028221A1 (fr) 2018-02-15

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Cited By (11)

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Publication number Priority date Publication date Assignee Title
CN108968918A (zh) * 2018-06-28 2018-12-11 北京航空航天大学 早期帕金森的可穿戴辅助筛查设备
US10173060B2 (en) 2014-06-02 2019-01-08 Cala Health, Inc. Methods for peripheral nerve stimulation
US10625074B2 (en) 2013-01-21 2020-04-21 Cala Health, Inc. Devices and methods for controlling tremor
US10765856B2 (en) 2015-06-10 2020-09-08 Cala Health, Inc. Systems and methods for peripheral nerve stimulation to treat tremor with detachable therapy and monitoring units
US10814130B2 (en) 2016-07-08 2020-10-27 Cala Health, Inc. Dry electrodes for transcutaneous nerve stimulation
DE202020105401U1 (de) 2020-09-21 2022-01-07 Boll & Kirch Filterbau Gesellschaft mit beschränkter Haftung Filtrationssystem für die Ölfiltration insbesondere für Schiffsaggregate wie Schiffsmotoren
US11331480B2 (en) 2017-04-03 2022-05-17 Cala Health, Inc. Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
US11344722B2 (en) 2016-01-21 2022-05-31 Cala Health, Inc. Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
US11596785B2 (en) 2015-09-23 2023-03-07 Cala Health, Inc. Systems and methods for peripheral nerve stimulation in the finger or hand to treat hand tremors
US11857778B2 (en) 2018-01-17 2024-01-02 Cala Health, Inc. Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation
US11890468B1 (en) 2019-10-03 2024-02-06 Cala Health, Inc. Neurostimulation systems with event pattern detection and classification

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US11839583B1 (en) 2018-09-11 2023-12-12 Encora, Inc. Apparatus and method for reduction of neurological movement disorder symptoms using wearable device
US11701293B2 (en) 2018-09-11 2023-07-18 Encora, Inc. Apparatus and method for reduction of neurological movement disorder symptoms using wearable device
CN113082531A (zh) * 2021-04-28 2021-07-09 陈仲钱 一种新型手背穴位毫米波扫描治疗方法
WO2024167465A1 (fr) * 2023-02-09 2024-08-15 Agency For Science, Technology And Research Dispositif et procédé de mesure externe de flux sanguin

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CN105142714A (zh) * 2013-01-21 2015-12-09 卡拉健康公司 用于控制震颤的设备和方法
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Cited By (19)

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Publication number Priority date Publication date Assignee Title
US10625074B2 (en) 2013-01-21 2020-04-21 Cala Health, Inc. Devices and methods for controlling tremor
US10905879B2 (en) 2014-06-02 2021-02-02 Cala Health, Inc. Methods for peripheral nerve stimulation
US12109413B2 (en) 2014-06-02 2024-10-08 Cala Health, Inc. Systems and methods for peripheral nerve stimulation to treat tremor
US10960207B2 (en) 2014-06-02 2021-03-30 Cala Health, Inc. Systems for peripheral nerve stimulation
US10561839B2 (en) 2014-06-02 2020-02-18 Cala Health, Inc. Systems for peripheral nerve stimulation
US10173060B2 (en) 2014-06-02 2019-01-08 Cala Health, Inc. Methods for peripheral nerve stimulation
US10179238B2 (en) 2014-06-02 2019-01-15 Cala Health, Inc. Systems for peripheral nerve stimulation
US10549093B2 (en) 2014-06-02 2020-02-04 Cala Health, Inc. Method for peripheral nerve stimulation
US10765856B2 (en) 2015-06-10 2020-09-08 Cala Health, Inc. Systems and methods for peripheral nerve stimulation to treat tremor with detachable therapy and monitoring units
US11596785B2 (en) 2015-09-23 2023-03-07 Cala Health, Inc. Systems and methods for peripheral nerve stimulation in the finger or hand to treat hand tremors
US11344722B2 (en) 2016-01-21 2022-05-31 Cala Health, Inc. Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
US11918806B2 (en) 2016-01-21 2024-03-05 Cala Health, Inc. Systems, methods and devices for peripheral neuromodulation of the leg
US10814130B2 (en) 2016-07-08 2020-10-27 Cala Health, Inc. Dry electrodes for transcutaneous nerve stimulation
US11331480B2 (en) 2017-04-03 2022-05-17 Cala Health, Inc. Systems, methods and devices for peripheral neuromodulation for treating diseases related to overactive bladder
US11857778B2 (en) 2018-01-17 2024-01-02 Cala Health, Inc. Systems and methods for treating inflammatory bowel disease through peripheral nerve stimulation
CN108968918A (zh) * 2018-06-28 2018-12-11 北京航空航天大学 早期帕金森的可穿戴辅助筛查设备
US11890468B1 (en) 2019-10-03 2024-02-06 Cala Health, Inc. Neurostimulation systems with event pattern detection and classification
WO2022058975A1 (fr) 2020-09-21 2022-03-24 Boll & Kirch Filterbau Gesellschaft Mit Beschraenkter Haftung Système de filtration pour filtration d'huile, en particulier pour des unités marines telles que des moteurs marins
DE202020105401U1 (de) 2020-09-21 2022-01-07 Boll & Kirch Filterbau Gesellschaft mit beschränkter Haftung Filtrationssystem für die Ölfiltration insbesondere für Schiffsaggregate wie Schiffsmotoren

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