WO2018018352A1 - Synchronous display, positioning and demarcation method and device for multiple contrast images - Google Patents

Synchronous display, positioning and demarcation method and device for multiple contrast images Download PDF

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Publication number
WO2018018352A1
WO2018018352A1 PCT/CN2016/091525 CN2016091525W WO2018018352A1 WO 2018018352 A1 WO2018018352 A1 WO 2018018352A1 CN 2016091525 W CN2016091525 W CN 2016091525W WO 2018018352 A1 WO2018018352 A1 WO 2018018352A1
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window
image
contrast images
window image
images
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PCT/CN2016/091525
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French (fr)
Chinese (zh)
Inventor
朱艳春
付楠
张志诚
余绍德
陈昳丽
谢耀钦
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深圳先进技术研究院
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Priority to PCT/CN2016/091525 priority Critical patent/WO2018018352A1/en
Publication of WO2018018352A1 publication Critical patent/WO2018018352A1/en

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    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis

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  • the invention relates to the technical field of medical clinical imaging, in particular to a method and a device for synchronous display and positioning calibration of multi-contrast images.
  • CT Computed Tomography
  • MRI Magnetic Resonance Imaging
  • US Ultrasound
  • PET Positron Emission Computed Tomography
  • DICOM Digital Imaging and Communication in Medicine
  • the embodiment of the invention provides a multi-contrast image synchronous display and positioning calibration method for synchronously displaying multiple contrast images and synchronously positioning calibration position information in multiple windows, the method comprising:
  • the window of the real mouse pointer is used as the target window, and the corresponding position on the other window image is calculated according to the position of the mouse pointer on the image of the target window and the position comparison result on the plurality of contrast images, and the virtual mouse pointer is displayed at the position.
  • scanning position information extraction and comparison calculation are performed on the plurality of contrast images, including extracting scan slice position information of the plurality of contrast images and position information in the scan layer, and performing comparison calculation deviation.
  • the plurality of contrast images are displayed in a window-by-window manner according to a position comparison result on the plurality of contrast images, including:
  • the position alignment result on the plurality of contrast images indicates that the scanning slice position information of the plurality of contrast images is different, the scanning layer thickness of the other window images according to the scanning layer number of the target window image and the scanning layer thickness, and The other window images are deviated from the scanning position of the target window image, and the adjacent layers of the other window images are searched for and displayed simultaneously.
  • the adjacent layers of other window images are searched for and displayed synchronously as follows:
  • N X Round [( ⁇ Z X + M ⁇ S) / S X ];
  • N X is the adjacent layer of the other window image
  • ⁇ Z X is the scanning position deviation of the other window image and the target window image
  • M is the scanning layer number of the target window image
  • S is the scanning layer thickness of the target window image
  • S X is Scanning layer thickness of other window images
  • Round[] indicates rounding calculation.
  • calculating a corresponding position on the other window image and displaying the virtual mouse pointer at the position according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images including:
  • the position comparison result on the plurality of contrast images indicates that the position information in the scanning layer of the plurality of contrast images is different, according to the position of the mouse pointer on the target window image, and the intra-layer position deviation of the other window image and the target window image , calculate the corresponding position on the other window image and display the virtual mouse pointer at that position.
  • the corresponding position on the other window image is calculated and the virtual mouse pointer is displayed at the position as follows:
  • (X 1 , Y 1 ) is the corresponding position on the other window image
  • (X, Y) is the position of the mouse pointer on the target window image
  • ( ⁇ X 1 , ⁇ Y 1 ) is the intra-layer position of the other window image and the target window image. deviation.
  • the method further includes:
  • the result of the operation is synchronized in the other windows according to the operation of the mouse pointer on the target window image.
  • the embodiment of the invention further provides a device for synchronous display and positioning calibration of a multi-contrast image, which is used for synchronously displaying a plurality of contrast images and synchronously positioning calibration position information in a plurality of windows, the device comprising:
  • An image obtaining module configured to obtain a plurality of contrast images of the same part of the living body
  • a position comparison module configured to perform scanning position information extraction and comparison calculation on the plurality of contrast images
  • An image display module configured to perform window-by-window synchronization display on the plurality of contrast images according to a position comparison result on the plurality of contrast images
  • a positioning calibration module configured to use a window of the real mouse pointer as a target window, and calculate a corresponding position on the other window image according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images, and display the position on the other window image Virtual mouse pointer.
  • the position comparison module is further configured to: extract scan slice position information of the plurality of contrast images and position information within the scan layer, and perform a comparison calculation deviation.
  • the image display module is further configured to:
  • the position alignment result on the plurality of contrast images indicates that the scanning slice position information of the plurality of contrast images is different, the scanning layer thickness of the other window images according to the scanning layer number of the target window image and the scanning layer thickness, and The other window images are deviated from the scanning position of the target window image, and the adjacent layers of the other window images are searched for and displayed simultaneously.
  • the image display module is further configured to find adjacent layers of other window images and display them synchronously according to the following formula:
  • N X Round [( ⁇ Z X + M ⁇ S) / S X ];
  • N X is the adjacent layer of the other window image
  • ⁇ Z X is the scanning position deviation of the other window image and the target window image
  • M is the scanning layer number of the target window image
  • S is the scanning layer thickness of the target window image
  • S X is Scanning layer thickness of other window images
  • Round[] indicates rounding calculation.
  • the positioning calibration module is further configured to:
  • the position comparison result on the plurality of contrast images indicates that the position information in the scanning layer of the plurality of contrast images is different, according to the position of the mouse pointer on the target window image, and the intra-layer position deviation of the other window image and the target window image , calculate the corresponding position on the other window image and display the virtual mouse pointer at that position.
  • the positioning calibration module is further configured to calculate a corresponding position on the other window image and display the virtual mouse pointer at the position according to the following formula:
  • (X 1 , Y 1 ) is the corresponding position on the other window image
  • (X, Y) is the position of the mouse pointer on the target window image
  • ( ⁇ X 1 , ⁇ Y 1 ) is the intra-layer position of the other window image and the target window image. deviation.
  • the apparatus further comprises:
  • the operation synchronization module is configured to synchronously display the operation result in other windows according to the operation of the mouse pointer on the target window image.
  • the plurality of contrast images are displayed in a window according to the position comparison result on the plurality of contrast images, thereby avoiding switching between the plurality of contrast images or displaying by using multiple screens;
  • the position of the mouse pointer on the image of the target window and the position comparison result on the plurality of contrast images the corresponding position on the other window image is calculated and the virtual mouse pointer is displayed at the position, thereby preventing the doctor from comparing with the naked eye or manually selecting the same image.
  • the position is compared; the implementation of the embodiment of the present invention is simple and efficient, and the accurate comparison can be easily realized. Even the comparison of high-resolution images does not add extra difficulty to the doctor.
  • FIG. 1 is a schematic diagram of a method for synchronous display and positioning calibration of multi-contrast images according to an embodiment of the present invention
  • FIG. 2 is a specific example diagram of multi-contrast image synchronous display and positioning calibration according to an embodiment of the present invention
  • FIG. 3 is a schematic diagram showing multi-window display of different data sources without scanning position deviation according to an embodiment of the present invention
  • FIG. 4 is a schematic diagram showing multi-window display of a layer deviation image source in an embodiment of the present invention.
  • FIG. 5 is a schematic diagram of calculation of a display layer when there is a layer deviation according to an embodiment of the present invention
  • FIG. 6 is a schematic diagram showing synchronous positioning display of each window when there is a positional deviation in a layer according to an embodiment of the present invention
  • FIG. 7 is a schematic diagram of synchronization operations of windows in an embodiment of the present invention.
  • FIG. 8 is a schematic diagram of an apparatus for synchronous display and positioning calibration of multi-contrast images according to an embodiment of the present invention
  • FIG. 9 is a view showing a specific example of an apparatus for synchronous display and positioning calibration of multi-contrast images according to an embodiment of the present invention.
  • the method may include:
  • Step 101 Obtain a plurality of contrast images of the same part of the living body
  • Step 102 Perform scanning position information extraction and comparison calculation on the plurality of contrast images
  • Step 103 Perform synchronous display of the plurality of contrast images according to position comparison results on the plurality of contrast images
  • Step 104 The window of the real mouse pointer is used as the target window, and according to the position of the mouse pointer on the image of the target window and the position comparison result on the plurality of contrast images, the corresponding position on the other window image is calculated and the virtual mouse pointer is displayed at the position. .
  • a plurality of contrast images of the same part of the living body are obtained first.
  • a variety of contrast images can be obtained by clinical imaging techniques, and can be a variety of scanning methods from an imaging modality, such as magnetic resonance imaging (MRI) transverse relaxation time weighted images (T2WI) and longitudinal relaxation time weighted images ( T1WI); can also be several sets of images from different imaging modalities, such as magnetic resonance images and positron emission computed tomography (PET).
  • Multi-contrast images can also be referred to as multi-image data sources. As shown in FIG. 2, each contrast image is used as an image source, and each image source can be unified into the same format, such as DICOM format, and the number of image sources can be increased or decreased according to clinical diagnosis needs.
  • the medical image in DICOM format contains a sweep
  • the scanning position information of the DICOM image of different image data sources needs to be extracted and compared.
  • the scan location information can include a variety of information related to the scan location.
  • performing scan position information extraction and comparison calculation on a plurality of contrast images may include extracting scan slice position information of a plurality of contrast images and position information within the scan layer, and performing a comparison calculation deviation.
  • the scanning plane position information may include a scanning layer number and a scanning layer thickness.
  • the medical image in DICOM format contains all the information such as image acquisition, archiving, communication, display and query.
  • the DICOM file of each image source is first read, and the image scanning position information is preprocessed.
  • the scanning position information of each image source is the same, for example, various scanning protocols in magnetic resonance imaging are used.
  • the same positioning parameter, or multi-modal imaging (such as PET / MRI) simultaneous scanning, etc. at this time the multi-data source has the same scanning plane position information and position information within the scanning layer.
  • pre-processing it is checked whether the multi-data source has the scanning position deviation in the X, Y or Z direction.
  • the obtained image source can be directly imported into each window for comparison display.
  • the number of windows can be determined by the number of data sources, which can be automatically optimized for adjustment on the display according to the number of windows.
  • 3 is a schematic diagram showing multi-window display of different data sources without scanning position deviation according to an embodiment of the present invention. As shown in FIG. 3, three kinds of contrast image sources are displayed layer by layer in three image display windows, and image sources displayed by each window are respectively displayed. In the same position, only the image contrast of each image source is different.
  • each image source has a positional deviation
  • the positional deviation may be in the layer direction, that is, the Z direction, or may be the positional deviation inside the layer, that is, the X, Y direction.
  • registration calculations are required for each data source, and the positional deviation of each data source is calculated.
  • This positional deviation includes the stiffness deviations in the three directions of X, Y, and Z, which are well known to those skilled in the art.
  • the calculation of the positional deviation can be implemented by a corresponding algorithm.
  • the plurality of contrast images are displayed in a window according to the position comparison result on the plurality of contrast images, including: if the position comparison result on the plurality of contrast images indicates that the scanning plane position information of the plurality of contrast images is different, According to the scanning layer number of the target window image and the scanning layer thickness, the scanning layer thickness of other window images, and the scanning positions of other window images and the target window image are deviated, and the adjacent layers of other window images are searched for and displayed simultaneously.
  • FIG. 4 is a schematic diagram showing multi-window display with a layer deviation image source in an embodiment of the present invention.
  • the target window can be any window, depending on where the real mouse pointer is located.
  • the target window is fixed, as shown in Figure 4, and the second window is defined as the target window.
  • the second picture is illustrated as a target window in FIG. 3-7, and any window may be selected as the target window in the actual application.
  • N X Round [( ⁇ Z X + M ⁇ S) / S X ];
  • N X is the adjacent layer of the other window image
  • ⁇ Z X is the scanning position deviation of the other window image and the target window image
  • M is the scanning layer number of the target window image
  • S is the scanning layer thickness of the target window image
  • S X is Scanning layer thickness of other window images
  • Round[] indicates rounding calculation.
  • FIG. 5 is a schematic diagram of calculation of a display level when there is a layer deviation according to an embodiment of the present invention. As shown in FIG. 5, when the target window stays at the Mth level, the remaining windows 1 and 2 respectively stay at the level closest to the target window, that is, : Round [( ⁇ Z 1 + M ⁇ S 2 ) / S 1 ] and Round [( ⁇ Z 2 + M ⁇ S 2 ) / S 3 ].
  • the corresponding position on the other window image is calculated according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images, and the virtual mouse pointer is displayed at the position.
  • the mouse pointers are all in the same position.
  • the position comparison result on the plurality of contrast images indicates that the position information in the scanning layer of the plurality of contrast images is different, according to the position of the mouse pointer on the target window image, and the layers of the other window image and the target window image.
  • the internal position deviation calculates the corresponding position on the other window image and displays the virtual mouse pointer at that position.
  • 6 is a schematic diagram showing synchronous positioning display of each window when there is a positional deviation in a layer according to an embodiment of the present invention. As shown in FIG. 6, when the position deviation of each data source appears inside the layer, that is, in the X, Y direction, according to the target window. The position where the mouse pointer stays, and the position of the remaining window pointers is calculated.
  • the corresponding position on the other window image can be calculated according to the following formula and the virtual mouse pointer is displayed at the position:
  • (X 1 , Y 1 ) is the corresponding position on the other window image
  • (X, Y) is the position of the mouse pointer on the target window image
  • ( ⁇ X 1 , ⁇ Y 1 ) is the intra-layer position of the other window image and the target window image. deviation.
  • the positional deviations of the remaining window and the image source of the target window are ( ⁇ X 1 , ⁇ Y 1 ) and ( ⁇ X 2 , ⁇ Y 2 ), respectively.
  • the mouse pointer of the window stays at the (X a , Y b ) position
  • the mouse pointer corresponding to the image of the remaining window 1 stays at (X a + ⁇ X 1 , Y a + ⁇ Y 1 )
  • the mouse pointer corresponding to the image of the remaining window 2 Stay at the position of (X a + ⁇ X 2 , Y a + ⁇ Y 2 ).
  • the corresponding mouse pointer when the real mouse pointer appears in a certain window (ie, the target window), the corresponding mouse pointer also appears in the remaining windows.
  • the mouse pointer is a virtual mouse pointer, and can also be defined as the remaining pointers.
  • the position of the image data source pointed by the mouse pointer of each sub-window is consistent.
  • the display of multiple data source images is synchronized and positional calibration can be performed simultaneously.
  • the remaining window images are automatically synchronized according to the position of the target window image, and the multi-data source image synchronization comparison display is realized.
  • the real mouse pointer stays in the data source of the target window, the mouse pointer appears in the same image position in the remaining windows.
  • the method of the embodiment of the present invention may further include: synchronously displaying the operation result in the other windows according to the operation performed by the mouse pointer on the target window image.
  • the rest of the windows will also be synchronized.
  • the remaining windows also perform corresponding actions.
  • the other windows also perform the same action response at the corresponding position.
  • FIG. 7 is a schematic diagram of synchronization operations of windows in an embodiment of the present invention. As shown in Fig.
  • each window data source when performing various operations on the target window image, such as delineating the region of interest, measuring the signal mean and variance of the region of interest, the remaining windows are also operated at the same position, and each image source has a position. In the case of deviation, the operation is performed on the basis of the positional deviation.
  • This can provide synchronization of each window data source, not only can synchronous page turning, but also can accurately synchronize the positioning of different window tissues, so that doctors can compare the performance of each image source corresponding to the same tissue position.
  • an apparatus for synchronous display and positioning calibration of multi-contrast images is also provided in the embodiment of the present invention, as described in the following embodiments. Since the principle of solving the problem of the device is similar to the method of multi-contrast image synchronous display and positioning calibration, the implementation of the device can be referred to the implementation of the multi-contrast image synchronous display and the positioning calibration method, and the repeated description will not be repeated.
  • FIG. 8 is a schematic diagram of an apparatus for synchronous display and positioning calibration of multi-contrast images according to an embodiment of the present invention.
  • the device can realize synchronous display and synchronous position calibration of the same position, multiple contrast images.
  • the apparatus may include:
  • the image obtaining module 801 is configured to obtain a plurality of contrast images of the same part of the living body
  • a position comparison module 802 configured to perform scanning position information extraction and comparison calculation on the plurality of contrast images
  • the image display module 803 is configured to perform the window-by-window synchronous display on the plurality of contrast images according to the position comparison result on the plurality of contrast images;
  • the positioning calibration module 804 is configured to use a window where the real mouse pointer is located as a target window, and calculate a corresponding position on the other window image according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images. Display a virtual mouse pointer.
  • the location comparison module 802 may be further configured to: extract scan slice location information of the plurality of contrast images and position information within the scan layer, and perform a comparison calculation deviation.
  • the image display module 803 can be further configured to:
  • the position alignment result on the plurality of contrast images indicates that the scanning slice position information of the plurality of contrast images is different, the scanning layer thickness of the other window images according to the scanning layer number of the target window image and the scanning layer thickness, and The other window images are deviated from the scanning position of the target window image, and the adjacent layers of the other window images are searched for and displayed simultaneously.
  • the image display module 803 can be further configured to find adjacent layers of other window images and display them synchronously according to the following formula:
  • N X Round [( ⁇ Z X + M ⁇ S) / S X];
  • N X is the adjacent layer of the other window image
  • ⁇ Z X is the scanning position deviation of the other window image and the target window image
  • M is the scanning layer number of the target window image
  • S is the scanning layer thickness of the target window image
  • S X is Scanning layer thickness of other window images
  • Round[] indicates rounding calculation.
  • the positioning calibration module 804 can be further used to:
  • the position comparison result on the plurality of contrast images indicates that the position information in the scanning layer of the plurality of contrast images is different, according to the position of the mouse pointer on the target window image, and the intra-layer position deviation of the other window image and the target window image , calculate the corresponding position on the other window image and display the virtual mouse pointer at that position.
  • the positioning calibration module 804 can be further configured to calculate a corresponding position on the other window image according to the following formula and display the virtual mouse pointer at the position:
  • (X 1 , Y 1 ) is the corresponding position on the other window image
  • (X, Y) is the position of the mouse pointer on the target window image
  • ( ⁇ X 1 , ⁇ Y 1 ) is the intra-layer position of the other window image and the target window image. deviation.
  • FIG. 9 is a view showing a specific example of an apparatus for synchronous display and positioning calibration of multi-contrast images according to an embodiment of the present invention. As shown in FIG. 9, in this example, the apparatus shown in FIG. 8 may further include:
  • the operation synchronization module 901 is configured to synchronously display the operation result in the other windows according to the operation performed by the mouse pointer on the target window image.
  • multiple contrast images are displayed in a window according to position comparison results on multiple contrast images, thereby avoiding switching between multiple contrast images or displaying through multiple screens;
  • the embodiment of the present invention according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images, the corresponding position on the other window image is calculated and the virtual mouse pointer is displayed at the position, thereby preventing the doctor from comparing with the naked eye, or Manually selecting the same position of each image for comparison;
  • the embodiment of the present invention is simple and efficient in implementation, and can accurately achieve accurate comparison, even if the contrast of high-resolution images does not add extra difficulty to the doctor.
  • embodiment of the present invention further provides synchronization of each window data source, which not only can synchronously turn pages, but also accurately synchronize the organization positions of different windows, so that the doctor can compare the performances in the image sources corresponding to the same tissue position.
  • embodiments of the present invention provide a solution that facilitates multi-window diagnostics, comparison, and measurement.
  • embodiments of the present invention can be provided as a method, system, or computer program product. Accordingly, the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment, or a combination of software and hardware. Moreover, the invention can take the form of a computer program product embodied on one or more computer-usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) including computer usable program code.
  • computer-usable storage media including but not limited to disk storage, CD-ROM, optical storage, etc.
  • the computer program instructions can also be stored in a computer readable memory that can direct a computer or other programmable data processing device to operate in a particular manner, such that the instructions stored in the computer readable memory produce an article of manufacture comprising the instruction device.
  • the apparatus implements the functions specified in one or more blocks of a flow or a flow and/or block diagram of the flowchart.
  • These computer program instructions can also be loaded onto a computer or other programmable data processing device such that a series of operational steps are performed on a computer or other programmable device to produce computer-implemented processing for execution on a computer or other programmable device.
  • the instructions provide steps for implementing the functions specified in one or more of the flow or in a block or blocks of a flow diagram.

Abstract

Disclosed are a synchronous display, positioning and demarcation method and device for multiple contrast images. The method comprises: obtaining multiple contrast images of the same portion of a living body; performing scanning position information extraction and comparative calculation on the multiple contrast images; according to a position comparison result of the multiple contrast images, synchronously displaying the multiple contrast images in splitter windows; and taking a window where a real mouse pointer is located as a target window, calculating the corresponding positions on the other window images according to the position of a mouse pointer on a target window image and a position comparison result of the multiple contrast images, and displaying a virtual mouse pointer at the position. The method can realize synchronous display of multiple contrast images in multiple windows and synchronous positioning and demarcation of position information.

Description

多对比度图像同步显示和定位标定的方法及装置Multi-contrast image synchronous display and positioning calibration method and device 技术领域Technical field
本发明涉及医学临床影像技术领域,尤其涉及多对比度图像同步显示和定位标定的方法及装置。The invention relates to the technical field of medical clinical imaging, in particular to a method and a device for synchronous display and positioning calibration of multi-contrast images.
背景技术Background technique
随着临床影像诊断技术的发展,为了提高疾病的诊断准确率,临床上医生往往通过分析多种对比度的图像来对疾病进行诊断和分析。对某一部位的疾病诊断,有时会采用同一种成像模态,如电子计算机断层扫描成像(Computed Tomography,CT)、磁共振成像(Magnetic Resonance Imaging,MRI)、超声成像(Ultrasound,US)和正电子发射计算机断层成像(Positron Emission Computed Tomography,PET)等,利用一种成像模态得到几种不同对比度的图像,然后根据病变部位在不同对比度图像中的表现进行诊断;有时会结合多种成像模态的优势,采用多种成像模态图像对疾病进行诊断,如PET/CT是结合正电子发射计算机断层成像和电子计算机断层扫描技术、PET/MRI是结合正电子发射计算机断层成像和磁共振成像等。所得的医学图像一般符合DICOM(Digital Imaging and Communication in Medicine)标准,该标准包含了医学数字图像的采集、归档、通信、显示及查询等所有信息交换的协议。With the development of clinical imaging diagnostic techniques, in order to improve the diagnostic accuracy of diseases, clinicians often diagnose and analyze diseases by analyzing images with multiple contrasts. For the diagnosis of a certain disease, the same imaging modality is sometimes used, such as Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Ultrasound (US), and positrons. Positron Emission Computed Tomography (PET), etc., using an imaging modality to obtain images of several different contrasts, and then based on the performance of the lesions in different contrast images; sometimes combined with multiple imaging modalities The advantage of using a variety of imaging modal images to diagnose diseases, such as PET / CT combined with positron emission computed tomography and computed tomography, PET / MRI combined with positron emission computed tomography and magnetic resonance imaging . The resulting medical images generally conform to the DICOM (Digital Imaging and Communication in Medicine) standard, which includes protocols for all information exchange such as collection, archiving, communication, display, and query of medical digital images.
当前,医生在进行多对比度图像诊断的时候,往往需要在多种对比度图像之间切换,或者通过多屏幕进行显示,然后通过肉眼进行对比,或者手动选择各图像同一位置进行对比。这种方法不仅非常低效而且在进行精准比对方面比较困难,尤其是高分辨率图像的对比,给医生增加了额外的难度,并且很难准确选择同样的位置进行比对。Currently, when doctors perform multi-contrast image diagnosis, they often need to switch between multiple contrast images, or display them through multiple screens, then compare them with the naked eye, or manually select the same position for comparison. This method is not only very inefficient but also difficult to perform accurate comparisons, especially the comparison of high-resolution images, which adds extra difficulty to the doctor and makes it difficult to accurately select the same position for comparison.
发明内容Summary of the invention
本发明实施例提供一种多对比度图像同步显示和定位标定的方法,用以实现在多窗口中同步显示多种对比度图像和同步定位标定位置信息,该方法包括:The embodiment of the invention provides a multi-contrast image synchronous display and positioning calibration method for synchronously displaying multiple contrast images and synchronously positioning calibration position information in multiple windows, the method comprising:
获得生物体同一部位的多种对比度图像;Obtaining multiple contrast images of the same part of the organism;
对所述多种对比度图像进行扫描位置信息提取和对比计算;Performing scanning position information extraction and comparison calculation on the plurality of contrast images;
根据所述多种对比度图像上的位置对比结果将所述多种对比度图像进行分窗口同步显示; And displaying the plurality of contrast images in a window-by-window manner according to the position comparison result on the plurality of contrast images;
将真实鼠标指针所在窗口作为目标窗口,根据目标窗口图像上的鼠标指针位置及所述多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。The window of the real mouse pointer is used as the target window, and the corresponding position on the other window image is calculated according to the position of the mouse pointer on the image of the target window and the position comparison result on the plurality of contrast images, and the virtual mouse pointer is displayed at the position.
一个实施例中,对所述多种对比度图像进行扫描位置信息提取和对比计算,包括提取所述多种对比度图像的扫描层面位置信息和扫描层内位置信息,并进行对比计算偏差。In one embodiment, scanning position information extraction and comparison calculation are performed on the plurality of contrast images, including extracting scan slice position information of the plurality of contrast images and position information in the scan layer, and performing comparison calculation deviation.
一个实施例中,根据所述多种对比度图像上的位置对比结果将所述多种对比度图像进行分窗口同步显示,包括:In one embodiment, the plurality of contrast images are displayed in a window-by-window manner according to a position comparison result on the plurality of contrast images, including:
若所述多种对比度图像上的位置比对结果表明所述多种对比度图像的扫描层面位置信息不同,则根据目标窗口图像的扫描层数及扫描层厚,其它窗口图像的扫描层厚,以及其它窗口图像与目标窗口图像的扫描位置偏差,查找其它窗口图像的临近层面并同步显示。If the position alignment result on the plurality of contrast images indicates that the scanning slice position information of the plurality of contrast images is different, the scanning layer thickness of the other window images according to the scanning layer number of the target window image and the scanning layer thickness, and The other window images are deviated from the scanning position of the target window image, and the adjacent layers of the other window images are searched for and displayed simultaneously.
一个实施例中,按如下公式查找其它窗口图像的临近层面并同步显示:In one embodiment, the adjacent layers of other window images are searched for and displayed synchronously as follows:
NX=Round[(ΔZX+M×S)/SX];N X = Round [(ΔZ X + M × S) / S X ];
其中,NX为其它窗口图像的临近层面,ΔZX为其它窗口图像与目标窗口图像的扫描位置偏差;M为目标窗口图像的扫描层数;S为目标窗口图像的扫描层厚;SX为其它窗口图像的扫描层厚;Round[]表示四舍五入计算。Wherein, N X is the adjacent layer of the other window image, ΔZ X is the scanning position deviation of the other window image and the target window image; M is the scanning layer number of the target window image; S is the scanning layer thickness of the target window image; S X is Scanning layer thickness of other window images; Round[] indicates rounding calculation.
一个实施例中,根据目标窗口图像上鼠标指针位置及所述多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针,包括:In one embodiment, calculating a corresponding position on the other window image and displaying the virtual mouse pointer at the position according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images, including:
若所述多种对比度图像上的位置对比结果表明所述多种对比度图像的扫描层内位置信息不同,则根据目标窗口图像上鼠标指针位置,以及其它窗口图像与目标窗口图像的层内位置偏差,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。If the position comparison result on the plurality of contrast images indicates that the position information in the scanning layer of the plurality of contrast images is different, according to the position of the mouse pointer on the target window image, and the intra-layer position deviation of the other window image and the target window image , calculate the corresponding position on the other window image and display the virtual mouse pointer at that position.
一个实施例中,按如下公式计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针:In one embodiment, the corresponding position on the other window image is calculated and the virtual mouse pointer is displayed at the position as follows:
(X1,Y1)=(X+ΔX1,Y+ΔY1);(X 1 , Y 1 )=(X+ΔX 1 , Y+ΔY 1 );
其中,(X1,Y1)为其它窗口图像上对应位置,(X,Y)为目标窗口图像上鼠标指针位置,(ΔX1,ΔY1)为其它窗口图像与目标窗口图像的层内位置偏差。Where (X 1 , Y 1 ) is the corresponding position on the other window image, (X, Y) is the position of the mouse pointer on the target window image, and (ΔX 1 , ΔY 1 ) is the intra-layer position of the other window image and the target window image. deviation.
一个实施例中,该方法还包括:In one embodiment, the method further includes:
根据鼠标指针在目标窗口图像上所做的操作,在其它各窗口中同步显示操作结果。 The result of the operation is synchronized in the other windows according to the operation of the mouse pointer on the target window image.
本发明实施例还提供一种多对比度图像同步显示和定位标定的装置,用以实现在多窗口中同步显示多种对比度图像和同步定位标定位置信息,该装置包括:The embodiment of the invention further provides a device for synchronous display and positioning calibration of a multi-contrast image, which is used for synchronously displaying a plurality of contrast images and synchronously positioning calibration position information in a plurality of windows, the device comprising:
图像获得模块,用于获得生物体同一部位的多种对比度图像;An image obtaining module, configured to obtain a plurality of contrast images of the same part of the living body;
位置对比模块,用于对所述多种对比度图像进行扫描位置信息提取和对比计算;a position comparison module, configured to perform scanning position information extraction and comparison calculation on the plurality of contrast images;
图像显示模块,用于根据所述多种对比度图像上的位置对比结果将所述多种对比度图像进行分窗口同步显示;An image display module, configured to perform window-by-window synchronization display on the plurality of contrast images according to a position comparison result on the plurality of contrast images;
定位标定模块,用于将真实鼠标指针所在窗口作为目标窗口,根据目标窗口图像上的鼠标指针位置及所述多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。a positioning calibration module, configured to use a window of the real mouse pointer as a target window, and calculate a corresponding position on the other window image according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images, and display the position on the other window image Virtual mouse pointer.
一个实施例中,所述位置对比模块进一步用于:提取所述多种对比度图像的扫描层面位置信息和扫描层内位置信息,并进行对比计算偏差。In one embodiment, the position comparison module is further configured to: extract scan slice position information of the plurality of contrast images and position information within the scan layer, and perform a comparison calculation deviation.
一个实施例中,所述图像显示模块进一步用于:In one embodiment, the image display module is further configured to:
若所述多种对比度图像上的位置比对结果表明所述多种对比度图像的扫描层面位置信息不同,则根据目标窗口图像的扫描层数及扫描层厚,其它窗口图像的扫描层厚,以及其它窗口图像与目标窗口图像的扫描位置偏差,查找其它窗口图像的临近层面并同步显示。If the position alignment result on the plurality of contrast images indicates that the scanning slice position information of the plurality of contrast images is different, the scanning layer thickness of the other window images according to the scanning layer number of the target window image and the scanning layer thickness, and The other window images are deviated from the scanning position of the target window image, and the adjacent layers of the other window images are searched for and displayed simultaneously.
一个实施例中,所述图像显示模块进一步用于按如下公式查找其它窗口图像的临近层面并同步显示:In one embodiment, the image display module is further configured to find adjacent layers of other window images and display them synchronously according to the following formula:
NX=Round[(ΔZX+M×S)/SX];N X = Round [(ΔZ X + M × S) / S X ];
其中,NX为其它窗口图像的临近层面,ΔZX为其它窗口图像与目标窗口图像的扫描位置偏差;M为目标窗口图像的扫描层数;S为目标窗口图像的扫描层厚;SX为其它窗口图像的扫描层厚;Round[]表示四舍五入计算。Wherein, N X is the adjacent layer of the other window image, ΔZ X is the scanning position deviation of the other window image and the target window image; M is the scanning layer number of the target window image; S is the scanning layer thickness of the target window image; S X is Scanning layer thickness of other window images; Round[] indicates rounding calculation.
一个实施例中,所述定位标定模块进一步用于:In one embodiment, the positioning calibration module is further configured to:
若所述多种对比度图像上的位置对比结果表明所述多种对比度图像的扫描层内位置信息不同,则根据目标窗口图像上鼠标指针位置,以及其它窗口图像与目标窗口图像的层内位置偏差,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。If the position comparison result on the plurality of contrast images indicates that the position information in the scanning layer of the plurality of contrast images is different, according to the position of the mouse pointer on the target window image, and the intra-layer position deviation of the other window image and the target window image , calculate the corresponding position on the other window image and display the virtual mouse pointer at that position.
一个实施例中,所述定位标定模块进一步用于按如下公式计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针:In one embodiment, the positioning calibration module is further configured to calculate a corresponding position on the other window image and display the virtual mouse pointer at the position according to the following formula:
(X1,Y1)=(X+ΔX1,Y+ΔY1); (X 1, Y 1) = (X + ΔX 1, Y + ΔY 1);
其中,(X1,Y1)为其它窗口图像上对应位置,(X,Y)为目标窗口图像上鼠标指针位置,(ΔX1,ΔY1)为其它窗口图像与目标窗口图像的层内位置偏差。Where (X 1 , Y 1 ) is the corresponding position on the other window image, (X, Y) is the position of the mouse pointer on the target window image, and (ΔX 1 , ΔY 1 ) is the intra-layer position of the other window image and the target window image. deviation.
一个实施例中,该装置还包括:In one embodiment, the apparatus further comprises:
操作同步模块,用于根据鼠标指针在目标窗口图像上所做的操作,在其它各窗口中同步显示操作结果。The operation synchronization module is configured to synchronously display the operation result in other windows according to the operation of the mouse pointer on the target window image.
本发明实施例中根据多种对比度图像上的位置对比结果将多种对比度图像进行分窗口同步显示,避免了在多种对比度图像之间进行切换,或者通过多屏幕进行显示;本发明实施例中根据目标窗口图像上的鼠标指针位置及多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针,避免了医生通过肉眼进行对比,或者手动选择各图像同一位置进行对比;本发明实施例实施过程简单高效,并且能够很容易地实现精准比对,即使是高分辨率图像的对比,也不会给医生增加额外的难度。In the embodiment of the present invention, the plurality of contrast images are displayed in a window according to the position comparison result on the plurality of contrast images, thereby avoiding switching between the plurality of contrast images or displaying by using multiple screens; According to the position of the mouse pointer on the image of the target window and the position comparison result on the plurality of contrast images, the corresponding position on the other window image is calculated and the virtual mouse pointer is displayed at the position, thereby preventing the doctor from comparing with the naked eye or manually selecting the same image. The position is compared; the implementation of the embodiment of the present invention is simple and efficient, and the accurate comparison can be easily realized. Even the comparison of high-resolution images does not add extra difficulty to the doctor.
附图说明DRAWINGS
为了更清楚地说明本发明实施例中的技术方案,下面将对实施例描述中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本发明的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的附图。在附图中:In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly described below. It is obvious that the drawings in the following description are only some embodiments of the present invention. Other drawings may also be obtained from those of ordinary skill in the art in light of the inventive work. In the drawing:
图1为本发明实施例中多对比度图像同步显示和定位标定的方法示意图;1 is a schematic diagram of a method for synchronous display and positioning calibration of multi-contrast images according to an embodiment of the present invention;
图2为本发明实施例中多对比度图像同步显示和定位标定的具体实例图;2 is a specific example diagram of multi-contrast image synchronous display and positioning calibration according to an embodiment of the present invention;
图3为本发明实施例中没有扫描位置偏差的不同数据源多窗口显示示意图;3 is a schematic diagram showing multi-window display of different data sources without scanning position deviation according to an embodiment of the present invention;
图4为本发明实施例中有层面偏差图像源的多窗口显示示意图;4 is a schematic diagram showing multi-window display of a layer deviation image source in an embodiment of the present invention;
图5为本发明实施例中有层面偏差时显示层面计算示意图;FIG. 5 is a schematic diagram of calculation of a display layer when there is a layer deviation according to an embodiment of the present invention; FIG.
图6为本发明实施例中有层内位置偏差时各窗口的同步定位显示示意图;6 is a schematic diagram showing synchronous positioning display of each window when there is a positional deviation in a layer according to an embodiment of the present invention;
图7为本发明实施例中各窗口同步操作示意图;FIG. 7 is a schematic diagram of synchronization operations of windows in an embodiment of the present invention; FIG.
图8为本发明实施例中多对比度图像同步显示和定位标定的装置示意图;8 is a schematic diagram of an apparatus for synchronous display and positioning calibration of multi-contrast images according to an embodiment of the present invention;
图9为本发明实施例中多对比度图像同步显示和定位标定的装置的具体实例图。FIG. 9 is a view showing a specific example of an apparatus for synchronous display and positioning calibration of multi-contrast images according to an embodiment of the present invention.
具体实施方式 detailed description
为使本发明实施例的目的、技术方案和优点更加清楚明白,下面结合附图对本发明实施例做进一步详细说明。在此,本发明的示意性实施例及其说明用于解释本发明,但并不作为对本发明的限定。The embodiments of the present invention will be further described in detail below with reference to the accompanying drawings. The illustrative embodiments of the present invention and the description thereof are intended to explain the present invention, but are not intended to limit the invention.
为了实现在多窗口中同步显示多种对比度图像和进行准确位置同步标定,本发明实施例中提供一种多对比度图像同步显示和定位标定的方法,如图1所示,该方法可以包括:In order to realize synchronous display of multiple contrast images in multiple windows and accurate position synchronization calibration, a method for synchronous display and positioning calibration of multi-contrast images is provided in the embodiment of the present invention. As shown in FIG. 1 , the method may include:
步骤101、获得生物体同一部位的多种对比度图像;Step 101: Obtain a plurality of contrast images of the same part of the living body;
步骤102、对所述多种对比度图像进行扫描位置信息提取和对比计算;Step 102: Perform scanning position information extraction and comparison calculation on the plurality of contrast images;
步骤103、根据所述多种对比度图像上的位置对比结果将所述多种对比度图像进行分窗口同步显示;Step 103: Perform synchronous display of the plurality of contrast images according to position comparison results on the plurality of contrast images;
步骤104、将真实鼠标指针所在窗口作为目标窗口,根据目标窗口图像上的鼠标指针位置及所述多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。Step 104: The window of the real mouse pointer is used as the target window, and according to the position of the mouse pointer on the image of the target window and the position comparison result on the plurality of contrast images, the corresponding position on the other window image is calculated and the virtual mouse pointer is displayed at the position. .
由图1所示流程可以得知,本发明实施例中根据多种对比度图像上的位置对比结果将多种对比度图像进行分窗口同步显示,避免了在多种对比度图像之间进行切换,或者通过多屏幕进行显示;本发明实施例中根据目标窗口图像上的鼠标指针位置及多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针,避免了医生通过肉眼进行对比,或者手动选择各图像同一位置进行对比;本发明实施例实施过程简单高效,并且能够很容易地实现精准比对,即使是高分辨率图像的对比,也不会给医生增加额外的难度。It can be seen from the flow shown in FIG. 1 that in the embodiment of the present invention, multiple contrast images are displayed in a window according to position comparison results on multiple contrast images, thereby avoiding switching between multiple contrast images, or Multi-screen display; in the embodiment of the invention, according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images, the corresponding position on the other window image is calculated and the virtual mouse pointer is displayed at the position, thereby avoiding the doctor passing Compare with the naked eye, or manually select the same position for comparison. The implementation of the embodiment of the present invention is simple and efficient, and the accurate comparison can be easily realized. Even the comparison of high-resolution images does not add extra to the doctor. Difficulty.
具体实施时,先获得生物体同一部位的多种对比度图像。多种对比度图像可以通过临床影像技术获得,可以是来自一种成像模态的多种扫描方法,比如磁共振成像(MRI)的横向弛豫时间加权图像(T2WI)和纵向弛豫时间加权图像(T1WI);也可以是来自不同成像模态的几组图像,比如磁共振图像和正电子发射计算机断层成像(PET)。多对比度图像也可称为多图像数据源。如图2所示,每一种对比度图像作为一种图像源,各图像源可以都统一为同种格式,如DICOM格式,图像源的数量根据临床诊断需要可随意增减。In a specific implementation, a plurality of contrast images of the same part of the living body are obtained first. A variety of contrast images can be obtained by clinical imaging techniques, and can be a variety of scanning methods from an imaging modality, such as magnetic resonance imaging (MRI) transverse relaxation time weighted images (T2WI) and longitudinal relaxation time weighted images ( T1WI); can also be several sets of images from different imaging modalities, such as magnetic resonance images and positron emission computed tomography (PET). Multi-contrast images can also be referred to as multi-image data sources. As shown in FIG. 2, each contrast image is used as an image source, and each image source can be unified into the same format, such as DICOM format, and the number of image sources can be increased or decreased according to clinical diagnosis needs.
在获得了生物体同一部位的多种对比度图像之后,对所述多种对比度图像进行扫描位置信息提取和对比计算,再根据多种对比度图像上的位置对比结果将多种对比度图像进行分窗口同步显示。例如,在图1的示例中,由于DICOM格式的医学图像包含了扫 描位置信息,为了便于对多窗口同位置的图像对照,需要对不同图像数据源的DICOM图像的扫描位置信息进行提取和对比计算。扫描位置信息可以包括多种与扫描位置相关的信息。例如,在一个实施例中,对多种对比度图像进行扫描位置信息提取和对比计算,可以包括提取多种对比度图像的扫描层面位置信息和扫描层内位置信息,并进行对比计算偏差。其中扫描层面位置信息可以包括扫描层数及扫描层厚。After obtaining a plurality of contrast images of the same part of the living body, scanning and comparing the scanning position information of the plurality of contrast images, and then synchronizing the plurality of contrast images according to the position comparison result on the plurality of contrast images display. For example, in the example of Figure 1, the medical image in DICOM format contains a sweep To scan the position information, in order to facilitate the image comparison of the multi-window and the same position, the scanning position information of the DICOM image of different image data sources needs to be extracted and compared. The scan location information can include a variety of information related to the scan location. For example, in one embodiment, performing scan position information extraction and comparison calculation on a plurality of contrast images may include extracting scan slice position information of a plurality of contrast images and position information within the scan layer, and performing a comparison calculation deviation. The scanning plane position information may include a scanning layer number and a scanning layer thickness.
在图2的示例中,DICOM格式的医学图像包含了图像采集、归档、通信、显示及查询等所有信息。如图2所示,首先对各图像源的DICOM文件进行读取,对图像扫描位置信息进行预处理,当各图像源的扫描位置信息相同时,比如磁共振成像中的多种扫描协议使用了同一个定位参数,或者多模态成像(如PET/MRI)同时进行的扫描等,此时多数据源具有相同的扫描层面位置信息和扫描层内位置信息。通过预处理,检查多数据源是否具有X,Y或者Z方向上的扫描位置偏差,如果多数据源没有位置偏差,可以直接将所得的图像源导入到各个窗口进行对比显示。窗口的数量可以由数据源数量来决定,窗口大小可以按着窗口数量在显示器上自动最优化调整。图3为本发明实施例中没有扫描位置偏差的不同数据源多窗口显示示意图,如图3所示,三种对比度图像源在三个图像显示窗口逐层显示,各窗口所显示的图像源均处于同一位置,只是各图像信号源的图像对比度不同而已。In the example of Figure 2, the medical image in DICOM format contains all the information such as image acquisition, archiving, communication, display and query. As shown in FIG. 2, the DICOM file of each image source is first read, and the image scanning position information is preprocessed. When the scanning position information of each image source is the same, for example, various scanning protocols in magnetic resonance imaging are used. The same positioning parameter, or multi-modal imaging (such as PET / MRI) simultaneous scanning, etc., at this time the multi-data source has the same scanning plane position information and position information within the scanning layer. Through pre-processing, it is checked whether the multi-data source has the scanning position deviation in the X, Y or Z direction. If the multi-data source has no positional deviation, the obtained image source can be directly imported into each window for comparison display. The number of windows can be determined by the number of data sources, which can be automatically optimized for adjustment on the display according to the number of windows. 3 is a schematic diagram showing multi-window display of different data sources without scanning position deviation according to an embodiment of the present invention. As shown in FIG. 3, three kinds of contrast image sources are displayed layer by layer in three image display windows, and image sources displayed by each window are respectively displayed. In the same position, only the image contrast of each image source is different.
当各图像源的扫描位置不完全相同时,各图像源就会有位置偏差,位置偏差可以是层面方向上,即Z方向,也可以是层面内部的位置偏差,即X,Y方向。为了使各窗口显示的图像同步,需要对各数据源进行配准计算,计算各数据源的位置偏差,这个位置偏差包括X,Y,Z三个方向上的刚性偏差,本领域技术人员熟知,位置偏差的计算可以采用相应的算法实现。When the scanning positions of the image sources are not completely the same, each image source has a positional deviation, and the positional deviation may be in the layer direction, that is, the Z direction, or may be the positional deviation inside the layer, that is, the X, Y direction. In order to synchronize the images displayed by the windows, registration calculations are required for each data source, and the positional deviation of each data source is calculated. This positional deviation includes the stiffness deviations in the three directions of X, Y, and Z, which are well known to those skilled in the art. The calculation of the positional deviation can be implemented by a corresponding algorithm.
具体实施时,根据多种对比度图像上的位置对比结果将多种对比度图像进行分窗口同步显示,包括:若多种对比度图像上的位置对比结果表明多种对比度图像的扫描层面位置信息不同,则根据目标窗口图像的扫描层数及扫描层厚,其它窗口图像的扫描层厚,以及其它窗口图像与目标窗口图像的扫描位置偏差,查找其它窗口图像的临近层面并同步显示。In a specific implementation, the plurality of contrast images are displayed in a window according to the position comparison result on the plurality of contrast images, including: if the position comparison result on the plurality of contrast images indicates that the scanning plane position information of the plurality of contrast images is different, According to the scanning layer number of the target window image and the scanning layer thickness, the scanning layer thickness of other window images, and the scanning positions of other window images and the target window image are deviated, and the adjacent layers of other window images are searched for and displayed simultaneously.
图4是本发明实施例中有层面偏差图像源的多窗口显示示意图。如图4所示,当各数据源有位置偏差时,如果位置偏差在层面Z方向,根据目标窗口所停留的层面决定其余窗口所显示的层面。目标窗口可以是任何一个窗口,根据真实鼠标指针所处位置来决 定目标窗口,如图4所示,第二个窗口被定义为目标窗口。为了示意方便,在图3-7中将第二幅图示意为目标窗口,实际应用中可以选择任一窗口作为目标窗口。4 is a schematic diagram showing multi-window display with a layer deviation image source in an embodiment of the present invention. As shown in FIG. 4, when each data source has a positional deviation, if the positional deviation is in the plane Z direction, the level displayed by the remaining windows is determined according to the level at which the target window stays. The target window can be any window, depending on where the real mouse pointer is located. The target window is fixed, as shown in Figure 4, and the second window is defined as the target window. For convenience of illustration, the second picture is illustrated as a target window in FIG. 3-7, and any window may be selected as the target window in the actual application.
具体实施时,可以按如下公式查找其它窗口图像的临近层面并同步显示:In the specific implementation, you can find the adjacent layers of other window images and display them synchronously according to the following formula:
NX=Round[(ΔZX+M×S)/SX];N X = Round [(ΔZ X + M × S) / S X ];
其中,NX为其它窗口图像的临近层面,ΔZX为其它窗口图像与目标窗口图像的扫描位置偏差;M为目标窗口图像的扫描层数;S为目标窗口图像的扫描层厚;SX为其它窗口图像的扫描层厚;Round[]表示四舍五入计算。Wherein, N X is the adjacent layer of the other window image, ΔZ X is the scanning position deviation of the other window image and the target window image; M is the scanning layer number of the target window image; S is the scanning layer thickness of the target window image; S X is Scanning layer thickness of other window images; Round[] indicates rounding calculation.
在图4的示例中,假设各图像数据源图像的层厚为S1,S2,S3,其余窗口1和2与目标窗口的位置偏差分别为ΔZ1和ΔZ2。图5为本发明实施例中有层面偏差时显示层面计算示意图,如图5所示,当目标窗口停留在第M层面时,其余窗口1和2分别会停留在离目标窗口最近的层面,即:Round[(ΔZ1+M×S2)/S1]和Round[(ΔZ2+M×S2)/S3]。In the example of FIG. 4, it is assumed that the layer thicknesses of the respective image data source images are S 1 , S 2 , S 3 , and the positional deviations of the remaining windows 1 and 2 from the target window are ΔZ 1 and ΔZ 2 , respectively . FIG. 5 is a schematic diagram of calculation of a display level when there is a layer deviation according to an embodiment of the present invention. As shown in FIG. 5, when the target window stays at the Mth level, the remaining windows 1 and 2 respectively stay at the level closest to the target window, that is, : Round [(ΔZ 1 + M × S 2 ) / S 1 ] and Round [(ΔZ 2 + M × S 2 ) / S 3 ].
在将多种对比度图像进行分窗口同步显示后,根据目标窗口图像上的鼠标指针位置及所述多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。在图3的示例中,没有扫描位置偏差的不同数据源多窗口中,鼠标指针均处于同一位置。After performing multiple window contrast display, the corresponding position on the other window image is calculated according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images, and the virtual mouse pointer is displayed at the position. . In the example of FIG. 3, in the different data sources without scanning position deviations, the mouse pointers are all in the same position.
在其它的实施例中,若多种对比度图像上的位置对比结果表明多种对比度图像的扫描层内位置信息不同,则根据目标窗口图像上鼠标指针位置,以及其它窗口图像与目标窗口图像的层内位置偏差,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。图6为本发明实施例中有层内位置偏差时各窗口的同步定位显示示意图,如图6所示,当各数据源位置偏差出现在层面内部,即X,Y方向上时,根据目标窗口鼠标指针停留的位置,计算出其余窗口指针的定位位置。In other embodiments, if the position comparison result on the plurality of contrast images indicates that the position information in the scanning layer of the plurality of contrast images is different, according to the position of the mouse pointer on the target window image, and the layers of the other window image and the target window image. The internal position deviation calculates the corresponding position on the other window image and displays the virtual mouse pointer at that position. 6 is a schematic diagram showing synchronous positioning display of each window when there is a positional deviation in a layer according to an embodiment of the present invention. As shown in FIG. 6, when the position deviation of each data source appears inside the layer, that is, in the X, Y direction, according to the target window. The position where the mouse pointer stays, and the position of the remaining window pointers is calculated.
具体的,可以按如下公式计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针:Specifically, the corresponding position on the other window image can be calculated according to the following formula and the virtual mouse pointer is displayed at the position:
(X1,Y1)=(X+ΔX1,Y+ΔY1);(X 1 , Y 1 )=(X+ΔX 1 , Y+ΔY 1 );
其中,(X1,Y1)为其它窗口图像上对应位置,(X,Y)为目标窗口图像上鼠标指针位置,(ΔX1,ΔY1)为其它窗口图像与目标窗口图像的层内位置偏差。Where (X 1 , Y 1 ) is the corresponding position on the other window image, (X, Y) is the position of the mouse pointer on the target window image, and (ΔX 1 , ΔY 1 ) is the intra-layer position of the other window image and the target window image. deviation.
在图6的示例中,假设数据源位置偏差在X,Y方向上,其余窗口与目标窗口的图像源的位置偏差分别为(ΔX1,ΔY1)和(ΔX2,ΔY2),当目标窗口的鼠标指针停留在(Xa,Yb)位 置时,其余窗口1的图像对应的鼠标指针停留在(Xa+ΔX1,Ya+ΔY1),其余窗口2的图像对应的鼠标指针停留在在(Xa+ΔX2,Ya+ΔY2)位置。In the example of FIG. 6, assuming that the data source position deviation is in the X, Y direction, the positional deviations of the remaining window and the image source of the target window are (ΔX 1 , ΔY 1 ) and (ΔX 2 , ΔY 2 ), respectively. When the mouse pointer of the window stays at the (X a , Y b ) position, the mouse pointer corresponding to the image of the remaining window 1 stays at (X a + ΔX 1 , Y a + ΔY 1 ), and the mouse pointer corresponding to the image of the remaining window 2 Stay at the position of (X a + ΔX 2 , Y a + ΔY 2 ).
如图3和图6所示,当真实鼠标指针在某一窗(即目标窗口)出现时,其余窗口也会出现对应的鼠标指针,该鼠标指针为虚拟鼠标指针,也可以被定义为其余指针,并且各分窗口鼠标指针所指的图像数据源的位置是一致的。总之,多数据源图像的显示是同步的,并且可以同步进行位置标定。目标窗口的数据源图像变化时,其余窗口图像根据目标窗口图像所处位置自动同步显示,实现多数据源图像同步对比显示。真实鼠标指针在目标窗口的数据源停留时,其余窗口同一图像位置也会出现鼠标指针。As shown in FIG. 3 and FIG. 6, when the real mouse pointer appears in a certain window (ie, the target window), the corresponding mouse pointer also appears in the remaining windows. The mouse pointer is a virtual mouse pointer, and can also be defined as the remaining pointers. And the position of the image data source pointed by the mouse pointer of each sub-window is consistent. In summary, the display of multiple data source images is synchronized and positional calibration can be performed simultaneously. When the data source image of the target window changes, the remaining window images are automatically synchronized according to the position of the target window image, and the multi-data source image synchronization comparison display is realized. When the real mouse pointer stays in the data source of the target window, the mouse pointer appears in the same image position in the remaining windows.
具体实施时,本发明实施例方法还可以包括:根据鼠标指针在目标窗口图像上所做的操作,在其它各窗口中同步显示操作结果。对目标窗口的数据源图像做任何操作时,其余窗口也会进行同步的动作。当对某一目标窗口的显示图像进行操作时,比如翻页操作,其余窗口也做出对应的动作。对某一目标窗口的图像做勾画计算操作时,其余窗口也在相应位置做出同样的动作响应。图7为本发明实施例中各窗口同步操作示意图。如图7所示,当对目标窗口图像做各种操作时,比如勾画感兴趣区,测量感兴趣区的信号平均值和方差,其余窗口也会在同样的位置进行操作,各图像源有位置偏差时,在位置偏差基础上进行操作。这样可以提供各窗口数据源的同步,不仅可以同步翻页,还可以准确同步定位不同窗口的组织位置,方便医生比较同一组织位置对应的各图像源中的表现。In a specific implementation, the method of the embodiment of the present invention may further include: synchronously displaying the operation result in the other windows according to the operation performed by the mouse pointer on the target window image. When you do anything with the data source image of the target window, the rest of the windows will also be synchronized. When an operation is performed on a display image of a certain target window, such as a page turning operation, the remaining windows also perform corresponding actions. When the calculation operation of the image of a certain target window is performed, the other windows also perform the same action response at the corresponding position. FIG. 7 is a schematic diagram of synchronization operations of windows in an embodiment of the present invention. As shown in Fig. 7, when performing various operations on the target window image, such as delineating the region of interest, measuring the signal mean and variance of the region of interest, the remaining windows are also operated at the same position, and each image source has a position. In the case of deviation, the operation is performed on the basis of the positional deviation. This can provide synchronization of each window data source, not only can synchronous page turning, but also can accurately synchronize the positioning of different window tissues, so that doctors can compare the performance of each image source corresponding to the same tissue position.
基于同一发明构思,本发明实施例中还提供了一种多对比度图像同步显示和定位标定的装置,如下面的实施例所述。由于该装置解决问题的原理与多对比度图像同步显示和定位标定的方法相似,因此该装置的实施可以参见多对比度图像同步显示和定位标定的方法的实施,重复之处不再赘述。Based on the same inventive concept, an apparatus for synchronous display and positioning calibration of multi-contrast images is also provided in the embodiment of the present invention, as described in the following embodiments. Since the principle of solving the problem of the device is similar to the method of multi-contrast image synchronous display and positioning calibration, the implementation of the device can be referred to the implementation of the multi-contrast image synchronous display and the positioning calibration method, and the repeated description will not be repeated.
图8为本发明实施例中多对比度图像同步显示和定位标定的装置示意图。该装置可以实现同一位置、多种对比度图像的同步显示和同步位置标定。如图8所示,该装置可以包括:FIG. 8 is a schematic diagram of an apparatus for synchronous display and positioning calibration of multi-contrast images according to an embodiment of the present invention. The device can realize synchronous display and synchronous position calibration of the same position, multiple contrast images. As shown in FIG. 8, the apparatus may include:
图像获得模块801,用于获得生物体同一部位的多种对比度图像;The image obtaining module 801 is configured to obtain a plurality of contrast images of the same part of the living body;
位置对比模块802,用于对所述多种对比度图像进行扫描位置信息提取和对比计算;a position comparison module 802, configured to perform scanning position information extraction and comparison calculation on the plurality of contrast images;
图像显示模块803,用于根据所述多种对比度图像上的位置对比结果将所述多种对比度图像进行分窗口同步显示; The image display module 803 is configured to perform the window-by-window synchronous display on the plurality of contrast images according to the position comparison result on the plurality of contrast images;
定位标定模块804,用于将真实鼠标指针所在窗口作为目标窗口,根据目标窗口图像上的鼠标指针位置及所述多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。The positioning calibration module 804 is configured to use a window where the real mouse pointer is located as a target window, and calculate a corresponding position on the other window image according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images. Display a virtual mouse pointer.
具体实施时,位置对比模块802可以进一步用于:提取所述多种对比度图像的扫描层面位置信息和扫描层内位置信息,并进行对比计算偏差。In a specific implementation, the location comparison module 802 may be further configured to: extract scan slice location information of the plurality of contrast images and position information within the scan layer, and perform a comparison calculation deviation.
具体实施时,图像显示模块803可以进一步用于:In a specific implementation, the image display module 803 can be further configured to:
若所述多种对比度图像上的位置比对结果表明所述多种对比度图像的扫描层面位置信息不同,则根据目标窗口图像的扫描层数及扫描层厚,其它窗口图像的扫描层厚,以及其它窗口图像与目标窗口图像的扫描位置偏差,查找其它窗口图像的临近层面并同步显示。If the position alignment result on the plurality of contrast images indicates that the scanning slice position information of the plurality of contrast images is different, the scanning layer thickness of the other window images according to the scanning layer number of the target window image and the scanning layer thickness, and The other window images are deviated from the scanning position of the target window image, and the adjacent layers of the other window images are searched for and displayed simultaneously.
具体实施时,图像显示模块803可以进一步用于按如下公式查找其它窗口图像的临近层面并同步显示:In a specific implementation, the image display module 803 can be further configured to find adjacent layers of other window images and display them synchronously according to the following formula:
NX=Round[(ΔZX+M×S)/SX]; N X = Round [(ΔZ X + M × S) / S X];
其中,NX为其它窗口图像的临近层面,ΔZX为其它窗口图像与目标窗口图像的扫描位置偏差;M为目标窗口图像的扫描层数;S为目标窗口图像的扫描层厚;SX为其它窗口图像的扫描层厚;Round[]表示四舍五入计算。Wherein, N X is the adjacent layer of the other window image, ΔZ X is the scanning position deviation of the other window image and the target window image; M is the scanning layer number of the target window image; S is the scanning layer thickness of the target window image; S X is Scanning layer thickness of other window images; Round[] indicates rounding calculation.
具体实施时,定位标定模块804可以进一步用于:In a specific implementation, the positioning calibration module 804 can be further used to:
若所述多种对比度图像上的位置对比结果表明所述多种对比度图像的扫描层内位置信息不同,则根据目标窗口图像上鼠标指针位置,以及其它窗口图像与目标窗口图像的层内位置偏差,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。If the position comparison result on the plurality of contrast images indicates that the position information in the scanning layer of the plurality of contrast images is different, according to the position of the mouse pointer on the target window image, and the intra-layer position deviation of the other window image and the target window image , calculate the corresponding position on the other window image and display the virtual mouse pointer at that position.
具体实施时,定位标定模块804可以进一步用于按如下公式计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针:In a specific implementation, the positioning calibration module 804 can be further configured to calculate a corresponding position on the other window image according to the following formula and display the virtual mouse pointer at the position:
(X1,Y1)=(X+ΔX1,Y+ΔY1);(X 1 , Y 1 )=(X+ΔX 1 , Y+ΔY 1 );
其中,(X1,Y1)为其它窗口图像上对应位置,(X,Y)为目标窗口图像上鼠标指针位置,(ΔX1,ΔY1)为其它窗口图像与目标窗口图像的层内位置偏差。Where (X 1 , Y 1 ) is the corresponding position on the other window image, (X, Y) is the position of the mouse pointer on the target window image, and (ΔX 1 , ΔY 1 ) is the intra-layer position of the other window image and the target window image. deviation.
图9为本发明实施例中多对比度图像同步显示和定位标定的装置的具体实例图。如图9所示,本例中,图8所示装置还可以包括:FIG. 9 is a view showing a specific example of an apparatus for synchronous display and positioning calibration of multi-contrast images according to an embodiment of the present invention. As shown in FIG. 9, in this example, the apparatus shown in FIG. 8 may further include:
操作同步模块901,用于根据鼠标指针在目标窗口图像上所做的操作,在其它各窗口中同步显示操作结果。 The operation synchronization module 901 is configured to synchronously display the operation result in the other windows according to the operation performed by the mouse pointer on the target window image.
综上所述,本发明实施例中根据多种对比度图像上的位置对比结果将多种对比度图像进行分窗口同步显示,避免了在多种对比度图像之间进行切换,或者通过多屏幕进行显示;本发明实施例中根据目标窗口图像上的鼠标指针位置及多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针,避免了医生通过肉眼进行对比,或者手动选择各图像同一位置进行对比;本发明实施例实施过程简单高效,并且能够很容易地实现精准比对,即使是高分辨率图像的对比,也不会给医生增加额外的难度。In summary, in the embodiment of the present invention, multiple contrast images are displayed in a window according to position comparison results on multiple contrast images, thereby avoiding switching between multiple contrast images or displaying through multiple screens; In the embodiment of the present invention, according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images, the corresponding position on the other window image is calculated and the virtual mouse pointer is displayed at the position, thereby preventing the doctor from comparing with the naked eye, or Manually selecting the same position of each image for comparison; the embodiment of the present invention is simple and efficient in implementation, and can accurately achieve accurate comparison, even if the contrast of high-resolution images does not add extra difficulty to the doctor.
进一步的,本发明实施例还提供了各窗口数据源的同步,不仅可以同步翻页,还可以准确同步定位不同窗口的组织位置,方便医生比较同一组织位置对应的各图像源中的表现。总之,本发明实施例提供了一种便于多窗口诊断、比较和测量的方案。Further, the embodiment of the present invention further provides synchronization of each window data source, which not only can synchronously turn pages, but also accurately synchronize the organization positions of different windows, so that the doctor can compare the performances in the image sources corresponding to the same tissue position. In summary, embodiments of the present invention provide a solution that facilitates multi-window diagnostics, comparison, and measurement.
本领域内的技术人员应明白,本发明的实施例可提供为方法、系统、或计算机程序产品。因此,本发明可采用完全硬件实施例、完全软件实施例、或结合软件和硬件方面的实施例的形式。而且,本发明可采用在一个或多个其中包含有计算机可用程序代码的计算机可用存储介质(包括但不限于磁盘存储器、CD-ROM、光学存储器等)上实施的计算机程序产品的形式。Those skilled in the art will appreciate that embodiments of the present invention can be provided as a method, system, or computer program product. Accordingly, the present invention may take the form of an entirely hardware embodiment, an entirely software embodiment, or a combination of software and hardware. Moreover, the invention can take the form of a computer program product embodied on one or more computer-usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) including computer usable program code.
本发明是参照根据本发明实施例的方法、设备(系统)、和计算机程序产品的流程图和/或方框图来描述的。应理解可由计算机程序指令实现流程图和/或方框图中的每一流程和/或方框、以及流程图和/或方框图中的流程和/或方框的结合。可提供这些计算机程序指令到通用计算机、专用计算机、嵌入式处理机或其他可编程数据处理设备的处理器以产生一个机器,使得通过计算机或其他可编程数据处理设备的处理器执行的指令产生用于实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能的装置。The present invention has been described with reference to flowchart illustrations and/or block diagrams of methods, apparatus (system), and computer program products according to embodiments of the invention. It will be understood that each flow and/or block of the flowchart illustrations and/or FIG. These computer program instructions can be provided to a processor of a general purpose computer, special purpose computer, embedded processor, or other programmable data processing device to produce a machine for the execution of instructions for execution by a processor of a computer or other programmable data processing device. Means for implementing the functions specified in one or more of the flow or in a block or blocks of the flow chart.
这些计算机程序指令也可存储在能引导计算机或其他可编程数据处理设备以特定方式工作的计算机可读存储器中,使得存储在该计算机可读存储器中的指令产生包括指令装置的制造品,该指令装置实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能。The computer program instructions can also be stored in a computer readable memory that can direct a computer or other programmable data processing device to operate in a particular manner, such that the instructions stored in the computer readable memory produce an article of manufacture comprising the instruction device. The apparatus implements the functions specified in one or more blocks of a flow or a flow and/or block diagram of the flowchart.
这些计算机程序指令也可装载到计算机或其他可编程数据处理设备上,使得在计算机或其他可编程设备上执行一系列操作步骤以产生计算机实现的处理,从而在计算机或其他可编程设备上执行的指令提供用于实现在流程图一个流程或多个流程和/或方框图一个方框或多个方框中指定的功能的步骤。 These computer program instructions can also be loaded onto a computer or other programmable data processing device such that a series of operational steps are performed on a computer or other programmable device to produce computer-implemented processing for execution on a computer or other programmable device. The instructions provide steps for implementing the functions specified in one or more of the flow or in a block or blocks of a flow diagram.
以上所述的具体实施例,对本发明的目的、技术方案和有益效果进行了进一步详细说明,所应理解的是,以上所述仅为本发明的具体实施例而已,并不用于限定本发明的保护范围,凡在本发明的精神和原则之内,所做的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。 The above described specific embodiments of the present invention are further described in detail, and are intended to be illustrative of the embodiments of the present invention. All modifications, equivalent substitutions, improvements, etc., made within the spirit and scope of the invention are intended to be included within the scope of the invention.

Claims (14)

  1. 一种多对比度图像同步显示和定位标定的方法,其特征在于,包括:A multi-contrast image synchronous display and positioning calibration method, comprising:
    获得生物体同一部位的多种对比度图像;Obtaining multiple contrast images of the same part of the organism;
    对所述多种对比度图像进行扫描位置信息提取和对比计算;Performing scanning position information extraction and comparison calculation on the plurality of contrast images;
    根据所述多种对比度图像上的位置对比结果将所述多种对比度图像进行分窗口同步显示;And displaying the plurality of contrast images in a window-by-window manner according to the position comparison result on the plurality of contrast images;
    将真实鼠标指针所在窗口作为目标窗口,根据目标窗口图像上的鼠标指针位置及所述多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。The window of the real mouse pointer is used as the target window, and the corresponding position on the other window image is calculated according to the position of the mouse pointer on the image of the target window and the position comparison result on the plurality of contrast images, and the virtual mouse pointer is displayed at the position.
  2. 如权利要求1所述的方法,其特征在于,对所述多种对比度图像进行扫描位置信息提取和对比计算,包括提取所述多种对比度图像的扫描层面位置信息和扫描层内位置信息,并进行对比计算偏差。The method according to claim 1, wherein the scanning position information extraction and the comparison calculation are performed on the plurality of contrast images, including extracting scan slice position information of the plurality of contrast images and position information in the scan layer, and Perform a comparison to calculate the deviation.
  3. 如权利要求2所述的方法,其特征在于,根据所述多种对比度图像上的位置对比结果将所述多种对比度图像进行分窗口同步显示,包括:The method of claim 2, wherein displaying the plurality of contrast images in a window-by-window manner according to a position comparison result on the plurality of contrast images comprises:
    若所述多种对比度图像上的位置比对结果表明所述多种对比度图像的扫描层面位置信息不同,则根据目标窗口图像的扫描层数及扫描层厚,其它窗口图像的扫描层厚,以及其它窗口图像与目标窗口图像的扫描位置偏差,查找其它窗口图像的临近层面并同步显示。If the position alignment result on the plurality of contrast images indicates that the scanning slice position information of the plurality of contrast images is different, the scanning layer thickness of the other window images according to the scanning layer number of the target window image and the scanning layer thickness, and The other window images are deviated from the scanning position of the target window image, and the adjacent layers of the other window images are searched for and displayed simultaneously.
  4. 如权利要求3所述的方法,其特征在于,按如下公式查找其它窗口图像的临近层面并同步显示:The method according to claim 3, wherein the adjacent layers of the other window images are searched for and displayed synchronously as follows:
    NX=Round[(ΔZX+M×S)/SX];N X = Round [(ΔZ X + M × S) / S X ];
    其中,NX为其它窗口图像的临近层面,ΔZX为其它窗口图像与目标窗口图像的扫描位置偏差;M为目标窗口图像的扫描层数;S为目标窗口图像的扫描层厚;SX为其它窗口图像的扫描层厚;Round[]表示四舍五入计算。Wherein, N X is the adjacent layer of the other window image, ΔZ X is the scanning position deviation of the other window image and the target window image; M is the scanning layer number of the target window image; S is the scanning layer thickness of the target window image; S X is Scanning layer thickness of other window images; Round[] indicates rounding calculation.
  5. 如权利要求2所述的方法,其特征在于,根据目标窗口图像上鼠标指针位置及所述多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针,包括:The method according to claim 2, wherein the corresponding position on the other window image is calculated and the virtual mouse pointer is displayed at the position according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images. include:
    若所述多种对比度图像上的位置对比结果表明所述多种对比度图像的扫描层内位置信息不同,则根据目标窗口图像上鼠标指针位置,以及其它窗口图像与目标窗口图像的层内位置偏差,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。 If the position comparison result on the plurality of contrast images indicates that the position information in the scanning layer of the plurality of contrast images is different, according to the position of the mouse pointer on the target window image, and the intra-layer position deviation of the other window image and the target window image , calculate the corresponding position on the other window image and display the virtual mouse pointer at that position.
  6. 如权利要求5所述的方法,其特征在于,按如下公式计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针:The method of claim 5 wherein the corresponding position on the other window image is calculated and the virtual mouse pointer is displayed at the position as follows:
    (X1,Y1)=(X+ΔX1,Y+ΔY1);(X 1 , Y 1 )=(X+ΔX 1 , Y+ΔY 1 );
    其中,(X1,Y1)为其它窗口图像上对应位置,(X,Y)为目标窗口图像上鼠标指针位置,(ΔX1,ΔY1)为其它窗口图像与目标窗口图像的层内位置偏差。Where (X 1 , Y 1 ) is the corresponding position on the other window image, (X, Y) is the position of the mouse pointer on the target window image, and (ΔX 1 , ΔY 1 ) is the intra-layer position of the other window image and the target window image. deviation.
  7. 如权利要求1至6任一项所述的方法,其特征在于,还包括:The method of any of claims 1 to 6, further comprising:
    根据鼠标指针在目标窗口图像上所做的操作,在其它各窗口中同步显示操作结果。The result of the operation is synchronized in the other windows according to the operation of the mouse pointer on the target window image.
  8. 一种多对比度图像同步显示和定位标定的装置,其特征在于,包括:A device for multi-contrast image synchronous display and positioning calibration, comprising:
    图像获得模块,用于获得生物体同一部位的多种对比度图像;An image obtaining module, configured to obtain a plurality of contrast images of the same part of the living body;
    位置对比模块,用于对所述多种对比度图像进行扫描位置信息提取和对比计算;a position comparison module, configured to perform scanning position information extraction and comparison calculation on the plurality of contrast images;
    图像显示模块,用于根据所述多种对比度图像上的位置对比结果将所述多种对比度图像进行分窗口同步显示;An image display module, configured to perform window-by-window synchronization display on the plurality of contrast images according to a position comparison result on the plurality of contrast images;
    定位标定模块,用于将真实鼠标指针所在窗口作为目标窗口,根据目标窗口图像上的鼠标指针位置及所述多种对比度图像上的位置对比结果,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。a positioning calibration module, configured to use a window of the real mouse pointer as a target window, and calculate a corresponding position on the other window image according to the position of the mouse pointer on the target window image and the position comparison result on the plurality of contrast images, and display the position on the other window image Virtual mouse pointer.
  9. 如权利要求8所述的装置,其特征在于,所述位置对比模块进一步用于:提取所述多种对比度图像的扫描层面位置信息和扫描层内位置信息,并进行对比计算偏差。The device according to claim 8, wherein the position comparison module is further configured to: extract scan slice position information of the plurality of contrast images and position information within the scan layer, and perform a comparison calculation deviation.
  10. 如权利要求9所述的装置,其特征在于,所述图像显示模块进一步用于:The apparatus according to claim 9, wherein said image display module is further configured to:
    若所述多种对比度图像上的位置比对结果表明所述多种对比度图像的扫描层面位置信息不同,则根据目标窗口图像的扫描层数及扫描层厚,其它窗口图像的扫描层厚,以及其它窗口图像与目标窗口图像的扫描位置偏差,查找其它窗口图像的临近层面并同步显示。If the position alignment result on the plurality of contrast images indicates that the scanning slice position information of the plurality of contrast images is different, the scanning layer thickness of the other window images according to the scanning layer number of the target window image and the scanning layer thickness, and The other window images are deviated from the scanning position of the target window image, and the adjacent layers of the other window images are searched for and displayed simultaneously.
  11. 如权利要求10所述的装置,其特征在于,所述图像显示模块进一步用于按如下公式查找其它窗口图像的临近层面并同步显示:The device according to claim 10, wherein the image display module is further configured to find adjacent layers of other window images and display them synchronously according to the following formula:
    NX=Round[(ΔZX+M×S)/SX];N X = Round [(ΔZ X + M × S) / S X ];
    其中,NX为其它窗口图像的临近层面,ΔZX为其它窗口图像与目标窗口图像的扫描位置偏差;M为目标窗口图像的扫描层数;S为目标窗口图像的扫描层厚;SX为其它窗口图像的扫描层厚;Round[]表示四舍五入计算。Wherein, N X is the adjacent layer of the other window image, ΔZ X is the scanning position deviation of the other window image and the target window image; M is the scanning layer number of the target window image; S is the scanning layer thickness of the target window image; S X is Scanning layer thickness of other window images; Round[] indicates rounding calculation.
  12. 如权利要求9所述的装置,其特征在于,所述定位标定模块进一步用于: The device according to claim 9, wherein said positioning calibration module is further configured to:
    若所述多种对比度图像上的位置对比结果表明所述多种对比度图像的扫描层内位置信息不同,则根据目标窗口图像上鼠标指针位置,以及其它窗口图像与目标窗口图像的层内位置偏差,计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针。If the position comparison result on the plurality of contrast images indicates that the position information in the scanning layer of the plurality of contrast images is different, according to the position of the mouse pointer on the target window image, and the intra-layer position deviation of the other window image and the target window image , calculate the corresponding position on the other window image and display the virtual mouse pointer at that position.
  13. 如权利要求12所述的装置,其特征在于,所述定位标定模块进一步用于按如下公式计算其它窗口图像上对应位置并在该位置显示虚拟鼠标指针:The apparatus according to claim 12, wherein said positioning calibration module is further configured to calculate a corresponding position on the other window image and display the virtual mouse pointer at the position according to the following formula:
    (X1,Y1)=(X+ΔX1,Y+ΔY1);(X 1 , Y 1 )=(X+ΔX 1 , Y+ΔY 1 );
    其中,(X1,Y1)为其它窗口图像上对应位置,(X,Y)为目标窗口图像上鼠标指针位置,(ΔX1,ΔY1)为其它窗口图像与目标窗口图像的层内位置偏差。Where (X 1 , Y 1 ) is the corresponding position on the other window image, (X, Y) is the position of the mouse pointer on the target window image, and (ΔX 1 , ΔY 1 ) is the intra-layer position of the other window image and the target window image. deviation.
  14. 如权利要求8至13任一项所述的装置,其特征在于,还包括:The device according to any one of claims 8 to 13, further comprising:
    操作同步模块,用于根据鼠标指针在目标窗口图像上所做的操作,在其它各窗口中同步显示操作结果。 The operation synchronization module is configured to synchronously display the operation result in other windows according to the operation of the mouse pointer on the target window image.
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