WO2017220310A1 - Personal care composition comprising retinoid and porous silica - Google Patents
Personal care composition comprising retinoid and porous silica Download PDFInfo
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- WO2017220310A1 WO2017220310A1 PCT/EP2017/063359 EP2017063359W WO2017220310A1 WO 2017220310 A1 WO2017220310 A1 WO 2017220310A1 EP 2017063359 W EP2017063359 W EP 2017063359W WO 2017220310 A1 WO2017220310 A1 WO 2017220310A1
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- porous silica
- retinyl
- skin
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0241—Containing particulates characterized by their shape and/or structure
- A61K8/0279—Porous; Hollow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/062—Oil-in-water emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/29—Titanium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/895—Polysiloxanes containing silicon bound to unsaturated aliphatic groups, e.g. vinyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Definitions
- the present invention relates to a personal care composition.
- the personal care composition comprises retinoid which is more stable over long-term storage and higher blurring efficacy.
- Retinoids e.g. retinol and retinyl esters
- Retinol vitamin A
- Natural and synthetic vitamin A derivatives have been used extensively in the treatment of a variety of skin disorders and have been used as skin repair or renewal agents.
- Retinoic acid has been employed to treat a variety of skin conditions, e.g., acne, wrinkles, psoriasis, age spots and discoloration.
- the viscosity of the composition may be affected after long-term storage at elevated temperature, perhaps due to the interaction of retinoids with the ingredients in the formulation.
- the present invention provides a personal care composition
- a personal care composition comprising retinoid, porous silica, silicone elastomer, and a cosmetically acceptable carrier.
- the present invention provides a method of reducing the appearance of fine lines, wrinkles, pores and/or blemish spots; evening skin tone, or a combination thereof on skin comprising the step of applying a composition of the present invention on the desired skin surface.
- the present invention provides use of composition of the present invention for reducing the appearance of fine lines, wrinkles, pores and/or blemish spots; evening skin tone, or a combination thereof on the desired skin surface.
- the method and use of the composition of the present invention are preferably for non-therapeutic benefits. All other aspects of the present invention will more readily become apparent upon considering the detailed description and examples which follow.
- Silicone elastomer refers to deformable organopolysiloxane with viscoelastic properties.
- Specific surface area refers to specific surface area determined according to Brunauer-Emmett-Teller method. The value of the specific surface area may be measured by following ASTM standard D 3663-78.
- Diameter refers to particle diameter in non-aggregated state unless otherwise stated.
- diameter means the z-average diameter measured, for example, using dynamic light scattering (see international standard ISO 13321 ) with an instrument such as a Zetasizer NanoTM (Malvern Instruments Ltd, UK) unless otherwise stated.
- diameter means the apparent volume median diameter (D50, also known as x50 or sometimes d(0.5)) of the particles measurable for example, by laser diffraction using a system (such as a MastersizerTM 2000 available from Malvern Instruments Ltd) meeting the requirements set out in ISO 13320 unless otherwise stated.
- D50 apparent volume median diameter
- x50 also known as x50 or sometimes d(0.5)
- the composition of the present invention comprises a retinoid.
- the retinoid is selected from retinyl ester, retinol, retinal, retinoic acid or a mixture thereof. More preferably the retinoid comprises retinol, retinyl ester, or a mixture thereof and even more preferably the retinoid is selected from retinol, retinyl ester, or a mixture thereof.
- retinol includes the following isomers of retinol: all-trans-retinol, 13-cis-retinol, 1 1 -cis-retinol, 9-cis-retinol, 3,4-didehydro-retinol, 3, 4-didehydro-13-cis-retinol; 3,4- didehydro-1 1 -cis-retinol; 3,4-didehydro-9-cis-retinol.
- Preferred isomers are all-trans- retinol, 13-cis-retinol, 3,4-didehydro-retinol, 9-cis-retinol.
- Most preferred retinol is all- trans-retinol, due to its wide commercial availability.
- Retinyl ester is an ester of retinol.
- the term "retinol" has been defined above.
- Retinyl esters suitable for use in the present invention are preferably C1-C30 esters of retinol, more preferably C2-C20 esters of retinol, and most preferably C2, C3, and C16 esters of retinol.
- retinyl esters include but are not limited to: retinyl palmitate, retinyl formate, retinyl acetate, retinyl propionate, retinyl butyrate, retinyl valerate, retinyl isovalerate, retinyl hexanoate, retinyl heptanoate, retinyl octanoate, retinyl nonanoate, retinyl decanoate, retinyl undecanoate, retinyl laurate, retinyl tridecanoate, retinyl myristate, retinyl pentadecanoate, retinyl heptadecanoate, retinyl stearate, retinyl isostearate, retinyl nonadecanoate, retinyl arachidonate, retinyl behenate, retin
- the retinyl ester for use in the present invention is preferably selected from retinyl palmitate, retinyl acetate, retinyl linoleate, retinyl oleate, retinyl propionate or a mixture thereof. More preferably the retinyl ester is selected from retinyl palmitate, retinyl acetate, retinyl propionate, or a mixture thereof. Most preferably the retinyl ester is selected from retinyl palmitate, retinyl propionate, or a mixture thereof.
- Particularly preferred retinoid is selected from all-trans-retinol, retinyl palmitate, retinyl acetate, retinyl propionate, or a mixture thereof. Most preferably the retinoid is selected from retinyl palmitate, retinyl propionate, or a mixture thereof.
- retinoid is employed in the composition in an amount of 0.0001 % to 5% by weight of the composition, more preferably in an amount of 0.0005% to 3%, even more preferably from 0.001 to 0.5% and most preferably in an amount of 0.01 % to 0.2% by weight of the composition.
- the porous silica is preferably non-fumed silica.
- the porous silica is hydrophilic. Even more preferably the porous silica is unmodified porous silica microsphere.
- Hydrophilic porous silica as used herein refers to silica having a water absorption value of greater than 10g of water/1 OOg of particle measured in same manner as described in ASTM Method D281 -84 but using water instead of oil.
- Microsphere refers to spherical particle having average diameter of 0.1 to 50 microns, more preferably from 1 to 15 microns.
- the specific surface area of the porous silica is preferably at least 300 m 2 /g, more preferably from 400 to 1000 m 2 /g, even more preferably from 550 to 880 m 2 /g and most preferably from 590 to 810 m 2 /g.
- the porous silica has the capability of absorbing large amounts of oils.
- the porous silica is a porous silica microsphere having an oil absorption value of higher than 100g/100g, more preferably higher than 200g/100g and even more preferably higher than 280g/100g.
- the oil absorption value refers to the values measured in conformity with ASTM Method D281 -84.
- the porous silica preferably has an average diameter of 200 nm to 40 microns, more preferably from 0.6 to 25 microns, even more preferably from 1 to 20 microns, still even more preferably from 1 .5 to 12 microns and most preferably from 2 to 5 microns.
- the porous silica is preferably substantially uniform in size which means less than 5% of the porous silica have a diameter less than 0.5 times the average diameter and less than 5% of the porous silica have a diameter greater than 1.5 times the average diameter.
- the range of the diameter of the porous silica is preferably 0.8 to 1.2 times the average diameter, more preferably 0.9 to 1.1 times the average diameter.
- Particularly preferred porous silica includes MSS-500/3H, MSS-500/H from Kobo Products Inc.
- the porous silica is preferably present in amount of 0.01 to 20% by weight of the composition, more preferably from 0.05 to 14%, even more preferably from 0.2 to 9%, still even more preferably from 0.4 to 5% and most preferably from 0.8 to 2% by weight of the composition.
- the composition comprises a silicone elastomer.
- the silicone elastomer used in the present invention is preferably powder of silicone elastomer. It is highly preferred that the silicone elastomer is cross-linked.
- the silicone elastomer can be obtained from curable organo-polysiloxanes.
- addition reaction-curing organopolysiloxane compositions which cure under platinum metal catalysis by the addition reaction between SiH-containing diorganopolysiloxane and organopolysiloxane having silicon-bonded vinyl groups; condensation-curing organopolysiloxane compositions which cure in the presence of an organotin compound by a dehydrogenation reaction between hydroxyl terminated diorganopolysiloxane and SiH-containing diorganopolysiloxane; condensation-curing organopolysiloxane compositions which cure in the presence of an organotin compound or a titanate ester, by a condensation reaction between a hydroxyl terminated diorganopolysiloxane and a hydrolyzable organosilane (this condensation reaction is exemplified by dehydration, alcohol-liberating, oxime-liberating, amine-liberating, amide-liberating, carboxyl- liberating, and ketone-liber
- the silicone elastomer is preferably obtained by addition reaction-curing organopolysiloxane compositions which cure under platinum metal catalysis by the addition reaction between SiH-containing diorganopolysiloxane and organopolysiloxane having silicon-bonded vinyl groups
- the silicone elastomer may either be an emulsifying or non-emulsifying cross-linked silicone elastomer or a combination thereof but preferably the silicone elastomer is non- emulsifying.
- non-emulsifying defines cross-linked silicone elastomer from which poly-oxyalkylene units are absent.
- emulsifying means cross-linked organo-polysiloxane elastomer having at least one poly- oxyalkylene (e.g., poly-oxyethylene or poly-oxypropylene) unit.
- Preferred silicone elastomers are organo-polysiloxanes available under the INCI names of dimethicone/vinyl dimethicone crosspolymer, dimethicone crosspolymer and Polysilicone-1 1. More preferably the silicone elastomer is dimethicone/vinyl dimethicone crosspolymer.
- the average diameter of the silicone elastomer is from 0.2 to 50 microns, more preferably from 0.5 to 20 microns, even more preferably from 0.8 to 10 microns, and still even more preferably from 1 .5 to 6 microns.
- the silicone elastomer is preferably present in amount of 0.01 to 25%, more preferably 0.1 to 20%, even more preferably 1 to 15%, still even more preferably 3 to 12%, and most preferably from 6 to 10% by weight of the composition.
- the weight ratio of silicone elastomer to the porous silica is preferably from 1 :2 to 40:1 , more preferably from 2:1 to 20:1 and even more preferably from 3:1 to 10:1 .
- the composition may additionally comprises boron nitride.
- the boron nitride is preferably turbostratic boron nitride.
- turbostratic boron nitride refers to boron nitride having oxygen impurity in the boron nitride crystal lattice.
- the turbostratic boron nitride has an average diameter in the range of 200 nm to 100 microns, more preferably 500 nm to 50 microns, even more preferably from 1 to 15 microns, still even more preferably from 3 to 12 microns and most preferably from 4 to 9 microns.
- the specific surface area of the turbostratic boron nitride is preferably from 5 to 80 m 2 /g, more preferably from 10 to 60 m 2 /g and even more preferably from 15 to 40 m 2 /g.
- the content of oxygen in the turbostratic boron nitride is preferably at least 0.2% by mole of the turbostratic boron nitride, more preferably from 0.5 to 3%, even more preferably from 1 to 2%, and most preferably from 1 .2 to 1.8% by mole of the turbostratic boron nitride.
- turbostratic boron nitride is Softouch * Boron Nitride Powder CC6097 from Momentive.
- the boron nitride may be present in amount of 0.01 to 15% by weight of the composition, more preferably 0.1 to 12%, even more preferably from 0.4 to 8%, still even more preferably from 1 to 5% and most preferably from 2 to 4% by weight of the composition.
- the composition additionally comprises a whitening pigment.
- Whitening pigments are typically particles of high refractive index materials.
- the whitening pigment may have a refractive index of greater than 1 .3, more preferably greater than 1 .8 and most preferably from 2.0 to 2.7.
- whitening pigment examples include those comprising bismuth oxy-chloride, boron nitride, barium sulfate, mica, silica, titanium dioxide, zirconium oxide, aluminium oxide, zinc oxide or combinations thereof. More preferred whitening pigment are particles comprising titanium dioxide, zinc oxide, zirconium oxide, mica, iron oxide or a combination thereof. Even more preferred whitening pigment are particles comprising zinc oxide, zirconium oxide, titanium dioxide or a combination thereof as these materials have especially high refractive index. Still even more preferably the whitening pigment is selected from titanium dioxide, zinc oxide or a mixture thereof and Most preferred whitening pigment is titanium dioxide.
- the average diameter of whitening pigment is typical from 15 nm to 2 microns, more preferably from 35 nm to 800 nm, even more preferably from 50 nm to 500 nm and still even more preferably from 100 to 300 nm.
- the composition comprises whitening pigment in an amount of from 0.001 to 10%, more preferably 0.01 to 6%, more preferably still 0.1 to 3% and most preferably 0.2 to 2% by weight of the composition.
- the composition preferably additionally comprises one or more organic sunscreens.
- organic sunscreen is suitable for use in combination with the essential ingredients of this invention.
- Suitable UV-A / UV-B sunscreen include, 2- hydroxy-4- methoxybenzophenone, octyldimethyl p-aminobenzoic acid, digalloyltrioleate, 2,2- dihydroxy-4-methoxybenzophenone, ethyl-4-(bis(hydroxypropyl)) aminobenzoate, 2- ethylhexyl-2-cyano-3,3-diphenylacrylate, 2-ethylhexylsalicylate, glyceryl p- aminobenzoate, 3,3,5-trimethylcyclohexylsalicylate, methylanthranilate, p-dimethyl- aminobenzoic acid or aminobenzoate, 2-ethylhexyl-p-dimethyl- amino-benzoate, 2- phenylbenzimidazole-5-s
- the most suitable organic sunscreens are 2-ethylhexyl-p-methoxycinnamate, butylmethoxydibenzoylmethane or a mixture thereof.
- a safe and effective amount of organic sunscreen may be used in the compositions useful in the subject invention.
- the composition preferably comprises from 0.1 % to 10%, more preferably from 0.1 % to 5%, of organic sunscreen by weight of the composition.
- the composition of the invention preferably comprises a skin lightening agent.
- Vitamin B3 compounds (including derivatives of vitamin B3) e.g. niacin, nicotinic acid or niacinamide are the preferred skin lightening agent as per the invention, most preferred being niacinamide.
- Vitamin B3 compounds, when used, are preferably present in an amount in the range of 0.1 to 10%, more preferably 0.2 to 5% by weight of the composition.
- compositions of the present invention will also include a cosmetically acceptable carrier.
- the carrier will be (or at least comprise) a water and oil emulsion, which in certain embodiments may be water-in-oil emulsion.
- Preferred emulsions are the oil-in-water variety.
- Preferred hydrophobic material for use in the oil phase of such emulsions includes emollients such as fats, oils, fatty alcohols, fatty acids, soaps, silicone oils, synthetic esters and/or hydrocarbons.
- Silicone oils may be divided into the volatile and nonvolatile variety. Volatile silicone oils (if used) are preferably chosen from cyclic (cyclomethicone) or linear polydimethylsiloxanes containing from 3 to 9, preferably from 4 to 5, silicon atoms.
- Nonvolatile silicone oils useful as an emollient material include polyalkyl siloxanes, polyalkylaryl siloxanes and polyether siloxane copolymers.
- the essentially nonvolatile polyalkyl siloxanes useful herein include, for example, polydimethyl siloxanes with viscosities of from about 5 x 10 "6 to 0.1 m 2 /s at 25 °C.
- the preferred nonvolatile emollients useful in the present compositions are the polydimethyl siloxanes having viscosities from about 1 x 10 "s to about 4 X 10 "4 m 2 /s at 25 °C.
- non-silicone emollients include stearyl alcohol, glyceryl monoricinoleate, mink oil, cetyl alcohol, isopropyl isostearate, stearic acid, isobutyl palmitate, isocetyl stearate, oleyl alcohol, isopropyl laurate, hexyl laurate, decyl oleate, octadecan-2-ol, isocetyl alcohol, eicosanyl alcohol, behenyl alcohol, cetyl palmitate, di- n- butyl sebacate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, butyl stearate, polyethylene glycol, triethylene glycol, lanolin, cocoa butter, corn oil, cotton seed oil, olive oil, palm kernel oil, rape seed oil, safflower seed oil, evening primrose oil, soybean oil, sunflower seed oil, avocado oil
- ester emollients are: a) Alkenyl or alkyl esters of fatty acids having 10 to 20 carbon atoms. Examples thereof include isoarachidyl neopentanoate, isodecyl neopentanoate, isononyl isonanoate, cetyl ricinoleate, oleyl myristate, oleyl stearate, and oleyl oleate; b) Ether-esters such as fatty acid esters of ethoxylated fatty alcohols; c) Polyhydric alcohol esters.
- pentaerythritol, trimethylolpropane and neopentyl glycol esters of C1-C30 alcohols are particularly useful.
- pentaerythrityl tetraethylhexanoate is particularly useful.
- Wax esters such as beeswax, spermaceti wax and tribehenin wax;
- f) Sugar ester of fatty acids such as sucrose polybehenate and sucrose polycottonseedate; or g) mixtures of two or more of the foregoing (a) to (f).
- Hydrocarbons which are suitable emollients include petrolatum, mineral oil, C11-C13 isoparaffins, polyalphaolefins, isohexadecane or a mixture thereof.
- Amounts of water in the carrier may, for example, range from 1 to 99%, more preferably from 5 to 90%, even more preferably from 35 to 80%, optimally between 40 and 70% by weight of the personal care composition.
- compositions which can be included in the cosmetically acceptable carrier include solvents, humectants, thickeners and powders.
- the personal care composition has a L&W (line and wrinkle) index of at least 0%. More preferably the personal care composition has a L&W index of 10% to 300%. Even more preferably, the personal care composition has a L&W index of 20% to 150%. The measurements of L&W index is described in Example 2.
- the personal care composition of this invention is preferably a skin care composition. More preferably, the composition is preferably an antiperspirant composition or a face (except eye lids and lips) care composition.
- the skin care composition refers to a composition suitable for topical application to human skin, including leave-on and wash- off products. Preferably the term encompasses a fluid liquid, and particularly a moisturizer rather than a make-up product. Most preferred are leave-on compositions.
- leave-on as used with reference to compositions herein means a composition that is applied to or rubbed on the skin, and left thereon.
- wash-off means a skin cleanser that is applied to or rubbed on the skin and rinsed off substantially immediately subsequent to application.
- skin as used herein includes the skin on the face (except eye lids and lips), neck, chest, abdomen, back, arms, under arms, hands, and legs.
- skin includes the skin on the face (except eye lids and lips) and under arms. More preferably skin means skin on the face other than lips and eyelids.
- composition can be formulated in any known format, more preferred formats being creams or lotions.
- Packaging for the composition of this invention can be a jar or tube as well as any other format typically seen for cosmetic, cream, washing and lotion type products.
- the compositions may be applied topically and preferably 1-4 milligrams of composition is applied per square centimeter of skin.
- composition of the invention preferably delivers a cosmetic benefit to the skin of an individual to which it is topically applied.
- cosmetic benefits include reducing the appearance of fine lines, wrinkles, pores and/or blemish spots; evening skin tone, or a combination thereof on the desired skin surface.
- This example demonstrated the preparation of skin care compositions.
- composition of the present invention had less viscosity change after long-term storage.
- the samples were packaged into identical transparent jars with equal amount. These packaged samples were placed into cabinets with pre-set temperatures of 50 °C for three months.
- the viscosity of the samples before and after storage were measured at 25 °C by stress-controlled MCR 501 rheometer (Anton Paar, Physica MCR501 , Austria), fitted with a sandblast parallel geometry (PP25s), at shear rate 3.98 1/s.
- the Viscosity Maintenance Rate was calculated by (Viscosity of sample after storage)/(Viscosity of sample before storage) x100%.
- Table 2 shows the Viscosity Maintenance Rate of the samples after storage for three months at 50 °C. It was surprisingly found that the composition containing retinyl propionate had less viscosity change after storage for three months by incorporating both porous silica and silicone elastomer (Sample 1 ) as compared to compositions incorporating either silicone elastomer alone or porous silica alone (Samples B and C).
- Wrinkled Bio-skin plates (BP-EW1 #BSC, Beaulax Co., Ltd., Tokyo, Japan) made of polyurethane elastomer were used as substrate to mimic the human skin with wrinkles.
- a dual-polarized image system called SAMBA (Bossa Nova Technologies, USA) was employed to measure the gloss degree of the wrinkled Bio-skin plates by following the method and principle described by Akira Matsubara [Skin translucency: what is it and how is it measured, The International Federation of Societies of Cosmetic Chemists (IFSCC) Congress 2006, Osaka, Japan].
- a software named SAMBA face system (Version 4.3) was equipped for the analysis.
- the Wrinkled Bio-skin plates were tested against an incident light with exposure time of 80 msec.
- the operation mode was parallel polarization and crossed polarization modes.
- Example 1 28 mg of one sample as prepared in Example 1 was applied to and spread by finger cot within the circle with area of 7 cm 2 for gloss test and the sample was allowed to dry naturally for 30 minutes.
- the gloss of the wrinkled Bio skin plates after the samples were applied were measured again using the SAMBA system.
- the incident light was reflected and scattered by Bio-skin plates.
- the specular reflected light kept the same polarization as the incident light whereas the scattering light from the volume (diffused light) was un-polarized.
- the SAMBA camera acquired successively two images corresponding to two states of polarization (parallel and crossed).
- the parallel image intensity (P) is contributed from both the reflected and scattered light
- the crossed image intensity (C) is contributed from the scattered light only.
- the parallel image plus the crossed image is equal to the total image delivered by a traditional camera or perceived by human eye.
- the gloss degree was calculated by (P-C)/(P+C). The calculation of gloss degree was performed for each pixel.
- the standard deviation (STD) of gloss degree is a measure of the uniformity of the skin appearance. The higher the STD is, the lower the uniformity is.
- STD standard deviation
- L&W index was calculated by (STD of gloss degree before applying sample - STD of gloss degree after applying sample)/( STD of gloss degree before applying sample). The higher the L&W index is, the higher is the blurring efficacy of the sample.
- Table 3 shows the test results of the L&W index. It was surprisingly found that the composition of the present invention had higher blurring efficacy. It was also surprisingly found that the presence of both silicone elastomer and porous silica was capable of synergistically boosting the blurring efficacy (Sample 1 vs. Sample B and C).
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Abstract
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Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201780038697.3A CN109310591A (en) | 2016-06-21 | 2017-06-01 | Personal care composition |
US16/309,647 US20190125649A1 (en) | 2016-06-21 | 2017-06-01 | Personal care composition comprising retinoid and porous silica |
MX2018015523A MX2018015523A (en) | 2016-06-21 | 2017-06-01 | Personal care composition comprising retinoid and porous silica. |
JP2018566498A JP7085085B2 (en) | 2016-06-21 | 2017-06-01 | Personal care composition containing retinoids and porous silica |
EP17726335.7A EP3471689B1 (en) | 2016-06-21 | 2017-06-01 | Personal care composition comprising retinoid and porous silica |
BR112018074660-6A BR112018074660A2 (en) | 2016-06-21 | 2017-06-01 | personal care composition, method for reducing the appearance of fine lines, wrinkles, pores and / or blemishes and use of a composition |
ZA2018/07870A ZA201807870B (en) | 2016-06-21 | 2018-11-21 | Personal care composition comprising retinoid and porous silica |
PH12018502481A PH12018502481A1 (en) | 2016-06-21 | 2018-11-26 | Personal care composition |
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Application Number | Priority Date | Filing Date | Title |
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CN2016086526 | 2016-06-21 | ||
CNPCT/CN2016/086526 | 2016-06-21 | ||
EP16184941.9 | 2016-08-19 | ||
EP16184941 | 2016-08-19 |
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WO2017220310A1 true WO2017220310A1 (en) | 2017-12-28 |
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PCT/EP2017/063359 WO2017220310A1 (en) | 2016-06-21 | 2017-06-01 | Personal care composition comprising retinoid and porous silica |
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US (1) | US20190125649A1 (en) |
EP (1) | EP3471689B1 (en) |
JP (1) | JP7085085B2 (en) |
CN (1) | CN109310591A (en) |
BR (1) | BR112018074660A2 (en) |
MX (1) | MX2018015523A (en) |
PH (1) | PH12018502481A1 (en) |
WO (1) | WO2017220310A1 (en) |
ZA (1) | ZA201807870B (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019105685A1 (en) | 2017-11-30 | 2019-06-06 | Unilever N.V. | Cosmetic composition for blurring surface imperfections of skin |
WO2020025290A1 (en) * | 2018-08-03 | 2020-02-06 | Unilever N.V. | Skin care composition |
WO2020136001A1 (en) | 2018-12-28 | 2020-07-02 | Unilever N.V. | A novel process and cosmetic composition for gloss and blur |
WO2020234038A1 (en) | 2019-05-21 | 2020-11-26 | Unilever N.V. | Cosmetic compositions for soft-focus |
WO2023110410A1 (en) | 2021-12-15 | 2023-06-22 | Unilever Ip Holdings B.V. | A skin care composition |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2021197802A1 (en) * | 2020-03-31 | 2021-10-07 | Unilever Ip Holdings B.V. | Topical composition based on porous particles and a crosspolymer comprising adipic acid and neopentylglycol |
MX2022014011A (en) * | 2020-05-09 | 2022-11-30 | Unilever Ip Holdings B V | Personal care composition with visually distinct aqueous and oil phase. |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10120525A (en) * | 1996-10-23 | 1998-05-12 | Shiseido Co Ltd | W/o-type emulsion cosmetic |
DE102004039631A1 (en) * | 2004-08-11 | 2006-03-02 | Lancaster Group Gmbh | Pigment containing cosmetic agent, useful for anti-folding treatment of human skin, comprises active complex, carrier material, auxiliary material, and optionally further active agent |
DE102006013925A1 (en) * | 2006-03-21 | 2007-09-27 | Lancaster Group Gmbh | Cosmetic for the sustainable treatment of deeper skin folds |
US20130059021A1 (en) * | 2011-02-16 | 2013-03-07 | Oxygen Biotherapeutics, Inc. | Perfluoro(n-butylcyclohexane) compositions and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003292415A (en) | 2002-04-01 | 2003-10-15 | Shin Etsu Chem Co Ltd | Cosmetic |
JP2004143161A (en) | 2002-10-01 | 2004-05-20 | Kose Corp | Cosmetic |
ES2747926T3 (en) * | 2004-09-27 | 2020-03-12 | Special Water Patents B V | Methods and compositions for water treatment |
US20090081316A1 (en) * | 2007-09-20 | 2009-03-26 | Momentive Performance Materials Inc. | Boron nitride-containing silicone gel composition |
TWI468185B (en) * | 2007-12-27 | 2015-01-11 | Avon Prod Inc | Gel technology suitable for use in cosmetic compositions |
JP5571913B2 (en) | 2009-07-17 | 2014-08-13 | 株式会社 資生堂 | Oil-in-water emulsified skin cosmetic |
-
2017
- 2017-06-01 BR BR112018074660-6A patent/BR112018074660A2/en not_active Application Discontinuation
- 2017-06-01 WO PCT/EP2017/063359 patent/WO2017220310A1/en active Search and Examination
- 2017-06-01 EP EP17726335.7A patent/EP3471689B1/en active Active
- 2017-06-01 MX MX2018015523A patent/MX2018015523A/en active IP Right Grant
- 2017-06-01 US US16/309,647 patent/US20190125649A1/en not_active Abandoned
- 2017-06-01 JP JP2018566498A patent/JP7085085B2/en active Active
- 2017-06-01 CN CN201780038697.3A patent/CN109310591A/en active Pending
-
2018
- 2018-11-21 ZA ZA2018/07870A patent/ZA201807870B/en unknown
- 2018-11-26 PH PH12018502481A patent/PH12018502481A1/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10120525A (en) * | 1996-10-23 | 1998-05-12 | Shiseido Co Ltd | W/o-type emulsion cosmetic |
DE102004039631A1 (en) * | 2004-08-11 | 2006-03-02 | Lancaster Group Gmbh | Pigment containing cosmetic agent, useful for anti-folding treatment of human skin, comprises active complex, carrier material, auxiliary material, and optionally further active agent |
DE102006013925A1 (en) * | 2006-03-21 | 2007-09-27 | Lancaster Group Gmbh | Cosmetic for the sustainable treatment of deeper skin folds |
US20130059021A1 (en) * | 2011-02-16 | 2013-03-07 | Oxygen Biotherapeutics, Inc. | Perfluoro(n-butylcyclohexane) compositions and uses thereof |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019105685A1 (en) | 2017-11-30 | 2019-06-06 | Unilever N.V. | Cosmetic composition for blurring surface imperfections of skin |
WO2020025290A1 (en) * | 2018-08-03 | 2020-02-06 | Unilever N.V. | Skin care composition |
WO2020136001A1 (en) | 2018-12-28 | 2020-07-02 | Unilever N.V. | A novel process and cosmetic composition for gloss and blur |
US11779525B2 (en) | 2018-12-28 | 2023-10-10 | Conopco, Inc. | Process and cosmetic composition for gloss and blur |
WO2020234038A1 (en) | 2019-05-21 | 2020-11-26 | Unilever N.V. | Cosmetic compositions for soft-focus |
WO2023110410A1 (en) | 2021-12-15 | 2023-06-22 | Unilever Ip Holdings B.V. | A skin care composition |
Also Published As
Publication number | Publication date |
---|---|
JP2019518762A (en) | 2019-07-04 |
EP3471689A1 (en) | 2019-04-24 |
PH12018502481B1 (en) | 2019-03-25 |
US20190125649A1 (en) | 2019-05-02 |
MX2018015523A (en) | 2019-03-18 |
CN109310591A (en) | 2019-02-05 |
JP7085085B2 (en) | 2022-06-16 |
EP3471689B1 (en) | 2020-08-19 |
BR112018074660A2 (en) | 2019-03-06 |
ZA201807870B (en) | 2020-05-27 |
PH12018502481A1 (en) | 2019-03-25 |
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