WO2017220050A3 - Azithromycin pharmaceutical composition and medical use thereof for cough relief - Google Patents

Azithromycin pharmaceutical composition and medical use thereof for cough relief Download PDF

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Publication number
WO2017220050A3
WO2017220050A3 PCT/CN2017/097788 CN2017097788W WO2017220050A3 WO 2017220050 A3 WO2017220050 A3 WO 2017220050A3 CN 2017097788 W CN2017097788 W CN 2017097788W WO 2017220050 A3 WO2017220050 A3 WO 2017220050A3
Authority
WO
WIPO (PCT)
Prior art keywords
azithromycin
cough
pharmaceutical composition
medical use
inflammatory
Prior art date
Application number
PCT/CN2017/097788
Other languages
French (fr)
Chinese (zh)
Other versions
WO2017220050A2 (en
Inventor
崔坤峰
Original Assignee
赵吉永
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 赵吉永 filed Critical 赵吉永
Publication of WO2017220050A2 publication Critical patent/WO2017220050A2/en
Publication of WO2017220050A3 publication Critical patent/WO2017220050A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A61K36/8884—Arisaema, e.g. Jack in the pulpit

Abstract

Disclosed are an azithromycin pharmaceutical composition and a medical use thereof for cough relief. The azithromycin pharmaceutical composition contains azithromycin and a natural product compound (I) separated from dried rhizoma arisaematis and having a novel structure. When used individually, the azithromycin and the natural product compound (I) have an anti-inflammatory and cough-relieving effect. When used together, the two further improve the anti-inflammatory and cough-relieving effect, may be developed into an anti-inflammatory and cough-relieving drug, and have prominent substantive features and represent notable progress with respect to the prior art.
PCT/CN2017/097788 2016-06-23 2017-08-17 Azithromycin pharmaceutical composition and medical use thereof for cough relief WO2017220050A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201610463311.0 2016-06-23
CN201610463311.0A CN106146601A (en) 2016-06-23 2016-06-23 The pharmaceutical composition of azithromycin and the medical usage of cough-relieving thereof

Publications (2)

Publication Number Publication Date
WO2017220050A2 WO2017220050A2 (en) 2017-12-28
WO2017220050A3 true WO2017220050A3 (en) 2018-02-15

Family

ID=57353752

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2017/097788 WO2017220050A2 (en) 2016-06-23 2017-08-17 Azithromycin pharmaceutical composition and medical use thereof for cough relief

Country Status (2)

Country Link
CN (1) CN106146601A (en)
WO (1) WO2017220050A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105837449A (en) * 2016-04-18 2016-08-10 镇江高海生物药业有限公司 Pharmaceutical composition for L-tert-leucine and application thereof in biological medicine
CN105884741A (en) * 2016-04-23 2016-08-24 徐挺 Drug composition of bisoprolol fumarate and pharmaceutical application thereof
CN106146601A (en) * 2016-06-23 2016-11-23 崔坤峰 The pharmaceutical composition of azithromycin and the medical usage of cough-relieving thereof
CN106045835A (en) * 2016-06-23 2016-10-26 崔坤峰 Benserazide hydrochloride medicine composition and medical purpose therefore for decreasing blood glucose

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104107358A (en) * 2014-07-21 2014-10-22 河南科技大学第一附属医院 Pill used for relieving cough and reducing sputum and preparation method thereof
CN105663138A (en) * 2016-04-23 2016-06-15 贺玉皓 Clonazepam medicinal composition and medicinal application thereof
CN105837449A (en) * 2016-04-18 2016-08-10 镇江高海生物药业有限公司 Pharmaceutical composition for L-tert-leucine and application thereof in biological medicine
CN105884741A (en) * 2016-04-23 2016-08-24 徐挺 Drug composition of bisoprolol fumarate and pharmaceutical application thereof
CN106146601A (en) * 2016-06-23 2016-11-23 崔坤峰 The pharmaceutical composition of azithromycin and the medical usage of cough-relieving thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104107358A (en) * 2014-07-21 2014-10-22 河南科技大学第一附属医院 Pill used for relieving cough and reducing sputum and preparation method thereof
CN105837449A (en) * 2016-04-18 2016-08-10 镇江高海生物药业有限公司 Pharmaceutical composition for L-tert-leucine and application thereof in biological medicine
CN105663138A (en) * 2016-04-23 2016-06-15 贺玉皓 Clonazepam medicinal composition and medicinal application thereof
CN105884741A (en) * 2016-04-23 2016-08-24 徐挺 Drug composition of bisoprolol fumarate and pharmaceutical application thereof
CN106146601A (en) * 2016-06-23 2016-11-23 崔坤峰 The pharmaceutical composition of azithromycin and the medical usage of cough-relieving thereof

Also Published As

Publication number Publication date
WO2017220050A2 (en) 2017-12-28
CN106146601A (en) 2016-11-23

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