WO2017213893A1 - Ensemble d'ancrage de suture pour l'administration d'un agent thérapeutique - Google Patents

Ensemble d'ancrage de suture pour l'administration d'un agent thérapeutique Download PDF

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Publication number
WO2017213893A1
WO2017213893A1 PCT/US2017/034712 US2017034712W WO2017213893A1 WO 2017213893 A1 WO2017213893 A1 WO 2017213893A1 US 2017034712 W US2017034712 W US 2017034712W WO 2017213893 A1 WO2017213893 A1 WO 2017213893A1
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WO
WIPO (PCT)
Prior art keywords
anchor body
assembly
delivery system
shaft
therapeutic agent
Prior art date
Application number
PCT/US2017/034712
Other languages
English (en)
Inventor
Umasuthan SRIKUMARAN
Geoffrey I. Karasic
George Barnes
Matthew Koski
Mark HOUSMAN
Original Assignee
Smith & Nephew, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith & Nephew, Inc. filed Critical Smith & Nephew, Inc.
Publication of WO2017213893A1 publication Critical patent/WO2017213893A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
    • A61B17/8811—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it characterised by the introducer tip, i.e. the part inserted into or onto the bone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8802—Equipment for handling bone cement or other fluid fillers
    • A61B17/8805—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it
    • A61B17/8816—Equipment for handling bone cement or other fluid fillers for introducing fluid filler into bone or extracting it characterised by the conduit, e.g. tube, along which fluid flows into the body or by conduit connections
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A61B17/864—Pins or screws or threaded wires; nuts therefor hollow, e.g. with socket or cannulated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A61B17/8645—Headless screws, e.g. ligament interference screws
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/84—Fasteners therefor or fasteners being internal fixation devices
    • A61B17/86—Pins or screws or threaded wires; nuts therefor
    • A61B17/869—Pins or screws or threaded wires; nuts therefor characterised by an open form, e.g. wire helix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/8875—Screwdrivers, spanners or wrenches
    • A61B17/8877—Screwdrivers, spanners or wrenches characterised by the cross-section of the driver bit
    • A61B17/888—Screwdrivers, spanners or wrenches characterised by the cross-section of the driver bit the driver bit acting on the central region of the screw head
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0409—Instruments for applying suture anchors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/044—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors with a threaded shaft, e.g. screws
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/044—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors with a threaded shaft, e.g. screws
    • A61B2017/0441—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors with a threaded shaft, e.g. screws the shaft being a rigid coil or spiral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0445—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors cannulated, e.g. with a longitudinal through-hole for passage of an instrument
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
    • A61B2017/0448—Additional elements on or within the anchor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/04—Surgical instruments, devices or methods, e.g. tourniquets for suturing wounds; Holders or packages for needles or suture materials
    • A61B17/0401—Suture anchors, buttons or pledgets, i.e. means for attaching sutures to bone, cartilage or soft tissue; Instruments for applying or removing suture anchors
    • A61B2017/0446—Means for attaching and blocking the suture in the suture anchor
    • A61B2017/0458—Longitudinal through hole, e.g. suture blocked by a distal suture knot

Definitions

  • the present disclosure relates to surgical fixation devices in general and, more particularly, to fixation devices adapted for delivery of bone cement or other therapeutic agents to a repair site.
  • a suture anchor assembly including a delivery system which can deliver bone cement or other therapeutic agents into the central cannulation of the anchor that integrates with the surrounding bone architecture and thereby improves anchor fixation and/or facilitates healing. Holes in the anchor end of the shaft allow the bone cement or other therapeutic agent to pass through apertures in the anchor body into the region of the repair site.
  • the suture anchor assembly of this disclosure could be used alone or in combination with other therapeutic agents to be delivered to the repair site. Further examples of the suture anchor assembly of this disclosure may include one or more of the following, in any suitable combination.
  • the suture anchor assembly of this disclosure includes an anchor body having a proximal end, a distal end, and a cannulation extending along a longitudinal axis therebetween.
  • the cannulation is in communication with a region exterior to the anchor body through at least one aperture in a surface of the anchor body.
  • the assembly also includes an inserter having a handle and an elongated shaft. A distal end of the shaft is disposed within the cannulation of the anchor body.
  • a lumen extends through the shaft along the longitudinal axis and defines at least one opening, which may be a hole, at the distal end of the shaft.
  • the assembly further includes a delivery system attached to the handle.
  • the delivery system defines an internal volume in direct communication with the lumen of the shaft when the delivery system is attached to the handle. Actuation of the delivery system causes a therapeutic agent contained in the internal volume of the delivery system to be delivered through the lumen of the shaft into the region exterior to the anchor body through the at least one aperture in the surface of the anchor body.
  • the anchor body is in the form of an open helical coil.
  • the at least one aperture in the surface of the anchor body is defined by a space between turns of screw threads of the open helical coil.
  • the anchor body is made from a material selected to compliment the therapeutic agent.
  • a distal end of the anchor body has a suture bridge extending a partial length of the anchor body, and at least one rib extending from the suture bridge to the proximal end of the anchor body.
  • the anchor body is located on the shaft of the inserter such that a proximal end of the suture bridge is housed within a slot of the inserter and the at least one rib of the anchor body is housed within grooves of the inserter.
  • the delivery system is a manual injection syringe.
  • the therapeutic agent is one of bone cement, platelet rich plasma (PRP), anti -inflammatories, pain relievers, calcium phosphate-based bone graft substitute, autologous stem cells, collagen- based scaffold or other bioscaffold material, or combinations of the above.
  • the handle includes a grip and a connector coupled to the grip.
  • the connector includes a first channel in direct communication with a second channel of the grip.
  • a proximal end of the shaft extends extends through the first channel of the connector and the second channel of the grip.
  • the delivery system is attached to the handle by a delivery system interface, which may be a luer lock interface.
  • Examples of the method of delivering a therapeutic agent to a repair site of this disclosure include: using an inserter, inserting an anchor body as described above into a repair site; and actuating a delivery system attached to the handle of the inserter to deliver a therapeutic agent contained within the internal volume of the delivery system through at least one aperture in the surface of the anchor body into the repair site.
  • the delivery system is a manual injection syringe.
  • the therapeutic agent is bone cement and, after the bone cement has been delivered into the repair site, a mean pull-out strength of the anchor body is between about 389N and about 690N.
  • the therapeutic agent is selected from a group comprising platelet rich plasma (PRP), anti-inflammatories, pain relievers, calcium phosphate-based bone graft substitute, autologous stem cells, collagen- based scaffold or other bioscaffold material, or combinations thereof.
  • PRP platelet rich plasma
  • anti-inflammatories anti-inflammatories
  • pain relievers calcium phosphate-based bone graft substitute
  • autologous stem cells collagen- based scaffold or other bioscaffold material, or combinations thereof.
  • FIG. 1 is an exemplary suture anchor assembly of this disclosure
  • FIGS. 2 and 3 are examples of anchor bodies of the suture anchor assembly of FIG. 1;
  • FIG. 4 is a detail of the distal end of the shaft of the inserter of the suture anchor assembly of FIG. 1;
  • FIG. 5 is a detail of the distal end of the shaft of FIG. 4 inserted into the anchor body of FIG. 3;
  • FIG. 6 is a cross-sectional view of the handle assembly of the suture anchor assembly of FIG. 1;
  • FIGS. 7A-D illustrate an exemplary method of using the suture anchor assembly of
  • FIG. 1 DETAILED DESCRIPTION OF THE EMBODIMENTS
  • like components have been given the same reference numerals, regardless of whether they are shown in different examples.
  • the drawings may not necessarily be to scale and certain features may be shown in somewhat schematic form.
  • Features that are described and/or illustrated with respect to one example may be used in the same way or in a similar way in one or more other examples and/or in combination with or instead of the features of the other examples.
  • the suture anchor assembly 100 generally comprises an anchor body 102 distally located on an inserter 200, and a delivery system 300 attached to the proximal end of the inserter 200.
  • the delivery system 300 is configured to deliver bone cement 500 or other therapeutic agents through the anchor body 102 into a surrounding repair site, as further described below.
  • therapeutic agents may include platelet rich plasma (PRP), anti-inflammatories, pain relievers, calcium phosphate-based bone graft substitute, autologous stem cells, collagen-based scaffold or other bioscaffold material, or combinations of the above.
  • Examples of the delivery system 300 may include a manual linear syringe as shown in FIG. 1. However, other types of delivery systems, such as power syringes or screw style syringes, are also contemplated by this disclosure.
  • the inserter 200 generally includes a hollow shaft 201 fixedly attached to a handle assembly 210.
  • the handle assembly 210 can be made from plastic or other suitable non-metal and metal materials.
  • the shape and size of handle assembly 210 may be any shape and size necessary to facilitate insertion of the anchor body 102 into bone.
  • the shaft 201 is preferably made from a biocompatible metal material, such as stainless steel. However, other metal and non-metal materials that would withstand the forces applied during surgery are contemplated by this disclosure.
  • the length and diameter of the shaft 201 may also vary depending on the type of surgical repair.
  • FIG. 2 is a detailed illustration of an exemplary anchor body 102 of this disclosure.
  • the anchor body 102 includes a proximal end 101 and a distal end 107.
  • the distal end 107 also includes a suture bridge 105 that extends a partial length of the anchor body 102.
  • the suture bridge 105 includes a proximal end 105a and a distal end 105b.
  • the distal end 105b of the suture bridge 105 has a thickness greater than a thickness of the proximal end 105a of the suture bridge 105.
  • the distal end 105b of the suture bridge 105 has a concave shape.
  • a suture 110 or other flexible member can be housed within the anchor body 102 such that the suture 110 extends around the distal end 105b of the bridge 105 and the suture ends 112, 114 exit the proximal end 101 of the anchor body 102.
  • the anchor body 102 of FIG. 2 is an open helical coil anchor.
  • a majority of the anchor body 102 includes screw threads 103 in the form of an open helical coil, i.e. a connected series of continuous regularly spaced turns of screw threads 103 extending in a helical or spiral form substantially from the distal end 107 to the proximal end 101 of the anchor body 102.
  • Apertures 104 in the surface of the anchor body 102 are defined by the spaces in between the turns of the screw threads 103.
  • at least one longitudinally-extending rib 106 extends from the suture bridge 105 and along the interior of the screw threads 103, the purpose of which will be further described below. In the example of FIG. 2, there are two longitudinally extending ribs 106.
  • the screw threads 103 cover the proximal end 105a of the suture bridge 105.
  • FIG. 3 Another example of an anchor body 402 of this disclosure is shown in FIG. 3.
  • the screw threads 403 start at the proximal end 405a of the suture bridge 405 but do not cover the proximal end 405a of the suture bridge 405.
  • the anchor body 402 also includes webbing 408 between the most proximal screw thread 403a and the second most proximal screw thread 403b, as well between the most distal screw thread 403c and the second most distal screw thread 403d.
  • the webbing 408 gives the anchor body 402 torsion and compression strength.
  • Other non-limiting examples of open helical coil anchor bodies 102, 402 may be found in U.S. Publication No. 2013/0178901 to Smith & Nephew, Inc., incorporated by reference herein in its entirety.
  • the anchor body 102, 402 can be made from any combination of polymers, metal, bioabsorbable, or biocomposite material, which may be further selected to compliment the therapeutic agent 500.
  • the anchor body 102, 402 may be partially or entirely formed from a formulation of poly(lactic-co-glycolic) acid (PLGA), ⁇ -Tricalcium phosphate ( ⁇ -TCP) and calcium sulfate, poly-L-lactic acid - hydroxyapatite (PLLA-HA), poly-D-lactide (PDLA), polymers such as polyether ether ketone (PEEK), or variants thereof.
  • Biocomposite examples made from a combination of PLGA, ⁇ -TCP, and calcium sulfate are absorbable by the body, which is beneficial to natural healing.
  • An example formulation of PLGA, ⁇ -TCP, and calcium sulfate is described in U.S. Patent No. 8,545,866 to Smith & Nephew, Inc., incorporated by reference herein in its entirety.
  • Copolymers of polyglycolic acid (PGA) and polytrimethylene carbonate (TMC) are further examples of a bioabsorbable material.
  • Other commonly used materials that are capable of providing the strength needed to set the anchor body 102, 402 into bone and to hold the tissue graft in position while bone-to-tissue in-growth occurs are also contemplated by this disclosure.
  • the distal end of the shaft 201 of the inserter 200 includes a slot 202 with grooves 203 extending proximally from the slot 202 on each side of the shaft 201.
  • the shaft 201 also includes an internal cannulation 204 for passage of suture ends 112, 114 (FIG. 2).
  • One or more openings 205 may extend through a surface of the shaft 201 so as to be in communication with the internal cannulation 204.
  • the openings 205 and the open end of the cannulation 204 are configured for the passage of a bone cement 500 or other therapeutic agent, as further described below.
  • the openings 205 may be in the form of holes, perforations, meshes or other configurations depending upon the material to be used.
  • the anchor body (shown here for illustrative purposes as anchor body 402) is located on the shaft 201 of the inserter 200 such that the proximal end 405a of the suture bridge 405 is housed within the slot 202 of the inserter 200 and the ribs 406 of the anchor body 402 are housed within the grooves 203 of the inserter 200.
  • the openings 205 of the inserter 200 are aligned with the apertures 404 between the screw threads 403 of the anchor body 402 to allow the passage of a bone cement or other therapeutic agent into a repair site, as further described below.
  • the handle assembly 210 generally includes a grip 206 configured to be held by a user, and a connector 208 coupled to the grip 206.
  • the connector 208 has a first channel 212a in direct communication with a second channel 212b of the grip 206.
  • the proximal end of the grip 206 is configured to accept a delivery system interface 214, such as a luer lock syringe interface. As shown in FIG.
  • the proximal end of the shaft 201 is disposed within the first channel 212a and the second channel 212b such that the cannulation 204 of the shaft 201 is in direct communication with the internal volume 216 of the delivery system 300 when the delivery system 300 is attached to the inserter 200.
  • FIGS. 7A-D illustrate a method of using the suture anchor assembly, for example the suture anchor assembly 100 of FIG. 1.
  • the anchor body 102 may be driven into bone 600 using the inserter 200 of FIG. 1 with the delivery system 300 attached.
  • the anchor body 102 may be driven into bone 600 using a separate inserter (not shown) and the shaft 201 of the inserter 200 may be inserted into the anchor 102 after the separate inserter has been removed.
  • a separate inserter not shown
  • the bone cement 500 or other therapeutic agent contained in the delivery system 300 flows through the shaft 201 which is in direct communication with the delivery system 300 (FIG. 7B).
  • the shaft 201 is sealed by pressure so that it will not leak.
  • the delivery system 300 may then be removed from the shaft 201 and a device, such as an obturator 604, may optionally be inserted into the shaft 201 to urge the bone cement 500 or other therapeutic agent distally through the shaft 201 toward the repair site 602 (FIG. 7C).
  • the bone cement 500 or other therapeutic agent then exits through the distal end of the shaft 201 and through the fenestrated anchor body 402 into the surrounding repair site 602 (FIG. 7D).
  • the suture anchor assembly 100 of this disclosure advantageously allows the user to precisely place the bone cement 500 at the repair site 602 surrounding the anchor body 402.
  • augmentation technique demonstrates a 166% improvement in mean pullout strength, while prior studies to evaluate augmented anchors demonstrated a 46.9% improvement in mean pullout strength.
  • the method of this disclosure resulted in greater proportional increase in pullout strength secondary to interdigitation of cement with trabecular bone, and overall increased contact area at a hybrid bone-anchor-cement interface.
  • the suture anchor assembly 100 of FIG. 1 could also be used to aspirate fluid, such as bone marrow, into the delivery system 300.
  • the anchor body 102 could be delivered into bone, such as a humeral head, using the inserter 200.
  • the delivery system 300 could then be used in reverse to aspirate the bone marrow through the anchor body 102 and through the shaft 201 into the delivery system 300.
  • the aspirate could then be used whole or spun down to extract various elements, which could then be delivered by the suture anchor assembly 100 to repaired tissue, such as a tendon, to facilitate healing.

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  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Rheumatology (AREA)
  • Surgical Instruments (AREA)

Abstract

La présente invention concerne un ensemble d'ancrage de suture comprenant un système d'administration pour un agent thérapeutique, tel qu'un ciment osseux, qui est directement intégré dans un dispositif d'insertion d'ancrage. L'agent thérapeutique s'écoule à travers une tige du dispositif d'insertion dans une canulation centrale d'un corps d'ancrage fenêtré. Des trous situés dans l'extrémité d'ancrage de la tige permettent à l'agent thérapeutique de traverser les trous dans la tige et à travers les ouvertures dans le corps d'ancrage dans la région du site de réparation.
PCT/US2017/034712 2016-06-08 2017-05-26 Ensemble d'ancrage de suture pour l'administration d'un agent thérapeutique WO2017213893A1 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662347270P 2016-06-08 2016-06-08
US201662347289P 2016-06-08 2016-06-08
US62/347,289 2016-06-08
US62/347,270 2016-06-08
US201662384938P 2016-09-08 2016-09-08
US62/384,938 2016-09-08

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021183778A1 (fr) 2020-03-12 2021-09-16 Smith & Nephew, Inc. Implant de réparation tissulaire, compositions et procédé d'implantation
US20220079740A1 (en) * 2019-01-21 2022-03-17 Aju Pharm Co., Ltd. Orthopedic anchor and surgical tool integrated with anchor fastening member

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EP2582312A1 (fr) * 2010-06-15 2013-04-24 Rinaldo Giancola Dispositif de synthèse biologique sélective d'un tissu osseux
US20130178901A1 (en) 2010-03-10 2013-07-11 Tatsuya Arai Composite interference screws and drivers
US8545866B2 (en) 2004-10-29 2013-10-01 Smith & Nephew, Inc. Bioabsorbable polymers

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