WO2017209354A1 - Appareil et procédé d'attaque pour laser pulsé picoseconde médical - Google Patents

Appareil et procédé d'attaque pour laser pulsé picoseconde médical Download PDF

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Publication number
WO2017209354A1
WO2017209354A1 PCT/KR2016/011665 KR2016011665W WO2017209354A1 WO 2017209354 A1 WO2017209354 A1 WO 2017209354A1 KR 2016011665 W KR2016011665 W KR 2016011665W WO 2017209354 A1 WO2017209354 A1 WO 2017209354A1
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WO
WIPO (PCT)
Prior art keywords
laser
picosecond
nonlinear element
pulse
pulsed laser
Prior art date
Application number
PCT/KR2016/011665
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English (en)
Korean (ko)
Inventor
김정현
Original Assignee
원텍 주식회사
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Publication of WO2017209354A1 publication Critical patent/WO2017209354A1/fr

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    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
    • H01S3/10—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
    • H01S3/106—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating by controlling devices placed within the cavity
    • H01S3/108—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating by controlling devices placed within the cavity using non-linear optical devices, e.g. exhibiting Brillouin or Raman scattering
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
    • H01S3/10—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
    • H01S3/13—Stabilisation of laser output parameters, e.g. frequency or amplitude
    • H01S3/131—Stabilisation of laser output parameters, e.g. frequency or amplitude by controlling the active medium, e.g. by controlling the processes or apparatus for excitation
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S3/00—Lasers, i.e. devices using stimulated emission of electromagnetic radiation in the infrared, visible or ultraviolet wave range
    • H01S3/10—Controlling the intensity, frequency, phase, polarisation or direction of the emitted radiation, e.g. switching, gating, modulating or demodulating
    • H01S3/13—Stabilisation of laser output parameters, e.g. frequency or amplitude
    • H01S3/131—Stabilisation of laser output parameters, e.g. frequency or amplitude by controlling the active medium, e.g. by controlling the processes or apparatus for excitation
    • H01S3/1312—Stabilisation of laser output parameters, e.g. frequency or amplitude by controlling the active medium, e.g. by controlling the processes or apparatus for excitation by controlling the optical pumping
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01S—DEVICES USING THE PROCESS OF LIGHT AMPLIFICATION BY STIMULATED EMISSION OF RADIATION [LASER] TO AMPLIFY OR GENERATE LIGHT; DEVICES USING STIMULATED EMISSION OF ELECTROMAGNETIC RADIATION IN WAVE RANGES OTHER THAN OPTICAL
    • H01S2301/00—Functional characteristics
    • H01S2301/08—Generation of pulses with special temporal shape or frequency spectrum

Definitions

  • the present invention relates to a pulse control apparatus for a medical picosecond pulse laser generator, and to a high output pulse control apparatus for performing a high speed pulse switching speed at several pico (ps).
  • Picosecond pulsed lasers are being researched and applied in various fields such as IT, NT, BT, and ET. In the field of ultra-fine processing, it can be processed by minimizing heat affected zones, heat damage and cracks, and is processed by nonlinear optical phenomena of laser.
  • the present invention relates to the possibility of microtreatment without damaging surrounding tissues by high power picosecond pulsed laser in the field of medical treatment.
  • high-power picosecond pulsed lasers can deliver short pulses within the thermal relaxation time to tissues, indicating that pigment lesions caused by lasers require high power, as the absorption of pigments is relatively lower than the absorption of water.
  • the pigment particles can be effectively destroyed or disintegrated by the high-power picosecond pulse laser of the present invention, compared to the conventional nanosecond laser, and thus, the treatment effect is excellent in pigmented lesions such as tattoo removal or blemishes.
  • the high power picosecond pulsed laser refers to generating laser energy with extremely short pulse durations of several ps and high peak power per pulse.
  • the method of oscillating a laser in the form of a short pulse is classified into two methods. It is divided into Q-switching method and mode-locking method.
  • Q-switching method and mode-locking method.
  • Several methods have been developed to implement these approaches. There are an active amplitude or frequency electro-optic modulation method, a passive modulation method through a saturable absorber, a synchronous gain modulation method, and the like in the resonator. These methods are used for Q-switching and sometimes mode locking depending on the purpose required.
  • the Q-switching scheme is advantageous for obtaining high energy per pulse
  • the mode locking scheme is advantageous for obtaining short pulses. So the development history of picosecond laser pulses is consistent with the development of this mode locking method.
  • Active type is complicated overall system such as electronic circuit configuration to stabilize the output, and there is a difficulty in stable mode locking oscillation for a long time.
  • the passive type uses a saturated absorber, which makes it difficult to control the mode locking.
  • the mode locking technique is used mainly to realize the pulse of the picosecond region, but the output that can be generated by this technique is about several tens of mJ, and the minimum output of several hundred mJ is required for the pigment treatment in the medical field. need.
  • Picosecond pulse generation technology with hundreds of mJ output power requires at least 2-3 pulse generation techniques.
  • Manual control such as active control switching technology and inductive Brillouin Scattering (SBS), which combines cue switching and mode locking, or a combination of cue switching and cavity dumping or pulse slicing. Compression techniques can be used to generate high power picosecond pulses.
  • SBS inductive Brillouin Scattering
  • Patent Nos. 10-2015-0115349 and 10-2007-0133032 are known.
  • the technical problem to be solved by the present invention is input signal 101 for generating a laser from the outside; Resonator 106; First controller 102; A first driving device 105; A first nonlinear element 107; A high speed signal generator 104; Second controller 103; Second nonlinear element 109; It is to provide a medical picosecond pulse laser driving apparatus including a second driving device (110).
  • the high speed signal generator 104 generates a switching signal in real time with precision and provides synchronization.
  • the first nonlinear element 107 and the second nonlinear element 109 are positioned inside the resonator 106, and the first nonlinear element 107 and the second nonlinear element ( 109) to generate a high power picosecond pulsed laser.
  • a high speed signal generator 104 is provided in order to precisely control the first nonlinear element 107 and the second nonlinear element 109 by the first driving device 105 and the second driving device 110. It is characterized by.
  • the high speed signal generator 104 is implemented by hardware such as FPGA for real time high speed precision control.
  • the pigmented lesion solves the need for high power in that the absorption rate of the pigment is relatively lower than the absorption rate of water, and thus the present invention is compared with the conventional nanosecond laser.
  • Pigment particles can be destroyed or disintegrated efficiently by high-power picosecond pulsed laser, which is excellent in the treatment of pigmented lesions such as tattoo removal and blemishes.
  • FIG. 1 is a schematic diagram of a high power picosecond pulsed laser generation apparatus of the present invention.
  • FIG. 2 is a diagram illustrating a cue switch driving signal flow of the present invention.
  • FIG. 3 is a diagram of a picosecond pulsed laser signal implemented by the present invention.
  • the resonator 106 may include a first nonlinear element 107, a laser generating element 108, and a second nonlinear element ( 109).
  • a self-explanatory technique for generating a high power picosecond pulse laser in the resonator 106 is not described.
  • the laser generating device 108 When the laser generating device 108 is pumped by the pumping light source, the laser oscillates.
  • the oscillated laser locates the first nonlinear element 107 and the second nonlinear element 109 to generate an optical pulse having hundreds of picoseconds or subnanosecond pulses, and generates the laser externally.
  • the first controller 102 transmits a signal for generating the laser to the first drive device 105 to be transmitted by the first drive device 105 by the first non-linear element ( 107).
  • the laser oscillated by the driving of the first nonlinear element 107 generates a first laser Q switching optical pulse.
  • the signal transmitted from the first controller to generate the laser to the first driving device 105 is simultaneously transferred to the high speed signal generator 104.
  • the signal of the first controller transmitted to the high speed signal generator 104 is a second nonlinear element before the first laser Q switching optical pulse is generated by the optical switching action of the first nonlinear element 107 after a predetermined time elapses.
  • the high speed signal generator 104 transmits a signal for driving the second driving device to the second driving device 110 so that the second nonlinear element 109 is driven by the second driving device 110. ) Is driven.
  • the second Q switching is performed for a time equal to the picosecond pulse time to be extracted by the second nonlinear element 109.
  • an optical amplification is caused in the resonator, and after a predetermined time, the pulse is applied to the second nonlinear element again to generate a picosecond optical pulse.
  • the conventional Q switching method generates a pulse of several nanoseconds to several tens of nanoseconds with a high peak output after a certain time after the Q trigger signal (Laser Buildup Time) .
  • a Q switching trigger pulse was applied to the optical switching element (T1) and after a period of time ( ⁇ t1) a second time before the laser Q switching optical pulse appeared.
  • a time Q switching signal pulse is applied as much as the picosecond pulse time to be extracted to the optical switching device at the time T3 when the Q switching optical pulse is generated.
  • a time Q switching signal pulse is applied as much as the picosecond pulse time to be extracted to the optical switching device at the time T3 when the Q switching optical pulse is generated.
  • the resonator When the resonator generates optical amplification, and after a certain time ( ⁇ t3), another pulse is applied to the optical switching device to extract the picosecond optical pulse.
  • one or two optical switching elements of the resonator may be used and may be changed according to the Q switching sequence design.

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  • Physics & Mathematics (AREA)
  • Electromagnetism (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Optics & Photonics (AREA)
  • Nonlinear Science (AREA)
  • Lasers (AREA)
  • Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)

Abstract

La présente invention concerne un appareil de commande d'impulsions pour un appareil médical de génération d'impulsions picoseconde, l'appareil de commande d'impulsions de forte puissance permettant de commuter des impulsions de forte puissance à une grande vitesse correspondant à une plage de quelques picosecondes (ps). À cet effet, un premier élément non linéaire (107) et un second élément non linéaire (109) sont placés à l'intérieur d'un résonateur (106), et des lasers pulsés picoseconde de forte puissance sont générés au moyen du premier élément non linéaire (107) et du second élément non linéaire (109). Un appareil de génération de signal à grande vitesse séparé est utilisé de manière que le premier élément non linéaire (107) et le second élément non linéaire (109) soient commandés avec précision par un premier appareil d'attaque (105) et un second appareil d'attaque (110).
PCT/KR2016/011665 2016-06-03 2016-10-18 Appareil et procédé d'attaque pour laser pulsé picoseconde médical WO2017209354A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020160069521A KR20170137406A (ko) 2016-06-03 2016-06-03 의료용 피코초 펄스 레이저 구동 장치 및 방법
KR10-2016-0069521 2016-06-03

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Publication Number Publication Date
WO2017209354A1 true WO2017209354A1 (fr) 2017-12-07

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WO (1) WO2017209354A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102230744B1 (ko) * 2019-04-08 2021-03-22 원텍 주식회사 레이저 발생 장치

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100840057B1 (ko) * 2006-12-06 2008-06-19 미쓰비시덴키 가부시키가이샤 레이저 장치
KR20120003064A (ko) * 2010-07-02 2012-01-10 원테크놀로지 주식회사 세 개의 파장에서 롱펄스를 구현하는 레이저 공진기
JP2012216637A (ja) * 2011-03-31 2012-11-08 Hitachi Zosen Corp レーザ光の波長変換装置
KR101341744B1 (ko) * 2012-05-08 2013-12-16 홍정환 의료용 레이저 치료기의 전원장치
JP2016015440A (ja) * 2014-07-03 2016-01-28 キヤノン株式会社 被検体情報取得装置およびレーザー装置

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100840057B1 (ko) * 2006-12-06 2008-06-19 미쓰비시덴키 가부시키가이샤 레이저 장치
KR20120003064A (ko) * 2010-07-02 2012-01-10 원테크놀로지 주식회사 세 개의 파장에서 롱펄스를 구현하는 레이저 공진기
JP2012216637A (ja) * 2011-03-31 2012-11-08 Hitachi Zosen Corp レーザ光の波長変換装置
KR101341744B1 (ko) * 2012-05-08 2013-12-16 홍정환 의료용 레이저 치료기의 전원장치
JP2016015440A (ja) * 2014-07-03 2016-01-28 キヤノン株式会社 被検体情報取得装置およびレーザー装置

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