WO2017206083A1 - 一种动脉搏动信号测量设备及其压力传感器 - Google Patents

一种动脉搏动信号测量设备及其压力传感器 Download PDF

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Publication number
WO2017206083A1
WO2017206083A1 PCT/CN2016/084186 CN2016084186W WO2017206083A1 WO 2017206083 A1 WO2017206083 A1 WO 2017206083A1 CN 2016084186 W CN2016084186 W CN 2016084186W WO 2017206083 A1 WO2017206083 A1 WO 2017206083A1
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WIPO (PCT)
Prior art keywords
resistor
pressure sensor
substrate
voltage
signal
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Application number
PCT/CN2016/084186
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English (en)
French (fr)
Inventor
李灏
陈飞
Original Assignee
深圳纽迪瑞科技开发有限公司
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Application filed by 深圳纽迪瑞科技开发有限公司 filed Critical 深圳纽迪瑞科技开发有限公司
Priority to CN201680084189.4A priority Critical patent/CN108882879A/zh
Priority to PCT/CN2016/084186 priority patent/WO2017206083A1/zh
Priority to US16/305,555 priority patent/US20190313918A1/en
Publication of WO2017206083A1 publication Critical patent/WO2017206083A1/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A61B5/02141—Details of apparatus construction, e.g. pump units or housings therefor, cuff pressurising systems, arrangements of fluid conduits or circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02438—Detecting, measuring or recording pulse rate or heart rate with portable devices, e.g. worn by the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/0245—Detecting, measuring or recording pulse rate or heart rate by using sensing means generating electric signals, i.e. ECG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6832—Means for maintaining contact with the body using adhesives
    • A61B5/6833—Adhesive patches
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01L—MEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
    • G01L1/00—Measuring force or stress, in general
    • G01L1/20—Measuring force or stress, in general by measuring variations in ohmic resistance of solid materials or of electrically-conductive fluids; by making use of electrokinetic cells, i.e. liquid-containing cells wherein an electrical potential is produced or varied upon the application of stress
    • G01L1/22—Measuring force or stress, in general by measuring variations in ohmic resistance of solid materials or of electrically-conductive fluids; by making use of electrokinetic cells, i.e. liquid-containing cells wherein an electrical potential is produced or varied upon the application of stress using resistance strain gauges
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01L—MEASURING FORCE, STRESS, TORQUE, WORK, MECHANICAL POWER, MECHANICAL EFFICIENCY, OR FLUID PRESSURE
    • G01L9/00—Measuring steady of quasi-steady pressure of fluid or fluent solid material by electric or magnetic pressure-sensitive elements; Transmitting or indicating the displacement of mechanical pressure-sensitive elements, used to measure the steady or quasi-steady pressure of a fluid or fluent solid material, by electric or magnetic means
    • G01L9/02—Measuring steady of quasi-steady pressure of fluid or fluent solid material by electric or magnetic pressure-sensitive elements; Transmitting or indicating the displacement of mechanical pressure-sensitive elements, used to measure the steady or quasi-steady pressure of a fluid or fluent solid material, by electric or magnetic means by making use of variations in ohmic resistance, e.g. of potentiometers, electric circuits therefor, e.g. bridges, amplifiers or signal conditioning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0247—Pressure sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0261—Strain gauges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/04—Arrangements of multiple sensors of the same type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/1102—Ballistocardiography

Definitions

  • the present invention belongs to the field of medical devices, and in particular, to an arterial beating signal measuring device and a pressure sensor thereof.
  • An arterial pulsation signal refers to a pulse signal generated by a blood pulse generated by a blood pumping activity of a heart to cause a blood vessel to pump blood with the heart. This signal is directly related to physiological indicators such as heart rate, blood pressure, blood lipids, and hemodynamic changes.
  • Non-invasive measurement usually changes the blood flow by compressing the artery, and then measures the arterial beating signal according to the sound or vibration during the blood flow change. This type of method greatly reduces the suffering of patients with its inherent need for non-invasive surgery, and is widely used because of its low dependence on equipment and medical personnel.
  • the conventional non-invasive measuring device needs to be equipped with an additional pressing device (mostly pneumatic pressure) because the artery is pressed.
  • the wrist arm band leads to more components of the measuring device, is not easy to carry, has high cost, and has limited use environment.
  • An object of the present invention is to provide an arterial pulse signal measuring device and a pressure sensor thereof, which are intended to solve the problem that a conventional non-invasive arterial beating signal measuring device has many components and is difficult to be equipped with an additional pressing device. Carrying, high cost, and limited use environment.
  • the present invention is achieved by a pressure sensor of an arterial pulse signal measuring device connected to a measuring device in the arterial pulse signal measuring device, the pressure sensor including a substrate and being disposed on the substrate Pressure sensing detection circuit;
  • the pressure sensing detection circuit includes: a first resistor, a second resistor, a third resistor, and a fourth resistor, At least one of the first resistor, the second resistor, the third resistor, and the fourth resistor is a strain sensing resistor;
  • the first resistor, the third resistor, the second resistor, and the fourth resistor are electrically connected in sequence to form a full bridge circuit, and the common ends of the first resistor and the fourth resistor are a first voltage input end of the pressure sensor, a common end of the second resistor and the third resistor is a second voltage input end of the pressure sensor, and a common one of the first resistor and the third resistor The end is a voltage output end of the pressure sensor and is connected to the measuring device, and the common end of the second resistor and the fourth resistor is grounded;
  • the pressure sensor when the pressure sensor is adhered to the skin, the stratum corneum or other surface organ of the human or animal body through the substrate, and the first voltage input end and the second voltage input end of the pressure sensor are input constant Voltage ⁇ , the pressure sensor outputs a corresponding voltage signal to the measuring device according to an arterial pulse of the human body or the animal body, and the measuring device acquires a pulse signal of the human or animal body according to the voltage signal.
  • the present invention also provides an arterial beating signal measuring apparatus including a measuring device and the above-described pressure sensor.
  • the present invention employs an arterial beating signal measuring device including a pressure sensor and a measuring device, wherein the pressure sensor is attached to a skin, a stratum corneum or other superficial layer of a human or animal body, and the pressure sensor is a voltage input terminal and a second voltage input terminal input a constant voltage ⁇ , the pressure sensor outputs a corresponding voltage signal to the measuring device according to an arterial pulse of the human body or the animal body, and the measuring device acquires the human body or according to the voltage signal Animal arterial pulse signal.
  • the arterial beating signal measuring device provided by the invention has a simple structure, and can realize measurement of a beating signal of a human or animal body artery without an additional pressing device, which is cost-saving, convenient to carry, and is not restricted by the use environment. Brief description of the diagram
  • FIG. 1 is a schematic structural diagram of an arterial beating signal measuring apparatus according to an embodiment of the present invention.
  • FIG. 2 is a schematic cross-sectional view of a pressure sensor according to an embodiment of the present invention
  • 3 is a schematic circuit diagram of a pressure sensing detection circuit in a pressure sensor according to an embodiment of the present invention
  • 4(a) and 4(b) are schematic views showing the structure of the front side and the back side of the pressure sensor according to the embodiment of the present invention.
  • FIG. 5 is a schematic cross-sectional view of a pressure sensor according to another embodiment of the present invention.
  • FIG. 6 is a schematic view of a pressure sensor according to an embodiment of the present invention, which is adhered to a part to be detected by a double-sided adhesive;
  • FIG. 7 is a schematic diagram of a pressure sensor attached to a body to be inspected by a medical tape according to an embodiment of the present invention.
  • Embodiments of the present invention provide an arterial beating signal measuring device and a pressure sensor thereof.
  • FIG. 1 is a schematic structural diagram of an arterial beating signal measuring apparatus according to an embodiment of the present invention. For convenience of explanation, only parts related to the present invention are shown, which are described in detail as follows:
  • the arterial pulse signal measuring device includes a pressure sensor 1 and a measuring device 2.
  • the pressure sensor 1 is used to fit to the skin of the human or animal body, the stratum corneum or other parts with micro-deformation characteristics.
  • the measuring device 2 And outputting a corresponding voltage signal to the measuring device 2 according to the arterial pulse of the human or animal body, the measuring device
  • FIG. 2 is a cross-sectional view of a pressure sensor according to an embodiment of the present invention. For ease of explanation, only parts related to the present invention are shown, which are described in detail as follows:
  • the pressure sensor 1 includes a substrate 10 and a pressure sensing detection circuit disposed on the substrate 10, wherein the pressure sensing detection circuit is configured to detect a body or animal body arterial pulse signal, and the pressure sensing detection circuit
  • the method includes: a first resistor R1, a second resistor R2, a third resistor R3, and a fourth resistor R4.
  • At least one of the first resistor R1, the second resistor R2, the third resistor R3, and the fourth resistor R4 is a strain sensing resistor.
  • 3 is a circuit structural diagram of a pressure sensing detection circuit according to an embodiment of the present invention. As shown in FIG. 3, the first resistor R1, the third resistor R3, the second resistor R2, and the fourth resistor R4 are electrically connected in sequence.
  • the common end of the first resistor R1 and the fourth resistor R4 is the first voltage input terminal V+ of the pressure sensor 1
  • the common terminal of the second resistor R2 and the third resistor R3 is the second voltage input of the pressure sensor 1
  • the common terminal of the first resistor R 1 and the third resistor R3 is the voltage output terminal Vout of the pressure sensor 1
  • the common terminal of the third resistor R4 and the second resistor R2 is grounded.
  • the strain sensing resistor transmits the deformation ⁇ due to an external force
  • the resistance value thereof also changes correspondingly, so that when the first voltage input terminal and the second voltage input terminal of the pressure sensor 1 are applied With a constant voltage ⁇ , the voltage at the voltage output of the pressure sensor 1 changes as the resistance of the strain sensing resistor changes.
  • the pressure sensor 1 when the pressure sensor 1 is attached to the skin, the stratum corneum or other parts of the human or animal body having micro-deformation characteristics, and the first voltage input end and the second voltage input end of the pressure sensor 1 When the constant voltage ⁇ is input, the voltage output end of the pressure sensor 1 outputs a corresponding voltage signal to the measuring device 2 according to the arterial pulse of the human body, and the measuring device 2 analyzes and processes the voltage signal to obtain a human or animal body pulsation signal.
  • the pressure sensor 1 can transmit the voltage signal to the measuring device 2 by wire or wirelessly (FIG. 1 takes a wired transmission mode as an example), wherein the wireless transmission mode includes but is not limited to Bluetooth, WIFI, ZigBee and other transmission methods.
  • 4(a) and 4(b) are respectively a schematic structural view of a front side and a back side of a pressure sensor according to an embodiment of the present invention. For convenience of description, only parts related to the present invention are shown, which are described in detail below. :
  • the substrate 10 includes a front surface 10a and a back surface 10b, and both the front surface 10a and the back surface 10b can be used as the substrate 10 for skin, stratum corneum or other microscopy with human or animal body.
  • the side of the deformed feature that fits the side. It should be noted that the front side 10a and the back side 10b of the substrate 10 are not substantially different, just to illustrate that the two faces of the substrate are disposed facing away from each other.
  • one of the first resistor R1, the second resistor R2, the third resistor R2, and the fourth resistor R4 is disposed on the front surface 10a of the substrate, and the other three resistors are disposed on the substrate. Back 10b.
  • one of the first resistor R1, the second resistor R2, the third resistor R2, and the fourth resistor R4 is disposed on the back surface 10b of the substrate, and the other three resistors are disposed on the lining.
  • Two of the resistors 4 are disposed on the front surface 10a of the substrate, and the other two resistors are disposed on the back surface 10b of the substrate.
  • the first resistor R1, the second resistor R2, the third resistor R2, and the fourth resistor R are identical to the first resistor R1, the second resistor R2, the third resistor R2, and the fourth resistor R
  • the first resistor R1, the second resistor R2, the third resistor R2, and the fourth resistor R are identical to the first resistor R1, the second resistor R2, the third resistor R2, and the fourth resistor R
  • resistors are disposed on the front surface 10a of the substrate 10 and which resistors are disposed on the back surface 10b of the substrate 10 are determined according to actual conditions, and are not enumerated herein.
  • the resistors other than the strain sensing resistor are constant voltage resistors.
  • one of the first resistor R1, the second resistor R2, the third resistor R3, and the fourth resistor R4 is a strain sensing resistor, and the other three resistors are constant voltage resistors.
  • the first resistor R1, the second resistor R2, the third resistor R3, and the fourth resistor R are identical to the first resistor R1, the second resistor R2, the third resistor R3, and the fourth resistor R
  • the two resistors in 4 are strain sensing resistors, and the other two resistors are constant voltage resistors.
  • the first resistor R1, the second resistor R2, the third resistor R3, and the fourth resistor R are identical to the first resistor R1, the second resistor R2, the third resistor R3, and the fourth resistor R
  • the three resistors in 4 are strain sensing resistors, and the other resistor is a constant voltage resistor.
  • the first resistor R1, the second resistor R2, the third resistor R3, and the fourth resistor R are identical to the first resistor R1, the second resistor R2, the third resistor R3, and the fourth resistor R
  • the properties of the plurality of strain sensing resistors are the same.
  • the substrate 10 may employ a flexible circuit board.
  • the substrate 10 includes a first flexible circuit board 101 and a second flexible circuit board 102, and the first flexible circuit board 101 and the second flexible circuit board 102 are closely attached.
  • the substrate 10 is formed, and the non-bonding surface of the first flexible circuit board 101 and the non-bonding surface of the second flexible circuit board 102 are the front surface 10a and the back surface 10b of the substrate 10, respectively.
  • the thickness of the flexible circuit board is about 0.08 mm - 3 mm.
  • the substrate 10 is provided with a first voltage input port and a second voltage input respectively corresponding to the first voltage input end, the second voltage input end and the voltage output end of the pressure sensor 1.
  • Port and voltage output port, in the actual measurement, the pressure sensor 1 is attached to the human body or animal body to be measured a portion, and connecting the pressure sensor 1 to the measuring device 2 through a voltage output port on the substrate 10, and then inputting a voltage at the first voltage input port and the second voltage input port, thereby realizing a pulse signal to the human or animal body Measurement.
  • the pressure sensor 1 further includes a protective layer 50 that is attached to the outermost layer of the pressure sensor 1 to protect the pressure sensor 1.
  • the measuring device comprises a signal processing unit and a display unit.
  • a signal processing unit is configured to analyze and process the voltage signal to obtain a body or animal body beat signal, and obtain various physiological parameters of the human body or the animal according to the body or animal body beat signal (including It is not limited to heart rate, blood pressure, blood lipids, etc.; the display unit is connected to the processing unit, and is used to display the physiological parameters of the human or animal body.
  • the signal processing unit may specifically be a single chip microcomputer, an ARM processor or other programmable control device with data logic processing capability; the display unit may specifically be an LCD display, an LED display or other types of display screens.
  • the measuring device 2 includes, but is not limited to, a terminal that can implement signal analysis and result display, such as a computer, a mobile phone, an electronic watch, a home measuring instrument, and the like.
  • the pressure sensor 1 can be directly attached to the human body or the animal body to be measured by the double-sided tape 20.
  • the portion 30; the pressure sensor 1 may be attached to the medical tape 40 first, and the medical tape to which the pressure sensor 1 is attached may be attached 40 to the human or animal body to be measured portion 30.
  • the voltage output end of the pressure sensor 1 is first connected to the measuring device 2, and then the pressure sensor 1 is attached to the body or animal body to be measured, the human body or
  • the skin, stratum corneum or other superficial organs of the animal to be measured may be deformed with the pulsation of the artery.
  • the human body or the animal body is deformed.
  • the strain-sensing resistor in the pressure sensor 1 in which the skin, stratum corneum or other superficial organs are attached will have different degrees of deformation, resulting in a change in its resistance value, when the first voltage input and the second voltage input of the pressure sensor 1 With a constant input voltage ⁇ , the change of the resistance of the strain sensing resistor causes the output voltage of the voltage output of the pressure sensor 1 to change, and the measuring device 2 is pressed.
  • the voltage signal at the voltage output end of the force sensor 1 is analyzed and processed to obtain a human or animal body pulsation signal, and various human or animal body physiological parameters (including but not limited to heart rate, blood pressure, and the like) are obtained according to the human or animal body arterial pulse signal. Blood lipids, etc., the homogenous measuring device 2 displays various physiological parameters of the human body.
  • the pressure sensor 1 can be directly attached to the wrist artery of the human body, the fingernail or other skin, stratum corneum or other surface organs with obvious beat signals to measure the heart rate of the human body;
  • the pressure sensor 1 is integrated into a smart wearable device such as a sports bracelet, an electronic watch, a heart rate belt, etc., and is measured by combining the arterial pulse signal measured by the pressure sensor 1 with the human bioelectricity and photoelectric sensor data measured by the smart wearable device.
  • two sets of pressure sensors 1 can also be attached to the proximal limbs of the human body close to the heart, away from the distal end of the heart, by calculating the arterial pulse signals collected by the two sets of pressure sensors 1
  • the phase difference is used to measure the blood pressure of the human body, and the physiological characteristics such as arterial occlusion and arterial wall health are measured according to the delay of the phase difference; or the plurality of pressure sensors 1 are respectively attached to the abdominal cavity, the chest cavity, and the pelvic cavity of the human body.
  • the application scenarios of the arterial pulse signal measuring device include, but are not limited to, the above application scenarios.
  • Embodiments of the present invention employ an arterial beating signal measuring device including a pressure sensor and a measuring device, wherein the pressure sensor is attached to a skin, a stratum corneum or other surface organ of a human or animal body, and the pressure sensor The first voltage input terminal and the second voltage input terminal input a constant voltage ⁇ , and the pressure sensor outputs a corresponding voltage signal to the measuring device according to an arterial pulse of the human body or the animal body, and the measuring device acquires the voltage signal according to the voltage signal. Human or animal body arterial pulse signal.
  • the arterial beating signal measuring device provided by the embodiment of the invention has a simple structure, and can realize the measurement of the beating signal of the human body or the animal body without the need of an additional pressing device, which is cost-saving, convenient to carry, and is not restricted by the use environment. .

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Vascular Medicine (AREA)
  • General Physics & Mathematics (AREA)
  • Signal Processing (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

一种动脉搏动信号测量设备及其压力传感器，该动脉搏动信号测量设备包括压力传感器（1）和测量装置（2），当压力传感器（1）与人体或动物体的皮肤、角质层或其他表层器官相贴合，且压力传感器（1）的第一电压输入端（V+）和第二电压输入端（V-）输入恒定电压时，压力传感器（1）根据人体或动物体的动脉搏动输出相应的电压信号至测量装置（2），测量装置（2）根据所述电压信号获取人体或动物体动脉搏动信号。该动脉搏动信号测量设备结构简单，其不需要配备额外的加压设备便可实现对人体或动物体动脉搏动信号的测量，节约成本，携带方便，且不受使用环境限制。

Description

一种动脉搏动信号测量设备及其压力传感器 技术领域
[0001] 本发明属于医学设备领域， 尤其涉及一种动脉搏动信号测量设备及其压力传感 器。
背景技术
[0002] 动脉搏动信号是指由心脏泵血活动所产生的血液脉冲对血管壁的压力变化导致 动脉随心脏泵血而产生的搏动信号。 该信号与心率、 血压、 血脂以及血液动力 学变化等生理指标直接相关。
[0003] 目前动脉搏动信号的测量方法包括侵入测量法和非侵入测量法。 非侵入测量法 通常是通过压迫动脉使血流发生变化， 再根据血流变化过程中的声音或振动来 测量动脉搏动信号。 该类方法以其固有的无需幵创手术， 极大的减轻了患者的 痛苦， 同吋因其对设备和医务人员的专业性依赖不高等优点而被广泛采用。
[0004] 然而， 在采用传统的非侵入测量法对动脉搏动信号进行测量吋， 由于要对动脉 进行压迫， 因此传统的非侵入式测量设备都需要配备额外的加压装置 （多为充 气加压的腕臂带） ， 导致测量设备的构件较多， 不易携带， 成本较高， 且使用 环境受限。
技术问题
[0005] 本发明的目的在于提供一种动脉搏动信号测量设备及其压力传感器， 旨在解决 传统的非侵入式动脉搏动信号测量设备因需要配备额外的加压装置而导致其构 件较多， 不易携带， 成本较高， 且使用环境受限的问题。
问题的解决方案
技术解决方案
[0006] 本发明是这样实现的， 一种动脉搏动信号测量设备的压力传感器， 与所述动脉 搏动信号测量设备中的测量装置连接， 所述压力传感器包括衬底和设置于所述 衬底上的压力感应检测电路；
[0007] 所述压力感应检测电路包括： 第一电阻、 第二电阻、 第三电阻及第四电阻， 所 述第一电阻、 所述第二电阻、 所述第三电阻及所述第四电阻中至少有一个电阻 为应变感应电阻；
[0008] 所述第一电阻、 所述第三电阻、 所述第二电阻及所述第四电阻依次电连接并形 成全桥电路， 所述第一电阻与所述第四电阻的公共端为所述压力传感器的第一 电压输入端， 所述第二电阻与所述第三电阻的公共端为所述压力传感器的第二 电压输入端， 所述第一电阻与所述第三电阻的公共端为所述压力传感器的电压 输出端并连接所述测量装置， 所述第二电阻与所述第四电阻的公共端接地；
[0009] 当所述压力传感器通过所述衬底与人体或动物体的皮肤、 角质层或其他表层器 官相贴合， 且所述压力传感器的第一电压输入端和第二电压输入端输入恒定电 压吋， 所述压力传感器根据人体或动物体的动脉搏动输出相应的电压信号至所 述测量装置， 所述测量装置根据所述电压信号获取人体或动物体动脉搏动信号
[0010] 本发明还提供了一种动脉搏动信号测量设备， 所述动脉搏动信号测量设备包括 测量装置和上述的压力传感器。
发明的有益效果
有益效果
[0011] 本发明通过采用包括压力传感器和测量装置的动脉搏动信号测量设备， 当所述 压力传感器与人体或动物体的皮肤、 角质层或其他表层器官相贴合， 并且所述 压力传感器的第一电压输入端和第二电压输入端输入恒定电压吋， 所述压力传 感器根据人体或动物体的动脉搏动输出相应的电压信号至所述测量装置， 所述 测量装置根据所述电压信号获取人体或动物体动脉搏动信号。 本发明所提供的 动脉搏动信号测量设备结构简单， 其不需要配备额外的加压设备便可实现对人 体或动物体动脉搏动信号的测量， 节约成本， 携带方便， 且不受使用环境限制 对附图的简要说明
附图说明
[0012] 图 1是本发明实施例提供的动脉搏动信号测量设备的结构示意图；
[0013] 图 2是本发明实施例提供的压力传感器的横截面示意图； [0014] 图 3是本发明实施例提供的压力传感器中的压力感应检测电路的电路结构示意 图；
[0015] 图 4 (a) 和图 4 (b) 分别是本发明实施例提供的压力传感器的正面与背面的结 构示意图；
[0016] 图 5是本发明另一实施例提供的压力传感器的横截面示意图；
[0017] 图 6是本发明实施例提供的压力传感器通过双面胶与人体待检测部位进行贴合 的示意图；
[0018] 图 7是本发明实施例提供的压力传感器通过医用胶布与人体待检测部位进行贴 合的示意图。
本发明的实施方式
[0019] 为了使本发明的目的、 技术方案及优点更加清楚明白， 以下结合附图及实施例 ， 对本发明进行进一步详细说明。 应当理解， 此处所描述的具体实施例仅仅用 以解释本发明， 并不用于限定本发明。
[0020] 本发明实施例提供了一种动脉搏动信号测量设备及其压力传感器。
[0021] 图 1是本发明实施例提供的动脉搏动信号测量设备的结构示意图， 为了便于说 明， 仅示出了与本发明相关的部分， 详述如下：
[0022] 如图 1所示， 动脉搏动信号测量设备包括压力传感器 1和测量装置 2。 其中， 压 力传感器 1用于贴合至人体或动物体皮肤、 角质层或其他具有微形变特征的部位
， 并根据人体或动物体的动脉搏动输出相应的电压信号至测量装置 2， 测量装置
2用于根据所述电压信号获取人体或动物体动脉搏动信号。
[0023] 图 2是本发明实施例提供的压力传感器的横截面图， 为了便于说明， 仅示出了 与本发明相关的部分， 详述如下：
[0024] 如图 2所示， 压力传感器 1包括衬底 10和设置于衬底 10上的压力感应检测电路， 其中， 压力感应检测电路用于检测人体或动物体动脉搏动信号， 压力感应检测 电路包括： 第一电阻 Rl、 第二电阻 R2、 第三电阻 R3及第四电阻 R4。
[0025] 第一电阻 Rl、 第二电阻 R2、 第三电阻 R3及第四电阻 R4中至少有一个电阻为应 变感应电阻。 [0026] 图 3是本发明实施例提供的压力感应检测电路的电路结构图， 如图 3所示， 第一 电阻 Rl、 第三电阻 R3、 第二电阻 R2及第四电阻 R4依次电连接并形成全桥电路， 第一电阻 R1与第四电阻 R4的公共端为压力传感器 1的第一电压输入端 V+， 第二 电阻 R2与第三电阻 R3的公共端为压力传感器 1的第二电压输入端 V -， 第一电阻 R 1与第三电阻 R3的公共端为压力传感器 1的电压输出端 Vout， 第三电阻 R4与第二 电阻 R2的公共端接地。
[0027] 在本实施例中， 当应变感应电阻由于外力而发送形变吋， 其阻值也会发生相应 的变化， 这样， 当在压力传感器 1的第一电压输入端和第二电压输入端加以恒定 的电压吋， 压力传感器 1的电压输出端的电压会随应变感应电阻阻值的变化而发 生变化。
[0028] 在实际应用中， 当压力传感器 1与人体或动物体的皮肤、 角质层或其他具有微 形变特征的部位相贴合， 并且压力传感器 1的第一电压输入端和第二电压输入端 输入恒定电压吋， 压力传感器 1的电压输出端会根据人体的动脉搏动输出相应的 电压信号至测量装置 2， 测量装置 2对所述电压信号进行分析和处理， 得到人体 或动物体动脉搏动信号。
[0029] 在本发明实施例中， 压力传感器 1可将所述电压信号通过有线或无线的方式传 输至测量装置 2 (图 1以有线传输方式为例） ， 其中， 无线传输方式包括但不限 于蓝牙、 WIFI、 ZigBee等传输方式。
[0030] 图 4 (a) 和图 4 (b) 分别是本发明实施例提供的压力传感器的正面与背面的结 构示意图， 了便于说明， 仅示出了与本发明相关的部分， 详述如下：
[0031] 如图 2和图 4所示， 衬底 10包括正面 10a和背面 10b， 正面 10a和背面 10b均可以作 为衬底 10用于用于与人体或动物体皮肤、 角质层或其他具有微形变特征的部位 相贴合的一面。 需要说明的是， 衬底 10的正面 10a和背面 10b并没有本质上的区别 ， 只是为了说明衬底的两个面是背向设置的。
[0032] 作为本发明一实施例， 第一电阻 Rl、 第二电阻 R2、 第三电阻 R2及第四电阻 R4 中的一个电阻设置于衬底的正面 10a， 另外三个电阻设置于衬底的背面 10b。
[0033] 作为本发明另一实施例， 第一电阻 Rl、 第二电阻 R2、 第三电阻 R2及第四电阻 R 4中的一个电阻设置于衬底的背面 10b， 另外三个电阻设置于衬底的正面 10a。 [0034] 作为本发明另一实施例， 第一电阻 Rl、 第二电阻 R2、 第三电阻 R2及第四电阻 R
4中的两个电阻设置于衬底的正面 10a， 另外两个电阻设置于衬底的背面 10b。
[0035] 作为本发明另一实施例， 第一电阻 Rl、 第二电阻 R2、 第三电阻 R2及第四电阻 R
4均置于衬底的正面 10a。
[0036] 作为本发明另一实施例， 第一电阻 Rl、 第二电阻 R2、 第三电阻 R2及第四电阻 R
4均设置于衬底的背面 10b。
[0037] 在本发明实施例中， 具体哪些电阻设置于衬底 10的正面 10a， 哪些电阻设置于 衬底 10的背面 10b， 需根据实际情况来确定， 在此不一一列举。
[0038] 作为本发明一实施例， 第一电阻 Rl、 第二电阻 R2、 第三电阻 R3及第四电阻 R4 中， 除了应变感应电阻之外的其余电阻均为恒压电阻。
[0039] 作为本发明一实施例， 第一电阻 Rl、 第二电阻 R2、 第三电阻 R3及第四电阻 R4 中的一个电阻为应变感应电阻， 另外三个电阻为恒压电阻。
[0040] 作为本发明另一实施例， 第一电阻 Rl、 第二电阻 R2、 第三电阻 R3及第四电阻 R
4中的两个电阻为应变感应电阻， 另外两个电阻为恒压电阻。
[0041] 作为本发明另一实施例， 第一电阻 Rl、 第二电阻 R2、 第三电阻 R3及第四电阻 R
4中的三个电阻为应变感应电阻， 另外一个电阻为恒压电阻。
[0042] 作为本发明另一实施例， 第一电阻 Rl、 第二电阻 R2、 第三电阻 R3及第四电阻 R
4均为为应变感应电阻。
[0043] 在本发明实施例中， 当第一电阻 Rl、 第二电阻 R2、 第三电阻 R3及第四电阻 R4 中包括多个应变感应电阻吋， 多个应变感应电阻的属性均相同。
[0044] 作为本发明另一实施例， 衬底 10可以采用柔性电路板。
[0045] 作为本发明另一实施例， 如图 5所示， 衬底 10包括第一柔性电路板 101和第二柔 性电路板 102， 第一柔性电路板 101和第二柔性电路板 102紧密贴合形成衬底 10， 第一柔性电路板 101的非贴合面和第二柔性电路板 102的非贴合面分别为衬底 10 的正面 10a和背面 10b。 其中， 柔性电路板的厚度约为 0.08mm-3mm。
[0046] 作为本发明一实施例， 衬底 10上设置有分别与压力传感器 1的第一电压输入端 、 第二电压输入端及电压输出端相对应的第一电压输入端口、 第二电压输入端 口及电压输出端口， 在实际测量中， 将压力传感器 1贴合至人体或动物体待测量 部位， 并通过衬底 10上的电压输出端口将压力传感器 1连接至测量装置 2， 然后 在第一电压输入端口和第二电压输入端口加以输入电压， 即可实现对人体或动 物体动脉搏动信号的测量。
[0047] 作为本发明一实施例， 压力传感器 1还包括贴合于压力传感器 1的最外层， 对压 力传感器 1进行保护的保护层 50。
[0048] 作为本发明一实施例， 测量装置包括信号处理单元和显示单元。
[0049] 信号处理单元用于对所述电压信号进行分析和处理以得到人体或动物体动脉搏 动信号， 并根据所述人体或动物体动脉搏动信号获取各项人体或动物体生理参 数 （包括但不限于心率、 血压、 血脂等） ； 显示单元与所述处理单元连接， 且 用于将所述各项人体或动物体生理参数进行显示。 其中， 信号处理单元具体可 以是单片机、 ARM处理器或者其他具备数据逻辑处理能力的可编程控制器件； 显示单元具体可以是 LCD显示屏、 LED显示屏或者其他类型的显示屏。
[0050] 在本发明实施例中， 测量装置 2包括但不限于电脑、 手机、 电子表、 家用测量 仪等可实现信号分析及结果显示的终端。
[0051] 在实际应用中， 在对人体或动物体动脉搏动信号进行测量吋， 如图 6和图 7所示 ， 可通过双面胶 20直接将压力传感器 1贴合至人体或动物体待测量部位 30; 也可 先将压力传感器 1贴合至医用胶布 40上， 再将贴合有压力传感器 1的医用胶布贴 合 40至人体或动物体待测量部位 30。
[0052] 以下结合工作原理对上述实施例所提供的动脉搏动信号测量设备作进一步说明
[0053] 在对人体或动物体动脉搏动信号进行测量吋， 先将压力传感器 1的电压输出端 与测量装置 2进行连接， 再将压力传感器 1贴合于人体或动物体待测量部位， 人 体或动物体待测量部位的皮肤、 角质层或其他表层器官会随动脉的搏动而发生 形变， 当人体或动物体待测量部位的皮肤、 角质层或其他表层器官发生形变吋 ， 与人体或动物体的皮肤、 角质层或其他表层器官相贴合的压力传感器 1中的应 变感应电阻会产生不同程度的形变， 导致其阻值发生变化， 当在压力传感器 1的 第一电压输入端和第二电压输入端加以恒定的输入电压吋， 应变感应电阻阻值 的变化会导致压力传感器 1的电压输出端的输出电压发生变化， 测量装置 2对压 力传感器 1的电压输出端的电压信号进行分析和处理， 得到人体或动物体动脉搏 动信号， 并根据人体或动物体动脉搏动信号获取各项人体或动物体生理参数 （ 包括但不限于心率、 血压、 血脂等） ， 同吋测量装置 2将各项人体生理参数进行 显示。
[0054] 在实际应用中， 可以直接将压力传感器 1贴合至人体的腕部动脉、 指甲盖上或 其他动脉搏动信号明显的皮肤、 角质层或其他表层器官， 来测量人体的心率； 也可将压力传感器 1集成至运动手环、 电子表、 心率带等智能穿戴设备内， 通过 将压力传感器 1测量的动脉搏动信号与智能穿戴设备所测量的人体生物电、 光电 传感数据结合， 来测量人体的心率、 血压等生理变化特征； 还可以将两套压力 传感器 1分别贴合至人体的四肢靠近心脏的近端、 远离心脏的远端， 通过计算两 套压力传感器 1所采集的动脉搏动信号的相位差， 来测量人体的血压， 并根据相 位差的延吋情况来测量动脉堵塞情况、 动脉壁健康情况等生理特征； 或者将多 套压力传感器 1分别贴合至人体的腹腔、 胸腔、 盆腔等部位， 采集人体腔体的不 同部位随呼吸变化而产生的形变波形， 根据腔体不同部位形变波形的相位差及 信号变化速率， 来测量人体腔体的压力值。 需要说明的是， 本发明实施例所提 供的动脉搏动信号测量设备的应用场景包括但不限于以上应用场景。
[0055] 本发明实施例通过采用包括压力传感器和测量装置的动脉搏动信号测量设备， 当所述压力传感器与人体或动物体的皮肤、 角质层或其他表层器官相贴合， 并 且所述压力传感器的第一电压输入端和第二电压输入端输入恒定电压吋， 所述 压力传感器根据人体或动物体的动脉搏动输出相应的电压信号至所述测量装置 ， 所述测量装置根据所述电压信号获取人体或动物体动脉搏动信号。 本发明实 施例所提供的动脉搏动信号测量设备结构简单， 其不需要配备额外的加压设备 便可实现对人体或动物体动脉搏动信号的测量， 节约成本， 携带方便， 且不受 使用环境限制。
[0056] 以上所述仅为本发明的较佳实施例而已， 并不用以限制本发明， 凡在本发明的 精神和原则之内所作的任何修改、 等同替换和改进等， 均应包含在本发明的保 护范围之内。

Claims

权利要求书
[权利要求 1] 一种动脉搏动信号测量设备的压力传感器， 与所述动脉搏动信号测量 设备中的测量装置连接， 其特征在于， 所述压力传感器包括衬底和设 置于所述衬底上的压力感应检测电路；
所述压力感应检测电路包括： 第一电阻、 第二电阻、 第三电阻及第四 电阻， 所述第一电阻、 所述第二电阻、 所述第三电阻及所述第四电阻 中至少有一个电阻为应变感应电阻；
所述第一电阻、 所述第三电阻、 所述第二电阻及所述第四电阻依次电 连接并形成全桥电路， 所述第一电阻与所述第四电阻的公共端为所述 压力传感器的第一电压输入端， 所述第二电阻与所述第三电阻的公共 端为所述压力传感器的第二电压输入端， 所述第一电阻与所述第三电 阻的公共端为所述压力传感器的电压输出端并连接所述测量装置， 所 述第二电阻与所述第四电阻的公共端接地；
当所述压力传感器与人体或动物体的皮肤、 角质层或其他表层器官相 贴合， 且所述压力传感器的第一电压输入端和第二电压输入端输入恒 定电压吋， 所述压力传感器根据人体或动物体的动脉搏动输出相应的 电压信号至所述测量装置， 所述测量装置根据所述电压信号获取人体 或动物体动脉搏动信号。
[权利要求 2] 如权利要求 1所述的压力传感器， 其特征在于， 所述衬底包括正面和 背面， 所述正面和背面均可作为所述衬底用于与人体或动物体的皮肤 、 角质层或其他表层器官相贴合的一面。
[权利要求 3] 如权利要求 2所述的压力传感器， 其特征在于， 所述第一电阻、 所述 第二电阻、 所述第三电阻及所述第四电阻中的一个电阻设置于所述衬 底的正面， 另外三个电阻设置于所述衬底的背面。
[权利要求 4] 如权利要求 2所述的压力传感器， 其特征在于， 所述第一电阻、 所述 第二电阻、 所述第三电阻及所述第四电阻中的一个电阻设置于所述衬 底的背面面， 另外三个电阻设置于所述衬底的正面。
[权利要求 5] 如权利要求 2所述的压力传感器， 其特征在于， 所述第一电阻、 所述 第二电阻、 所述第三电阻及所述第四电阻中的两个电阻设置于所述衬 底的正面， 另外两个电阻设置于所述衬底的背面。
[权利要求 6] 如权利要求 2所述的压力传感器， 其特征在于， 所述第一电阻、 所述 第二电阻、 所述第三电阻及所述第四电阻均设置于所述衬底的正面。
[权利要求 7] 如权利要求 2所述的压力传感器， 其特征在于， 所述第一电阻、 所述 第二电阻、 所述第三电阻及所述第四电阻均设置于所述衬底的背面。
[权利要求 8] 如权利要求 1所述的压力传感器， 其特征在于， 所述衬底为柔性电路 板。
[权利要求 9] 如权利要求 1所述的压力传感器， 其特征在于， 所述衬底包括第一柔 性电路板和第二柔性电路板， 所述第一柔性电路板和所述第二柔性电 路板紧密贴合形成所述衬底， 所述第一柔性电路板的非贴合面和所述 第二柔性电路板的非贴合面分别为所述衬底的正面和背面。
[权利要求 10] 如权利要求 1所述的压力传感器， 其特征在于， 所述第一电阻、 所述 第二电阻、 所述第三电阻及所述第四电阻中， 除应变感应电阻之外的 其余电阻均为恒压电阻。
[权利要求 11] 一种动脉搏动信号测量设备， 包括测量装置， 其特征在于， 所述动脉 搏动信号测量设备还包括如权利要求 1-10任意一项所述的压力传感器
[权利要求 12] 如权利要求 11所述的动脉搏动信号测量设备， 其特征在于， 所述测量 装置包括信号处理单元和显示单元；
所述信号处理单元用于对所述电压信号进行分析和处理以得到人体或 动物体的动脉搏动信号， 并根据所述人体或动物体的动脉搏动信号获 取各项人体或动物体生理参数；
所述显示单元与所述处理单元连接， 且用于将所述各项人体或动物体 生理参数进行显示。
PCT/CN2016/084186 2016-05-31 2016-05-31 一种动脉搏动信号测量设备及其压力传感器 WO2017206083A1 (zh)

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