WO2017196271A1 - Pompe à sang à écoulement axial interne avec aimants passifs et palier radial hydrodynamique - Google Patents

Pompe à sang à écoulement axial interne avec aimants passifs et palier radial hydrodynamique Download PDF

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Publication number
WO2017196271A1
WO2017196271A1 PCT/TR2016/050144 TR2016050144W WO2017196271A1 WO 2017196271 A1 WO2017196271 A1 WO 2017196271A1 TR 2016050144 W TR2016050144 W TR 2016050144W WO 2017196271 A1 WO2017196271 A1 WO 2017196271A1
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WO
WIPO (PCT)
Prior art keywords
impeller
diffuser
pump
axial
axial flow
Prior art date
Application number
PCT/TR2016/050144
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English (en)
Inventor
Ismail LAZOGLU
Talha Irfan KHAN
Haris SHEHZAD
Original Assignee
Koc Universitesi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koc Universitesi filed Critical Koc Universitesi
Priority to PCT/TR2016/050144 priority Critical patent/WO2017196271A1/fr
Publication of WO2017196271A1 publication Critical patent/WO2017196271A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/205—Non-positive displacement blood pumps
    • A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
    • A61M60/237—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly axial components, e.g. axial flow pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/165—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart
    • A61M60/178—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable in, on, or around the heart drawing blood from a ventricle and returning the blood to the arterial system via a cannula external to the ventricle, e.g. left or right ventricular assist devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/403—Details relating to driving for non-positive displacement blood pumps
    • A61M60/422—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being electromagnetic, e.g. using canned motor pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/804—Impellers
    • A61M60/806—Vanes or blades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/81—Pump housings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/81—Pump housings
    • A61M60/812—Vanes or blades, e.g. static flow guides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/818—Bearings
    • A61M60/82—Magnetic bearings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/818—Bearings
    • A61M60/824—Hydrodynamic or fluid film bearings

Definitions

  • the present invention relates to an axial flow pump specially designed to supply blood to the body as a substitute or ventricular assist device of a heart.
  • Heart diseases are among the most common diseases and the number one cause of death globally.
  • the type of treatment for these diseases depends on their extent and severity. While some patients can be cured with rest and pharmaceutical therapy, there are those severe cases where the only option is heart surgery, including heart transplantation. Due to the shortage in the donor supplies, only about 5,000 heart transplantations can be performed each year in the world. Therefore, mechanical circulatory support systems have become prominent as the only solution for patients with end-stage heart failure and are used as bridge to transplant and even destination therapy.
  • a ventricular assist device is one such mechanical circulatory support system.
  • a VAD is a mechanical pump specially designed to supply blood to the body of a patient with end-stage heart failure.
  • Left Ventricular Assist Devices LVADs are the commonly used device for heart failure patients to support blood circulation and assist left ventricle function.
  • Current LVADs consist of two types in terms of mode of operation: pulsatile and rotary (continuous).
  • pulsatile pulsatile
  • rotary blood pumps are becoming more common because they are smaller in size, less costly to manufacture, less prone to mechanical damage and they require easier upkeep, resulting in improved quality of life for the patients.
  • Rotary pumps used in LVADs are further divided into two types: axial flow and centrifugal flow.
  • axial flow pumps the flow direction of the blood is parallel to the axis of rotation of the impeller in the pump.
  • Axial flow blood pumps conventionally comprise a cylindrical housing with an impeller as a rotor and optionally a flow straightener (minimizes pre-rotation of fluid entering the impeller and improves pump efficiency) and/or a diffuser (straightens the flow so that blood has a generally axial profile as it exits the pump and converts the dynamic pressure -velocity- of the fluid into desired static pressure to improve pump performance) encased inside.
  • the housing hosts the motor stator, such as a rotary magnetic flux generator, around the periphery of the rotor and the rotor contains permanent anisotropic magnets if a brushless DC motor is used.
  • the rotor is rotated by the magnetic co- relation between the two and an axial blood pump is obtained.
  • axial pumps are smaller in size compared to centrifugal pumps and they have smooth operations and a high flow rate.
  • problems associated with current axial flow devices include the following: (1) the clearance between blade tip and shroud causes slippage, thus affecting the performance of the pump, (2) low clearance is required to improve the performance, however, this causes shear in the blood which leads to hemolysis (the destruction of red blood cells), (3) low clearance also increases the possibility of collision between the high speed impeller and the stationary shroud, which can damage the pump, (4) possible dead water/wake areas, especially around the bearings, can lead to thrombosis (blood clotting), (5) the many pump design parameters are difficult to optimize in order to minimize blood damage, (6) the large thrust and torque loads or dried blood sticking to bearing surfaces can cause bearing seizures, (7) there are size, shape and weight limitations for implantation and patient comfort and mobility, (8) pumps with high power consumption require a large power supply, (9) percutaneous drive line between pump and power supply/controller and other support
  • U.S. Pat. No. 7,502,648 discloses an artificial cardiac pump having a housing in which a rotor is rotatably supported in a non-contact relation.
  • the invention comprises a housing, an impeller pivotally supported with respect to an axial body fixed in the housing and a brushless DC motor as the driving mechanism for rotating the impeller.
  • the impeller may comprise a shroud that houses the polar anisotropic permanent magnets or the magnets may be housed in the sleeve at the base of the impeller.
  • Motor stator is in the housing and comprises an electromagnetic coil. Permanent magnets are also utilized to stabilize the position of the impeller in the housing against the load caused by the pressure difference across the impeller.
  • hydrodynamic generation grooves are etched on the side surfaces of the impeller sleeve and the axial body around which it rotates.
  • U.S. Pat. No. 7,467,929 discloses an axial pump for the conveying of less stable multiple-phase fluids.
  • the pump comprises a pump casing that includes a motor stator and axial stabilizers around a tube-shaped hollow body which contains an impeller as a rotor, a flow straightener and a diffuser.
  • the rotor is magnetically borne via permanent magnets inserted in the axial ends of the impeller and corresponding magnets in the flow straightener and diffuser as well as the axial stabilizers mentioned above.
  • the impeller may contain a ring attached to one or both its axial ends, as well as a shroud-like ring fully covering the impeller blades. This ring provides further stability by way of hydrodynamic bearing to improve pump performance.
  • U.S. Pat. No. 6,742,999 to Berlin Heart AG discloses an axial blood pump with magnetic bearings.
  • the invention comprises a pump housing and a stabilizer housing around a tubular hollow body. Inside this hollow body are a flow straightener, a diffuser and an impeller as a rotor between the two.
  • the rotor is rotated by a brushless DC motor, with the electromagnetic coil stator placed in the pump housing and a passive magnet in the rotor hub.
  • the impeller is axially and radially stabilized by magnetic bearings by the permanent magnets in the flow straightener, diffuser and stabilizer housing. Hydrodynamic generation grooves are etched on the side surfaces of the impeller, flow straightener and diffuser to prevent wake areas from forming due to the magnetic bearing and increasing the efficiency of the pump.
  • U.S. Pat. No. 7,699,586 to Heartware, Inc. discloses a wide blade axial flow pump.
  • the pump comprises pump housing that hosts the motor stator and a wide blade impeller as the rotor.
  • the blades of the impeller get wider in the radial direction, ending with a wide external surface that can house permanent magnets to provide magnetic bearing as well as reduce slippage and provide hydraulic bearing and also increase pressure of the blood flow at the outlet.
  • Corresponding magnets of the same pole are placed in the pump housing.
  • the shape of the impeller eliminates the need for a flow straightener or diffuser allowing for a simpler mechanic design and reduced loss to vortexing.
  • the main disadvantage of this pump is that in includes complex blade geometry which has a high cost of manufacturing.
  • U.S. Pat. No. 5,527,159 to NASA discloses a rotary blood pump.
  • the invention comprises a flow straightener, an impeller and a diffuser attached by mechanical bearings, encased in a pump housing.
  • the housing hosts the motor stator which consists of electromagnetic coils.
  • the impeller is the rotor and the permanent magnets embedded in the impeller blades enable the rotational motion.
  • the impeller has two parts: in the upstream part, an inducer with variable pitch along its length is used to increase inlet head and prevent cavitation at the impeller; and in the downstream part is the impeller which is continuous to the inducer.
  • the invention produces fewer blood damage problems; however, mechanical contact bearing can be damaged in a short time span due to high rotational speed of impeller.
  • U.S. Pat. No. 8,366,599 to Thoratec Corporation discloses an implantable axial flow rotary blood pump.
  • the pump comprises an impeller adapted to be magnetically rotated within a housing by the interaction of magnets disposed on or in the impeller and stators disposed on or in the housing.
  • the impeller includes a plurality of blades encased in a support ring and hydrodynamic bearings that operate axially and radially.
  • the support ring of the impeller contains diagonal grooves along its length to use fluid leakage as lubricant.
  • the present invention aims to improve on the problems described in the prior art.
  • the invention makes use of magnetic bearings by permanent magnets and hydraulic bearings by the large area of the shroud around the impeller to stabilize the rotor.
  • the shroud also minimizes the chance of flow slippage and reduces hemolysis by decreasing the shear stress caused at the blade tips.
  • the object of the present invention is to provide an axial flow pump for the conveying of blood to be used as a ventricular assist device with improved performance and reduced blood damage.
  • Left ventricular assist devices are mechanical pumps designed to aid blood circulation in the body of a patient with congestive heart failure. Depending on the patient they can be used as bridge to recovery, bridge to transplant or destination therapy.
  • the invention relates to an axial flow rotary blood pump that can function as an implanted LVAD by attaching it to the left ventricle and aorta of a patient with end-stage heart failure.
  • the pump is designed to axially convey blood, driven by a brushless DC motor.
  • the impeller which functions as the rotor, has a rotating shroud and special blade design that increases pump efficiency and minimizes blood damage.
  • a flow straightener and diffuser serve to minimize flow losses and increase pump outlet pressure.
  • the pump makes use of magnetic and hydrodynamic bearings to overcome the disadvantage associated with fully mechanical and fully magnetic bearings.
  • Figure la is a longitudinal sectional view of an axial flow rotary pump in accordance with this invention.
  • Figure lb is a cross sectional view taken along line B-B of Figure la.
  • Figure lc is a cross sectional view taken along line C-C of Figure la.
  • Figure 2 is an exploded view of the axial flow rotary pump of Figure la.
  • Figure 3a is a perspective view of an impeller body.
  • Figure 3b is a longitudinal sectional view of the impeller body of Figure 3a.
  • Figure 3c is a cross sectional view taken along line A-A of Figure 3b.
  • Figure 4a is a perspective view of a flow straightener body.
  • Figure 4b is a front end view of the flow straightener body of Figure 4a.
  • Figure 4c is a cross sectional view taken along line A-A of Figure 4b.
  • Figure 5a is a perspective view of a diffuser body.
  • Figure 5b is a front end view of the diffuser body of Figure 5a.
  • Figure 5c is a cross sectional view taken along line A-A of Figure 5b. Referenced Parts List
  • FIGS la-2 show a preferred embodiment of an axial flow blood pump according to the invention.
  • the pump 10 comprises a tubular hollow pump casing 11 housing a motor stator 12 for preferably a brushless DC motor consisting of electromagnets which drive impeller 13 as a rotor, and also a flow straightener 14 and a diffuser 15. Blood is conveyed in the axial direction, from inlet 19 to outlet 20.
  • the impeller (13) is rotated by the electromagnetic interaction between permanent radial magnets 16 and the motor stator 12.
  • Permanent axial magnets 17 necessary for the magnetic bearing are arranged at the downstream end of flow straightener 14, upstream end of diffuser 15 and both ends of the impeller 13.
  • the permanent axial magnets (17) have the same pole facing each other, providing axial stabilization.
  • the blood flow slippage is directed backwards into hub gap 18, acting as hydrodynamic bearing and providing radial stabilization as well as eliminating the need for lubrication as blood is utilized to fulfill this function.
  • FIG. 3a-3c show an exemplary impeller (13) body.
  • the impeller 13 comprises a hub 131, impeller blades 132, rotatable shroud 133 and grooves 134.
  • the rotatable shroud 133 is attached to tips of impeller blades 132 and rotates along with the impeller (13). This arrangement allows minimizing shear stress generally formed at the blade tips that lead to blood damage.
  • the external part of rotatable shroud 133 is attached with permanent radial magnets 16.
  • the external body surface of the radial magnets 16 also forms part of the hydrodynamic bearing surface.
  • the impeller blades 132 form a screw thread configuration around impeller hub 131.
  • Impeller grooves (134) house permanent axial magnets 17 to provide axial stabilization.
  • FIG. 4a-4c show an exemplary flow straightener (14) body.
  • the flow straightener 14 comprises a flow straightener hub 141, flow straightener blades 142, flow straightener shroud 143 and flow straightener grooves 144.
  • Flow straightener (14) is attached to the pump casing 11 via shroud flow straightener 143.
  • the axially aligned straight flow straightener blades 142 are attached between flow straightener hub 141 and flow straightener shroud 143 and work to minimize flow losses.
  • the flow straightener grooves 144 house permanent axial magnets 17 to provide axial stabilization.
  • FIG. 5a-5c show an exemplary diffuser (15) body.
  • the diffuser 15 comprises a diffuser hub 151, diffuser blades 152, diffuser shroud 153 and diffuser grooves 154.
  • Diffuser (15) is attached to the pump casing 11 via diffuser shroud 153.
  • Diffuser blades 152 have specific inlet and exit angles.
  • Diffuser blades 152 are attached to variable area diffuser hub 151 and diffuser shroud 153. This variation in area produces a diverging path for blood to flow, thus increasing the outlet pressure of blood.
  • the diffuser grooves 154 house permanent axial magnets 17 to provide axial stabilization.
  • the present invention proposes a cardiac axial flow pump (10) effectuating conveying of blood in axial direction between an inlet (19) and an outlet (20), said cardiac axial flow pump (10) comprising a tubular hollow pump casing (11) housing a motor stator (12) driving an impeller (13) as a rotor rotated by electromagnetic interaction between a plurality of permanent radial magnets (16) and the motor stator (12), said cardiac axial flow pump (10) further comprising a flow straightener (14) and a diffuser (15).
  • said impeller (13) comprises an impeller hub (131) from which a plurality of impeller blades (132) extend to be integrally connected with a cylindrically-shaped rotatable shroud (133) in the manner that radially distant edges of said impeller blades (132) are fully covered by said rotatable shroud (133).
  • said plurality of permanent radial magnets (16) fully enclose outer surface of said rotatable shroud (133) in a fixedly attached relation thereto and to be rotatable along with the impeller (13).
  • said pump casing (11) and said permanent radial magnets (16) are disposed in the manner that the external body surface of the radial magnets (16) forms part of a hydrodynamic bearing surface in flow communication with a radial hub gap (18) created thereinbetween during operation of said cardiac axial flow pump (10).
  • said impeller blades (132) form a screw thread configuration around said impeller hub (131).
  • pitch of the screw thread configuration increases towards the outlet (20).
  • said flow straightener (14) comprises a flow straightener hub (141) from which a plurality of flow straightener blades (142) extends to be integrally connected with a cylindrically-shaped stationary flow straightener shroud (143) in the manner that radially distant edge of said at least one flow straightener blade (142) is fully covered by said flow straightener shroud (143).
  • said diffuser comprises a diffuser hub (151) from which a plurality of diffuser blades (152) extends to be integrally connected with a cylindrically-shaped stationary diffuser shroud
  • said impeller hub (131) comprises two opposite impeller grooves (134) proximate said flow straightener (14) and said diffuser (15), said impeller grooves (134) comprising permanent axial magnets (17) in an axially aligned positionment respectively relative to a flow straightener groove (144) and a diffuser groove
  • said flow straightener groove (144) and diffuser groove (154) respectively comprising permanent axial magnets (17), pairs of permanent axial magnets (17) respectively in a first impeller groove (134) and a corresponding flow straightener groove (144) and additionally in a second impeller groove (134) and a corresponding diffuser groove (154) having the same magnetic pole facing each other.
  • said diffuser hub (151) has a variable cross-sectional area perpendicular to the axial direction.
  • an electric motor in the form of a brushless DC motor with electromagnets within said motor stator (12) is provided.
  • said permanent axial magnets (17) in the flow straightener groove (144) and the diffuser groove (154) are respectively arranged at the downstream end of flow straightener (14) and upstream end of diffuser (15).

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Mechanical Engineering (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • External Artificial Organs (AREA)
  • Structures Of Non-Positive Displacement Pumps (AREA)

Abstract

La présente invention concerne une pompe à écoulement axial qui est adaptée pour pomper du sang qui peut être utilisée en tant que dispositif d'assistance ventriculaire gauche (LVAD). La présente invention concerne plus spécifiquement une pompe cardiaque à écoulement axial (10) effectuant le transport de sang dans une direction axiale entre une entrée (19) et une sortie (20), ladite pompe cardiaque à écoulement axial (10) comprenant un carter de pompe creux tubulaire (11) logeant un stator de moteur (12) entraînant un impulseur (13) sous la forme d'un rotor mis en rotation par interaction électromagnétique entre une pluralité d'aimants permanents radiaux (16) et le stator de moteur (12), ladite pompe cardiaque à écoulement axial (10) comprenant en outre un redresseur d'écoulement (14) et un diffuseur (15). Les pales d'impulseur sont fixées à et totalement recouvertes par un carénage rotatif qui est fixé avec des aimants radiaux qui constituent un palier hydrodynamique.
PCT/TR2016/050144 2016-05-13 2016-05-13 Pompe à sang à écoulement axial interne avec aimants passifs et palier radial hydrodynamique WO2017196271A1 (fr)

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Application Number Priority Date Filing Date Title
PCT/TR2016/050144 WO2017196271A1 (fr) 2016-05-13 2016-05-13 Pompe à sang à écoulement axial interne avec aimants passifs et palier radial hydrodynamique

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10722631B2 (en) 2018-02-01 2020-07-28 Shifamed Holdings, Llc Intravascular blood pumps and methods of use and manufacture
CN112316297A (zh) * 2020-11-03 2021-02-05 四川大学华西医院 一种中空心脏辅助泵
CN113368388A (zh) * 2021-06-21 2021-09-10 内蒙古工业大学 一种左心室辅助搏动式血泵
US11185677B2 (en) 2017-06-07 2021-11-30 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
US11511103B2 (en) 2017-11-13 2022-11-29 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
US11654275B2 (en) 2019-07-22 2023-05-23 Shifamed Holdings, Llc Intravascular blood pumps with struts and methods of use and manufacture
US11724089B2 (en) 2019-09-25 2023-08-15 Shifamed Holdings, Llc Intravascular blood pump systems and methods of use and control thereof
US11964145B2 (en) 2019-07-12 2024-04-23 Shifamed Holdings, Llc Intravascular blood pumps and methods of manufacture and use

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5211546A (en) * 1990-05-29 1993-05-18 Nu-Tech Industries, Inc. Axial flow blood pump with hydrodynamically suspended rotor
US5527159A (en) 1993-11-10 1996-06-18 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Rotary blood pump
US6742999B1 (en) 1999-04-20 2004-06-01 Berlin Heart Ag Device for delivering single-phase or multiphase fluids without altering the properties thereof
WO2007003351A1 (fr) * 2005-07-01 2007-01-11 Coras Medical Pompe axiale a pale en forme de spirale
US7467929B2 (en) 2001-02-16 2008-12-23 Berlin Heart Gmbh Device for axially conveying fluids
US7502648B2 (en) 2003-04-30 2009-03-10 Mitsubishi Heavy Industries, Ltd. Artificial cardiac pump
US7699586B2 (en) 2004-12-03 2010-04-20 Heartware, Inc. Wide blade, axial flow pump
WO2012112129A1 (fr) * 2011-02-15 2012-08-23 Toptop Koral Pompe cardiaque à flux axial
US8366599B2 (en) 2003-10-09 2013-02-05 Thoratec Corporation Axial flow blood pump

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5211546A (en) * 1990-05-29 1993-05-18 Nu-Tech Industries, Inc. Axial flow blood pump with hydrodynamically suspended rotor
US5527159A (en) 1993-11-10 1996-06-18 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Rotary blood pump
US6742999B1 (en) 1999-04-20 2004-06-01 Berlin Heart Ag Device for delivering single-phase or multiphase fluids without altering the properties thereof
US7467929B2 (en) 2001-02-16 2008-12-23 Berlin Heart Gmbh Device for axially conveying fluids
US7502648B2 (en) 2003-04-30 2009-03-10 Mitsubishi Heavy Industries, Ltd. Artificial cardiac pump
US8366599B2 (en) 2003-10-09 2013-02-05 Thoratec Corporation Axial flow blood pump
US7699586B2 (en) 2004-12-03 2010-04-20 Heartware, Inc. Wide blade, axial flow pump
WO2007003351A1 (fr) * 2005-07-01 2007-01-11 Coras Medical Pompe axiale a pale en forme de spirale
WO2012112129A1 (fr) * 2011-02-15 2012-08-23 Toptop Koral Pompe cardiaque à flux axial

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11185677B2 (en) 2017-06-07 2021-11-30 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
US11717670B2 (en) 2017-06-07 2023-08-08 Shifamed Holdings, LLP Intravascular fluid movement devices, systems, and methods of use
US11511103B2 (en) 2017-11-13 2022-11-29 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
US10722631B2 (en) 2018-02-01 2020-07-28 Shifamed Holdings, Llc Intravascular blood pumps and methods of use and manufacture
US11229784B2 (en) 2018-02-01 2022-01-25 Shifamed Holdings, Llc Intravascular blood pumps and methods of use and manufacture
US11964145B2 (en) 2019-07-12 2024-04-23 Shifamed Holdings, Llc Intravascular blood pumps and methods of manufacture and use
US11654275B2 (en) 2019-07-22 2023-05-23 Shifamed Holdings, Llc Intravascular blood pumps with struts and methods of use and manufacture
US11724089B2 (en) 2019-09-25 2023-08-15 Shifamed Holdings, Llc Intravascular blood pump systems and methods of use and control thereof
CN112316297A (zh) * 2020-11-03 2021-02-05 四川大学华西医院 一种中空心脏辅助泵
CN113368388A (zh) * 2021-06-21 2021-09-10 内蒙古工业大学 一种左心室辅助搏动式血泵
CN113368388B (zh) * 2021-06-21 2022-12-02 内蒙古工业大学 一种左心室辅助搏动式血泵

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