WO2017174139A1 - Syringe calibration instrument - Google Patents

Syringe calibration instrument Download PDF

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Publication number
WO2017174139A1
WO2017174139A1 PCT/EP2016/057636 EP2016057636W WO2017174139A1 WO 2017174139 A1 WO2017174139 A1 WO 2017174139A1 EP 2016057636 W EP2016057636 W EP 2016057636W WO 2017174139 A1 WO2017174139 A1 WO 2017174139A1
Authority
WO
WIPO (PCT)
Prior art keywords
syringe
calibration instrument
recess
barrel
plunger
Prior art date
Application number
PCT/EP2016/057636
Other languages
French (fr)
Inventor
Karsten Roth
Dirk Kreder
Original Assignee
Cinfa Biotech S.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cinfa Biotech S.L. filed Critical Cinfa Biotech S.L.
Priority to PCT/EP2016/057636 priority Critical patent/WO2017174139A1/en
Priority to ES201630495U priority patent/ES1168461Y/en
Publication of WO2017174139A1 publication Critical patent/WO2017174139A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31536—Blocking means to immobilize a selected dose, e.g. to administer equal doses
    • A61M2005/3154—Blocking means to immobilize a selected dose, e.g. to administer equal doses limiting maximum permissible dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means

Abstract

The invention relates to a syringe calibration instrument (10), a kit comprising such syringe calibration instrument (10) and a method for calibrating a syringe. The syringe calibration instrument (10) comprises a first recess (11) configured to receive a barrel (21) of a syringe (20), a second recess (12) configured to receive a finger flange (22) of the syringe (20), a movement portion (13) configured to allow a movement of a plunger (23) of the syringe (20) relative to the barrel (21), and a stopper portion (14) configured to stop the movement of the plunger (23) relative to the barrel (21). The first recess (11) and the second recess (12) extend perpendicular to each other to fixedly hold the syringe (20) in a direction along the barrel (21). The stopper portion (14) is arranged with a predetermined distance relative to the second recess (12) to allow only a limited travel of the plunger (23) in the barrel (21) to retain a predetermined volume in the syringe (20).

Description

SYRINGE CALIBRATION INSTRUMENT
FIELD OF THE INVENTION
The invention relates to a syringe calibration instrument, a kit comprising such syringe calibration instrument and a method for calibrating a syringe. The syringe calibration instrument allows only a limited travel of a syringe to retain a predetermined volume of the content in the syringe.
BACKGROUND OF THE INVENTION
There are some possibilities known to retain a predetermined volume of content in the syringe, as for example a refilling into another syringe or a use of spacers causing a plunger rod to stop at a certain distance from an end position. However, these possibilities lack the desired usability and accuracy.
SUMMARY OF THE INVENTION
Hence, there may be a need to provide a syringe calibration instrument which improves a handling of syringes in view of a predetermined volume of content in the syringe.
This need is solved by the subject-matters of the independent claims, wherein further embodiments are incorporated in the dependent claims.
According to the present invention, a syringe calibration instrument is presented. The syringe calibration instrument comprises:
· a first recess configured to receive a barrel of a syringe,
• a second recess configured to receive a finger flange of the syringe,
• a movement portion configured to allow a movement between a plunger of the syringe and the barrel, and
• a stopper portion configured to stop the movement between the plunger and the barrel.
The first recess and the second recess extend perpendicular to each other to hold the syringe in a defined direction along the barrel. The stopper portion of the syringe calibration instrument is arranged with a predetermined distance relative to the second recess to allow only a limited travel of the plunger in the barrel to retain a predetermined volume in the syringe. In other words, the first recess may hold the barrel of the syringe and the second recess may hold and precisely position the finger flange or wings of the syringe. The two recesses may extend perpendicular to each other to fixedly hold the syringe in a direction along the barrel. Thereby, the syringe can be inserted into the syringe calibration instrument in only one, clearly defined orientation and direction. Both recesses may be cavities with at least two contact points or surfaces to hold the barrel or the finger flange, respectively.
The movement portion may enable a movement between the plunger and the barrel of the syringe to allow an output of a content or agent comprised in the barrel. The syringe calibration instrument may be longer than the barrel and thereby offer the stopper portion to mechanically stop the movement of the plunger relative to the barrel after a predetermined length of the movement and thereby before a predetermined volume of content or agent is ejected from the syringe. The predetermined length of the movement may be defined to keep the predetermined volume of content within the syringe and to eject the rest.
In other words, the fixed distance between the second recess and the stopper portion may define the predetermined length of the movement of the barrel to keep a predetermined volume within the syringe. The stopper portion may stop the plunger in a position or at a stopping point that pre-empties the syringe, but keeps the predetermined volume of content in the syringe. Thereby, the handling of syringes in view of a
predetermined volume of content in the syringe is greatly improved. In particular, a safe handling of prefilled syringes and retention of a predetermined volume of content in the syringe is improved. Further, usability is improved in view of ejecting a certain volume from a syringe with e.g. a staked needle which poses a needle-stick injury risk as this risk is mitigated by the use of the syringe calibration instrument.
Exemplarily, a 1.0 ml syringe pre-loaded with e.g. 0.6 ml of a pharmaceutical agent can be emptied to an exact level of e.g. 0.3 ml +/- 5 %. Then, only and exactly these 0.3 ml of the pharmaceutical agent remaining in the syringe can be injected into e.g. a patient or a volunteer of e.g. a phase I study for comparing the effectiveness of a biosimilar agent to an existing product. The tolerance level may be +/- 0.0075 ml. However, the syringe calibration instrument can be dimensioned and adapted for all kind of syringe sizes and different predetermined volumes of content to remain in the syringe. The syringe calibration instrument may also be dimensioned and adapted for all kind of syringe types and materials.
The syringe may be any device configured for a sub-cutaneous or intravenous, or intramuscular delivery of a medium or agent. The content in the barrel of the syringe may be any kind of agent, drug, solution, medium or the like. In an example, the first recess and the second recess are dimensioned to allow a release of the syringe by pushing the syringe from the syringe calibration instrument through a recess. Exemplarily, the first recess and the second recess may also be dimensioned to allow a release of the syringe by turning the syringe calibration instrument upside down. In an example, a rear side of the syringe calibration instrument is essentially a flat contact surface configured to rest on a work surface. The syringe calibration instrument may have a conical shape towards a front shape of the syringe. In an example, a front side of the syringe calibration instrument is configured to be essentially flush with the syringe. This means a top surface of the syringe calibration instrument may be at one level with a highest point of the syringe barrel.
The syringe calibration instrument may have soft radiuses to be comfortably and safely handled by the user. In an example, the syringe calibration instrument further comprises two essentially semicircular gripping holes arranged along the first recess. Further, the syringe calibration instrument may have at least roughened surface portions to be easily gripped by a user wearing gloves.
In an example, the stopper portion comprises a stopper passage with a cross section, wherein the cross section of the stopper passage is compatible to a cross section of a rod of the plunger to allow a movement of the rod relative to the barrel. Further, the cross section of the stopper passage may be incompatible to a cross section of an end disc or head of the plunger to stop a movement of the head relative to the barrel. Exemplarily, the cross section of the rod of the plunger may be cross-shaped, while the cross section of the head of the plunger may be round or circular. The head of the plunger may also be used as additional alignment surface.
In an example, the cross section of the stopper passage is provided with a diameter, wherein the diameter of the stopper passage matches to a diameter of the rod to allow the movement of the rod relative to the barrel. Further, the diameter of the stopper passage may be smaller than a diameter of the head of the plunger to stop the movement of the head relative to the barrel.
In an example, the first recess and the second recess are dimensioned to receive a barrel with about 8 mm outer diameter and about 1.0 ml volume, wherein the predetermined distance between the second recess and the stopper portion is dimensioned to keep a predetermined volume of 0.3 ml in the syringe. In this example, the predetermined distance between the second recess and the stopper portion amounts to about 15 mm and preferably to 14.35 mm. The predetermined distance between the second recess and the stopper portion may also be dimensioned to keep a predetermined volume of 0.45 ml in the syringe. The predetermined distance between the second recess and the stopper portion then amounts to about 7 mm and preferably to 7.18 mm.
In an example, a spring member is arranged in the second recess, wherein the spring member is configured for an interaction with the finger flange. The spring member may be a unitary part of the syringe calibration instrument. The spring member may also be an accessory. It may be formed as a spring disc or a coiled spring or at least two spring arms. The spring member may be arranged within the second recess to push the finger flange towards a wall of the second recess to fixedly hold the syringe relative to the syringe calibration instrument.
In an example, the syringe calibration instrument further comprises an adjustment element attached to the stopper portion and configured to adjust the syringe calibration instrument to different syringes and/or different predetermined volumes. The adjustment element may be at least a shim, spacer unit or filler plate to adjust the distance between the second recess and the stopper portion defining the predetermined length of the movement of the barrel to keep the predetermined volume within the syringe. The adjustment element could also be a rotating mechanism adjusting the distance to predetermined end points.
The syringe calibration instrument may also be dimensioned to receive a syringe with a barrel with about 6.35 mm inner diameter, with an upper tolerance of 6.45 mm and a lower tolerance of 6.25mm, wherein the predetermined distance between the second recess and the stopper portion (= distance "2r_s") is flexibly dimensioned to keep a range of predetermined volumes in the syringe. The distance 2r_s can for example be determined by the use of spacer units with a certain height modifying the distance 2r_s, wherein for each 1/100 of a milliliter a spacer with a dimension of for example 0.4783 mm is used. In an example, a spacer with a dimension to adjust the distance 2r_s to 4.783 mm is used resulting in a retained volume in the syringe of for example 0.1 ml.
The syringe calibration instrument may be made of a plastic material or a compound material. The plastic material may be a thermoplastic material with preferably good rigidity and good thermal mechanical strength. The plastic material may be translucent and/or colored. The plastic material may be a polyetherimide or PEEK or any other polymer. In an example, the syringe calibration instrument is made of TECAPEI. According to the present invention, also a kit comprising such syringe calibration instrument is presented. The syringe calibration instrument comprises:
• a first recess configured to receive a barrel of a syringe,
· a second recess configured to receive a finger flange of the syringe,
• a movement portion configured to allow a movement between a plunger of the syringe and the barrel, and
• a stopper portion configured to stop the movement between the plunger and the barrel.
The first recess and the second recess extend perpendicular to each other to fixedly hold the syringe in a direction along the barrel. The stopper portion is arranged with a predetermined distance relative to the second recess to allow only a limited travel of the plunger in the barrel to keep a predetermined volume in the syringe.
The predetermined or fixed distance between the second recess and the stopper portion may define a predetermined length of a movement of the barrel to keep a
predetermined volume within the syringe. The stopper portion may stop the plunger at a stopping point that pre-empties the syringe and keeps the predetermined volume of content in the syringe.
According to the present invention, also a method for calibrating a syringe is presented. The method comprises the following steps:
- inserting a syringe in a syringe calibration instrument as described above,
- moving a plunger of the syringe relative to a barrel of the syringe until a stopper portion of the syringe calibration instrument stops the movement of the plunger relative to the barrel to retain a predetermined volume in the syringe, and
- removing the syringe from the syringe calibration instrument to obtain a calibrated syringe.
It shall be understood that the syringe calibration instrument and the kit comprising such syringe calibration instrument according to the independent claims have similar and/or identical preferred embodiments, in particular, as defined in the dependent claims. It shall be understood further that a preferred embodiment of the invention can also be any combination of the dependent claims with the respective independent claim.
These and other aspects of the present invention will become apparent from and be elucidated with reference to the embodiments described hereinafter. BRIEF DESCRIPTION OF THE DRAWINGS
Exemplary embodiments of the invention will be described in the following with reference to the accompanying drawings:
Fig. 1 shows a schematic 3D drawing of an example of a kit comprising a syringe calibration instrument according to the invention.
Fig. 2 shows schematically and exemplarily different views of the kit comprising a syringe calibration instrument according to the invention.
Fig. 3 shows schematically and exemplarily a detail of one of the views shown in Fig. 2.
DETAILED DESCRIPTION OF EMBODIMENTS
Fig. 1 shows schematically and exemplarily a 3D drawing of a kit comprising a syringe calibration instrument 10 according to the invention. The syringe calibration instrument 10 comprises:
• a first recess 11 holding a barrel 21 of a syringe 20,
• a second recess 12 holding a finger flange 2 of the syringe 20,
• a movement portion 13 allowing a movement between a plunger 23 of the syringe 20 and the barrel 21, and
· a stopper portion 14 stopping the movement between the plunger 23 and the barrel 21.
The first recess 11 and the second recess 12 extend perpendicular to each other to fixedly hold the syringe 20 in a direction along the barrel 21. The stopper portion 14 is arranged with a predetermined distance relative to the second recess 12 to allow only a limited travel of the plunger 23 in the barrel 21 to keep a predetermined volume in the syringe 20. The plunger 23 with its head 232 is shown in an initial position A and in a blocked position B.
Different views of such kit comprising a syringe calibration instrument 10 are shown in Fig. 2. The first recess 11 holds the barrel 21 of the syringe 20 and the second recess 12 holds and precisely positions the finger flange 2 of the syringe 20. The movement allowed between the plunger 23 and the barrel 21 of the syringe 20 outputs an agent comprised in the barrel 21. The plunger 23 with its head 232 is shown in an initial position A and in a blocked position B. The movement is stopped after a predetermined length and thereby before a predetermined volume of the agent is ejected from the syringe 20. In other words, the fixed distance between the second recess 12 and the stopper portion 14 defines the predetermined length of the movement of the barrel 21 to keep a predetermined volume within the syringe 20.
Here, the shown syringe 20 is a 1.0 ml syringe pre-loaded with a pharmaceutical agent that can be emptied to an exact level of 0.3 ml +/- 5 %. The 0.3 ml pharmaceutical agent remaining in the syringe 20 can be injected into a patient. The tolerance level may be +/- 0.0075 ml. However, the syringe calibration instrument 10 can be dimensioned and adapted for all kind of syringe sizes and different predetermined volumes of content to remain in the syringe 20.
As shown in the different views of Fig. 2, a rear side of the syringe calibration instrument 10 is essentially flat to rest on a work surface. A top surface of the syringe calibration instrument 10 is at one level with a highest point of the syringe barrel 21. The syringe calibration instrument 10 is cone shaped towards the tip end of the syringe 20. The first recess 11 and the second recess 12 are dimensioned to allow a release of the syringe 20 by turning the syringe calibration instrument 10 upside down. The syringe calibration instrument 10 has two essentially semicircular gripping holes 16 arranged along the first recess 11 and soft radiuses to be comfortably handled by the user.
The stopper portion 14 comprises a stopper passage to first allow (position A) and then stop (position B) the movement between the plunger 23 and the barrel 21.
Therefore, a cross section of the stopper passage is compatible to a cross section of a rod 231 of the plunger 23 and incompatible to a cross section of a head 232 of the plunger 23. Here, the cross section of the rod 231 of the plunger 23 is cross-shaped, while the cross section of the head 232 of the plunger 23 is round. Further, the cross section of the stopper passage has a diameter matching to a diameter of the rod 231 to allow the movement of the rod 231 relative to the barrel 21. Furthermore, the diameter of the stopper passage is smaller than a diameter of the head 232 of the plunger 23 to stop the movement of the head 232 relative to the barrel 21.
Fig. 3 shows schematically and exemplarily a detail of one of the views shown in Fig. 2. A spring member 15 is arranged in the second recess 12 for an interaction with the finger flange 2. The spring member 15 is here a unitary part of the syringe calibration instrument 10 and is formed as a spring disc. The spring member 15 pushes the finger flange 2 towards a wall of the second recess 12 to fixedly hold the syringe 20 relative to the syringe calibration instrument 10.
An exemplary handling of the syringe calibration instrument 10 may be as easy as follows: - The syringe calibration instrument 10 lies on a desktop,
- a user inserts the syringe 20 into the syringe calibration instrument 10 and removes a cap of the syringe 20,
- the user makes sure that the plunger 23 is screwed all the way into a plunger stopper,
- the user picks up the syringe calibration instrument 10 and fixes the syringe 20 in the syringe calibration instrument 10 with one hand,
- with the other hand, the user pushes the plunger 23 down the barrel 21 to release a drug surplus or excess solution into e.g. a test tube until the plunger 23 hits the stopper portion 14,
- then, the user removes the syringe 20 with the remaining e.g. 0.3 ml from the syringe calibration instrument 10 by simply turning the syringe calibration instrument 10 upside down with one hand and disposing the syringe 20 into the other hand.
It has to be noted that embodiments of the invention are described with reference to different subject matters. In particular, some embodiments are described with reference to method type claims whereas other embodiments are described with reference to the device type claims. However, a person skilled in the art will gather from the above and the following description that, unless otherwise notified, in addition to any combination of features belonging to one type of subject matter also any combination between features relating to different subject matters is considered to be disclosed with this application.
However, all features can be combined providing synergetic effects that are more than the simple summation of the features.
While the invention has been illustrated and described in detail in the drawings and foregoing description, such illustration and description are to be considered illustrative or exemplary and not restrictive. The invention is not limited to the disclosed embodiments. Other variations to the disclosed embodiments can be understood and effected by those skilled in the art in practicing a claimed invention, from a study of the drawings, the disclosure, and the dependent claims.
In the claims, the word "comprising" does not exclude other elements or steps, and the indefinite article "a" or "an" does not exclude a plurality. A single processor or other unit may fulfil the functions of several items re-cited in the claims. The mere fact that certain measures are re-cited in mutually different dependent claims does not indicate that a combination of these measures cannot be used to advantage. Any reference signs in the claims should not be construed as limiting the scope.

Claims

A syringe calibration instrument (10), comprising:
- a first recess (11) configured to receive a barrel (21) of a syringe (20),
- a second recess (12) configured to receive a finger flange (22) of the syringe (20),
- a movement portion (13) configured to allow a movement of a plunger (23) of the syringe (20) relative to the barrel (21), and
- a stopper portion (14) configured to stop the movement of the plunger (23) relative to the barrel (21),
wherein the first recess (11) and the second recess (12) extend perpendicular to each other to fixedly hold the syringe (20) in a direction along the barrel (21), and wherein the stopper portion (14) is arranged with a predetermined distance relative to the second recess (12) to allow only a limited travel of the plunger (23) in the barrel (21) to retain a predetermined volume in the syringe (20).
Syringe calibration instrument (10) according to claim 1, wherein the stopper portion (14) comprises a stopper passage with a cross section,
wherein the cross section of the stopper passage is compatible to a cross section of a rod (231) of the plunger (23) to allow a movement of the rod (231) relative to the barrel (21), and
wherein the cross section of the stopper passage is incompatible to a cross section of a head (232) of the plunger (23) to stop a movement of the head (232) relative to the barrel (21).
Syringe calibration instrument (10) according to the preceding claim, wherein the cross section of the stopper passage is provided with a diameter,
wherein the diameter of the stopper passage matches to a diameter of the rod (231) of the plunger (23) to allow the movement of the rod (231) relative to the barrel (21), and
wherein the diameter of the stopper passage is smaller than a diameter of the head (232) of the plunger (23) to stop the movement of the head (232) relative to the barrel (21).
4. Syringe calibration instrument (10) according to one of the preceding claims, wherein the first recess (11) and the second recess (12) are dimensioned to receive a barrel (21) with about 8 mm outer diameter and about 1.0 ml volume.
5. Syringe calibration instrument (10) according to the preceding claim, wherein the predetermined distance between the second recess (12) and the stopper portion (14) is dimensioned to keep a predetermined volume of 0.3 ml in the syringe (20).
Syringe calibration instrument (10) according to the preceding claim, wherein the predetermined distance between the second recess (12) and the stopper portion (14) amounts to about 15 mm.
Syringe calibration instrument (10) according to claim 4, wherein the predetermined distance between the second recess (12) and the stopper portion (14) is dimensioned to keep a predetermined volume of 0.45 ml in the syringe (20) and wherein the predetermined distance between the second recess (12) and the stopper portion (14) amounts to about 7 mm.
Syringe calibration instrument (10) according to one of the preceding claims, wherein a spring member (15) is arranged in the second recess (12), wherein the spring member (15) is configured for an interaction with the finger flange (22).
Syringe calibration instrument (10) according to one of the preceding claims, wherein the first recess (11) and the second recess (12) are dimensioned to allow a release of the syringe (20) by turning the syringe calibration instrument (10) upside down.
10. Syringe calibration instrument (10) according to one of the preceding claims, further comprising two essentially semicircular gripping holes (16) arranged along the first recess (11).
11. Syringe calibration instrument (10) according to one of the preceding claims, wherein a front side of the syringe calibration instrument (10) is configured to be essentially flush with the syringe (20).
12. Syringe calibration instrument (10) according to one of the preceding claims, further comprising an adjustment element attached to the stopper portion (14) and configured to adjust the syringe calibration instrument (10) to different syringes and/or different predetermined volumes.
13. Syringe calibration instrument (10) according to one of the preceding claims,
wherein the syringe calibration instrument (10) is made of TECAPEI.
14. A kit (1) comprising a syringe calibration instrument (10) according to one of the preceding claims and a syringe (20) matching into the syringe calibration instrument (10).
15. A method for calibrating a syringe, comprising the following steps:
- inserting a syringe (20) in a syringe calibration instrument (10) according to one of the claims 1 to 13,
- moving a plunger (23) of the syringe (20) relative to a barrel (21) of the syringe (20) until a stopper portion (14) of the syringe calibration instrument (10) stops the movement of the plunger (23) relative to the barrel (21) to retain a predetermined volume in the syringe (20), and
- removing the syringe (20) from the syringe calibration instrument (10) to obtain a calibrated syringe.
PCT/EP2016/057636 2016-04-07 2016-04-07 Syringe calibration instrument WO2017174139A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/EP2016/057636 WO2017174139A1 (en) 2016-04-07 2016-04-07 Syringe calibration instrument
ES201630495U ES1168461Y (en) 2016-04-07 2016-04-21 INSTRUMENT FOR CALIBRATION OF SYRINGES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2016/057636 WO2017174139A1 (en) 2016-04-07 2016-04-07 Syringe calibration instrument

Publications (1)

Publication Number Publication Date
WO2017174139A1 true WO2017174139A1 (en) 2017-10-12

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Application Number Title Priority Date Filing Date
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Country Link
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WO (1) WO2017174139A1 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4357971A (en) * 1980-09-19 1982-11-09 Cyberon Corporation Syringe gauging, loading and injection apparatus
EP0904792A2 (en) * 1997-09-24 1999-03-31 Becton, Dickinson and Company Syringe holder with integral dose divider
WO2012148717A1 (en) * 2011-04-28 2012-11-01 Biogen Idec Ma Inc. A limiter for a dispensing device

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4357971A (en) * 1980-09-19 1982-11-09 Cyberon Corporation Syringe gauging, loading and injection apparatus
EP0904792A2 (en) * 1997-09-24 1999-03-31 Becton, Dickinson and Company Syringe holder with integral dose divider
WO2012148717A1 (en) * 2011-04-28 2012-11-01 Biogen Idec Ma Inc. A limiter for a dispensing device

Also Published As

Publication number Publication date
ES1168461U (en) 2016-10-31
ES1168461Y (en) 2017-01-24

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