WO2017166818A1 - Dispositif portable de surveillance d'électrocardiogramme à distance à 12 dérivations, et système et procédé pour l'appliquer - Google Patents

Dispositif portable de surveillance d'électrocardiogramme à distance à 12 dérivations, et système et procédé pour l'appliquer Download PDF

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Publication number
WO2017166818A1
WO2017166818A1 PCT/CN2016/105118 CN2016105118W WO2017166818A1 WO 2017166818 A1 WO2017166818 A1 WO 2017166818A1 CN 2016105118 W CN2016105118 W CN 2016105118W WO 2017166818 A1 WO2017166818 A1 WO 2017166818A1
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WIPO (PCT)
Prior art keywords
wearable
ecg
lead
electrocardiogram
abnormal
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PCT/CN2016/105118
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English (en)
Chinese (zh)
Inventor
张贯京
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深圳市前海安测信息技术有限公司
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Publication of WO2017166818A1 publication Critical patent/WO2017166818A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A61B5/0006—ECG or EEG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316—Modalities, i.e. specific diagnostic methods
    • A61B5/318—Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/346—Analysis of electrocardiograms
    • A61B5/349—Detecting specific parameters of the electrocardiograph cycle
    • A61B5/366—Detecting abnormal QRS complex, e.g. widening
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203—Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal

Definitions

  • the present invention relates to the field of electrocardiogram monitoring, and in particular, to a wearable 12-lead remote ECG monitoring device and an application system and method thereof.
  • Heart disease is one of the major diseases that seriously threaten human health, and ECG signals contain important physiological parameters of the human body. Therefore, electrocardiogram (ECG) is an important basis for diagnosis.
  • ECG electrocardiogram
  • Heart disease has a sudden nature. The most ideal situation is the actual signal acquisition and analysis of patients with heart disease.
  • the diagnosis and treatment of the disease is extremely unfavorable. Therefore, there is an urgent need for an inexpensive and practical ECG detection instrument to reduce medical expenses and strengthen the monitoring work during the patient's illness.
  • the familyization of portable medical devices has become a development trend of medical electronics.
  • Existing devices for detecting human electrocardiogram include electrocardiographs such as electrocardiographs and dynamic electrocardiographs.
  • ECG testing instruments are commonly used in hospitals or other medical research institutions, ECG testing instruments currently have the following disadvantages: large size, large workload, complicated operation, long consumption, and high cost.
  • the ECG data collected by the existing ECG detection system is mostly stored locally, and the ECG data cannot be connected to the medical center, and the remote synchronization monitoring of the patient's ECG cannot be realized. Therefore, at present, ECG testing equipment can not continuously monitor the electrocardiogram of patients with heart disease continuously for 24 hours a day, so that doctors can remotely track the ECG data of heart patients, this is for doctors and heart disease. Patients are very inconvenient in daily ECG detection and tracking.
  • the main objective of the present invention is to provide a wearable 12-lead remote ECG monitoring device and an application system and method thereof, aiming at solving the problem that the ECG detection system cannot remotely and dynamically monitor the patient's ECG information. And can not filter out the problem of abnormal ECG.
  • the present invention provides a wearable 12-lead remote ECG monitoring device, including a wearable body, an electrode interface, twelve cardiac electrodes, lead wires, and an electrocardiogram analysis unit.
  • One of the core electrode sheets is disposed on the back surface of the wearable body, and the other eleven core electrode sheets are connected together through the lead wire and connected to the electrode interface, and the electrode interface is connected to the core On the electrical analysis unit, where:
  • each of the core electrodes is used to collect the ECG signal of the subject, and the collected ECG signals are sent to the electrode interface through the lead wires;
  • the electrocardiogram analyzing unit is configured to acquire an electrocardiogram signal of the subject from the electrode interface, obtain an electrocardiogram waveform by using signal sampling analysis, and filter out an abnormal ECG waveform segment of the detected object, and The abnormal ECG waveform segment is converted into an abnormal electrocardiogram of the subject.
  • the wearable 12-lead remote ECG monitoring device further includes a display screen connected to the electrocardiographic analysis unit, the display screen is disposed on a front surface of the wearable body, The ECG waveform and abnormal ECG of the subject are displayed.
  • the wearable 12-lead remote ECG monitoring device further comprises a wireless communication interface connected to the ECG analysis unit, the wireless communication interface is a Bluetooth or/and WiFi wireless transmission network. Communication port.
  • the twelve cardiac electrode sheets comprise three limb lead electrodes, three pressurized lead electrodes and six chest lead electrodes.
  • the electrode interface is a USB data interface or a serial data interface.
  • the edge of the wearable body is symmetrically disposed with two straps, and the adhesive surface of the strap is provided with a medical adhesive.
  • the present invention further provides an application system for applying a wearable 12-lead remote ECG monitoring device, the application system further comprising the mobile communication terminal and a medical monitoring platform, the wearable a 12-lead remote ECG monitoring device connected to the mobile communication terminal via a wireless network, the mobile communication terminal being connected to the medical monitoring platform via a remote communication network, the wearable 12-lead remote ECG
  • the monitoring device transmits an abnormal electrocardiogram of the subject to the medical monitoring platform through the mobile communication terminal.
  • the present invention further provides a wearable 12-lead remote ECG monitoring method, which is applied to a wearable 12-lead remote ECG monitoring device, the device comprising a wearable body, An electrode interface, twelve core electrode sheets, lead wires, and an electrocardiogram analyzing unit, wherein one core electrode sheet is disposed on a back surface of the wearable body, and another eleven core electrode sheets are connected through the lead wires And connected to the electrode interface, the electrode interface is connected to the ECG analyzing unit, and the wearable 12-lead remote ECG monitoring method comprises the steps of:
  • each cardiac electrode sheet collects the ECG signal of the subject, and sends the collected ECG signal to the electrode interface through the lead line;
  • the electrocardiogram analyzing unit acquires an electrocardiogram signal of the subject from the electrode interface, and obtains an electrocardiogram waveform by using signal sampling analysis processing;
  • the electrocardiographic analysis unit screens out an abnormal ECG waveform segment of the subject, and converts the abnormal ECG waveform segment into an abnormal electrocardiogram of the subject;
  • the ECG analyzing unit transmits the abnormal electrocardiogram of the subject to the mobile communication terminal of the guardian through the wireless communication interface.
  • the electrocardiographic analysis unit filters out the abnormal ECG waveform segment of the detected object, including the following steps: preprocessing the electrocardiographic waveform to eliminate part of noise and interference; using differential threshold method for pre-processing The waveform performs R point detection and stores detection information; the Toskins difference method is used to detect and store the width of the QRS complex; and the branch logic method is used to perform an arrhythmia event to determine an abnormal ECG waveform segment.
  • the wearable 12-lead remote ECG monitoring method further comprises the steps of: the mobile communication terminal transmitting the abnormal electrocardiogram of the detected person to the medical monitoring set in the remote medical center through the remote communication network; on the platform.
  • the wearable 12-lead remote ECG monitoring device and the application system and method thereof can dynamically monitor the heart of a patient 24 hours a day, 24 hours a day. Electrical information and abnormal electrocardiogram, for the doctor to remotely track the patient's ECG information and ECG abnormalities, providing great convenience for doctors to remotely monitor the patient's ECG.
  • FIG. 1 is a schematic front view showing a preferred embodiment of a wearable 12-lead remote ECG monitoring device of the present invention
  • FIG. 2 is a schematic view showing the back structure of a preferred embodiment of the wearable 12-lead remote ECG monitoring device of the present invention
  • FIG. 3 is a schematic diagram showing the circuit structure of a preferred embodiment of the wearable 12-lead remote ECG monitoring device of the present invention.
  • FIG. 4 is a system architecture diagram of a preferred embodiment of an application system of the wearable 12-lead remote ECG monitoring device of the present invention
  • FIG. 5 is a flow chart of a preferred embodiment of the wearable 12-lead remote ECG monitoring method of the present invention.
  • FIG. 1 is a front elevational view showing a preferred embodiment of a wearable 12-lead remote ECG monitoring device of the present invention.
  • Fig. 2 is a schematic view showing the back structure of a preferred embodiment of the wearable 12-lead remote ECG monitoring device of the present invention.
  • the wearable 12-lead remote ECG monitoring device 10 includes a wearable body 1 and two straps 2 disposed on the edge of the wearable body 1, the strap 2 They are symmetrically disposed on opposite sides of the wearable body 1, respectively.
  • the wearable body 1 is made of a lightweight metal material or a hard rubber.
  • the shape of the wearable body 1 may be, but not limited to, a rectangular shape, a square shape, a circular shape or the like.
  • the shape of the wearable body 1 in the present embodiment is a rectangle.
  • the adhesive surface of the strap 2 is provided with a medical adhesive so that the strap 2 can be attached to the skin of the human chest without falling off.
  • the wearable 12-lead remote ECG monitoring device 10 further includes an electrode interface 3, a plurality of core electrode sheets 4, and a lead wire 5.
  • the electrode interface 3 can be a USB interface or a serial port receiving unit .
  • the core electrode sheet 4 includes three limb lead electrodes, three pressurized lead electrodes, and six chest lead electrodes for acquiring an electrocardiographic signal of the subject.
  • one of the core electrode sheets 4 is disposed on the back surface of the wearable body 1 (refer to FIG. 2), and the remaining eleven core electrode sheets 4 (only seven are shown in FIG. 1) are passed through the lead. Lines 5 are connected together and connected to electrode interface 3 (refer to Figure 1).
  • the core electrode sheet 4 disposed on the back of the wearable body 1 is used for directly collecting the ECG signals of the human chest, and is connected by the lead wires 5 together.
  • the core electrode sheets 4 can be respectively adsorbed on the parts of the human body to be detected, such as the underarm, the neck, the abdomen, etc., for collecting the electrocardiographic signals of the parts to be detected.
  • the wearable 12-lead remote ECG monitoring device 10 of the present invention has a small volume, and after the subject performs an electrocardiographic test, the wearable body 1 is pasted to the chest position by the strap 2, The core electrode sheets 4 connected together by the lead wires 5 are respectively adsorbed on the parts to be detected by the human body, so that the testees can be conveniently carried around with them, and the operation is simple, thereby facilitating the operation of the test subject. .
  • twelve ECG sheets 4 are used to collect ECG signals of different body parts of the subject, and one of the core electrode sheets 4 is disposed on the back surface of the wearable body 1, it can be directly adsorbed together with the wearable body.
  • the chest of the subject can accurately collect the ECG signal of the chest of the subject, thereby improving the accuracy of the ECG detection result.
  • FIG. 3 is a schematic diagram showing the circuit structure of a preferred embodiment of the wearable 12-lead remote ECG monitoring device 10 of the present invention.
  • the wearable 12-lead remote ECG monitoring device 10 further includes a power switch 11, a display screen 12, an electrocardiogram analyzing unit 13, and a micro battery 14.
  • a power supply switch 11 and a display screen 12 are disposed on the front surface of the wearable body 1, and are electrically connected to the electrocardiographic analysis unit 13.
  • the electrocardiographic analysis unit 13 and the microbattery 14 are disposed inside the wearable body 1 , and the micro battery 14 is electrically connected to the electrocardiographic analysis unit 13 for the wearable twelve guide
  • the remote telecardiograph 10 provides operational power.
  • the core electrode sheet 4 is connected to the electrode interface 3 via a lead wire 5, which is electrically connected to the electrocardiographic analysis unit 13.
  • the core electrode sheet 4 is configured to collect various ECG signals of different parts of the body of the subject, and send the collected ECG signals to the electrode interface 3 through the lead wire 5.
  • the ECG analyzing unit 13 is configured to acquire each ECG signal of the detected object from the electrode interface 3, and obtain an ECG waveform by using signal sampling analysis processing.
  • the abnormal electrocardiographic waveform segment of the subject is screened, and the abnormal ECG waveform segment is converted into an abnormal electrocardiogram of the subject.
  • the electrocardiogram analyzing unit 13 samples the respective electrocardiographic signals of the electrode interface 3 to obtain a lead electrocardiographic waveform by sampling a chirp and converting a chirp.
  • the electrocardiogram analyzing unit 13 can control the sampling rate by changing the sampling clock. For example, if the ECG analyzing unit 13 samples once every 0.5 ms or 1 ms or 2 ms, the sampling rates of the corresponding ECG signals are 2 KSps, IKsps, and 500 Sps, respectively.
  • the power switch 11 is configured to activate or disable the wearable 12-lead remote ECG monitoring device 10 for ECG detection.
  • the display screen 12 is an LCD or LED display unit for displaying the electrocardiogram waveform and the abnormal electrocardiogram of the subject.
  • the wearable 12-lead remote ECG monitoring device 10 further includes a wireless communication interface 6 disposed on the wearable body 1.
  • the wireless communication interface 6 is a communication interface supporting a Bluetooth, WiFi, GSM, GPRS. 3G or 4G wireless transmission network, and is used for transmitting the ECG signal of the detected person to the mobile communication terminal of the guardian or the doctor (for example, monitoring On the mobile phone of the doctor or the doctor, for the guardian to dynamically understand the electrocardiogram of the subject.
  • the micro battery 14 is used for providing the working power supply to the wearable 12-lead remote ECG monitoring device 10, which is a low-radiation, low-power rechargeable lithium battery or button battery. , it will not affect the health of users.
  • the charging port 7 is also connected to the wearable body 1.
  • the charging port 7 can be a USB charging interface, and the charging port can be a USB interface or the like.
  • a standard battery charging interface that can be directly plugged into an external power source (such as a computer USB interface or a low voltage regulator, etc.) to charge the miniature battery 14.
  • the power of the microbattery 14 When the power of the microbattery 14 is used up, the user can charge the microbattery 14 through the charging port, thereby extending the life cycle of the wearable 12-lead remote ECG monitoring device 10.
  • FIG. 4 is a structural diagram of an application system of a preferred embodiment of a system for a wearable 12-lead remote ECG monitoring device of the present invention.
  • the application system includes a wearable 12-lead remote ECG monitoring device 10, a mobile communication terminal 20, and a medical monitoring platform 30.
  • the wearable 12-lead telecardiograph 10 is connected to the mobile communication terminal 20 via a wireless network 40, which is connected to the medical monitoring platform 30 via a remote communication network 50.
  • the wireless network 40 includes, but is not limited to, a wireless transmission network such as Bluetooth, WiFi, etc.
  • the remote communication network 50 includes but not It is limited to wireless transmission networks such as GSM network, GPRS network, and CDMA.
  • the wearable 12-lead telecardiograph 10 is a chest position worn by a subject (eg, a heart patient).
  • the mobile communication terminal 20 includes, but is not limited to, a wireless communication device such as a mobile phone, a personal digital assistant (PDA), a palmtop computer, or the like.
  • the medical monitoring platform 30 is a remote monitoring device or server or the like disposed at the medical monitoring center.
  • the wearable 12-lead remote ECG monitoring device 10 is configured to dynamically collect the ECG signal of the subject and form an electrocardiogram 24 hours a day.
  • the electrocardiogram of the examiner is transmitted to the mobile communication terminal 20 via the wireless network 40 for display, so that the guardian can dynamically understand the electrocardiogram of the subject.
  • the mobile communication terminal 20 transmits the electrocardiogram of the subject to the medical monitoring platform 30 disposed at the medical monitoring center via the remote communication network 50, so that the doctor can remotely track the electrocardiogram of the subject remotely.
  • the wearable 12-lead remote ECG monitoring device 10 of the present invention transmits the collected ECG data to the external mobile communication terminal 20, and then is sent by the external mobile communication terminal 20 to the remote medical monitoring platform. 30 0 is stored, thereby realizing the connection between the ECG data and the medical center, and realizing the remote synchronous monitoring of the patient's electrocardiogram by the doctor. This allows doctors to monitor the electrocardiogram of heart disease patients 24 hours a day, 24 hours a day, and it is convenient for doctors to remotely track cardiac data of heart patients in daily ECG testing. In addition, since the external mobile communication terminal 20 is used as the transmitting ECG data to the remote medical monitoring platform 30, the hardware configuration requirements of the wearable 12-lead remote ECG monitoring device 10 of the present invention are reduced. It saves costs and realizes remote synchronous monitoring of ECG data.
  • the present invention also provides a wearable 12-lead remote ECG monitoring method, which is applied to the wearable 12-lead remote ECG monitoring device 10, and can accurately screen out the detected object.
  • the abnormal electrocardiogram is sent to the external mobile communication terminal 20 and the remote medical monitoring platform 30 for the doctor to remotely track the patient's ECG condition in the daily ECG detection.
  • FIG. 5 is a flow chart of a preferred embodiment of the wearable 12-lead remote ECG monitoring method of the present invention.
  • the wearable 12-lead remote ECG monitoring method includes the following steps:
  • each ECG sheet 4 collects an ECG signal of the subject, and sends the collected ECG signal to the electrode interface 3 through the lead wire 5.
  • the electrocardiogram analyzing unit 13 acquires the ECG signal of the subject from the electrode interface 3, and obtains an electrocardiogram waveform by the signal sampling analysis process.
  • the electrocardiographic analysis unit 13 samples the electrocardiographic signals of the electrode interfaces 3 by sampling the chirp clock and converting the chirp clock to obtain a lead electrocardiogram waveform.
  • the electrocardiogram analyzing unit 13 can control the sampling rate by changing the sampling clock. For example, if the ECG analysis unit 13 samples every 0.5 ms or 1 ms or 2 ms, the sampling rates of the corresponding ECG signals are 2 KSps, IKsps, and 500 Sps, respectively.
  • Step S53 the electrocardiogram analyzing unit 13 filters out the abnormal ECG waveform segment of the subject, and converts the abnormal ECG waveform segment into an abnormal electrocardiogram of the subject.
  • the electrocardiographic analysis unit 13 can automatically identify patients with abnormal ECG information by screening abnormal ECG waveform segments, thereby improving the efficiency and accuracy of the doctor in screening patients with abnormal electrocardiogram.
  • the step of filtering the abnormal ECG waveform segment of the detected object by the electrocardiogram analyzing unit 13 comprises the following steps: preprocessing the electrocardiographic waveform to eliminate part of noise and interference; using differential threshold method for preprocessing The waveform after the R point is detected and the detection information is stored; the width of the Q RS group is detected and stored by Tompkins; and the arrhythmia event is determined by the branch logic method to determine the abnormal ECG waveform segment.
  • the conventional ECG waveform is QRS complex, which reflects the depolarization process of the left and right ventricles in a certain order, with a history of 0.06 ⁇ 0.10s.
  • the first downward wave in the QRS complex is called the Q wave
  • the first upward wave is called the R wave
  • the downward wave after the R wave is called the S wave.
  • the differential threshold method is to realize the QRS complex positioning by detecting the derivative of the ECG signal sequence, that is, the change of the slope.
  • the Tompkins difference method is to use the forward difference to find the absolute value of the first-order differential, and the backward difference to find the absolute value of the second-order differential, and then use five-point average filtering to smooth-rect them separately. The results are directly added to obtain a waveform with a double peak.
  • the branch logic method is based on the experience of doctors and experts, based on the extracted ECG feature values and the doctor's expert experience threshold for logical relationship calculation.
  • Step S54 the electrocardiogram analyzing unit 13 sends the abnormal electrocardiogram of the detected person to the mobile communication terminal 20 of the guardian through the wireless communication interface 6, so that the guardian can perform emergency ambulance measures on the detected subject, for example, dial 120. Inform medical personnel for emergency care.
  • Step S55 the mobile communication terminal 20 transmits the abnormal electrocardiogram of the detected person to the medical monitoring platform 30 disposed at the remote medical center through the remote communication network 50, so that the doctor can remotely track the heart of the detected subject.
  • the situation is urgently ambulanced for patients with abnormal ECG.
  • the wearable 12-lead remote ECG monitoring device and the application system and method thereof can dynamically monitor the heart of a patient 24 hours a day, 24 hours a day. Electrical information and abnormal electrocardiogram, for the doctor to remotely track the patient's ECG information and ECG abnormalities, providing great convenience for doctors to remotely monitor the patient's ECG.

Abstract

L'invention concerne un dispositif portable de surveillance d'électrocardiogramme à distance à 12 dérivations (10), et un système et un procédé pour l'appliquer. Le dispositif (10) comprend : un corps portable (1), une interface d'électrode (3), douze éléments polaires électrocardiographiques (4), des fils de sortie (5) et une unité d'analyse électrocardiographique (13), dans lequel un élément polaire électrocardiographique (4) est disposé à l'arrière du corps portable (1), et les onze autres éléments polaires électrocardiographiques (4) sont connectés ensemble par l'intermédiaire des fils de sortie (5) et sont connectés à l'interface d'électrode (3) ; et l'interface d'électrode (3) est connectée à l'unité d'analyse électrocardiographique (13). Chaque élément polaire électrocardiographique (4) est utilisé pour collecter un signal électrocardiographique d'un sujet; et l'unité d'analyse électrocardiographique (13) acquiert le signal électrocardiographique du sujet à partir de l'interface d'électrode (3), obtient une forme d'onde électrocardiographique au moyen d'un échantillonnage de signal et d'un traitement analytique, extrait un segment de forme d'onde électrocardiographique anormal du sujet, et convertit le segment de forme d'onde électrocardiographique anormale en un électrocardiogramme anormal du sujet. Le dispositif peut surveiller de façon dynamique l'état électrocardiographique d'un patient pendant un jour entier sans interruption, ce qui est pratique pour un médecin en termes de surveillance à distance de l'état électrocardiographique du patient.
PCT/CN2016/105118 2016-03-26 2016-11-08 Dispositif portable de surveillance d'électrocardiogramme à distance à 12 dérivations, et système et procédé pour l'appliquer WO2017166818A1 (fr)

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CN201610178072.4 2016-03-26
CN201610178072.4A CN105852845A (zh) 2016-03-26 2016-03-26 可穿戴式十二导联远程心电监护装置及其应用系统和方法

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