WO2017166692A1

WO2017166692A1 - Blood gas analyzer and blood gas biochemical test card thereof

Info

Publication number: WO2017166692A1
Application number: PCT/CN2016/097623
Authority: WO
Inventors: 朱志华; 王继华
Original assignee: 广州万孚生物技术股份有限公司
Priority date: 2016-03-31
Filing date: 2016-08-31
Publication date: 2017-10-05
Also published as: CN106483178A

Abstract

A blood gas analyzer and a blood gas biochemical test card thereof, at least comprising: a pressing member (10), a test card body (20), a liquid pipe (210) provided on the test card body (20), and a flexible member which is connected to the test card body (20) and seals the liquid pipe (210). The surface of the liquid pipe (210) opposite to the flexible member is provided with a groove (211), and the flexible member is located between the groove (211) and the pressing member (10). The pressing member (10) is provided with a pressing head (110), the shape of which matches with the shape of the groove (211). The groove (211) is provided inside the liquid pipe (210) and together with the liquid pipe (210) forms a whole, without a redundant empty chamber, and without any bubbles remaining, the usage amount of the test liquid is reduced, and the test accuracy is improved. There is no need to provide a pipe switching rubber plug and a sealing film for covering the pipe switching rubber plug on the test card body (20), the problem of gas leakage is avoided, the number of components is reduced, the production is facilitated and the product failure rate is reduced.

Description

Blood gas analyzer and blood gas biochemical test card

Technical field

The invention relates to the technical field of medical technology, in particular to a blood gas analyzer and a blood gas biochemical test card thereof.

Background technique

The blood gas biochemical test card is widely used in the medical industry. The test card integrates the biochemical test electrode, and is calibrated by the calibration liquid in the reagent package, and then the test liquid is tested. The blood gas biochemical test card generally introduces the test liquid through a liquid pipe, and opens or closes the liquid pipe by providing an on/off switch rubber plug on the test card main body. In order to prevent liquid leakage, a sealing film is generally adhered on the test card main body for the liquid. Covering the channel switch rubber plug, the sealing film is prone to the problem of air leakage caused by poor bonding, and since the channel switch rubber plug protrudes from the surface of the test card body, a large cavity needs to be reserved for the sealing film arching position, and the test liquid cannot be The cavity is completely filled, and air bubbles are easily left in the cavity, and the air bubbles are easily exchanged with the test liquid, which easily affects the test result.

Summary of the invention

The object of the present invention is to provide a blood gas analyzer and a blood gas biochemical test card thereof, which can avoid the problem of air leakage, improve the test accuracy, and facilitate production.

In order to achieve the object of the present invention, the technical solution adopted is:

A blood gas biochemical test card comprises at least a pressing member, a test card main body, a liquid pipe disposed on the main body of the test card, an elastic member connected to the test card main body and sealing the liquid pipe, and the opposite side of the liquid pipe and the elastic member is provided a groove, the first elastic member is located between the groove and the pressing member, and the pressing member is provided with a pressing head matching the shape of the groove.

When the test card draws the standard liquid, the pressing member moves toward the groove side, and after the pressing head presses the first elastic member, the elastic member is driven to move toward the groove side, and the pressing head moves to fit the groove. The elastic member is pressed between the pressing head and the groove, and the elastic member is filled with the elastic deformation of the elastic member to the groove, so that the liquid pipe is closed; After the test card is calibrated by the calibration liquid, when the test liquid is pumped, the pressing member moves toward the side far away from the groove, and gradually leaves the first elastic member until the external force on the elastic member is eliminated, and the elastic member is itself The elastic deformation causes the elastic member to leave the groove, the liquid pipe is opened, and the test liquid flows into the test portion of the test card through the liquid pipe. The groove is arranged in the liquid pipe, and is integrated with the liquid pipe, there is no excess cavity, no air bubbles remain, and the amount of the test liquid is reduced, and the test accuracy is improved; no on-off switch rubber plug is needed on the test card body and is used for covering The sealing membrane of the channel switch rubber plug avoids gas leakage problems, reduces the number of parts, facilitates production, and reduces product defect rate.

The technical solution is further explained below:

Further, the bottom of the groove is provided with a protrusion protruding toward one side of the first elastic member. When the elastic member is filled into the groove, the protrusion is embedded in the elastic member, so that the sealing effect of the liquid pipe is better.

Further, the elastic member includes a first elastic member covering the groove, and a second elastic member attached to a side of the first elastic member facing away from the groove. When the indenter is moved to the groove, the first elastic member on the elastic member is pressed between the pressing head and the groove, and the first elastic member is filled onto the groove by the elastic deformation of the first elastic member to close the liquid pipe; After the test card is calibrated by the calibration liquid, when the test liquid is pumped, the pressing member moves toward the side away from the groove, and gradually leaves the elastic member until the external force on the elastic member is eliminated, and the elastic member is second elastic. The elastic recovery of the piece drives the first elastic member to leave the groove, and the second elastic member functions as a support and a reset to prevent the first elastic member from being deformed while ensuring effective resetting of the first elastic member after the external force is removed, so that the first elastic The reset effect of the piece is better.

Further, the first elastic film is an elastic silicone film, and the second elastic member is a PET film. The silicone film has strong elastic deformation ability and long service life, prolonging the service life of the test card; the PET film has excellent mechanical properties, strong toughness, tensile strength and impact resistance, and good reset deformation effect.

Further, the elastic film further comprises a film, and a film is adhered between the test card body and the first elastic member. The first elastic member is bonded to the test card body through the adhesive film to facilitate production assembly.

Further, the groove is a spherical groove, and the indenter is a spherical indenter. The surface of the spherical groove is a curved surface, so that the first elastic member can be more easily filled into the groove, so that the sealing effect of the liquid pipe is better.

The invention also provides a blood gas analyzer, comprising a reagent package, a pump and a blood gas biochemical test card, the blood gas biochemical test card is provided with a calibration liquid port connected with the reagent package, an air suction port connected to the pump, and a calibration liquid port. And the suction port is connected to one end of the liquid pipe.

When the standard solution is drawn, the blood gas biochemical test card closes the liquid pipeline through the pressing member, and the suction port is connected with the pump. After the pump is energized, the negative pressure is generated in the test card pipeline, and the reagent package works to make the calibration liquid pass the calibration liquid. The mouth flows from the reagent bag into the test site of the blood gas biochemical test card; after the calibration is completed, the pump continues to work, so that the calibration liquid is pumped away from the test portion of the test card, the pressing member leaves the groove, and the test liquid flows into the test under the action of the negative pressure. The test part of the card and the test part are tested on the test liquid, and the blood gas analyzer test with the blood gas biochemical test card is more accurate.

Further, the blood gas analyzer further includes a driving device that drives the ram to reciprocate toward one side of the groove. The movement of the pressing member is driven by the driving device to make the operation of the blood gas analyzer simpler.

Further, the driving device is a motor and the pump is a vacuum pump.

Compared with the prior art, the present invention has the following beneficial effects:

The groove of the invention is arranged in the liquid pipeline, and is integrated with the liquid pipeline, does not have excess cavity, does not leave air bubbles, reduces the amount of the test liquid, improves the test accuracy; does not need to provide an on/off switch rubber plug and the test card body The sealing film covering the channel switch rubber plug avoids gas leakage problems, reduces the number of parts, facilitates production, and reduces product defect rate.

DRAWINGS

1 is a schematic structural view of a blood gas biochemical test card according to an embodiment of the present invention;

Figure 2 is a cross-sectional view taken along line A-A of Figure 1;

Figure 3 is an enlarged view of I of Figure 2;

4 is a schematic view showing a first working state of a pressing member and a groove according to an embodiment of the present invention;

5 is a schematic view showing a second working state of a pressing member and a groove according to an embodiment of the present invention;

Fig. 6 is a schematic structural view of a blood gas analyzer according to an embodiment of the present invention.

Description of the reference signs:

10. Pressing parts, 110. Indenter, 20. Test card body, 210. Liquid piping, 211. Groove, 220. Protrusion, 230. Calibration liquid port, 240. Pumping port, 250. Inlet, 30. First elastic member, 40. film, 50. second elastic member, 60. syringe, 70. electrode circuit board, 80. reagent pack, 90. pump.

detailed description

The embodiments of the present invention are described in detail below with reference to the accompanying drawings:

As shown in FIG. 1 to FIG. 3, a blood gas biochemical test card includes at least a pressing member 10, a test card main body 20, a liquid pipe 210 disposed on the test card main body 20, and a test card main body 20 connected to the liquid pipe. The elastic member of the 210, the liquid pipe 210 and the first elastic member are provided with a groove 211, and the elastic member is located between the groove 211 and the pressing member 10. The pressing member 10 is provided with a pressure matching with the shape of the groove 211. In the head 110, the elastic member includes a first elastic member 30 covering the groove 211, and a second elastic member 50 attached to a side of the first elastic member 30 facing away from the groove, the first elastic member 30 and the second elastic member The piece 50 is hot pressed to form an elastic composite film.

When the test card draws the standard liquid, as shown in FIG. 4, the pressing member 10 moves toward the side of the groove 211, and after the pressing head 110 presses the second elastic member 50 and the first elastic member 30, the second elastic member 50 is driven. The first elastic member 30 is pressed between the pressing head 110 and the groove 211, and the first elastic member is moved toward the side of the groove 211 together with the first elastic member 30. When the pressing head 110 is moved to be engaged with the groove 211, the first elastic member 30 is pressed between the pressing head 110 and the groove 211. 30 is filled on the groove 211 by its own elastic deformation, so that the liquid pipe 210 is closed; after the test card is finished calibration by the calibration liquid, when the test liquid is pumped, as shown in FIG. 5, the pressing member 10 is away from the groove. One side of the 211 moves and gradually leaves the second elastic member 50 and the first elastic member 30 until the external force on the second elastic member 50 is eliminated, and the second elastic member 50 is deformed by itself to cause the first elastic member 30 to leave. The groove 211 opens the liquid pipe 210, and the test liquid flows into the test portion of the test card through the liquid pipe 210. The second elastic member 50 serves as a supporting and resetting function to prevent the first elastic member 30 from being deformed, and to ensure effective resetting of the first elastic member 30 after the external force is removed, so that the first elastic member 30 has a better reset effect; The 211 is disposed in the liquid pipe 210 and is integrated with the liquid pipe 210. There is no excess cavity, no air bubbles remain, and the amount of the test liquid is reduced, and the test accuracy is improved; the test card body 20 does not need to be provided with an on/off switch rubber plug and The sealing film covering the channel switch rubber plug avoids gas leakage problems, reduces the number of parts, facilitates production, and reduces product defect rate.

In the embodiment, the first elastic member 30 is an elastic silicone film 40. The silicone film 40 has strong elastic deformation capability, long service life, prolongs the service life of the test card, and the first elastic member 30 adopts a flat surface. And the large-surface film sealing method seals the pipe in the whole test card to further avoid the air leakage problem; the second elastic member 50 is a PET film, and the PET film has excellent mechanical properties, strong toughness, tensile strength and impact resistance, and reset deformation The effect is good. The second elastic member 50 can also be made of other materials according to actual needs. The first elastic member 30 and the second elastic member 50 can also be made of other materials according to actual needs. The elastic member may also be configured to be composed of at least one layer of elastic members according to actual needs.

As shown in FIG. 3, a film 40 is adhered between the test card body 20 and the first elastic member 30, and the position of the film 40 opposite to the groove 211 is partially hollowed out to prevent the film 40 from being adhered to the groove 211 and the protrusion. On the portion 220, the problem that the first elastic member 30 cannot rebound is caused. The first elastic member 30 is bonded to the test card main body 20 through the adhesive film 40 to facilitate production assembly. The test liquid channel 210 can also be sealed between the test card body 20 and the first elastic member 30 by other connection means.

As shown in FIG. 3, the bottom of the groove 211 is provided with a protrusion 220 which is convex toward the side of the first elastic member 30, and the protrusion 220 has a rib shape. When the first elastic member 30 is filled into the recess 211, the protruding portion 220 is fitted into the first elastic member 30, so that the sealing effect of the liquid conduit 210 is better.

In the present embodiment, the groove 211 is a spherical groove, and the ram 110 is a spherical ram 110. The surface of the spherical groove is a curved surface, so that the first elastic member 30 is more easily filled onto the groove 211, so that the sealing effect of the liquid pipe 210 is better. The groove 211 and the ram 110 can also be set to other shapes according to actual needs. As shown in FIG. 1, the blood gas biochemical test card further includes a sample needle 60 and an electrode circuit board 70. The electrode circuit board 70 is bonded to the other side of the test card body 20 facing the liquid pipe 210 through the film 40, the sample needle 60 is attached to the inlet 250 of the test card body 20 and is in communication with a syringe or capillary, and the test fluid is stored in a syringe or capillary.

As shown in FIG. 6, the present invention further provides a blood gas analyzer comprising a reagent package 80, a pump 90 and a blood gas biochemical test card, and the blood gas biochemical test card is provided with a calibration liquid port 230 connected to the reagent package 80, and a pump 90. The connected suction port 240, the calibrating liquid port 220, and the suction port 240 are both in communication with one end of the liquid pipe 210.

When the standard liquid is drawn, the blood gas biochemical test card closes the liquid pipe 210 through the pressing member 10, and the suction port 240 communicates with the pump 90. After the pump 90 is energized, the negative pressure is generated in the test card pipe, and the reagent bag 80 works. The standard liquid flows from the reagent bag 80 into the blood gas biochemical test card through the calibration liquid port 220. Test part; after the calibration is completed, the pump 90 continues to work to draw the calibration liquid away from the test portion of the test card, the pressing member 10 leaves the groove 211, and the test liquid flows into the test portion of the test card under the action of the negative pressure, and the test portion The test liquid is tested, and the blood gas analyzer with the blood gas biochemical test card is more accurate.

The blood gas analyzer further includes a driving device (not shown) that drives the ram 110 to reciprocate toward the side of the recess 211. The operation of the pressure member 10 is driven by the driving device to make the operation of the blood gas analyzer simpler.

In the present embodiment, the driving device is a motor and the pump 90 is a vacuum pump 90. The drive unit and pump 90 can also be configured in other forms as needed.

The technical features of the above-described embodiments may be arbitrarily combined. For the sake of brevity of description, all possible combinations of the technical features in the above embodiments are not described. However, as long as there is no contradiction between the combinations of these technical features, All should be considered as the scope of this manual.

The above-described embodiments are merely illustrative of several embodiments of the present invention, and the description thereof is more specific and detailed, but is not to be construed as limiting the scope of the invention. It should be noted that those skilled in the art can also make the protection scope of the present invention if dry deformation and improvement are made without departing from the inventive concept. Therefore, the scope of the invention should be determined by the appended claims.

Claims

A blood gas biochemical test card, comprising: at least a pressing member, a test card body, a liquid pipe disposed on the test card body, and an elastic member connected to the test card body and sealing the liquid pipe, The liquid pipe is provided with a groove on an opposite surface of the elastic member, the elastic member is located between the groove and the pressing member, and the pressing member is provided to match the shape of the groove. Indenter.
The blood gas biochemical test card according to claim 1, wherein the bottom of the groove is provided with a protrusion that is convex toward one side of the elastic member.
The blood gas biochemical test card according to claim 1, wherein the elastic member comprises a first elastic member covering the groove, and attached to the first elastic member facing away from the groove a second elastic member on one side.
The blood gas biochemical test card according to claim 3, wherein the first elastic member is an elastic silicone film, and the second elastic member is a PET film.
The blood gas biochemical test card according to claim 3, wherein the elastic member further comprises a film, and the film is adhered between the test card body and the first elastic member.
The blood gas biochemical test card according to any one of claims 1 to 5, wherein the groove is a spherical groove, and the indenter is a spherical indenter.
A blood gas analyzer, comprising: a reagent package, a pump, and the blood gas biochemical test card according to any one of claims 1 to 6, wherein the blood gas biochemical test card is provided with a calibration connection with the reagent package a liquid port, an air suction port connected to the pump, the calibration liquid port and the air suction port are both in communication with one end of the liquid pipe.
A blood gas analyzer according to claim 7, further comprising driving means for driving said ram to reciprocate toward one side of said groove.
A blood gas analyzer according to claim 8, wherein said driving means is a motor and said pump is a vacuum pump.