WO2017150368A1 - Dispositif de diagnostic par ultrasons et procédé de traitement d'informations ultrasonores - Google Patents

Dispositif de diagnostic par ultrasons et procédé de traitement d'informations ultrasonores Download PDF

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Publication number
WO2017150368A1
WO2017150368A1 PCT/JP2017/007055 JP2017007055W WO2017150368A1 WO 2017150368 A1 WO2017150368 A1 WO 2017150368A1 JP 2017007055 W JP2017007055 W JP 2017007055W WO 2017150368 A1 WO2017150368 A1 WO 2017150368A1
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Prior art keywords
balance
strain
distortion
information
distribution
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PCT/JP2017/007055
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English (en)
Japanese (ja)
Inventor
一也 高木
義浩 武田
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コニカミノルタ株式会社
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Application filed by コニカミノルタ株式会社 filed Critical コニカミノルタ株式会社
Priority to CN201780013168.8A priority Critical patent/CN108697405A/zh
Priority to JP2018503098A priority patent/JP6662448B2/ja
Publication of WO2017150368A1 publication Critical patent/WO2017150368A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings

Definitions

  • the present invention relates to an ultrasonic diagnostic apparatus and an ultrasonic information processing method.
  • an ultrasonic diagnostic apparatus that can observe tissue structure and properties by irradiating an ultrasonic wave inside a subject, receiving the reflected wave, and imaging or analyzing it.
  • ultrasonic diagnosis a subject can be examined non-destructively and non-invasively.
  • a strain elastography technique for imaging a strain distribution generated by applying pressure to a subject of an object using an ultrasonic probe is known.
  • the hardness of an object can be evaluated from the difference in relative distortion between the object (for example, a tumor) and a reference (for example, fat).
  • JP 2005-13283 A Japanese Patent No. 4981023 Japanese Patent No. 5536300 Japanese Patent No. 5441493
  • the conventional automatic compression mechanism and stabilizer described above lead to an increase in the cost of the ultrasonic probe (ultrasound diagnostic apparatus). Further, the ultrasonic probe is bulky, and it is necessary to attach and detach the ultrasonic probe, which is troublesome.
  • An object of the present invention is to promote uniform pressure on a subject without attaching an additional part to the ultrasonic probe.
  • an ultrasonic diagnostic apparatus comprises: An ultrasonic diagnostic apparatus that applies pressure to an object by an ultrasonic probe that transmits and receives ultrasonic waves, transmits and receives ultrasonic waves to the object of the object, and measures distortion of the object, A transmitter for supplying a drive signal to the ultrasonic probe; A reception unit for processing a reception signal output from the ultrasonic probe; A strain information calculation unit that calculates strain information as elasticity information of the subject generated by the compression based on the processed received signal; A strain balance calculating unit that calculates a horizontal strain distribution of the subject from the strain information calculated by the strain information calculating unit, and calculates a balance of the horizontal strain distribution from the horizontal strain distribution; A distortion information generation unit that generates balance display information indicating a balance of the distortion distribution in the horizontal direction.
  • the invention according to claim 2 is the ultrasonic diagnostic apparatus according to claim 1,
  • the strain information calculation unit is an elastic image generation unit that generates elastic image data indicating a two-dimensional strain distribution based on the processed reception signal.
  • the strain balance calculation unit calculates a balance of strain distribution in the horizontal direction from the generated elasticity image data.
  • the invention according to claim 3 is the ultrasonic diagnostic apparatus according to claim 2,
  • the strain balance calculation unit calculates a balance of strain distribution in the horizontal direction using an elastic image on the body surface side from a predetermined vertical position in the generated elastic image data.
  • the invention according to claim 4 is the ultrasonic diagnostic apparatus according to claim 2 or 3,
  • the distortion information generation unit generates the balance display information including a regression line indicating the balance of the calculated horizontal distortion distribution and a reference display element indicating an allowable range of inclination of the regression line.
  • the invention according to claim 5 is the ultrasonic diagnostic apparatus according to claim 4,
  • the distortion information generation unit changes a color of the regression line according to an evaluation result of an allowable range of the slope of the regression line with respect to the reference display element.
  • the invention according to claim 6 is the ultrasonic diagnostic apparatus according to claim 1,
  • the strain information calculation unit is an elastic image generation unit that generates elastic image data indicating a two-dimensional strain distribution based on the processed reception signal.
  • the strain balance calculation unit calculates a two-dimensional strain cumulative distribution indicating a cumulative amount of strain in the vertical direction from the generated elasticity image data,
  • the strain information generation unit generates a two-dimensional isoline distribution from the two-dimensional strain cumulative distribution.
  • the invention according to claim 7 is the ultrasonic diagnostic apparatus according to claim 6,
  • the distortion information generation unit determines a color of a line of the two-dimensional isoline distribution from the shape of the line.
  • the invention according to claim 8 is the ultrasonic diagnostic apparatus according to claim 6,
  • the distortion information generation unit generates only the isoline on the superficial side in the two-dimensional isoline distribution.
  • the invention according to claim 9 is the ultrasonic diagnostic apparatus according to any one of claims 1 to 8,
  • generated balance display information on a display part is provided.
  • the invention according to claim 10 is the ultrasonic diagnostic apparatus according to claim 9,
  • the display control unit increases the amount of display information in the cine mode than in the live mode.
  • the invention according to claim 11 is the ultrasonic diagnostic apparatus according to any one of claims 1 to 10,
  • Display information to be displayed together with the balance display information includes a balance score of the horizontal distortion distribution, a distortion amount, a reliability value based on the received signal, and the horizontal direction of at least one frame before and after the current frame. It includes at least one of the balance lines of the strain distribution.
  • the invention according to claim 12 An ultrasonic information processing method for applying pressure to an object by an ultrasonic probe that transmits and receives ultrasonic waves and transmitting and receiving ultrasonic waves to the object of the object and measuring distortion of the object, Supplying a driving signal to the ultrasonic probe; Processing the received signal output from the ultrasound probe; Calculating strain information as elasticity information of the subject caused by the compression based on the processed received signal; Calculating a horizontal strain distribution of the subject from the calculated strain information, and calculating a balance of the horizontal strain distribution from the horizontal strain distribution; Generating balance display information indicating the balance of the horizontal strain distribution.
  • 1 is an external view of an ultrasonic diagnostic apparatus according to a first embodiment of the present invention. It is a block diagram which shows the function structure of the ultrasound diagnosing device of 1st Embodiment. It is a figure which shows an elasticity image. It is a figure which shows the regression line of the strain distribution of an elastic image, and strain distribution. It is a figure which shows the 1st distortion balance display column with uniform distortion distribution. It is a figure which shows the 1st distortion balance display column with nonuniform distortion distribution. It is a figure which shows an elastic image and a boundary line. It is a block diagram which shows the function structure of the ultrasonic diagnosing device of 2nd Embodiment. It is a figure which shows the 1st distortion balance display column in live mode.
  • FIG. 1 is an external view of an ultrasonic diagnostic apparatus 100 according to the present embodiment.
  • FIG. 2 is a block diagram showing a functional configuration of the ultrasonic diagnostic apparatus 100.
  • the ultrasonic diagnostic apparatus 100 is an apparatus that displays and outputs an ultrasonic image of a state of a living body tissue of a subject such as a living body of a patient. That is, the ultrasonic diagnostic apparatus 100 transmits ultrasonic waves (transmission ultrasonic waves) to the inside of a subject such as a living body, and transmits reflected ultrasonic waves (reflected ultrasonic waves: echoes) reflected within the subject. Receive. The ultrasound diagnostic apparatus 100 converts the received reflected ultrasound into an electrical signal, and generates ultrasound image data based on this. The ultrasonic diagnostic apparatus 100 displays the internal state in the subject as an ultrasonic image based on the generated ultrasonic image data. Further, the ultrasonic diagnostic apparatus 100 has a strain elastography function and displays an elastic image showing a strain distribution inside the subject to which compression is applied.
  • the ultrasonic diagnostic apparatus 100 includes an ultrasonic diagnostic apparatus main body 1 having an operation input unit 11 and a display unit 20, an ultrasonic probe 2, and a cable 3.
  • the ultrasonic probe 2 transmits transmission ultrasonic waves to the inside of the subject and receives reflected ultrasonic waves from the inside of the subject.
  • the ultrasonic diagnostic apparatus main body 1 is connected to the ultrasonic probe 2 via the cable 3, and transmits an electric signal drive signal to the ultrasonic probe 2 so that the ultrasonic probe 2 is connected to the inside of the subject.
  • the ultrasonic diagnostic apparatus main body 1 also receives a reception signal that is an electrical signal generated by the ultrasonic probe 2 in response to the reflected ultrasonic wave from the subject received by the ultrasonic probe 2. Then, ultrasonic image data is generated and displayed using the received signal.
  • the ultrasonic probe 2 includes a transducer 2a (see FIG. 2) made of a piezoelectric element.
  • a transducer 2a made of a piezoelectric element.
  • a plurality of the transducers 2a are arranged in a one-dimensional array in the azimuth direction (scanning direction).
  • the ultrasonic probe 2 including 192 transducers 2a is used.
  • the vibrators 2a may be arranged in a two-dimensional array.
  • the number of vibrators 2a can be set arbitrarily.
  • a linear electronic scanning probe is used as the ultrasonic probe 2 to perform ultrasonic scanning by the linear scanning method.
  • either the sector scanning method or the convex scanning method is used. It can also be adopted.
  • Communication between the ultrasonic diagnostic apparatus main body 1 and the ultrasonic probe 2 may be performed by wireless communication such as UWB (Ultra Wide Band) instead of wired communication via the cable 3.
  • UWB Ultra Wide Band
  • the ultrasonic diagnostic apparatus main body 1 includes, for example, an operation input unit 11, a transmission unit 12, a reception unit 13, a B-mode image generation unit 14, a storage unit 14a, and a distortion information calculation unit.
  • an elastic image generation unit 15 a storage unit 15a, an elastic image synthesis unit 16, a strain balance calculation unit 17, a strain information generation unit 18, a display image generation unit 19 as a display control unit, and a display unit 20 And a control unit 21.
  • the operation input unit 11 includes, for example, various switches, buttons, a trackball, a mouse, and a keyboard for an inspector such as a doctor or an engineer to input data such as a command for instructing the start of examination or personal information of the subject. Etc., and outputs an operation signal to the control unit 21.
  • the transmission unit 12 is a circuit that supplies a drive signal, which is an electrical signal, to the ultrasonic probe 2 via the cable 3 according to the control of the control unit 21 and causes the ultrasonic probe 2 to generate transmission ultrasonic waves.
  • the transmission unit 12 includes, for example, a clock generation circuit, a delay circuit, a time and voltage setting unit, and a pulse generation circuit.
  • the clock generation circuit is a circuit that generates a clock signal that determines the transmission timing and transmission frequency of the drive signal.
  • the delay circuit sets a delay time for each individual path corresponding to each transducer corresponding to the transmission timing of the drive signal, delays the transmission of the drive signal by the set delay time, and transmits the transmission beam constituted by the transmission ultrasonic waves. This is a circuit for focusing.
  • the time and voltage setting unit is a circuit that sets the voltage of the pulse width of the pulse signal generated from the pulse generation circuit and the voltage of the amplitude.
  • the pulse generation circuit is a circuit for generating a pulse signal as a drive signal in accordance with the time and voltage set by the time and voltage setting unit.
  • the transmitter 12 configured as described above drives, for example, a continuous part (for example, 64) of a plurality (for example, 192) of the transducers 2a arranged in the ultrasound probe 2. Then, transmit ultrasonic waves are generated. Then, the transmission unit 12 performs scanning (scanning) by shifting the driven vibrator in the azimuth direction each time transmission ultrasonic waves are generated.
  • the receiving unit 13 is a circuit that receives a reception signal, which is an electrical signal, from the ultrasound probe 2 via the cable 3 under the control of the control unit 21 and generates sound ray data by performing signal processing on the reception signal. .
  • the receiving unit 13 includes, for example, an amplifier, an A / D conversion circuit, and a phasing addition circuit.
  • the amplifier is a circuit for amplifying a received signal with a preset amplification factor for each individual path corresponding to each transducer.
  • the A / D conversion circuit is a circuit for A / D converting the amplified received signal.
  • the phasing addition circuit adjusts the time phase by giving a delay time to each individual path corresponding to each transducer with respect to the A / D converted received signal, and adds these (phasing addition) to generate a sound ray. It is a circuit for generating data.
  • the B-mode image generation unit 14 Under the control of the control unit 21, the B-mode image generation unit 14 performs envelope detection processing, logarithmic amplification, and the like on the sound ray data from the reception unit 13, and adjusts the dynamic range and gain to perform luminance conversion.
  • B (Brightness) mode ultrasonic image data (B-mode image data) is generated as tomographic image data.
  • the B-mode image data represents the intensity of the received signal by luminance.
  • the storage unit 14a is a storage unit configured by a semiconductor memory such as DRAM (Dynamic Random Access Memory).
  • the B mode image generation unit 14 stores the generated B mode image data in the storage unit 14a in units of frames.
  • the B-mode image generation unit 14 appropriately reads out the B-mode image data stored in the storage unit 14 a and outputs it to the elastic image synthesis unit 16.
  • the elastic image generation unit 15 performs a calculation on the sound ray data from the reception unit 13 according to the control of the control unit 21, has a distortion information calculation function for calculating information as elasticity information, and performs color mapping. Thus, elastic image data is generated.
  • the size of the image of the elasticity image data generated by the elasticity image generation unit 15 is the size of the ROI (Region Of : Interest: region of interest) designated and input by the examiner via the operation input unit 11. It is not limited, and it may be the same as the image size of the B-mode image data.
  • the storage unit 15a is a storage unit configured by a semiconductor memory such as a DRAM.
  • the examiner grasps the ultrasonic probe 2 and applies pressure to the body surface of the subject.
  • the force applied to the subject from the ultrasonic probe 2 changes due to the vibration of the examiner himself or the breathing of the subject.
  • the upper end of an object such as a tumor is located at a distance xr in the depth direction (X direction) from the body surface in contact with the ultrasound probe 2 in the subject before the pressure is applied.
  • the width of the object in the depth direction is L.
  • the elastic image generation unit 15 appropriately stores and reads the sound ray data from the reception unit 13 in the storage unit 15a for each frame.
  • sound ray data of two frames that are temporally continuous is acquired.
  • the pressurized state of the subject corresponding to the first signal waveform of the sound ray data of the first frame is set as the first pressurized state, and the second signal waveform of the sound ray data of the second frame is handled.
  • the pressurized state of the subject to be performed is the second pressurized state.
  • the elastic image generation unit 15 extracts a phase difference component at each time between the first signal waveform and the second signal waveform, and according to a correlation between each time and the phase difference component at each time. Then, the distortion difference and the initial phase difference relating to the frequency difference between the first signal waveform and the second signal waveform are calculated, and the distortion amount is calculated based on the distortion difference. The elastic image generation unit 15 calculates the distortion amount for all the pixels, and generates image data including the distortion amount pixels.
  • the elastic image generation unit 15 generates elastic image data by coloring the image data of the distortion amount by color mapping in which the distortion amount increases in the order of blue ⁇ green ⁇ yellow ⁇ red, for example.
  • the amount of distortion increases in the order of black ⁇ white in the elastic image.
  • the elastic image synthesis unit 16 synthesizes the B-mode image data generated by the B-mode image generation unit 14 and the elastic image data generated at the same time generated by the elastic image generation unit 15 according to the control of the control unit 21. Elastic image data is generated.
  • the strain balance calculation unit 17 uses the elastic image data generated by the elastic image generation unit 15 in the horizontal direction of the elastic image (scanning direction, direction parallel to the body surface, depth direction (X direction)). A regression line of the distribution of the distortion amount of the pixel in the Y direction (vertical Y direction) (distortion distribution in the horizontal direction) is calculated.
  • FIG. 3A is a diagram showing an elastic image 201.
  • FIG. 3B is a diagram illustrating a strain distribution 202 of the elastic image 201 and a regression line 203 of the strain distribution 202.
  • FIG. 3A shows an elasticity image 201 of elasticity image data generated by the elasticity image generation unit 15.
  • the strain balance calculation unit 17 calculates the sum of strain values for each pixel column in the X direction along the Y direction of the elastic image 201 to calculate a strain distribution 202 as shown in FIG. 3B.
  • the distortion balance calculation part 17 calculates the regression line 203 of the distortion distribution 202 by the least square method etc., for example.
  • the distortion information generation unit 18 generates, as distortion information, a distortion balance display field having a balance line based on the regression line using the regression line of the distortion distribution generated by the distortion balance calculation unit 17 according to the control of the control unit 21. To do.
  • FIG. 4A is a diagram showing a strain balance display field 300 having a uniform strain distribution.
  • FIG. 4B is a diagram showing a strain balance display field 300 in which the strain distribution is not uniform.
  • the distortion balance display field 300 includes a center point 311, a balance line 312, a reference line 313, and a reference region 314.
  • the center point 311 is a mark indicating the center of the strain balance display field 300, and indicates the center of the elastic image 201 in the horizontal direction, for example.
  • the balance line 312 is a straight line that passes through the center point 311 and has the slope of the regression line of the calculated strain distribution.
  • the reference line 313 is a horizontal straight line passing through the center point 311.
  • the reference area 314 is a reference area that indicates an allowable range of inclination of the balance line 312 in order to determine whether or not the balance line 312 is uneven, and has a predetermined width that is set in advance above and below the reference line 313.
  • the balance straight line 312 overlaps the reference line 313, and the strain distribution is uniform.
  • the distortion balance display column 300 in FIG. 4B indicates that the balance line 312 does not overlap the reference line 313 but protrudes from the reference region 314, and the distortion distribution is non-uniform.
  • the tolerance of the inclination of the balance line 312 with respect to the reference area 314 is displayed so that the balance line 312 in the reference area 314 including the uniform distortion distribution is displayed in blue and the balance line 312 having the non-uniform distortion distribution is displayed in red. It is preferable to change the color of the balance line 312 according to the evaluation result of the range.
  • the display image generation unit 19 combines the combined elasticity image data generated by the elasticity image synthesis unit 16 and the strain balance display field generated by the strain information generation unit 18 according to the control of the control unit 21 to display the display image. Data is generated, and the display image data is converted into an image signal for the display unit 20 and output to the display unit 20.
  • the display unit 20 may be a display device such as an LCD (Liquid Crystal Display), a CRT (Cathode-Ray Tube) display, an organic EL (Electronic Luminescence) display, an inorganic EL display, or a plasma display.
  • the display unit 20 displays an image on the display screen according to the image signal output from the display image generation unit 19.
  • the control unit 21 includes, for example, a CPU (Central Processing Unit), a ROM (Read Only Memory), and a RAM (Random Access Memory), and reads various processing programs such as a system program stored in the ROM to read the RAM.
  • the operation of each part of the ultrasonic diagnostic apparatus 100 is centrally controlled according to the developed program.
  • the ROM is configured by a non-volatile memory such as a semiconductor, and stores a system program corresponding to the ultrasonic diagnostic apparatus 100, a program executable on the system program, various data such as a gamma table, and the like. These programs are stored in the form of computer-readable program code, and the CPU sequentially executes operations according to the program code.
  • the RAM forms a work area for temporarily storing various programs executed by the CPU and data related to these programs. In order to prevent the diagram from becoming complicated, some control lines from the control unit 21 to each unit are omitted in FIG.
  • each functional block can be realized as a hardware circuit such as an integrated circuit.
  • the integrated circuit is, for example, an LSI (Large Scale Integration), and the LSI may be referred to as an IC, a system LSI, a super LSI, or an ultra LSI depending on the degree of integration.
  • the method of circuit integration is not limited to LSI, but may be realized by a dedicated circuit or a general-purpose processor, and the connection and setting of FPGA (Field Programmable Gate Array) and circuit cells inside LSI can be reconfigured.
  • a reconfigurable processor may be used.
  • some or all of the functions of each function block may be executed by software.
  • the software is stored in one or more storage media such as a ROM, an optical disk, or a hard disk, and the software is executed by the arithmetic processor.
  • the ultrasonic probe 2 is first contacted with the subject, B-mode image data is generated, and a B-mode image is displayed.
  • the elastic image ROI is appropriately input via the operation input unit 11 and the ultrasonic probe 2 applies pressure to the body surface around the subject of the subject.
  • ultrasonic transmission / reception from the ultrasonic probe 2 is performed by the transmission unit 12 and the reception unit 13.
  • B-mode image data generation by the B-mode image generation unit 14, elasticity image data generation by the elasticity image generation unit 15, and synthesis elasticity image data generation by the elasticity image synthesis unit 16 are performed.
  • the regression line generation of the horizontal strain distribution by the strain balance calculation unit 17 and the strain balance display column by the strain information generation unit 18 are generated, and the display including the synthetic elasticity image data and the strain balance display column by the display image generation unit 19 is generated.
  • Image data is generated and displayed on the display unit 20.
  • the composite elastic image and the strain balance display column are arranged so that the centers thereof coincide.
  • the inspector can correct the bias of the compression via the ultrasonic probe 2 by visually observing the distortion balance display field on the display image displayed on the display unit 20. More specifically, the inspector may operate the ultrasound probe 2 so that the balance straight line in the distortion balance display field matches the reference line. The examiner can more accurately diagnose the hardness of an object such as a tumor in the synthetic elastic image by visually observing the synthetic elastic image when the balance straight line is aligned with the reference line.
  • the ultrasonic diagnostic apparatus 100 compresses the subject with the ultrasonic probe 2 and transmits / receives ultrasonic waves to / from the subject of the subject to measure the distortion of the subject.
  • the ultrasonic diagnostic apparatus 100 supplies a drive signal to the ultrasonic probe 2, processes a reception signal output from the ultrasonic probe 2, and based on the processed reception signal, a subject generated by compression Calculate strain information to calculate strain information as elasticity information, calculate the horizontal strain distribution of the subject from the calculated strain information, and calculate the balance of the horizontal strain distribution from the horizontal strain distribution
  • a distortion balance display field is generated as balance display information indicating the balance of the distortion distribution in the horizontal direction.
  • the balance line and balance display information generated and displayed here do not simply indicate the pressing direction or angle when the ultrasonic probe 2 is pressed against the body surface of the subject. Since the hardness of the tissue in the subject is reflected in addition to the pressing direction and angle information, it is an index for performing more accurate elastic image display.
  • the examiner is encouraged to apply uniform pressure to the subject so that the strain balance is uniform. it can.
  • the ultrasound diagnostic apparatus 100 generates elastic image data as a two-dimensional strain distribution based on the processed received signal, and a horizontal strain distribution balance (regression line) from the generated elastic image data. Is calculated. For this reason, it is possible to easily calculate the regression line of the strain distribution in the horizontal direction by effectively using the elastic image data to be displayed.
  • the ultrasonic diagnostic apparatus 100 generates a distortion balance display column including a horizontal distortion balance line (regression line) based on the balance and a reference display area indicating an allowable range of the balance line inclination. Therefore, by displaying the distortion balance display field, the horizontal distortion balance line can be easily visually recognized by the horizontal distortion balance line, and the balance of the compression to the subject can be balanced by the balance straight line with respect to the reference display area. The inspector can easily visually check whether the tolerance is acceptable.
  • the ultrasound diagnostic apparatus 100 changes the color of the balance line according to the evaluation result of the allowable range of the balance line inclination with respect to the reference display area. For this reason, by displaying the distortion balance display field, the examiner can easily visually recognize whether the balance of the pressure on the subject is within the allowable range by the color of the balance line.
  • the ultrasonic diagnostic apparatus 100 displays the generated strain balance display field on the display unit 20. For this reason, it is possible to visually encourage the examiner to uniformly press the subject so as to make the balance of distortion uniform.
  • FIG. 5 is a diagram illustrating the elasticity image 205 and the boundary line 206.
  • the ultrasonic diagnostic apparatus 100 according to the first embodiment is used, and different parts of the operation are mainly described, and description of the same parts is omitted.
  • the pressure applied to the subject is attenuated and reduced as the depth increases, and the amount of distortion also decreases. For this reason, in this modification, in order to generate a strain distribution in the horizontal direction, the strain amount only in the shallow region on the body surface side of the elastic image data is used.
  • the strain balance calculation unit 17 includes an image of a region 205a that is greater than or equal to the boundary line 206 in the Y direction in the elasticity image data of the elasticity image 205 illustrated in FIG. 5 generated by the elasticity image generation unit 15.
  • a distortion distribution in the horizontal direction is generated using the distortion amount of each pixel of the data, and a regression line of the distortion distribution is generated.
  • the position of the boundary line 206 is focused by, for example, a predetermined position such as a middle position in the X direction of the elastic image of the elastic image data, or by an inspector's position input via the operation input unit 11 before scanning.
  • the user-set position or the like such as the set position.
  • the focus position is a position where the sound pressure of the ultrasonic wave is highest.
  • the ultrasound diagnostic apparatus 100 uses the elastic image data on the body surface side that is greater than or equal to the horizontal boundary line among the generated elastic image data, and the regression line of the strain distribution in the horizontal direction. Is calculated. For this reason, it is possible to improve the sensitivity of the horizontal distortion balance line based on the regression line.
  • FIG. 6 is a block diagram showing a functional configuration of the ultrasonic diagnostic apparatus 100A of the present embodiment.
  • ultrasonic diagnostic apparatus 100A of the present embodiment parts that are different from the ultrasonic diagnostic apparatus 100 of the first embodiment will be mainly described, and the same reference numerals are given to the same parts, and the description thereof will be omitted.
  • the ultrasonic diagnostic apparatus 100A includes an ultrasonic diagnostic apparatus main body 1A, an ultrasonic probe 2, and a cable 3.
  • the ultrasonic diagnostic apparatus main body 1A includes, for example, an operation input unit 11, a transmission unit 12, a reception unit 13, a B-mode image generation unit 14, a storage unit 14a, an elastic image generation unit 15, and a storage unit 15a.
  • An elastic image composition unit 16, a strain balance calculation unit 17, a strain information generation unit 18A as a display information generation unit, a display image generation unit 19A, a storage unit 19a, a display unit 20, a control unit 21, A distortion amount calculation unit 22 and a state management unit 23 are provided.
  • the distortion amount calculation unit 22 calculates the total amount of pixel distortion amount distribution (horizontal strain distribution) in the horizontal direction (Y direction) from the elastic image data generated by the elastic image generation unit 15. calculate.
  • the state management unit 23 is a live mode in which ultrasonic image data obtained by scanning the subject is displayed in real time in accordance with an operation input from the examiner via the operation input unit 11 according to the control of the control unit 21 or in the past. It manages state information as to whether it is a cine mode for displaying (reproducing) ultrasonic image data (cine) stored in the live mode, and outputs the state information to the distortion information generation unit 18A.
  • scanned ultrasonic image data synthetic elastic image data
  • the distortion information generation unit 18A uses the regression line of the distortion distribution generated by the distortion balance calculation unit 17, and sets the horizontal as a predetermined perfect score (for example, 100 points), so that the inclination of the regression line is large.
  • the score at which the percentage of deductions becomes larger is calculated, a distortion balance display field having a balance line based on the regression line is generated, the distortion amount of the center point input from the distortion amount calculation unit 22, and the score and distortion balance display
  • the column and the distortion information are output to the display image generation unit 19A together with the state information input from the state management unit 23.
  • the display image generation unit 19A and the composite elasticity image data generated by the elasticity image synthesis unit 16 and the strain information are displayed.
  • the distortion balance display field generated by the generation unit 18 is synthesized to generate display image data, and the display image data is converted into an image signal for the display unit 20 and output to the display unit 20 for live image display
  • the composite elastic image data, the strain balance display column, the score, and the strain amount are stored as cine image data in the storage unit 19a for each frame.
  • the storage unit 19a is a nonvolatile memory capable of writing and reading information, such as a flash memory.
  • the display image generation unit 19A responds to the frame designation input of the cine image (synthetic elastic image data) to be reproduced via the operation input unit 11 when the state information input from the distortion information generation unit 18A is the cine mode. Then, the cine image data (synthetic elastic image data, strain balance display column, score and strain amount) of the target frame is read from the storage unit 19a, and has the read elastic image data, strain balance display column, score and strain amount. Display image data is generated, converted into an image signal, and output to the display unit 20 to display a cine image.
  • the B-mode image generation unit 14 stores B-mode image data as cine image data in the storage unit 14a
  • the elastic image generation unit 15 stores elastic image data as cine image data in the storage unit 15a.
  • the B-mode image generation unit 14 reads out the B-mode image data of the frame designated by the examiner via the operation input unit 11 from the storage unit 14a, and the elastic image generation unit 15 is designated.
  • the elastic image data of the frame is read from the storage unit 15a, and the elastic image synthesis unit 16 synthesizes the read B-mode image data and the elastic image data to output the synthesized elastic image data to the display image generation unit 19,
  • the display image generation unit 19A reads the strain balance display column, the score, and the distortion amount of the designated frame from the storage unit 19a and displays them on the display unit 20 together with the input synthetic elastic image data.
  • FIG. 7A is a diagram showing a distortion balance display field 300 in the live mode.
  • FIG. 7B is a diagram showing a distortion balance display field 300A in the cine mode.
  • the distortion balance display field 300 in the live mode is displayed as a balance display field similar to FIGS. 4A and 4B.
  • the distortion balance display column 300A in the cine mode includes a center point 311, a balance line 312, a reference line 313, a reference region 314, a score 315, and a total distortion amount 316.
  • the score 315 is a score based on the score calculated by the distortion information generation unit 18 ⁇ / b> A, with the slope at which the balance line 312 matches the reference line 313 being a perfect score.
  • the total distortion amount 316 is the total amount of distortion calculated by the distortion amount calculation unit 22.
  • the ultrasonic diagnostic apparatus 100A increases the amount of display information in the cine mode than in the live mode. For this reason, display flicker in the distortion balance display field can be reduced in the live mode in which the display information amount is suppressed, and in the cine mode in which the display information amount is large, the examiner can assist the selection of each frame used for diagnosis. .
  • the ultrasonic diagnostic apparatus 100A displays a horizontal distribution score of distortion as distortion information. For this reason, the examiner can quantitatively confirm the uniformity of the pressure on the subject.
  • the ultrasonic diagnostic apparatus 100A generates and displays the total amount of distortion as distortion information to be displayed together with the distortion balance display field. For this reason, the examiner can simultaneously confirm the uniformity of compression and the amount of compression.
  • FIG. 8 is a diagram showing a distortion balance display field 300B.
  • the ultrasonic diagnostic apparatus 100A according to the second embodiment is used, and mainly the parts with different operations are described, and the description of the same parts is omitted.
  • the display image generation unit 19A When the state information input from the distortion information generation unit 18A is in the cine mode, the display image generation unit 19A responds to the designation input of the frame of the cine image (synthetic elastic image data) to be reproduced via the operation input unit 11,
  • the cine image data synthetic elastic image data, strain balance display column, score and distortion amount
  • the read elasticity Display image data having image data, a distortion balance display field, a score, and a distortion amount is generated and output to the display unit 20 to display a cine image.
  • the distortion balance display column displayed in the cine mode will be described.
  • the distortion balance display field 300B in the cine mode includes a center point 311, a balance line 312, a reference line 313, a reference area 314, a score 315, a total distortion amount 316, a balance line 317, 318.
  • the balance straight line 312 is a balance straight line corresponding to the current frame of the composite elastic image displayed at the same time, and is displayed, for example, as a solid thick line.
  • the balance straight line 317 is a balance straight line corresponding to the frame one frame before the composite elastic image to be displayed, and is displayed, for example, as a thin line with a one-dot chain line.
  • the balance straight line 318 is a balance straight line corresponding to a frame one frame after the composite elastic image to be displayed, and is displayed as a thin dotted line, for example.
  • the distortion distribution is non-uniform, and therefore, for example, the balance straight lines 312, 317, and 318 are displayed in red different from blue where the distortion distribution is uniform.
  • the balance straight line in the distortion balance display column displayed in the cine mode is not limited to three corresponding to the current frame and the frames before and after the current frame, but at least one of the current frame and at least one before and after this. It is good also as at least 1 corresponding to a flame
  • the distortion balance display field displayed in the live mode also displays at least one balance line at least one frame in addition to the balance line of the current frame corresponding to the currently displayed composite elastic image. Also good.
  • the ultrasonic diagnostic apparatus 100A generates and displays a balance line of at least one frame before and after the current frame as distortion information to be displayed together with the distortion balance display field. For this reason, the continuity of uniform compression can be confirmed by visual recognition of the strain balance display column and the balance straight lines of the front and rear frames.
  • FIG. 9A is a diagram showing a distortion balance display field 300C when the amount of distortion is small.
  • FIG. 9B is a diagram showing a distortion balance display field 300C when the amount of distortion is large.
  • the ultrasonic diagnostic apparatus 100A according to the second embodiment is used, and mainly the parts with different operations are described, and the description of the same parts is omitted.
  • the distortion information generation unit 18A uses the regression line of the distortion distribution generated by the distortion balance calculation unit 17 and sets the horizontal as a predetermined perfect score, and the percentage of deduction points increases as the regression line increases in inclination.
  • a score to be increased is calculated, and a distortion balance display field including a total distortion amount input from the distortion amount calculation unit 22 and a balance line based on the regression line is generated, and the score and the distortion balance display field are used as distortion information.
  • the information is output to the display image generation unit 19A.
  • a distortion balance display field 300C shown in FIGS. 9A and 9B is generated.
  • the distortion balance display field 300C includes a balance line 312, a reference line 313, a reference region 314, and a center circle 319.
  • the center circle 319 is a circular mark indicating the center of the strain balance display field 300C.
  • the center circle 319 indicates the center in the Y direction of the elastic image and has a radius (diameter) corresponding to the total strain amount input from the strain amount calculation unit 22. ).
  • the balance straight line 312 and the reference line 313 are arranged so as to pass through the center of the central circle 319.
  • the distortion balance display column 300C is information displayed in both the live mode and the cine mode.
  • the ultrasound diagnostic apparatus 100A generates and displays a center circle indicating the total strain amount in the strain balance display field as the strain information to be displayed together with the strain balance display field. Therefore, the visual inspection of the strain balance display field and the central circle indicating the total amount of distortion allows the examiner to easily achieve uniform compression on the subject, and the visual inspection of the central circle indicating the total amount of distortion allows the examiner to Can easily confirm whether or not there is appropriate pressure on the subject. Moreover, it is good also as a structure which displays a standard
  • FIG. 10A is a diagram illustrating a signal waveform of sound ray data of two consecutive frames.
  • FIG. 10B is a diagram showing a distortion balance display field 300D.
  • the ultrasonic diagnostic apparatus 100A according to the second embodiment is used, and mainly the parts with different operations are described, and the description of the same parts is omitted.
  • the elastic image generation unit 15 generates elastic image data using time-sequential two frames of sound ray data from the reception unit 13 and the storage unit 15a according to the control of the control unit 21, and the elastic image data time
  • the correlation value (restoration rate) of the signal waveform is calculated using the sound ray data of two consecutive frames, and the calculated correlation value is used as the reliability value of the measurement result, and the distortion information generation unit is connected via the distortion balance calculation unit 17. Output to 18A.
  • the signal waveform f (x) of the sound ray data of the first frame the signal waveform g (x) of the sound ray data of the second frame temporally next to the first frame,
  • the correlation value AutoCorr (f (x), g (x + ⁇ x)) is calculated.
  • the strain information generation unit 18A calculates a score using the regression line of the strain balance generated by the strain balance calculation unit 17 according to the control of the control unit 21, and trusts the elasticity image input from the strain balance calculation unit 17.
  • a distortion balance display field having a value and the regression line is generated, and the score and the total distortion amount input from the distortion amount calculation unit 22 are used as distortion information, along with the state information input from the state management unit 23, The image is output to the display image generation unit 19A.
  • a distortion balance display field 300D shown in FIG. 10B is generated.
  • the distortion balance display field 300D includes a balance line 312, a reference line 313, a reference region 314, and a center circle 320.
  • the center circle 320 is a circular mark indicating the center of the strain balance display field 300D.
  • the center circle 320 indicates the center of the elastic image in the Y direction, and the reliability value of the elastic image of the elastic image data calculated by the elastic image generating unit 15.
  • the confidence value is high ( ⁇ 1) when no pressure is applied to the subject, and the confidence value decreases as the pressure increases, and the confidence value decreases and the correlation disappears when the pressure is excessive. For this reason, it is preferable to confirm appropriate compression according to reliability.
  • the ultrasonic diagnostic apparatus 100A displays the center circle indicating the reliability value of the ROI distortion in the distortion balance display column as the distortion information. For this reason, it is possible for the examiner to easily realize uniform compression on the subject by visualizing the strain balance display field, and for the examiner to appropriately compress the subject on the subject by visualizing the central circle indicating the reliability value. It can be easily confirmed whether or not there is. Moreover, it is good also as a structure which displays standard
  • FIG. 11 is a diagram showing an elasticity image 330 and an isoline 331.
  • FIG. 12 is a diagram showing a B-mode image 340 on which isolines 331 are superimposed.
  • the ultrasonic diagnostic apparatus 100 according to the first embodiment is used, and different parts of the operation are mainly described, and description of the same parts is omitted.
  • the regression line of the strain distribution in the Y direction (horizontal direction) as the balance line in the first embodiment generally indicates that the slope is pressed if the inside of the scan portion of the subject is uniform.
  • the right side of the medium is harder than the left side, even if the right side is pushed in, distortion does not occur, and an inclination indicating the pressing cannot be obtained.
  • a horizontal isoline of the cumulative distribution of strain values in the X direction (vertical direction) is displayed as balance display information.
  • the isoline is a line in which the accumulated strain value becomes equal from the shallow part of the subject, and is a display element that is an image of a pressing isobaric line. If the contour line is dense, it indicates that there is a lot of distortion (the pressure is strong or the medium is soft).
  • the strain balance calculation unit 17 uses the strain amount of each pixel of the elasticity image data of the elasticity image 330 illustrated in FIG. 11 generated by the elasticity image generation unit 15 to use the strain distribution in the Y direction. And a two-dimensional strain cumulative distribution indicating a Y-direction distribution of the cumulative amount of strain in the X direction.
  • the distortion information generation unit 18 generates a distortion balance display column including a balance line (regression line) based on the regression line of the distortion distribution in the Y direction generated by the distortion balance calculation unit 17, and the distortion balance calculation unit 17 Image data of a two-dimensional isoline distribution to be superimposed on the B-mode image of the B-mode image data is generated from the generated two-dimensional strain cumulative distribution.
  • the distortion information generation unit 18 may be configured to change the color of each line of the isoline distribution according to the shape of the isoline (for example, the horizontal level of the line). For example, in the isoline 331 shown in FIG. 11, the color of the isoline 331a having a high level of horizontal and the isoline 331b having a low level of horizontal is changed.
  • the isoline 331a is displayed as, for example, a light blue solid line
  • the isoline 331b is displayed as, for example, an orange solid line.
  • the display image generating unit 19 converts the B mode image data generated by the B mode image generating unit 14 (the elastic image data is not combined by the elastic image combining unit 16) into the ROI (elastic image portion) of the B mode image.
  • the strain balance display field and the two-dimensional isoline distribution as the balance display information, for example, the balance straight line is inclined, but the isolines are equidistant in shallow areas, so there is no bias
  • the examiner can determine that the subject is being pushed.
  • it is good also as a structure which displays only two-dimensional isoline distribution as balance display information.
  • the distortion information generation unit 18 displays only the surface side of the isoline (for example, only the isoline 331a). It is good also as a structure which produces
  • the display image generation unit 19 generates display image data by combining the combined elasticity image data generated by the elasticity image combining unit 16 with the image data of the isoline superimposed on the ROI of the combined elasticity image. It is good also as a structure displayed on the part 20.
  • the display image generation unit 19 generates a composite image of the composite elastic image data generated by the elastic image combination unit 16 and B of the B mode image data generated by the B mode image generation unit 14 for the same part of the subject.
  • the mode image and the two-dimensional isoline distribution may be displayed side by side.
  • the elastic image generation unit 15 generates elastic image data indicating a two-dimensional strain distribution based on the reception signal processed by the reception unit 13.
  • the strain balance calculation unit 17 calculates a two-dimensional strain cumulative distribution indicating the cumulative amount of strain in the vertical direction from the generated elasticity image data.
  • the strain information generation unit 18 generates a two-dimensional isoline distribution from the two-dimensional strain cumulative distribution. For this reason, by displaying the isolines, it is possible to indicate the strength of the press according to the density of the isolines and the softness of the medium, and to the subject uniformly so as to make the balance of distortion uniform. The examiner can be urged to press.
  • the distortion information generation unit 18 determines the line color of the two-dimensional isoline distribution from the shape of the line. For this reason, the inspector can easily visually recognize the degree of horizontality based on the shape of each line of the two-dimensional contour distribution from the color.
  • the distortion information generation unit 18 generates only the superficial side isoline in the two-dimensional isoline distribution. For this reason, it is possible to improve the visibility of the B-mode image or the composite elastic image on which the two-dimensional isoline distribution is superimposed.
  • the distortion balance display field as balance display information is displayed on the display unit 20, but the present invention is not limited to this.
  • An LED Light ⁇ Emitting (Diode) as a display unit provided in a diagnostic apparatus (for example, the ultrasound probe 2) may be turned on, blinked, changed in lighting color, or the like.
  • the sum of the distortion amounts of the pixels in each vertical line in the horizontal direction (azimuth direction) of the elastic image data is calculated to calculate the horizontal distortion distribution.
  • the horizontal distortion distribution may be calculated by calculating a median value, an average value, and the like of the distortion of the pixels of each vertical line in the horizontal direction of the elastic image data.
  • the ultrasonic diagnostic apparatus and ultrasonic information processing method of the present invention can be applied to ultrasonic diagnosis using elastic images.

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Abstract

La présente invention concerne un dispositif de diagnostic par ultrasons (100) qui applique une pression à un sujet, transmet/reçoit des ondes ultrasonores vers/depuis une cible sur le sujet, et mesure la distorsion de la cible au moyen d'une sonde à ultrasons (2) qui transmet et reçoit des ondes ultrasonores. Le dispositif de diagnostic par ultrasons (100) comprend : une unité de transmission (12) qui fournit des signaux de commande à la sonde à ultrasons (2) ; une unité de réception (13) qui traite les signaux reçus transmis par la sonde à ultrasons (2) ; une unité de génération d'image d'élasticité (15) qui, sur la base des signaux reçus traités, calcule sous forme d'informations d'élasticité pour le sujet, des informations de distorsion générées par un moyen de pression ; une unité de calcul d'équilibre de distorsion (17) calcule la distorsion horizontale du sujet à partir des informations de distorsion calculées par l'unité de génération d'image d'élasticité (15) et calcule l'équilibre d'une distribution de distorsion horizontale à partir de la distorsion horizontale ; et une unité de génération d'informations de distorsion (18) qui génère des informations d'affichage d'équilibre qui montrent l'équilibre de la distribution de distorsion horizontale.
PCT/JP2017/007055 2016-02-29 2017-02-24 Dispositif de diagnostic par ultrasons et procédé de traitement d'informations ultrasonores WO2017150368A1 (fr)

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Citations (5)

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WO2005120358A1 (fr) * 2004-06-09 2005-12-22 Hitachi Medical Corporation Procédé d’affichage d’image élastique et dispositif ultrasonographique
WO2005122907A1 (fr) * 2004-06-22 2005-12-29 Hitachi Medical Corporation Ultrasonographe et méthode d’affiche d’image d’élasticité
WO2006040967A1 (fr) * 2004-10-08 2006-04-20 Hitachi Medical Corporation Dispositif de diagnostic ultrasonore
WO2009104657A1 (fr) * 2008-02-21 2009-08-27 株式会社 日立メディコ Dispositif ultrasonographique, procédé de traitement d'image par ultrasons et programme de traitement d'image par ultrasons
JP2010246909A (ja) * 2009-04-10 2010-11-04 Medison Co Ltd 圧力情報を提供する超音波システムおよび方法

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JP3991282B2 (ja) * 2004-08-05 2007-10-17 株式会社日立メディコ 弾性像表示方法及び超音波診断装置
US20080033295A1 (en) * 2004-10-12 2008-02-07 Takeshi Matsumura Ultrasonic Probe and Ultrasonic Imaging Device
WO2012043200A1 (fr) * 2010-09-29 2012-04-05 株式会社 日立メディコ Dispositif de diagnostic par ultrasons, procédé d'affichage d'image ultrasonore et programme

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Publication number Priority date Publication date Assignee Title
WO2005120358A1 (fr) * 2004-06-09 2005-12-22 Hitachi Medical Corporation Procédé d’affichage d’image élastique et dispositif ultrasonographique
WO2005122907A1 (fr) * 2004-06-22 2005-12-29 Hitachi Medical Corporation Ultrasonographe et méthode d’affiche d’image d’élasticité
WO2006040967A1 (fr) * 2004-10-08 2006-04-20 Hitachi Medical Corporation Dispositif de diagnostic ultrasonore
WO2009104657A1 (fr) * 2008-02-21 2009-08-27 株式会社 日立メディコ Dispositif ultrasonographique, procédé de traitement d'image par ultrasons et programme de traitement d'image par ultrasons
JP2010246909A (ja) * 2009-04-10 2010-11-04 Medison Co Ltd 圧力情報を提供する超音波システムおよび方法

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