WO2017140116A1 - Dispositif auxiliaire destiné à surveiller de manière non invasive le taux de glycémie - Google Patents
Dispositif auxiliaire destiné à surveiller de manière non invasive le taux de glycémie Download PDFInfo
- Publication number
- WO2017140116A1 WO2017140116A1 PCT/CN2016/103044 CN2016103044W WO2017140116A1 WO 2017140116 A1 WO2017140116 A1 WO 2017140116A1 CN 2016103044 W CN2016103044 W CN 2016103044W WO 2017140116 A1 WO2017140116 A1 WO 2017140116A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- receiving
- transmitting
- control line
- blood glucose
- glucose concentration
- Prior art date
Links
- 239000008280 blood Substances 0.000 title claims abstract description 84
- 210000004369 blood Anatomy 0.000 title claims abstract description 84
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims abstract description 39
- 239000008103 glucose Substances 0.000 title claims abstract description 39
- 210000003205 muscle Anatomy 0.000 claims abstract description 39
- 238000010521 absorption reaction Methods 0.000 claims description 6
- 238000002835 absorbance Methods 0.000 claims description 4
- 210000001519 tissue Anatomy 0.000 abstract description 24
- 230000005540 biological transmission Effects 0.000 abstract description 4
- 238000000034 method Methods 0.000 description 7
- 206010012601 diabetes mellitus Diseases 0.000 description 5
- 238000001514 detection method Methods 0.000 description 4
- 238000005259 measurement Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 201000001421 hyperglycemia Diseases 0.000 description 3
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- IYZWUWBAFUBNCH-UHFFFAOYSA-N 2,6-dichlorobiphenyl Chemical compound ClC1=CC=CC(Cl)=C1C1=CC=CC=C1 IYZWUWBAFUBNCH-UHFFFAOYSA-N 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 241000282376 Panthera tigris Species 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 230000009693 chronic damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000004064 dysfunction Effects 0.000 description 1
- 210000000624 ear auricle Anatomy 0.000 description 1
- 230000005611 electricity Effects 0.000 description 1
- 210000001508 eye Anatomy 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 210000002216 heart Anatomy 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 230000003914 insulin secretion Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- 210000003802 sputum Anatomy 0.000 description 1
- 208000024794 sputum Diseases 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
- G01N21/3577—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
Definitions
- the present invention relates to the technical field of life health, and in particular, to a non-invasive blood glucose concentration detecting auxiliary device.
- Diabetes is a group of metabolic diseases characterized by hyperglycemia.
- Hyperglycemia is caused by defects in insulin secretion or its biological effects, or both.
- Hyperglycemia which is persistent in people with diabetes, causes chronic damage and dysfunction in various tissues, especially the eyes, kidneys, heart, blood vessels, and nerves.
- a more effective way to control the treatment of diabetes is to strictly control the blood glucose concentration by frequently detecting blood sugar levels and injecting insulin, thereby suppressing complications caused by diabetes and alleviating the suffering of diabetic patients. Therefore, it is very important to regularly check the blood glucose level of patients.
- a primary object of the present invention is to provide a non-invasive blood glucose concentration detecting auxiliary device, which aims to solve the problem of user's monitoring of blood sugar in a non-invasive state.
- the present invention provides a non-invasive blood glucose concentration detecting auxiliary device comprising a control line, a transmitting portion, a spring, a rotating shaft, a receiving portion and a controller, wherein:
- the control line includes a transmission control line and a reception control line;
- the transmitting portion includes a transmitting clip, a launching clip cover and a transmitting triode, and the transmitting clip cover covers the transmitting clip;
- the receiving portion includes a receiving clip, a receiving clip cover and a receiving transistor, and the receiving clip cover covers the receiving clip;
- the launching clip and the receiving clip are connected by the rotating shaft;
- the spring is disposed between the launching clamp and the receiving clamp;
- the controller sends a signal through the emission control line to control the emission of the infrared light emitted by the emission transistor in the muscle tissue of the user, and the infrared light transmitted from the blood of the muscle tissue according to the receiving transistor
- the ratio of the infrared light emitted by the emission transistor calculates the absorption rate of the blood of the muscle tissue, and the blood sugar content in the blood of the muscle tissue of the user is obtained according to the absorbance of the blood of the muscle tissue.
- the transmitting portion further includes an emitting PCB board disposed between the transmitting clip and the launching clip cover.
- the emission PCB is provided with the emission transistor, and the emission transistor is vertically disposed on the emission PCB.
- one end of the emission control line is connected to the emission PCB, and the other end of the emission control line is connected to the controller.
- the receiving portion further comprises a receiving PCB board, and the receiving PCB board is disposed between the receiving clip seat and the receiving clip cover.
- the receiving transistor is disposed on the receiving PCB.
- one end of the receiving control line is connected to the receiving PCB, and the other end of the receiving control line is connected to the controller.
- the emitting portion further includes a rubber sleeve, and the rubber sleeve is disposed on the launching clip cover.
- the shape of the spring is a U-shaped constriction.
- the non-invasive blood glucose concentration detecting auxiliary device of the invention has a simple structure and is convenient to use.
- the device can clamp the muscle or tissue of the user through the spring, the launching clamp and the receiving clamp, and is convenient to use.
- the controller processes the blood glucose, and finally obtains the blood sugar level in the blood of the user's muscle or tissue, and assists in determining the current blood sugar level of the user.
- FIG. 1 is a schematic plan view showing a preferred embodiment of the non-invasive blood glucose concentration detecting auxiliary device of the present invention
- FIG. 2 is a side view showing the structure of a casing of the non-invasive blood glucose concentration detecting auxiliary device of the present invention.
- FIG. 1 is a schematic plan view showing a preferred embodiment of the non-invasive blood glucose concentration detecting assisting device of the present invention
- FIG. 2 is a schematic side view showing the housing of the non-invasive blood glucose concentration detecting assisting device of the present invention.
- the non-invasive blood glucose concentration detecting auxiliary device includes a control line, a transmitting portion, and a spring 4
- the control line includes a transmission control line 1 and a reception control line 13;
- the transmitting portion includes a transmitting clip 2, a launching clip cover 3 and a transmitting triode 8, and the transmitting clip cover 3 is covered on the launching clip 2;
- the receiving portion includes a receiving clip 11, a receiving clip cover 12 and a receiving transistor 9, and the receiving clip cover 12 is covered on the receiving clip 11;
- the launching clamp 2 and the receiving clamp 11 are connected by the rotating shaft 5, [0033] the spring 4 is disposed between the launching clamp 2 and the receiving clamp 11;
- the controller 14 sends a signal through the emission control line 1 to control the emission transistor 8 to emit infrared light to illuminate the muscle tissue blood of the user, and transmits the blood from the muscle tissue according to the receiving transistor 9.
- the ratio of the infrared light to the infrared light emitted from the emitter transistor 8 calculates the absorption rate of the blood of the muscle tissue, and the blood sugar level in the blood tissue of the user is obtained according to the absorbance of the blood of the muscle tissue.
- the non-invasive blood glucose concentration detecting auxiliary device includes a control line, a transmitting portion, a spring 4, a rotating shaft 5, a receiving portion, and a controller 14. It should be noted that the numbers of the control line, the transmitting portion and the receiving portion are not shown in Fig. 1.
- the control line includes a transmission control line 1 and a reception control line 13.
- the transmitting portion comprises three parts, namely a transmitting clip holder 2, a launching clip cover 3 and a transmitting triode 8.
- the emitting clip cover 3 covers the transmitting clip holder 2 to form a cavity, and the transmitting PCB board 7 is fixed at the emission.
- the emission control line 1 passes through the cavity between the emitter holder 2 and the emitter cover 3 to the emission PCB board 7, and the emission PCB board 7 is provided with a transmitting transistor 8.
- the transmitting transistor 8 is vertically disposed on the transmitting PCB board 7.
- the receiving portion also includes three parts, a receiving holder 11, a receiving cover 12 and a receiving transistor 9.
- the receiving clip cover 12 covers the receiving holder 11 to form a cavity, and the receiving control line 13 passes through the receiving holder 11 and receives the cavity formed by the clip cover 12 to the receiving PCB 10.
- a receiving PCB board 10 is fixed in the cavity, and a receiving transistor 9 is disposed on the receiving PCB board 10.
- the transmitting transistor 8 and the receiving transistor 9 may be disposed opposite to each other or may be disposed on the same horizontal plane.
- the launching clamp 2 and the receiving clamp 11 are connected by the rotating shaft 5, and the spring 4 is disposed between the transmitting clamp 2 and the receiving clamp 11, and the number of the springs 4 may be two.
- the spring 4 can be arranged in a U-shaped neck shape to improve the stability of the non-invasive blood sugar concentration detecting auxiliary device.
- the two springs 4 are respectively caught in the slots of the lower portion of the transmitting holder 2 and the receiving holder 11, which are not shown in the drawings.
- the upper end of the transmitting holder 2 and the receiving holder 11 can clamp the muscle or tissue of the user under the action of the spring 4, the tissue It can be the position of the tiger's mouth in the hand, or it can be the earlobe.
- One end of the emission control line 1 is connected to the transmitting PCB board 7, and the other end of the transmitting control line 1 is connected to the controller 14 for transmitting an electrical signal sent by the controller 14.
- One end of the receiving control line 13 is connected to the receiving PCB board, and the other end of the receiving control line 13 is connected to the controller 14 for converting the received infrared light through the photoelectric signal to obtain electricity. The signal is then sent to the controller 14 via the receive control line 13.
- the controller 14 transmits a signal to the transmitting transistor of the transmitting portion through the emission control line 1 to cause the transmitting transistor 8 to emit a specific Infrared light, the wavelength of the infrared light is set in the infrared wavelength range, and the specific infrared light can pass through the muscle or tissue of the user.
- the absorption transistor 8 is absorbed.
- the controller 14 sends a signal through the emission control line 1 to control the emission transistor 8 to emit infrared light to illuminate the muscle tissue blood of the user, and according to the receiving transistor 9, blood from the muscle tissue.
- the ratio of the transmitted infrared light to the infrared light emitted from the emitter transistor 8 calculates the absorption rate of the muscle tissue blood.
- the controller 14 obtains the blood sugar level in the blood of the muscle tissue of the user based on the absorbance of the muscle tissue blood to achieve an effect of assisting in determining the current blood sugar level of the user.
- the rubber cover 6 is further disposed on the emitting portion, the rubber sleeve 6 is disposed on the launching cover 3, and the external infrared light is blocked by the rubber sleeve 6 after use, thereby reducing The effect of infrared light on the error in the final determination of blood glucose levels.
- the rubber sleeve 6 is made of soft rubber, which improves the comfort of the user.
- the top of the rubber sleeve 6 is provided with a mouthpiece which is sized to match the firing holder 2, so that the use of sputum does not affect the measurement of blood sugar of the muscle or tissue.
- the non-invasive blood glucose concentration detecting auxiliary device of the invention can clamp the muscle or tissue of the user through the spring, the launching clamp and the receiving clamping seat, and is convenient for the user to operate; the external infrared light is blocked by the rubber sleeve, and the operation is reduced. Due to the influence of infrared light on the final measurement of blood sugar content; through the controller and the emission control line, the transmitting transistor emits specific infrared light, which can pass through the user's muscles or tissues, and part of the infrared light is absorbed by the user's muscles.
- tissue blood glucose absorption part of the infrared light is sent to the receiving triode
- the receiving transistor is converted by the photoelectric signal, and the obtained electric signal is transmitted to the controller through the receiving control line, and the controller processes the electric blood signal to finally obtain the blood sugar content in the blood of the user's muscle or tissue, and assists in judging the current user's current Blood sugar levels.
- the non-invasive blood glucose concentration detecting auxiliary device of the invention has a simple structure and is convenient to use.
- the device can clamp the muscle or tissue of the user through the spring, the launching clamp and the receiving clamp to facilitate the user's operation; the external infrared light is blocked by the rubber sleeve, and the final blood sugar content is determined by infrared light.
- the transmitting transistor emits specific infrared light, which can pass through the muscle or tissue of the user, and part of the infrared light is absorbed by the blood sugar of the user's muscle or tissue, and part of the infrared
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Diabetes (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Surgery (AREA)
- Optics & Photonics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
Dispositif auxiliaire destiné à surveiller de manière non invasive le taux de glycémie comprenant une ligne de commande, une partie d'émission, un ressort (4), un axe rotatif (5), une partie de réception et une commande (14). La ligne de commande comprend un ligne de commande d'émission (1) et une ligne de commande de réception (13), alors qu'une partie d'émission comprend une base (2) d'émission, un couvercle (3) d'émission et une triode (8) d'émission. La partie de réception, quant à elle, comprend une base (11) de pince de réception, un couvercle (12) de réception et une triode (9) de réception, la base (2) d'émission et la base (11) de pince de réception étant connectées au moyen d'un axe rotatif (5). Les muscles ou les tissus de personnes se soumettant au test sont serrés grâce au ressort (4), à la base (2) de pince d'émission et à la base (11) de pince de réception afin de permettre un maniement aisé. Le dispositif auxiliaire permet de déterminer de manière auxiliaire le taux de glycémie actuel chez une personne se soumettant au test.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610096056.0 | 2016-02-20 | ||
CN201610096056.0A CN105548065A (zh) | 2016-02-20 | 2016-02-20 | 无创血糖浓度检测辅助装置 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2017140116A1 true WO2017140116A1 (fr) | 2017-08-24 |
Family
ID=55827406
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2016/103044 WO2017140116A1 (fr) | 2016-02-20 | 2016-10-24 | Dispositif auxiliaire destiné à surveiller de manière non invasive le taux de glycémie |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN105548065A (fr) |
WO (1) | WO2017140116A1 (fr) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN205433707U (zh) * | 2016-02-20 | 2016-08-10 | 深圳市圣必智科技开发有限公司 | 用于无创血糖浓度检测的辅助夹子 |
CN105548065A (zh) * | 2016-02-20 | 2016-05-04 | 深圳市前海安测信息技术有限公司 | 无创血糖浓度检测辅助装置 |
CN205683086U (zh) * | 2016-04-21 | 2016-11-16 | 深圳市前海康启源科技有限公司 | 手持式无创血糖检测装置 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5313940A (en) * | 1991-05-15 | 1994-05-24 | Nihon Kohden Corporation | Photo-electric pulse wave measuring probe |
CN1366177A (zh) * | 2000-12-28 | 2002-08-28 | 株式会社拜奥克斯 | 血糖分光光度测定仪及其测定方法 |
CN204336925U (zh) * | 2014-12-06 | 2015-05-20 | 深圳市易特科信息技术有限公司 | 可穿戴式无创血糖测量设备 |
CN204542107U (zh) * | 2015-03-04 | 2015-08-12 | 邓伟廷 | 适合于手指采样的无创多指标传感器 |
CN105548065A (zh) * | 2016-02-20 | 2016-05-04 | 深圳市前海安测信息技术有限公司 | 无创血糖浓度检测辅助装置 |
CN205433707U (zh) * | 2016-02-20 | 2016-08-10 | 深圳市圣必智科技开发有限公司 | 用于无创血糖浓度检测的辅助夹子 |
-
2016
- 2016-02-20 CN CN201610096056.0A patent/CN105548065A/zh not_active Withdrawn
- 2016-10-24 WO PCT/CN2016/103044 patent/WO2017140116A1/fr active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5313940A (en) * | 1991-05-15 | 1994-05-24 | Nihon Kohden Corporation | Photo-electric pulse wave measuring probe |
CN1366177A (zh) * | 2000-12-28 | 2002-08-28 | 株式会社拜奥克斯 | 血糖分光光度测定仪及其测定方法 |
CN204336925U (zh) * | 2014-12-06 | 2015-05-20 | 深圳市易特科信息技术有限公司 | 可穿戴式无创血糖测量设备 |
CN204542107U (zh) * | 2015-03-04 | 2015-08-12 | 邓伟廷 | 适合于手指采样的无创多指标传感器 |
CN105548065A (zh) * | 2016-02-20 | 2016-05-04 | 深圳市前海安测信息技术有限公司 | 无创血糖浓度检测辅助装置 |
CN205433707U (zh) * | 2016-02-20 | 2016-08-10 | 深圳市圣必智科技开发有限公司 | 用于无创血糖浓度检测的辅助夹子 |
Also Published As
Publication number | Publication date |
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CN105548065A (zh) | 2016-05-04 |
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