WO2017123311A3 - Device based on cellulosic substrate - Google Patents

Device based on cellulosic substrate Download PDF

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Publication number
WO2017123311A3
WO2017123311A3 PCT/US2016/059884 US2016059884W WO2017123311A3 WO 2017123311 A3 WO2017123311 A3 WO 2017123311A3 US 2016059884 W US2016059884 W US 2016059884W WO 2017123311 A3 WO2017123311 A3 WO 2017123311A3
Authority
WO
WIPO (PCT)
Prior art keywords
cellulosic substrate
device based
hydroxyl groups
oligonucleotide
cellulosic
Prior art date
Application number
PCT/US2016/059884
Other languages
French (fr)
Other versions
WO2017123311A2 (en
Inventor
Ana C. GLAVAN
Jia NIU
Zhen Chen
Firat Güder
Chao-Min Cheng
David Liu
George M. Whitesides
Original Assignee
President And Fellows Of Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by President And Fellows Of Harvard College filed Critical President And Fellows Of Harvard College
Publication of WO2017123311A2 publication Critical patent/WO2017123311A2/en
Publication of WO2017123311A3 publication Critical patent/WO2017123311A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/548—Carbohydrates, e.g. dextran
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Laminated Bodies (AREA)

Abstract

A device is described, including: a cellulosic substrate comprising a plurality of hydroxyl groups; and one or more oligonucleotide covalently bonded to one or more of the hydroxyl groups. In certain embodiments, the oligonucleotide is DNA or RNA.
PCT/US2016/059884 2015-11-03 2016-11-01 Device based on cellulosic substrate WO2017123311A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562250063P 2015-11-03 2015-11-03
US62/250,063 2015-11-03

Publications (2)

Publication Number Publication Date
WO2017123311A2 WO2017123311A2 (en) 2017-07-20
WO2017123311A3 true WO2017123311A3 (en) 2017-09-21

Family

ID=59311366

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2016/059884 WO2017123311A2 (en) 2015-11-03 2016-11-01 Device based on cellulosic substrate

Country Status (1)

Country Link
WO (1) WO2017123311A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202000907UA (en) * 2017-08-22 2020-02-27 Elegen Corp Positional tracking and encoding in microfluidic devices

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6444268B2 (en) * 1998-09-01 2002-09-03 Agilent Technologies, Inc. Functionalization of substrate surfaces with silane mixtures
US20030096232A1 (en) * 1997-12-19 2003-05-22 Kris Richard M. High throughput assay system
US20120129704A1 (en) * 2009-04-03 2012-05-24 Illumina, Inc. Generation of uniform fragments of nucleic acids using patterned substrates
WO2013072408A1 (en) * 2011-11-15 2013-05-23 Swetree Technologies Ab Surface-functionalized cellulosic fibres, method of manufacture thereof and uses thereof
WO2013181656A1 (en) * 2012-06-01 2013-12-05 President And Fellows Of Harvard College Microfluidic devices formed from hydrophobic paper
WO2015108597A2 (en) * 2013-10-31 2015-07-23 General Electric Company Substrates and associated methods for elution of nucleic acids
WO2015160684A1 (en) * 2014-04-14 2015-10-22 President And Fellows Of Harvard College Cellulose and cellulosic substrate-based device

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030096232A1 (en) * 1997-12-19 2003-05-22 Kris Richard M. High throughput assay system
US6444268B2 (en) * 1998-09-01 2002-09-03 Agilent Technologies, Inc. Functionalization of substrate surfaces with silane mixtures
US20120129704A1 (en) * 2009-04-03 2012-05-24 Illumina, Inc. Generation of uniform fragments of nucleic acids using patterned substrates
WO2013072408A1 (en) * 2011-11-15 2013-05-23 Swetree Technologies Ab Surface-functionalized cellulosic fibres, method of manufacture thereof and uses thereof
WO2013181656A1 (en) * 2012-06-01 2013-12-05 President And Fellows Of Harvard College Microfluidic devices formed from hydrophobic paper
WO2015108597A2 (en) * 2013-10-31 2015-07-23 General Electric Company Substrates and associated methods for elution of nucleic acids
WO2015160684A1 (en) * 2014-04-14 2015-10-22 President And Fellows Of Harvard College Cellulose and cellulosic substrate-based device

Also Published As

Publication number Publication date
WO2017123311A2 (en) 2017-07-20

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