WO2017059035A1 - Composition comestible contenant une protéine - Google Patents

Composition comestible contenant une protéine Download PDF

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Publication number
WO2017059035A1
WO2017059035A1 PCT/US2016/054382 US2016054382W WO2017059035A1 WO 2017059035 A1 WO2017059035 A1 WO 2017059035A1 US 2016054382 W US2016054382 W US 2016054382W WO 2017059035 A1 WO2017059035 A1 WO 2017059035A1
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WO
WIPO (PCT)
Prior art keywords
composition
protein
present
amount
disclosure
Prior art date
Application number
PCT/US2016/054382
Other languages
English (en)
Inventor
Manoj Bhargava
Marc MUNSON
Erin SIMON
Original Assignee
International Ip Holdings Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by International Ip Holdings Llc filed Critical International Ip Holdings Llc
Publication of WO2017059035A1 publication Critical patent/WO2017059035A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
    • A23L2/52—Adding ingredients
    • A23L2/66—Proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/275—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of animal origin, e.g. chitin
    • A23L29/281—Proteins, e.g. gelatin or collagen
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/13—Nucleic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/15—Vitamins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Definitions

  • these products may include undesirable amounts of Calories due to, for example, the inclusion of sugars, and/or may provide an unpleasant taste and/or may fail to provide sufficient physical and mental benefits for an adequate period of time.
  • the disclosure relates to a composition that includes
  • a protein preparation at least one methylated xanthine, at least two cholines;
  • taurine taurine, phosphoric acid; a vitamins including vitamin B6, vitamin B12, niacin, folic acid phenylalanine and tyrosine and combinations thereof; and an organic acid selected from the group consisting of malic acid and citric acid DETAILED DESCRIPTION
  • compositions that provide protein relate to compositions that provide energy .
  • compositions according to the disclosure provide both energy and protein.
  • compositions according to the disclosure provide at least one methylated xanthine and protein. In further embodiments, compositions according to the disclosure include a methylated xanthine, at least one choline and protein.
  • the disclosure relates to a stable, edible composition.
  • the compositions are provided.
  • compositions disclosed herein may be in liquid or solid form or include both liquid and solid forms.
  • the composition is provided as a liquid such as a dietary supplement, drink, beverage or gel.
  • the liquid compositions may also have a
  • compositions may be served at a wide range of temperatures from freezing (0°C) to up to about 90° C.
  • Compositions may be provided in any mass or volume.
  • the compositions may also be provided as a solid food item in the form of bars, crackers, cookies or similar products, having the mass and shape of these types of products.
  • compositions according to the disclosure may be used as dietary supplements that provide further nutritional value and supplement an individual's diet.
  • the compositions of the disclosure may increase the total dietary intake of certain dietary substances such as, but not limited to, vitamins, protein or amino acids.
  • Compositions of the disclosure provide protein such that an individual may supplement the daily intake of protein.
  • the protein such as, but not limited to, the amino acids
  • the protein may be synthesized in vitro and added to the composition.
  • the protein preparation may be modified after isolation or purification from its source.
  • the protein preparation may be treated to improve solubility or to increase homogeneity with respect to molecular weight of the polypeptides.
  • protein refers to preparations that include polypeptides, including low molecular weight polypeptides to very high molecular weight polypeptides.
  • the protein is obtained, isolated or derived from a biological source.
  • the preparations may originate, be derived from or isolated from animal or vegetable sources.
  • the preparation contains protein derived from at least one animal source and at least one vegetable source.
  • protein is derived from milk.
  • the protein is derived from whey.
  • the protein may be obtained, isolated, purified or derived from whey.
  • the protein may be included in whey isolates that are added to a composition of the disclosure.
  • the whey isolate is largely free of non-protein molecules.
  • the whey may be obtained from milk of a number of animal sources.
  • the whey isolate originates from a bovine source.
  • the whey may also be derived from plant sources such as, but not limited to, soy milk.
  • a vegetable source of protein is potato.
  • compositions of the disclosure include a combination both whey and potato isolates that provide protein.
  • the protein preparation may be a highly purified preparation of a single polypeptide species.
  • the protein preparation is a mixture of polypeptide species.
  • a protein preparation may also include other constituents such as carbohydrate or fat molecules.
  • the protein preparations may include glycoproteins, lipoproteins or other modified polypeptides, including phosphorylated polypeptides.
  • compositions according to the disclosure provide from about 5 grams of protein to about 100 grams of protein per serving.
  • compositions according to the disclosure have from about 10 grams of protein to about 50 grams of protein per serving. In further embodiments, compositions according to the disclosure have from about 15 grams of protein to about 30 grams of protein per serving. In preferred embodiments, the composition contains about 21 g of protein per serving.
  • compositions according to the disclosure provide about 10% to about 100% of the recommended daily requirement for protein for a particular individual. In other embodiments, compositions according to the disclosure provide about 25% to about 75% of the daily requirement for protein. In preferred embodiments, the compositions provide about 25% to about 50% of the full recommended daily requirement for protein.
  • the volume of compositions according to the disclosure may be from about 50 ml to about 500 ml. In further embodiments, the volume of a composition which includes protein may be from about 100 ml to about 300 ml. In yet further embodiments, the volume of a composition which includes protein may be from about 100 ml to about 200 ml.
  • compositions according to the disclosure may deliver a total of from about 10 kcal to about 300 kcal (about 10 to 300 Calories). In preferred embodiments, a compositions of the disclosure may deliver a total of from about 50 kcal to about 200 kcal per serving. In preferred embodiments, compositions of the
  • compositions according to the disclosure may deliver a total of from about 75 kcal to about 150 kcal.
  • a composition with protein has about 100 kcal (or about 100 Calories).
  • Compositions according to the disclosure deliver about 0.02 kcal/ml to about 6.0 kcal/ml. In further embodiments, compositions according to the disclosure deliver deliver about 0.1 kcal/ml to about 4.0 kcal/ml
  • the addition of protein results in the addition of less than about 5 g of carbohydrates and less than about 2 g of sugars per serving. In further preferred embodiments the composition has less than about 3 g of carbohydrates and about 1 g of sugars per serving.
  • compositions according to the disclosure include an energy component.
  • Compositions according to the disclosure may counter, reduce or prevent drowsiness.
  • the compositions may also provide a feeling of alertness and mental acuity.
  • the composition may also provide a significant increase in the power of attention, continuity of attention, quality of working memory, quality of episodic memory, speed of memory and self-related alertness, the sum of the benefits providing a perceived feeling of energy.
  • the energy component includes at least one methylated xanthine.
  • Methylated xanthines include but are not limited to caffeine, theobromine, aminophylline, theophylline and paraxanthine.
  • the methylated xanthine is present in an amount from about 0.016% to about 0.5 % by weight (i.e. w/w) (or for some liquid forms from about 0.016 mg/ml to about 5.0 mg/ml).
  • the methylated xanthine is present in an amount from about 0.05 % to about 0.45% w/w (or from about 0.05 mg/ml to about 4.5 mg/ml).
  • the methylated xanthine is present in an amount from about 0.10 % to about 0.39% (or from about 0.10 mg/ml to about 3.9 mg/ml) or the methylated xanthine is present in an amount from about 0.08 % to about 0.34 % by weight (or from about 0.8 mg/ml to about 3.4 mg/ml).
  • the methylated xanthine may be present from 0.002 mg/ml to about 0.02 mg/mt.
  • the the methylated xanthine may be present from 0.008 mg/ml to about 0.015 mg/ml.
  • Compositions of the disclosure may also include a choline.
  • compositions according to the disclosure may have more than one choline.
  • the compositions may have two different cholines, three different cholines , or as many as four different cholines.
  • compositions may utilize citicoline and a salt of choline.
  • compositions according to the disclosure utilize citicoline and choline bitartrate.
  • the cholines may be present in equal proportions or one choline may be present in larger amounts than other cholines.
  • one or more cholines are present from about 0.1% to 0.5%.
  • choline is present in an amount from about 0.0015% to about 0.09% by weight or from about 0.000015 g/ml to about 0.0009 g/ml.
  • choline is present in an amount from about 0.01 % to about 0.07% by weight or from about 0.1 mg/ml to about 0.7 mg/ml.
  • the choline is present in an amount from about 0.013% to about 0.06% by weight (or from about 0.13 mg/ml to about 0.6 mg/ml).
  • the choline is present from about 0.1% to 0.5%.
  • the choline is present in an amount from about 0.0015% to about 0.09% by weight or from about 0.000015 g/ml to about 0.0009 g/ml.
  • choline is present in an amount from about 0.01 % to about 0.07% by weight or from about 0.1 mg/ml to about 0.7 mg/ml.
  • compositions according to the disclosure may include two or more cholines.
  • compositions according to the disclosure include citicoline and choline bitartrate.
  • the composition has from about 1 mg ml of choline bitartrate to about 4 mg/ml or from about 0.1% to 0.4% by weight.
  • .Citicoline may be present 0.0002% to about 0.09% by weight
  • the composition may have from about 200 mg to about 500 mg of choline bitartrate in six (6) fluid ounces.
  • the composition may have about 5 to about 30 mg of citicoline in addition to the choline bitartrate.
  • the composition may further include one or more amino acids including, without limitation, precursors, structurally-similar compounds and analogs, metabolites, salts, esters or isomeric forms of amino acids.
  • the amino acids include, but are not limited to, N-acetyl L- tyrosine, tyrosine and phenylalanine.
  • amino acids are present in an amount from 0.016% to 5.0% by weight or from about 0.16 mg /ml to about 50 mg/ml.
  • amino acids are present in an amount from about 0.1 % to about 4% by weight (or from about 1.0 mg/ml to about 40.0 mg/ml).
  • the edible composition includes N-acetyl L-tyrosine in an amount from about 0.03% to about 0.8% by weight (or about 0.3 mg/ml to about 8 mg/ml). In another embodiment, N-acetyl L-tyrosine is present in an amount from 0.06% to about 0.6% (or from about 0.6 mg/ml to about 6.0 g/ml). In still another embodiment, N-acetyl L-tyrosine is present in an amount from about 0.1% to about 0.5% by weight (or from about 1.0 mg/ml to about 5.0 mg/ml).
  • taurine is present in an amount from about 0.13 % to about 1.2 % by weight (or from about 1.3 mg/ml to about 12.0 mg/ml). In still another embodiment, taurine is present in an amount from about 0.2 % to about 1.0 % (or from about 2.0 mg/ml to about 10 mg/ml).
  • the composition includes vitamin B12.
  • Vitamin B12 exists in several forms containing the mineral cobalt, e.g. methylcobalamin and 5- deoxyadenosylcobalamin.
  • the composition may include niacin, also known as nicotinic acid or vitamin B3 and derivatives of niacin, including precursors, structurally related compounds; analogs and metabolites, including niacinamide.
  • compositions according to the disclosure may include vitamin B6.
  • the B6 is present in an amount from about 0.003 % to about 0.3 %( or from about 0.03 mg/ml to about 3.0 mg/ml).
  • the vitamin B6 is present in an amount from about 0.01 % to about 0.2 % (or from about 0.1 mg/ml to about 2.0 mg/ml).
  • the vitamin B6 is present in an amount from about 0.02 % to about 0.09 % (or from about 0.2 mg/ml to about 0.9 mg/ml).
  • the composition may provide from about 20% to about 3000% of the recommended daily allowance of vitamin B6.
  • compositions according to the disclosure may include vitamin B12.
  • the B12 is present in an amount from about 0.00003 % to about 0.003 % (or from about 0.000003 g/ml to about 0.00003 g/ml). In another embodiment, the B12 is present in an amount from about 0.0001 % to about 0.002 % (or from about 0.00001 g/ml to about 0.00002 g/mi). In still another embodiment, the B12 is present in an amount from about 0.0002 % to about 0.001 % (or from about 0.000002 g/ml to about 0.00001 g/ml). The composition may provide from about 20% to about 10000% of the recommended daily allowance of vitamin B12.
  • compositions according to the disclosure may include niacin, which includes niacinamide.
  • niacin is present in an amount from about 0.000003 % to about 0.3 % (or from about 0.00003 mg/ml or from about 3.0 mg/ml).
  • the niacin is present in an amount from about 0.003 % to about 0.3 % (or about 0.003 mg/m! to about 3.0 g/ml).
  • the niacin is present in an amount from about 0.01 % to about 0.2 % (or about 0.1 mg/ml to about 2.0 mg/ml).
  • the niacin is present in an amount from about 0.02 % to about 0.09 % (or about 0.2 mg/ml to about 0.9 mg/ml).
  • the composition may provide from about 7% to about 300% of the
  • the energy composition may include folic acid.
  • folic acid is present in an amount from about 0.000003% to about 0.02 % (or about 0.00003 mg/ml to about 0.2 mg/ml).
  • folic acid is present in an amount from about 0.00016 % to about 0.02 % (or about 0.0016 mg/ml to about 0.2 mg/ml).
  • the folic acid is present in an amount from about 0.0003 % to about 0.008 % (or about 0.003 mg/ml to about 0.08 mg/ml).
  • compositions of the disclosure include additional components that may reduce fatigue and provide energy.
  • additional components may include, for example, one or more of glucuronolactone, glucono delta-lactone, and glucuronic acid.
  • glucuronolactone is present in an amount from about 0.03% to about 1.2 % (or from about 0.3 mg/ml to about 0. 12 mg/ml).
  • glucuronolactone is present in an amount from about 0.0003 to about 0.09 %. (or from about 0.003 mg/ml to about 0.9 mg/ml).
  • glucuronolactone is present in an amount from about 0.05 % to about 0.7 % (or from about 0.0016 g g/ml to about 0.007 g/ml).
  • the pH of the composition is from about 1.0 to about 9.0.
  • the pH of the composition is acidic.
  • the pH may be from about 2.0 to about 4.0.
  • the energy composition may further include one or more pH-mod ' rfying components.
  • the pH-mod ' rfying components are acidulants.
  • Suitable pH-modifying components include edible inorganic acids, such as phosphoric acid.
  • the composition includes edible organic acids. Preferred embodiments of edible organic acids include malic acid and citric acid.
  • the pH-modifying components are presentTM an amount from about 0.03% to about 1.2% or from about 0.0003 g/ml to about 0.012 g/ml. In one embodiment, the pH-modifying components are present in an amount from about 0.1% to about 0.9 % (or from about 0.001 to about 0.009 g/ml). In still another embodiment the pH-modifying components are present in an amount from about 0.13 to about 0.7 % (or from about 0.0013 g/ml to about 0.007 g/ml).
  • the flavorants are present in an amount from about 0.00003% to about 0.8 % (or about 0.00000003 g/ml to about 0.008 g/ml). In another embodiment, the flavorants are present in an amount from about 0.3% to about 0.8 %.
  • nutritive or non-nutritive sweeteners may be added. [Examples of such sweeteners include, but are not limited to xyiitol, stevia, aspartame, sucralose and other non-nutritive sweeteners known to those of ordinary skill in the art. In preferred embodiments, sucralose may be used.
  • sucralose is present in an amount from 0.0003% to about 0.4 % (or about 0.003 mg/ml to about 4.0 mg/ml). In one embodiment, sucralose is present in an amount from about 0.016% to about 0.4 % (or about 0.16 mg/ml to about 4.0 mg/ml). In one embodiment, sucralose is present in an amount from about 0.026% to about 0.3 % (or about 0.26 mg/ml to about 3.0 mg/ml). In still another embodiment, sucralose is present in an amount from about 0.03 % to about 0.2 % (or about 0.3 mg/ml to about 2.0 mg/ml).
  • preservative agents may be added to the composition.
  • Ethylene diamine tetraacetic acid (“EDTA”) may also be included to improve flavor and stability.
  • EDTA is present in an amount from about 0.0007 % to about 0.009 % (or about 0.000007 g/ml to about 0.00009 g/ml).
  • the EDTA is present in an amount from about 0.001 % to about 0.007 % (or about 0.01 mg/ml to about 0.07 mg/ml).
  • the EDTA is present in an amount from about 0.0013 % to about 0.006 % (or about 0.013 mg/ml to about 0.06 mg/ml).
  • the EDTA is present in an amount from about 0.0007 % to about 0.003 % (or about 0.007 mg/ml to about 0.03 mg/ml).
  • the energy composition also includes one or more fruit flavorants.
  • fruit flavorants include, but are not limited to lemon lime flavors, orange flavors, berry flavors, high fructose corn syrup, raspberry juice concentrates, berry juice concentrates and the like.
  • the energy composition may further include at least one preservative.
  • the preservative is a natural preservative.
  • Embodiments of useful preservatives include, but are not limited to, benzoic acid and benzoic acid derivatives such as sodium benzoate, calcium benzoate, potassium benzoate, magnesium benzoate, and combinations thereof.
  • the preservative may include sorbic acid derivatives such as potassium sorbate.
  • the preservative is present in an amount from about 0.003 % to about 1.0 % (or from about 0.00003 g/ml to about 0.01 g/ml).
  • the preservative is present in an amount from about 0.03 % to about 0.8 %.
  • the preservative is phosphoric acid.
  • the preservative is present from about 0.001% to about 5% by weight.
  • the phosphoric acid is present from about 0.02% to about 1% by weight
  • the composition may also include a bicarbonate, such as sodium bicarbonate.
  • phosphoric acid also acts as a processing aid.
  • phosphoric acid is flavorant.
  • compositions of the disclosure may also include phosphoric acid as a preservative, processing aid and as a flavorant
  • phosphoric acid may be present from about 0.001% to about 5% by weight.
  • the phosphoric acid is present from about 0.02% to about 1% by weight
  • a composition of the disclosure may also include a bicarbonate, such as sodium bicarbonate.
  • the protein-containing energy composition does not contain glucuronolactone or glucuronic acid.
  • the composition may have incidental or trace amounts of glucuronolactone or glucuronic acid that originates from other components such as protein isolates.
  • Table 1 provide a non-limiting set of components that may be introduced into a composition encompassed by this disclosure. The amounts provided in table 1 are particularly useful to form compositions having a total final volume of about 6 fluid ounces.

Abstract

La présente invention concerne une composition comestible qui comprend une protéine et un mélange d'énergie.
PCT/US2016/054382 2015-09-29 2016-09-29 Composition comestible contenant une protéine WO2017059035A1 (fr)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562234395P 2015-09-29 2015-09-29
US201562234605P 2015-09-29 2015-09-29
US62/234,395 2015-09-29
US62/234,605 2015-09-29
US201562242623P 2015-10-16 2015-10-16
US62/242,623 2015-10-16

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WO2017059035A1 true WO2017059035A1 (fr) 2017-04-06

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4093296A4 (fr) * 2020-01-23 2024-01-24 Ingenious Ingredients Lp Composition bioactive à base de paraxanthine et son procédé d'utilisation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7445907B2 (en) * 2001-04-17 2008-11-04 Ista S.P.A. Methods for mass spectrometry detection and quantification of specific target proteins in complex biological samples
US20100285179A1 (en) * 2007-11-16 2010-11-11 Bioclinical Development, Inc Edible energy composition with low caffeine
WO2015053789A1 (fr) * 2013-10-11 2015-04-16 Abbott Laboratories Composition nutritive pour femmes enceintes ayant un profil de glucose et d'insuline bénéfique
US20150265646A1 (en) * 2008-06-13 2015-09-24 International Ip Holdings Llc Edible Energy Composition

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7445907B2 (en) * 2001-04-17 2008-11-04 Ista S.P.A. Methods for mass spectrometry detection and quantification of specific target proteins in complex biological samples
US20100285179A1 (en) * 2007-11-16 2010-11-11 Bioclinical Development, Inc Edible energy composition with low caffeine
US20150265646A1 (en) * 2008-06-13 2015-09-24 International Ip Holdings Llc Edible Energy Composition
WO2015053789A1 (fr) * 2013-10-11 2015-04-16 Abbott Laboratories Composition nutritive pour femmes enceintes ayant un profil de glucose et d'insuline bénéfique

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4093296A4 (fr) * 2020-01-23 2024-01-24 Ingenious Ingredients Lp Composition bioactive à base de paraxanthine et son procédé d'utilisation

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