WO2017040947A1 - Cofabrication de composants électroniques et microfluidiques de papier - Google Patents

Cofabrication de composants électroniques et microfluidiques de papier Download PDF

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Publication number
WO2017040947A1
WO2017040947A1 PCT/US2016/050133 US2016050133W WO2017040947A1 WO 2017040947 A1 WO2017040947 A1 WO 2017040947A1 US 2016050133 W US2016050133 W US 2016050133W WO 2017040947 A1 WO2017040947 A1 WO 2017040947A1
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WIPO (PCT)
Prior art keywords
region
cellulose matrix
channels
paper
electrochemical
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Application number
PCT/US2016/050133
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English (en)
Inventor
Mahiar Max HAMEDI
Philipp ROTHEMUND
Victoria CAMPBELL
Firat GUDER
Dionysios CHRISTODOULEAS
Jean-francis BLOCH
Alar Ainla
Maria Teresa FERNANDEZ-ABEDUL
George M. Whitesides
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President And Fellows Of Harvard College
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Publication of WO2017040947A1 publication Critical patent/WO2017040947A1/fr

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B29/00—Layered products comprising a layer of paper or cardboard
    • B32B29/06—Layered products comprising a layer of paper or cardboard specially treated, e.g. surfaced, parchmentised
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B3/00—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar form; Layered products having particular features of form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B27/10—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of paper or cardboard
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00—Layered products comprising a layer of synthetic resin
    • B32B27/16—Layered products comprising a layer of synthetic resin specially treated, e.g. irradiated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B29/00—Layered products comprising a layer of paper or cardboard
    • B32B29/002—Layered products comprising a layer of paper or cardboard as the main or only constituent of a layer, which is next to another layer of the same or of a different material
    • B32B29/005—Layered products comprising a layer of paper or cardboard as the main or only constituent of a layer, which is next to another layer of the same or of a different material next to another layer of paper or cardboard layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B3/00—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar form; Layered products having particular features of form
    • B32B3/26—Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar form; Layered products having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layer; characterised by a layer with cavities or internal voids ; characterised by an apertured layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B5/00—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
    • B32B5/14—Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by a layer differing constitutionally or physically in different parts, e.g. denser near its faces
    • B32B5/145—Variation across the thickness of the layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2250/00—Layers arrangement
    • B32B2250/02—2 layers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2255/00—Coating on the layer surface
    • B32B2255/02—Coating on the layer surface on fibrous or filamentary layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2255/00—Coating on the layer surface
    • B32B2255/12—Coating on the layer surface on paper layer
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2264/00—Composition or properties of particles which form a particulate layer or are present as additives
    • B32B2264/02—Synthetic macromolecular particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2264/00—Composition or properties of particles which form a particulate layer or are present as additives
    • B32B2264/02—Synthetic macromolecular particles
    • B32B2264/0214—Particles made of materials belonging to B32B27/00
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2264/00—Composition or properties of particles which form a particulate layer or are present as additives
    • B32B2264/10—Inorganic particles
    • B32B2264/102—Oxide or hydroxide
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2264/00—Composition or properties of particles which form a particulate layer or are present as additives
    • B32B2264/10—Inorganic particles
    • B32B2264/104—Oxysalt, e.g. carbonate, sulfate, phosphate or nitrate particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2264/00—Composition or properties of particles which form a particulate layer or are present as additives
    • B32B2264/10—Inorganic particles
    • B32B2264/105—Metal
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2264/00—Composition or properties of particles which form a particulate layer or are present as additives
    • B32B2264/10—Inorganic particles
    • B32B2264/107—Ceramic
    • B32B2264/108—Carbon, e.g. graphite particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/20—Properties of the layers or laminate having particular electrical or magnetic properties, e.g. piezoelectric
    • B32B2307/202—Conductive
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/726—Permeability to liquids, absorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/73—Hydrophobic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2307/00—Properties of the layers or laminate
    • B32B2307/70—Other properties
    • B32B2307/732—Dimensional properties
    • B32B2307/734—Dimensional stability
    • B32B2307/736—Shrinkable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2457/00—Electrical equipment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2457/00—Electrical equipment
    • B32B2457/08—PCBs, i.e. printed circuit boards
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B32—LAYERED PRODUCTS
    • B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2457/00—Electrical equipment
    • B32B2457/10—Batteries

Definitions

  • Paper is an abundant, lightweight, and biodegradable material that has been used for centuries for printing, packaging, and absorbing liquids. It is composed of intertwined cellulose fibers that form a porous hydrophilic network that define the mechanical and fluidic properties of this material.
  • paper has become increasingly interesting as a material for new applications. For example, paper has been used for microfluidic devices, as 3-D scaffolds for cell growth, as a substrate for printed electronics, and in micro- electromechanical systems (MEMS).
  • MEMS micro- electromechanical systems
  • paper fluidics and electronics have historically developed separately, and the techniques developed for their fabrication are incompatible in many respects. Many factors contribute to this incompatibility.
  • the paper fluidics are related to transporting water, whereas the electronics are related to transport of charges, holes, and/or electrons.
  • the electrical conductors are printed on the surface of the paper, while paper fluidics use structures formed by hydrophobic barriers that penetrate the paper.
  • a device in an embodiment, includes a substrate comprising a cellulose matrix that provides an interconnected porous structure, a hydrophobic barrier disposed through the thickness of the substrate to define at least one porous channel within the volume of the cellulose matrix, and an electrically conducting material.
  • the electrically conducting material is disposed within the volume of the porous channel to coat at least a portion of the cellulose matrix therein.
  • the hydrophobic barrier is made of a wax, a thermosetting resin, or a UV cured resin.
  • the electrically conducting material can be a nanoparticulate carbon, a conducting polymer, a metallic dust, or metallic nanoparticles.
  • the electrically conducting material comprises carbon black or carbon nanotubes.
  • the electrically conducting material is the polymer poly(3,4-ethylenedioxythiophene):poly(styrenesulfonic acid).
  • the cellulose matrix can have a first side and a second side, wherein one of the first side or the second side has a barrier layer.
  • the barrier layer is a coating or a film.
  • the device further includes a fold which forms a first region and a second region on the device.
  • an actuator including any of the devices described above further includes a controller configured to control a flow of electricity through the electrically conducting material as a function of a temperature and a relative humidity.
  • the hygroscopic pick-up of moisture by the cellulose matrix in the channels causes the cellulose matrix to swell, and said swelling of the cellulose matrix can be configured to produce a change in a shortest distance along at least one dimension of the actuator.
  • said swelling of the cellulose matrix results in the first region and the second region of the device to move towards or away from each other about the fold, and said moving towards and away from each other about the fold can change the shortest distance along at least one dimension of the actuator.
  • the flow of electricity through the electrically conducting material results in an electrothermal heating of the cellulose matrix in the channels.
  • the electrothermal heating of the cellulose matrix can cause a reduction in the moisture content which causes a shrinkage in the cellulose matrix.
  • the shrinkage in the cellulose matrix can thereby restore the shortest distance along at least one dimension of the actuator to its original state.
  • an electrochemical sensor can include any of the devices set for the herein, and the device can further include a first region of channels in the cellulose matrix that are configured to form a working electrode; a second region of channels in the cellulose matrix that are configured to form a separator; and a third region of channels in the cellulose matrix that are configured to form a counter electrode.
  • the first region, the second region and the third region can be in an electrochemical contact with each other.
  • the electrochemical sensor further includes a reference electrode.
  • the reference electrode includes Ag/AgCl.
  • a battery can include any of the devices described herein, wherein the device further includes a first region of channels in the cellulose matrix that are configured to form a cathode; a second region of channels in the cellulose matrix that are configured to form a separator; a third region of channels in the cellulose matrix that are configured to form an anode; and an electrolyte disposed in the first region, the second region and the third region, wherein the first region, the second region and the third region are in an
  • the cellulose matrices in the channels in the first region, the second region and the third region are coated with similar or different electrically conducting materials.
  • the method of making a device includes providing a substrate including a cellulose matrix that provides an interconnected porous structure, providing a hydrophobic barrier disposed through the thickness of the substrate to define at least one porous channel within the volume of the cellulose substrate, and providing an electrically conducting material, wherein the electrically conducting material is disposed within the volume of the porous channel to coat at least a portion of the cellulose matrix therein.
  • the hydrophobic barrier is made of a wax, a thermosetting resin, or a UV cured resin.
  • the electrically conducting material can comprise a nanoparticulate carbon, a conducting polymer, a metallic dust, and/or metallic nanoparticles.
  • the electrically conducting particle can include carbon black or carbon nanotubes.
  • the electrically conducting particle is the polymer poly(3,4-ethylenedioxythiophene):poly(styrenesulfonic acid).
  • the cellulose matrix has a first side and a second side, and a barrier layer is disposed on one of the first side or the second side.
  • the barrier layer is disposed on the cellulose matrix as a coating or a film.
  • the method can further include forming a fold in the device that forms a first region and a second region on the device.
  • the electrically conducting material can be introduced into the channels of the cellulose matrix as an ink.
  • the ink is an aqueous solution or a solvent-based solution.
  • a method of making an electrochemical sensor includes providing any of the devices described above, wherein the device further includes a first region of the porous channel in the cellulose matrix that is configured to form a working electrode; a second region of the porous channels in the cellulose matrix that is configured to form a separator; a third region of the porous channel in the cellulose matrix that is configured to form a counter electrode; and a reference electrode, wherein the first region, the second region, the third region and the reference electrode are in an electrochemical contact.
  • electrochemical sensors described above includes further providing a loading electrolyte that enters the porous channels of the first region, the second region and the third region to produce a first interaction with the electrically conducting material disposed therein. Said first interaction can produce a baseline electrochemical signal.
  • the method can further include performing an electrochemical measurement to measure the baseline electrochemical signal, providing an analyte sample that enters the porous channels of the working electrode to produce a second electrochemical signal, and analyzing the second electrochemical signal and comparing it with the baseline electrochemical signal to gather information regarding the analyte.
  • measuring an electrochemical signal comprises an impedance measurement, a current measurement or the measurement of voltage.
  • the electrochemical measurement is selected from the group consisting of: amperometry, biamperometry, stripping voltammetry, differential pulse voltammetry, cyclic voltammetry, coulometry, chronoamperometry, and potentiometry.
  • the electrochemical measurement is chronoamperometry
  • the analyte comprises glucose, cholesterol, uric acid, lactate, blood gases, DNA, hemoglobin, nitric oxide, and/or blood ketones.
  • the measuring an electrochemical signal can comprise anodic stripping voltammetry.
  • a method of making an battery includes: (1) providing any of the devices described above, wherein the device further includes: a first region of channels in the cellulose matrix that are configured to form a cathode; a second region of channels in the cellulose matrix that are configured to form a separator; and a third region of channels in the cellulose matrix that are configured to form an anode, wherein the first region, the second region and the third region are in an electrochemical contact with each other; and (2) providing an electrolyte to be deposited in the channels formed within the cellulose matrix.
  • the cathode and/or anode are formed by reacting the electrically conducting material with a chemical reagent to change its oxidative state.
  • the electrically conductive material is PEDOT and the chemical reagent is polyenimine (PEI).
  • the electrolyte is a salt solution.
  • a printed circuit board includes the device in accordance with any of devices described above, and further includes a microprocessor or a microcontroller, wherein the microprocessor or the microcontroller controls a flow of electricity through the device.
  • a method of making a printed circuit board includes providing any of the devices described above, and further includes providing a microprocessor or a
  • microcontroller wherein the microprocessor or the microcontroller controls the flow of electricity through the device.
  • FIG.l shows a schematic of the device in accordance with this disclosure
  • FIG. 2A shows a schematic representation of the fabrication of the
  • FIG. 2B shows an image of the wax patterned channel
  • FIG. 2C shows an image of the patterned channel with conducting polymer poly(3,4-ethylenedioxythiophene):poly(styrenesulfonic acid) (PEDOT);
  • FIG. 2D shows an image of the cross section showing PEDOT embedded in the paper channel
  • FIG. 2E shows the schematic representation of the three HEP As (straight, pre- curved, and creased), and of their motion of actuation;
  • FIG.3A shows the infrared (IR) thermal images demonstrating uniform distribution of heat across the surface of the conducting path
  • FIG. 5B shows the number of on / off cycles vs. normalized light intensity calculated from the videos of actuation.
  • FIG. 5C shows the time lapse images of the HEPA optical shutter during operation with the device placed on a backlit table, and light visible only when the shutter is open (The dashed-lines highlight the shutter area);
  • FIG. 6 shows the resistance measured as a function of the fold angle
  • FIG. 7A shows the time-lapse images of a folded/creased-circularHEPA fabricated with tape on one side operated at 100 V at 1W, and RH of 30-40% (dashed lines highlight the attached passive paper);
  • FIG. 7B shows the time-lapsed images of a folded/creased-linear HEPA fabricated with the tape positioned on alternating sides operated at 100 V at 1W, and RH of 30-40% (dashed lines highlight the attached passive paper);
  • FIG. 8A is a schematic diagram of an embodiment of a fabrication procedure for making an electronic pattern
  • FIGS. 8B-8D are images of the printed structures with top view (bottom) and cross sections (top);
  • FIG. 8E shows a schematic diagram, and images (top and side view) of a water droplet placed on a printed electronic pattern
  • FIG. 8F shows a schematic of a 2 layer paper device showing 3D wicking in electrofluidic structures (top) and time-lapse photos of same electrofluidic 3D assemblies, showing transport of water through the top and bottom paper layers in carbon printed
  • FIG. 8G shows the relative resistance measured across electronic structures on paper with a water drop on top (see the structure in figure FIG. 8E) for an electronic pattern with MWNT (Solid line) and PEDOT (dashed line);
  • FIGS. 9A and 9B show a printed multi-layer paper circuit board;
  • FIG. 9C shows an assembled printed multi-layer paper circuit board
  • FIG.10A shows a schematic diagram for the assembly and operation of a printed, three-layer flow-through electrochemical analytical paper sensor
  • FIG. 10B shows the image of the sensor before folding into the final structure, shown on the right, which is further connected to three copper clips;
  • FIG. IOC shows the chronoamperometry for ferrocyanide in lxPBS (error bars calculated based on measurement of 3 different devices); and the red line shows the theoretical value of the total amounts of charge per analyte;
  • FIG. 10D shows the chronoamperometry for a glucose assay (error bars extracted from 3 devices) and the red line represents a linear fit
  • FIG. 11 shows a capacitive discharge curve for a conducting polymer 2 electrode sensor, such as, PEDOT, (dashed line ) and a carbon 2 electrode sensor, such as, MWNTs (solid line), results of the samples in cyclic voltammetry are shown in the inset (right, PEDOT and, left, MWNTs);
  • FIG. 12 A shows a schematics diagram of the assembly of a printed paper battery, using folding
  • FIGS. 12B-12D show images of a fully printed device, that contains six serial connected batteries, before folding, during folding, and folded, respectively;
  • FIG. 12 E shows the equivalent circuit of the device shown in FIG. 12D
  • FIG. 13 shows the constant current (5 ⁇ ) discharge curve of for six serially connected batteries similar to the ones shown in FIG. 12;
  • FIG. 14A shows a circuit diagram for a microcontrolled heating device
  • FIG. 14B shows images of a printed paper circuit being folded to form a final device having all the components on one side and a fluidic channel on the other/opposite side;
  • FIG. 14C is an image of the device shown in FIG. 14A, where all the wires are printed in paper, and the electrical components are mounted on one side using a conductive glue; and
  • FIG. 14D shows, on the left, images showing drops of water placed in the fluid reservoir with a pipette, which upon reaching the fluid detector, starts the heating cycle as shown on the right, through the IR images.
  • a device in an aspect, includes a substrate including a cellulose matrix that provides an interconnected porous structure, a hydrophobic barrier disposed through the thickness of the substrate to define at least one porous channel within the volume of the cellulose matrix, and an electrically conducting material, wherein the electrically conducting material is disposed within the volume of the porous channel to coat at least a portion of the cellulose matrix therein.
  • FIG.l shows a schematic of the device 100 in accordance with this disclosure.
  • FIG. 1 shows a substrate 110 including a cellulose matrix 111 where a hydrophobic barrier 120 is disposed through thickness of the substrate.
  • the hydrophobic barrier 120 defines at least one porous channel 112 within the volume of the cellulose matrix 111 .
  • An electrically conducting material 130 is disposed within the volume of the porous channel to coat at least a portion of the cellulose matrix therein.
  • the substrate 100 including a cellulose matrix is paper. Any variety of paper may be selected for the purpose of use as a substrate as long as one of the surfaces of the paper is uncoated, providing access to the interconnected porous structure inside the cellulose matrix. In some embodiments, it may be preferred to have one of the sides of the paper coated or filled with a barrier coating or film.
  • the paper can also include inorganic additives such as, talc, silica, calcium carbonate, titanium dioxide, kaolinite, bentonite, montmorillonite, clay, etc. In some other embodiments, the paper may also contain polymeric fibers to enhance the mechanical strength of the resulting device.
  • the hydrophobic barrier 120 layer comprises wax, a thermosetting resin or a UV cured resin. Additional additives may be added to the wax to further tune the hydrophobicity of the hydrophobic barrier.
  • the electrically conducting material 130 is made of nanoparticulate carbon, a conducting polymers, a metallic dust, or a metallic nanoparticles. In some other embodiments, the electrically conducting material 130 is carbon black, or carbon nanotubes. In some other embodiments, the electrically conducting particle is polymer poly(3,4-ethylenedioxythiophene):poly(styrenesulfonic acid).
  • the device further includes a fold that forms a first region and a second region on the device.
  • Microfluidic using the cellulose matrix for e.g., in paper, as 3-D scaffolds for cell growth, as a substrate for printed electronics, and in micro-electromechanical systems (MEMS) are known.
  • MEMS micro-electromechanical systems
  • a type of component for cellulose matrix-based devices that is still missing is an electrically controlled actuator that can be embedded within the cellulose matrix, can be fabricated by simple processes, such as, roll-coating, gravure coating or printing, and that is unaffected by creasing.
  • Cellulose matrix based actuators that fulfill these requirements have the potential to allow control of liquid transport in paper- based microfluidic devices, to enable assembly of micro machines through self- folding, and to actuate MEMS and paper robots.
  • this disclosure describes a new class of devices that have the ability to perform mechanical work with cellulose matrix based materials, such as, paper.
  • actuators are made by integrating magnetic particles in paper. The actuation in these systems is achieved by (and requires) an external magnetic field. This approach produces tunable composite materials, but requires large quantities of magnetic additives, and the application and control of a localized external magnetic field: this control is difficult and/or inconvenient to accomplish,
  • Electrostatic zippers consist of two sheets of paper that are coated with carbon nanotubes and are separated by a dielectric layer. They actuate using electrostatic fields.
  • Electroactive papers These structures are fabricated by printing electrodes (usually made from gold) on both sides of paper or of cellulose films. They are lightweight and flexible, but have the drawback that they require a metallic electrode. This requirement adds to both their cost and complexity, their performance degrades over time, and they do not function when creased. Because paper is hydrophilic, most systems based on it are affected by the relative humidity (RH) of the environment; variations in the RH render their actuation difficult to control, and lower their reliability.
  • RH relative humidity
  • an actuator includes any of the above described devices and further includes a controller configured to control a flow of electricity through the electrically conducting material as a function of a temperature and a relative humidity.
  • the electrically activated paper actuators exploit the hydrophilicity of paper, and operate based on its hygroexpansion, i.e., they expand or contract based on the moisture content of the cellulose matrix. These actuators have also been referred to as "Hygroexpansive Electrothermal Paper Actuators" (HEP As) throughout this manuscript. These simple devices are lightweight, inexpensive, and resistant to bending and scratching.
  • the hygroscopic pick-up of moisture by the cellulose matrix in the channels results in the cellulose matrix to swell.
  • the actuator is configured to produce a change in the shortest distance along at least one dimension.
  • the hygroscopic pick-up of moisture by the cellulose matrix in the channels results in the cellulose matrix to swell; and the swelling of the cellulose matrix subsequently results in the first region and the second region of the device to move towards or away from each other about the fold.
  • the change in the shortest distance along at least one dimension could mean an elongation in the shortest distance due to straightening of the actuator or reduction in the shortest distance because of curling of the actuator.
  • the change in the shortest distance along at least one dimension could mean an elongation in the shortest distance due to opening of the actuator or reduction in the shortest distance because of closing of the actuator.
  • a hydrophobic barrier is formed in a cellulose matrix, such as a paper.
  • wax printing is used to form a fluidic "U-shaped" channel is in the cellulose matrix.
  • the paper when paper is used as the cellulose matrix, the paper may be a Chromatography Paper Grade A. This type of paper is composed of pure cellulose, and has no inorganic additives. Its hygroexpansive properties are, therefore, defined entirely by the cellulose fibers, and the arrangement of the fibers in the paper sheet.
  • actuators included in this disclosure use a Chromatography Paper Grade A
  • other types of papers are also envisaged.
  • the devices used as illustrative examples in this disclosure were fabricated by printing wax patterns with a Xerox ColorQube Wax printer on Whatman ® Chromatography Paper Grade A. The wax was melted into the paper by placing the paper in an oven at 140°C for 2 minutes.
  • a person skilled in the art would readily recognize that other routes for obtain the desired result may be equally implemented.
  • an electrically conducting material is deposited into the channel. In some embodiments this is done using a pipette. Other techniques such as index printing, gravure coating, mask coating, screen printing are equally conceived as process for this step.
  • the electrically conducting material is deposited as a suspension in water or a solvent.
  • the conducting polymer poly(3,4-ethylenedioxythiophene):poly(styrenesulfonic acid) (PEDOT) suspended in water was deposited on the paper.
  • a 5 wt% dimethylsulfoxide (DMSO) was added to the solution of PEDOT, and this solution was added with a pipette to the channels that were defined by the wax.
  • the excess ink was removed with a tissue and it was allowed to air dry at room temperature (30 minutes).
  • the paper may be heated to expedite evaporation.
  • the solution was added twice to the channel.
  • the PEDOT suspension in water wicked into the entire channel, which was defined by the hydrophobic barrier formed by the wax printing.
  • the PEDOT coated the cellulose fiber, and importantly, it formed a conducting path that extended across the thickness of the sheet of paper rather than localizing on the surface of paper. These are shown in FIGS. 2B, 2C and 2D.
  • PEDOT electrowetting-on-dielectric
  • the PEDOT would spread unevenly across the paper by capillary wicking, and would not form a well- defined conducting path.
  • PEDOT was selected because it is highly conducting (>1000 S/cm), water dispersible, and stable in ambient conditions. It forms thin films that are resilient to bending and stretching.
  • it is equally possible to use other electrically conducting materials.
  • nanoparticulate carbon conducting polymers, metallic dust, and metallic nanoparticles.
  • the patterned actuators were cut, and a layer of Scotch® tape (40 ⁇ thick) was attached to obtain the HEPA. (FIG. 2A). This tape was unaffected by moisture and heat (at least up to 100°C), and acted as the strain-limiting layer to direct the movement.
  • FIG.3A shows the infrared (IR) thermal images demonstrating uniform distribution of heat across the surface of the conducting path, and established that a power (P) of 800 mWcm "2 was needed to reach a temperature of 100°C.
  • P power
  • Thermal images were acquired using a FLIR T600- Series infrared imaging camera. The temperature of 100°C was selected since it is slightly above the boiling point of water.
  • the sheet resistance (R) of PEDOT/paper 800 ⁇ 200 ⁇ / S q) was measured. From these, the operating voltage (V) per area of the HEPA (28
  • t is the thickness
  • E is the Young's modulus, for the paper layer tj, Ej), and the tape layer (t 2 , E 2 ).
  • This result is analogous to a bi-layered beam under thermal expansion, but instead of a thermal strain, this model uses the hygroexpansive strain (£h) defined as the ratio between the changes in length to initial length as a function of moisture content (mc).
  • £h is a linear, and reversible, function of the moisture content described by Equation (2) where ⁇ is defined as the hygroexpansion coefficient, and hence say is the change in the gravimetric moisture content.
  • FIGS. 4A-4F To study the influence of RH on the motion of bending, and on the range of actuation, a pre-curved HEPA was used as shown in FIGS. 4A-4F.
  • power (1 W) moisture evaporated from the paper layer, the HEPA moved down, and an extra paper section (attached to the end of the actuator) contacted and absorbed a droplet of a solution of a blue dye, as shown in FIG. 4B.
  • FIG. 5A shows a pre-curved HEPA that acts as an optical shutter.
  • the HEPA in this example was designed to have an almost semi-circular shape, with an extra paper section that forms a shutter.
  • the HEPA with the shutter was mounted onto a backlit table, as shown in FIG. 5A.
  • the shutter covered the hole and blocked the light.
  • the electricity flow was turned on, the shutter moved, uncovered the hole, and allowed the light to pass through, as illustrated in FIG. 5C.
  • MATLAB® was used for calculating the light intensity from each frame of a video from the optical shutter. The intensity was calculated as the average gray-scale intensity of pixels
  • FIG. 7B shows time-lapse photographs of the linear HEPA that was creased in an accordion-shape. The difference between these two designs was the position of the tape.
  • the angular motion of each crease is in the same direction, which resulted in curving (FIG. 7A).
  • the cumulative angular motion resulted in linear actuation (FIG. 7B), which is an essential motion in many mechanical machines.
  • a central element of the HEP As is the porous conducting polymer path (used to provide electrothermal heating) that is fabricated by printing, and is embedded within the paper.
  • the properties of the conducting path give the HEP As at least four advantages: (i) They are lightweight, inexpensive, and biodegradable, (ii) They are easy to fabricate using a commercial printer, (iii) They are resistant to bending and scratching, because the element that provides electromechanical work is embedded within the paper. These features offer the possibility of designing complex folded structures, (iv) They can actuate many times without showing signs of degradation of performance.
  • HEP As are similar to other paper-based actuators, in that they have the disadvantage that their initial state is influenced by the relative humidity of the environment. Unlike most other paper-based actuators, however, their final state is not affected by relative humidity.
  • FIG. 8A is a schematic diagram of an embodiment of a fabrication procedure for making an electronic pattern.
  • FIGS. 8B-8D are images of the printed structures with top views (top) and cross sections (bottom).
  • FIG. 8B shows the formation of fluidic channels from printing of a first hydrophobic barrier. The printing was performed using techniques similar to the one described above.
  • a first hydrophobic barrier is formed using a yellow wax.
  • a conducting liquid may be disposed in the channels formed above.
  • FIG. 8C shows the embodiment where two different conducting inks, PEDOT (gray) and MWNT (black) have been patterned in different parts of the channels formed in the cellulose matrix.
  • the PEDOT ink was prepared in a manner similar to the one described above.
  • the carbon ink was prepared by mixing MWNT powder (5 g/L) with dissolved carboxymethylcellulose in de-ionized water (2.5 g/L). The mixture was ultra- sonicated with a tapered microtip for 15 minutes using a Branson sonifier 340 with an output power of 400W. The sonicated ink was purified by centrifuging at 4500 rpm for 30 minutes and then decanted.
  • the carbon nanotubes used were MWNTs (>95% carbon), obtained from Sigma Aldrich (product of Southwest Nanotechnology).
  • Carboxymethyl cellulose, sodium salt (M.W. 250,000) was procured from Acros Organics.
  • the ink was allowed to dry through evaporation at room temperature for about 30 minutes. Heating the paper to expedite evaporation is also envisaged.
  • the channels may be treated with a silane solution to improve the fluidic properties.
  • the fluidic property may be enhanced by the spontaneous wicking of the conducting parts in the channels formed by the
  • FIG. 8C shows that both of the conductors penetrate the full thickness of the paper. Due to the penetration of the full thickness of paper, the connection of points on opposite sides of the paper is facilitated, so that complex 3D circuits can be fabricated by stacking several sheets of paper, as shown in some embodiments described later in this disclosure.
  • the electrical resistance of the dry PEDOT and MWNT conductors was measured on patterned lines with a width of 4mm, and with lengths from 1cm up to 15 cm.
  • the resistance per square area of the PEDOT was 280 ⁇ / ⁇ ( ⁇ 11%), and MWNT printed lines 500 ⁇ / ⁇ .
  • another layer of hydrophobic barrier can be printed on top of the areas of the cellulose matrix where the first hydrophobic barrier, such as a yellow wax, was deposited and/or over the areas where the electrically conducting material as deposited inside the channels formed by the deposition of the first hydrophobic barrier. This is shown as the green wax in FIG. 8D.
  • FIG. 8E shows a schematic diagram, and images (top and side view) of a water droplet placed on a printed electronic pattern shown in FIG. 8D.
  • the contact angle of a 50 ⁇ . water droplet on top of a PEDOT conductor that was fabricated with a second wax-printing step shows that the structure is hydrophobic after ( ⁇ ⁇ ⁇ 2 ° > 90°).
  • a 50 ⁇ . water droplet was placed on top of electronic conductors for both PEDOT and MWNT.
  • the resistance of PEDOT decreased slightly ⁇ 4%, and the resistance for the carbon ink increased by ⁇ 5%, 10 minutes after the drop was applied, as shown in FIG. 8G.
  • FIG. 8G shows a schematic diagram, and images (top and side view) of a water droplet placed on a printed electronic pattern shown in FIG. 8D.
  • the contact angle of a 50 ⁇ . water droplet on top of a PEDOT conductor that was fabricated with a second wax-printing step shows that the structure is hydrophobic after ( ⁇
  • FIG. 8G shows the relative resistance measured across electronic structures on paper with a water droplet on top (see the structure in figure FIG. 8E) for an electronic pattern with MWNT (solid line) and PEDOT (dashed line).
  • MWNT solid line
  • PEDOT dashed line
  • FIG. 8F shows schematics of a 2 layer paper device showing 3D wicking in electrofluidic structures (top) and time-lapse photos of same electrofluidic 3D assemblies, showing transport of water through the top and bottom paper layers in carbon printed
  • the surface of the inks are hydrophilic, so the combination of open pores and hydrophilicity implies that water can spontaneously wick the electrical conductors, thus forming both electronic and fluidic (“electrofluidic") conductors.
  • the electrofluidic conductors can also be stacked just like conventional paper microfluidic patterns. Stacking and spontaneous wicking was demonstrated in FIG. 8F.
  • FIG. 8F shows a two-layer paper structure, with MWNT electrofluidic conductor. By placing a water droplet at the top of on one of the circular shapes, spontaneous wicking allowed the fluid to move from the top layer through the conductor and down to the bottom layer, then continued across the conducting line to the other circular shape and moved upwards to the first layer again.
  • a method to fabricate a conductor in the co-fabrication process includes a second step of wax printing. In the regions where the second wax intersects with the electrofluidic patterns, see FIGS. 8D and 8E, the wax melted into and around the cellulose matrix covered by the conductors, upon which the surface of the conductors became hydrophobic turning the intersecting regions into purely electrical conductors.
  • PCB three-layer electronic paper circuit board
  • FIGS. 9A and 9B show a printed multi-layer paper circuit board.
  • FIG. 9A on the left, shows a schematic diagram of a circuit board assembled by folding and spontaneous wicking of conducting polymer ink. The completed folded structure is shown on the right in FIG. 9A.
  • FIG. 9B shows an image of a printed device before folding
  • FIG. 9C shows top view photos of the circuit board with mounted LEDs.
  • the upper LED is powered through the two lines in the bottom layer connected to the top layer through vias and, in the right side of FIG. 9C, the righthand LED is powered through the two top lines.
  • the paper PCB was fabricated by wax printing the three-layer design on a single sheet of paper, and then folded and glued the three layers into a single multi-layer device. As shown in FIG. 9A, the folding procedure automatically aligned the structures for correct positioning of the vias. As an alternative method, the three folded sections could be printed separately on different sheets of paper and stacked on top of each other to attain a similar functioning structure. Variations in steps of manufacturing and sequence of operations are conceived and envisaged within the scope of this disclosure.
  • the design consisted of two parallel lines on the top layer, and two parallel lines in the third layer crossing the lines in the first.
  • the middle and top layer contained quadratic shaped openings that were positioned to connect to the end of the lines in the third layer and thus acted as electronic vias.
  • An electrically conductive material such as PEDOT ink or a carbon ink, can then be added in the fluidic patterns and filled the paper structure by wicking all the three layers simultaneously.
  • PEDOT ink was used for this purpose.
  • a continuous conducting assembly was formed both in-plane and through-plane (i.e., between the paper layers).
  • two light emitting diodes were mounted to the ends of the wires, and by applying potential between the two electrodes at the top layer, the LED could be powered as seen in FIG. 9C, on the left. More interestingly, the other LED could be contacted as well through the electrical vias, as shown in FIG. 9C on the right.
  • FIG. 14A shows the circuit diagram of the device
  • FIGS. 14B and 14C show photos of the paper device.
  • PEDOT ink was used to form the conducting wires in the circuit, as well as for making a resistive heating element and a "pull-up" resistor.
  • Wax printing was used to define the hydrophobic barriers, wherein the resolution of the wax patterns, enable wires with a minimum feature size of around 1mm, which was small enough for the mounting of standard surface mounted (SMD) components such as the diode and the transistor.
  • SMD standard surface mounted
  • the low resistance of the wires allowed interconnection between the components in the circuit.
  • the components can be mounted on the paper by using a conductive glue which connects the legs of the SMD component to the conducting part of the paper wire.
  • the device was folded in the middle to form a two-layer structure where the resistive heater and the fluidic channel were brought into contact (see FIG. 14B).
  • the ability to fold the paper circuit is possible because of an insensitivity of the wires to folding.
  • FIG. 14D shows the paper device of FIG. 14B when it is powered.
  • the microprocessor is programmed to detect the presence of a liquid inside a paper microfluidic channel. Once a liquid is detected, the microprocessor powers the resistive heater, which is in contact with the liquid, and executes a programmed sequence of heating cycles (80 C°, 60 C°, 40 C°, 20 C°).
  • FIG. 14D on the right, shows time-lapse infrared heat images of the resistive heater.
  • the method of making an electrochemical sensor includes providing any of the devices disclosed above, wherein the device further includes a first region of the porous channel in the cellulose matrix that is configured to form a working electrode; a second region of the porous channels in the cellulose matrix that is configured to form a separator; and a third region of the porous channel in the cellulose matrix that is configured to form a counter electrode.
  • a reference electrode is also provided. Additionally, the first region, the second region, the third region and the reference electrode are in electrochemical contact with one another.
  • FIG. 10A An electrochemical sensor that includes three layers of stacked paper, according to some embodiments, is shown in FIG. 10A.
  • a separator is placed between two circularly shaped electrofluidic electrodes (the 2D print area of the circle is 31 mm 2 ).
  • the 2D print area of the circle is 31 mm 2 .
  • Each electrode is in turn connected to printed conductors that are contacted with metallic clips and connected to electrical measurement instrument, as shown in FIG. 10B.
  • a reference electrode is also included.
  • a Ag/AgCl ink may be printed partly into the separator layer to act as a reference electrode.
  • the current discharge comes mainly from the formation of a double layer, and the capacitance of the device was calculated from the discharge curves to be 17 ⁇ /mm 2 .
  • the calculations for the capacitance for the paper electrodes was done by numerical integration of the area of the discharge curve vs. time to obtain the total charge. The charge was divided by DC voltage (0.5 V) and the print area of the electrodes to get a capacitance/area value.
  • a theoretical value of the maximum double layer capacitance was taken to be 0.2 ⁇ /cm 2 from literature values assuming a mercury electrode at 0.5V in 0.1 M salt solution (close to lx PBS).
  • the electrical characterization was made using Keithley 2400, and data acquisition using GPBIB and MATLAB.
  • the ratio between the ideal 2D capacitor and the measured capacitor of the MWNT electrofluidic structure was estimated to 85. This means that the electrical area of the porous electrodes is 85 times larger than its corresponding projected "footprint" area. This value is close to the actual ratio between the specific surface area of the bulk paper and its corresponding 2D area (between 90-100 for Whatman grade 1). These estimates therefore suggest that the conducting paper electrodes are indeed active and are covering the majority of the bulk surface area of the paper.
  • electrofluidic structures have electrochemically active surface area close to the surface area of the paper. It can be inferred from these observations that the electrofluidic structures consist of thin layers of the conductor surrounding the majority of paper fibers, and that the layer is electrically connected (through percolated networks) even when filled with a liquid.
  • electrofluidic structures did not degrade considerably over time, when filled with a liquid, neither due to dissolution, nor structural changes.
  • a method for electrochemical analysis using the above described electrochemical sensor includes further providing a loading electrolyte that enters the porous channels of the first region, the second region and the third region to produce a first interaction with the electrically conducting material disposed therein; wherein, said first interaction produces a baseline electrochemical signal; performing an electrochemical measurement to measure the baseline electrochemical signal; providing an analyte sample that enters the porous channels of the working electrode to produce a second electrochemical signal; analyzing the second electrochemical signal and comparing it with the baseline electrochemical signal to gather information regarding the analyte.
  • said measuring an electrochemical signal includes impedance measurement, current measurement or measurement of voltage.
  • the electrochemical measurement is selected from the group consisting of amperometry, biamperometry, stripping voltammetry, differential pulse voltammetry, cyclic voltammetry, coulometry, chronoamperometry, and potentiometry.
  • the electrochemical measurement is chronoamperometry and the analyte includes glucose, cholesterol, uric acid, lactate, blood gases, DNA, hemoglobin, nitric oxide, and blood ketones.
  • measuring an electrochemical signal comprises anodic stripping voltammetry.
  • FIG. IOC shows the chronoamperometry for ferrocyanide in lxPBS (error bars calculated based on measurement of 3 different devices); and the diagonal line shows the theoretical value of the total amounts of charge per analyte.
  • FIG. IOC (inset) shows the redox reaction of potassium ferri/ferrocyanide measured by cyclic voltammetry (CV) using the paper electrochemical sensor with MWNT electrodes. The anodic peak potential was seen at around 0.3 V, which is in agreement with the values measures on planar carbon electrodes with a Ag/AgCl reference electrodes. Due to the high surface area, the CV curves were measured at lower scan rates (5 mV/s).
  • the measurement procedure can be as follows: 1) T he vertical flow device was filled with 30 ⁇ _, of a loading electrolyte (1M KC1 buffer), whereupon the electrodes and the separator were filled and the reference electrode also connected to this electrolyte. This resulted in a relatively large double layer capacitive discharge current due to the large surface area of the electrodes.
  • FIG. IOC shows the measured charge as a function of the amount of ferrocyanide. The relationship is linear over 2 orders of magnitude and is sensitive below ImM. The red line shows the theoretical value of the total charge as a function of the amount of ferrocyanide and follows the measured values. This indicates that all the electroactive ferrocyanide species are consumed in the potentiometric measurement, so the concentration can be directly estimated without calibration.
  • the ability to detect concentrations of a mediator was used for demonstrating a glucose sensor with a ferrocyanide mediator.
  • the analysis of glucose was performed by adding a solution (250 U/mL glucose oxidase, 500mM potassium ferricyanide in 1 M KC1 in PBS buffer pH 7.0) to the device. A DC potential of 0.8 V was then applied to the device, and after the discharge of the double layer, different concentrations of glucose were added in small amounts ⁇ 2 iL). The added glucose was oxidized by the glucose oxidase to gluconic acid, which then reduced ferricyanide to ferrocyanide, and the total concentration of the produced ferrocyanide was measured as previously.
  • FIG. 10D shows the chronoamperometry for a glucose assay (error bars extracted from 3 devices) and the diagonal line represents a linear fit.
  • the procedure for performing the glucose assay included 250 U/ml Gox in pH 7.0 PBS buffer 1M KC1 and 600 mM Ferricyanide was added in 30uL to the electrode. A DC potentiometric was applied and after 10 minutes of discharge and equilibration time, the glucose solutions were added on the top working electrode at 2uL per concentration. The measurements were made using an Autolab device. A constant potential of +0.8V (against the Ag/AgCl built into the paper device) was used and measurements were made using an Autolab device.
  • FIG. 10D shows the measured total charge vs. the glucose concentration in a range of 2.7-11.1 mM (which is a relevant range for the glucose in human blood).
  • the PEDOT anodes were made by adding a few drops of 50 mg/ml of branched polyenimine (PEI) to the FE paper, followed by drying.
  • PEI branched polyenimine
  • the branched polyethylenimine PEI (60 kDa) was procured from Sigma Aldrich. Electrical characterization was conducted using Keithley 2400.
  • FIG. 12A shows a schematic diagram of the assembly of a printed paper battery using folding, according to some embodiments.
  • FIGS. 12B-12D show images of a fully printed device that contains six serial connected batteries.
  • FIG. 12B shows the structure before folding
  • FIG. 12C shows the structure during folding
  • FIG. 12D shows the folded structure.
  • the batteries are connected to an LED and a paper switch button, which can be in an off-state (left) or an on-state (right), as shown in FIG. 12D.
  • FIG. 12 E shows the equivalent circuit of the device shown in FIG. 12D.
  • the printed single sheet could be folded into a final battery structure according to the schematics shown in FIG. 12A.
  • the structure may be assembled using stacks of appropriately printed papers and making the necessary
  • PEDOT has different reduction states. Thus, it can act both as anode or cathode in a battery.
  • a battery which is charged in its initial dry state is shown. The charging was done by adding a cationic polymer PEI, to segments the conducting paper, where PEI reduced PEDOT to act as anode.
  • the reduced PEDOT has a darker color as can be seen from photos in FIG. 12B.
  • FIG. 12D shows the edge of the paper, as shown in FIG. 12D, and corresponding equivalent circuit diagram shown in FIG. 12E.
  • the electrolyte 1M NaCl
  • FIG. 12D shows the constant current ( ⁇ ) discharge curve of the 6 serial connected batteries similar to the one shown in FIG. 12.
  • the initial voltage was 2.5V corresponding to the additive voltage of each individual battery element (around 0.5 V).
  • a full discharge curve of the battery setup at 5 ⁇ constant current showed a decreasing voltage from 2.5 V down to OV over the course of around one hour, with a peak power of 12.5 ⁇ and an energy density of ⁇ 6 ⁇ 1 ⁇ .

Abstract

Sous un aspect, l'invention concerne un dispositif comprenant un substrat comprenant une matrice de cellulose qui forme une structure poreuse interconnectée, une barrière hydrophobe disposée à travers l'épaisseur du substrat afin de définir au moins un canal poreux à l'intérieur du volume de la matrice de cellulose, et un matériau électriquement conducteur. Le matériau électriquement conducteur est disposé à l'intérieur du volume du canal poreux de façon à revêtir au moins une partie de la matrice de cellulose à l'intérieur de celui-ci. Un procédé de fabrication et d'utilisation d'actionneurs, de capteurs électrochimiques et de batteries au moyen du dispositif est également décrit.
PCT/US2016/050133 2015-09-02 2016-09-02 Cofabrication de composants électroniques et microfluidiques de papier WO2017040947A1 (fr)

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US11066296B1 (en) 2018-08-21 2021-07-20 Iowa State University Research Foundation, Inc. Methods, apparatus, and systems for fabricating solution-based conductive 2D and 3D electronic circuits
US11926524B1 (en) 2018-08-21 2024-03-12 Iowa State University Research Foundation, Inc. Methods, apparatus, and systems for fabricating solution-based conductive 2D and 3D electronic circuits
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