WO2017002051A1 - Dispositif exhaleur d'oxyde nitrique spécialement destiné à réduire l'absorption et la production d'oxyde nitrique en excès dans la cavité nasale et les sinus paranasaux et supprimer des maladies neuropsychiatriques et respiratoires - Google Patents

Dispositif exhaleur d'oxyde nitrique spécialement destiné à réduire l'absorption et la production d'oxyde nitrique en excès dans la cavité nasale et les sinus paranasaux et supprimer des maladies neuropsychiatriques et respiratoires Download PDF

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Publication number
WO2017002051A1
WO2017002051A1 PCT/IB2016/053912 IB2016053912W WO2017002051A1 WO 2017002051 A1 WO2017002051 A1 WO 2017002051A1 IB 2016053912 W IB2016053912 W IB 2016053912W WO 2017002051 A1 WO2017002051 A1 WO 2017002051A1
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WIPO (PCT)
Prior art keywords
nasal
air
sinus
nitric oxide
neuropsychiatric
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Application number
PCT/IB2016/053912
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English (en)
Inventor
Rathnasiri BANDARA
Original Assignee
Bandara Rathnasiri
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Publication date
Application filed by Bandara Rathnasiri filed Critical Bandara Rathnasiri
Publication of WO2017002051A1 publication Critical patent/WO2017002051A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/08—Inhaling devices inserted into the nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/0085—Devices for generating hot or cold treatment fluids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/60—Containers for suction drainage, adapted to be used with an external suction source
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0057—Pumps therefor
    • A61M16/0066—Blowers or centrifugal pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0666—Nasal cannulas or tubing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1005—Preparation of respiratory gases or vapours with O2 features or with parameter measurement
    • A61M16/1015—Preparation of respiratory gases or vapours with O2 features or with parameter measurement using a gas flush valve, e.g. oxygen flush valve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/1075—Preparation of respiratory gases or vapours by influencing the temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M21/00—Other devices or methods to cause a change in the state of consciousness; Devices for producing or ending sleep by mechanical, optical, or acoustical means, e.g. for hypnosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0001—Body part
    • A61F2007/0002—Head or parts thereof
    • A61F2007/0006—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0059—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
    • A61F2007/006—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit of gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/007—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating
    • A61F2007/0071—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a resistor, e.g. near the spot to be heated
    • A61F2007/0072—Heating or cooling appliances for medical or therapeutic treatment of the human body characterised by electric heating using a resistor, e.g. near the spot to be heated remote from the spot to be heated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0086—Heating or cooling appliances for medical or therapeutic treatment of the human body with a thermostat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/06—Respiratory or anaesthetic masks
    • A61M16/0683—Holding devices therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10—Preparation of respiratory gases or vapours
    • A61M16/105—Filters
    • A61M16/106—Filters in a path
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/20—Valves specially adapted to medical respiratory devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0208—Oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0266—Nitrogen (N)
    • A61M2202/0275—Nitric oxide [NO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3653—General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/75—General characteristics of the apparatus with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated

Abstract

La présente invention concerne un dispositif spécialement destiné à empêcher l'absorption et la production d'oxyde nitrique nasal et sinusal dans les sinus paranasaux et supprimer des troubles neuropsychiatriques et des maladies des voies respiratoires. Ce dispositif comprend un boîtier, une unité d'alimentation en énergie, un ventilateur de soufflage, en communication avec une sortie normale, et une partie de production de chaleur. Il est conçu comme une unité qui extrait et souffle de l'air pendant quelques minutes à la fois et, de plus, souffle de l'air chaud sur la peau du visage, du nez ou périorale afin de maintenir éveillé ou d'augmenter réellement le tonus sympathique de la muqueuse nasale et sinusale. Ce dispositif peut notamment être utilisé pour réduire la somnolence pendant des occasions ou des événements importants, tels que pendant la conduite, l'étude, l'écoute de conférences, les services de sécurité et le travail sur machine. Le dispositif proposé convient de préférence pour le traitement et pour le diagnostic de troubles de nature neuropsychiatrique liés à des phénomènes d'oxyde nitrique hypoxique sinusal, tels que migraine, vertiges, narcolepsie, somnolence, stress psychologique (par exemple paresse, léthargie, peur), et d'impulsions ou d'humeurs impulsives (par exemple colère, tristesse, dirigées vers soi-même ou vers les autres), et l'amélioration de la santé neurologique et respiratoire. Le dispositif peut en outre être utilisé pour diminuer la co-morbidité d'autres maladies avec la migraine ou la SHNOP, par exemple des troubles endocriniens, des maladies cardiaques, des maladies de la peau, des sinus, etc.
PCT/IB2016/053912 2015-06-30 2016-06-30 Dispositif exhaleur d'oxyde nitrique spécialement destiné à réduire l'absorption et la production d'oxyde nitrique en excès dans la cavité nasale et les sinus paranasaux et supprimer des maladies neuropsychiatriques et respiratoires WO2017002051A1 (fr)

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LK11829515 2015-06-30
LKLK/P/1/18295 2015-06-30

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WO2017002051A1 true WO2017002051A1 (fr) 2017-01-05

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019043681A1 (fr) * 2017-09-04 2019-03-07 Jerasi Meir Appareil amélioré pour une respiration améliorée par les narines
CN109663205A (zh) * 2019-02-15 2019-04-23 云南中医学院 一种鼻腔缓释给药装置
DE102019114682B3 (de) 2019-05-31 2020-08-06 Philipp Steinau Vorrichtung und ein Verfahren zum Erzeugen oder Erhöhen von nasaler Luftzirkulation zur verbesserten Geruchs- und Geschmacksempfindung

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US4226233A (en) 1978-10-10 1980-10-07 Longevity Products, Inc. Respirators
GB2196858A (en) 1986-09-30 1988-05-11 Roland Richard Gibson Respiratory apparatus
US5018517A (en) 1987-10-22 1991-05-28 Claude Liardet Expiration-resisting apparatus designed for improving pulmonary ventilation
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FR2758267A1 (fr) * 1997-01-16 1998-07-17 Raymond Cohen Inhalateur de produits medicamenteux emballes en doses individuelles et fonctionnant sans adjonction de liquide chaud
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WO2016075193A1 (fr) * 2014-11-11 2016-05-19 Breas Medical Ab Dispositif pour fournir une pression de gaz inspiratoire à un patient

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US4054134A (en) 1975-09-15 1977-10-18 Kritzer Richard W Respirators
US4226233A (en) 1978-10-10 1980-10-07 Longevity Products, Inc. Respirators
US5038769A (en) * 1983-06-29 1991-08-13 Krauser Robert S Method and apparatus for treating ailments
GB2196858A (en) 1986-09-30 1988-05-11 Roland Richard Gibson Respiratory apparatus
US5018517A (en) 1987-10-22 1991-05-28 Claude Liardet Expiration-resisting apparatus designed for improving pulmonary ventilation
US5569122A (en) 1994-05-11 1996-10-29 Cegla; Ulrich Therapeutic device for improving breathing
FR2758267A1 (fr) * 1997-01-16 1998-07-17 Raymond Cohen Inhalateur de produits medicamenteux emballes en doses individuelles et fonctionnant sans adjonction de liquide chaud
US20050150501A1 (en) * 2002-05-17 2005-07-14 Christian Opitz Therapy device for local treatment of colds
WO2003105937A1 (fr) 2002-06-14 2003-12-24 Aerocrine Ab Dispositif et procede de ventilation des voies aeriennes superieures chez un etre humain
US20060260609A1 (en) * 2005-05-20 2006-11-23 Johann Bruening Therapy device for the specifically local treatment of illnesses transmitted by droplet infection, in particular colds
WO2016075193A1 (fr) * 2014-11-11 2016-05-19 Breas Medical Ab Dispositif pour fournir une pression de gaz inspiratoire à un patient

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ICHINOSE M; SUGIURA H; YAMAGATA S; KOARAI S; SHIRATO K.: "Increase in reactive nitrogen species production in chronic obstructivepulmonary disease airways", AM J RESPIRCRIT CARE MED, vol. 162, 2000, pages 701 - 706, XP055197130, DOI: doi:10.1164/ajrccm.162.2.9908132
LUNDBERG JO.: "Nitric oxide and paranasal sinuses", ANAT REC (HOBOKEN, vol. 291, no. 11, 2008, pages 149 - 84
LUNDBERG JON; FARKAS-SZALLASI T; WEITZBERG E ET AL.: "High nitric oxide production in human paranasal sinuses", MEDICINE, vol. 1, 1995, pages 370 - 3
LUNDBERG JON; FARKAS-SZALLASI T; WEITZBERG E ET AL.: "High nitric oxide production in human paranasal sinuses", NATURE MED, vol. 1, 1995, pages 370 - 373
M. S.M. RATHNASIRIBANDARA.MIGRAINE: "Migraine and neurological disorders disorder explained by Sinus hypoxic nitric oxide theory", J NEUROLDISORD, vol. 2, 2014, pages 5
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WEITZBERG EL; LUNDBERG JO: "Humming greatly increases nasal nitric oxide", AM J RESPIRCRIT CARE MED., vol. 166, no. 2, 15 July 2002 (2002-07-15), pages 144 - 5, XP002962503, DOI: doi:10.1164/rccm.200202-138BC

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019043681A1 (fr) * 2017-09-04 2019-03-07 Jerasi Meir Appareil amélioré pour une respiration améliorée par les narines
US20200215281A1 (en) * 2017-09-04 2020-07-09 Meir JERASI Improved apparatus for enhanced nostril breathing
US11759587B2 (en) * 2017-09-04 2023-09-19 Meir JERASI Apparatus for enhanced nostril breathing
CN109663205A (zh) * 2019-02-15 2019-04-23 云南中医学院 一种鼻腔缓释给药装置
DE102019114682B3 (de) 2019-05-31 2020-08-06 Philipp Steinau Vorrichtung und ein Verfahren zum Erzeugen oder Erhöhen von nasaler Luftzirkulation zur verbesserten Geruchs- und Geschmacksempfindung

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