WO2016203212A2 - Système optique - Google Patents

Système optique Download PDF

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Publication number
WO2016203212A2
WO2016203212A2 PCT/GB2016/051754 GB2016051754W WO2016203212A2 WO 2016203212 A2 WO2016203212 A2 WO 2016203212A2 GB 2016051754 W GB2016051754 W GB 2016051754W WO 2016203212 A2 WO2016203212 A2 WO 2016203212A2
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WO
WIPO (PCT)
Prior art keywords
eye
light
illumination
measurement
region
Prior art date
Application number
PCT/GB2016/051754
Other languages
English (en)
Other versions
WO2016203212A3 (fr
Inventor
Neil Griffin
Nick WOODER
Luis Diaz-Santana
Roger Clarke
Original Assignee
The Technology Partnership Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Technology Partnership Plc filed Critical The Technology Partnership Plc
Publication of WO2016203212A2 publication Critical patent/WO2016203212A2/fr
Publication of WO2016203212A3 publication Critical patent/WO2016203212A3/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/113—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining or recording eye movement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/11—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring interpupillary distance or diameter of pupils
    • A61B3/112—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for measuring interpupillary distance or diameter of pupils for measuring diameter of pupils
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/0093—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00 with means for monitoring data relating to the user, e.g. head-tracking, eye-tracking
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00—Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/10—Beam splitting or combining systems
    • G02B27/108—Beam splitting or combining systems for sampling a portion of a beam or combining a small beam in a larger one, e.g. wherein the area ratio or power ratio of the divided beams significantly differs from unity, without spectral selectivity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6814—Head
    • A61B5/6821—Eye

Definitions

  • sensing and computing technologies has enabled an increasing range of technologies and products aimed at providing this functionality built into a wearable form.
  • One popular example is the trend for so- called smart glasses that provide a digital display presented in front of the eye in a product that is worn in a similar manner to a pair of spectacles.
  • Another example is the wide range of health and fitness monitoring devices that are typically in the form of a chest band or bracelet, and which sense heart rate and other parameters using sensors that contact the skin.
  • Eye tracking which monitors the gaze angle of the eye, and is used for example in studies for determining how the subject looks at their environment.
  • Sensors for these devices are typically cameras embedded in the frame of a bulky head worn device, which look obliquely toward the eye to avoid obscuring the wearer's field of view. This viewing position demands that the camera is placed in a forward position relative to the eye, making the device bulky, and limits the ability to measure many of the properties of the eye due to the oblique angle.
  • the ability to optically access the eye at on-axis or near on-axis angles has several advantages. Firstly, the access to the retina near to the fovea is possible only through an on-axis view. Secondly, the view of the pupil and iris is undistorted such that eye monitoring and / or imaging of the eye is easier and more accurate. Thirdly, light illuminating the eye is more easily redirected back along a similar optical path to the appropriate sensors with an on-axis incidence angle, leading to a more compact implementation.
  • An ideal device for monitoring a range of parameters from the eye would allow the measurement to be made from a direction in front of the eye while not causing the field of view of the wearer to be blocked and at the same time allowing the sensors to be positioned away from the front of the face such that the device can be more discrete and compact in a form factor similar to that of normal spectacles.
  • Such a device would increase the range of parameters that could be measured and would allow the device to be worn for extended periods to increase the value of the device for monitoring changes over time in the state of the parameters being measured.
  • the present invention relates to an unobtrusive head worn optical platform for measuring and monitoring physiological and other parameters measured in on or near the eye while enabling the user to use the optical platform without significantly obscuring or restricting the field of view.
  • the measurements might be taken from the region inside of the eye, from the front of the eye, or from the region of skin or mucous surrounding the eye. Examples include the cornea, eye lid, anterior chamber, retina, iris, sclera, choroid, and the lacrimal area.
  • the use of a beam combining element allows imaging or sensing of the eye by optical means on or near to the viewing axis of the eye, thereby making the optical measurement simpler and more accurate.
  • Figure 1 shows a schematic overview of a system according to the invention, including the various light paths;
  • Figure 2 shows an example beam combiner using an embedded grating for use in the system of the invention. Description of invention
  • the central feature of the present invention is a beam combiner element that allows the measurements to be performed near to the viewing axis of the eye without obscuring the view observed by the eye.
  • the beam combiner element functions by allowing multiple optical paths to pass as depicted in Figure 1.
  • the beam combiner 1 is positioned in front of the eye 2.
  • the beam combiner is partially transparent such that the eye can see the external scene 3 via light path 4, and can be seen by an outside observer 5 via light path 6 and can receive illumination from external light sources 7 via light path 8, such as daylight or room lights or illumination applied for measurement purposes.
  • the beam combiner is also partially reflecting so that some of the light reflected from the eye is deflected toward a detection system 9 via light path 10.
  • the partial reflection furthermore allows illumination for measurement purposes to be applied via the reflected light path 12 from a light source 1 1 if required. Illumination may also be applied direct from a source 13 via light path 14.
  • An undesirable light path 15 also exists whereby ambient light enters the measurement system 9, interfering with the measurement light.
  • the present invention functions in a similar fashion to many head mounted display technologies except that it is designed to relay optical signals from the eye rather than to the eye. Therefore many of the beam combiner technologies used for HMDs may be equally well applied here, and this invention may even be incorporated into a HMD product to provide both functions.
  • An example beam combiner technology is the embedded grating technology disclosed for display applications by WO201 1124897A1.
  • This uses a partially reflective Fresnel reflector of arbitrary shape to define the reflection of the light, and embeds this reflector within a transparent optical component so that light transmitted by the reflector is not deflected ( Figure 2).
  • the Fresnel surface enables the optical power of the reflector to be largely uncoupled from the shape and orientation of the embedding optic.
  • the technology has particular advantages in that it can be incorporated into a thin lens of arbitrary curved form, such as a spectacle lens or helmet visor, so it can be inconspicuously incorporated into a head worn device.
  • planar lightguides combined with beam turning elements such as diffraction gratings, volume holograms, reflecting or refracting microstructures, scattering materials or structures
  • beamsplitting cubes or prisms including polarising and non-polarising devices, devices employing total internal reflection and devices using metallic or dielectric reflecting layers
  • devices that reflect a free-space light signal including flat or curved reflecting surfaces which may be either uncoated or coated with a partially reflecting layer, or may incorporate diffraction gratings and volume holograms or phase conjugate materials.
  • These technologies achieve the beam combining function through use of a surface that is partially transmitting and partially reflecting. This may be achieved through partial reflectivity by a dielectric interface or dielectric layer or by a thin metallic coating.
  • a dielectric stack of layers may be employed to provide a surface that effectively transmits some wavelengths and effectively reflects other wavelengths.
  • Other coatings and interfaces may be used to provide a surface that differentially transmits or reflects light of different polarisations.
  • a device may also be made to be effectively partially reflecting by being constructed to comprise one or more fully reflecting regions, where the reflecting regions are sufficiently small that they do not fully obscure all the light paths described in Figure 1.
  • the reflecting elements should be small relative to the pupil of the eye such that light paths 4 and 10 can both pass through the pupil at the same angle.
  • One small reflecting element could meet this requirement, but to provide a wider field of view for the detection optics, it is preferred to have a plurality of small reflecting elements in a regular or irregular arrangement separated by transmitting regions, or to have a reflecting surface with transmitting apertures contained within it.
  • the feature size should preferably also be small enough that external observer 5 cannot easily notice the features at typical viewing distances, or they might be concealed behind tinted or reflective layers.
  • the form of the reflecting surfaces is dependent on the requirements of the detection and illumination systems 9 and 11.
  • One example form is for the reflectors to be planar, in which case the detection optics may be quite simple.
  • the reflectors may take a curved form such that they provide an additional optical function to increase the magnification or to increase the light collection capability of the system in order to improve the detection sensitivity.
  • Possible curved forms include spherical, conic, biconic or polynomial, or combinations of these functions, and may also include additional contributions such as tilt, decentre, paraboloid, hyperboloid and Zernike or similar polynomial terms.
  • a curved reflecting surface this may be employed to provide an image of the region of interest in the vicinity of the detection optics.
  • a detector may be positioned at this image location, or further optics may be employed to relay this image to a detection plane.
  • relay optics that correct for aberrations introduced by the reflecting elements.
  • Curved surfaces in the beam combiner may also be used to direct, focus or concentrate illumination light 11.
  • the system is arranged to measure structures near the front of the eye or the surrounding tissue, it is often desirable to detect light from a relatively large area. To achieve this it is preferable that the beam combiner reflector should not have a large positive optical power, as this will reduce the viewing area. Zero power or negative power or small positive power is preferred in this case.
  • the beam combiner element may be positioned in front to the eye in isolation, or it may be combined with lenses of prescription or non-prescription eyeglasses or other eyewear, in which case the beam combiner may be incorporated inside the lens, on either surface of the lens, or part of a separate element placed in front or behind the lens. If placed in front or behind the lens they can be in contact with the lens or there can be a gap between the beam combiner surfaces and the lens.
  • Additional optics may be used for example to improve imaging quality, to improve light collection efficiency or to direct, focus or concentrate illumination light 11.
  • a device including the present invention may comprise a single beam combiner or it may comprise a plurality of beam combiners to allow multiple measurements to be conducted concurrently.
  • the detection system 9 can form an image of the region of interest onto an imaging sensor such as a CCD, CMOS sensor, silicon photomultiplier array, thermographic sensor, or other detector array for further analysis using image processing algorithms.
  • the detection system can direct the light onto a non-imaging sensor such as one or more photodiodes, photodiode arrays, photomultiplier tubes, thermal infrared sensors or spectrometers for further analysis using appropriate signal processing algorithms.
  • a non-imaging sensor may be used to obtain spatially discriminated data by scanning the light source or by applying illumination to different regions at different times.
  • the optical signal detected from the region of interest may be generated by incident light being reflected or scattered from the region of interest. Scattered light may be scattered directly from the surface of interest, or may scatter through the bulk of the tissue before being scattered back.
  • the incident light may be provided by ambient lighting 7 via light path 8 or an illumination source 1 1 or 13 may be directed toward the region of interest via light path 12 or 14.
  • the light may be used without modification or it may be controlled to achieve the desired effects by using additional optical or mechanical elements.
  • environmental light may be filtered to use only certain wavelengths or it may be optically redirected or mechanically masked to ensure illumination of specific tissues only.
  • An active modulator may be used to apply a time variation to the ambient illumination.
  • a system using ambient illumination may be used to record images from which information on shape, size, colour, position and time variation of these properties may be derived.
  • Non imaging measurements possibly using a reference measurement to adjust for the effects of varying illumination, may also be used to measure, for example, colour/spectral properties.
  • the illumination may be applied via the beam combiner (light path 12) or directly (light path 14), depending on the illumination requirements. Illumination via the beam combiner is particularly advantageous when the illumination is required to be substantially coaxial with the detection path, for example for measuring features inside the eye.
  • the illumination may be of any wavelength range or set of wavelength ranges, including visible and non-visible.
  • this light source may be any convenient source of white light or light of one or more wavelength or wavelength range.
  • illumination might be an LED which is compact and efficient.
  • wavelength of light is important to the measurement, this may be achieved by using illumination of a specific known wavelength, such as an LED or laser, or a broadband light source used in conjunction with a filter. Multiple wavelengths may also be used either simultaneously or sequentially using multiple light sources or a scanned wavelength source. Multiple wavelengths may also be measured using a light source containing multiple wavelengths combined with a wavelength sensitive detection system such as a spectrometer or photodetectors with different wavelength filters.
  • a specific known wavelength such as an LED or laser
  • a broadband light source used in conjunction with a filter.
  • Multiple wavelengths may also be used either simultaneously or sequentially using multiple light sources or a scanned wavelength source. Multiple wavelengths may also be measured using a light source containing multiple wavelengths combined with a wavelength sensitive detection system such as a spectrometer or photodetectors with different wavelength filters.
  • Any illumination system may have a time variation applied to the light source. This may be used to minimise the power consumption by only applying power when needed for a measurement.
  • the measurement may also be synchronised with a modulated source to improve the signal to noise ratio and to reduce background signal using phase sensitive detection or simple image subtraction. Where a high intensity of light is needed for a measurement, a short pulse of light may be applied to avoid damage to the eye or other tissue, or to avoid photobleaching of a dye or fluorescent material. Some measurements may require other specific properties for the illumination and detection systems.
  • a coherent illumination beam may be used for example for holographic imaging or for optical coherence tomography (OCT).
  • Coherent light sources may also be used for laser speckle contrast or laser Doppler contrast measurements.
  • An illumination source with a defined polarisation state may be used for a polarisation measurement such as polarimetry or ellipsometry.
  • a fluorescent measurement may be made using light with a suitable pump wavelength combined with a measurement system that is sensitive to the relevant emission wavelength.
  • the system is arranged to measure structures near the front of the eye or the surrounding tissue, it is simple to apply illumination light from any direction, and specific illumination directions may be chosen to highlight or suppress specular reflections or to enhance contrast of texture of other surface morphology structures.
  • an illumination source providing a spatially variant illumination pattern and incident at an angle oblique to the measurement direction may be used with an imaging system to measure three dimensional shape of a surface or interface.
  • illumination may be provided at angles oblique to the measurement directions to highlight scattering structures.
  • the system is arranged to measure structures of the eye behind the pupil, it is necessary to provide illumination substantially coaxial with the measurement axis. This may be achieved by allowing the substantially coincident light paths 10 and 12 to be split by a beam splitter within the measurement and illumination system.
  • An additional difficulty when measuring internal eye structures is to prevent the measurement signal being overwhelmed by the reflection from the cornea and surrounding external structures of the eye.
  • This reflection may be suppressed by use of polarised illumination light, whereby the measurement system measures only light of the opposite polarisation which has been scattered by the tissue at the region of interest. It may also be suppressed by subtraction of signals measured with multiple wavelengths, whereby the corneal reflection is relatively independent of wavelength while reflection from the features of interest has a strong wavelength dependence.
  • the reflection may also be suppressed by arranging a small offset between the illumination and measurement paths, such that the beam footprint on the surface of the cornea does not overlap for the two paths. Multiple non-overlapping beam paths may be provided where it is expected that the eye may be measured in different positions relative to the optical system. Confocal detection may also be used to selectively detect light reflected from the retina rather than from interfaces at different focal depths.
  • the region of the retina that is accessible to optical measurement may be small due to optical restrictions. This measurement area may be extended by making use of the movement of the eye. As the eye rotates, due to the gaze angle change, the region of the retina imaged by the measurement system changes, and multiple images may be stitched together to provide an image of a larger area.
  • light or another energy source may be used to probe the region of interest, such that the optical signal returned to the detection system 9 is changed by application of the energy source. In this way, some physical property of the tissue may be analysed. Examples of such measurements include the use of light to cause pupil dilation, or a localised temperature rise.
  • a mechanical perturbation may be applied by a physical contact probe or by an air puff or by fluid applied as a jet or droplet or stream of droplets, or by acoustic excitation using a contact or non- contact generator of sound or ultrasound, or using a photoacoustic excitation. Fluids may also be directed onto the region of interest to provide a chemical change, such as application of a fluorescent dye.
  • the region of interest for a measurement may be any optically accessible region in or near the eye. This may include one or more of the following:
  • Exterior structures of the eye for example the cornea, sclera, scleral blood vessels, tear film, conjunctiva, limbus;
  • Areas of skin or tissue surrounding the eye for example the eye lids, meibomian gland region, medial angle, lateral palpebral commissure, superior or inferior palpebral sulcus, lacrimal caruncle, medial canthus;
  • Anterior regions of the eye for example the iris, pupil, inner and posterior cornea, anterior chamber angle, aqueous humour, vitreous body, crystalline lens, ciliary body, suspensory ligaments of the lens, zonules;
  • the vitreous and/or vitreous body of the eye The vitreous and/or vitreous body of the eye;
  • Retinal areas or structures for example the fovea, macula, optics nerve head, lamina cribrosa, retinal blood vessels, choroid, choroidal blood vessels, retinal nerve fibre layer, retinal ganglion cells, other retinal tissues;
  • Foreign bodies located in or near the eye for example a contact lens, intra ocular lens or other implant, or shrapnel or other contaminant located in the eye as a result of misadventure.
  • the system according to the present invention may be incorporated into a head worn device in many ways. Any device or garment that can be attached to the head or near the head, and which can present a suitable beam combiner device and associated optics in front of the eye may be used.
  • Example devices and garments that may be adapted to incorporate this invention include prescription or non-prescription eyeglasses, prescription or non-prescription sunglasses, goggles, helmet, breathing mask, visor, headband, monocle, hat or cap, headphones, audio headset, or an augmented reality / virtual reality / smart glass product.
  • the product will typically also incorporate electronic subsystems to power and control the light source and detection components, to condition detected signals and to store or communicate the data to a remote device.
  • the device may communicate to a medical professional to allow them to monitor the health of a patient's eye. Additional sensors may be included to provide additional information such as temperature, motion, position, lighting conditions, etc.
  • the system will be designed to use the space available within an existing device as far as possible to minimise the extent to which the size of the device needs to be enlarged, while preventing obscuration of the vision.
  • the illumination and detection optics would typically be designed to be located close to the head in the vicinity of the beam combiner optic. For example, they may be positioned alongside the temple, cheek or forehead of the wearer. Most of the electronics components do not need to be positioned close to the optics, so they may be positioned anywhere within the device where space is available.
  • the optics could be located in one arm of the frame, near to the eye being measured, and some or all of the electronics may be conveniently positioned in the other arm of the frame to provide a more balanced form factor.
  • the device can be arranged such that the optical and electronic subsystems fit into the head worn device or garment incorporating the device in such a way that the any required change in shape of the head worn device or garment is small such that it does not adversely affect the function or aesthetic appearance of the device or garment.
  • the aspects of the invention described above may be combined in various ways to provide a measurement system for one or more physiological parameters. The following paragraphs describe some specific example measurements and applications where the system may be used.
  • the invention may be arranged to provide a means of monitoring dry-eye condition. This may be undertaken, for example, via imaging of the meibomian gland regions or via optical chemical analysis of the tear film and surrounding liquid/lipid film where techniques including spectral analysis and fluorescence may provide suitable mechanisms for measurement. Other possible techniques that may be used to monitor tear film distributions include ellipsometry, interferometry, surface profiling with structured light, light scatter measurements and thermal imaging.
  • the invention may be arranged to provide an inexpensive means to monitor eye fatigue or general fatigue. This can be quantified through examination of a range of optically accessible measurements.
  • Simple imaging of the front of the eye may be used to track eye movement and transient and static pupil diameters, and to measure frequency, duration and amplitude of blinks.
  • Colour discrimination either by imaging or by a colour sensitive nonimaging detector, such as a spectrometer, or multiple photodetectors with colour filters, can be used to measure reddening of the sclera or skin around the eye.
  • Tear film monitoring as discussed above may also be employed as an indicator.
  • the invention may be arranged to provide monitoring of features in the cornea, for example to monitor wound healing following an injury or eye surgery (e.g. LASIK/LASEK or IOL implantation).
  • Simple imaging may provide a means to track the healing process. Tear film monitoring as discussed above may also be employed as an indicator. Imaging of features (such as iris patterns) through the healing cornea may provide further information.
  • the invention may be arranged to provide measurement of intra-ocular pressure.
  • An air puff, acoustic or ultrasound waves, a droplet or fluid jet impact or some other mechanical means may be used to mechanically perturb the ocular surface and elicit a mechanical response that can be correlated with the intra-ocular pressure.
  • the perturbation of the ocular surface could be measured by recording the deflection of a light beam using a detector like a photodiode, a quad-cell or detector array, or it could be measured using interferometry techniques such as OCT or time series analysis of images of the eye taken using structured illumination.
  • the invention may be arranged to provide continuous measurement of pulse rate and blood oxygen saturation. These can be measured by monitoring the time variation of reflectance spectra of the near eye tissue, such as the medial angle and angular artery regions, using imaging or non-imaging detectors. It is not necessary to measure a full spectrum, and typically the information can be extracted from as few as two wavelength bands. An inexpensive option is to use the red-green-blue image from a normal colour imaging camera. Where only pulse rate is required, this may be measured from time variance of features such as pupil diameter or scleral blood vessel width.
  • the invention may be arranged to diagnosis of glaucoma through measurement of retinal images or retinal OCT scans.
  • the invention may be arranged to chemically analyse the interior of the eye. This might be used as a proxy for blood chemistry. This may be done by analysing light reflected from internal structures of the eye such that the light path passes through internal regions of the eye. For example, the light might be analysed by infrared absorption spectrometry or polarimetry.

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  • Physics & Mathematics (AREA)
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Abstract

La présente invention a trait à un système qui comprend un dispositif optique porté sur la tête et permettant de contrôler un ou plusieurs paramètres physiologiques à partir d'une région d'intérêt située sur, dans ou à proximité de l'œil d'un utilisateur. Le dispositif comprend un sous-système de mesure positionné sensiblement à l'extérieur du champ de vision d'un utilisateur, et un élément de mélange de faisceaux optiques situé dans le champ de vision, ledit élément laissant passer une partie de la lumière qui arrive sur lui, tandis qu'une seconde partie de la lumière est déviée de telle sorte que le sous-système de mesure puisse accéder optiquement à l'œil par l'intermédiaire de l'élément de mélange de faisceaux optiques.
PCT/GB2016/051754 2015-06-15 2016-06-13 Système optique WO2016203212A2 (fr)

Applications Claiming Priority (2)

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GB1510400.3 2015-06-15
GBGB1510400.3A GB201510400D0 (en) 2015-06-15 2015-06-15 Optical system

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WO2018211082A1 (fr) * 2017-05-18 2018-11-22 Osram Opto Semiconductors Gmbh Système de reconnaissance de l'iris
EP3809187A1 (fr) 2019-10-16 2021-04-21 Seemore S.A. Visiere pour un casque ou un heaume
WO2021130739A1 (fr) 2019-12-25 2021-07-01 Lumus Ltd. Systèmes et procédés optiques d'oculométrie basée sur la réorientation de la lumière de l'œil au moyen d'un agencement optique associé à un élément optique guide de lumière
US11051689B2 (en) 2018-11-02 2021-07-06 International Business Machines Corporation Real-time passive monitoring and assessment of pediatric eye health
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DE102016216611A1 (de) 2016-09-02 2018-03-08 Carl Zeiss Meditec Ag Beleuchtungssystem für die Bestimmung der Topografie der Kornea eines Auges
US11759105B2 (en) 2016-09-02 2023-09-19 Carl Zeiss Meditec Ag Illuminating system for determining the topography of the cornea of an eye
WO2018211082A1 (fr) * 2017-05-18 2018-11-22 Osram Opto Semiconductors Gmbh Système de reconnaissance de l'iris
US11051689B2 (en) 2018-11-02 2021-07-06 International Business Machines Corporation Real-time passive monitoring and assessment of pediatric eye health
EP3809187A1 (fr) 2019-10-16 2021-04-21 Seemore S.A. Visiere pour un casque ou un heaume
WO2021130739A1 (fr) 2019-12-25 2021-07-01 Lumus Ltd. Systèmes et procédés optiques d'oculométrie basée sur la réorientation de la lumière de l'œil au moyen d'un agencement optique associé à un élément optique guide de lumière
CN114787687A (zh) * 2019-12-25 2022-07-22 鲁姆斯有限公司 基于使用与光导光学元件相关联的光学布置对来自眼睛的光的重定向来进行眼睛跟踪的系统和方法
EP4042227A4 (fr) * 2019-12-25 2022-12-14 Lumus Ltd. Systèmes et procédés optiques d'oculométrie basée sur la réorientation de la lumière de l'oeil au moyen d'un agencement optique associé à un élément optique guide de lumière
US12019249B2 (en) 2019-12-25 2024-06-25 Lumus Ltd. Optical systems and methods for eye tracking based on redirecting light from eye using an optical arrangement associated with a light-guide optical element
CN114787687B (zh) * 2019-12-25 2024-07-30 鲁姆斯有限公司 基于使用与光导光学元件相关联的光学布置对来自眼睛的光的重定向来进行眼睛跟踪的系统和方法

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