WO2016168344A8 - Method and system for microbiome-derived characterization, diagnostics and therapeutics for conditions associated with functional features - Google Patents

Method and system for microbiome-derived characterization, diagnostics and therapeutics for conditions associated with functional features Download PDF

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Publication number
WO2016168344A8
WO2016168344A8 PCT/US2016/027349 US2016027349W WO2016168344A8 WO 2016168344 A8 WO2016168344 A8 WO 2016168344A8 US 2016027349 W US2016027349 W US 2016027349W WO 2016168344 A8 WO2016168344 A8 WO 2016168344A8
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WO
WIPO (PCT)
Prior art keywords
microbiome
characterization
therapeutics
diagnostics
functional features
Prior art date
Application number
PCT/US2016/027349
Other languages
French (fr)
Other versions
WO2016168344A1 (en
Inventor
Zachary APTE
Daniel Almonacid
Jessica RICHMAN
Siavosh Rezvan BEHBAHANI
Original Assignee
uBiome, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by uBiome, Inc. filed Critical uBiome, Inc.
Priority to AU2016250096A priority Critical patent/AU2016250096A1/en
Priority to EP16780662.9A priority patent/EP3283650A4/en
Priority to CN201680034379.5A priority patent/CN107849616B/en
Publication of WO2016168344A1 publication Critical patent/WO2016168344A1/en
Publication of WO2016168344A8 publication Critical patent/WO2016168344A8/en
Priority to AU2022203347A priority patent/AU2022203347A1/en

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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/20—Supervised data analysis
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Data Mining & Analysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Theoretical Computer Science (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biotechnology (AREA)
  • Evolutionary Biology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Databases & Information Systems (AREA)
  • Analytical Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Bioethics (AREA)
  • Artificial Intelligence (AREA)
  • Evolutionary Computation (AREA)
  • Genetics & Genomics (AREA)
  • Software Systems (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Primary Health Care (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A method for at least one of characterizing, diagnosing, and treating a condition associated with microbiome-derived functional features in at least a subject, the method comprising: receiving an aggregate set of biological samples from a population of subjects; generating at least one of a microbiome composition dataset and a microbiome functional diversity dataset for the population of subjects; generating a characterization of the condition based upon features extracted from at least one of the microbiome composition dataset and the microbiome functional diversity dataset; based upon the characterization, generating a therapy model configured to correct the condition; and at an output device associated with the subject, promoting a therapy to the subject based upon the characterization and the therapy model.
PCT/US2016/027349 2015-04-13 2016-04-13 Method and system for microbiome-derived characterization, diaganostics and therapeutics for conditions associated with functional features WO2016168344A1 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2016250096A AU2016250096A1 (en) 2015-04-13 2016-04-13 Method and system for microbiome-derived characterization, diagnostics and therapeutics for conditions associated with functional features
EP16780662.9A EP3283650A4 (en) 2015-04-13 2016-04-13 Method and system for microbiome-derived characterization, diagnostics and therapeutics for conditions associated with functional features
CN201680034379.5A CN107849616B (en) 2015-04-13 2016-04-13 Methods and systems for the characterization, diagnosis and treatment of microbiome-derived conditions associated with functional features
AU2022203347A AU2022203347A1 (en) 2015-04-13 2022-05-18 Method and system for microbiome-derived characterization, diaganostics and therapeutics for conditions associated with functional features

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562146818P 2015-04-13 2015-04-13
US62/146,818 2015-04-13
US201562147334P 2015-04-14 2015-04-14
US201562147096P 2015-04-14 2015-04-14
US62/147,334 2015-04-14
US62/147,096 2015-04-14

Publications (2)

Publication Number Publication Date
WO2016168344A1 WO2016168344A1 (en) 2016-10-20
WO2016168344A8 true WO2016168344A8 (en) 2018-07-26

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2016/027349 WO2016168344A1 (en) 2015-04-13 2016-04-13 Method and system for microbiome-derived characterization, diaganostics and therapeutics for conditions associated with functional features

Country Status (4)

Country Link
EP (1) EP3283650A4 (en)
CN (1) CN107849616B (en)
AU (2) AU2016250096A1 (en)
WO (1) WO2016168344A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018094376A1 (en) * 2016-11-21 2018-05-24 uBiome, Inc. Method and system for characterizing a headache-related condition
EP3775257A4 (en) * 2016-12-15 2022-03-09 Psomagen, Inc. Method and system for characterizing allergy-related conditions associated with microorganisms
WO2018112419A1 (en) * 2016-12-15 2018-06-21 uBiome, Inc. Method and system for characterizing diet-related conditions
WO2018112459A1 (en) * 2016-12-16 2018-06-21 uBiome, Inc. Method and system for characterizing microorganism-related conditions
CN112236831A (en) * 2018-06-07 2021-01-15 4D制药有限公司 Method for stratifying IBS patients
EP3946395A4 (en) * 2019-03-29 2023-01-04 Psomagen, Inc. Microbiome byproducts and uses thereof
CN115691813A (en) * 2022-12-30 2023-02-03 神州医疗科技股份有限公司 Genetic gastric cancer assessment method and system based on genomics and microbiomics

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006097949A1 (en) * 2005-03-16 2006-09-21 Actial Farmacêutica, Lda. Mixture of at least 6 species of lactic acid bacteria and/or bifidobacteria in the manufacture of sourdough
US20070134652A1 (en) * 2005-11-09 2007-06-14 Primera Biosystems, Inc. Multiplexed quantitative detection of pathogens
WO2012050513A1 (en) * 2010-10-11 2012-04-19 Baeckhed Fredrik Method for identifying a risk of cardiovascular disease by analysing oral microbiota
KR102027448B1 (en) * 2011-04-28 2019-10-01 슬로안-케테링인스티튜트퍼캔서리서치 Hsp90 combination therapy
US20130121968A1 (en) * 2011-10-03 2013-05-16 Atossa Genetics, Inc. Methods of combining metagenome and the metatranscriptome in multiplex profiles
US20140341853A1 (en) * 2013-05-14 2014-11-20 Vanna Hovanky Bacteria-Mediated Therapy for Cancer
US10633714B2 (en) * 2013-07-21 2020-04-28 Pendulum Therapeutics, Inc. Methods and systems for microbiome characterization, monitoring and treatment

Also Published As

Publication number Publication date
EP3283650A1 (en) 2018-02-21
AU2016250096A8 (en) 2018-12-06
CN107849616A (en) 2018-03-27
WO2016168344A1 (en) 2016-10-20
CN107849616B (en) 2022-03-29
EP3283650A4 (en) 2019-04-10
AU2022203347A1 (en) 2022-06-09
AU2016250096A1 (en) 2017-11-09

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