WO2016162672A3 - Avian vaccine - Google Patents

Avian vaccine Download PDF

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Publication number
WO2016162672A3
WO2016162672A3 PCT/GB2016/050965 GB2016050965W WO2016162672A3 WO 2016162672 A3 WO2016162672 A3 WO 2016162672A3 GB 2016050965 W GB2016050965 W GB 2016050965W WO 2016162672 A3 WO2016162672 A3 WO 2016162672A3
Authority
WO
WIPO (PCT)
Prior art keywords
gallinae
infestation
infection
avian
infestations
Prior art date
Application number
PCT/GB2016/050965
Other languages
French (fr)
Other versions
WO2016162672A2 (en
Inventor
Alasdair Justice NISBET
Kathryn BARTLEY
John Frederick HUNTLEY
Original Assignee
Moredun Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Moredun Research Institute filed Critical Moredun Research Institute
Priority to JP2017553130A priority Critical patent/JP2018512152A/en
Priority to EP16716646.1A priority patent/EP3280724A2/en
Publication of WO2016162672A2 publication Critical patent/WO2016162672A2/en
Publication of WO2016162672A3 publication Critical patent/WO2016162672A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0003—Invertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Insects & Arthropods (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention is based on the finding that specific antigens derived from Dermanyssus gallinae (D. gallinae: poultry red mite) can be used to raise immune responses in avian species, prone or susceptible to, infection or infestation with/by the same. The immune response raised is protective and may prevent or facilitate the clearance or eradication of a D. gallinae infection/infestation, in or from, an avian host. Furthermore, given the significant health problems associated with D. gallinae infections/infestations, the present invention may not only be used to reduce populations of D. gallinae infection/infestation in avian hosts, but it may also be used as a means of indirectly addressing the numerous secondary diseases and/or conditions associated with D. gallinae infections/infestations.
PCT/GB2016/050965 2015-04-09 2016-04-06 Avian vaccine WO2016162672A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2017553130A JP2018512152A (en) 2015-04-09 2016-04-06 Avian vaccine
EP16716646.1A EP3280724A2 (en) 2015-04-09 2016-04-06 Avian vaccine

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1506041.1A GB201506041D0 (en) 2015-04-09 2015-04-09 Avian vaccine
GB1506041.1 2015-04-09

Publications (2)

Publication Number Publication Date
WO2016162672A2 WO2016162672A2 (en) 2016-10-13
WO2016162672A3 true WO2016162672A3 (en) 2016-11-17

Family

ID=53333536

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2016/050965 WO2016162672A2 (en) 2015-04-09 2016-04-06 Avian vaccine

Country Status (4)

Country Link
EP (1) EP3280724A2 (en)
JP (1) JP2018512152A (en)
GB (1) GB201506041D0 (en)
WO (1) WO2016162672A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201112587D0 (en) * 2011-07-22 2011-09-07 Moredun Res Inst Vaccine
CN111333721A (en) * 2020-03-19 2020-06-26 河北科星药业有限公司 Preparation method of yolk antibody for resisting hydropericardium syndrome and application of corresponding antibody
CN112831476B (en) * 2021-03-03 2022-05-06 江苏省农业科学院 Newcastle disease virus VII-NJ strain and application thereof
CN113185607B (en) * 2021-03-22 2022-05-17 华南农业大学 Preparation method of multivalent avian adenovirus egg yolk antibody

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013014408A2 (en) * 2011-07-22 2013-01-31 Moredun Research Institute Vaccine

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013014408A2 (en) * 2011-07-22 2013-01-31 Moredun Research Institute Vaccine

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
A MULENG ET AL: "Tick-Encoded serine proteinase inhibitors (serpins); potential target antigens for tick vaccine development", THE JOURNAL OF VETERINARY MEDICAL SCIENCE / THE JAPANESE SOCIETY OF VETERINARY SCIENCE, 1 October 2001 (2001-10-01), Japan, pages 1063 - 1069, XP055287678, Retrieved from the Internet <URL:https://www.jstage.jst.go.jp/article/jvms/63/10/63_10_1063/_pdf> [retrieved on 20160712], DOI: 10.1292/jvms.63.1063 *
ARKLE S ET AL: "Immunological control of the poultry red mite", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, NEW YORK ACADEMY OF SCIENCES, US, vol. 1149, 13 November 2008 (2008-11-13) - 15 December 2008 (2008-12-15), pages 36 - 40, XP002692546, ISSN: 1749-6632, DOI: 10.1196/ANNALS.1428.057 *
BARTLEY K ET AL: "Histamine Release Factor from Dermanyssus gallinae (De Geer): Characterization and in vitro assessment as a protective antigen", INTERNATIONAL JOURNAL OF PARASITOLOGY, PERGAMON PRESS, GB, vol. 39, no. 4, 7 October 2008 (2008-10-07) - 1 March 2009 (2009-03-01), pages 447 - 456, XP025926526, ISSN: 0020-7519, [retrieved on 20090131], DOI: 10.1016/J.IJPARA.2008.09.006 *
BARTLEY KATHRYN ET AL: "Assessment of cathepsin D and L-like proteinases of poultry red mite, Dermanyssus gallinae (De Geer), as potential vaccine antigens", PARASITOLOGY, ENGLAND, vol. 139, no. 6, 13 November 2011 (2011-11-13) - 1 May 2012 (2012-05-01), pages 755 - 765, XP009167278, DOI: 10.1017/S0031182011002356 *
DATABASE EMBL [online] 22 December 2011 (2011-12-22), "TSA: Metaseiulus occidentalis MITE_454Assem.sd.6959.C1 mRNA sequence.", XP002759774, retrieved from EBI accession no. EM_TSA:JL013481 Database accession no. JL013481 *
DATABASE EMBL [online] 26 September 2015 (2015-09-26), BARTLEY K. ET AL.: "Dermanyssus gallinae serpin-1", XP002759773, retrieved from EBI Database accession no. ALC78838 *
DATABASE REFSEQ [online] NCBI; 14 June 2012 (2012-06-14), "PREDICTED: serpin Z12-like [Metaseiulus occidentalis] (western predatory mite)", XP002759775, Database accession no. XP_003744266.1 *
HARRINGTON D ET AL: "Characterization of the immune response of domestic fowl following immunization with proteins extracted from Dermanyssus gallinae", VETERINARY PARASITOLOGY, ELSEVIER SCIENCE, AMSTERDAM, NL, vol. 160, no. 3-4, 23 March 2009 (2009-03-23), pages 285 - 294, XP025995308, ISSN: 0304-4017, [retrieved on 20081113], DOI: 10.1016/J.VETPAR.2008.11.004 *
HARRY WATMORE WRIGHT: "Identification of vaccine candidates against the Poultry Red Mite, Dermanyssus gallinae", PH.D. THESIS, 5 July 2011 (2011-07-05), XP055287407, Retrieved from the Internet <URL:https://www.era.lib.ed.ac.uk/bitstream/handle/1842/5703/Wright2011.pdf?sequence=2&isAllowed=y> [retrieved on 20160711] *
IMAMURA S ET AL: "A serine protease inhibitor (serpin) from Haemaphysalis longicornis as an anti-tick vaccine", VACCINE, ELSEVIER LTD, GB, vol. 23, no. 10, 26 January 2005 (2005-01-26), pages 1301 - 1311, XP027651804, ISSN: 0264-410X, [retrieved on 20050126] *
KATHRYN BARTLEY ET AL: "Identification and evaluation of vaccine candidate antigens from the poultry red mite (Dermanyssus gallinae)", INTERNATIONAL JOURNAL OF PARASITOLOGY, vol. 45, no. 13, 19 August 2015 (2015-08-19) - 1 November 2015 (2015-11-01), GB, pages 819 - 830, XP055287501, ISSN: 0020-7519, DOI: 10.1016/j.ijpara.2015.07.004 *
SABINE SCHICHT ET AL: "The predicted secretome and transmembranome of the poultry red mite Dermanyssus gallinae", PARASITES & VECTORS, BIOMED CENTRAL LTD, LONDON UK, vol. 6, no. 1, 11 September 2013 (2013-09-11), pages 259, XP021162094, ISSN: 1756-3305, DOI: 10.1186/1756-3305-6-259 *

Also Published As

Publication number Publication date
JP2018512152A (en) 2018-05-17
EP3280724A2 (en) 2018-02-14
WO2016162672A2 (en) 2016-10-13
GB201506041D0 (en) 2015-05-27

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