WO2016156773A8 - Microbial sensing devices - Google Patents

Microbial sensing devices Download PDF

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Publication number
WO2016156773A8
WO2016156773A8 PCT/GB2016/000062 GB2016000062W WO2016156773A8 WO 2016156773 A8 WO2016156773 A8 WO 2016156773A8 GB 2016000062 W GB2016000062 W GB 2016000062W WO 2016156773 A8 WO2016156773 A8 WO 2016156773A8
Authority
WO
WIPO (PCT)
Prior art keywords
microorganisms
wound
devices
selection factor
selection
Prior art date
Application number
PCT/GB2016/000062
Other languages
French (fr)
Other versions
WO2016156773A1 (en
Inventor
Curtis Dobson
Nishal GOVINDJI-BHATT
Original Assignee
Microbiosensor Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microbiosensor Limited filed Critical Microbiosensor Limited
Publication of WO2016156773A1 publication Critical patent/WO2016156773A1/en
Publication of WO2016156773A8 publication Critical patent/WO2016156773A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/00051—Accessories for dressings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/26—Infectious diseases, e.g. generalised sepsis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention concerns devices for detecting and/or identifying microorganisms in the environment of a wound. The devices comprise a surface with at least one reporting means disposed on it which comprises a metabolic indicator and a selection factor. The selection factor selectively permits growth of microorganisms within the pore and as result the metabolic indicator may only activated by preselected microorganisms. In some embodiments the selection factor restricts device activation to predetermined threshold concentrations of microorganism. The devices are particularly useful for helping a clinician to understand the sensitivity of infecting micro-organisms in a wound to selection factors (which may be antibiotics) that are included in the reporting means. This understanding helps when deciding upon a therapeutic strategy for treating or preventing wound infections.
PCT/GB2016/000062 2015-03-30 2016-03-29 Microbial sensing devices WO2016156773A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1505387.9 2015-03-30
GBGB1505387.9A GB201505387D0 (en) 2015-03-30 2015-03-30 Microbial sensing devices

Publications (2)

Publication Number Publication Date
WO2016156773A1 WO2016156773A1 (en) 2016-10-06
WO2016156773A8 true WO2016156773A8 (en) 2017-02-16

Family

ID=53178316

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2016/000062 WO2016156773A1 (en) 2015-03-30 2016-03-29 Microbial sensing devices

Country Status (2)

Country Link
GB (1) GB201505387D0 (en)
WO (1) WO2016156773A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201616689D0 (en) * 2016-09-30 2016-11-16 Microbiosensor Limited Microbial sensing devices
GB201803437D0 (en) * 2018-03-02 2018-04-18 Secr Defence A disclosure system for detecting surface microorganism contamination

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010085755A1 (en) * 2009-01-26 2010-07-29 Indicator Systems International, Inc. Indicators for detecting the presence of metabolic byproducts from microorganisms
CN102333884B (en) * 2009-02-26 2014-07-23 3M创新有限公司 Methods and articles for detecting deoxyribonuclease activity
WO2012171922A1 (en) * 2011-06-14 2012-12-20 Lantor (Uk) Limited Diagnostic device
GB201120991D0 (en) * 2011-12-07 2012-01-18 Univ Manchester Microsensor

Also Published As

Publication number Publication date
GB201505387D0 (en) 2015-05-13
WO2016156773A1 (en) 2016-10-06

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