WO2016128996A3 - An improved process for preparation of ticagrelor and intermediates thereof - Google Patents

An improved process for preparation of ticagrelor and intermediates thereof Download PDF

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Publication number
WO2016128996A3
WO2016128996A3 PCT/IN2016/050049 IN2016050049W WO2016128996A3 WO 2016128996 A3 WO2016128996 A3 WO 2016128996A3 IN 2016050049 W IN2016050049 W IN 2016050049W WO 2016128996 A3 WO2016128996 A3 WO 2016128996A3
Authority
WO
WIPO (PCT)
Prior art keywords
ticagrelor
preparation
intermediates
improved process
improved
Prior art date
Application number
PCT/IN2016/050049
Other languages
French (fr)
Other versions
WO2016128996A2 (en
Inventor
S. M. M. Mohamed RAHUMAN
arjunan SANKAR
Santha Kumar KUPPUSAMY
A. L. Srinivasan
K. Devendra PRASAD
Original Assignee
Strides Shasun Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Strides Shasun Limited filed Critical Strides Shasun Limited
Publication of WO2016128996A2 publication Critical patent/WO2016128996A2/en
Publication of WO2016128996A3 publication Critical patent/WO2016128996A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ceramic Products (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

An improved, industrially viable, environment friendly and economically significant process for preparation of Ticagrelor is disclosed alongwith novel intermediates for the Ticagrelor synthesis.
PCT/IN2016/050049 2015-02-14 2016-02-09 An improved process for preparation of ticagrelor and intermediates thereof WO2016128996A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN729CH2015 2015-02-14
IN729/CHE/2015 2015-02-14

Publications (2)

Publication Number Publication Date
WO2016128996A2 WO2016128996A2 (en) 2016-08-18
WO2016128996A3 true WO2016128996A3 (en) 2016-10-27

Family

ID=56614271

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2016/050049 WO2016128996A2 (en) 2015-02-14 2016-02-09 An improved process for preparation of ticagrelor and intermediates thereof

Country Status (1)

Country Link
WO (1) WO2016128996A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108892670B (en) * 2018-07-12 2019-12-20 江西国药有限责任公司 Preparation method of high-purity ticagrelor

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014102830A1 (en) * 2012-12-31 2014-07-03 Megafine Pharma (P) Ltd. A process for preparation of ticagrelor and intermediates thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014102830A1 (en) * 2012-12-31 2014-07-03 Megafine Pharma (P) Ltd. A process for preparation of ticagrelor and intermediates thereof

Also Published As

Publication number Publication date
WO2016128996A2 (en) 2016-08-18

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