WO2016081692A2 - Substituted bridged urea analogs as sirtuin modulators - Google Patents

Substituted bridged urea analogs as sirtuin modulators Download PDF

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Publication number
WO2016081692A2
WO2016081692A2 PCT/US2015/061501 US2015061501W WO2016081692A2 WO 2016081692 A2 WO2016081692 A2 WO 2016081692A2 US 2015061501 W US2015061501 W US 2015061501W WO 2016081692 A2 WO2016081692 A2 WO 2016081692A2
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WO
WIPO (PCT)
Prior art keywords
mmol
yl
hz
ml
1h
Prior art date
Application number
PCT/US2015/061501
Other languages
French (fr)
Other versions
WO2016081692A3 (en
Inventor
Charles A. Blum
Richard Dana Caldwell
Rebecca Casaubon
Jeremy S. Disch
Ryan Michael Fox
Karsten KOPPETSCH
William Henry Miller
Pui Yee Ng
Christopher Oalmann
Robert B. Perni
Bruce G. Szczepankiewicz
Brian H. White
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Priority to US14/547,861 priority Critical
Priority to US14/547,861 priority patent/US9834558B2/en
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Priority claimed from EP15861618.5A external-priority patent/EP3221312A4/en
Publication of WO2016081692A2 publication Critical patent/WO2016081692A2/en
Publication of WO2016081692A3 publication Critical patent/WO2016081692A3/en

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