WO2016071405A3 - Pharmaceutical preparation and method of its production and use - Google Patents

Pharmaceutical preparation and method of its production and use Download PDF

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Publication number
WO2016071405A3
WO2016071405A3 PCT/EP2015/075724 EP2015075724W WO2016071405A3 WO 2016071405 A3 WO2016071405 A3 WO 2016071405A3 EP 2015075724 W EP2015075724 W EP 2015075724W WO 2016071405 A3 WO2016071405 A3 WO 2016071405A3
Authority
WO
WIPO (PCT)
Prior art keywords
production
pharmaceutical preparation
particles
cationic surfactant
present
Prior art date
Application number
PCT/EP2015/075724
Other languages
French (fr)
Other versions
WO2016071405A2 (en
Inventor
Igor GERASHCHENKO
Oleksii CHEPLIAKA
Andreas Tausch
Original Assignee
Invenres Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2014/073698 external-priority patent/WO2015067603A1/en
Application filed by Invenres Gmbh filed Critical Invenres Gmbh
Priority to EP15788444.6A priority Critical patent/EP3215129A2/en
Priority to US15/523,872 priority patent/US20170312221A1/en
Priority to CA2966089A priority patent/CA2966089A1/en
Publication of WO2016071405A2 publication Critical patent/WO2016071405A2/en
Publication of WO2016071405A3 publication Critical patent/WO2016071405A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics

Abstract

Thus, the present invention provides a composition in powder form comprising highly dispersed silica particles, polymethylsiloxane particles, and a cationic surfactant, wherein at least 25 % by weight of the cationic surfactant is present in primary polymethylsiloxane particles carrying the cationic surfactant on their surface and/or in agglomerates of these primary particles.
PCT/EP2015/075724 2013-11-06 2015-11-04 Pharmaceutical preparation and method of its production and use WO2016071405A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP15788444.6A EP3215129A2 (en) 2014-11-04 2015-11-04 Pharmaceutical preparation and method of its production and use
US15/523,872 US20170312221A1 (en) 2013-11-06 2015-11-04 Pharmaceutical preparation and method of its production and use
CA2966089A CA2966089A1 (en) 2013-11-06 2015-11-04 Pharmaceutical preparation and method of its production and use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EPPCT/EP2014/073698 2014-11-04
PCT/EP2014/073698 WO2015067603A1 (en) 2013-11-06 2014-11-04 Pharmaceutical preparation and method of its production and use

Publications (2)

Publication Number Publication Date
WO2016071405A2 WO2016071405A2 (en) 2016-05-12
WO2016071405A3 true WO2016071405A3 (en) 2016-06-23

Family

ID=54366239

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2015/075724 WO2016071405A2 (en) 2013-11-06 2015-11-04 Pharmaceutical preparation and method of its production and use

Country Status (2)

Country Link
EP (1) EP3215129A2 (en)
WO (1) WO2016071405A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2020107394A (en) * 2017-07-20 2021-08-20 Томас ЛЕЙББРАНД TYROTHRICIN FOR USE IN THE TREATMENT OR PREVENTION OF BODY ODOR AND PREPARED FOR THIS PREPARATIONS
UA115857C2 (en) * 2017-08-30 2017-12-26 Олександр Михайлович Мартиненко METHOD FOR METHYLCREMIC ACID HYDROGEL PREPARATION WITH SUPREMOLECULAR STRUCTURAL PROPERTIES AND HYDROGEL OBTAINED BY THIS METHOD
US20210106531A1 (en) * 2018-01-29 2021-04-15 Pathelen Health Care Ag Hydrophilic/hydrophobic pharmaceutical composition and method of its production and use

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA32088C2 (en) * 1998-12-23 2004-07-15 Yurii Mykolaiovych Shevchenko Wound healing preparation and method for its manufacture
EP1721662A1 (en) * 2004-02-05 2006-11-15 TAIYO KAGAKU Co., LTD. Adsorptivity imparting agent containing porous silica
WO2010079209A2 (en) * 2009-01-08 2010-07-15 Golub Alexandr A Compositions for treating wounds and skin conditions
US20100291062A1 (en) * 2007-07-12 2010-11-18 Golub Alexandr A Antimicrobial Composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA82774C2 (en) 2006-09-20 2008-05-12 Tolcheiev Yurii Zakharovych Process for the preparation of sorbing agent based on methylsilicic acid hydrocarbon gel

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA32088C2 (en) * 1998-12-23 2004-07-15 Yurii Mykolaiovych Shevchenko Wound healing preparation and method for its manufacture
EP1721662A1 (en) * 2004-02-05 2006-11-15 TAIYO KAGAKU Co., LTD. Adsorptivity imparting agent containing porous silica
US20100291062A1 (en) * 2007-07-12 2010-11-18 Golub Alexandr A Antimicrobial Composition
WO2010079209A2 (en) * 2009-01-08 2010-07-15 Golub Alexandr A Compositions for treating wounds and skin conditions

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHUIKO O O ET AL: "CHAPTER 5: Application Efficiency of Complex Preparations based on nanodisperse silica in medical practice", 1 January 2009, NANOMATERIALS AND SUPRAMOLECULAR STRUCTURES : PHYSICS, CHEMISTRY, AND APPLICATIONS, SPRINGER SCIENCE, PAGE(S) 53 - 62, ISBN: 978-90-481-2308-7, XP009175454 *
DAWSON P L ET AL: "Antimicrobial activity of nisin-adsorbed silica and corn starch powders", FOOD MICROBIOLOGY, ACADEMIC PRESS LTD, LONDON, GB, vol. 22, no. 1, 1 January 2005 (2005-01-01), pages 93 - 99, XP004527901, ISSN: 0740-0020, DOI: 10.1016/J.FM.2004.04.001 *

Also Published As

Publication number Publication date
EP3215129A2 (en) 2017-09-13
WO2016071405A2 (en) 2016-05-12

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