WO2016065688A1 - 一种能激活肌肤活力和抗衰老的精华液 - Google Patents

一种能激活肌肤活力和抗衰老的精华液 Download PDF

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WO2016065688A1
WO2016065688A1 PCT/CN2014/092496 CN2014092496W WO2016065688A1 WO 2016065688 A1 WO2016065688 A1 WO 2016065688A1 CN 2014092496 W CN2014092496 W CN 2014092496W WO 2016065688 A1 WO2016065688 A1 WO 2016065688A1
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skin
essence
aging
activating skin
skin vitality
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PCT/CN2014/092496
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彭海英
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彭海英
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Definitions

  • the invention relates to the field of skin care products, in particular to an essence liquid which can activate skin vitality and anti-aging.
  • Skin aging is a continually progressive physiological process that directly affects the appearance and function of the skin. Wrinkles are a sign of skin aging and are called "the annual ring of life.” With the improvement of people's quality of life, anti-aging to remove wrinkles and return to youth has become a topic of concern for consumers.
  • an essence liquid capable of activating skin vitality and anti-aging which contains SOD 2 to 4 million active units/g, and also includes the following components:
  • the percentage is a percentage by mass.
  • the serum capable of activating skin vitality and anti-aging contains SOD 3 to 4 million active units/g, and further includes the following components:
  • the percentage is a percentage by mass.
  • the mineral water is carbonated water having a pH between 5.5 and 6.5.
  • the mineral water contains calcium ions, sodium ions, magnesium ions, zinc ions, and carbonate ions.
  • the magnesium ion is 0.38 ⁇ 0.07 mg/L
  • the sodium ion is 1.2 ⁇ 0.2 mg/L
  • the zinc ion is 0.42 ⁇ 0.05 mg/L
  • the calcium ion is 4.5 ⁇ 0.5 mg/L
  • the hydrogencarbonate ion is 10.1 ⁇ 1.6 mg / L.
  • a preservative is also included, the preservative being phenoxyethanol, which accounts for 0.1% by mass of the essence formulation.
  • the present invention has the following effects:
  • Moisturizing Collagen contains a hydrophilic natural moisturizing factor, and the triple helix structure can strongly lock the moisture. Moreover, hyaluronic acid has a remarkable moisturizing effect.
  • anti-wrinkle SOD can help protect the skin from UV damage, can effectively scavenge free radicals, block the production of elastase, and inhibit its activity, thereby improving the health of the skin from within.
  • ceramide and tocopherol can effectively improve dry skin, desquamation and roughness; at the same time, ceramide can increase the thickness of epidermal cuticle, improve skin water holding capacity, reduce wrinkles, enhance skin elasticity and delay skin aging.
  • repair snail mucus is a natural animal polysaccharide, which is rich in natural allantoin, collagen protein and vitamins and other active ingredients, can make skin regeneration also has anti-inflammatory and renewal of the skin.
  • human oligopeptide-1 can repair sunscreen and after sunburn, reduce the damage of ultraviolet radiation to the skin, and reduce the growth of dark spots on the skin after sunburn.
  • anti-inflammatory antibacterial the main components of golden chamomile have a good antibacterial and anti-inflammatory effects.
  • synergy carbonated water has a strong penetrating power, can easily reach the depths of the capillaries, promote the body's blood circulation, plus mineral water contains a variety of trace elements, can promote collagen, golden chamomile extract and snail mucus absorb.
  • the present invention unblocks the pores, sterilizes and reduces inflammation, and replenishes the moisture required by the skin, and comprehensively increases Strong cell viability and elasticity, increase skin tightness, remove epidermal metabolites, and help damaged tissue heal and firm skin.
  • the essence of the embodiment 1 can activate skin vitality and anti-aging, including SOD of 2 million active units/g, collagen 3%, ceramide 5%, human oligopeptide-1 of 0.06%, golden chamomile extract 5 %, snail mucus extract 1%, B-glucan 4%, hyaluronic acid 0.5%, tocopherol 8%, vitamin C 2%, phenoxyethanol 0.1%, mineral water added to 100%; The percentage is the mass percentage.
  • the pH of the mineral water is between 5.5 and 6.5, which contains magnesium ions of 0.38 ⁇ 0.07 mg/L, sodium ions of 1.2 ⁇ 0.2 mg/L, zinc ions of 0.42 ⁇ 0.05 mg/L, and calcium ions of 4.5 ⁇ 0.5 mg / L, bicarbonate ion 10.1 ⁇ 1.6 mg / L.
  • the golden chamomile extract is selected from the related products of Xi'an Yuansen Biotechnology Co., Ltd.
  • the snail mucus extract is selected from related products of Weihai Xinwei Trading Co., Ltd.
  • the components may be mixed in the above ratio.
  • Example 2 which activates skin vitality and anti-aging, including SOD of 4 million active units/g, collagen 9%, ceramide 3%, human oligopeptide-1 of 0.1%, golden chamomile extract 2 %, snail mucus extract 3%, B-glucan 1%, hyaluronic acid 2%, tocopherol 4%, vitamin C 1%, phenoxyethanol 0.1%, mineral water added to 100%; The percentage is the mass percentage.
  • the pH of the mineral water is between 5.5 and 6.5, which contains magnesium ions of 0.38 ⁇ 0.07 mg/L, sodium ions of 1.2 ⁇ 0.2 mg/L, zinc ions of 0.42 ⁇ 0.05 mg/L, and calcium ions of 4.5 ⁇ 0.5mg/L, bicarbonate Sub 10.1 ⁇ 1.6 mg / L.
  • the golden chamomile extract is selected from the related products of Xi'an Yuansen Biotechnology Co., Ltd.
  • the snail mucus extract is selected from related products of Weihai Xinwei Trading Co., Ltd.
  • the components may be mixed in the above ratio.
  • the essence of the embodiment 3 can activate skin vitality and anti-aging, including SOD of 3 million active units/g, collagen 6%, ceramide 4%, human oligopeptide-1 of 0.08%, golden chamomile extract 4 %, snail mucus extract 2%, B-glucan 3%, hyaluronic acid 1.5%, tocopherol 6%, vitamin C 1.5%, phenoxyethanol 0.1%, mineral water added to 100%; The percentage is the mass percentage.
  • the pH of the mineral water is between 5.5 and 6.5, which contains magnesium ions of 0.38 ⁇ 0.07 mg/L, sodium ions of 1.2 ⁇ 0.2 mg/L, zinc ions of 0.42 ⁇ 0.05 mg/L, and calcium ions of 4.5 ⁇ 0.5 mg / L, bicarbonate ion 10.1 ⁇ 1.6 mg / L.
  • the golden chamomile extract is selected from the related products of Xi'an Yuansen Biotechnology Co., Ltd.
  • the snail mucus extract is selected from related products of Weihai Xinwei Trading Co., Ltd.
  • the components may be mixed in the above ratio.
  • the present invention performs the following tests:
  • Case-related data 80 patients with loose skin, more wrinkles, and more pigmented epidermis were selected, aged between 30-55 years old.
  • Invalid the user feels dissatisfied, the skin is rough and dry, no significant improvement, wrinkles are not reduced, skin elasticity and lubricity are not increased; the skin texture density under the microscope is not significantly improved, and the pigmentation of the epidermis is not significantly improved.
  • the total effective rate of the present invention is 96.25%, and the same effects are obtained in Examples 2 to 3.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
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  • Cosmetics (AREA)

Abstract

一种能激活肌肤活力和抗衰老的精华液，包括SOD为200～400万个活性单位/g，胶原蛋白3～9%，神经酰胺3～5%，人寡肽-1为0.06～0.1%，金黄洋甘菊提取物2～5%，蜗牛粘液提取物1～3%，β-葡聚糖1～4%，透明质酸0.5～2%，生育酚4～8%，维生素C为1～2%，矿物质水余量；所述百分比为质量百分比。

Description

一种能激活肌肤活力和抗衰老的精华液 技术领域
本发明涉及护肤品领域，具体涉及一种能激活肌肤活力和抗衰老的精华液。
背景技术
皮肤老化是一种持续渐进性的生理过程，直接影响皮肤的外观与功能。皱纹则是皮肤老化表现的一种标志，被称之为“人生的年轮”。随着人们生活质量的提高，防衰老去除皱纹、重返青春成了广大消费者关注的话题。
随着生化科技的发展，人们正逐渐揭开皱纹的生理机制，使用生理活性物质改善皮肤因松弛而出现皱纹的可能性越来越大，以化妆品厂家为中心，近年来让脸上青春永驻的尖端研究各位引人注目。因而，防衰老抗皱化妆品越来越被人们重视，随着人们的生活水平日益提高，对美容、护肤产品的质量要求也越来越高。虽然某些护肤品对人的皮肤有短期的美白、护肤作用，但如果长期使用，反而会使皮肤形成色斑，严重地，甚至有可能导致人体器官发生病变。
如今功效保证、无副作用的抗衰老护肤品一直都是研究的课题，但是很多护肤品的功效都不尽如人意。
发明内容
本发明解决该技术问题所采用的技术方案是：一种能激活肌肤活力和抗衰老的精华液，其含有SOD 200～400万个活性单位/g，还包括以下组分：
Figure PCTCN2014092496-appb-000001
Figure PCTCN2014092496-appb-000002
所述百分比为质量百分比。
作为优选的技术方案，所述能激活肌肤活力和抗衰老的精华液，其含有SOD300～400万个活性单位/g，还包括以下组分：
Figure PCTCN2014092496-appb-000003
所述百分比为质量百分比。
进一步，所述矿物质水为pH值在5.5～6.5之间的碳酸水。所述矿物质水含有钙离子、钠离子、镁离子、锌离子及碳酸根离子。其中，所述镁离子为 0.38±0.07mg/L，所述钠离子为1.2±0.2mg/L，所述锌离子为0.42±0.05mg/L，所述钙离子为4.5±0.5mg/L，所述碳酸氢根离子为10.1±1.6mg/L。
进一步，还包括防腐剂，所述防腐剂为苯氧乙醇，其占该精华液配方的质量百分比为0.1％。
与现有技术相比，本发明具有如下效果：
1、保湿：胶原蛋白含亲水性的天然保湿因子，三螺旋结构能强劲锁住水分。而且，透明质酸具有显著的保湿功效。
2、紧肤：当胶原蛋白被皮肤吸收后，填充在皮肤真皮之间，增加皮肤紧密度，产生皮肤张力，缩小毛孔，使皮肤紧绷而富有弹性。
3、抗皱：SOD可协助保护皮肤免受紫外线的损伤，能够有效地清除自由基，阻断弹性蛋白酶的产生，并抑制其活性，从而从内部改善皮肤的健康状况。而且，神经酰胺及生育酚有效改善皮肤干燥、脱屑、粗糙；同时神经酰胺能增加表皮角质层厚度，提高皮肤持水能力，减少皱纹，增强皮肤弹性，延缓皮肤衰老。
4、修复：蜗牛黏液是一种天然性的动物性多糖体，其含有丰富的天然尿囊素、骨胶原蛋白质和维生素等有效成份，可以使皮肤再生还具有消炎和更新肌肤的作用。而且，人寡肽-1能防晒及晒后修复，减轻紫外线辐射对皮肤的伤害，减少晒后皮肤的黑斑生长。
5、消炎抗菌：金黄洋甘菊的主要成分有很好的抗菌消炎作用。
6、协同作用：碳酸水具有很强的渗透力，能够轻松直达毛细血管深处，促进机体血液循环，加之矿物质水中含有多种微量元素，能促进胶原蛋白、金黄洋甘菊提取物及蜗牛黏液的吸收。
由此可见，本发明疏通受阻毛孔，杀菌消炎，补充肌肤所需水分，全面增 强细胞活力及弹性，增加皮肤紧密度，清除表皮暗淡代谢物，还可帮助受损的组织愈合及紧实肌肤。
下面结合实施例对本发明作进一步说明。
具体实施方式
实施例1
实施例1的能激活肌肤活力和抗衰老的精华液，包括SOD为200万个活性单位/g，胶原蛋白3％，神经酰胺5％，人寡肽-1为0.06％，金黄洋甘菊提取物5％，蜗牛粘液提取物1％，B-葡聚糖4％，透明质酸0.5％，生育酚8％，维生素C为2％，苯氧乙醇0.1％，矿物质水加至100％；所述百分比为质量百分比。
其中，所述矿物质水的pH值在5.5～6.5之间，其含有镁离子0.38±0.07mg/L，钠离子1.2±0.2mg/L，锌离子0.42±0.05mg/L，钙离子4.5±0.5mg/L，碳酸氢根离子10.1±1.6mg/L。
其中，所述金黄洋甘菊提取物选自西安源森生物科技有限公司的相关产品，所述蜗牛粘液提取物选自威海鑫威贸易有限公司的相关产品。
将所述组分按上述配比混合即可。
实施例2
实施例2的能激活肌肤活力和抗衰老的精华液，包括SOD为400万个活性单位/g，胶原蛋白9％，神经酰胺3％，人寡肽-1为0.1％，金黄洋甘菊提取物2％，蜗牛粘液提取物3％，B-葡聚糖1％，透明质酸2％，生育酚4％，维生素C为1％，苯氧乙醇0.1％，矿物质水加至100％；所述百分比为质量百分比。
其中，所述矿物质水的pH值在5.5～6.5之间，其含有镁离子0.38±0.07mg/L，钠离子1.2±0.2mg/L，锌离子0.42±0.05mg/L，钙离子4.5±0.5mg/L，碳酸氢根离 子10.1±1.6mg/L。
其中，所述金黄洋甘菊提取物选自西安源森生物科技有限公司的相关产品，所述蜗牛粘液提取物选自威海鑫威贸易有限公司的相关产品。
将所述组分按上述配比混合即可。
实施例3
实施例3的能激活肌肤活力和抗衰老的精华液，包括SOD为300万个活性单位/g，胶原蛋白6％，神经酰胺4％，人寡肽-1为0.08％，金黄洋甘菊提取物4％，蜗牛粘液提取物2％，B-葡聚糖3％，透明质酸1.5％，生育酚6％，维生素C为1.5％，苯氧乙醇0.1％，矿物质水加至100％；所述百分比为质量百分比。
其中，所述矿物质水的pH值在5.5～6.5之间，其含有镁离子0.38±0.07mg/L，钠离子1.2±0.2mg/L，锌离子0.42±0.05mg/L，钙离子4.5±0.5mg/L，碳酸氢根离子10.1±1.6mg/L。
其中，所述金黄洋甘菊提取物选自西安源森生物科技有限公司的相关产品，所述蜗牛粘液提取物选自威海鑫威贸易有限公司的相关产品。
将所述组分按上述配比混合即可。
本发明进行如下试验：
病例相关资料：选取80例肌肤松弛粗糙、皱纹多、表皮色素沉着多的试验者，年龄介于30-55岁之间。
使用方法：彻底洁肤后，将实施例1制备得到的精华液均匀地涂抹肌肤上，轻轻拍打，早晚各使用一次，每28天为一个疗程，使用1～4个疗程。
评判标准：
显效：使用者自我感觉非常满意，肌肤具有弹性更紧实幼滑，皮肤细腻润 泽，肌肤持久水润柔滑光泽，皱纹明显减少；显微镜下皮肤纹理密度明显减少，皮肤颜色明显变浅。受试者均无过敏或其他毒副反应。
有效：使用者自我感觉一般满意，皮肤弹性光泽润滑度有所增加；皱纹有所减少；显微镜下皮肤纹理密度有所减少，皮肤颜色变浅。
无效：使用者自我感觉不满意，肌肤粗糙干燥感无明显改善，皱纹无减少，皮肤弹性光泽润滑度无增加；显微镜下皮肤纹理密度无明显改善，表皮色素沉着无明显改善。
使用效果
对这80例进行记录和回访，具体结果如表1：
Figure PCTCN2014092496-appb-000004
表1
在使用期间，受试者均无过敏或其他毒副反应发生。本发明总有效率达到96.25％，实施例2～3也有同样的效果。
本发明并不局限于上述实施方式，如果对本发明的各种改动或变型不脱离本发明的精神和范围，倘若这些改动和变型属于本发明的权利要求和等同技术范围之内，则本发明也意图包含这些改动和变型。

Claims (7)

  1. 一种能激活肌肤活力和抗衰老的精华液，其特征在于，其含有SOD 200～400万个活性单位/g，还包括以下组分：
    Figure PCTCN2014092496-appb-100001
    所述百分比为质量百分比。
  2. 如权利要求1所述能激活肌肤活力和抗衰老的精华液，其特征在于：其含有SOD 300～400万个活性单位/g，还包括以下组分：
    Figure PCTCN2014092496-appb-100002
    Figure PCTCN2014092496-appb-100003
    所述百分比为质量百分比。
  3. 如权利要求1或2所述能激活肌肤活力和抗衰老的精华液，其特征在于：所述矿物质水为pH值在5.5～6.5之间的碳酸水。
  4. 如权利要求3所述能激活肌肤活力和抗衰老的精华液，其特征在于：所述矿物质水含有钙离子、钠离子、镁离子、锌离子及碳酸根离子。
  5. 如权利要求4所述能激活肌肤活力和抗衰老的精华液，其特征在于：所述镁离子为0.38±0.07mg/L，所述钠离子为1.2±0.2mg/L，所述锌离子为0.42±0.05mg/L，所述钙离子为4.5±0.5mg/L，所述碳酸氢根离子为10.1±1.6mg/L。
  6. 如权利要求1或2所述能激活肌肤活力和抗衰老的精华液，其特征在于：还包括防腐剂。
  7. 如权利要求6所述能激活肌肤活力和抗衰老的精华液，其特征在于：所述防腐剂为苯氧乙醇，其占该精华液配方的质量百分比为0.1％。
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