WO2016060576A1 - Liquide contenant de la cytisine pour cigarettes électroniques - Google Patents
Liquide contenant de la cytisine pour cigarettes électroniques Download PDFInfo
- Publication number
- WO2016060576A1 WO2016060576A1 PCT/PL2015/000168 PL2015000168W WO2016060576A1 WO 2016060576 A1 WO2016060576 A1 WO 2016060576A1 PL 2015000168 W PL2015000168 W PL 2015000168W WO 2016060576 A1 WO2016060576 A1 WO 2016060576A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cytisine
- liquid
- electronic cigarettes
- nicotine
- cigarettes
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
-
- A—HUMAN NECESSITIES
- A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
- A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
- A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
- A24B15/10—Chemical features of tobacco products or tobacco substitutes
- A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
- A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
Definitions
- the subject of the invention is a liquid with an addition of organic chemical compound with formula Cj 1H14 2O named popularly cytisine to be used in electronic cigarettes and related tobacco industry products for the purposes of substitution therapy in treatment of the nicotine addiction syndrome.
- E-cigarettes In the current state of the art, the tobacco industry manufactures many types of liquids to be used to refill electronic cigarettes for the purpose of inhaling vapours containing nicotine.
- E-cigarettes neither contain any combustible plant material nor generate any cigarette smoke; however, they contain nicotine as well as aromatic substances and produce nicotine-containing vapours.
- Cytisine demonstrates effects similar to those produced by nicotine, has a stimulating effect on autonomic nervous system, mainly the respiratory centre. It stimulates also the vasomotor centre, increases secretion of adrenaline and results in an increase of blood pressure.
- cytisine is administered in small doses in the form of tablets, as a substitute for nicotine in mitigation of nicotine cravings in the course of therapies aimed at reduction of negative effects of nicotinism. It has been proven that cytisine shows less addictive properties than nicotine and is useful in mitigation of nicotine craving symptoms.
- the objective of the invention entitled "A liquid with cytisine for electronic cigarettes” is to provide a liquid for e-cigarettes containing an addition of extracted or synthetically obtained cytisine in a dose ranging from 0.000000001% to 99.999999999% of given liquid volume.
- This problem has been solved by combining a liquid, solution, and/or emulsion or a mixture thereof in the amount of from 0.000000001% to 99.999999999% of given quantity of the liquefied mass with a dose of cytisine ranging from 0.000000001%) to 99.999999999% in such a way that the added cytisine increases the mass of said liquid and changes its properties, as a result of which a liquid is obtained characterised in that it contains substances other than nicotine in the amount from 0.000000001% to 99.999999999% of the liquid volume and a dose of cytisine in the amount from 0.000000001% to 99.999999999%.
- cytisine is placed in the volume of the liquid.
- a distinctive feature of the solution with respect to known solutions of the so-called e-liquids consists in combination of a given dose of cytisine and a liquid into a single product with properties of a liquid is such a way that, contrary to traditional liquids, it contains a measured dose of cytisine.
- Intermediate products in the manufacturing process are: a liquid material prepared according to any formula applied by tobacco industry manufacturers and cytisine of natural origin and/or obtained synthetically, as a result of genetic modification, or a combination of these processes.
- Cytisine is placed in glycol solution in the proportion of 90% glycol and 10% cytisine by weight as granulate, powder, emulsion, suspension, solution, deposit, material, conglomerate and/or a mixture with arbitrary proportions of these intermediate products obtained by means of chemical reactions, physical processes, genetic modifications or any combination thereof, and then subject to further processing.
- the liquids manufactured according to the invented method when applied in vapour generators known commonly as electronic cigarettes and inhaled the form of vapours, allow to release cytisine of organic origin or obtained synthetically. Cytisine contained in the smoke of such cigarette in doses according to the invention and released from electronic cigarette gets inside, through lungs of the electronic cigarette user, to blood and produces its effect on organism of the smoking person.
Abstract
L'invention concerne un liquide pour cigarettes électroniques caractérisé en ce que, dans un volume de la masse liquéfiée, il contient une dose de cystisine dans une proportion comprise entre 0,000000001 % et 99,999999999 % du volume de liquide total.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PL409829A PL409829A1 (pl) | 2014-10-18 | 2014-10-18 | Płyn z cytyzyną do elektronicznych papierosów |
PLP.409829 | 2014-10-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2016060576A1 true WO2016060576A1 (fr) | 2016-04-21 |
Family
ID=54705776
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/PL2015/000168 WO2016060576A1 (fr) | 2014-10-18 | 2015-10-16 | Liquide contenant de la cytisine pour cigarettes électroniques |
Country Status (2)
Country | Link |
---|---|
PL (1) | PL409829A1 (fr) |
WO (1) | WO2016060576A1 (fr) |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USD825102S1 (en) | 2016-07-28 | 2018-08-07 | Juul Labs, Inc. | Vaporizer device with cartridge |
US10045567B2 (en) | 2013-12-23 | 2018-08-14 | Juul Labs, Inc. | Vaporization device systems and methods |
US10045568B2 (en) | 2013-12-23 | 2018-08-14 | Juul Labs, Inc. | Vaporization device systems and methods |
US10058130B2 (en) | 2013-12-23 | 2018-08-28 | Juul Labs, Inc. | Cartridge for use with a vaporizer device |
US10076139B2 (en) | 2013-12-23 | 2018-09-18 | Juul Labs, Inc. | Vaporizer apparatus |
US10104915B2 (en) | 2013-12-23 | 2018-10-23 | Juul Labs, Inc. | Securely attaching cartridges for vaporizer devices |
US10111470B2 (en) | 2013-12-23 | 2018-10-30 | Juul Labs, Inc. | Vaporizer apparatus |
USD836541S1 (en) | 2016-06-23 | 2018-12-25 | Pax Labs, Inc. | Charging device |
USD842536S1 (en) | 2016-07-28 | 2019-03-05 | Juul Labs, Inc. | Vaporizer cartridge |
US10244793B2 (en) | 2005-07-19 | 2019-04-02 | Juul Labs, Inc. | Devices for vaporization of a substance |
US10279934B2 (en) | 2013-03-15 | 2019-05-07 | Juul Labs, Inc. | Fillable vaporizer cartridge and method of filling |
USD849996S1 (en) | 2016-06-16 | 2019-05-28 | Pax Labs, Inc. | Vaporizer cartridge |
USD851830S1 (en) | 2016-06-23 | 2019-06-18 | Pax Labs, Inc. | Combined vaporizer tamp and pick tool |
US10405582B2 (en) | 2016-03-10 | 2019-09-10 | Pax Labs, Inc. | Vaporization device with lip sensing |
US10512282B2 (en) | 2014-12-05 | 2019-12-24 | Juul Labs, Inc. | Calibrated dose control |
USD887632S1 (en) | 2017-09-14 | 2020-06-16 | Pax Labs, Inc. | Vaporizer cartridge |
US10865001B2 (en) | 2016-02-11 | 2020-12-15 | Juul Labs, Inc. | Fillable vaporizer cartridge and method of filling |
EP3967298A1 (fr) | 2020-06-30 | 2022-03-16 | Uniwersytet Rzeszowski | Composition en aérosol à usage oral |
CN114727647A (zh) * | 2019-09-12 | 2022-07-08 | 阿奇维生命科学公司 | 治疗和/或预防有需要的受试者的成瘾的包括野靛碱的组合物 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2011136100A (ru) * | 2011-08-31 | 2013-03-10 | Александр Васильевич Иващенко | Фармацевтическая композиция, способ ее получения и устройство для ее применения |
EP2815741A1 (fr) * | 2013-06-20 | 2014-12-24 | Changning Dekang Biotechnology Co., Ltd | Liquide atomisé de cytisine à nicotine orale substituée et son procédé de préparation |
-
2014
- 2014-10-18 PL PL409829A patent/PL409829A1/pl unknown
-
2015
- 2015-10-16 WO PCT/PL2015/000168 patent/WO2016060576A1/fr active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2011136100A (ru) * | 2011-08-31 | 2013-03-10 | Александр Васильевич Иващенко | Фармацевтическая композиция, способ ее получения и устройство для ее применения |
EP2815741A1 (fr) * | 2013-06-20 | 2014-12-24 | Changning Dekang Biotechnology Co., Ltd | Liquide atomisé de cytisine à nicotine orale substituée et son procédé de préparation |
Cited By (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10244793B2 (en) | 2005-07-19 | 2019-04-02 | Juul Labs, Inc. | Devices for vaporization of a substance |
US10638792B2 (en) | 2013-03-15 | 2020-05-05 | Juul Labs, Inc. | Securely attaching cartridges for vaporizer devices |
US10279934B2 (en) | 2013-03-15 | 2019-05-07 | Juul Labs, Inc. | Fillable vaporizer cartridge and method of filling |
US10104915B2 (en) | 2013-12-23 | 2018-10-23 | Juul Labs, Inc. | Securely attaching cartridges for vaporizer devices |
US11752283B2 (en) | 2013-12-23 | 2023-09-12 | Juul Labs, Inc. | Vaporization device systems and methods |
US10264823B2 (en) | 2013-12-23 | 2019-04-23 | Juul Labs, Inc. | Vaporization device systems and methods |
US10070669B2 (en) | 2013-12-23 | 2018-09-11 | Juul Labs, Inc. | Cartridge for use with a vaporizer device |
US10076139B2 (en) | 2013-12-23 | 2018-09-18 | Juul Labs, Inc. | Vaporizer apparatus |
US10045568B2 (en) | 2013-12-23 | 2018-08-14 | Juul Labs, Inc. | Vaporization device systems and methods |
US10111470B2 (en) | 2013-12-23 | 2018-10-30 | Juul Labs, Inc. | Vaporizer apparatus |
US10117465B2 (en) | 2013-12-23 | 2018-11-06 | Juul Labs, Inc. | Vaporization device systems and methods |
US10117466B2 (en) | 2013-12-23 | 2018-11-06 | Juul Labs, Inc. | Vaporization device systems and methods |
US10159282B2 (en) | 2013-12-23 | 2018-12-25 | Juul Labs, Inc. | Cartridge for use with a vaporizer device |
US10912331B2 (en) | 2013-12-23 | 2021-02-09 | Juul Labs, Inc. | Vaporization device systems and methods |
US10201190B2 (en) | 2013-12-23 | 2019-02-12 | Juul Labs, Inc. | Cartridge for use with a vaporizer device |
US10701975B2 (en) | 2013-12-23 | 2020-07-07 | Juul Labs, Inc. | Vaporization device systems and methods |
US10058130B2 (en) | 2013-12-23 | 2018-08-28 | Juul Labs, Inc. | Cartridge for use with a vaporizer device |
US10058124B2 (en) | 2013-12-23 | 2018-08-28 | Juul Labs, Inc. | Vaporization device systems and methods |
US10667560B2 (en) | 2013-12-23 | 2020-06-02 | Juul Labs, Inc. | Vaporizer apparatus |
US10058129B2 (en) | 2013-12-23 | 2018-08-28 | Juul Labs, Inc. | Vaporization device systems and methods |
US10045567B2 (en) | 2013-12-23 | 2018-08-14 | Juul Labs, Inc. | Vaporization device systems and methods |
US10512282B2 (en) | 2014-12-05 | 2019-12-24 | Juul Labs, Inc. | Calibrated dose control |
US10865001B2 (en) | 2016-02-11 | 2020-12-15 | Juul Labs, Inc. | Fillable vaporizer cartridge and method of filling |
US10405582B2 (en) | 2016-03-10 | 2019-09-10 | Pax Labs, Inc. | Vaporization device with lip sensing |
USD929036S1 (en) | 2016-06-16 | 2021-08-24 | Pax Labs, Inc. | Vaporizer cartridge and device assembly |
USD849996S1 (en) | 2016-06-16 | 2019-05-28 | Pax Labs, Inc. | Vaporizer cartridge |
USD913583S1 (en) | 2016-06-16 | 2021-03-16 | Pax Labs, Inc. | Vaporizer device |
USD836541S1 (en) | 2016-06-23 | 2018-12-25 | Pax Labs, Inc. | Charging device |
USD851830S1 (en) | 2016-06-23 | 2019-06-18 | Pax Labs, Inc. | Combined vaporizer tamp and pick tool |
USD842536S1 (en) | 2016-07-28 | 2019-03-05 | Juul Labs, Inc. | Vaporizer cartridge |
USD825102S1 (en) | 2016-07-28 | 2018-08-07 | Juul Labs, Inc. | Vaporizer device with cartridge |
USD887632S1 (en) | 2017-09-14 | 2020-06-16 | Pax Labs, Inc. | Vaporizer cartridge |
CN114727647A (zh) * | 2019-09-12 | 2022-07-08 | 阿奇维生命科学公司 | 治疗和/或预防有需要的受试者的成瘾的包括野靛碱的组合物 |
EP3967298A1 (fr) | 2020-06-30 | 2022-03-16 | Uniwersytet Rzeszowski | Composition en aérosol à usage oral |
Also Published As
Publication number | Publication date |
---|---|
PL409829A1 (pl) | 2016-04-25 |
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