WO2016022021A1 - Sequence linked to fruit coat trait - Google Patents

Abstract

A method of predicting or determining fruit exocarp trait of an oil palm fruit, the method comprising detecting the presence or absence of one or more genetic markers located in Haplotype Block A, wherein Haplotype Block A comprises or consists of SEQ ID NO: 13295 or SEQ ID NOs: 13020 to 13294.

Description

SEQUENCE LINKED TO FRUIT COAT TRAIT

TECHNICAL FIELD The present invention relates generally to the field of plant molecular biology. In particular, the present invention relates to detection and use of plant genetic markers for selection of desired traits in oil palms.

BACKGROUND

In oil palm fruit bunches, the fruit changes colour during the ripening process and the colour of the fruit, and by extension the colour of the oil palm fruit bunch, is used as a visual indicator to determine ripeness before harvesting. There are two main types of common external appearances, the "nigrescens" and the "virescens" fruit type, which are also known as fruit exocarp colour types. The exocarp of the nigrescens fruit type is deep violet to blackish at the fruit apex, and is pale greenish-yellow (or sometimes also described as "colourless") at the base of the fruit when it is unripe. During ripening, the exocarp changes colour to entirely red or black over the upper half, but is red at the base of the fruit. In contrast, the virescens fruit type is green when unripe, and changes to a shade of orange-red when ripe.

For practical use in oil palm plantations, the fruit colour is useful as an indicator of ripeness, assisting in deciding if an oil palm is ripe enough for harvest. Often, oil palm bunches could be high up in the tree so that close inspection of the fruit bunch is not practical. Therefore, the fruit colours, as well as several other factors, are used to make the decision whether or not to harvest the fruit. Due to the dramatic change of colour from green to orange-red, it is easier to determine if virescens bunches are ready to be harvested, compared to nigrescens bunches. The visual harvesting index is important to avoid harvesting under-ripe bunches, which would result in an overall lower total oil content being obtained from the processing of these bunches. Conversely, waiting too long and harvesting over-ripe bunches will not only lead to higher fruit abscission from the oil palm bunches, but will also lead to high free fatty acid levels in the oils obtained from such bunches. Besides being indicators of ripeness, the variation in fruit colour also reflects the carotenoid content, with the nigrescens fruit type containing more carotenoid than the virescens fruit type. Based on previous observation and research, a single gene or a single locus is known to control fruit exocarp type colour, which also determines if an oil palm will produce virescens or nigrescens fruits. Light is known as a factor that can regulate expression of genes encoding proteins involved in the anthocyanin biosynthesis pathway through the induction of transcription factors (TF). This mechanism, which alters and controls colour pigmentation, has been observed in various plant species such as petunia, snapdragon, tomato, orchid, cacao and apple. It was hypothesized that the expression of genes encoding enzymes involved in the anthocyanin biosynthesis pathway can be coordinatively regulated by multiple transcription factors. This has been used as the basis for studying the early and ripe stages of fruit development for the virescens and nigrescens oil palm exocarp through gene expression profile analysis.

In spite of what is known in the prior art, information on the genetic region surrounding the locus controlling the virescens-nigrescens trait is still lacking and insufficient to allow for the design of markers for fruit exocarp colour types that can be used to predict or identify fruit exocarp colour types in multiple oil palm populations with near perfect accuracy. Hence, there is a need for gene- or protein-based methods that can accurately predict or identify fruit exocarp colour types in oil palms, and that can be applied across multiple oil palm populations.

SUMMARY

In a first aspect, there is provided a method of predicting or determining fruit exocarp trait of an oil palm fruit, the method comprising detecting the presence or absence of one or more genetic markers located in Haplotype Block A, wherein Haplotype Block A comprises or consists of SEQ ID NO: 13295 or alternatively SEQ ID NOs: 13020 to 13294.

In a second aspect, there is provided a method for selecting an oil palm plant for breeding, comprising using one or more genetic marker as defined herein, wherein the selection is based on the presence or absence of the genetic marker within a Haplotype Block as defined herein.

DEFINITIONS

The following words and terms used herein shall have the meaning indicated:

The term "haplotype", as used herein, refers to a cluster of genetic markers that are typically inherited together. The haplotype may be a combination of alleles or a set of markers such as, but not limited to, single nucleotide polymorphisms (SNPs), which are variations at single positions in the DNA sequence in a part of a chromosome (i.e. a chromosomal interval) among individuals. The combination of alleles or set of markers (such as SNPs) may be found on the same chromosome.

The term "haplotype block", as used herein, refers to a region of a chromosome, exhibiting high linkage disequilibrium (LD), within which one or more haplotypes are located. In addition to the haplotype, a haplotype block may include additional genetic elements, such as, but not limited to, polymorphic sites, gene sequences, transcription factors, primer initiation sites or transcription start sites. As used herein, the term "variant" refers to a form or version of something that differs in some respect from other forms of the same thing or from a standard.

The term "polymorphism", as used herein, refers to a variation or difference in the sequence of a genetic region that arises in some of the members of a species. Variant sequences can be defined with reference to an arbitrary or non-arbitrary standard sequence for the species. A polymorphism is thus said to be "allelic," in that, due to the existence of the polymorphism, some members of a species may have the "standard" sequence (i.e. the standard "allele") whereas other members may have a variant sequence (i.e., a variant "allele"). Thus, as used herein, an allele is one of two or more alternative versions of a gene or other genetic region at a particular location on a chromosome. In the simplest case, only one variant sequence may exist, and the polymorphism is thus said to be bi-allelic. In other cases, the species' population may contain multiple alleles, and the polymorphism is termed tri-allelic, etc. A single gene or genetic region may have multiple different unrelated polymorphisms. For example, it may have one bi-allelic polymorphism at one site, another bi-allelic polymorphism at another site and a multi-allelic polymorphism at yet another site. When all the sequences for a group of alleles at a chromosomal locus in a plant are the same, the alleles are said to be "homozygous" at that locus. When the sequence of any allele at a particular locus in a plant is different, the population of alleles is said to be "heterozygous" at that locus. Polymorphisms at a particular chromosomal locus can affect the phenotypic trait associated with that locus.

The term "variant" can also include a reference to substantially similar sequences. Generally, nucleic acid sequence variants of the invention encode a polypeptide which retains qualitative biological activity in common with the polypeptide encoded by the "non-variant" nucleic acid sequence. Generally, polypeptide sequence variants of the invention also possess qualitative biological activity in common with the "non-variant" polypeptide. Further, these polypeptide sequence variants may have at least 25%, 30%, 35%, 40%, 45%, 50%, 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, 96%, 97%,

98% or 99% sequence identity to the "non-variant" polypeptide. Variants may be made using, for example, the methods of protein engineering and site-directed mutagenesis as is well known in the art. Further, a variant polypeptide may include analogues, wherein the term "analogue" as used herein with reference to a polypeptide means a polypeptide which is a derivative of the polypeptide of the invention, which derivative comprises addition, deletion, substitution of one or more amino acids, such that the polypeptide retains substantially the same function as the "non-variant" polypeptide. The substitution may be one or more conservative amino acid substitutions. The term "conservative amino acid substitution" as used herein refers to a substitution or replacement of one amino acid for another amino acid with similar properties within a polypeptide chain (primary sequence of a protein). For example, the substitution of the charged amino acid glutamic acid (Glu) for the similarly charged amino acid aspartic acid (Asp) would be a conservative amino acid substitution.

Detection of the polypeptides or variants thereof of the present invention may be achieved using a variety of techniques including ELISA (enzyme linked immunosorbent assay), Western blotting, immunoprecipitation and immunofluorescence. Such techniques are commonly used by those of skill in the art.

As used herein, "sequence identity" refers to the residues in two sequences that are the same when aligned for maximum correspondence over a specified window of comparison by means of computer programs known in the art, such as GAP provided in the GCG program package (Program Manual for the Wisconsin Package, Version 8, August 1996, Genetics Computer Group, 575 Science Drive, Madison, Wisconsin, USA 53711) (Needleman, S.B. and Wunsch, CD., (1970), Journal of Molecular Biology, 48, 443-453).

The term "trait" refers to any particular characteristic exhibited by a plant, whether naturally occurring or otherwise. The trait may be capable of being inherited, i.e. a "phenotypic trait," either transiently or permanently, or may only be present when the plant or part thereof is subjected to environmental stimuli or challenge. In the present disclosure, the trait of interest is the fruit exocarp trait (e.g. colour) in oil palm plants. In some examples disclosed herein, the trait of interest may be referred to as fruit exocarp colour. As used herein, a "marker" or "genetic marker" is an indicator for the presence of at least one mutation or polymorphism. A "polymorphic marker" is therefore a marker capable of detecting one or more polymorphisms. A marker is preferably a nucleic acid. A "nucleic acid marker" therefore means a nucleic acid molecule that is capable of being a marker for detecting a polymorphism. It is understood that a marker can, for example, be an oligonucleotide probe or primer. Molecular markers are preferred for genotyping, because these markers are unlikely to affect the trait of interest. In some examples, the marker may comprise but is not limited to single nucleotide polymorphisms (SNPs), simple sequence repeats (SSRs or microsatellites), insertion or deletion of bases (INDELs), unique-event polymorphism (UEP), amplified fragment length polymorphisms (AFLPs), random amplification of polymorphic DNAs (RAPDs), restriction fragment length polymorphisms (RFLPs), and transposable element positions and combinations thereof.

The term "single nucleotide polymorphism", as defined herein, is a DNA sequence variation that occurs when a single nucleotide (A, T, C, or G) in the genome sequence is altered or differs between members of a biological species. Thus, as used herein, a SNP is any polymorphism characterized by a different single nucleotide at a particular physical position in at least one allele. Each individual in a given population has many single nucleotide polymorphisms that together create a unique DNA pattern for that individual.

As used herein, "simple sequence repeats (SSRs)" also known as microsatellites, or short tandem repeats (STRs), refers to repeating sequences, typically of 2-6 base pairs of DNA. In some examples described herein, the SSRs are repeating sequences of 2 base pairs, 3 base pairs, or 4 base pairs. In some examples described herein, the sequences are repeated at least 2 times. In some examples, the sequences are repeated at least 5 times, at least 10 times, at least 15 times, at least 20 times, at least 25 times, at least 30 times, at least 35 times, at least 40 times, at least 45 times, at least 50 times, at least 100 times, or more. It is a type of variable number tandem repeat (VNTR). SSRs are typically co-dominant.

The term "unique-event polymorphism (UEP)", as used herein, refers to a genetic marker that corresponds to an allele for which all copies derive from a single mutational event. This mutational event makes is possible for this marker to act as a global marker, indicating that the prevalence of this marker in the DNA of two individuals indicates a high likelihood of both these individuals being descendent from the same common ancestor, and/or the same single mutation event.

As used herein, the term "insertion or deletions (INDELs)" refers to the presence of an insertion or a deletion of one or more nucleotides within a nucleic acid sequence compared to a related nucleic acid sequence. An insertion or a deletion therefore includes the presence or absence of a unique nucleotide or nucleotides in one nucleic acid sequence compared to an otherwise identical nucleic acid sequence at adjacent nucleotide positions.

The term "associated with" or "associated," when referring to a nucleic acid (e.g., a genetic marker) and a phenotype in the context of the present invention, refers to a nucleic acid and a phenotypic trait that are in linkage phase disequilibrium. The term

"linkage phase disequilibrium" or "linkage disequilibrium" refers to a non-random segregation of genetic loci, i.e. the preferential association of a particular allele or genetic marker with a specific allele, or genetic marker at a nearby locus that is more frequently than expected by chance for any particular allele frequency in the population. For example, if locus X has alleles A and B, which occur equally frequently, and linked locus Y has alleles C and D, which occur equally frequently, one would expect the combination AC to occur with a frequency of 0.25. If AC occurs more frequently, then alleles A and C are in linkage disequilibrium. This implies that such loci are in sufficient physical proximity along a length of a chromosome that they tend to segregate together with greater than random frequency. The term "locus", as used herein, refers to a specific chromosome location in the genome of a species where a specific gene can be found. The term "genetically linked" refers to genetic loci, including genetic marker loci, which are physically close enough to each other on the same chromosome, so that they have a recombination frequency of less than 0.5. A "genotype" is the genetic constitution of an individual (or group of individuals) at one or more genetic loci. Genotype is defined by the allele(s) of one or more known loci that the individual has inherited from its parents. An individual is "homozygous" if the individual has only one type of allele at a given locus (e.g., a diploid individual with two copies of the same allele at a locus). An individual is "heterozygous" if more than one allele type is present at a given locus (e.g., a diploid individual with one copy each of two different alleles). The term "homogeneity" indicates that members of a group have the same genotype at one or more specific loci. In contrast, the term "heterogeneity" is used to indicate that individuals within the group differ in genotype at one or more specific loci.

The term "oligonucleotide" as used herein refers to short nucleic acid molecules useful, for example, as hybridizing probes, nucleotide array elements or amplification primers. Oligonucleotide molecules are comprised of two or more nucleotides, i.e. deoxyribonucleotides or ribonucleotides, preferably more than five and up to 30 or more. The exact size will depend on many factors, which in turn depend on the ultimate function or use of the oligonucleotide. Oligonucleotides can comprise ligated natural nucleic acid molecules or synthesized nucleic acid molecules and comprise between 10 to 150 nucleotides or between about 12 and about 100 nucleotides which have a nucleotide sequence which can hybridize to a strand of polymorphic DNA, e.g. to permit detection of a polymorphism. Such oligonucleotides may be nucleic acid elements for use on solid arrays (e.g. synthesized or spotted). In some examples of the invention, such oligonucleotides can comprise as few as 12 hybridizing nucleotides, e.g. for assays where the oligonucleotide also comprises a detectable label. In other examples of the invention, the oligonucleotide can comprise as few as about 15 hybridizing nucleotides, e.g. for single base extension assays. Such oligonucleotides may also be primers for use in polymerase chain reaction (PCR) or other reactions.

The term "primer" as used herein refers to a nucleic acid molecule, preferably an oligonucleotide, whether derived from a naturally occurring molecule such as one isolated from a restriction digest or one produced synthetically, which is capable of acting as a point of initiation of synthesis when placed under conditions in which synthesis of a primer extension product which is complementary to a nucleic acid strand is induced, i.e., in the presence of nucleotides and an agent for polymerization such as DNA polymerase and at a suitable temperature and pH. The primer is preferably single stranded for maximum efficiency in amplification, but may alternatively be double stranded. If double stranded, the primer is first treated to separate its strands before being used to prepare extension products. Preferably, the primer is an oligodeoxyribonucleotide. The primer must be sufficiently long to prime the synthesis of extension products in the presence of the agent for polymerization. The exact lengths of the primers will depend on many factors according to the particular application, including temperature and source of primer. For example, depending on the complexity of the target sequence, the oligonucleotide primer typically contains at least 15, more preferably 18 nucleotides, which are identical or complementary to the template and optionally a tail of variable length which need not match the template. The length of the tail should not be so long that it interferes with the recognition of the template. Short primer molecules generally require cooler temperatures to form sufficiently stable hybrid complexes with the template.

The primers herein are selected to be "substantially" complementary to the different strands of each specific sequence to be amplified. This means that the primers must be sufficiently complementary to hybridize with their respective strands. Therefore, the primer sequence need not reflect the exact sequence of the template. For example, a non-complementary nucleotide fragment may be attached to the 5' end of the primer, with the remainder of the primer sequence being complementary to the strand. Alternatively, non-complementary bases or longer sequences can be interspersed into the primer, provided that the primer sequence has sufficient complementarity with the sequence of the strand to be amplified to hybridize therewith and thereby form a template for synthesis of the extension product of the other primer. Computer generated searches using programs such as Primer3 (www-genome. wi.mit.edu/cgi- bin/primer/primer3.cgi), STSPipeline (www-genome, wi.mit.edu/cgi-bin/www- STS_Pipeline), or GeneUp, for example, can be used to identify potential PCR primers. Exemplary primers include primers that are 18 to 50 bases long, where at least between 18 bases are identical or complementary to at least 18 bases of a segment of the template sequence. In some examples described herein, primers that are 20 bases long are used.

This invention also contemplates and provides primer pairs for amplification of nucleic acid molecules in order to detect polymorphisms. As used herein "primer pair" means a set of two oligonucleotide primers based on two separated sequence segments of a target nucleic acid sequence. One primer of the pair is a "forward primer" or "5' primer" having a sequence which is identical to the more 5' of the separated sequence segments (+ strand). The other primer of the pair is a "reverse primer" or "3 ' primer" having a sequence which is the reverse complement of the more 3 ' of the separated sequence segments (- strand). A primer pair allows for amplification of the nucleic acid sequence between and including the separated sequence segments. Optionally, each primer pair can comprise additional sequences, e.g. universal primer sequences or restriction endonuclease sites, at the 5' end of each primer, e.g. to facilitate cloning, DNA sequencing, or re-amplification of the target nucleic acid sequence.

As used herein, the terms "increase" and "decrease" refer to the relative alteration of a chosen trait or characteristic in a subset of a population in comparison to the same trait or characteristic as present in the whole population. An increase thus indicates a change on a positive scale, whereas a decrease indicates a change on a negative scale. The term "change", as used herein, also refers to the difference between a chosen trait or characteristic of an isolated population subset in comparison to the same trait or characteristic in the population as a whole. However, this term is without valuation of the difference seen.

As used in this application, the singular form "a," "an," and "the" include plural references unless the context clearly dictates otherwise. For example, the term "a genetic marker" includes a plurality of genetic markers, including mixtures and combinations thereof.

The word "substantially" does not exclude "completely" e.g. a composition which is "substantially free" from Y may be completely free from Y. Where necessary, the word "substantially" may be omitted from the definition of the invention. As used herein, the term "about", in the context of concentrations of components of the formulations, typically means +/- 5% of the stated value, more typically +/- 4% of the stated value, more typically +/- 3% of the stated value, more typically, +/- 2% of the stated value, even more typically +/- 1 % of the stated value, and even more typically +/- 0.5% of the stated value.

Throughout this disclosure, certain embodiments may be disclosed in a range format. It should be understood that the description in range format is merely for convenience and brevity and should not be construed as an inflexible limitation on the scope of the disclosed ranges. Accordingly, the description of a range should be considered to have specifically disclosed all the possible sub-ranges as well as individual numerical values within that range. For example, description of a range such as from 1 to 6 should be considered to have specifically disclosed sub-ranges such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6 etc., as well as individual numbers within that range, for example, 1, 2, 3, 4, 5, and 6. This applies regardless of the breadth of the range.

Certain embodiments may also be described broadly and generically herein. Each of the narrower species and sub-generic groupings falling within the generic disclosure also form part of the disclosure. This includes the generic description of the embodiments with a proviso or negative limitation removing any subject matter from the genus, regardless of whether or not the excised material is specifically recited herein.

The invention illustratively described herein may suitably be practiced in the absence of any element or elements, limitation or limitations, not specifically disclosed herein. Thus, unless specified otherwise, the terms "comprising," "including," and

"containing," and grammatical variants thereof, are intended to represent "open" or "inclusive" language such that they include recited elements but also permit inclusion of additional, un-recited elements. Additionally, the terms and expressions employed herein have been used as terms of description and not of limitation, and there is no intention in the use of such terms and expressions of excluding any equivalents of the features shown and described or portions thereof, but it is recognized that various modifications are possible within the scope of the invention claimed. Thus, it should be understood that although the present invention has been specifically disclosed by preferred embodiments and optional features, modification and variation of the inventions embodied therein herein disclosed may be resorted to by those skilled in the art, and that such modifications and variations are considered to be within the scope of this invention. Other embodiments are within the following claims and non- limiting examples. In addition, where features or aspects of the invention are described in terms of Markush groups, those skilled in the art will recognize that the invention is also thereby described in terms of any individual member or subgroup of members of the Markush group.

BRIEF DESCRIPTION OF THE DRAWINGS

The accompanying drawings illustrate a disclosed embodiment and serves to explain the principles of the disclosed embodiment. It is to be understood, however, that the drawings are designed for purposes of illustration only, and not as a definition of the limits of the invention.

Fig. 1 shows the results of the phylogenetic analysis of the MYB genes. These results suggested that the shortlisted candidate MYB genes play a role in regulating fruit colour in the oil palm exocarp.

Fig. 2 shows a diagram depicting the marker accuracy in a haplotype region, which contains the MYB genes putatively linked to the virescens (Vir) trait. The location of the genes MYB001, MYB002 and MYB003 are shown in the diagram. A haplotype block sequence linked to MYB002 comprising 2,533,421 base pairs with markers that provide 100% accuracy is also shown in the diagram.

DISCLOSURE OF OPTIONAL EMBODIMENTS

Exemplary, non-limiting embodiments of a method of predicting or determining fruit exocarp trait (such as fruit exocarp colour) of oil palm fruits, will now be disclosed.

Fruits changes colour during the ripening process. In the oil palm fruit bunch, this change of colour can be utilised as an indication of ripeness of the fruit before harvesting. The present disclosure describes a set of genetic markers that can be used individually or in combinations to predict or determine the fruit exocarp colour of oil palm fruits. Early prediction, or determination, of not yet visually discernible fruit exocarp colour aids the selection of plants having the desired fruit exocarp colour, for example, for use in producing hybrids and/or for use in breeding programs (e.g. screening of germpalsm collections for plants that may be suitable for inclusion in breeding programs). For example, due to the dramatic change of colour from green to orange-red, it is easier to determine if virescens bunches are ready to be harvested, compared to nigrescens bunches. Therefore, if it is desired that plants be selected to facilitate the harvesting process and avoid harvesting under-ripe or over-ripe fruit bunches, plants having the virescens trait may be selected (which would bear fruits exhibiting the dramatic colour change) by detecting the presence or absence of one or more genetic markers associated with the virescens trait. Alternatively, as the variation in fruit colour also reflects the carotenoid content, with the nigrescens fruit type containing more carotenoid than the virescens fruit type, plants having the nigrescens trait may be selected to obtain fruits having higher carotenoid content by detecting the presence or absence of one or more genetic markers associated with the nigrescens trait. Advantageously, the early prediction, or determination, of fruit exocarp colour facilitates breeding by enabling screening to be carried out at an earlier stage and increases the precision by which predictions on traits can be made, thus shortening cycle time and reducing the cost of breeding programs. For example, in practice, after breeding, the method disclosed herein can be used for testing progeny plants to see if they would exhibit the selected fruit exocarp trait by taking a sample from the plant, analysing for the presence or absence of polymorphic genetic markers and comparing those markers to previously identified markers and their known fruit exocarp trait, and making a prediction if this particular plant will exhibit the desired fruit exocarp trait during growth or at maturity.

In some examples, there is described a method of predicting fruit exocarp trait of an oil palm plant not yet visually detectable for screening and selection of plants possessing the exocarp trait of interest to be planted or bred with other plants of the same species using polymorphic markers obtained in the method described herein. In other words, the method allows anticipating the exocarp trait of interest without having to wait until the traits is visually detectable or measurable. Advantageously, by being able to predict the exocarp trait by determining the plant genotype, the inventors, and plant breeders, are able to save time and costs. An example of a method for predicting or determining a plant genotype of interest may include, but is not limited to, the following steps, starting with taking a sample of an oil palm plant, seed or sapling to be analysed. This genetic analysis of the plant would show, for example, which marker or markers are present and where. The result of this type of genetic analysis or mapping for this sample may then be compared with a list of known markers, which had previously been correlated with one or more exocarp traits for the oil palm plant. Thus, this comparison between the genetic analysis of the sample and the list of known markers would be able to infer a statistical probability with which the tested plant would display the desired exocarp trait upon maturity. In order for this to be possible, at least one marker must be present in the sample. As used herein, the term "predicting" or "prediction" is defined as to state, or make something known in advance, especially using inference or special knowledge. In the context of the present disclosure for example, this means that with the knowledge available to a person skilled in the art with regards to the location and amount of polymorphic genetic markers in the oil palm plant, the person skilled in the art would be able to predict if an oil palm plant being tested would show the deduced phenotype (i.e. fruit exocarp colour) upon maturity. As used herein, the term "determining" or "determination" in defined as ascertaining or establishing something exactly by research or calculation. In this case, the determination of the fruit exocarp trait or colour of interest is a direct result of the genetic analysis performed on a plant sample. In some examples, there is disclosed the method as previously described, wherein the oil palm is of the genus Elaeis. In another example, the genus may consist of the forms dura (e.g. Nigerian dura) and tenera (e.g. Nigerian tenera, Angola tenera etc.). In another example, the genus may consist of the variation pisifera (e.g. AVROS pisifera). A breeder of ordinary skill, desiring to breed oil palm plants with a particular fruit exocarp trait, can apply the methods as described herein, using, e.g., the exemplary markers described herein or linked markers localized to the chromosome segments identified by markers listed in Tables 3 to 9 below, or any other markers that may be present within SEQ ID NO: 13295 or alternatively SEQ ID NOs: 13020 to 13294, to derive oil palm lines with the desired fruit exocarp trait.

Genetic marker alleles, linked markers, identifying the chromosome segments encompassing genetic elements that are important for fruit exocarp trait (in particular, colour), are used to identify oil palm plants that contain a desired genotype at one or more loci, and that are expected to transfer the desired genotype, along with the desired phenotype (i.e. fruit exocarp trait) to their progeny. Marker alleles can be used to identify plants that contain a desired genotype at one locus, or at several unlinked or linked loci (e.g., a haplotype), and that would be expected to transfer the desired genotype, along with the desired phenotype to their progeny. Similarly, by identifying plants lacking the desired allele, plants with an undesirable phenotype (e.g. plants with the nigrescens trait if the aim is to obtain fruit bunches with easily detectable colour changes from the unripe stage to the ripe stage, or plants with the virescens trait if the aim is to obtain fruits with higher carotenoid content) can be eliminated from subsequent crosses.

After a desired phenotype and a polymorphic chromosomal locus, e.g. a marker locus, are determined to segregate together (i.e. are determined to be in linkage disequilibrium), alleles corresponding to the desired phenotype are selected. In brief, a nucleic acid corresponding to the marker nucleic acid is detected in a biological sample from a plant to be selected. This detection can take the form of hybridization of a probe nucleic acid to a marker, e.g. using allele- specific hybridization, Southern analysis, Northern analysis, in situ hybridization, hybridization of primers followed by PCR amplification of a product including the marker, or the like. After the presence (or absence) of a particular marker in the biological sample is verified, the plant is selected and, optionally, crossed to produce progeny plants.

In one example, there is disclosed a method of predicting or determining fruit exocarp trait of an oil palm fruit, the method comprising detecting the presence or absence of one or more genetic markers located in Haplotype Block A, wherein Haplotype Block A comprises or consists of SEQ ID NO: 13295 or alternatively SEQ ID NOs: 13020 to 13294. It is believed that the Haplotype Block A is associated with a genetic region of the oil palm genome that regulates fruit exocarp colour in oil palm. In one example, the genetic marker located in the Haplotype Block A is selected from a group consisting of SEQ ID NOs: 1 to 12767, the markers listed in Table 3 and the markers listed in Table 9.

In a further example, the Haplotype Block A comprises Haplotype Block B (comprising of base pair 165670 to base pair 6925842 of SEQ ID NO: 13295 or comprising of base pair 18836 of SEQ ID NO: 13029 to base pair 158067 of SEQ ID NO: 13256 ). In one example, the Haplotype Block B comprises a genetic marker selected from a group consisting of SEQ ID NOs: 11 to 9172. In one example, the Haplotype Block B comprises a genetic marker selected from a group consisting of the markers listed in Table 4. In one example, the Haplotype Block B comprises a genetic marker selected from a group consisting of the markers listed in Table 3.

In one example, the Haplotype Block B comprises a genetic marker selected from a group consisting of SEQ ID NO: 11, SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID NO: 4903, SEQ ID NO:

4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, SEQ ID NO: 4909, SEQ ID NO: 4910, SEQ ID NO: 4911, SEQ ID NO: 4912, SEQ ID NO: 4913, SEQ ID NO: 4914, SEQ ID NO: 9168, SEQ ID NO: 9169, SEQ ID NO: 9170, SEQ ID NO: 9171, SEQ ID NO: 9173, SEQ ID NO: 9174, SEQ ID NO: 9175, SEQ ID NO: 9176, SEQ ID NO: 9177, SEQ ID NO: 9178, SEQ ID NO: 9179, SEQ ID NO: 9180, SEQ ID NO: 9181, SEQ ID NO: 9182, SEQ ID NO: 9183, and SEQ ID NO: 9184. In another example, the Haplotype Block B comprises a gene selected from a group consisting of MYBOOl (SEQ ID NO: 12891), MYB002 (SEQ ID NO: 12892) and MYB003 (SEQ ID NO: 12893), or a variant thereof having more than 70%, 80%, 90%, 95%, 98% or 99% sequence identity to one of SEQ ID NOs: 12891 to 12893. In one example, the gene MYBOOl (SEQ ID NO: 12891) comprises the genetic marker of SEQ ID NO: 11. In one example, the gene MYB002 (SEQ ID NO: 12892) comprises a genetic marker selected from a group consisting of SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID NO: 4903, SEQ ID NO: 4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, and SEQ ID NO: 4909.

In a yet further example, the Haplotype Block B comprises Haplotype Block C (comprising of base pair 3208714 to 5742135 of SEQ ID NO: 13295 or comprising of base pair 39774 of SEQ ID NO: 13123 to base pair 21091of SEQ ID NO: 13215). In one example, the Haplotype Block C comprises a genetic marker selected from a group consisting of SEQ ID NOs: 2860 to 6898. In one example, the Haplotype Block C comprises a genetic marker selected from a group consisting of the markers listed in Table 4. In one example, the Haplotype Block C comprises a genetic marker selected from a group consisting of the markers listed in Table 3.

In one example, the Haplotype Block C comprises a genetic marker selected from a group consisting of SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID NO: 4903, SEQ ID NO: 4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, SEQ ID NO: 4909, SEQ ID NO: 4910, SEQ ID NO: 4911, SEQ ID NO: 4912, SEQ ID NO: 4913, and SEQ ID NO: 4914. In one example, the Haplotype Block C comprises the gene MYB002 (SEQ ID NO: 12892), or a variant thereof having more than 70%, 80%, 90%, 95%, 96%, 97%, 98% or 99% sequence identity to SEQ ID NO: 12892. In one example, the gene MYB002 (SEQ ID NO: 12892) comprises a genetic marker selected from a group consisting of SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID NO: 4903, SEQ ID NO: 4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, and SEQ ID NO: 4909.

In one example, the genetic marker is SEQ ID NO: 4901.

In one example, the genes MYB001 (SEQ ID NO: 12891), MYB002 (SEQ ID NO: 12892) and MYB003 (SEQ ID NO: 12893) each encodes a transcription factor. In one example, the transcription factor comprises SEQ ID NO: 12894, SEQ ID NO: 12895 and SEQ ID NO: 12896, or a variant thereof having more than 70%, 80%, 90%, 95%, 96%, 97%, 98% or 99% sequence identity to one of SEQ ID NOs: 12894 to 12896. SEQ ID NO: 12894 refers to the amino acid sequence of MYB001 as encoded by SEQ ID NO: 12891. SEQ ID NO: 12895 refers to the amino acid sequence of MYB002 as encoded by SEQ ID NO: 12892. SEQ ID NO: 12896 refers to the amino acid sequence of MYB003 as encoded by SEQ ID NO: 12893. In one example, the transcription factor comprises a MYB DNA binding domain. In another example, there is disclosed a method of predicting or determining a fruit exocarp trait of an oil palm fruit, wherein the method comprises detecting the presence or absence of a one or more genetic marker (e.g. a polymorphic genetic marker) including, but not limited to SEQ ID NOs: 1 to 12767 and Tables 3 and 4. In another example, the method comprises detecting the presence or absence of two or more, three or more, four or more, five or more, six or more, seven or more, eight or more, nine or more, ten or more, or eleven or more, or all polymorphic genetic marker(s) including, but not limited to SEQ ID NOs: 1 to 12767 and Tables 3 and 4. In another example, the method comprises detecting the presence or absence of two or more, three or more, four or more, five or more, six or more, seven or more, eight or more, nine or more, ten or more, or eleven or more, or all polymorphic genetic marker(s) including, but not limited to SEQ ID NO: 1 1, SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID NO: 4903, SEQ ID NO: 4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, SEQ ID NO: 4909, SEQ ID NO: 4910, SEQ ID NO: 4911, SEQ ID NO: 4912, SEQ ID NO: 4913, SEQ ID NO: 4914, SEQ ID NO: 9168, SEQ ID NO: 9169, SEQ ID NO: 9170, SEQ ID NO: 9171, SEQ ID NO: 9173, SEQ ID NO: 9174, SEQ ID NO: 9175, SEQ ID NO: 9176, SEQ ID NO: 9177, SEQ ID NO: 9178, SEQ ID NO: 9179, SEQ ID NO: 9180, SEQ ID NO: 9181, SEQ ID NO: 9182, SEQ ID NO: 9183, and SEQ ID NO: 9184. In another example, the method comprises detecting the presence or absence of two or more, three or more, four or more, five or more, six or more, seven or more, eight or more, nine or more, ten or more, or eleven or more, or all polymorphic genetic marker(s) including, but not limited to SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID NO: 4903, SEQ ID NO: 4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, SEQ ID NO: 4909, SEQ ID NO: 4910, SEQ ID NO: 4911, SEQ ID NO: 4912, SEQ ID NO: 4913, and SEQ ID NO: 4914. In another example, the method comprises detecting the presence or absence of two or more, three or more, four or more, five or more, six or more, seven or more, eight or more, nine or more, ten or more, or eleven or more, or all polymorphic genetic marker(s) including, but not limited to SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID NO: 4903, SEQ ID NO: 4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, and SEQ ID NO: 4909.

In one example, the fruit exocarp colour is a trait selected from the group consisting of Nigrescens and Virescens. In one example, the fruit exocarp colour traits of Nigrescens and Virescens are mutually exclusive. In one example, the Nigrescens fruit colour may be referred to as "Nigrescens Black" in its unripe stage, and as "Nigrescens Ripe" in its ripe stage. In one example, the Virescens fruit colour may be referred to as "Virescens Green" in its unripe stage, and as "Virescens Ripe" in its ripe stage. In one example, the disclosed method comprises the step of determining that at least one, or all genetic markers, selected from a group consisting of SEQ ID NO: 1 to 12767 are indicative of the fruit exocarp colour trait of Virescens. In one example, the disclosed method comprises the step of determining that at least one, or all genetic markers, selected from a group consisting of SEQ ID NO: 11, SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID NO: 4903, SEQ ID NO: 4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, SEQ ID NO: 4909, SEQ ID NO: 4910, SEQ ID NO: 4911, SEQ ID NO: 4912, SEQ ID NO: 4913, SEQ ID NO: 4914, SEQ ID NO: 9168, SEQ ID NO: 9169, SEQ ID NO: 9170, SEQ ID NO: 9171, SEQ ID NO: 9173, SEQ ID NO: 9174, SEQ ID NO: 9175, SEQ ID NO: 9176, SEQ ID NO: 9177, SEQ ID NO: 9178, SEQ ID NO: 9179, SEQ ID NO: 9180, SEQ ID NO: 9181, SEQ ID NO: 9182, SEQ ID NO: 9183, and SEQ ID NO: 9184 are indicative of the fruit exocarp colour trait of Virescens.

In one example, the disclosed method comprises the step of determining that at least one, or all genetic markers, selected from a group consisting of Table 4 are indicative of the fruit exocarp colour trait of Virescens.

In one example, the disclosed method comprises the step of determining that at least one, or all genetic markers, selected from a group consisting of Table 3 are indicative of the fruit exocarp colour trait of Virescens.

In one example, the alleles at the positions listed in Tables 5 to 7 may be used as an indication of the fruit exocarp colour trait of Virescens; see Example 6 below. For example, by comparing a sequence obtained from a plant sample against the genotypes listed in Tables 5 to 7, it may be determined if the plant from which the plant sample is obtained would have the Virescens trait or the Nigrescen trait. In some examples, the

Virescens genotype may be Virescen genotype 1 or Virescen genotype 2.

It will be appreciated that plants positive for a marker of the invention, can be selected and crossed according to any breeding protocol relevant to the particular breeding program. Accordingly, progeny can be generated from a selected plant by crossing the selected plant to one or more additional plants selected on the basis of the same marker or a different marker, e.g. a different marker correlating with superior agronomic performance, or a different phenotype of interest, e.g., resistance to a particular disease. Alternatively, a selected plant can be back crossed to one or both parents.

The term "crossed" or "cross" in the context of this disclosure means the fusion of gametes, e.g. via pollination to produce progeny (i.e. cells, seeds, or plants). The term encompasses both sexual crosses (the pollination of one plant by another) and selfing (self-pollination, i.e. when the pollen and ovule are from the same plant).

A selected plant may be backcrossed, e.g. with one of its parents or an individual genetically similar to its parent. Backcrossing is usually done for the purpose of introgressing one or a few loci from a donor parent, into an otherwise desirable genetic background from the recurrent (typically, an elite) parent. The more cycles of backcrossing that are performed, the greater is the genetic contribution of the recurrent parent to the resulting variety. A selected plant can also be outcrossed, e.g. to a plant or line not present in its genealogy. Such a plant can be selected from among a population subject to a prior round of analysis, or may be introduced into the breeding program de novo. A plant positive for a desired marker can also be self-crossed ("selfed") to create a true breeding line with the same genotype.

In some examples, the method is as described herein, wherein the genetic markers are polymorphic markers from oil palms.

In one example, the genetic marker is selected from a group consisting of single nucleotide polymorphism (SNP), simple sequence repeats (SSRs), insertion or the deletion of bases (INDel), unique-event polymorphism (UEP) and short tandem repeat (STR). In the examples described herein, the markers used for the disclosed method are single nucleotide polymorphism (SNP) markers, simple sequence repeats (SSRs), insertion or the deletion of bases (INDel) and combinations thereof, but the method can be applied to any genetic markers familiar to the person skilled in the art. In some examples, the genetic marker is a single nucleotide polymorphism (SNP) or simple sequence repeats (SSRs). In some examples, the genetic marker is a SNP selected from a group consisting of SEQ ID NOs: 1 to 12767 and/or the markers listed in Table 10. In some other examples, the genetic marker is a SSR selected from a group consisting of SEQ ID NOs: 12768 to 12830. In yet other examples, the genetic marker is an INDEL selected from a group consisting of SEQ ID NOs: 12831 to 12890 and/or the markers listed in Table 3.

In one example, a plurality of the genetic markers is inherited as a haplotype. As used herein, the term "plurality" refers to at least 2, e.g. at least 5, at least 10, at least 20, at least 50, at least 100, at least 500, at least 1,000, at least 5,000 or at least 10,000 or more, up to 12,890, or more.

In one example of the disclosed method, the detecting of the presence or absence of one or more genetic marker is conducted on a plant or a plant sample containing genetic material (e.g. nucleic acid, DNA, RNA, etc.) and/or proteinaceous material (e.g. protein). In one example, the plant sample is selected from a group consisting of leaves, spear leaves, stem, saplings, roots, buds, flowers, seed, fruit, and parts thereof.

In one example, the presence or absence of one or more genetic markers is determined in a plant sample containing genetic material. Development of the genetic markers for use in the disclosed method may be facilitated by genotyping, gene sequencing and transcriptome sequencing -based methods. Transcriptome analysis (or determination of transcript abundance) is typically performed on tissue samples from the plant. Any part of the plant containing RNA transcripts may be used. For example, the tissue sample may be taken from the aerial parts, seed, leaf, stem, root, bud, flower, or fruit of the plant.

The plant sample may be obtained from a population of oil palm, which may comprise a population of oil palm having different genetic background. For example, a population of oil palm may comprise, but is not limited to, breeding populations of restricted origins (BPRO) such as AVROS, Deli, Yangambi, Cameroon, Ekona, Calabar and combinations thereof. The population may be selected according to its structure, owing to geography, natural selection or artificial selection.

In one example, the plant sample is obtained from a population of oil palm generated through a selfing of a virescens Nigerian tenera oil palm (Population A). In another example, the plant sample is obtained from a population of oil palm generated through a cross between a Nigerian dura and an AVROS pisifera (Population B). In yet another example, the plant sample is obtained from a population of oil palm generated through a selfing of an Angola tenera oil palm (Population C).

In some examples, a method is described, wherein plant material used for identifying genetic (e.g. polymorphic) markers is obtained from at least two, at least three, or at least four or more different plant populations of the same species with different genetic backgrounds. Advantageously, the inventors found that with the inclusion of different genetic backgrounds, the ability of the analysis to discern markers linked to traits is enhanced. Various techniques are available for transcriptome analysis, and any suitable technique may be used for the purpose of the present disclosure. For example, transcriptome analysis may be performed using hybridization- or sequence-based approaches. Hybridization-based approaches typically involve incubating fluorescently labelled cDNA with custom-made microarrays or commercial high-density oligo microarrays. Sequence-based approaches directly determine the cDNA sequence, and utilize technologies such as Sanger sequencing of cDNA or EST libraries.

Typically, transcriptome analysis is performed on RNA extracted from the plant tissue sample. Any suitable methods of RNA extraction known in the art may be used, e.g. see the protocol set out in the Examples. Any suitable modifications to the disclosed methods that are known to a person skilled in the art are also contemplated herein.

In one example using transcriptome analysis, three genes coding for MYB are found in the Applicants' proprietary oil palm reference genome, which are found to be highly expressed in Nigrescens Black but lowly expressed in Nigrescens Ripe, Virescens

Green and Virescens Ripe. In one example, the three MYB genes are MYB001 (SEQ ID NO: 12891), MYB002 (SEQ ID NO: 12892) and MYB003 (SEQ ID NO: 12893) as described above. Phylogenetic analysis may be used to determine the evolutionary relationships of the MYB genes. Phylogenetic trees may be drawn up using available programs such as the CLUSTALW program, preferably version 1.83 (available at http://align.genome.jp). In one example, the three MYB genes are shown by the phylogenetic analysis to be part of the same gene cluster as those that are involved in the anthocyanin biosynthesis pathway of plants.

Target capture sequencing may be applied to the region spanning the three MYB genes, for example using hybridizing capture probes to capture genomic DNA of interest. Capture kits with oligonucleotides probes are available, e.g. from Roche NimbleGenSeqCap EZ, Agilent SureSelect and Illumina TruSeq capture. Captured DNA is adapted to generate a library that is then sequenced, e.g. using Ilumina HiSeq2000 or other platforms as appropriate, to typically generate paired end 2 x lOObp sequence reads resulting in 50-100x coverage. The generated sequence data is then analyzed, after quality control filtering, for example using the Applicants' proprietary oil palm reference genome (or any other appropriate reference genomes) for variant calling and annotation. In one example, the target region is Haplotype Block A (SEQ ID NO: 13295 or SEQ ID NOs: 13020 to 13294).

Once a map of the target region is constructed (using techniques known and available in the art), genetic markers (e.g. polymorphic markers) that may be useful for predicting or determining fruit exocarp colour may be "mined." The genetic markers include, but are not limited to, single nucleotide polymorphism (SNP), simple sequence repeats (SSRs), insertion or the deletion of bases (INDel), unique-event polymorphism (UEP) and short tandem repeat (STR). The genetic markers mined may be genotyped. The term "genotyping", as used herein, refers to any type of analysis of a nucleic acid sequence, and includes sequencing, polymorphism (e.g. SNP) analysis, and analysis to identify rearrangements.

"Genotyping a sample," for example, refers to determining a specific allele or specific rmcleotide(s) in a sample at particular region(s). In one example, genotyping refers to methods to determine which alleles at one or several DNA sequence polymorphisms are present in the analyzed samples. Several methods to genotype DNA sequence polymorphisms are available and well known in the art, including quantitative genotyping methods, which can be applied in the present disclosure. One commonly used method to genotype large numbers of SNP in parallel relies on SNP genotyping arrays, e.g. commercially available arrays from by Illumina Inc.

Accuracy plots, e.g. in the form of box-whisker plots, may be constructed to reveal the distributions of testing accuracy and number of predictive markers. An example is shown in Fig, 2 as described below. The sequencing of a nucleic acid sample (i.e. determining the nucleotide order of a given DNA or RNA fragment) is not limited to any one technique. The present disclosure contemplates the use of any sequencing technique known in the art, e.g. Sanger sequencing. The Sanger sequencing process can be automated using a DNA sequencer, such as those commercially available from PerkinElmer, Beckraan Coulter, Life Technologies, and others. "Next-generation sequencing" techniques as described above may also be used. In one example, there is provided a method for selecting an oil palm plant for breeding, comprising using one or more genetic marker as disclosed herein, wherein the selection is based on the presence or absence of the genetic marker within a Haplotype Block as disclosed herein. In one example, there is provided the use of one or more genetic markers as disclosed herein as criteria for the selection of an oil palm plant, wherein the selection is based on the presence or absence of one or more of the disclosed genetic markers.

The practice of the present disclosure will employ, unless otherwise indicated, conventional techniques of molecular biology, microbiology, and recombinant DNA technology which are within the skill of those working in the art. Such techniques are explained fully in the literature. Examples of texts for consultation include "Molecular Cloning: A Laboratory Manual" (Fourth Edition, 2012) by Michael R. Green, Howard Hughes Medical Institute, University of Massachusetts Medical School; Joseph Sambrook, Peter MacCallum Cancer Institute, Melbourne, Australia.

EXAMPLES

Non-limiting examples of the invention, including the best mode, and a comparative example will be further described in greater detail by reference to specific Examples, which should not be construed as in any way limiting the scope of the invention.

The Applicants' proprietary oil palm genome was queried and the contiguous genomic region in one of the assembled scaffolds was identified to contain known markers linked to the fruit type colour controlling gene. Based on the hypothesis that certain genes that perform similar functions and are related to each other have a tendency to cluster together, and that the known markers would be in linkage disequilibrium with the actual causative sequence, this region was analyzed. The analysis showed that this region contains structural motives similar to known basic helix-loop-helix (bHLH), WD-40/beta-transducin repeat (WD) and MYB that are related to anthocyanin genes.

As these transcription factors have been reported to play an important role in fruit colour regulation in other plants, they were studied in more detail to ascertain their relationship to the fruit colour trait and to determine if there are any sequences therein that are directly responsible for controlling the fruit colour trait of interest. Genotyping, gene sequencing and transcriptome sequencing based methods were used to identify and determine the three transcription factors (MYB) that are linked to the fruit colour determination trait. The region where the three MYB transcription factors are located in is in a contiguous region of DNA sequence in the Applicant' s proprietary oil palm reference genome. Markers were used to assay the region, and the accuracy of the markers in predicting the presence of the virescens trait was determined and correlated with the actual phenotype observed in oil palm populations in order to determine the accuracy of prediction. The inventors also showed that the region is in linkage disequilibrium and exists in a form of a haplotype block spanning 2.5Mbps (Haplotype block C). Markers within this haplotype block (Haplotype block C) can provide prediction accuracies of up to 100%. Accordingly, the haplotype block can be used to distinguish between genetic materials that will code for the virescens trait and the genetic materials that will code for the nigrescens trait. A person skilled in the art will appreciate that the haplotype block itself will contain many sequences that can be used as markers and since the region is strongly associated with the trait, even sequences that have not been identified as markers in the following examples can be used to predict the virescens trait. The 2.5Mbps haplotype block region was also shown to contain the MYB002 transcription factor, where a SNP that has 100% accuracy in all oil palm populations tested is present. The 2.5Mbps haplotype block region was also shown to produce a SNP that could be the causative SNP that controls the virescens trait.

EXAMPLE 1: POPULATIONS USED

For this experiment, two populations of oil palm that segregated for the fruit colour trait were used. The first population, Population A, consisted of 82 progeny palms from the selfing of a virescens Nigerian, background tenera, oil palm. A second population, Population B, consisted of 141 palms generated through a Nigerian dura x AVROS pisifera cross, while a third population, Population C, consisted of 37 progeny palms from the selfing of an Angola, background tenera, oil palm. Table 1 provides more information pertaining to the number of nigrescens and virescens plants and the background of each population. Table 1 : Populations Used to Study the Fruit Colour Trait

EXAMPLE 2: TRANSCRIPTOME DATA

Total RNA was extracted using methods known in the art in triplicates for each of the following stages of ripeness of the two different fruit colour type; unripe nigrescens, ripe nigresence, unripe virescens and unripe virescens. Total RNA extraction was carried out using modified McCarty 1986 (McCarty, DR (1986) A simple method for extraction of RNA from maize tissues; MNL 60:61). Total RNA was extracted from three independent exocarp of undamaged fruits and the mesocarp were cut into thin slices, and submerged in liquid nitrogen using the phenol-chloroform method. A total of 2 g of small tissue pieces were ground into fine powder in the presence of liquid nitrogen and the powder was then transferred into a 50 ml Falcon tube containing the mixture of lysis solution and phenol/chloroform. The sample was then vortexed vigorously and centrifuged for 20 minutes at 10,000 rpm. The supernatant was then extracted and mixed with an equal volume of phenol/chloroform, followed by addition of 0.1 times the original supernatant volume of 3 M NaOAc and 2 times the volume of the original supernatant volume of 100 % EtOH precipitation. After centrifugation, RNA pellets were washed by 70% ethanol and precipitated with lithium chloride twice. The RNA samples were further purified by RNA clean up kit (Qiagen). Subsequently, RNA quantity and purity was assessed using NanoDrop spectrophotometer (NanoDrop Technologies) and gel electrophoresis. The total RNA was quantified, quality checked and sequenced using the Illumina HiSeq2000 sequencers based on manufacturer protocols. RNA sequence analysis was performed based on the pipeline analysis as described in Haas & Zody 2010 (Haas, Brian J., and Michael C. Zody. "Advancing RNA-seq analysis." Nature biotechnology 28.5 (2010): 421). The analysis of the RNA reads obtained via Illumina analysis were mapped to the Applicant's oil palm reference genome (data not published) to allow for correct assembly and quantification of transcripts reads. RNA for transcriptome sequencing was prepared based on protocols recommended by

Illumina TruSeq Sample Preparation Kit. The RNA sequencing (RNA-Seq) library was prepared using Illumina TruSeq RNA Sample Preparation Kit v2. Prior to generating a RNA-Seq library, RNA integrity was validated on Agilent 2100 Bioanalyzer (Agilent Technologies) using RNA Nano LabChip. Only RNA samples with RIN 8 and above were quality checked to proceed with the subsequent steps. 4 μg of total RNA was used and mRNA was purified using poly-T oligo-attached magnetic beads (AMPure XP Beads). After mRNA purification, the mRNA was fragmented and converted into cDNA using superscript II reverse transcriptase. Adapters were ligated to the cDNA fragments and the adaptor-cDNA fragments were then enriched by PCR for 12 cycles. The library was validated on Bioanalyzer High Sensitivity DNA Chip to ensure that the library fragments range from 250~500 bp, and then subjected to the HiSeq 2000 sequencer for sequencing. In one method, the analysis began with raw RNA-seq reads generated from the tissues extracted and concludes with visualisation of the analysis. All tools used in the protocol are publicly available (on the internet), actively maintained by a team of developers and adopt well-accepted data storage and transfer standards.

First, reads for each condition were mapped to the Applicant' s proprietary oil palm reference genome with TopHat. After running TopHat, the resulting alignment files were provided to Cufflinks to generate a transcriptome assembly for each condition. These assemblies were then merged together using the Cuffmerge utility, which is included with the Cufflinks package. This merged assembly provides a uniform basis for calculating gene and transcript expression in each condition. The reads and the merged assembly were fed to Cuffdiff, which calculates expression levels and tests the statistical significance of observed changes. Cuffdiff also performs an additional layer of differential analysis. Subsequently, Cuffdiff identifies genes that are differentially regulated at the transcriptional or post-transcriptional level. The results are reported as a set of text files and can be displayed in the plotting environment of the user's choice.

Visualisation of the transcript level of the genes were plotted using a R package plotting tool called CummeRbund (http://compbio.mit.edu/cummeRbund/), which provides functions for creating commonly used expression plots such as volcano, scatter and box plots. CummeRbund also handles the details of parsing Cufflinks output file formats to connect Cufflinks and the R statistical computing environment. CummeRbund transforms Cufflinks output files into R objects suitable for analysis with a wide variety of other packages available within the R environment and can also now be accessed through the Bioconductor.

The so-called MYB transcription factor is of special interest, as it is known in the art that some MYB variants are responsible for pigmentation variations in potato, apple, tomato and pepper. A total of 18 MYB genes were identified in the regions of interest.

Three of these 18 MYB genes were found in chromosome 8 of the Applicants' proprietary reference genome. These three MYB genes were of special interest as promising candidates for fruit colour variation in oil palm because variants in MYB transcription factors are known to cause variation in pod-colour pigmentation in cacao, grapes and other plant species. Based on the hypothesis that the mutation causing the virescens trait is a mutant of an MYB transcription factor, the MYB genes were examined to determine if their expression pattern in tissue of ripe and unripe fruits with the two different fruit colour types supports this hypothesis. It was found that the three MYB genes conform to the expected expression pattern. It was found that the expression of MYB transcription factor was significantly higher for the nigrescens unripe stage compared to the nigrescens ripe, virescens unripe and virescens ripe stages. Based on this, the three MYBs were identified, namely MYB001, MYB002 and MYB003. These three MYBs were hypothesized to be related to the phenotype that causes the oil palm fruit exocarp to be pigmented orange/green (virescens trait), instead of the dark purplish colour (nigrescens trait).

Phylogenetic analysis of the three MYB genes was performed, the results of which are shown in Figure 1. Phylogenetic analysis was used to determine the evolutionary relationships of the MYB genes. The sequences were retrieved from UniProt and NCBI GenBank and were compared with the three MYB genes. A phylogenetic tree was then drawn using the CLUSTALW program. From the phylogenetic analysis, it was observed that the three candidate MYB genes were part of the same gene cluster and were very likely involved in the anthocyanin pathway. Based on this, it was deduced that the three MYB genes play a role in regulating fruit exocarp colour, hence the region containing these MYB genes was studied further.

EXAMPLE 3: ELUCIDATION OF REGION OF INTEREST

In order to further study the three candidate MYB genes MYB001, MYB002 and MYB003, SeqCap EZ Developer sequencing libraries were prepared, by building upon an optimized design algorithm by Roche NimbleGen following manufacturer' s instructions. SeqCap EZ oligo probes were designed based on the Applicant' s proprietary oil palm reference genome, encompassing the regions flanking the MYB genes. The protocol of the target capture was based on Roche NimbleGen SeqCap EZ Library SR User's Guide Version 3.0 and was provided by the manufacturer (h(tp://www.nimblegenxx¾n^roducts lit/seqcap/). The library was used to capture the targeted regions that span the three MYB genes for 14 samples. Sequencing was then performed and mapping of each sample to the Applicant's proprietary oil palm reference genome was conducted.

The SeqCap EZ Developer Library targets a region of interest that span the three candidate MYB genes and all the genes involved in anthocyanin and carotenoid biosynthesis pathways. The region elucidated by SeqCap is Haplotype Block A

(9,688,515bp). Twelve samples of virescens, and two samples of nigrescens from Population A, plus a nigrescens dura palm from Population D, were used to perform this solution-based capture method using the SeqCap EZ Developer Library and sequenced on Illumina HiSeq2000. SNP markers found using this target enriched sequencing method were utilised as genetic markers and for further haplotype analysis. To ensure the genotype for the SNPs was determined accurately, nucleotide counts at each site for each individual were used in a maximum likelihood framework, as explained in Hohenlohe et al. (Hohenlohe, P. A., Bassham, S., Etter, P. D., Stiffler, N., Johnson, E. A., Cresko, W. A. (2010) Population Genomics of Parallel Adaptation in Threespine Stickleback using Sequenced RAD Tags. PLos Genetics, 6(2): el000862

(23pp)), to assign the diploid genotype.

EXAMPLE 4: MARKER BASED ANALYSIS Novel simple sequence repeats (SSRs) and insertion-and-deletion (INDEL) markers mined from ACGT' s oil palm genome data were used for data validation. A physical map was constructed according to the scaffold and optical map position of the genotyped markers. Marker accuracy was calculated based on the phenotypic and genotypic data gathered. An accuracy plot was then constructed and is shown in Figure 2. As can be seen in Figure 2, a region of 2.5Mbps shows a 100% SSR accuracy. An example is provided in Table 2 below to demonstrate how one of the SSR marker, SEQ ID NO: 12806 was able to distinguish the virescens and nigrescens fruit colours in Population A with 100% accuracy by matching the SSR expected allele sizes.

Table 2: Correlation of virescens (Vir) and nigrescens (Nig) palms with expected allele size for marker SEQ ID NO: 12806

Eight Population A samples were screened for a total of 236 SSRs and 74 INDELs, which were mined from the Applicant' s proprietary oil palm genome data and target capture data. Of these mined markers, 95 SSRs and 67 INDELs were polymorphic and were also selected for further genotyping. Overall, a total of 123 markers (63 Applicant' s SSRs and 60 INDELs) were scorable. In the present example, "scorable" refers to the genotyping results that provide information that fits a heritability model and clear results such that the alleles can be "binned" into AA, AB or BB genotypes. This would require the alleles to be polymorphic, be capable of providing clear separation (where gels are used), and the allelic segregation pattern to match the expected patterns of AA, AB or BB. "Non-scorable" results, on the other hand, would include for example, non-polymorphism, non-standard allelic segregation patterns, lack of information, inability to cluster and call alleles due to experimental or fluorescence issues.

The accuracies of the scorable markers were calculated and are shown in Tables 3 and 4 below. Out of the 123 scorable markers, 51 markers (20 Applicant' s SSRs and 31 INDELs) located in Haplotype Block A within the position of 3,208,714 to 5,742, 135 showed 100% accuracy. This region is referred to as Haplotype Block C.

The Applicant' s proprietary oil palm reference genome (data not published) and the information found in Tables 3 and 4 was used to perform data analysis of the genotype call versus the ability to predict the trait of interest. By analysing linkage disequilibrium (LD) between the individual plants, the fact that the region is a haplotype block is inferred based on the high correlation between the ability of the allele to predict the vir trait and the actual vir trait exhibited by the plant. A random unlinked allele will only have 50% chance to be linked to a neighbouring allele in the case where there is no LD and the allele distribution is natural, therefore having multiple markers linked together to each other without random segregation being exhibited shows that a region is in LD and therefore the entire region is a haplotype block that is linked to the trait it exhibits. The 2.5Mbps region, termed Haplotype Block C (SEQ ID NO: 13297) had markers which were genotyped within this region which are able to predict the vir trait with at least 96%, 97%, 98%, 99% and 100% accuracy.

Based on the data obtained from sequencing and genotyping of the MYB genes, the haplotypes were identified for positions that code for the three MYB genes (MYB001 , SEQ ID NO: 12891 ; MYB002, SEQ ID NO: 12892; and MYB003, SEQ ID NO: 12893). The haplotypes associated with the three MYB genes appear to cluster with the haplotype associated with the phenotype of the sequenced sample. These results indicate that there is association between the three MYB transcription factors and pod- colour variation across multiple samples with the same genetic background. This finding further reinforces that the MYB genes located in this region of the haplotype block sequence are responsible for regulating the anthocyanin pathway.

The INDELs and their positions within Haplotype Block A (SEQ ID NO: 13020 to 13294, or SEQ ID NO: 13295) are shown in Table 3, while the SSRs, their positions within Haplotype Block A (SEQ ID NO: 13020 to 13294, or SEQ ID NO: 13295) and their respective forward and reverse primers are shown in Table 4. The SNPs and their positions within Haplotype Block A (SEQ ID NO: 13020 to 13294, or SEQ ID NO: 13295) are shown in Table 10. The term "estimated predicted success" in Tables 3, 4 and 10 denotes the ability of a marker to correctly predict the presence of the virescens gene trait in oil palm plants in all populations tested. Table 3: Determined INDELs and their positions within Haplotype Block A (SEQ

ID NO: 13295). The term "estimated predicted success" denotes the ability of an INDEL to correctly predict the presence of the virescens gene trait.

GC ACCT

CTATCCGTACTTGGCTTC GTATTGCTAAGCGACT

3509571 */-CT 12856 12985 100

AC GGAG

TGCGGTATAAGAAATCA ATCCAATTTAGCTGTG

3749887 */-CATG 12857 12986 100

GGT CATT

AAGGCTGCAGACATAAC ATGCTACCTAACAGAC

3807519 */+T 12858 12987 100

AGT GCAT

CAAAGGAAGGAAACATT GACCCACCAAATTTAT

3967194 */-TT 12859 12988 100

TTG TGAA

AGCCATACAAAAACAGA TCAGCATGCATCTTAT

3997563 */+AT 12860 12989 100

ATGA TTCA

CCGTATCAAACCAATGA TCGTCCTTGGTTACCA

4065522 */-TT 12861 12990 100

AAT TATC

TTTATTTTTGGATTTGGG TTTTCACACCTATTTC

4073269 */-ATA 12862 12991 100

TG CTGG

*/- GAGTG TAGATTTTGTTGGGGATC GGTATCATATCGCCAT

4129771 12863 12992 100

AAGGG TG GTTT AGGA

*/+CTC AGGGGCTGTCTAATAGGT AGTCCAATTATGTCAC

4591275 12864 12993 100

TC TC CAGG

CTGAACTGTGTCCAAGGA AATTAGATTGCCTTTT

4612628 */-TTTG 12865 12994 100

TT TCCC

GAACCTTGATTGGCTAAG TGTTGTGACAAAGGAT

4665980 */-A 12866 12995 100

TG TGAA

ATTGTCCATGTCCATACC GCATCTTCGAGACATA

4675852 */-T 12867 12996 100

AT AAGG

TAATTCTCTCTCACCCCA AGAGAAGTGGACGGT

4677862 */+T 12868 12997 100

AA TGATA

TCCTTTGTCATCTACCCA AATTTTGGAACTACCC

4740946 */+C 12869 12998 100

TC TTCC

TCACGCATTATCCCTTTA TGTTCCACGTTACAAG

4749206 */-A 12870 12999 98.78

CT ATGA

TCATCTTGTAACGTGGAA ATGAACCATCTATCCT

4749316 */-G 12871 13000 98.78

CA GCAC

GCCGAACTGATAGAGAA GAATCCTTTACCTGAG

4751212 */+T 12872 13001 100

ATG CAGA

ATACGTATCTTCTTCGTC TAAAAATGAATCATG

4763793 */-A 12873 13002 100

CG CCCTT

TGTAGGCTCCTTGGATAC GGGCACAAACACAAG

4816599 */-A 12874 13003 100

AG TTATT

AGTCATTACATGGAAGCC TAAAAAGACGTAAGG

4861815 */+T 12875 13004 100

AG GGTGA

GCCAATTCAATGATCAGA TGGCTTTGAAATCAAT

4871285 */+T 12876 13005 100

TT TTTT

GCACCCACTCGTACATCT TAGGCAAAGAGCAAA

4928989 */-TC 12877 13006 100

AT GTAGG

GAGAGAGAGGAAGTGGG TCATCTTGTCCTTACC

5112316 */+GG 12878 13007 100

AGT AACC

GTTGATCGATGGTTGAGA CTGCTAAAATTACGAG

5168119 */-AA 12879 13008 100

CT CGAT

AGGTGGAGAGAAAGCAC GGGATAAAATTGGGG

5196847 */+TA 12880 13009 100

ATA ATAGA

AGAGTTATGATAATGAG CCTTTTTACAGCGGTA

5208823 */+TA 12881 13010 98.78

CGGTT CATC

CCTCCTTTTCTCTTAGCCT ACTACGACCACACCAT

5243695 */-GG 12882 13011 100

C CTTC

ATATCTTGATTTGCCACC TCCAAATCAGTCAATA

5293577 */+A 12883 13012 100

AC AGCA AAGCACGACGTTGAAAC TGTTGCAATGACAATT

5372803 */-A 12884 13013 100

TAT CTGT

TCCTATGTTTCTTCTGCG CTATTTGGGCAACATT

5417000 */+A 12885 13014 100

AT TAGG

TCAATTCAGGAGCAGAA TTGAATGGAGACTAA

5486619 */-A 12886 13015 100

AGT GCCAT

GGTCAATATTCAGAAGTC GCTCAAGGGTCTACAC

5660732 */+A 12887 13016 98.78

CG TCAG

*/- CATTATAAGTGCCGAGG ACATGCAAAACTTTCA

5742135 12888 13017 100

GAAG AAA CCTT

GGGATTCCTCTTATGCTT CGGAATCTACCGTACA

5952347 */-C 12889 13018 98.78

TT TAGG

AGCGAGAAGGTGTGTAA

6165498 */-A 12890 GCATAGTCATTGGGAAATGT 13019 98.78

AGA

Table 4: Determined SSRs and their positions within Haplotype Block A (SEQ ID NO: 13295). The term "estimated predicted success" denotes the ability of an SSR to correctly predict the presence of the virescens gene trait. These SSR Markers 5 were tested on multiple locations throughout the contiguous region to determine their

accuracy in predicting mutation that controls fruit exocarp colour.

ATGACACATCGTTGG GGATTGTCAT

2778572 2778583 (TC)6 12782 12911 98.78

ATTCT AATAGGGGGT

CAAAATACCCATCG GAGGAGGAGA

3032892 3032917 (CT)13 12783 12912 98.78

AATGAT GAAGGGTTTA

GTGCTTCCTGTACTA CCGGTCATTCT

3076382 3076393 (TA)6 12784 12913 98.78

AACCG CATAGTGAT

AGCCATTGAGCACTC TCGATATGCCC

3208714 3208747 (TG)17 12785 12914 100

TACAT TAATATGCT

ATGGTTGCTTGATTT ATTCATTGGCA

3401362 3401375 (AT)7 12786 12915 100

TGAGT TAAGGAAAA

CCTGAAGCTCCTTCT AGTCTTGATCC

3530980 3530991 (CT)6 12787 12916 100

TTTCT AATGGTTTG

TCAGGCCTAAAATTT AGGTTTTGGCT

3578841 3578924 (TA)42 12788 12917 100

CAAAG TAATTGGAT

TGACTTTCTGT

AACGATATTAGATG

3810373 3810384 (AT)6 12789 12918 AGAGGGTATC 97.56

ATGTGGA A

GTGGTTATAGCCAA TAAACCATTC

3977391 3977416 (TC)13 12790 12918 100

GAGACG GAAACAGAGG

CAATAATGGGCTAA CCCCAGATGTT

4007288 4007299 (TG)6 12791 12920 100

AAATCAA AGGATATGA

GATGTATCCCCTCAA CTTTGGTACAC

4130882 4130911 (AG) 15 12792 12921 100

CAGAA AGACAGGGT

ACGAGTCTCCCTTTA CTTCTCACGTT

4199184 4199245 (TA)31 12793 12922 100

AAACC AAGCCACTC

GTCGAAACTCAACA CCAACATCATT

4417217 4417234 (TA)9 12794 12923 100

GCTAGG CGAGGTATT

CAAGGAAGGAGTTG GCTTCTAGAA

4486176 4486199 (TQ12 12795 12924 100

TGAGAG AGCAAGGACA

CATGCATCACTTGAC TCCTATGCCCT

4650922 4650937 (TA)8 12796 12925 100

AAGAC CTCAATCTA

AGTAGGAGTCAGGG AATTTTGACTG

4689967 4689993 (ATA)9 12797 12926 100

CGTG ACATATTTGAT

GAGTAATACCCGAC ATGGAGTCTT

4790122 4790137 (AT)8 12798 12927 84.15

CCATTT AAGGGAGGAG

AACCAAAGAT

CAACTTTCTTGATTT

4792950 4792964 (AAT)5 12799 12928 TTTACCAAGAT 100

CGATGT G

CTTGTACCGAAAAG CTTAACGTCTC

4814881 4814895 (GGA)5 12800 12929 100

CAGACT CCTCTCCTT

CCTCACAACTAGTCG GTTTTTCCATC

4864510 4864560 (ATA) 17 12801 12930 100

GTCAT AAATCAGGA

TATTGAGCACGAGT CTTAATTCGAG

4897237 4897248 (AT)6 12802 12931 98.73

AGCTTG ATCAACCGA

TATAGCCTTTTTCCC ACGTTCGGAT

4934204 4934215 (AT)6 12803 12932 100

ACTTG ATGCTAAAAA

ACGAATAAATTGGA GCACGATTAC

4948701 4948716 (CT)8 12804 12933 100

GGGTTT AAAAGGTAGG

CAGATGAAACTCAC ATCTCTCCCCT

4993417 4993436 (TA)10 12805 12934 100

CTGGAT TTCAAAAAC

5053912 5053963 (AT)26 12806 CATTGCAGCTTTAGA 12935 AATCACCGCA 100 CAATG CAAGTAGAGT

TGGAAGTAACTCAT GGATGATGCT

5613463 5613478 (CA)8 12807 12936 100

GTTGGA GCAAT AATTT

AGATTAGATCGCAA ATGACTTGGA

5640684 5640713 (GA)15 12808 12937 98.78

ATTCCA GCTGAAAAGA

TTCGTTTTGCAGGTA CATCGATGTA

5786993 5787054 (TA)31 12809 12938 98.78

TTCTT GAACTCCCAT

GTCCTTATTTCCTGG AACTTTCTAGC

6093805 6093816 (CA)6 12810 12939 98.78

CTTTT AGCATCTCG

AGTGGATGATGCTAT GCAGAAAAGG

6280757 6280768 (AT)6 12811 12940 97.56

CAAGG AACGTTAAAA

AGCCAAGCAAATCT TAATGTGGGT

6419987 6420014 (TG)14 12812 12941 97.56

TAAACA CTTTCTGCTC

TGAGGAAGAA

ACATAATGGAGTTA

6470963 6471036 (AT)37 12813 12942 GAAATAGAAT 97.56

CTGGCAA CA

GATAGTCGGTTCGTA TGACGCAACT

6618994 6619017 (AT) 12 12814 12943 97.56

AGCTC CAAATATCAA

ATGCTTTTTCTCTTTT CCGACATATCT

6693429 6693448 (CCGA)5 12815 12944 98.78

CCCT TCAGTCGAT

TATCCACCATTCTCT TAAATTGTGG

6794078 6794103 (AG) 13 12816 12945 97.56

TTGCT AGGAGGAATG

GTTCTTCACCCGTAG AACCAGATCT

6869878 6869947 (AT)35 12817 12946 96.34

CATAG GAGTCCAAAA

CCTCTCATATTACCC TGGTTAGCTTG

6945342 6945365 (AG) 12 12818 12947 96.34

ACCAA GAACTGTCT

CTTTGGTTTTGGAAG TATCCATTAAC

6955509 6955534 (TA)13 12819 12948 96.34

AGCTA AAGGCTGCT

TTCCATACCATCTTG TGTCTCCATCC

7046963 7046978 (AG)8 12820 12949 96.34

ATTCC CTGTTTTAC

ATATGTCTCCGTAAT TGTTGGTGTTG

7245122 7245149 (AG) 14 12821 12950 95.12

GGCTG GACTTAACA

GGGTCTTAGCCCACT CAATTGGTAA

7500109 7500130 (CA)l l 12822 12951 93.9

AATTT TTCCGATCAT

TCTAATGAGAGATCC ACAGACCTCT

7584023 7584034 (GA)6 12823 12952 93.9

TCCGA CCCCTAAAAG

ACCTCACCAACTTCA CTCCCCTCTGT

7790206 7790221 (GA)8 12824 12953 91.46

TTGAG CTCTCTCTT

CTTCATTCTTCTTCCT AGGGAGATTG

8171077 8171094 (GCG)6 12825 12954 90.24

CGAC AGATCCAGA

TCAACTCGGACTGG AACTCACAAG

8277544 8277557 (TC)7 12826 12955 90.24

ACTTAC CTGCCATTAT

TGTCATTTCTCCCTC ATGCATGTGG

8369867 8369908 (TTA)14 12827 12956 90.24

ATTTC TGCAATAATA

TAACTAGTCGAAGA TGCTTGCAATG

9218814 9218837 (TA)12 12828 12957 90.24

CCCGTG CTCTTATTA

ACCATATAAATAGG GGGATAAGGG

9419650 9419665 (TA)8 12829 12958 90.24

GCGGAT ATTAGGAAAA

TCTCTTCTTTGACAT TGGATAGCAA

9688504 9688515 (AG)6 12830 12959 89.02

TGCCT TGAACCTTTT EXAMPLE 5: RE-SEQUENCING OF THREE MYB GENES

Sequence validation was performed using the Sanger sequencing method. Sequencing primers were designed to amplify the three MYB genes and sequenced using the Sanger sequencing platform Applied Biosystems 3730x1 sequencers using manufacturer recommended protocols. This was also performed to identify lesions in the three MYB genes, which may potentially cause a disruption of colour development when expressed. Nested primers were designed and using a total of 28 primer sets, the three complete MYB genes, as well as the flanking regions, were amplified.

Table 5: Sequencing primers used for the amplification and sequencing of the three

MYB genes

ATGCT CA

Primer_ID_NO:21 13338 TAGGAGAGGGGTGCCAACC 13339 TCTTCTCATCCCAGCACAGC

A C

Primer_ID_NO:22 13340 CCGACAAACCTCAGATGACT 13341 TGGTCCTCTGTTTGAATTTA

TGA ACTCT

Primer_ID_NO:23 13342 TGGGAAGGAGTGTGGGGAA 13343 AAGCGATCGGTGCTTTGCT

A T

Primer_ID_NO:24 13344 GGCGGGATCTCATAACTATT 13345 TGCATTCATGTCTGTGTAAA

TG GTGG

Primer_ID_NO:25 13346 TCAGCGAAAATCCATAGCAC 13347 TGCAAACCGGTGTTCCTTTT

TCC C

Primer_ID_NO:26 13348 CGCCCACAAACCTATCTCCA 13349 TGGTGCCATTTCCATTTTCC

A

Primer_ID_NO:27 13350 AATGATGTGGGGGTTCGTGG 13351 TGTTGAAAGCTATGTTTTGT

CACTT

Primer_ID_NO:28 13352 GGAAGTCCAAGGAGAGAGG 13353 TGA AT AG AT A ACT ATCC G A

CA TCCGT

In total, 256 samples were sequenced using the Sanger sequencing method. Oil palms of three different populations were chosen to test the accuracy of the markers in predicting the trait. The three populations of oil palm used were Nigerian Tenera X Nigerian Tenera (selfing) (Population A), Nigerian Dura X AVROS Pisifera (Population B) and Angola Tenera X Angola Tenera (selfing) (Population C), and were analysed for the virescens (Vir) trait.

Based on the analysis of the SNPs identified, the allele combination that determines if the trait carried is a virescens or nigrescens was determined. The trait is inherited through a dominant bi-allelic mode. Therefore, vir/vir combination gives rise to nigrescens plants, whereas the Vir/Vir and Vir/vir alleles give rise to the virescens trait in oil palm. This model is in line with observations on the segregation of the trait and also correlates with the marker profiles ascertained through testing. Any markers that do not adhere to this model were discarded.

From the Sanger sequencing results, 36 potential SNPs (one potential SNP for MYB001, 17 SNPs for MYB002 and 16 SNPs for MYB003) were identified that were able to distinguish the Nigrescens oil palms from the Virescens oil palms. Twelve SNPs for MYB002 are within the MYB002 gene. One SNP (SEQ ID NO: 4901) was found to work across all three oil palm populations, with this particular SNP shown to result in a non- synonymous change in the corresponding amino acid (resulting from the mutated nucleic acid codon), thus resulting in a change in the protein composition. The SNPS referred to above are listed in Tables 6 to 10 below. All the SNPs denoted by an asterisk (*) are able to differentiate between Nigrescens and Virescens. For example, Position 4758820* (SEQ ID NO: 4898) means this SNP can differentiate between Nigrescens and Virescens in Population A, Nigerian Tenera X Nigerian Tenera (selfing). One SNP Position 4759393* (BINGO) (SEQ ID NO: 4901), can differentiate between Nigrescens and Virescens across all three Populations A, B and C tested. SNP positions in italics in Tables 6 to 8 are those that are present within the gene region, while those not in italics are those that are present outside the gene but are located near the gene. These are also summarized in Tables 9(a), 9(b) and 9(c).

Table 6: SNPs found in the gene MYB001

Table 7: SNPs found in the gene MYB002

Table 7 (continued)

Table 8: SNPs found in the gene MYB003

5 Table 8 (continued)

Table 9. SNPs in MYBOOl, MYB002 and MYB003 that are present within the gene region and outside (but nearby) the gene

(a) MYBOOl (b) MYB002

SNP in gene

SEQ_ID_NO:ll

(c) MYB003

Table 10. List of all SNPs found in the Haplotype block A region (SEQ ID

SEQ ID NO: 87 1105654 100.00 SEQ ID NO 135 1595447 100.00

SEQ ID NO:88 1136987 90.91 SEQ ID NO 136 1595548 84.62

SEQ ID NO: 89 1160626 100.00 SEQ ID NO 137 1595552 100.00

SEQ ID NO:90 1184499 100.00 SEQ ID NO 138 1595612 100.00

SEQ ID NO:91 1184532 100.00 SEQ ID NO 139 1595634 100.00

SEQ ID NO:92 1184992 92.31 SEQ ID NO 140 1598971 75.00

SEQ ID NO:93 1186507 100.00 SEQ ID NO 141 1598986 75.00

SEQ ID NO:94 1196945 85.71 SEQ ID NO 142 1599060 100.00

SEQ ID NO:95 1198753 85.71 SEQ ID NO 143 1599064 100.00

SEQ ID NO:96 1198767 91.67 SEQ ID NO 144 1599093 75.00

SEQ ID NO:97 1199162 100.00 SEQ ID NO 145 1599194 100.00

SEQ ID NO:98 1227506 80.00 SEQ ID NO 146 1599228 100.00

SEQ ID NO:99 1228225 91.67 SEQ ID NO 147 1607142 83.33

SEQ ID NO: 100 1229099 87.50 SEQ ID NO 148 1609239 100.00

SEQ ID NO: 101 1229694 80.00 SEQ ID NO 149 1610161 100.00

SEQ ID NO: 102 1229712 92.86 SEQ ID NO 150 1610278 100.00

SEQ ID NO: 103 1229729 100.00 SEQ ID NO 151 1610840 84.62

SEQ ID NO: 104 1235653 83.33 SEQ ID NO 152 1611080 100.00

SEQ ID NO: 105 1257584 100.00 SEQ ID NO 153 1611809 100.00

SEQ ID NO: 106 1264007 100.00 SEQ ID NO 154 1612038 100.00

SEQ ID NO: 107 1276582 75.00 SEQ ID NO 155 1612044 100.00

SEQ ID NO: 108 1281872 100.00 SEQ ID NO 156 1612184 100.00

SEQ ID NO: 109 1281883 100.00 SEQ ID NO 157 1612381 100.00

SEQ ID NO: 110 1325791 100.00 SEQ ID NO 158 1612617 85.71

SEQ ID NO: l l l 1377950 91.67 SEQ ID NO 159 1619056 80.00

SEQ ID NO: 112 1384041 100.00 SEQ ID NO 160 1619101 100.00

SEQ ID NO: 113 1591964 100.00 SEQ ID NO 161 1619123 75.00

SEQ ID NO: 114 1592006 100.00 SEQ ID NO 162 1619488 100.00

SEQ ID NO: 115 1592495 100.00 SEQ ID NO 163 1619550 100.00

SEQ ID NO: 116 1592560 100.00 SEQ ID NO 164 1620384 100.00

SEQ ID NO: 117 1592823 100.00 SEQ ID NO 165 1620516 100.00

SEQ ID NO: 118 1592833 92.31 SEQ ID NO 166 1621441 100.00

SEQ ID NO: 119 1593004 100.00 SEQ ID NO 167 1621451 100.00

SEQ ID NO: 120 1593011 100.00 SEQ ID NO 168 1621520 100.00

SEQ ID NO: 121 1593020 92.86 SEQ ID NO 169 1621631 100.00

SEQ ID NO: 122 1593034 100.00 SEQ ID NO 170 1621697 75.00

SEQ ID NO: 123 1593275 100.00 SEQ ID NO 171 1623231 100.00

SEQ ID NO: 124 1593287 85.71 SEQ ID NO 172 1623516 75.00

SEQ ID NO: 125 1593362 100.00 SEQ ID NO 173 1623667 100.00

SEQ ID NO: 126 1594500 100.00 SEQ ID NO 174 1623927 92.31

SEQ ID NO: 127 1594853 100.00 SEQ ID NO 175 1624146 100.00

SEQ ID NO: 128 1594892 100.00 SEQ ID NO 176 1624249 100.00

SEQ ID NO: 129 1595191 100.00 SEQ ID NO 177 1624275 100.00

SEQ ID NO: 130 1595265 100.00 SEQ ID NO 178 1624294 100.00

SEQ ID NO: 131 1595309 100.00 SEQ ID NO 179 1624622 100.00

SEQ ID NO: 132 1595322 100.00 SEQ ID NO 180 1624791 92.86

SEQ ID NO: 133 1595411 100.00 SEQ ID NO 181 1625995 100.00

SEQ ID NO: 134 1595433 100.00 SEQ ID NO 182 1626388 84.62 SEQ ID NO: 183 1626746 86.67 SEQ ID NO:231 1653217 90.91

SEQ ID NO: 184 1626816 100.00 SEQ ID NO:232 1653227 91.67

SEQ ID NO: 185 1627140 100.00 SEQ ID NO:233 1653258 100.00

SEQ ID NO: 186 1627246 100.00 SEQ ID NO:234 1653370 100.00

SEQ ID NO: 187 1627594 100.00 SEQ ID NO:235 1656056 100.00

SEQ ID NO: 188 1627653 100.00 SEQ ID NO:236 1656097 83.33

SEQ ID NO: 189 1628003 100.00 SEQ ID NO:237 1656162 100.00

SEQ ID NO: 190 1628045 100.00 SEQ ID NO:238 1656251 100.00

SEQ ID NO: 191 1628088 93.33 SEQ ID NO:239 1656278 100.00

SEQ ID NO: 192 1628371 100.00 SEQ ID NO:240 1656286 90.91

SEQ ID NO: 193 1629267 100.00 SEQ ID NO:241 1656329 100.00

SEQ ID NO: 194 1629424 100.00 SEQ ID NO:242 1656391 100.00

SEQ ID NO: 195 1629574 100.00 SEQ ID NO:243 1656493 83.33

SEQ ID NO: 196 1629796 100.00 SEQ ID NO:244 1656503 100.00

SEQ ID NO: 197 1630574 100.00 SEQ ID NO:245 1656537 100.00

SEQ ID NO: 198 1644111 75.00 SEQ ID NO:246 1656864 100.00

SEQ ID NO: 199 1644178 100.00 SEQ ID NO:247 1656928 75.00

SEQ ID NO:200 1644186 100.00 SEQ ID NO:248 1656977 100.00

SEQ ID NO:201 1644306 100.00 SEQ ID NO:249 1657008 100.00

SEQ ID NO:202 1645661 100.00 SEQ ID NO:250 1657091 100.00

SEQ ID NO:203 1645922 100.00 SEQ ID NO:251 1657209 87.50

SEQ ID NO:204 1646268 100.00 SEQ ID NO:252 1657268 100.00

SEQ ID NO:205 1646564 100.00 SEQ ID NO:253 1657299 91.67

SEQ ID NO:206 1646675 80.00 SEQ ID NO:254 1657385 83.33

SEQ ID NO:207 1646868 100.00 SEQ ID NO:255 1657460 88.89

SEQ ID NO:208 1646900 100.00 SEQ ID NO:256 1657606 88.89

SEQ ID NO:209 1647115 100.00 SEQ ID NO:257 1657741 87.50

SEQ ID NO:210 1647649 91.67 SEQ ID NO:258 1657940 100.00

SEQ ID NO:211 1650082 100.00 SEQ ID NO:259 1657968 100.00

SEQ ID NO:212 1651202 100.00 SEQ ID NO:260 1657993 100.00

SEQ ID NO:213 1651272 85.71 SEQ ID NO:261 1658230 83.33

SEQ ID NO:214 1651941 92.31 SEQ ID NO:262 1658296 100.00

SEQ ID NO:215 1652378 100.00 SEQ ID NO:263 1658359 100.00

SEQ ID NO:216 1652440 92.86 SEQ ID NO:264 1658457 100.00

SEQ ID NO:217 1652487 100.00 SEQ ID NO:265 1658541 80.00

SEQ ID NO:218 1652530 92.86 SEQ ID NO:266 1658695 100.00

SEQ ID NO:219 1652552 92.86 SEQ ID NO:267 1658950 100.00

SEQ ID NO:220 1652652 92.86 SEQ ID NO:268 1659279 100.00

SEQ ID NO:221 1652830 100.00 SEQ ID NO:269 1659285 100.00

SEQ ID NO:222 1652858 80.00 SEQ ID NO:270 1659387 100.00

SEQ ID NO:223 1652908 92.86 SEQ ID NO:271 1659444 100.00

SEQ ID NO:224 1653008 92.86 SEQ ID NO:272 1659490 100.00

SEQ ID NO:225 1653077 92.86 SEQ ID NO:273 1659500 80.00

SEQ ID NO:226 1653107 100.00 SEQ ID NO:274 1659654 100.00

SEQ ID NO:227 1653132 92.86 SEQ ID NO:275 1659811 100.00

SEQ ID NO:228 1653175 92.31 SEQ ID NO:276 1660076 80.00

SEQ ID NO:229 1653181 91.67 SEQ ID NO:277 1660082 100.00

SEQ ID NO:230 1653209 100.00 SEQ ID NO:278 1660115 85.71 SEQ ID NO:279 1660138 100.00 SEQ ID NO:327 1665597 100.00

SEQ ID NO:280 1660192 100.00 SEQ ID NO:328 1665632 100.00

SEQ ID NO:281 1660270 100.00 SEQ ID NO:329 1666256 100.00

SEQ ID NO:282 1660315 100.00 SEQ ID NO:330 1666300 100.00

SEQ ID NO:283 1660529 100.00 SEQ ID NO:331 1666331 84.62

SEQ ID NO:284 1660563 75.00 SEQ ID NO:332 1666383 100.00

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SEQ ID NO: 897 1986592 100.00 SEQ ID NO:945 2030164 75.00

SEQ ID NO: 898 1986720 100.00 SEQ ID NO:946 2033044 92.31

SEQ ID NO: 899 1986951 100.00 SEQ ID NO:947 2034032 100.00

SEQ ID NO:900 1987559 100.00 SEQ ID NO:948 2035544 100.00

SEQ ID NO:901 1989195 100.00 SEQ ID NO:949 2035582 100.00

SEQ ID NO:902 1990125 91.67 SEQ ID NO:950 2036176 100.00 SEQ ID NO:951 2036925 100.00 SEQ ID NO 999 2088984 100.00

SEQ ID NO:952 2037140 100.00 SEQ ID NO 1000 2089237 92.86

SEQ ID NO:953 2037927 100.00 SEQ ID NO 1001 2090087 92.31

SEQ ID NO:954 2040335 100.00 SEQ ID NO 1002 2093278 100.00

SEQ ID NO:955 2040448 92.31 SEQ ID NO 1003 2095313 75.00

SEQ ID NO:956 2040841 100.00 SEQ ID NO 1004 2108924 100.00

SEQ ID NO:957 2041308 90.00 SEQ ID NO 1005 2109034 100.00

SEQ ID NO:958 2041958 100.00 SEQ ID NO 1006 2109977 100.00

SEQ ID NO:959 2041963 75.00 SEQ ID NO 1007 2122730 100.00

SEQ ID NO:960 2042004 80.00 SEQ ID NO 1008 2124523 100.00

SEQ ID NO:961 2042061 85.71 SEQ ID NO 1009 2124980 75.00

SEQ ID NO:962 2060946 87.50 SEQ ID NO 1010 2126800 100.00

SEQ ID NO:963 2060960 80.00 SEQ ID NO 1011 2129268 100.00

SEQ ID NO:964 2062409 80.00 SEQ ID NO 1012 2129291 100.00

SEQ ID NO:965 2062870 85.71 SEQ ID NO 1013 2129736 100.00

SEQ ID NO:966 2066854 75.00 SEQ ID NO 1014 2129906 100.00

SEQ ID NO:967 2067049 87.50 SEQ ID NO 1015 2130074 100.00

SEQ ID NO:968 2067206 87.50 SEQ ID NO 1016 2130671 100.00

SEQ ID NO:969 2067254 83.33 SEQ ID NO 1017 2130997 100.00

SEQ ID NO:970 2067307 92.31 SEQ ID NO 1018 2131011 100.00

SEQ ID NO:971 2067862 88.89 SEQ ID NO 1019 2131557 83.33

SEQ ID NO:972 2069393 87.50 SEQ ID NO 1020 2131606 84.62

SEQ ID NO:973 2069423 88.89 SEQ ID NO 1021 2131671 83.33

SEQ ID NO:974 2069488 90.00 SEQ ID NO 1022 2132514 100.00

SEQ ID NO:975 2069534 85.71 SEQ ID NO 1023 2132674 100.00

SEQ ID NO:976 2069545 100.00 SEQ ID NO 1024 2132987 100.00

SEQ ID NO:977 2069561 87.50 SEQ ID NO 1025 2133285 100.00

SEQ ID NO:978 2069568 85.71 SEQ ID NO 1026 2133398 100.00

SEQ ID NO:979 2069703 90.91 SEQ ID NO 1027 2133497 100.00

SEQ ID NO:980 2069713 90.91 SEQ ID NO 1028 2133885 100.00

SEQ ID NO:981 2069726 92.86 SEQ ID NO 1029 2134232 100.00

SEQ ID NO:982 2071215 100.00 SEQ ID NO 1030 2134889 100.00

SEQ ID NO:983 2071216 100.00 SEQ ID NO 1031 2134893 100.00

SEQ ID NO:984 2075509 100.00 SEQ ID NO 1032 2135230 100.00

SEQ ID NO:985 2079445 100.00 SEQ ID NO 1033 2135344 100.00

SEQ ID NO:986 2083356 100.00 SEQ ID NO 1034 2138235 100.00

SEQ ID NO:987 2083417 100.00 SEQ ID NO 1035 2141944 92.86

SEQ ID NO:988 2083458 100.00 SEQ ID NO 1036 2144551 92.31

SEQ ID NO:989 2083524 100.00 SEQ ID NO 1037 2145346 100.00

SEQ ID NO:990 2083813 92.31 SEQ ID NO 1038 2148907 100.00

SEQ ID NO:991 2083896 88.89 SEQ ID NO 1039 2148961 100.00

SEQ ID NO:992 2083991 87.50 SEQ ID NO 1040 2149779 100.00

SEQ ID NO:993 2086525 100.00 SEQ ID NO 1041 2155722 100.00

SEQ ID NO:994 2086593 100.00 SEQ ID NO 1042 2158887 92.86

SEQ ID NO:995 2087075 92.31 SEQ ID NO 1043 2166182 90.91

SEQ ID NO:996 2087247 92.86 SEQ ID NO 1044 2173104 83.33

SEQ ID NO:997 2087423 92.31 SEQ ID NO 1045 2173231 91.67

SEQ ID NO:998 2087562 100.00 SEQ ID NO 1046 2173267 100.00 SEQ ID NO 1047 2174468 100.00 SEQ ID NO 1095 2305194 92.86

SEQ ID NO 1048 2177946 90.91 SEQ ID NO 1096 2305231 92.31

SEQ ID NO 1049 2191179 100.00 SEQ ID NO 1097 2305632 80.00

SEQ ID NO 1050 2205849 92.86 SEQ ID NO 1098 2308379 90.00

SEQ ID NO 1051 2206080 100.00 SEQ ID NO 1099 2308762 91.67

SEQ ID NO 1052 2221173 83.33 SEQ ID NO 1100 2309335 92.86

SEQ ID NO 1053 2222281 85.71 SEQ ID NO 1101 2309364 88.89

SEQ ID NO 1054 2223221 71.43 SEQ ID NO 1102 2310323 100.00

SEQ ID NO 1055 2225061 100.00 SEQ ID NO 1103 2310566 92.86

SEQ ID NO 1056 2225302 100.00 SEQ ID NO 1104 2310635 90.91

SEQ ID NO 1057 2226894 100.00 SEQ ID NO 1105 2310734 92.31

SEQ ID NO 1058 2227286 100.00 SEQ ID NO 1106 2310855 100.00

SEQ ID NO 1059 2227352 87.50 SEQ ID NO 1107 2310902 100.00

SEQ ID NO 1060 2227794 100.00 SEQ ID NO 1108 2311253 90.91

SEQ ID NO 1061 2228425 100.00 SEQ ID NO 1109 2311265 92.31

SEQ ID NO 1062 2228487 100.00 SEQ ID NO 1110 2311418 92.86

SEQ ID NO 1063 2231099 100.00 SEQ ID NO 1111 2311469 92.86

SEQ ID NO 1064 2231474 80.00 SEQ ID NO 1112 2311500 92.31

SEQ ID NO 1065 2231927 85.71 SEQ ID NO 1113 2311551 92.31

SEQ ID NO 1066 2232057 90.91 SEQ ID NO 1114 2311571 92.31

SEQ ID NO 1067 2232134 100.00 SEQ ID NO 1115 2311606 92.86

SEQ ID NO 1068 2232175 84.62 SEQ ID NO 1116 2311635 92.31

SEQ ID NO 1069 2234788 90.00 SEQ ID NO 1117 2311647 92.86

SEQ ID NO 1070 2236637 86.67 SEQ ID NO 1118 2312558 100.00

SEQ ID NO 1071 2240917 86.67 SEQ ID NO 1119 2312590 100.00

SEQ ID NO 1072 2243659 92.86 SEQ ID NO 1120 2312632 100.00

SEQ ID NO 1073 2243703 100.00 SEQ ID NO 1121 2319698 100.00

SEQ ID NO 1074 2244413 75.00 SEQ ID NO 1122 2325204 92.86

SEQ ID NO 1075 2251595 92.86 SEQ ID NO 1123 2325218 92.86

SEQ ID NO 1076 2255254 92.86 SEQ ID NO 1124 2325269 92.86

SEQ ID NO 1077 2256491 92.86 SEQ ID NO 1125 2325299 80.00

SEQ ID NO 1078 2256808 92.86 SEQ ID NO 1126 2325349 75.00

SEQ ID NO 1079 2257193 92.86 SEQ ID NO 1127 2325750 92.86

SEQ ID NO 1080 2265314 100.00 SEQ ID NO 1128 2325758 100.00

SEQ ID NO 1081 2266862 100.00 SEQ ID NO 1129 2325768 100.00

SEQ ID NO 1082 2276631 92.86 SEQ ID NO 1130 2325824 92.86

SEQ ID NO 1083 2281969 75.00 SEQ ID NO 1131 2325922 100.00

SEQ ID NO 1084 2283186 90.00 SEQ ID NO 1132 2330938 91.67

SEQ ID NO 1085 2291192 93.33 SEQ ID NO 1133 2331263 90.91

SEQ ID NO 1086 2293288 83.33 SEQ ID NO 1134 2331272 90.91

SEQ ID NO 1087 2293705 80.00 SEQ ID NO 1135 2331278 87.50

SEQ ID NO 1088 2295088 100.00 SEQ ID NO 1136 2331287 90.00

SEQ ID NO 1089 2298561 100.00 SEQ ID NO 1137 2331307 100.00

SEQ ID NO 1090 2299967 78.57 SEQ ID NO 1138 2331709 75.00

SEQ ID NO 1091 2301677 92.86 SEQ ID NO 1139 2331804 75.00

SEQ ID NO 1092 2304849 90.00 SEQ ID NO 1140 2331828 75.00

SEQ ID NO 1093 2305094 90.00 SEQ ID NO 1141 2333541 91.67

SEQ ID NO 1094 2305134 83.33 SEQ ID NO 1142 2333752 92.86 SEQ ID NO 1143 2333935 90.00 SEQ ID NO 1191 2373047 100.00

SEQ ID NO 1144 2334113 100.00 SEQ ID NO 1192 2374543 100.00

SEQ ID NO 1145 2334147 87.50 SEQ ID NO 1193 2376281 85.71

SEQ ID NO 1146 2334165 100.00 SEQ ID NO 1194 2376467 100.00

SEQ ID NO 1147 2334489 92.31 SEQ ID NO 1195 2377332 100.00

SEQ ID NO 1148 2334578 92.86 SEQ ID NO 1196 2378563 86.67

SEQ ID NO 1149 2334763 81.82 SEQ ID NO 1197 2379011 100.00

SEQ ID NO 1150 2334813 92.86 SEQ ID NO 1198 2379221 100.00

SEQ ID NO 1151 2335398 91.67 SEQ ID NO 1199 2379981 100.00

SEQ ID NO 1152 2335424 90.91 SEQ ID NO 1200 2380090 100.00

SEQ ID NO 1153 2335446 92.31 SEQ ID NO 1201 2380153 100.00

SEQ ID NO 1154 2335513 92.86 SEQ ID NO 1202 2380323 100.00

SEQ ID NO 1155 2335657 100.00 SEQ ID NO 1203 2380671 87.50

SEQ ID NO 1156 2335777 100.00 SEQ ID NO 1204 2380673 88.89

SEQ ID NO 1157 2340297 100.00 SEQ ID NO 1205 2381045 100.00

SEQ ID NO 1158 2340421 100.00 SEQ ID NO 1206 2381092 100.00

SEQ ID NO 1159 2340530 83.33 SEQ ID NO 1207 2382639 100.00

SEQ ID NO 1160 2344620 100.00 SEQ ID NO 1208 2382711 100.00

SEQ ID NO 1161 2344702 85.71 SEQ ID NO 1209 2383968 100.00

SEQ ID NO 1162 2344879 85.71 SEQ ID NO 1210 2384459 83.33

SEQ ID NO 1163 2345907 93.33 SEQ ID NO 1211 2384475 100.00

SEQ ID NO 1164 2346121 100.00 SEQ ID NO 1212 2384488 100.00

SEQ ID NO 1165 2350623 100.00 SEQ ID NO 1213 2384504 92.86

SEQ ID NO 1166 2350948 100.00 SEQ ID NO 1214 2384716 92.86

SEQ ID NO 1167 2351053 100.00 SEQ ID NO 1215 2385190 80.00

SEQ ID NO 1168 2351176 100.00 SEQ ID NO 1216 2385309 83.33

SEQ ID NO 1169 2351250 100.00 SEQ ID NO 1217 2385361 75.00

SEQ ID NO 1170 2358066 100.00 SEQ ID NO 1218 2385433 83.33

SEQ ID NO 1171 2358153 100.00 SEQ ID NO 1219 2385562 92.31

SEQ ID NO 1172 2358717 100.00 SEQ ID NO 1220 2385672 92.31

SEQ ID NO 1173 2359359 100.00 SEQ ID NO 1221 2385747 100.00

SEQ ID NO 1174 2360108 93.33 SEQ ID NO 1222 2385776 100.00

SEQ ID NO 1175 2360115 100.00 SEQ ID NO 1223 2385794 100.00

SEQ ID NO 1176 2360133 75.00 SEQ ID NO 1224 2385827 100.00

SEQ ID NO 1177 2360259 90.00 SEQ ID NO 1225 2385833 92.31

SEQ ID NO 1178 2360520 100.00 SEQ ID NO 1226 2385989 100.00

SEQ ID NO 1179 2365303 100.00 SEQ ID NO 1227 2386033 100.00

SEQ ID NO 1180 2365443 100.00 SEQ ID NO 1228 2386393 88.89

SEQ ID NO 1181 2366224 100.00 SEQ ID NO 1229 2389149 92.86

SEQ ID NO 1182 2366648 100.00 SEQ ID NO 1230 2389173 100.00

SEQ ID NO 1183 2368406 100.00 SEQ ID NO 1231 2389328 88.89

SEQ ID NO 1184 2368539 100.00 SEQ ID NO 1232 2389331 83.33

SEQ ID NO 1185 2368870 100.00 SEQ ID NO 1233 2389407 100.00

SEQ ID NO 1186 2368894 100.00 SEQ ID NO 1234 2389599 100.00

SEQ ID NO 1187 2369318 100.00 SEQ ID NO 1235 2390057 100.00

SEQ ID NO 1188 2369746 100.00 SEQ ID NO 1236 2390320 75.00

SEQ ID NO 1189 2369997 100.00 SEQ ID NO 1237 2390474 100.00

SEQ ID NO 1190 2370267 100.00 SEQ ID NO 1238 2390480 100.00 SEQ ID NO 1239 2391012 85.71 SEQ ID NO 1287 2430312 100.00

SEQ ID NO 1240 2391375 80.00 SEQ ID NO 1288 2432948 100.00

SEQ ID NO 1241 2391409 85.71 SEQ ID NO 1289 2433656 100.00

SEQ ID NO 1242 2391440 83.33 SEQ ID NO 1290 2446336 75.00

SEQ ID NO 1243 2392577 80.00 SEQ ID NO 1291 2448434 100.00

SEQ ID NO 1244 2392665 80.00 SEQ ID NO 1292 2448479 85.71

SEQ ID NO 1245 2393534 100.00 SEQ ID NO 1293 2448564 100.00

SEQ ID NO 1246 2393590 100.00 SEQ ID NO 1294 2456798 100.00

SEQ ID NO 1247 2394452 80.00 SEQ ID NO 1295 2456933 100.00

SEQ ID NO 1248 2394472 100.00 SEQ ID NO 1296 2459168 75.00

SEQ ID NO 1249 2394557 83.33 SEQ ID NO 1297 2459770 100.00

SEQ ID NO 1250 2394647 100.00 SEQ ID NO 1298 2461304 100.00

SEQ ID NO 1251 2395010 100.00 SEQ ID NO 1299 2461334 100.00

SEQ ID NO 1252 2395466 100.00 SEQ ID NO 1300 2461480 100.00

SEQ ID NO 1253 2395480 75.00 SEQ ID NO 1301 2461540 100.00

SEQ ID NO 1254 2396031 85.71 SEQ ID NO 1302 2461889 100.00

SEQ ID NO 1255 2399330 91.67 SEQ ID NO 1303 2462667 100.00

SEQ ID NO 1256 2399993 80.00 SEQ ID NO 1304 2462696 75.00

SEQ ID NO 1257 2400706 81.82 SEQ ID NO 1305 2462884 83.33

SEQ ID NO 1258 2400753 93.33 SEQ ID NO 1306 2462987 75.00

SEQ ID NO 1259 2400938 92.86 SEQ ID NO 1307 2463092 90.00

SEQ ID NO 1260 2401015 92.86 SEQ ID NO 1308 2463107 83.33

SEQ ID NO 1261 2401063 91.67 SEQ ID NO 1309 2463148 80.00

SEQ ID NO 1262 2409637 83.33 SEQ ID NO 1310 2463193 100.00

SEQ ID NO 1263 2414680 92.31 SEQ ID NO 1311 2463293 100.00

SEQ ID NO 1264 2414934 83.33 SEQ ID NO 1312 2465619 90.00

SEQ ID NO 1265 2414955 88.89 SEQ ID NO 1313 2468436 92.86

SEQ ID NO 1266 2414959 87.50 SEQ ID NO 1314 2468447 92.86

SEQ ID NO 1267 2414961 80.00 SEQ ID NO 1315 2468731 92.86

SEQ ID NO 1268 2414967 88.89 SEQ ID NO 1316 2468738 92.86

SEQ ID NO 1269 2415463 87.50 SEQ ID NO 1317 2468800 92.86

SEQ ID NO 1270 2416709 85.71 SEQ ID NO 1318 2469004 92.86

SEQ ID NO 1271 2416769 90.00 SEQ ID NO 1319 2472117 100.00

SEQ ID NO 1272 2417008 100.00 SEQ ID NO 1320 2474424 75.00

SEQ ID NO 1273 2417794 75.00 SEQ ID NO 1321 2475630 100.00

SEQ ID NO 1274 2418144 91.67 SEQ ID NO 1322 2475651 100.00

SEQ ID NO 1275 2420705 75.00 SEQ ID NO 1323 2475776 100.00

SEQ ID NO 1276 2421559 100.00 SEQ ID NO 1324 2475795 100.00

SEQ ID NO 1277 2423560 83.33 SEQ ID NO 1325 2475895 100.00

SEQ ID NO 1278 2423608 83.33 SEQ ID NO 1326 2476106 100.00

SEQ ID NO 1279 2423769 90.00 SEQ ID NO 1327 2477363 100.00

SEQ ID NO 1280 2423832 100.00 SEQ ID NO 1328 2477614 100.00

SEQ ID NO 1281 2424018 100.00 SEQ ID NO 1329 2478703 100.00

SEQ ID NO 1282 2424044 100.00 SEQ ID NO 1330 2478933 92.31

SEQ ID NO 1283 2424147 100.00 SEQ ID NO 1331 2478934 91.67

SEQ ID NO 1284 2424673 75.00 SEQ ID NO 1332 2478961 88.89

SEQ ID NO 1285 2424679 100.00 SEQ ID NO 1333 2479060 92.86

SEQ ID NO 1286 2424826 75.00 SEQ ID NO 1334 2479140 92.31 SEQ ID NO 1335 2479160 83.33 SEQ ID NO 1383 2521923 93.33

SEQ ID NO 1336 2479212 92.86 SEQ ID NO 1384 2522735 93.33

SEQ ID NO 1337 2479255 100.00 SEQ ID NO 1385 2522873 100.00

SEQ ID NO 1338 2479261 92.86 SEQ ID NO 1386 2524933 100.00

SEQ ID NO 1339 2479329 92.86 SEQ ID NO 1387 2524993 100.00

SEQ ID NO 1340 2479382 92.86 SEQ ID NO 1388 2525274 100.00

SEQ ID NO 1341 2479438 92.86 SEQ ID NO 1389 2525339 92.31

SEQ ID NO 1342 2479508 92.86 SEQ ID NO 1390 2525712 100.00

SEQ ID NO 1343 2479651 90.00 SEQ ID NO 1391 2525717 100.00

SEQ ID NO 1344 2480797 90.91 SEQ ID NO 1392 2528733 80.00

SEQ ID NO 1345 2480819 80.00 SEQ ID NO 1393 2535648 90.00

SEQ ID NO 1346 2480922 90.00 SEQ ID NO 1394 2537265 100.00

SEQ ID NO 1347 2481010 93.33 SEQ ID NO 1395 2537353 85.71

SEQ ID NO 1348 2481927 100.00 SEQ ID NO 1396 2537492 93.33

SEQ ID NO 1349 2484674 100.00 SEQ ID NO 1397 2538379 76.92

SEQ ID NO 1350 2484836 100.00 SEQ ID NO 1398 2539049 100.00

SEQ ID NO 1351 2485072 100.00 SEQ ID NO 1399 2539269 93.33

SEQ ID NO 1352 2485088 100.00 SEQ ID NO 1400 2539862 100.00

SEQ ID NO 1353 2485098 100.00 SEQ ID NO 1401 2539921 100.00

SEQ ID NO 1354 2485171 87.50 SEQ ID NO 1402 2540050 100.00

SEQ ID NO 1355 2485303 100.00 SEQ ID NO 1403 2540124 100.00

SEQ ID NO 1356 2485516 83.33 SEQ ID NO 1404 2540226 100.00

SEQ ID NO 1357 2487627 100.00 SEQ ID NO 1405 2540305 85.71

SEQ ID NO 1358 2488228 100.00 SEQ ID NO 1406 2540322 100.00

SEQ ID NO 1359 2490962 100.00 SEQ ID NO 1407 2540365 100.00

SEQ ID NO 1360 2491541 92.86 SEQ ID NO 1408 2540419 100.00

SEQ ID NO 1361 2492233 75.00 SEQ ID NO 1409 2540471 100.00

SEQ ID NO 1362 2492427 100.00 SEQ ID NO 1410 2540483 100.00

SEQ ID NO 1363 2492429 100.00 SEQ ID NO 1411 2540484 100.00

SEQ ID NO 1364 2501202 75.00 SEQ ID NO 1412 2540521 100.00

SEQ ID NO 1365 2502033 93.33 SEQ ID NO 1413 2540534 100.00

SEQ ID NO 1366 2502145 100.00 SEQ ID NO 1414 2540914 100.00

SEQ ID NO 1367 2502153 90.91 SEQ ID NO 1415 2540996 100.00

SEQ ID NO 1368 2502209 100.00 SEQ ID NO 1416 2541270 100.00

SEQ ID NO 1369 2502405 100.00 SEQ ID NO 1417 2541459 100.00

SEQ ID NO 1370 2504377 100.00 SEQ ID NO 1418 2541531 100.00

SEQ ID NO 1371 2504382 100.00 SEQ ID NO 1419 2541621 100.00

SEQ ID NO 1372 2504490 100.00 SEQ ID NO 1420 2541661 100.00

SEQ ID NO 1373 2504514 75.00 SEQ ID NO 1421 2541731 100.00

SEQ ID NO 1374 2504560 100.00 SEQ ID NO 1422 2542613 100.00

SEQ ID NO 1375 2504603 100.00 SEQ ID NO 1423 2546117 100.00

SEQ ID NO 1376 2514450 92.86 SEQ ID NO 1424 2546365 100.00

SEQ ID NO 1377 2514655 100.00 SEQ ID NO 1425 2547131 100.00

SEQ ID NO 1378 2514723 100.00 SEQ ID NO 1426 2547309 100.00

SEQ ID NO 1379 2515198 100.00 SEQ ID NO 1427 2547410 100.00

SEQ ID NO 1380 2521257 92.86 SEQ ID NO 1428 2548417 100.00

SEQ ID NO 1381 2521631 72.73 SEQ ID NO 1429 2550426 100.00

SEQ ID NO 1382 2521633 84.62 SEQ ID NO 1430 2550499 100.00 SEQ ID NO 1431 2550670 100.00 SEQ ID NO 1479 2586405 93.33

SEQ ID NO 1432 2550737 100.00 SEQ ID NO 1480 2586409 93.33

SEQ ID NO 1433 2551488 100.00 SEQ ID NO 1481 2586436 93.33

SEQ ID NO 1434 2552089 100.00 SEQ ID NO 1482 2586597 93.33

SEQ ID NO 1435 2552311 100.00 SEQ ID NO 1483 2587596 75.00

SEQ ID NO 1436 2552392 100.00 SEQ ID NO 1484 2587733 75.00

SEQ ID NO 1437 2552429 100.00 SEQ ID NO 1485 2587913 100.00

SEQ ID NO 1438 2552430 100.00 SEQ ID NO 1486 2587925 100.00

SEQ ID NO 1439 2552467 100.00 SEQ ID NO 1487 2587932 100.00

SEQ ID NO 1440 2552480 100.00 SEQ ID NO 1488 2587937 100.00

SEQ ID NO 1441 2552920 100.00 SEQ ID NO 1489 2587967 100.00

SEQ ID NO 1442 2553007 100.00 SEQ ID NO 1490 2588020 80.00

SEQ ID NO 1443 2553362 81.82 SEQ ID NO 1491 2588030 90.91

SEQ ID NO 1444 2553462 92.31 SEQ ID NO 1492 2588039 80.00

SEQ ID NO 1445 2555920 87.50 SEQ ID NO 1493 2588048 80.00

SEQ ID NO 1446 2556452 100.00 SEQ ID NO 1494 2588113 87.50

SEQ ID NO 1447 2556686 88.89 SEQ ID NO 1495 2588155 92.31

SEQ ID NO 1448 2557977 90.00 SEQ ID NO 1496 2588358 93.33

SEQ ID NO 1449 2558056 80.00 SEQ ID NO 1497 2588518 100.00

SEQ ID NO 1450 2558166 100.00 SEQ ID NO 1498 2588610 80.00

SEQ ID NO 1451 2558484 93.33 SEQ ID NO 1499 2588677 80.00

SEQ ID NO 1452 2558731 100.00 SEQ ID NO 1500 2588690 75.00

SEQ ID NO 1453 2559219 100.00 SEQ ID NO 1501 2588708 91.67

SEQ ID NO 1454 2559423 100.00 SEQ ID NO 1502 2588967 100.00

SEQ ID NO 1455 2559499 100.00 SEQ ID NO 1503 2588989 100.00

SEQ ID NO 1456 2559576 100.00 SEQ ID NO 1504 2589092 83.33

SEQ ID NO 1457 2560301 92.86 SEQ ID NO 1505 2590772 100.00

SEQ ID NO 1458 2560312 100.00 SEQ ID NO 1506 2590825 100.00

SEQ ID NO 1459 2560475 92.86 SEQ ID NO 1507 2591041 93.33

SEQ ID NO 1460 2560510 93.33 SEQ ID NO 1508 2591121 100.00

SEQ ID NO 1461 2563966 93.33 SEQ ID NO 1509 2591167 93.33

SEQ ID NO 1462 2564210 75.00 SEQ ID NO 1510 2591246 93.33

SEQ ID NO 1463 2564258 93.33 SEQ ID NO 1511 2591359 92.31

SEQ ID NO 1464 2569665 93.33 SEQ ID NO 1512 2591406 93.33

SEQ ID NO 1465 2569814 93.33 SEQ ID NO 1513 2591649 75.00

SEQ ID NO 1466 2573506 100.00 SEQ ID NO 1514 2592210 90.00

SEQ ID NO 1467 2573968 100.00 SEQ ID NO 1515 2592237 90.00

SEQ ID NO 1468 2574034 75.00 SEQ ID NO 1516 2592244 75.00

SEQ ID NO 1469 2574198 85.71 SEQ ID NO 1517 2592321 75.00

SEQ ID NO 1470 2574434 75.00 SEQ ID NO 1518 2593614 100.00

SEQ ID NO 1471 2574525 87.50 SEQ ID NO 1519 2593712 100.00

SEQ ID NO 1472 2579449 100.00 SEQ ID NO 1520 2594488 83.33

SEQ ID NO 1473 2581966 93.33 SEQ ID NO 1521 2594504 100.00

SEQ ID NO 1474 2582931 93.33 SEQ ID NO 1522 2597221 100.00

SEQ ID NO 1475 2583076 93.33 SEQ ID NO 1523 2597307 100.00

SEQ ID NO 1476 2583093 93.33 SEQ ID NO 1524 2597324 100.00

SEQ ID NO 1477 2583252 90.91 SEQ ID NO 1525 2597352 100.00

SEQ ID NO 1478 2584919 75.00 SEQ ID NO 1526 2598668 100.00 SEQ ID NO 1527 2598701 75.00 SEQ ID NO 1575 2619649 93.33

SEQ ID NO 1528 2598850 90.00 SEQ ID NO 1576 2619692 93.33

SEQ ID NO 1529 2598979 86.67 SEQ ID NO 1577 2619713 93.33

SEQ ID NO 1530 2599143 88.89 SEQ ID NO 1578 2619714 93.33

SEQ ID NO 1531 2599173 87.50 SEQ ID NO 1579 2619737 93.33

SEQ ID NO 1532 2600795 100.00 SEQ ID NO 1580 2619896 93.33

SEQ ID NO 1533 2600890 71.43 SEQ ID NO 1581 2620059 93.33

SEQ ID NO 1534 2601190 87.50 SEQ ID NO 1582 2620612 75.00

SEQ ID NO 1535 2601836 75.00 SEQ ID NO 1583 2620800 93.33

SEQ ID NO 1536 2606344 93.33 SEQ ID NO 1584 2622309 83.33

SEQ ID NO 1537 2607382 91.67 SEQ ID NO 1585 2622316 92.86

SEQ ID NO 1538 2607468 93.33 SEQ ID NO 1586 2622607 93.33

SEQ ID NO 1539 2607551 93.33 SEQ ID NO 1587 2623048 80.00

SEQ ID NO 1540 2607740 80.00 SEQ ID NO 1588 2623421 93.33

SEQ ID NO 1541 2608780 85.71 SEQ ID NO 1589 2624290 93.33

SEQ ID NO 1542 2611536 93.33 SEQ ID NO 1590 2624577 80.00

SEQ ID NO 1543 2611575 93.33 SEQ ID NO 1591 2624615 93.33

SEQ ID NO 1544 2611879 93.33 SEQ ID NO 1592 2624776 80.00

SEQ ID NO 1545 2611994 85.71 SEQ ID NO 1593 2625313 83.33

SEQ ID NO 1546 2612717 80.00 SEQ ID NO 1594 2625982 93.33

SEQ ID NO 1547 2613634 92.86 SEQ ID NO 1595 2626859 80.00

SEQ ID NO 1548 2614113 93.33 SEQ ID NO 1596 2626978 93.33

SEQ ID NO 1549 2614169 75.00 SEQ ID NO 1597 2627041 80.00

SEQ ID NO 1550 2614779 80.00 SEQ ID NO 1598 2637302 88.89

SEQ ID NO 1551 2614801 93.33 SEQ ID NO 1599 2637308 93.33

SEQ ID NO 1552 2615019 92.86 SEQ ID NO 1600 2637762 93.33

SEQ ID NO 1553 2615119 93.33 SEQ ID NO 1601 2640289 100.00

SEQ ID NO 1554 2615148 92.31 SEQ ID NO 1602 2642187 80.00

SEQ ID NO 1555 2615220 80.00 SEQ ID NO 1603 2642744 83.33

SEQ ID NO 1556 2615311 93.33 SEQ ID NO 1604 2642801 100.00

SEQ ID NO 1557 2615392 93.33 SEQ ID NO 1605 2643190 100.00

SEQ ID NO 1558 2615483 93.33 SEQ ID NO 1606 2643192 100.00

SEQ ID NO 1559 2615507 93.33 SEQ ID NO 1607 2646134 100.00

SEQ ID NO 1560 2615565 75.00 SEQ ID NO 1608 2647083 100.00

SEQ ID NO 1561 2615567 75.00 SEQ ID NO 1609 2647098 86.67

SEQ ID NO 1562 2615803 100.00 SEQ ID NO 1610 2647117 92.86

SEQ ID NO 1563 2616187 88.89 SEQ ID NO 1611 2647125 92.31

SEQ ID NO 1564 2616413 93.33 SEQ ID NO 1612 2647152 90.00

SEQ ID NO 1565 2616718 75.00 SEQ ID NO 1613 2647373 100.00

SEQ ID NO 1566 2616937 91.67 SEQ ID NO 1614 2647430 91.67

SEQ ID NO 1567 2616976 93.33 SEQ ID NO 1615 2648279 100.00

SEQ ID NO 1568 2617211 75.00 SEQ ID NO 1616 2648292 100.00

SEQ ID NO 1569 2617386 93.33 SEQ ID NO 1617 2648414 100.00

SEQ ID NO 1570 2617934 93.33 SEQ ID NO 1618 2648442 100.00

SEQ ID NO 1571 2618594 93.33 SEQ ID NO 1619 2648493 83.33

SEQ ID NO 1572 2618791 75.00 SEQ ID NO 1620 2648535 85.71

SEQ ID NO 1573 2618982 93.33 SEQ ID NO 1621 2648765 100.00

SEQ ID NO 1574 2619618 93.33 SEQ ID NO 1622 2648966 100.00 SEQ ID NO 1623 2649685 100.00 SEQ ID NO 1671 2659468 100.00

SEQ ID NO 1624 2649954 87.50 SEQ ID NO 1672 2659480 75.00

SEQ ID NO 1625 2650161 80.00 SEQ ID NO 1673 2659517 92.86

SEQ ID NO 1626 2653070 93.33 SEQ ID NO 1674 2659562 93.33

SEQ ID NO 1627 2653270 93.33 SEQ ID NO 1675 2659569 93.33

SEQ ID NO 1628 2654475 93.33 SEQ ID NO 1676 2659588 80.00

SEQ ID NO 1629 2657427 75.00 SEQ ID NO 1677 2659668 93.33

SEQ ID NO 1630 2657455 75.00 SEQ ID NO 1678 2659783 93.33

SEQ ID NO 1631 2657466 91.67 SEQ ID NO 1679 2659837 93.33

SEQ ID NO 1632 2657484 80.00 SEQ ID NO 1680 2659877 93.33

SEQ ID NO 1633 2657566 90.00 SEQ ID NO 1681 2659906 91.67

SEQ ID NO 1634 2657572 75.00 SEQ ID NO 1682 2660156 90.91

SEQ ID NO 1635 2657594 87.50 SEQ ID NO 1683 2660399 92.86

SEQ ID NO 1636 2657608 85.71 SEQ ID NO 1684 2660405 93.33

SEQ ID NO 1637 2657754 93.33 SEQ ID NO 1685 2660453 91.67

SEQ ID NO 1638 2657881 93.33 SEQ ID NO 1686 2660458 93.33

SEQ ID NO 1639 2657888 83.33 SEQ ID NO 1687 2660477 93.33

SEQ ID NO 1640 2657915 90.00 SEQ ID NO 1688 2660486 100.00

SEQ ID NO 1641 2657921 87.50 SEQ ID NO 1689 2660558 75.00

SEQ ID NO 1642 2657961 93.33 SEQ ID NO 1690 2660604 75.00

SEQ ID NO 1643 2658001 87.50 SEQ ID NO 1691 2660640 75.00

SEQ ID NO 1644 2658041 93.33 SEQ ID NO 1692 2660690 75.00

SEQ ID NO 1645 2658055 93.33 SEQ ID NO 1693 2660707 100.00

SEQ ID NO 1646 2658071 87.50 SEQ ID NO 1694 2660714 75.00

SEQ ID NO 1647 2658087 75.00 SEQ ID NO 1695 2661635 75.00

SEQ ID NO 1648 2658090 75.00 SEQ ID NO 1696 2661648 90.00

SEQ ID NO 1649 2658106 100.00 SEQ ID NO 1697 2661664 83.33

SEQ ID NO 1650 2658112 91.67 SEQ ID NO 1698 2661688 88.89

SEQ ID NO 1651 2658119 75.00 SEQ ID NO 1699 2661761 88.89

SEQ ID NO 1652 2658175 75.00 SEQ ID NO 1700 2661889 75.00

SEQ ID NO 1653 2658452 92.31 SEQ ID NO 1701 2661923 75.00

SEQ ID NO 1654 2658568 92.31 SEQ ID NO 1702 2662444 93.33

SEQ ID NO 1655 2658672 90.00 SEQ ID NO 1703 2662460 93.33

SEQ ID NO 1656 2658715 93.33 SEQ ID NO 1704 2662615 75.00

SEQ ID NO 1657 2658792 93.33 SEQ ID NO 1705 2663067 91.67

SEQ ID NO 1658 2658831 93.33 SEQ ID NO 1706 2663318 100.00

SEQ ID NO 1659 2658842 93.33 SEQ ID NO 1707 2666759 93.33

SEQ ID NO 1660 2658856 80.00 SEQ ID NO 1708 2666943 93.33

SEQ ID NO 1661 2658925 93.33 SEQ ID NO 1709 2666987 93.33

SEQ ID NO 1662 2659062 93.33 SEQ ID NO 1710 2666996 93.33

SEQ ID NO 1663 2659082 75.00 SEQ ID NO 1711 2667019 80.00

SEQ ID NO 1664 2659089 93.33 SEQ ID NO 1712 2667040 93.33

SEQ ID NO 1665 2659119 80.00 SEQ ID NO 1713 2667115 93.33

SEQ ID NO 1666 2659169 75.00 SEQ ID NO 1714 2667196 93.33

SEQ ID NO 1667 2659201 93.33 SEQ ID NO 1715 2669411 75.00

SEQ ID NO 1668 2659392 93.33 SEQ ID NO 1716 2670390 90.00

SEQ ID NO 1669 2659422 100.00 SEQ ID NO 1717 2671703 83.33

SEQ ID NO 1670 2659426 92.31 SEQ ID NO 1718 2671721 83.33 SEQ ID NO 1719 2671860 92.86 SEQ ID NO 1767 2692821 100.00

SEQ ID NO 1720 2671952 92.86 SEQ ID NO 1768 2693220 100.00

SEQ ID NO 1721 2672101 80.00 SEQ ID NO 1769 2693656 100.00

SEQ ID NO 1722 2672133 75.00 SEQ ID NO 1770 2694324 75.00

SEQ ID NO 1723 2672147 85.71 SEQ ID NO 1771 2694419 75.00

SEQ ID NO 1724 2672637 75.00 SEQ ID NO 1772 2695621 83.33

SEQ ID NO 1725 2672670 90.91 SEQ ID NO 1773 2696320 92.31

SEQ ID NO 1726 2672686 93.33 SEQ ID NO 1774 2696419 92.86

SEQ ID NO 1727 2672774 93.33 SEQ ID NO 1775 2696455 92.31

SEQ ID NO 1728 2672821 93.33 SEQ ID NO 1776 2696742 92.86

SEQ ID NO 1729 2672827 93.33 SEQ ID NO 1777 2697123 92.86

SEQ ID NO 1730 2672942 93.33 SEQ ID NO 1778 2697515 100.00

SEQ ID NO 1731 2673011 93.33 SEQ ID NO 1779 2697628 92.86

SEQ ID NO 1732 2673015 75.00 SEQ ID NO 1780 2697672 92.86

SEQ ID NO 1733 2673029 93.33 SEQ ID NO 1781 2697690 92.86

SEQ ID NO 1734 2673041 92.86 SEQ ID NO 1782 2697789 100.00

SEQ ID NO 1735 2673894 75.00 SEQ ID NO 1783 2697808 86.67

SEQ ID NO 1736 2673970 93.33 SEQ ID NO 1784 2698015 92.86

SEQ ID NO 1737 2673990 83.33 SEQ ID NO 1785 2698544 100.00

SEQ ID NO 1738 2674015 93.33 SEQ ID NO 1786 2699193 92.86

SEQ ID NO 1739 2674160 93.33 SEQ ID NO 1787 2699392 81.82

SEQ ID NO 1740 2674412 93.33 SEQ ID NO 1788 2699512 80.00

SEQ ID NO 1741 2674508 93.33 SEQ ID NO 1789 2700047 100.00

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SEQ ID NO 1743 2675777 93.33 SEQ ID NO 1791 2700676 77.78

SEQ ID NO 1744 2675799 80.00 SEQ ID NO 1792 2701250 85.71

SEQ ID NO 1745 2675813 93.33 SEQ ID NO 1793 2701260 100.00

SEQ ID NO 1746 2675842 93.33 SEQ ID NO 1794 2701618 81.82

SEQ ID NO 1747 2675873 93.33 SEQ ID NO 1795 2701806 81.82

SEQ ID NO 1748 2675887 80.00 SEQ ID NO 1796 2701860 85.71

SEQ ID NO 1749 2675889 88.89 SEQ ID NO 1797 2701949 87.50

SEQ ID NO 1750 2676973 93.33 SEQ ID NO 1798 2701977 75.00

SEQ ID NO 1751 2676991 75.00 SEQ ID NO 1799 2702090 100.00

SEQ ID NO 1752 2677128 93.33 SEQ ID NO 1800 2702234 80.00

SEQ ID NO 1753 2677332 87.50 SEQ ID NO 1801 2703703 100.00

SEQ ID NO 1754 2677509 93.33 SEQ ID NO 1802 2704094 92.86

SEQ ID NO 1755 2677729 93.33 SEQ ID NO 1803 2704569 86.67

SEQ ID NO 1756 2680577 100.00 SEQ ID NO 1804 2704809 100.00

SEQ ID NO 1757 2681547 100.00 SEQ ID NO 1805 2704977 100.00

SEQ ID NO 1758 2681708 100.00 SEQ ID NO 1806 2705287 92.86

SEQ ID NO 1759 2682064 100.00 SEQ ID NO 1807 2705425 92.86

SEQ ID NO 1760 2682551 100.00 SEQ ID NO 1808 2705457 93.33

SEQ ID NO 1761 2684158 100.00 SEQ ID NO 1809 2705625 91.67

SEQ ID NO 1762 2684346 92.86 SEQ ID NO 1810 2705716 92.86

SEQ ID NO 1763 2684614 100.00 SEQ ID NO 1811 2705829 92.86

SEQ ID NO 1764 2684779 100.00 SEQ ID NO 1812 2706129 100.00

SEQ ID NO 1765 2684832 75.00 SEQ ID NO 1813 2706394 92.86

SEQ ID NO 1766 2692682 100.00 SEQ ID NO 1814 2706986 75.00 SEQ ID NO 1815 2706996 93.33 SEQ ID NO 1863 2757381 87.50

SEQ ID NO 1816 2707022 75.00 SEQ ID NO 1864 2758924 100.00

SEQ ID NO 1817 2707027 75.00 SEQ ID NO 1865 2759373 90.00

SEQ ID NO 1818 2707029 75.00 SEQ ID NO 1866 2759396 100.00

SEQ ID NO 1819 2707386 75.00 SEQ ID NO 1867 2759407 100.00

SEQ ID NO 1820 2709036 92.86 SEQ ID NO 1868 2759882 100.00

SEQ ID NO 1821 2709195 87.50 SEQ ID NO 1869 2760001 90.91

SEQ ID NO 1822 2709226 100.00 SEQ ID NO 1870 2760488 100.00

SEQ ID NO 1823 2709271 92.86 SEQ ID NO 1871 2761649 100.00

SEQ ID NO 1824 2709361 92.86 SEQ ID NO 1872 2762392 100.00

SEQ ID NO 1825 2709412 92.31 SEQ ID NO 1873 2762986 100.00

SEQ ID NO 1826 2709505 92.31 SEQ ID NO 1874 2763467 100.00

SEQ ID NO 1827 2709600 92.86 SEQ ID NO 1875 2763672 100.00

SEQ ID NO 1828 2710135 80.00 SEQ ID NO 1876 2763903 100.00

SEQ ID NO 1829 2710335 83.33 SEQ ID NO 1877 2764129 100.00

SEQ ID NO 1830 2710611 83.33 SEQ ID NO 1878 2764137 100.00

SEQ ID NO 1831 2711702 100.00 SEQ ID NO 1879 2764194 100.00

SEQ ID NO 1832 2713737 86.67 SEQ ID NO 1880 2764301 100.00

SEQ ID NO 1833 2714237 92.31 SEQ ID NO 1881 2764750 92.31

SEQ ID NO 1834 2717902 75.00 SEQ ID NO 1882 2764844 92.86

SEQ ID NO 1835 2723337 100.00 SEQ ID NO 1883 2765021 100.00

SEQ ID NO 1836 2723548 100.00 SEQ ID NO 1884 2765159 100.00

SEQ ID NO 1837 2729511 100.00 SEQ ID NO 1885 2765547 100.00

SEQ ID NO 1838 2729645 100.00 SEQ ID NO 1886 2766034 100.00

SEQ ID NO 1839 2730395 100.00 SEQ ID NO 1887 2766738 100.00

SEQ ID NO 1840 2730959 83.33 SEQ ID NO 1888 2766886 100.00

SEQ ID NO 1841 2731515 80.00 SEQ ID NO 1889 2770699 100.00

SEQ ID NO 1842 2732100 100.00 SEQ ID NO 1890 2771532 80.00

SEQ ID NO 1843 2732121 100.00 SEQ ID NO 1891 2771811 100.00

SEQ ID NO 1844 2732976 100.00 SEQ ID NO 1892 2772185 100.00

SEQ ID NO 1845 2738118 87.50 SEQ ID NO 1893 2773429 100.00

SEQ ID NO 1846 2738344 100.00 SEQ ID NO 1894 2774046 100.00

SEQ ID NO 1847 2738717 100.00 SEQ ID NO 1895 2774175 100.00

SEQ ID NO 1848 2739271 100.00 SEQ ID NO 1896 2774528 100.00

SEQ ID NO 1849 2747412 100.00 SEQ ID NO 1897 2774544 100.00

SEQ ID NO 1850 2747449 100.00 SEQ ID NO 1898 2774612 100.00

SEQ ID NO 1851 2747858 100.00 SEQ ID NO 1899 2774668 100.00

SEQ ID NO 1852 2748042 100.00 SEQ ID NO 1900 2774909 86.67

SEQ ID NO 1853 2748145 100.00 SEQ ID NO 1901 2774985 100.00

SEQ ID NO 1854 2748212 100.00 SEQ ID NO 1902 2775006 100.00

SEQ ID NO 1855 2748260 100.00 SEQ ID NO 1903 2775153 100.00

SEQ ID NO 1856 2748392 100.00 SEQ ID NO 1904 2775161 100.00

SEQ ID NO 1857 2751609 100.00 SEQ ID NO 1905 2775203 100.00

SEQ ID NO 1858 2752928 86.67 SEQ ID NO 1906 2775237 100.00

SEQ ID NO 1859 2753110 92.86 SEQ ID NO 1907 2775336 100.00

SEQ ID NO 1860 2754075 93.33 SEQ ID NO 1908 2775343 100.00

SEQ ID NO 1861 2754177 88.89 SEQ ID NO 1909 2775355 100.00

SEQ ID NO 1862 2754311 100.00 SEQ ID NO 1910 2775380 100.00 SEQ ID NO 1911 2775419 100.00 SEQ ID NO: 1959 2788535 100.00

SEQ ID NO 1912 2775495 77.78 SEQ ID NO: 1960 2788605 100.00

SEQ ID NO 1913 2775512 100.00 SEQ ID NO: 1961 2789415 100.00

SEQ ID NO 1914 2776504 93.33 SEQ ID NO: 1962 2789579 100.00

SEQ ID NO 1915 2776657 100.00 SEQ ID NO: 1963 2789764 92.86

SEQ ID NO 1916 2776968 100.00 SEQ ID NO: 1964 2789963 92.86

SEQ ID NO 1917 2777246 100.00 SEQ ID NO: 1965 2790084 91.67

SEQ ID NO 1918 2777319 100.00 SEQ ID NO: 1966 2790119 92.86

SEQ ID NO 1919 2777376 92.31 SEQ ID NO: 1967 2790273 100.00

SEQ ID NO 1920 2777521 100.00 SEQ ID NO: 1968 2790277 92.86

SEQ ID NO 1921 2777736 100.00 SEQ ID NO: 1969 2790293 92.86

SEQ ID NO 1922 2777949 100.00 SEQ ID NO: 1970 2790304 92.86

SEQ ID NO 1923 2778183 100.00 SEQ ID NO: 1971 2790331 92.86

SEQ ID NO 1924 2779456 92.86 SEQ ID NO: 1972 2790438 100.00

SEQ ID NO 1925 2780102 100.00 SEQ ID NO: 1973 2790472 100.00

SEQ ID NO 1926 2780230 100.00 SEQ ID NO: 1974 2790504 92.86

SEQ ID NO 1927 2781060 100.00 SEQ ID NO: 1975 2794263 87.50

SEQ ID NO 1928 2781705 100.00 SEQ ID NO: 1976 2794270 100.00

SEQ ID NO 1929 2782061 100.00 SEQ ID NO: 1977 2794312 100.00

SEQ ID NO 1930 2782303 100.00 SEQ ID NO: 1978 2794339 100.00

SEQ ID NO 1931 2782700 92.86 SEQ ID NO: 1979 2794409 100.00

SEQ ID NO 1932 2782705 100.00 SEQ ID NO: 1980 2794537 91.67

SEQ ID NO 1933 2782725 100.00 SEQ ID NO: 1981 2794777 100.00

SEQ ID NO 1934 2782816 100.00 SEQ ID NO: 1982 2795239 92.86

SEQ ID NO 1935 2782907 100.00 SEQ ID NO: 1983 2795282 92.86

SEQ ID NO 1936 2782927 100.00 SEQ ID NO: 1984 2795380 92.31

SEQ ID NO 1937 2783069 100.00 SEQ ID NO: 1985 2795473 92.86

SEQ ID NO 1938 2783098 100.00 SEQ ID NO: 1986 2795536 92.86

SEQ ID NO 1939 2783247 100.00 SEQ ID NO: 1987 2795573 92.86

SEQ ID NO 1940 2783460 100.00 SEQ ID NO: 1988 2795606 88.89

SEQ ID NO 1941 2784023 100.00 SEQ ID NO: 1989 2795810 92.86

SEQ ID NO 1942 2784025 100.00 SEQ ID NO: 1990 2795825 91.67

SEQ ID NO 1943 2784880 100.00 SEQ ID NO: 1991 2795962 100.00

SEQ ID NO 1944 2785068 100.00 SEQ ID NO: 1992 2796522 100.00

SEQ ID NO 1945 2785580 92.86 SEQ ID NO: 1993 2796537 100.00

SEQ ID NO 1946 2785772 100.00 SEQ ID NO: 1994 2796622 100.00

SEQ ID NO 1947 2785872 100.00 SEQ ID NO: 1995 2796835 100.00

SEQ ID NO 1948 2786030 100.00 SEQ ID NO: 1996 2796896 100.00

SEQ ID NO 1949 2786648 100.00 SEQ ID NO: 1997 2797384 100.00

SEQ ID NO 1950 2786708 100.00 SEQ ID NO: 1998 2797429 100.00

SEQ ID NO 1951 2786826 92.86 SEQ ID NO: 1999 2797454 100.00

SEQ ID NO 1952 2786898 100.00 SEQ ID NO:2000 2797459 100.00

SEQ ID NO 1953 2786918 87.50 SEQ ID NO:2001 2797524 100.00

SEQ ID NO 1954 2786986 100.00 SEQ ID NO:2002 2797664 100.00

SEQ ID NO 1955 2788195 100.00 SEQ ID NO:2003 2797746 100.00

SEQ ID NO 1956 2788284 91.67 SEQ ID NO:2004 2797922 100.00

SEQ ID NO 1957 2788300 100.00 SEQ ID NO:2005 2798267 100.00

SEQ ID NO 1958 2788301 80.00 SEQ ID NO:2006 2798439 100.00 SEQ ID NO:2007 2798471 100.00 SEQ ID NO:2055 2821148 100.00

SEQ ID NO:2008 2798506 100.00 SEQ ID NO:2056 2821339 100.00

SEQ ID NO:2009 2798634 92.31 SEQ ID NO:2057 2821355 88.89

SEQ ID NO:2010 2798802 92.86 SEQ ID NO:2058 2821474 100.00

SEQ ID NO:2011 2798918 100.00 SEQ ID NO:2059 2822337 100.00

SEQ ID NO:2012 2799542 92.86 SEQ ID NO:2060 2822679 91.67

SEQ ID NO:2013 2799555 100.00 SEQ ID NO:2061 2822752 100.00

SEQ ID NO:2014 2799759 100.00 SEQ ID NO:2062 2822761 91.67

SEQ ID NO:2015 2799914 100.00 SEQ ID NO:2063 2822781 92.31

SEQ ID NO:2016 2800014 100.00 SEQ ID NO:2064 2822786 92.86

SEQ ID NO:2017 2800263 100.00 SEQ ID NO:2065 2822801 92.31

SEQ ID NO:2018 2800402 92.86 SEQ ID NO:2066 2822821 91.67

SEQ ID NO:2019 2800467 100.00 SEQ ID NO:2067 2822830 90.00

SEQ ID NO:2020 2801042 100.00 SEQ ID NO:2068 2822893 92.86

SEQ ID NO:2021 2801136 100.00 SEQ ID NO:2069 2822942 90.00

SEQ ID NO:2022 2801307 100.00 SEQ ID NO:2070 2823278 93.33

SEQ ID NO:2023 2801319 100.00 SEQ ID NO:2071 2823308 100.00

SEQ ID NO:2024 2801746 100.00 SEQ ID NO:2072 2823604 92.86

SEQ ID NO:2025 2802040 100.00 SEQ ID NO:2073 2823660 92.86

SEQ ID NO:2026 2802163 100.00 SEQ ID NO:2074 2823960 100.00

SEQ ID NO:2027 2803757 100.00 SEQ ID NO:2075 2824091 92.86

SEQ ID NO:2028 2803947 100.00 SEQ ID NO:2076 2824983 100.00

SEQ ID NO:2029 2804039 100.00 SEQ ID NO:2077 2825147 100.00

SEQ ID NO:2030 2804088 100.00 SEQ ID NO:2078 2825180 100.00

SEQ ID NO:2031 2804186 100.00 SEQ ID NO:2079 2825244 92.86

SEQ ID NO:2032 2804188 92.86 SEQ ID NO:2080 2825679 100.00

SEQ ID NO:2033 2804362 100.00 SEQ ID NO:2081 2825686 100.00

SEQ ID NO:2034 2804682 93.33 SEQ ID NO:2082 2825750 100.00

SEQ ID NO:2035 2804915 92.86 SEQ ID NO:2083 2825812 100.00

SEQ ID NO:2036 2804946 91.67 SEQ ID NO:2084 2825901 100.00

SEQ ID NO:2037 2804956 93.33 SEQ ID NO:2085 2825997 100.00

SEQ ID NO:2038 2805747 100.00 SEQ ID NO:2086 2826002 100.00

SEQ ID NO:2039 2806225 100.00 SEQ ID NO:2087 2826047 100.00

SEQ ID NO:2040 2806411 92.31 SEQ ID NO:2088 2826064 92.31

SEQ ID NO:2041 2806442 92.86 SEQ ID NO:2089 2826174 100.00

SEQ ID NO:2042 2806645 100.00 SEQ ID NO:2090 2826261 100.00

SEQ ID NO:2043 2807318 92.86 SEQ ID NO:2091 2826268 100.00

SEQ ID NO:2044 2807478 92.86 SEQ ID NO:2092 2826303 92.31

SEQ ID NO:2045 2808269 92.86 SEQ ID NO:2093 2830939 85.71

SEQ ID NO:2046 2808841 75.00 SEQ ID NO:2094 2830964 100.00

SEQ ID NO:2047 2810000 100.00 SEQ ID NO:2095 2831891 100.00

SEQ ID NO:2048 2810041 100.00 SEQ ID NO:2096 2831951 100.00

SEQ ID NO:2049 2810088 100.00 SEQ ID NO:2097 2832199 91.67

SEQ ID NO:2050 2812564 92.31 SEQ ID NO:2098 2832262 100.00

SEQ ID NO:2051 2812684 100.00 SEQ ID NO:2099 2832754 100.00

SEQ ID NO:2052 2813005 100.00 SEQ ID NO:2100 2832798 100.00

SEQ ID NO:2053 2813014 100.00 SEQ ID NO:2101 2833050 100.00

SEQ ID NO:2054 2817005 100.00 SEQ ID NO:2102 2833422 100.00 SEQ ID NO:2103 2835782 100.00 SEQ ID NO:2151 2849598 100.00

SEQ ID NO:2104 2836437 100.00 SEQ ID NO:2152 2851887 100.00

SEQ ID NO:2105 2838733 100.00 SEQ ID NO:2153 2851963 100.00

SEQ ID NO:2106 2838744 100.00 SEQ ID NO:2154 2851993 100.00

SEQ ID NO:2107 2839069 100.00 SEQ ID NO:2155 2852151 83.33

SEQ ID NO:2108 2839130 92.31 SEQ ID NO:2156 2852167 100.00

SEQ ID NO:2109 2839188 100.00 SEQ ID NO:2157 2852696 100.00

SEQ ID NO:2110 2839659 100.00 SEQ ID NO:2158 2852885 100.00

SEQ ID N0:2111 2839671 100.00 SEQ ID NO:2159 2852962 100.00

SEQ ID NO:2112 2839711 100.00 SEQ ID NO:2160 2853007 100.00

SEQ ID NO:2113 2839727 93.33 SEQ ID NO:2161 2853082 100.00

SEQ ID NO:2114 2840056 92.86 SEQ ID NO:2162 2853116 100.00

SEQ ID NO:2115 2840119 92.86 SEQ ID NO:2163 2853175 100.00

SEQ ID NO:2116 2840204 100.00 SEQ ID NO:2164 2853191 100.00

SEQ ID NO:2117 2840505 91.67 SEQ ID NO:2165 2853213 100.00

SEQ ID NO:2118 2840684 92.86 SEQ ID NO:2166 2853229 100.00

SEQ ID NO:2119 2840770 92.31 SEQ ID NO:2167 2853236 100.00

SEQ ID NO:2120 2840793 100.00 SEQ ID NO:2168 2853326 100.00

SEQ ID NO:2121 2840956 92.86 SEQ ID NO:2169 2853350 92.31

SEQ ID NO:2122 2841064 92.86 SEQ ID NO:2170 2853467 92.86

SEQ ID NO:2123 2841216 100.00 SEQ ID NO:2171 2853644 88.89

SEQ ID NO:2124 2841615 100.00 SEQ ID NO:2172 2853861 88.89

SEQ ID NO:2125 2841623 80.00 SEQ ID NO:2173 2853882 100.00

SEQ ID NO:2126 2841652 100.00 SEQ ID NO:2174 2854020 100.00

SEQ ID NO:2127 2841731 100.00 SEQ ID NO:2175 2854344 100.00

SEQ ID NO:2128 2841782 100.00 SEQ ID NO:2176 2855159 92.86

SEQ ID NO:2129 2841784 80.00 SEQ ID NO:2177 2855378 100.00

SEQ ID NO:2130 2841871 100.00 SEQ ID NO:2178 2855519 92.86

SEQ ID NO:2131 2842008 100.00 SEQ ID NO:2179 2856124 92.86

SEQ ID NO:2132 2842166 90.91 SEQ ID NO:2180 2856996 91.67

SEQ ID NO:2133 2842171 90.00 SEQ ID NO:2181 2858802 100.00

SEQ ID NO:2134 2842211 100.00 SEQ ID NO:2182 2858865 100.00

SEQ ID NO:2135 2842214 90.91 SEQ ID NO:2183 2859412 92.86

SEQ ID NO:2136 2842215 90.00 SEQ ID NO:2184 2859436 92.86

SEQ ID NO:2137 2842251 80.00 SEQ ID NO:2185 2859459 92.86

SEQ ID NO:2138 2842288 91.67 SEQ ID NO:2186 2859529 92.86

SEQ ID NO:2139 2842299 88.89 SEQ ID NO:2187 2859863 92.86

SEQ ID NO:2140 2842348 100.00 SEQ ID NO:2188 2860132 92.86

SEQ ID NO:2141 2842500 85.71 SEQ ID NO:2189 2860231 92.86

SEQ ID NO:2142 2842533 100.00 SEQ ID NO:2190 2860423 92.86

SEQ ID NO:2143 2842584 84.62 SEQ ID NO:2191 2861708 92.86

SEQ ID NO:2144 2842824 90.91 SEQ ID NO:2192 2861780 92.86

SEQ ID NO:2145 2843098 100.00 SEQ ID NO:2193 2862003 93.33

SEQ ID NO:2146 2843173 100.00 SEQ ID NO:2194 2862319 92.86

SEQ ID NO:2147 2846963 100.00 SEQ ID NO:2195 2862340 92.86

SEQ ID NO:2148 2846994 100.00 SEQ ID NO:2196 2863098 92.31

SEQ ID NO:2149 2849438 100.00 SEQ ID NO:2197 2864144 92.86

SEQ ID NO:2150 2849449 100.00 SEQ ID NO:2198 2864599 92.86 SEQ ID NO:2199 2865716 90.91 SEQ ID NO:2247 2911331 100.00

SEQ ID NO:2200 2876643 85.71 SEQ ID NO:2248 2913031 93.33

SEQ ID NO:2201 2876828 92.86 SEQ ID NO:2249 2913654 75.00

SEQ ID NO:2202 2876852 92.86 SEQ ID NO:2250 2915026 93.33

SEQ ID NO:2203 2877598 92.86 SEQ ID NO:2251 2917579 100.00

SEQ ID NO:2204 2877624 91.67 SEQ ID NO:2252 2926205 100.00

SEQ ID NO:2205 2879865 100.00 SEQ ID NO:2253 2927573 93.33

SEQ ID NO:2206 2880716 100.00 SEQ ID NO:2254 2931960 80.00

SEQ ID NO:2207 2881297 92.86 SEQ ID NO:2255 2933168 93.33

SEQ ID NO:2208 2883647 92.86 SEQ ID NO:2256 2933620 93.33

SEQ ID NO:2209 2886613 100.00 SEQ ID NO:2257 2935480 100.00

SEQ ID NO:2210 2886630 100.00 SEQ ID NO:2258 2936657 100.00

SEQ ID NO:2211 2888505 92.31 SEQ ID NO:2259 2937754 100.00

SEQ ID NO:2212 2889355 83.33 SEQ ID NO:2260 2939964 93.33

SEQ ID NO:2213 2891555 75.00 SEQ ID NO:2261 2942366 80.00

SEQ ID NO:2214 2892115 93.33 SEQ ID NO:2262 2942845 75.00

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SEQ ID NO:2513 3037700 78.57 SEQ ID NO:2561 3063238 73.33

SEQ ID NO:2514 3039557 92.31 SEQ ID NO:2562 3063427 91.67

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SEQ ID NO:2590 3064667 92.86 SEQ ID NO:2638 3069556 92.86

SEQ ID NO:2591 3064818 92.86 SEQ ID NO:2639 3069565 92.86

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SEQ ID NO:2595 3065103 92.31 SEQ ID NO:2643 3069787 100.00

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SEQ ID NO:2600 3065290 92.86 SEQ ID NO:2648 3070037 92.86

SEQ ID NO:2601 3065377 92.86 SEQ ID NO:2649 3070068 92.86

SEQ ID NO:2602 3065408 92.86 SEQ ID NO:2650 3070126 92.86

SEQ ID NO:2603 3065597 83.33 SEQ ID NO:2651 3070284 92.86

SEQ ID NO:2604 3065630 100.00 SEQ ID NO:2652 3070290 92.31

SEQ ID NO:2605 3065647 100.00 SEQ ID NO:2653 3070312 76.92

SEQ ID NO:2606 3065658 100.00 SEQ ID NO:2654 3070358 92.86

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SEQ ID NO:2608 3065842 75.00 SEQ ID NO:2656 3070481 92.86

SEQ ID NO:2609 3065989 75.00 SEQ ID NO:2657 3070482 100.00

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SEQ ID NO:2612 3066212 92.86 SEQ ID NO:2660 3070663 100.00

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SEQ ID NO:2614 3066483 100.00 SEQ ID NO:2662 3070752 92.31

SEQ ID NO:2615 3066621 100.00 SEQ ID NO:2663 3070763 76.92

SEQ ID NO:2616 3066668 92.31 SEQ ID NO:2664 3070826 92.86

SEQ ID NO:2617 3066913 78.57 SEQ ID NO:2665 3070969 100.00

SEQ ID NO:2618 3066982 86.67 SEQ ID NO:2666 3070988 92.86

SEQ ID NO:2619 3067249 100.00 SEQ ID NO:2667 3070997 78.57

SEQ ID NO:2620 3068234 100.00 SEQ ID NO:2668 3071046 92.86

SEQ ID NO:2621 3068282 90.91 SEQ ID NO:2669 3071080 100.00

SEQ ID NO:2622 3068292 76.92 SEQ ID NO:2670 3071084 91.67

SEQ ID NO:2623 3068365 92.86 SEQ ID NO:2671 3071100 92.86

SEQ ID NO:2624 3068387 92.86 SEQ ID NO:2672 3071113 85.71

SEQ ID NO:2625 3068484 100.00 SEQ ID NO:2673 3071181 100.00

SEQ ID NO:2626 3068509 90.91 SEQ ID NO:2674 3071205 84.62

SEQ ID NO:2627 3068572 100.00 SEQ ID NO:2675 3071256 100.00

SEQ ID NO:2628 3068583 85.71 SEQ ID NO:2676 3071304 92.86

SEQ ID NO:2629 3068745 92.86 SEQ ID NO:2677 3071360 92.86

SEQ ID NO:2630 3068903 92.86 SEQ ID NO:2678 3071441 92.86 SEQ ID NO:2679 3071456 92.86 SEQ ID NO:2727 3110483 100.00

SEQ ID NO:2680 3071503 92.86 SEQ ID NO:2728 3111103 100.00

SEQ ID NO:2681 3071611 92.86 SEQ ID NO:2729 3111166 100.00

SEQ ID NO:2682 3071650 92.31 SEQ ID NO:2730 3111457 84.62

SEQ ID NO:2683 3071774 92.86 SEQ ID NO:2731 3111621 100.00

SEQ ID NO:2684 3072721 100.00 SEQ ID NO:2732 3112064 100.00

SEQ ID NO:2685 3073476 92.86 SEQ ID NO:2733 3112129 84.62

SEQ ID NO:2686 3073507 92.31 SEQ ID NO:2734 3114911 100.00

SEQ ID NO:2687 3073560 100.00 SEQ ID NO:2735 3123165 93.33

SEQ ID NO:2688 3073561 88.89 SEQ ID NO:2736 3129294 84.62

SEQ ID NO:2689 3073698 100.00 SEQ ID NO:2737 3129414 100.00

SEQ ID NO:2690 3073720 100.00 SEQ ID NO:2738 3129920 100.00

SEQ ID NO:2691 3073744 92.31 SEQ ID NO:2739 3134329 100.00

SEQ ID NO:2692 3073755 90.91 SEQ ID NO:2740 3135317 100.00

SEQ ID NO:2693 3073778 92.86 SEQ ID NO:2741 3135413 100.00

SEQ ID NO:2694 3073793 100.00 SEQ ID NO:2742 3135680 100.00

SEQ ID NO:2695 3073869 100.00 SEQ ID NO:2743 3135789 100.00

SEQ ID NO:2696 3073893 100.00 SEQ ID NO:2744 3136368 100.00

SEQ ID NO:2697 3073903 100.00 SEQ ID NO:2745 3141656 100.00

SEQ ID NO:2698 3073955 100.00 SEQ ID NO:2746 3141849 92.31

SEQ ID NO:2699 3073970 100.00 SEQ ID NO:2747 3142769 100.00

SEQ ID NO:2700 3073976 100.00 SEQ ID NO:2748 3142793 100.00

SEQ ID NO:2701 3074041 100.00 SEQ ID NO:2749 3143267 100.00

SEQ ID NO:2702 3074101 100.00 SEQ ID NO:2750 3143801 100.00

SEQ ID NO:2703 3074157 100.00 SEQ ID NO:2751 3143853 100.00

SEQ ID NO:2704 3074198 100.00 SEQ ID NO:2752 3144125 100.00

SEQ ID NO:2705 3074258 100.00 SEQ ID NO:2753 3144152 100.00

SEQ ID NO:2706 3074409 100.00 SEQ ID NO:2754 3144873 100.00

SEQ ID NO:2707 3074515 100.00 SEQ ID NO:2755 3146581 100.00

SEQ ID NO:2708 3074694 83.33 SEQ ID NO:2756 3146941 100.00

SEQ ID NO:2709 3074877 75.00 SEQ ID NO:2757 3147413 100.00

SEQ ID NO:2710 3075406 92.86 SEQ ID NO:2758 3148887 100.00

SEQ ID NO:2711 3075940 100.00 SEQ ID NO:2759 3148928 100.00

SEQ ID NO:2712 3076221 92.86 SEQ ID NO:2760 3149643 85.71

SEQ ID NO:2713 3076297 100.00 SEQ ID NO:2761 3150263 100.00

SEQ ID NO:2714 3076314 92.86 SEQ ID NO:2762 3150597 100.00

SEQ ID NO:2715 3078265 100.00 SEQ ID NO:2763 3150782 75.00

SEQ ID NO:2716 3078754 93.33 SEQ ID NO:2764 3150797 75.00

SEQ ID NO:2717 3079191 100.00 SEQ ID NO:2765 3150957 100.00

SEQ ID NO:2718 3079272 90.91 SEQ ID NO:2766 3151073 100.00

SEQ ID NO:2719 3079744 100.00 SEQ ID NO:2767 3151353 100.00

SEQ ID NO:2720 3082298 100.00 SEQ ID NO:2768 3152351 100.00

SEQ ID NO:2721 3087429 100.00 SEQ ID NO:2769 3152476 100.00

SEQ ID NO:2722 3087658 100.00 SEQ ID NO:2770 3152512 100.00

SEQ ID NO:2723 3103297 100.00 SEQ ID NO:2771 3153883 100.00

SEQ ID NO:2724 3109695 83.33 SEQ ID NO:2772 3155056 92.31

SEQ ID NO:2725 3109980 100.00 SEQ ID NO:2773 3155078 86.67

SEQ ID NO:2726 3110087 100.00 SEQ ID NO:2774 3155103 92.86 SEQ ID NO:2775 3155217 92.86 SEQ ID NO:2823 3177499 100.00

SEQ ID NO:2776 3156383 83.33 SEQ ID NO:2824 3178326 93.33

SEQ ID NO:2777 3156442 100.00 SEQ ID NO:2825 3178391 93.33

SEQ ID NO:2778 3157049 93.33 SEQ ID NO:2826 3179860 100.00

SEQ ID NO:2779 3157421 88.89 SEQ ID NO:2827 3180190 100.00

SEQ ID NO:2780 3157479 92.86 SEQ ID NO:2828 3180675 100.00

SEQ ID NO:2781 3157650 92.86 SEQ ID NO:2829 3181043 100.00

SEQ ID NO:2782 3158080 86.67 SEQ ID NO:2830 3181212 90.91

SEQ ID NO:2783 3158259 100.00 SEQ ID NO:2831 3181351 100.00

SEQ ID NO:2784 3158305 100.00 SEQ ID NO:2832 3181573 100.00

SEQ ID NO:2785 3158359 100.00 SEQ ID NO:2833 3181578 100.00

SEQ ID NO:2786 3158557 92.86 SEQ ID NO:2834 3181645 100.00

SEQ ID NO:2787 3158711 72.73 SEQ ID NO:2835 3187460 100.00

SEQ ID NO:2788 3159026 100.00 SEQ ID NO:2836 3191381 100.00

SEQ ID NO:2789 3159144 92.31 SEQ ID NO:2837 3191800 100.00

SEQ ID NO:2790 3159667 91.67 SEQ ID NO:2838 3192957 100.00

SEQ ID NO:2791 3159823 100.00 SEQ ID NO:2839 3195272 100.00

SEQ ID NO:2792 3159866 100.00 SEQ ID NO:2840 3195722 90.91

SEQ ID NO:2793 3159884 100.00 SEQ ID NO:2841 3195762 100.00

SEQ ID NO:2794 3160197 92.31 SEQ ID NO:2842 3195809 100.00

SEQ ID NO:2795 3160213 100.00 SEQ ID NO:2843 3195957 100.00

SEQ ID NO:2796 3160379 75.00 SEQ ID NO:2844 3196018 93.33

SEQ ID NO:2797 3160753 100.00 SEQ ID NO:2845 3196332 100.00

SEQ ID NO:2798 3160946 92.86 SEQ ID NO:2846 3196388 100.00

SEQ ID NO:2799 3161356 76.92 SEQ ID NO:2847 3196513 100.00

SEQ ID NO:2800 3161825 92.86 SEQ ID NO:2848 3196647 100.00

SEQ ID NO:2801 3161907 100.00 SEQ ID NO:2849 3198675 100.00

SEQ ID NO:2802 3162294 92.86 SEQ ID NO:2850 3200140 100.00

SEQ ID NO:2803 3162422 100.00 SEQ ID NO:2851 3202899 80.00

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SEQ ID NO:3202 3454060 100.00 SEQ ID NO:3250 3505544 92.86

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SEQ ID NO:3204 3454157 100.00 SEQ ID NO:3252 3506199 91.67

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SEQ ID NO:3256 3506530 85.71 SEQ ID NO:3304 3516912 100.00

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SEQ ID NO:3262 3508250 77.78 SEQ ID NO:3310 3517798 92.86

SEQ ID NO:3263 3508279 100.00 SEQ ID NO:3311 3518208 100.00

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SEQ ID NO:3278 3511080 84.62 SEQ ID NO:3326 3519003 90.91

SEQ ID NO:3279 3511594 100.00 SEQ ID NO:3327 3519047 100.00

SEQ ID NO:3280 3511988 92.86 SEQ ID NO:3328 3519107 100.00

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SEQ ID NO:3282 3512454 100.00 SEQ ID NO:3330 3519170 92.86

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SEQ ID NO:3286 3513535 92.86 SEQ ID NO:3334 3520522 100.00

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SEQ ID NO:3289 3514712 100.00 SEQ ID NO:3337 3521130 88.89

SEQ ID NO:3290 3515097 100.00 SEQ ID NO:3338 3521186 92.31

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SEQ ID NO:3293 3515417 92.86 SEQ ID NO:3341 3521427 92.31

SEQ ID NO:3294 3515420 92.86 SEQ ID NO:3342 3521534 100.00

SEQ ID NO:3295 3515435 93.33 SEQ ID NO:3343 3521592 83.33

SEQ ID NO:3296 3515443 100.00 SEQ ID NO:3344 3521748 100.00

SEQ ID NO:3297 3515494 92.86 SEQ ID NO:3345 3522077 92.86

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SEQ ID NO:3299 3515817 92.31 SEQ ID NO:3347 3522274 92.31

SEQ ID NO:3300 3515856 92.86 SEQ ID NO:3348 3522334 92.86

SEQ ID NO:3301 3516080 86.67 SEQ ID NO:3349 3522399 92.86

SEQ ID NO:3302 3516281 100.00 SEQ ID NO:3350 3522417 92.86 SEQ ID NO:3351 3522628 92.86 SEQ ID NO:3399 3529077 92.86

SEQ ID NO:3352 3522938 92.86 SEQ ID NO:3400 3529147 90.00

SEQ ID NO:3353 3523116 93.33 SEQ ID NO:3401 3529209 92.86

SEQ ID NO:3354 3523138 92.31 SEQ ID NO:3402 3529250 92.86

SEQ ID NO:3355 3523465 92.86 SEQ ID NO:3403 3529253 92.86

SEQ ID NO:3356 3523721 91.67 SEQ ID NO:3404 3529371 93.33

SEQ ID NO:3357 3523865 86.67 SEQ ID NO:3405 3529380 92.86

SEQ ID NO:3358 3523876 91.67 SEQ ID NO:3406 3529410 92.86

SEQ ID NO:3359 3524136 86.67 SEQ ID NO:3407 3529427 93.33

SEQ ID NO:3360 3524338 92.86 SEQ ID NO:3408 3529441 92.86

SEQ ID NO:3361 3524382 93.33 SEQ ID NO:3409 3529483 92.86

SEQ ID NO:3362 3524606 92.86 SEQ ID NO:3410 3529514 92.86

SEQ ID NO:3363 3524634 90.91 SEQ ID NO:3411 3529566 92.31

SEQ ID NO:3364 3524650 90.00 SEQ ID NO:3412 3529582 70.00

SEQ ID NO:3365 3524663 90.91 SEQ ID NO:3413 3529611 90.00

SEQ ID NO:3366 3524691 92.31 SEQ ID NO:3414 3529664 92.86

SEQ ID NO:3367 3525337 91.67 SEQ ID NO:3415 3529878 92.86

SEQ ID NO:3368 3525360 92.86 SEQ ID NO:3416 3529975 93.33

SEQ ID NO:3369 3525454 75.00 SEQ ID NO:3417 3530317 92.31

SEQ ID NO:3370 3525735 92.86 SEQ ID NO:3418 3530431 92.86

SEQ ID NO:3371 3525804 92.86 SEQ ID NO:3419 3530678 90.91

SEQ ID NO:3372 3525886 92.86 SEQ ID NO:3420 3530696 92.86

SEQ ID NO:3373 3525898 92.86 SEQ ID NO:3421 3530844 90.00

SEQ ID NO:3374 3525906 92.86 SEQ ID NO:3422 3531109 91.67

SEQ ID NO:3375 3525928 86.67 SEQ ID NO:3423 3531215 92.86

SEQ ID NO:3376 3525939 92.86 SEQ ID NO:3424 3531233 92.31

SEQ ID NO:3377 3525945 92.86 SEQ ID NO:3425 3531245 92.31

SEQ ID NO:3378 3525968 92.86 SEQ ID NO:3426 3531257 92.86

SEQ ID NO:3379 3526020 70.00 SEQ ID NO:3427 3531277 92.31

SEQ ID NO:3380 3526050 85.71 SEQ ID NO:3428 3531291 91.67

SEQ ID NO:3381 3526083 81.82 SEQ ID NO:3429 3531327 92.31

SEQ ID NO:3382 3526193 72.73 SEQ ID NO:3430 3531329 85.71

SEQ ID NO:3383 3526295 90.91 SEQ ID NO:3431 3531493 100.00

SEQ ID NO:3384 3526405 83.33 SEQ ID NO:3432 3531531 91.67

SEQ ID NO:3385 3526426 100.00 SEQ ID NO:3433 3531533 90.00

SEQ ID NO:3386 3526444 92.31 SEQ ID NO:3434 3531546 92.31

SEQ ID NO:3387 3526925 92.86 SEQ ID NO:3435 3531557 92.86

SEQ ID NO:3388 3526936 76.92 SEQ ID NO:3436 3531572 100.00

SEQ ID NO:3389 3526955 93.33 SEQ ID NO:3437 3531588 92.86

SEQ ID NO:3390 3527209 92.86 SEQ ID NO:3438 3531609 92.86

SEQ ID NO:3391 3527492 92.86 SEQ ID NO:3439 3531659 87.50

SEQ ID NO:3392 3527769 92.86 SEQ ID NO:3440 3531679 100.00

SEQ ID NO:3393 3527910 92.86 SEQ ID NO:3441 3531731 92.31

SEQ ID NO:3394 3527979 93.33 SEQ ID NO:3442 3531767 92.31

SEQ ID NO:3395 3527995 93.33 SEQ ID NO:3443 3531784 92.86

SEQ ID NO:3396 3528092 92.86 SEQ ID NO:3444 3531808 87.50

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SEQ ID NO:3471 3532751 91.67 SEQ ID NO:3519 3536401 91.67

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SEQ ID NO:3766 3846740 78.57 SEQ ID NO:3814 3868554 75.00

SEQ ID NO:3767 3846821 93.33 SEQ ID NO:3815 3869809 80.00

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SEQ ID NO:3770 3847013 75.00 SEQ ID NO:3818 3871763 85.71

SEQ ID NO:3771 3847240 93.33 SEQ ID NO:3819 3872280 80.00

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SEQ ID NO:3782 3865679 92.86 SEQ ID NO:3830 3893738 88.89 SEQ ID NO:3831 3908192 83.33 SEQ ID NO:3879 3946661 92.86

SEQ ID NO:3832 3909620 92.86 SEQ ID NO:3880 3947406 92.86

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SEQ ID NO:3844 3915504 85.71 SEQ ID NO:3892 3952724 75.00

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SEQ ID NO:3846 3918408 92.86 SEQ ID NO:3894 3953040 92.86

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SEQ ID NO:3848 3919050 87.50 SEQ ID NO:3896 3953106 80.00

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SEQ ID NO:3851 3919115 92.31 SEQ ID NO:3899 3954335 93.33

SEQ ID NO:3852 3921038 85.71 SEQ ID NO:3900 3954354 92.86

SEQ ID NO:3853 3921109 75.00 SEQ ID NO:3901 3954399 100.00

SEQ ID NO:3854 3921114 75.00 SEQ ID NO:3902 3954434 80.00

SEQ ID NO:3855 3921498 87.50 SEQ ID NO:3903 3954775 90.00

SEQ ID NO:3856 3921550 85.71 SEQ ID NO:3904 3955227 75.00

SEQ ID NO:3857 3921581 75.00 SEQ ID NO:3905 3955822 93.33

SEQ ID NO:3858 3921617 75.00 SEQ ID NO:3906 3955849 93.33

SEQ ID NO:3859 3921766 75.00 SEQ ID NO:3907 3955889 93.33

SEQ ID NO:3860 3921778 92.86 SEQ ID NO:3908 3955940 92.86

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SEQ ID NO:3864 3923520 83.33 SEQ ID NO:3912 3956557 92.86

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SEQ ID NO:3866 3926165 100.00 SEQ ID NO:3914 3956650 92.86

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SEQ ID NO:3868 3932362 75.00 SEQ ID NO:3916 3964062 100.00

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SEQ ID NO:3878 3946404 75.00 SEQ ID NO:3926 3968107 100.00 SEQ ID NO:3927 3968527 100.00 SEQ ID NO:3975 3979025 100.00

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SEQ ID NO:3952 3975791 100.00 SEQ ID NO:4000 3996691 100.00

SEQ ID NO:3953 3975926 93.33 SEQ ID NO:4001 3996788 80.00

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SEQ ID NO:3958 3976277 81.82 SEQ ID NO:4006 4007572 100.00

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SEQ ID NO:3961 3976614 100.00 SEQ ID NO:4009 4007978 75.00

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SEQ ID NO:3970 3978305 84.62 SEQ ID NO:4018 4009127 100.00

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SEQ ID NO:3972 3978908 93.33 SEQ ID NO:4020 4009544 100.00

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SEQ ID NO:3974 3978991 93.33 SEQ ID NO:4022 4009711 88.89 SEQ ID NO:4023 4009719 100.00 SEQ ID NO:4071 4050956 100.00

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SEQ ID NO:4031 4010475 100.00 SEQ ID NO:4079 4057692 75.00

SEQ ID NO:4032 4010528 100.00 SEQ ID NO:4080 4058562 92.31

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SEQ ID NO:4319 4192226 100.00 SEQ ID NO:4367 4313083 92.86

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SEQ ID NO:4428 4455677 87.50 SEQ ID NO:4476 4561321 87.50

SEQ ID NO:4429 4455784 92.86 SEQ ID NO:4477 4561348 80.00

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SEQ ID NO:4431 4455898 91.67 SEQ ID NO:4479 4561625 87.50

SEQ ID NO:4432 4467315 100.00 SEQ ID NO:4480 4561635 100.00

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SEQ ID NO:4444 4492146 100.00 SEQ ID NO:4492 4572041 90.00

SEQ ID NO:4445 4516053 92.31 SEQ ID NO:4493 4572072 100.00

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SEQ ID NO:4447 4523088 100.00 SEQ ID NO:4495 4573498 91.67

SEQ ID NO:4448 4529983 87.50 SEQ ID NO:4496 4574182 100.00

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SEQ ID NO:4454 4530623 92.86 SEQ ID NO:4502 4575938 85.71 SEQ ID NO:4503 4575964 87.50 SEQ ID NO:4551 4584200 80.00

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SEQ ID NO:4505 4576067 92.31 SEQ ID NO:4553 4584232 100.00

SEQ ID NO:4506 4576116 92.86 SEQ ID NO:4554 4584714 92.86

SEQ ID NO:4507 4576127 92.86 SEQ ID NO:4555 4584815 100.00

SEQ ID NO:4508 4576200 92.86 SEQ ID NO:4556 4584848 91.67

SEQ ID NO:4509 4576223 90.91 SEQ ID NO:4557 4584884 92.86

SEQ ID NO:4510 4576343 92.31 SEQ ID NO:4558 4585108 75.00

SEQ ID NO:4511 4576379 90.00 SEQ ID NO:4559 4585131 91.67

SEQ ID NO:4512 4576811 100.00 SEQ ID NO:4560 4585547 100.00

SEQ ID NO:4513 4578418 85.71 SEQ ID NO:4561 4586250 88.89

SEQ ID NO:4514 4578980 92.31 SEQ ID NO:4562 4586596 92.86

SEQ ID NO:4515 4579048 92.31 SEQ ID NO:4563 4587026 85.71

SEQ ID NO:4516 4579096 91.67 SEQ ID NO:4564 4587233 92.86

SEQ ID NO:4517 4579132 90.91 SEQ ID NO:4565 4588894 91.67

SEQ ID NO:4518 4579897 80.00 SEQ ID NO:4566 4589000 92.86

SEQ ID NO:4519 4579908 100.00 SEQ ID NO:4567 4589682 100.00

SEQ ID NO:4520 4579992 100.00 SEQ ID NO:4568 4590008 100.00

SEQ ID NO:4521 4580054 75.00 SEQ ID NO:4569 4590091 100.00

SEQ ID NO:4522 4581027 91.67 SEQ ID NO:4570 4590113 100.00

SEQ ID NO:4523 4581060 90.00 SEQ ID NO:4571 4590225 100.00

SEQ ID NO:4524 4581094 92.86 SEQ ID NO:4572 4590360 100.00

SEQ ID NO:4525 4581107 92.31 SEQ ID NO:4573 4590464 100.00

SEQ ID NO:4526 4581112 92.86 SEQ ID NO:4574 4590470 100.00

SEQ ID NO:4527 4581238 92.86 SEQ ID NO:4575 4590481 84.62

SEQ ID NO:4528 4581251 92.86 SEQ ID NO:4576 4590612 93.33

SEQ ID NO:4529 4581256 92.86 SEQ ID NO:4577 4590678 100.00

SEQ ID NO:4530 4581434 92.86 SEQ ID NO:4578 4590722 100.00

SEQ ID NO:4531 4581463 92.86 SEQ ID NO:4579 4590816 86.67

SEQ ID NO:4532 4581523 88.89 SEQ ID NO:4580 4590981 100.00

SEQ ID NO:4533 4581547 100.00 SEQ ID NO:4581 4591010 100.00

SEQ ID NO:4534 4581984 92.86 SEQ ID NO:4582 4591017 100.00

SEQ ID NO:4535 4582058 92.31 SEQ ID NO:4583 4591070 71.43

SEQ ID NO:4536 4582352 92.86 SEQ ID NO:4584 4591178 100.00

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SEQ ID NO:4538 4582501 92.86 SEQ ID NO:4586 4591399 100.00

SEQ ID NO:4539 4582583 92.31 SEQ ID NO:4587 4591466 100.00

SEQ ID NO:4540 4582845 92.86 SEQ ID NO:4588 4591491 93.33

SEQ ID NO:4541 4583084 92.86 SEQ ID NO:4589 4591895 100.00

SEQ ID NO:4542 4583195 92.31 SEQ ID NO:4590 4591929 92.86

SEQ ID NO:4543 4583488 92.86 SEQ ID NO:4591 4591941 100.00

SEQ ID NO:4544 4583678 92.86 SEQ ID NO:4592 4592016 100.00

SEQ ID NO:4545 4584087 88.89 SEQ ID NO:4593 4593806 93.33

SEQ ID NO:4546 4584105 90.91 SEQ ID NO:4594 4593968 92.86

SEQ ID NO:4547 4584114 90.00 SEQ ID NO:4595 4594224 100.00

SEQ ID NO:4548 4584117 88.89 SEQ ID NO:4596 4595188 80.00

SEQ ID NO:4549 4584190 80.00 SEQ ID NO:4597 4595262 100.00

SEQ ID NO:4550 4584196 80.00 SEQ ID NO:4598 4597454 100.00 SEQ ID NO:4599 4597575 100.00 SEQ ID NO:4647 4642146 100.00

SEQ ID NO:4600 4597731 100.00 SEQ ID NO:4648 4642454 90.00

SEQ ID NO:4601 4598150 100.00 SEQ ID NO:4649 4646187 93.33

SEQ ID NO:4602 4599521 100.00 SEQ ID NO:4650 4646372 93.33

SEQ ID NO:4603 4600036 100.00 SEQ ID NO:4651 4654023 93.33

SEQ ID NO:4604 4609262 100.00 SEQ ID NO:4652 4654481 92.86

SEQ ID NO:4605 4609307 92.86 SEQ ID NO:4653 4654692 92.86

SEQ ID NO:4606 4609346 93.33 SEQ ID NO:4654 4654734 100.00

SEQ ID NO:4607 4609501 100.00 SEQ ID NO:4655 4655580 100.00

SEQ ID NO:4608 4610032 100.00 SEQ ID NO:4656 4655702 100.00

SEQ ID NO:4609 4610535 93.33 SEQ ID NO:4657 4655997 100.00

SEQ ID NO:4610 4612069 100.00 SEQ ID NO:4658 4656290 100.00

SEQ ID NO:4611 4612327 100.00 SEQ ID NO:4659 4656319 100.00

SEQ ID NO:4612 4615137 100.00 SEQ ID NO:4660 4656898 100.00

SEQ ID NO:4613 4615738 100.00 SEQ ID NO:4661 4657261 100.00

SEQ ID NO:4614 4622463 100.00 SEQ ID NO:4662 4657503 100.00

SEQ ID NO:4615 4623039 100.00 SEQ ID NO:4663 4657907 100.00

SEQ ID NO:4616 4623048 86.67 SEQ ID NO:4664 4658574 100.00

SEQ ID NO:4617 4624101 75.00 SEQ ID NO:4665 4659302 100.00

SEQ ID NO:4618 4624450 75.00 SEQ ID NO:4666 4659317 100.00

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SEQ ID NO:5094 4797338 70.00 SEQ ID NO:5142 4816159 93.33

SEQ ID NO:5095 4797482 100.00 SEQ ID NO:5143 4816204 93.33

SEQ ID NO:5096 4798799 92.86 SEQ ID NO:5144 4816274 93.33

SEQ ID NO:5097 4799309 100.00 SEQ ID NO:5145 4816747 100.00

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SEQ ID NO:5110 4805925 90.00 SEQ ID NO:5158 4818957 100.00

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SEQ ID NO:5112 4806090 92.86 SEQ ID NO:5160 4820018 100.00

SEQ ID NO:5113 4806195 92.86 SEQ ID NO:5161 4820025 100.00

SEQ ID NO:5114 4806285 92.31 SEQ ID NO:5162 4820031 100.00

SEQ ID NO:5115 4806321 90.91 SEQ ID NO:5163 4820336 85.71

SEQ ID NO:5116 4806573 92.31 SEQ ID NO:5164 4820384 83.33

SEQ ID NO:5117 4806584 85.71 SEQ ID NO:5165 4824861 83.33

SEQ ID NO:5118 4806602 92.86 SEQ ID NO:5166 4824998 86.67

SEQ ID NO:5119 4806625 93.33 SEQ ID NO:5167 4825013 90.91

SEQ ID NO:5120 4806846 88.89 SEQ ID NO:5168 4825466 92.86

SEQ ID NO:5121 4807016 75.00 SEQ ID NO:5169 4825844 91.67

SEQ ID NO:5122 4807529 92.86 SEQ ID NO:5170 4828414 90.00

SEQ ID NO:5123 4807685 83.33 SEQ ID NO:5171 4829738 100.00

SEQ ID NO:5124 4808056 91.67 SEQ ID NO:5172 4830525 100.00

SEQ ID NO:5125 4808250 91.67 SEQ ID NO:5173 4831394 100.00

SEQ ID NO:5126 4808261 90.91 SEQ ID NO:5174 4831415 92.86 SEQ ID NO:5175 4832121 100.00 SEQ ID NO:5223 4858598 72.73

SEQ ID NO:5176 4835418 100.00 SEQ ID NO:5224 4858640 81.82

SEQ ID NO:5177 4835621 100.00 SEQ ID NO:5225 4858720 100.00

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SEQ ID NO:5179 4836492 100.00 SEQ ID NO:5227 4858899 92.86

SEQ ID NO:5180 4836514 100.00 SEQ ID NO:5228 4858941 83.33

SEQ ID NO:5181 4840732 100.00 SEQ ID NO:5229 4858972 92.86

SEQ ID NO:5182 4841024 100.00 SEQ ID NO:5230 4858978 92.31

SEQ ID NO:5183 4841954 100.00 SEQ ID NO:5231 4859005 92.86

SEQ ID NO:5184 4842516 100.00 SEQ ID NO:5232 4859526 100.00

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SEQ ID NO:5187 4844578 100.00 SEQ ID NO:5235 4860692 92.86

SEQ ID NO:5188 4849812 91.67 SEQ ID NO:5236 4860719 100.00

SEQ ID NO:5189 4851181 92.86 SEQ ID NO:5237 4860769 100.00

SEQ ID NO:5190 4851188 92.86 SEQ ID NO:5238 4861658 100.00

SEQ ID NO:5191 4851209 92.86 SEQ ID NO:5239 4861664 100.00

SEQ ID NO:5192 4851272 100.00 SEQ ID NO:5240 4866450 92.86

SEQ ID NO:5193 4851316 92.86 SEQ ID NO:5241 4866794 88.89

SEQ ID NO:5194 4851691 100.00 SEQ ID NO:5242 4866814 92.31

SEQ ID NO:5195 4852080 100.00 SEQ ID NO:5243 4866895 90.91

SEQ ID NO:5196 4852779 86.67 SEQ ID NO:5244 4866979 92.86

SEQ ID NO:5197 4853050 92.86 SEQ ID NO:5245 4866991 91.67

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SEQ ID NO:5200 4854873 100.00 SEQ ID NO:5248 4867126 92.31

SEQ ID NO:5201 4855323 80.00 SEQ ID NO:5249 4867146 78.57

SEQ ID NO:5202 4856290 100.00 SEQ ID NO:5250 4867157 90.00

SEQ ID NO:5203 4856449 100.00 SEQ ID NO:5251 4867592 86.67

SEQ ID NO:5204 4856685 93.33 SEQ ID NO:5252 4867670 92.31

SEQ ID NO:5205 4856780 100.00 SEQ ID NO:5253 4868066 92.86

SEQ ID NO:5206 4856912 100.00 SEQ ID NO:5254 4868979 92.86

SEQ ID NO:5207 4857360 93.33 SEQ ID NO:5255 4869054 93.33

SEQ ID NO:5208 4857442 92.86 SEQ ID NO:5256 4869307 100.00

SEQ ID NO:5209 4857451 92.31 SEQ ID NO:5257 4869938 92.86

SEQ ID NO:5210 4857464 90.91 SEQ ID NO:5258 4870266 92.86

SEQ ID NO:5211 4857678 100.00 SEQ ID NO:5259 4871172 100.00

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SEQ ID NO:5215 4857823 70.00 SEQ ID NO:5263 4872349 86.67

SEQ ID NO:5216 4857872 92.86 SEQ ID NO:5264 4873610 93.33

SEQ ID NO:5217 4857946 75.00 SEQ ID NO:5265 4873952 75.00

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SEQ ID NO:5596 5030458 92.31 SEQ ID NO:5644 5076956 100.00

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SEQ ID NO:5662 5086218 86.67 SEQ ID NO:5710 5104617 92.86

SEQ ID NO:5663 5086971 92.31 SEQ ID NO:5711 5104677 100.00

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SEQ ID NO:5682 5093805 100.00 SEQ ID NO:5730 5124417 85.71

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SEQ ID NO:5686 5094459 100.00 SEQ ID NO:5734 5132015 92.86

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SEQ ID NO:5767 5152271 100.00 SEQ ID NO:5815 5194972 93.33

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SEQ ID NO:5769 5162329 100.00 SEQ ID NO:5817 5195491 92.31

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SEQ ID NO:6441 5509198 93.33 SEQ ID NO:6489 5511636 100.00

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SEQ ID NO:6447 5509332 92.31 SEQ ID NO:6495 5513419 93.33

SEQ ID NO:6448 5509391 88.89 SEQ ID NO:6496 5514044 100.00

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SEQ ID NO:6460 5509907 81.82 SEQ ID NO:6508 5517447 100.00

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SEQ ID NO:6462 5510194 100.00 SEQ ID NO:6510 5517806 93.33

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SEQ ID NO:6464 5510746 100.00 SEQ ID NO:6512 5518250 100.00

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SEQ ID NO:6466 5510852 91.67 SEQ ID NO:6514 5519354 93.33

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SEQ ID NO:6468 5510922 87.50 SEQ ID NO:6516 5519493 100.00

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SEQ ID NO:6522 5521126 92.31 SEQ ID NO:6570 5578337 100.00

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SEQ ID NO:6553 5552521 100.00 SEQ ID NO:6601 5590297 86.67

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SEQ ID NO:6566 5575330 92.86 SEQ ID NO:6614 5599052 92.86 SEQ ID NO:6615 5600746 92.86 SEQ ID NO:6663 5639527 100.00

SEQ ID NO:6616 5601287 88.89 SEQ ID NO:6664 5640635 100.00

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SEQ ID NO:6622 5604592 91.67 SEQ ID NO:6670 5643641 93.33

SEQ ID NO:6623 5604992 100.00 SEQ ID NO:6671 5643905 92.86

SEQ ID NO:6624 5605161 92.31 SEQ ID NO:6672 5644442 92.86

SEQ ID NO:6625 5605580 100.00 SEQ ID NO:6673 5645533 100.00

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SEQ ID NO:6627 5607674 92.31 SEQ ID NO:6675 5645981 100.00

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SEQ ID NO:6638 5618220 92.86 SEQ ID NO:6686 5647283 100.00

SEQ ID NO:6639 5619159 93.33 SEQ ID NO:6687 5647486 100.00

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SEQ ID NO:6641 5620817 100.00 SEQ ID NO:6689 5647620 100.00

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SEQ ID NO:6644 5621200 90.91 SEQ ID NO:6692 5647733 100.00

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SEQ ID NO:6662 5638736 92.86 SEQ ID NO:6710 5657399 100.00 SEQ ID NO:6711 5657409 100.00 SEQ ID NO:6759 5660958 100.00

SEQ ID NO:6712 5657432 80.00 SEQ ID NO:6760 5661163 100.00

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SEQ ID NO:6758 5660934 100.00 SEQ ID NO:6806 5667857 100.00 SEQ ID NO:6807 5667861 83.33 SEQ ID NO:6855 5727301 85.71

SEQ ID NO:6808 5667932 83.33 SEQ ID NO:6856 5727327 75.00

SEQ ID NO:6809 5668738 100.00 SEQ ID NO:6857 5727498 75.00

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SEQ ID NO:6815 5670883 92.31 SEQ ID NO:6863 5728850 80.00

SEQ ID NO:6816 5671176 100.00 SEQ ID NO:6864 5728881 75.00

SEQ ID NO:6817 5671211 100.00 SEQ ID NO:6865 5728888 75.00

SEQ ID NO:6818 5671280 93.33 SEQ ID NO:6866 5729404 93.33

SEQ ID NO:6819 5671746 91.67 SEQ ID NO:6867 5730140 75.00

SEQ ID NO:6820 5671772 100.00 SEQ ID NO:6868 5731072 83.33

SEQ ID NO:6821 5671803 100.00 SEQ ID NO:6869 5731891 93.33

SEQ ID NO:6822 5672193 92.86 SEQ ID NO:6870 5733239 93.33

SEQ ID NO:6823 5672409 92.86 SEQ ID NO:6871 5733331 75.00

SEQ ID NO:6824 5672741 100.00 SEQ ID NO:6872 5734228 93.33

SEQ ID NO:6825 5672951 83.33 SEQ ID NO:6873 5734980 75.00

SEQ ID NO:6826 5673395 90.00 SEQ ID NO:6874 5736184 100.00

SEQ ID NO:6827 5673668 90.00 SEQ ID NO:6875 5736280 100.00

SEQ ID NO:6828 5673940 92.86 SEQ ID NO:6876 5736335 100.00

SEQ ID NO:6829 5674307 87.50 SEQ ID NO:6877 5736418 100.00

SEQ ID NO:6830 5674311 91.67 SEQ ID NO:6878 5736578 100.00

SEQ ID NO:6831 5676455 92.31 SEQ ID NO:6879 5736667 100.00

SEQ ID NO:6832 5676560 90.00 SEQ ID NO:6880 5737623 100.00

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SEQ ID NO:6839 5688027 83.33 SEQ ID NO:6887 5739026 93.33

SEQ ID NO:6840 5691802 92.86 SEQ ID NO:6888 5739146 100.00

SEQ ID NO:6841 5708344 90.91 SEQ ID NO:6889 5739774 92.86

SEQ ID NO:6842 5710199 80.00 SEQ ID NO:6890 5739809 100.00

SEQ ID NO:6843 5710201 75.00 SEQ ID NO:6891 5739816 100.00

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SEQ ID NO:6845 5713316 100.00 SEQ ID NO:6893 5740028 92.31

SEQ ID NO:6846 5721671 85.71 SEQ ID NO:6894 5740085 92.86

SEQ ID NO:6847 5722893 100.00 SEQ ID NO:6895 5740122 92.86

SEQ ID NO:6848 5725738 75.00 SEQ ID NO:6896 5740513 92.86

SEQ ID NO:6849 5726428 90.00 SEQ ID NO:6897 5740991 100.00

SEQ ID NO:6850 5727003 93.33 SEQ ID NO:6898 5741194 100.00

SEQ ID NO:6851 5727044 83.33 SEQ ID NO:6899 5742244 92.86

SEQ ID NO:6852 5727064 93.33 SEQ ID NO:6900 5743240 93.33

SEQ ID NO:6853 5727210 85.71 SEQ ID NO:6901 5743295 93.33

SEQ ID NO:6854 5727216 75.00 SEQ ID NO:6902 5743395 78.57 SEQ ID NO:6903 5743567 93.33 SEQ ID NO:6951 5783887 100.00

SEQ ID NO:6904 5743954 100.00 SEQ ID NO:6952 5783921 100.00

SEQ ID NO:6905 5744031 93.33 SEQ ID NO:6953 5785604 100.00

SEQ ID NO:6906 5744150 100.00 SEQ ID NO:6954 5786424 100.00

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SEQ ID NO:6911 5745452 100.00 SEQ ID NO:6959 5790924 92.86

SEQ ID NO:6912 5745601 100.00 SEQ ID NO:6960 5790936 92.86

SEQ ID NO:6913 5745732 100.00 SEQ ID NO:6961 5791796 90.00

SEQ ID NO:6914 5746082 100.00 SEQ ID NO:6962 5793096 92.86

SEQ ID NO:6915 5746120 100.00 SEQ ID NO:6963 5793175 92.86

SEQ ID NO:6916 5747152 100.00 SEQ ID NO:6964 5793295 92.31

SEQ ID NO:6917 5747227 100.00 SEQ ID NO:6965 5793309 90.91

SEQ ID NO:6918 5747270 100.00 SEQ ID NO:6966 5793415 100.00

SEQ ID NO:6919 5747304 100.00 SEQ ID NO:6967 5793425 80.00

SEQ ID NO:6920 5747427 100.00 SEQ ID NO:6968 5793530 75.00

SEQ ID NO:6921 5747817 100.00 SEQ ID NO:6969 5793665 75.00

SEQ ID NO:6922 5766352 100.00 SEQ ID NO:6970 5793764 85.71

SEQ ID NO:6923 5766523 80.00 SEQ ID NO:6971 5793939 91.67

SEQ ID NO:6924 5766541 80.00 SEQ ID NO:6972 5793956 92.86

SEQ ID NO:6925 5766880 100.00 SEQ ID NO:6973 5794112 92.31

SEQ ID NO:6926 5768316 80.00 SEQ ID NO:6974 5794156 100.00

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SEQ ID NO:6928 5768739 100.00 SEQ ID NO:6976 5794233 92.31

SEQ ID NO:6929 5768747 100.00 SEQ ID NO:6977 5794299 100.00

SEQ ID NO:6930 5768862 100.00 SEQ ID NO:6978 5794309 83.33

SEQ ID NO:6931 5768923 100.00 SEQ ID NO:6979 5794316 80.00

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SEQ ID NO:6933 5770823 100.00 SEQ ID NO:6981 5802469 90.00

SEQ ID NO:6934 5772329 86.67 SEQ ID NO:6982 5802541 92.86

SEQ ID NO:6935 5774720 80.00 SEQ ID NO:6983 5802547 92.86

SEQ ID NO:6936 5776388 100.00 SEQ ID NO:6984 5802588 92.86

SEQ ID NO:6937 5777546 100.00 SEQ ID NO:6985 5802591 92.86

SEQ ID NO:6938 5777628 100.00 SEQ ID NO:6986 5802609 92.86

SEQ ID NO:6939 5777722 100.00 SEQ ID NO:6987 5802627 100.00

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SEQ ID NO:6942 5778478 80.00 SEQ ID NO:6990 5802719 92.86

SEQ ID NO:6943 5778852 100.00 SEQ ID NO:6991 5802737 100.00

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SEQ ID NO:6945 5779126 100.00 SEQ ID NO:6993 5802753 92.31

SEQ ID NO:6946 5780533 100.00 SEQ ID NO:6994 5802765 90.91

SEQ ID NO:6947 5781615 100.00 SEQ ID NO:6995 5802767 100.00

SEQ ID NO:6948 5781743 100.00 SEQ ID NO:6996 5802783 92.31

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SEQ ID NO:6950 5783848 100.00 SEQ ID NO:6998 5802802 100.00 SEQ ID NO:6999 5802818 100.00 SEQ ID NO:7047 5812548 85.71

SEQ ID NO:7000 5802822 100.00 SEQ ID NO:7048 5812564 83.33

SEQ ID NO:7001 5802828 100.00 SEQ ID NO:7049 5812575 80.00

SEQ ID NO:7002 5802832 100.00 SEQ ID NO:7050 5812596 85.71

SEQ ID NO:7003 5802842 100.00 SEQ ID NO:7051 5812600 80.00

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SEQ ID NO:7005 5802865 100.00 SEQ ID NO:7053 5812815 71.43

SEQ ID NO:7006 5802881 100.00 SEQ ID NO:7054 5812867 85.71

SEQ ID NO:7007 5803973 100.00 SEQ ID NO:7055 5813064 100.00

SEQ ID NO:7008 5804343 80.00 SEQ ID NO:7056 5813302 100.00

SEQ ID NO:7009 5804351 75.00 SEQ ID NO:7057 5814358 80.00

SEQ ID NO:7010 5804377 83.33 SEQ ID NO:7058 5814838 86.67

SEQ ID NO:7011 5804447 80.00 SEQ ID NO:7059 5814877 86.67

SEQ ID NO:7012 5804494 100.00 SEQ ID NO:7060 5814945 86.67

SEQ ID NO:7013 5804520 90.91 SEQ ID NO:7061 5815946 92.86

SEQ ID NO:7014 5804538 100.00 SEQ ID NO:7062 5815977 92.86

SEQ ID NO:7015 5804637 92.31 SEQ ID NO:7063 5816969 100.00

SEQ ID NO:7016 5804640 90.00 SEQ ID NO:7064 5817719 87.50

SEQ ID NO:7017 5804643 100.00 SEQ ID NO:7065 5820217 100.00

SEQ ID NO:7018 5804653 90.00 SEQ ID NO:7066 5821089 100.00

SEQ ID NO:7019 5804658 92.86 SEQ ID NO:7067 5821094 100.00

SEQ ID NO:7020 5804673 100.00 SEQ ID NO:7068 5821303 92.31

SEQ ID NO:7021 5804705 92.86 SEQ ID NO:7069 5821385 71.43

SEQ ID NO:7022 5804778 85.71 SEQ ID NO:7070 5821435 75.00

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SEQ ID NO:9345 6994506 72.73 SEQ ID NO:9393 7015958 92.31

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SEQ ID NO:9977 7267225 86.67 SEQ ID NO 10025 7310242 78.57

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SEQ ID NO:9987 7283677 91.67 SEQ ID NO 10035 7313716 78.57

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SEQ ID NO:9989 7285024 86.67 SEQ ID NO 10037 7319130 80.00

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SEQ ID NO:9991 7285860 72.73 SEQ ID NO 10039 7322920 80.00

SEQ ID NO:9992 7285896 78.57 SEQ ID NO 10040 7323497 78.57

SEQ ID NO:9993 7286096 80.00 SEQ ID NO 10041 7324829 80.00

SEQ ID NO:9994 7286133 76.92 SEQ ID NO 10042 7324919 83.33

SEQ ID NO:9995 7286150 78.57 SEQ ID NO 10043 7325063 80.00

SEQ ID NO:9996 7286153 78.57 SEQ ID NO 10044 7330381 78.57

SEQ ID NO:9997 7286421 80.00 SEQ ID NO 10045 7331873 80.00

SEQ ID NO:9998 7287821 80.00 SEQ ID NO 10046 7331942 80.00

SEQ ID NO:9999 7288018 80.00 SEQ ID NO 10047 7332307 78.57

SEQ ID NO: 10000 7288626 80.00 SEQ ID NO 10048 7332350 78.57

SEQ ID NO: 10001 7289257 80.00 SEQ ID NO 10049 7332799 85.71

SEQ ID NO: 10002 7289969 80.00 SEQ ID NO 10050 7332820 90.91

SEQ ID NO: 10003 7290871 78.57 SEQ ID NO 10051 7332834 87.50

SEQ ID NO: 10004 7295686 91.67 SEQ ID NO 10052 7332840 78.57

SEQ ID NO: 10005 7296274 80.00 SEQ ID NO 10053 7332857 80.00

SEQ ID NO: 10006 7298448 88.89 SEQ ID NO 10054 7332935 78.57

SEQ ID NO: 10007 7299452 85.71 SEQ ID NO 10055 7332993 81.82

SEQ ID NO: 10008 7299962 78.57 SEQ ID NO 10056 7332998 76.92

SEQ ID NO: 10009 7300265 86.67 SEQ ID NO 10057 7333000 75.00

SEQ ID NO: 10010 7300458 80.00 SEQ ID NO 10058 7333034 76.92

SEQ ID NO: 10011 7301454 78.57 SEQ ID NO 10059 7333255 100.00

SEQ ID NO: 10012 7303762 76.92 SEQ ID NO 10060 7333326 80.00

SEQ ID NO: 10013 7303853 84.62 SEQ ID NO 10061 7333464 80.00

SEQ ID NO: 10014 7304926 83.33 SEQ ID NO 10062 7333519 75.00

SEQ ID NO: 10015 7304969 90.91 SEQ ID NO 10063 7333572 70.00

SEQ ID NO: 10016 7304991 90.91 SEQ ID NO 10064 7333580 90.91

SEQ ID NO: 10017 7305245 100.00 SEQ ID NO 10065 7333602 80.00

SEQ ID NO: 10018 7307266 80.00 SEQ ID NO 10066 7333608 80.00

SEQ ID NO: 10019 7309697 78.57 SEQ ID NO 10067 7333614 80.00

SEQ ID NO: 10020 7309808 78.57 SEQ ID NO 10068 7333751 80.00

SEQ ID NO: 10021 7309818 78.57 SEQ ID NO 10069 7333883 80.00

SEQ ID NO: 10022 7310046 80.00 SEQ ID NO 10070 7333923 92.86 SEQ ID NO 10071 7333963 100.00 SEQ ID NO 10119 7337210 76.92

SEQ ID NO 10072 7333966 75.00 SEQ ID NO 10120 7337251 78.57

SEQ ID NO 10073 7333998 86.67 SEQ ID NO 10121 7337269 80.00

SEQ ID NO 10074 7334002 83.33 SEQ ID NO 10122 7337364 93.33

SEQ ID NO 10075 7334015 84.62 SEQ ID NO 10123 7337415 78.57

SEQ ID NO 10076 7334065 83.33 SEQ ID NO 10124 7337439 90.00

SEQ ID NO 10077 7334073 100.00 SEQ ID NO 10125 7337632 93.33

SEQ ID NO 10078 7334115 100.00 SEQ ID NO 10126 7337679 73.33

SEQ ID NO 10079 7334141 90.00 SEQ ID NO 10127 7337684 88.89

SEQ ID NO 10080 7334168 85.71 SEQ ID NO 10128 7337701 78.57

SEQ ID NO 10081 7334209 100.00 SEQ ID NO 10129 7337738 78.57

SEQ ID NO 10082 7334216 80.00 SEQ ID NO 10130 7337765 93.33

SEQ ID NO 10083 7334217 100.00 SEQ ID NO 10131 7337892 80.00

SEQ ID NO 10084 7334293 100.00 SEQ ID NO 10132 7338053 75.00

SEQ ID NO 10085 7334616 75.00 SEQ ID NO 10133 7339440 80.00

SEQ ID NO 10086 7334714 75.00 SEQ ID NO 10134 7340910 78.57

SEQ ID NO 10087 7334732 71.43 SEQ ID NO 10135 7341281 80.00

SEQ ID NO 10088 7334743 85.71 SEQ ID NO 10136 7353832 100.00

SEQ ID NO 10089 7334783 85.71 SEQ ID NO 10137 7354449 80.00

SEQ ID NO 10090 7334889 100.00 SEQ ID NO 10138 7354563 78.57

SEQ ID NO 10091 7334917 100.00 SEQ ID NO 10139 7354987 78.57

SEQ ID NO 10092 7334922 100.00 SEQ ID NO 10140 7355078 80.00

SEQ ID NO 10093 7334965 100.00 SEQ ID NO 10141 7355092 80.00

SEQ ID NO 10094 7335043 90.91 SEQ ID NO 10142 7355104 80.00

SEQ ID NO 10095 7335109 80.00 SEQ ID NO 10143 7355114 80.00

SEQ ID NO 10096 7335195 100.00 SEQ ID NO 10144 7356165 80.00

SEQ ID NO 10097 7335434 75.00 SEQ ID NO 10145 7356327 78.57

SEQ ID NO 10098 7335668 85.71 SEQ ID NO 10146 7356526 100.00

SEQ ID NO 10099 7335675 100.00 SEQ ID NO 10147 7356554 100.00

SEQ ID NO 10100 7335718 75.00 SEQ ID NO 10148 7356565 100.00

SEQ ID NO 10101 7335763 90.00 SEQ ID NO 10149 7356604 100.00

SEQ ID NO 10102 7335975 87.50 SEQ ID NO 10150 7357249 83.33

SEQ ID NO 10103 7335999 80.00 SEQ ID NO 10151 7357758 80.00

SEQ ID NO 10104 7336034 87.50 SEQ ID NO 10152 7358107 75.00

SEQ ID NO 10105 7336100 100.00 SEQ ID NO 10153 7358453 80.00

SEQ ID NO 10106 7336403 80.00 SEQ ID NO 10154 7358888 80.00

SEQ ID NO 10107 7336485 83.33 SEQ ID NO 10155 7361833 83.33

SEQ ID NO 10108 7336572 80.00 SEQ ID NO 10156 7361919 80.00

SEQ ID NO 10109 7336599 75.00 SEQ ID NO 10157 7362021 100.00

SEQ ID NO 10110 7336714 100.00 SEQ ID NO 10158 7362049 87.50

SEQ ID NO 10111 7336742 100.00 SEQ ID NO 10159 7362160 83.33

SEQ ID NO 10112 7336775 100.00 SEQ ID NO 10160 7362656 73.33

SEQ ID NO 10113 7336831 100.00 SEQ ID NO 10161 7363270 80.00

SEQ ID NO 10114 7336840 75.00 SEQ ID NO 10162 7363345 78.57

SEQ ID NO 10115 7336974 80.00 SEQ ID NO 10163 7363396 80.00

SEQ ID NO 10116 7337070 91.67 SEQ ID NO 10164 7363443 80.00

SEQ ID NO 10117 7337116 78.57 SEQ ID NO 10165 7363776 80.00

SEQ ID NO 10118 7337161 75.00 SEQ ID NO 10166 7363807 100.00 SEQ ID NO 10167 7363934 100.00 SEQ ID NO 10215 7380201 72.73

SEQ ID NO 10168 7364565 100.00 SEQ ID NO 10216 7380262 80.00

SEQ ID NO 10169 7365328 100.00 SEQ ID NO 10217 7380268 78.57

SEQ ID NO 10170 7365352 75.00 SEQ ID NO 10218 7380307 78.57

SEQ ID NO 10171 7365361 75.00 SEQ ID NO 10219 7380586 76.92

SEQ ID NO 10172 7365618 78.57 SEQ ID NO 10220 7380606 78.57

SEQ ID NO 10173 7365779 78.57 SEQ ID NO 10221 7380761 78.57

SEQ ID NO 10174 7366020 72.73 SEQ ID NO 10222 7380827 78.57

SEQ ID NO 10175 7366133 78.57 SEQ ID NO 10223 7381021 100.00

SEQ ID NO 10176 7366242 76.92 SEQ ID NO 10224 7381071 88.89

SEQ ID NO 10177 7366371 78.57 SEQ ID NO 10225 7381120 83.33

SEQ ID NO 10178 7366570 75.00 SEQ ID NO 10226 7381312 100.00

SEQ ID NO 10179 7367452 80.00 SEQ ID NO 10227 7386613 75.00

SEQ ID NO 10180 7367575 78.57 SEQ ID NO 10228 7386777 87.50

SEQ ID NO 10181 7367734 80.00 SEQ ID NO 10229 7386962 100.00

SEQ ID NO 10182 7368333 78.57 SEQ ID NO 10230 7387162 85.71

SEQ ID NO 10183 7368909 75.00 SEQ ID NO 10231 7387395 83.33

SEQ ID NO 10184 7369359 80.00 SEQ ID NO 10232 7387402 92.86

SEQ ID NO 10185 7369491 76.92 SEQ ID NO 10233 7387405 92.86

SEQ ID NO 10186 7369594 78.57 SEQ ID NO 10234 7387416 92.31

SEQ ID NO 10187 7369640 78.57 SEQ ID NO 10235 7387428 92.86

SEQ ID NO 10188 7370304 80.00 SEQ ID NO 10236 7387447 88.89

SEQ ID NO 10189 7370336 78.57 SEQ ID NO 10237 7387451 91.67

SEQ ID NO 10190 7370392 78.57 SEQ ID NO 10238 7387472 80.00

SEQ ID NO 10191 7370405 80.00 SEQ ID NO 10239 7387489 90.00

SEQ ID NO 10192 7371403 78.57 SEQ ID NO 10240 7387569 92.31

SEQ ID NO 10193 7371974 73.33 SEQ ID NO 10241 7387632 100.00

SEQ ID NO 10194 7372177 80.00 SEQ ID NO 10242 7387658 90.91

SEQ ID NO 10195 7372572 78.57 SEQ ID NO 10243 7387678 87.50

SEQ ID NO 10196 7372649 78.57 SEQ ID NO 10244 7387687 75.00

SEQ ID NO 10197 7373183 73.33 SEQ ID NO 10245 7387720 100.00

SEQ ID NO 10198 7373202 80.00 SEQ ID NO 10246 7387725 100.00

SEQ ID NO 10199 7373460 78.57 SEQ ID NO 10247 7387752 75.00

SEQ ID NO 10200 7373522 90.91 SEQ ID NO 10248 7387840 90.91

SEQ ID NO 10201 7374138 78.57 SEQ ID NO 10249 7387911 93.33

SEQ ID NO 10202 7374279 77.78 SEQ ID NO 10250 7388026 92.86

SEQ ID NO 10203 7374327 78.57 SEQ ID NO 10251 7388053 80.00

SEQ ID NO 10204 7374554 78.57 SEQ ID NO 10252 7388099 100.00

SEQ ID NO 10205 7375092 78.57 SEQ ID NO 10253 7388105 85.71

SEQ ID NO 10206 7375365 93.33 SEQ ID NO 10254 7390724 100.00

SEQ ID NO 10207 7375369 80.00 SEQ ID NO 10255 7390831 100.00

SEQ ID NO 10208 7375847 80.00 SEQ ID NO 10256 7391092 75.00

SEQ ID NO 10209 7376332 100.00 SEQ ID NO 10257 7391124 80.00

SEQ ID NO 10210 7379752 78.57 SEQ ID NO 10258 7391150 88.89

SEQ ID NO 10211 7379944 80.00 SEQ ID NO 10259 7391175 83.33

SEQ ID NO 10212 7379954 92.86 SEQ ID NO 10260 7391243 91.67

SEQ ID NO 10213 7380147 76.92 SEQ ID NO 10261 7391266 80.00

SEQ ID NO 10214 7380161 81.82 SEQ ID NO 10262 7391284 92.31 SEQ ID NO 10263 7391294 92.86 SEQ ID NO 10311 7396513 76.92

SEQ ID NO 10264 7391322 92.86 SEQ ID NO 10312 7396593 78.57

SEQ ID NO 10265 7391422 92.31 SEQ ID NO 10313 7396611 78.57

SEQ ID NO 10266 7391461 92.86 SEQ ID NO 10314 7396681 80.00

SEQ ID NO 10267 7391550 92.86 SEQ ID NO 10315 7397664 73.33

SEQ ID NO 10268 7391575 92.86 SEQ ID NO 10316 7397935 75.00

SEQ ID NO 10269 7391582 92.86 SEQ ID NO 10317 7398144 78.57

SEQ ID NO 10270 7391588 92.86 SEQ ID NO 10318 7398305 75.00

SEQ ID NO 10271 7391599 100.00 SEQ ID NO 10319 7399388 100.00

SEQ ID NO 10272 7391648 92.86 SEQ ID NO 10320 7399430 83.33

SEQ ID NO 10273 7391665 92.86 SEQ ID NO 10321 7399468 78.57

SEQ ID NO 10274 7391691 92.86 SEQ ID NO 10322 7399525 73.33

SEQ ID NO 10275 7391730 90.91 SEQ ID NO 10323 7399539 72.73

SEQ ID NO 10276 7391741 91.67 SEQ ID NO 10324 7399554 78.57

SEQ ID NO 10277 7391844 80.00 SEQ ID NO 10325 7399582 78.57

SEQ ID NO 10278 7391846 88.89 SEQ ID NO 10326 7399594 78.57

SEQ ID NO 10279 7392021 83.33 SEQ ID NO 10327 7399683 78.57

SEQ ID NO 10280 7392024 80.00 SEQ ID NO 10328 7399785 78.57

SEQ ID NO 10281 7392084 75.00 SEQ ID NO 10329 7399999 78.57

SEQ ID NO 10282 7392156 100.00 SEQ ID NO 10330 7400089 78.57

SEQ ID NO 10283 7392410 100.00 SEQ ID NO 10331 7400109 78.57

SEQ ID NO 10284 7392515 75.00 SEQ ID NO 10332 7400135 78.57

SEQ ID NO 10285 7392553 83.33 SEQ ID NO 10333 7400247 80.00

SEQ ID NO 10286 7392561 80.00 SEQ ID NO 10334 7400293 78.57

SEQ ID NO 10287 7392614 75.00 SEQ ID NO 10335 7400297 75.00

SEQ ID NO 10288 7392722 87.50 SEQ ID NO 10336 7400425 78.57

SEQ ID NO 10289 7392917 88.89 SEQ ID NO 10337 7400625 78.57

SEQ ID NO 10290 7392963 75.00 SEQ ID NO 10338 7400761 78.57

SEQ ID NO 10291 7392979 80.00 SEQ ID NO 10339 7400785 78.57

SEQ ID NO 10292 7392989 85.71 SEQ ID NO 10340 7400961 72.73

SEQ ID NO 10293 7393029 90.91 SEQ ID NO 10341 7401027 78.57

SEQ ID NO 10294 7393049 87.50 SEQ ID NO 10342 7401041 78.57

SEQ ID NO 10295 7393193 100.00 SEQ ID NO 10343 7401245 76.92

SEQ ID NO 10296 7393268 83.33 SEQ ID NO 10344 7401269 73.33

SEQ ID NO 10297 7393274 88.89 SEQ ID NO 10345 7402913 78.57

SEQ ID NO 10298 7393286 91.67 SEQ ID NO 10346 7402931 78.57

SEQ ID NO 10299 7393507 75.00 SEQ ID NO 10347 7403520 78.57

SEQ ID NO 10300 7393511 81.82 SEQ ID NO 10348 7404569 76.92

SEQ ID NO 10301 7393926 78.57 SEQ ID NO 10349 7404609 76.92

SEQ ID NO 10302 7393949 78.57 SEQ ID NO 10350 7404896 76.92

SEQ ID NO 10303 7395065 76.92 SEQ ID NO 10351 7405202 78.57

SEQ ID NO 10304 7395083 76.92 SEQ ID NO 10352 7405231 80.00

SEQ ID NO 10305 7395946 78.57 SEQ ID NO 10353 7405370 78.57

SEQ ID NO 10306 7396041 87.50 SEQ ID NO 10354 7405583 78.57

SEQ ID NO 10307 7396077 85.71 SEQ ID NO 10355 7405738 78.57

SEQ ID NO 10308 7396142 85.71 SEQ ID NO 10356 7405762 78.57

SEQ ID NO 10309 7396289 78.57 SEQ ID NO 10357 7405991 78.57

SEQ ID NO 10310 7396306 78.57 SEQ ID NO 10358 7406048 78.57 SEQ ID NO 10359 7406143 78.57 SEQ ID NO 10407 7422789 78.57

SEQ ID NO 10360 7406244 73.33 SEQ ID NO 10408 7423069 78.57

SEQ ID NO 10361 7407368 78.57 SEQ ID NO 10409 7423291 78.57

SEQ ID NO 10362 7407823 78.57 SEQ ID NO 10410 7423792 80.00

SEQ ID NO 10363 7408048 78.57 SEQ ID NO 10411 7423836 93.33

SEQ ID NO 10364 7408155 78.57 SEQ ID NO 10412 7423854 93.33

SEQ ID NO 10365 7408442 75.00 SEQ ID NO 10413 7423862 80.00

SEQ ID NO 10366 7409136 78.57 SEQ ID NO 10414 7423939 73.33

SEQ ID NO 10367 7409209 78.57 SEQ ID NO 10415 7424678 76.92

SEQ ID NO 10368 7409576 73.33 SEQ ID NO 10416 7424717 78.57

SEQ ID NO 10369 7410609 78.57 SEQ ID NO 10417 7425187 73.33

SEQ ID NO 10370 7411130 78.57 SEQ ID NO 10418 7425214 78.57

SEQ ID NO 10371 7411170 78.57 SEQ ID NO 10419 7425444 78.57

SEQ ID NO 10372 7412078 73.33 SEQ ID NO 10420 7425980 100.00

SEQ ID NO 10373 7412190 78.57 SEQ ID NO 10421 7426631 78.57

SEQ ID NO 10374 7412701 73.33 SEQ ID NO 10422 7426680 78.57

SEQ ID NO 10375 7412736 78.57 SEQ ID NO 10423 7426957 75.00

SEQ ID NO 10376 7412847 78.57 SEQ ID NO 10424 7427109 73.33

SEQ ID NO 10377 7412929 78.57 SEQ ID NO 10425 7427178 76.92

SEQ ID NO 10378 7412954 72.73 SEQ ID NO 10426 7427325 78.57

SEQ ID NO 10379 7413351 78.57 SEQ ID NO 10427 7427386 78.57

SEQ ID NO 10380 7413678 70.00 SEQ ID NO 10428 7427561 88.89

SEQ ID NO 10381 7413888 73.33 SEQ ID NO 10429 7427600 100.00

SEQ ID NO 10382 7414037 78.57 SEQ ID NO 10430 7427809 78.57

SEQ ID NO 10383 7414107 78.57 SEQ ID NO 10431 7427926 75.00

SEQ ID NO 10384 7414112 78.57 SEQ ID NO 10432 7428099 78.57

SEQ ID NO 10385 7414260 73.33 SEQ ID NO 10433 7429139 78.57

SEQ ID NO 10386 7414377 73.33 SEQ ID NO 10434 7429215 76.92

SEQ ID NO 10387 7414463 76.92 SEQ ID NO 10435 7429218 78.57

SEQ ID NO 10388 7415379 87.50 SEQ ID NO 10436 7429804 78.57

SEQ ID NO 10389 7418002 78.57 SEQ ID NO 10437 7430082 78.57

SEQ ID NO 10390 7418315 78.57 SEQ ID NO 10438 7430518 100.00

SEQ ID NO 10391 7418533 70.00 SEQ ID NO 10439 7430531 100.00

SEQ ID NO 10392 7418618 75.00 SEQ ID NO 10440 7430539 100.00

SEQ ID NO 10393 7418778 78.57 SEQ ID NO 10441 7430560 100.00

SEQ ID NO 10394 7419133 75.00 SEQ ID NO 10442 7430608 85.71

SEQ ID NO 10395 7420038 78.57 SEQ ID NO 10443 7430715 100.00

SEQ ID NO 10396 7420174 78.57 SEQ ID NO 10444 7430719 75.00

SEQ ID NO 10397 7420242 78.57 SEQ ID NO 10445 7430722 100.00

SEQ ID NO 10398 7420521 78.57 SEQ ID NO 10446 7430751 83.33

SEQ ID NO 10399 7420556 76.92 SEQ ID NO 10447 7430756 85.71

SEQ ID NO 10400 7420826 73.33 SEQ ID NO 10448 7433198 100.00

SEQ ID NO 10401 7420858 78.57 SEQ ID NO 10449 7433387 75.00

SEQ ID NO 10402 7420979 78.57 SEQ ID NO 10450 7438245 78.57

SEQ ID NO 10403 7421041 78.57 SEQ ID NO 10451 7438301 73.33

SEQ ID NO 10404 7421239 73.33 SEQ ID NO 10452 7438336 78.57

SEQ ID NO 10405 7421369 78.57 SEQ ID NO 10453 7438370 78.57

SEQ ID NO 10406 7422039 78.57 SEQ ID NO 10454 7438383 78.57 SEQ ID NO 10455 7438412 78.57 SEQ ID NO 10503 7465344 80.00

SEQ ID NO 10456 7438419 80.00 SEQ ID NO 10504 7465385 80.00

SEQ ID NO 10457 7438487 73.33 SEQ ID NO 10505 7465439 80.00

SEQ ID NO 10458 7438810 73.33 SEQ ID NO 10506 7465633 75.00

SEQ ID NO 10459 7439052 73.33 SEQ ID NO 10507 7466086 78.57

SEQ ID NO 10460 7439080 73.33 SEQ ID NO 10508 7466193 78.57

SEQ ID NO 10461 7439801 80.00 SEQ ID NO 10509 7466567 80.00

SEQ ID NO 10462 7439925 100.00 SEQ ID NO 10510 7466746 80.00

SEQ ID NO 10463 7446957 71.43 SEQ ID NO 10511 7466753 78.57

SEQ ID NO 10464 7448003 73.33 SEQ ID NO 10512 7466931 80.00

SEQ ID NO 10465 7448171 85.71 SEQ ID NO 10513 7467074 93.33

SEQ ID NO 10466 7450729 100.00 SEQ ID NO 10514 7467360 78.57

SEQ ID NO 10467 7453230 90.00 SEQ ID NO 10515 7467950 80.00

SEQ ID NO 10468 7453261 80.00 SEQ ID NO 10516 7468269 80.00

SEQ ID NO 10469 7454321 100.00 SEQ ID NO 10517 7468497 92.31

SEQ ID NO 10470 7454399 87.50 SEQ ID NO 10518 7468978 91.67

SEQ ID NO 10471 7454404 91.67 SEQ ID NO 10519 7469323 78.57

SEQ ID NO 10472 7454683 88.89 SEQ ID NO 10520 7469497 80.00

SEQ ID NO 10473 7455352 100.00 SEQ ID NO 10521 7469860 80.00

SEQ ID NO 10474 7455484 87.50 SEQ ID NO 10522 7469866 80.00

SEQ ID NO 10475 7455524 83.33 SEQ ID NO 10523 7470000 80.00

SEQ ID NO 10476 7455585 100.00 SEQ ID NO 10524 7470024 80.00

SEQ ID NO 10477 7457503 100.00 SEQ ID NO 10525 7470550 80.00

SEQ ID NO 10478 7457651 75.00 SEQ ID NO 10526 7470706 80.00

SEQ ID NO 10479 7458920 100.00 SEQ ID NO 10527 7470711 78.57

SEQ ID NO 10480 7459246 88.89 SEQ ID NO 10528 7470793 93.33

SEQ ID NO 10481 7460436 100.00 SEQ ID NO 10529 7471075 80.00

SEQ ID NO 10482 7460796 73.33 SEQ ID NO 10530 7471119 80.00

SEQ ID NO 10483 7460828 73.33 SEQ ID NO 10531 7471182 78.57

SEQ ID NO 10484 7461310 75.00 SEQ ID NO 10532 7471352 80.00

SEQ ID NO 10485 7461786 78.57 SEQ ID NO 10533 7472106 87.50

SEQ ID NO 10486 7462110 78.57 SEQ ID NO 10534 7472144 100.00

SEQ ID NO 10487 7462216 76.92 SEQ ID NO 10535 7473176 78.57

SEQ ID NO 10488 7462254 78.57 SEQ ID NO 10536 7473489 80.00

SEQ ID NO 10489 7462299 78.57 SEQ ID NO 10537 7473577 80.00

SEQ ID NO 10490 7462330 78.57 SEQ ID NO 10538 7473650 80.00

SEQ ID NO 10491 7462453 87.50 SEQ ID NO 10539 7473807 80.00

SEQ ID NO 10492 7462505 80.00 SEQ ID NO 10540 7473910 80.00

SEQ ID NO 10493 7462973 80.00 SEQ ID NO 10541 7473917 83.33

SEQ ID NO 10494 7463084 80.00 SEQ ID NO 10542 7475263 80.00

SEQ ID NO 10495 7463605 78.57 SEQ ID NO 10543 7475731 90.00

SEQ ID NO 10496 7463787 73.33 SEQ ID NO 10544 7476393 80.00

SEQ ID NO 10497 7463996 76.92 SEQ ID NO 10545 7476453 93.33

SEQ ID NO 10498 7464655 80.00 SEQ ID NO 10546 7476466 92.86

SEQ ID NO 10499 7464830 80.00 SEQ ID NO 10547 7476647 80.00

SEQ ID NO 10500 7464875 80.00 SEQ ID NO 10548 7479845 100.00

SEQ ID NO 10501 7464991 80.00 SEQ ID NO 10549 7480517 100.00

SEQ ID NO 10502 7465127 80.00 SEQ ID NO 10550 7480557 100.00 SEQ ID NO 10551 7481633 75.00 SEQ ID NO 10599 7494672 78.57

SEQ ID NO 10552 7482095 100.00 SEQ ID NO 10600 7495469 80.00

SEQ ID NO 10553 7482404 75.00 SEQ ID NO 10601 7495471 80.00

SEQ ID NO 10554 7482781 100.00 SEQ ID NO 10602 7495518 80.00

SEQ ID NO 10555 7484590 100.00 SEQ ID NO 10603 7495680 80.00

SEQ ID NO 10556 7484617 75.00 SEQ ID NO 10604 7495809 93.33

SEQ ID NO 10557 7485638 80.00 SEQ ID NO 10605 7495914 75.00

SEQ ID NO 10558 7486120 93.33 SEQ ID NO 10606 7495922 93.33

SEQ ID NO 10559 7486159 90.00 SEQ ID NO 10607 7496079 83.33

SEQ ID NO 10560 7486228 80.00 SEQ ID NO 10608 7496398 93.33

SEQ ID NO 10561 7486294 80.00 SEQ ID NO 10609 7496446 93.33

SEQ ID NO 10562 7486559 93.33 SEQ ID NO 10610 7496526 100.00

SEQ ID NO 10563 7486593 75.00 SEQ ID NO 10611 7496761 93.33

SEQ ID NO 10564 7486755 78.57 SEQ ID NO 10612 7496936 78.57

SEQ ID NO 10565 7486960 80.00 SEQ ID NO 10613 7497148 78.57

SEQ ID NO 10566 7486964 80.00 SEQ ID NO 10614 7497206 78.57

SEQ ID NO 10567 7487191 80.00 SEQ ID NO 10615 7497311 78.57

SEQ ID NO 10568 7487285 80.00 SEQ ID NO 10616 7497376 100.00

SEQ ID NO 10569 7487320 80.00 SEQ ID NO 10617 7497884 80.00

SEQ ID NO 10570 7487463 80.00 SEQ ID NO 10618 7497962 80.00

SEQ ID NO 10571 7487466 80.00 SEQ ID NO 10619 7497999 78.57

SEQ ID NO 10572 7487636 78.57 SEQ ID NO 10620 7498032 72.73

SEQ ID NO 10573 7488230 80.00 SEQ ID NO 10621 7498054 92.86

SEQ ID NO 10574 7488381 80.00 SEQ ID NO 10622 7498059 92.86

SEQ ID NO 10575 7488479 80.00 SEQ ID NO 10623 7499020 78.57

SEQ ID NO 10576 7488609 87.50 SEQ ID NO 10624 7499070 75.00

SEQ ID NO 10577 7488846 80.00 SEQ ID NO 10625 7499604 80.00

SEQ ID NO 10578 7488875 80.00 SEQ ID NO 10626 7499625 78.57

SEQ ID NO 10579 7488892 80.00 SEQ ID NO 10627 7499843 93.33

SEQ ID NO 10580 7488954 78.57 SEQ ID NO 10628 7499978 80.00

SEQ ID NO 10581 7489058 93.33 SEQ ID NO 10629 7500037 80.00

SEQ ID NO 10582 7489120 93.33 SEQ ID NO 10630 7500050 93.33

SEQ ID NO 10583 7489937 93.33 SEQ ID NO 10631 7500250 78.57

SEQ ID NO 10584 7490182 90.00 SEQ ID NO 10632 7501182 93.33

SEQ ID NO 10585 7490739 80.00 SEQ ID NO 10633 7501330 85.71

SEQ ID NO 10586 7490776 80.00 SEQ ID NO 10634 7501365 83.33

SEQ ID NO 10587 7490914 78.57 SEQ ID NO 10635 7501382 83.33

SEQ ID NO 10588 7490975 78.57 SEQ ID NO 10636 7501427 83.33

SEQ ID NO 10589 7491133 78.57 SEQ ID NO 10637 7501446 93.33

SEQ ID NO 10590 7491155 78.57 SEQ ID NO 10638 7501458 93.33

SEQ ID NO 10591 7491407 75.00 SEQ ID NO 10639 7501462 75.00

SEQ ID NO 10592 7491529 88.89 SEQ ID NO 10640 7501487 93.33

SEQ ID NO 10593 7491548 90.00 SEQ ID NO 10641 7501502 83.33

SEQ ID NO 10594 7491658 78.57 SEQ ID NO 10642 7501677 93.33

SEQ ID NO 10595 7491879 78.57 SEQ ID NO 10643 7502854 80.00

SEQ ID NO 10596 7491990 78.57 SEQ ID NO 10644 7502864 80.00

SEQ ID NO 10597 7493490 78.57 SEQ ID NO 10645 7503607 78.57

SEQ ID NO 10598 7493563 78.57 SEQ ID NO 10646 7503991 93.33 SEQ ID NO 10647 7504006 93.33 SEQ ID NO 10695 7546669 100.00

SEQ ID NO 10648 7505945 73.33 SEQ ID NO 10696 7546733 75.00

SEQ ID NO 10649 7508085 92.31 SEQ ID NO 10697 7547815 75.00

SEQ ID NO 10650 7509225 78.57 SEQ ID NO 10698 7547863 75.00

SEQ ID NO 10651 7509249 78.57 SEQ ID NO 10699 7547882 75.00

SEQ ID NO 10652 7509313 80.00 SEQ ID NO 10700 7548251 100.00

SEQ ID NO 10653 7509444 85.71 SEQ ID NO 10701 7548310 75.00

SEQ ID NO 10654 7509461 85.71 SEQ ID NO 10702 7551678 80.00

SEQ ID NO 10655 7509512 75.00 SEQ ID NO 10703 7552083 78.57

SEQ ID NO 10656 7514487 80.00 SEQ ID NO 10704 7552417 80.00

SEQ ID NO 10657 7516589 75.00 SEQ ID NO 10705 7552614 78.57

SEQ ID NO 10658 7516785 80.00 SEQ ID NO 10706 7552680 78.57

SEQ ID NO 10659 7521527 80.00 SEQ ID NO 10707 7555301 92.86

SEQ ID NO 10660 7524166 81.82 SEQ ID NO 10708 7555793 83.33

SEQ ID NO 10661 7524408 80.00 SEQ ID NO 10709 7555825 83.33

SEQ ID NO 10662 7524626 73.33 SEQ ID NO 10710 7555847 85.71

SEQ ID NO 10663 7525266 78.57 SEQ ID NO 10711 7556617 78.57

SEQ ID NO 10664 7528646 92.86 SEQ ID NO 10712 7556898 78.57

SEQ ID NO 10665 7529182 100.00 SEQ ID NO 10713 7556912 80.00

SEQ ID NO 10666 7529362 80.00 SEQ ID NO 10714 7556925 80.00

SEQ ID NO 10667 7529546 80.00 SEQ ID NO 10715 7557588 72.73

SEQ ID NO 10668 7529978 80.00 SEQ ID NO 10716 7557887 78.57

SEQ ID NO 10669 7531607 85.71 SEQ ID NO 10717 7558056 78.57

SEQ ID NO 10670 7531734 93.33 SEQ ID NO 10718 7558067 76.92

SEQ ID NO 10671 7532105 80.00 SEQ ID NO 10719 7558076 78.57

SEQ ID NO 10672 7532523 80.00 SEQ ID NO 10720 7558091 90.91

SEQ ID NO 10673 7533581 78.57 SEQ ID NO 10721 7558167 100.00

SEQ ID NO 10674 7536998 78.57 SEQ ID NO 10722 7558222 80.00

SEQ ID NO 10675 7538042 78.57 SEQ ID NO 10723 7558331 83.33

SEQ ID NO 10676 7538607 73.33 SEQ ID NO 10724 7558400 76.92

SEQ ID NO 10677 7540333 80.00 SEQ ID NO 10725 7558420 76.92

SEQ ID NO 10678 7540728 80.00 SEQ ID NO 10726 7558421 72.73

SEQ ID NO 10679 7541195 76.92 SEQ ID NO 10727 7558525 76.92

SEQ ID NO 10680 7543438 75.00 SEQ ID NO 10728 7558531 76.92

SEQ ID NO 10681 7543559 78.57 SEQ ID NO 10729 7558604 88.89

SEQ ID NO 10682 7543698 78.57 SEQ ID NO 10730 7559364 100.00

SEQ ID NO 10683 7543723 76.92 SEQ ID NO 10731 7559404 80.00

SEQ ID NO 10684 7543728 76.92 SEQ ID NO 10732 7559506 88.89

SEQ ID NO 10685 7544044 78.57 SEQ ID NO 10733 7559571 76.92

SEQ ID NO 10686 7544834 75.00 SEQ ID NO 10734 7559823 78.57

SEQ ID NO 10687 7545845 100.00 SEQ ID NO 10735 7559832 78.57

SEQ ID NO 10688 7546000 80.00 SEQ ID NO 10736 7559919 76.92

SEQ ID NO 10689 7546008 78.57 SEQ ID NO 10737 7560485 100.00

SEQ ID NO 10690 7546140 78.57 SEQ ID NO 10738 7560571 80.00

SEQ ID NO 10691 7546263 80.00 SEQ ID NO 10739 7560606 85.71

SEQ ID NO 10692 7546344 100.00 SEQ ID NO 10740 7560669 100.00

SEQ ID NO 10693 7546470 100.00 SEQ ID NO 10741 7560778 100.00

SEQ ID NO 10694 7546572 80.00 SEQ ID NO 10742 7560902 100.00 SEQ ID NO 10743 7562824 100.00 SEQ ID NO 10791 7604749 80.00

SEQ ID NO 10744 7562825 100.00 SEQ ID NO 10792 7605789 85.71

SEQ ID NO 10745 7562852 100.00 SEQ ID NO 10793 7606428 86.67

SEQ ID NO 10746 7562873 75.00 SEQ ID NO 10794 7607156 86.67

SEQ ID NO 10747 7562908 100.00 SEQ ID NO 10795 7607219 86.67

SEQ ID NO 10748 7562936 100.00 SEQ ID NO 10796 7607283 86.67

SEQ ID NO 10749 7562947 100.00 SEQ ID NO 10797 7609693 88.89

SEQ ID NO 10750 7562967 100.00 SEQ ID NO 10798 7611182 75.00

SEQ ID NO 10751 7576826 100.00 SEQ ID NO 10799 7612163 80.00

SEQ ID NO 10752 7579686 100.00 SEQ ID NO 10800 7613957 86.67

SEQ ID NO 10753 7579845 100.00 SEQ ID NO 10801 7616781 85.71

SEQ ID NO 10754 7579872 100.00 SEQ ID NO 10802 7617932 80.00

SEQ ID NO 10755 7579892 100.00 SEQ ID NO 10803 7618053 84.62

SEQ ID NO 10756 7579931 75.00 SEQ ID NO 10804 7618115 84.62

SEQ ID NO 10757 7580762 88.89 SEQ ID NO 10805 7618173 86.67

SEQ ID NO 10758 7580766 100.00 SEQ ID NO 10806 7618232 86.67

SEQ ID NO 10759 7583007 85.71 SEQ ID NO 10807 7618536 86.67

SEQ ID NO 10760 7583967 76.92 SEQ ID NO 10808 7619058 83.33

SEQ ID NO 10761 7584027 83.33 SEQ ID NO 10809 7619141 83.33

SEQ ID NO 10762 7584104 80.00 SEQ ID NO 10810 7619316 80.00

SEQ ID NO 10763 7584325 78.57 SEQ ID NO 10811 7619320 80.00

SEQ ID NO 10764 7584371 80.00 SEQ ID NO 10812 7619588 85.71

SEQ ID NO 10765 7584441 80.00 SEQ ID NO 10813 7620127 85.71

SEQ ID NO 10766 7584872 100.00 SEQ ID NO 10814 7620286 75.00

SEQ ID NO 10767 7585530 75.00 SEQ ID NO 10815 7620399 85.71

SEQ ID NO 10768 7585568 75.00 SEQ ID NO 10816 7620520 81.82

SEQ ID NO 10769 7585807 80.00 SEQ ID NO 10817 7621664 86.67

SEQ ID NO 10770 7586344 80.00 SEQ ID NO 10818 7621821 75.00

SEQ ID NO 10771 7586480 80.00 SEQ ID NO 10819 7621928 92.31

SEQ ID NO 10772 7588124 77.78 SEQ ID NO 10820 7621992 87.50

SEQ ID NO 10773 7588246 80.00 SEQ ID NO 10821 7622005 87.50

SEQ ID NO 10774 7588292 92.31 SEQ ID NO 10822 7623009 71.43

SEQ ID NO 10775 7588386 78.57 SEQ ID NO 10823 7623045 92.31

SEQ ID NO 10776 7589522 83.33 SEQ ID NO 10824 7623086 84.62

SEQ ID NO 10777 7592519 100.00 SEQ ID NO 10825 7623521 100.00

SEQ ID NO 10778 7594204 78.57 SEQ ID NO 10826 7624950 85.71

SEQ ID NO 10779 7594312 78.57 SEQ ID NO 10827 7625025 86.67

SEQ ID NO 10780 7594433 78.57 SEQ ID NO 10828 7627238 85.71

SEQ ID NO 10781 7597587 85.71 SEQ ID NO 10829 7628532 86.67

SEQ ID NO 10782 7597782 75.00 SEQ ID NO 10830 7630875 86.67

SEQ ID NO 10783 7597979 80.00 SEQ ID NO 10831 7632411 80.00

SEQ ID NO 10784 7598214 71.43 SEQ ID NO 10832 7632424 80.00

SEQ ID NO 10785 7599050 73.33 SEQ ID NO 10833 7636504 80.00

SEQ ID NO 10786 7600282 86.67 SEQ ID NO 10834 7636506 80.00

SEQ ID NO 10787 7600287 86.67 SEQ ID NO 10835 7636848 80.00

SEQ ID NO 10788 7600322 86.67 SEQ ID NO 10836 7637552 85.71

SEQ ID NO 10789 7600648 84.62 SEQ ID NO 10837 7637927 86.67

SEQ ID NO 10790 7604583 70.00 SEQ ID NO 10838 7639021 85.71 SEQ ID NO 10839 7643716 86.67 SEQ ID NO 10887 7717606 80.00

SEQ ID NO 10840 7644074 80.00 SEQ ID NO 10888 7722161 86.67

SEQ ID NO 10841 7644130 80.00 SEQ ID NO 10889 7725014 100.00

SEQ ID NO 10842 7644312 86.67 SEQ ID NO 10890 7727254 100.00

SEQ ID NO 10843 7645077 85.71 SEQ ID NO 10891 7729388 100.00

SEQ ID NO 10844 7645296 84.62 SEQ ID NO 10892 7730403 80.00

SEQ ID NO 10845 7645420 85.71 SEQ ID NO 10893 7730411 75.00

SEQ ID NO 10846 7645442 86.67 SEQ ID NO 10894 7730514 80.00

SEQ ID NO 10847 7645783 85.71 SEQ ID NO 10895 7731004 100.00

SEQ ID NO 10848 7648295 81.82 SEQ ID NO 10896 7731521 100.00

SEQ ID NO 10849 7650156 70.00 SEQ ID NO 10897 7731542 100.00

SEQ ID NO 10850 7650592 85.71 SEQ ID NO 10898 7735274 100.00

SEQ ID NO 10851 7655189 84.62 SEQ ID NO 10899 7754818 80.00

SEQ ID NO 10852 7663226 90.91 SEQ ID NO 10900 7755066 80.00

SEQ ID NO 10853 7663329 100.00 SEQ ID NO 10901 7769418 85.71

SEQ ID NO 10854 7665076 100.00 SEQ ID NO 10902 7769937 76.92

SEQ ID NO 10855 7665089 100.00 SEQ ID NO 10903 7771621 100.00

SEQ ID NO 10856 7665296 100.00 SEQ ID NO 10904 7771652 100.00

SEQ ID NO 10857 7666384 80.00 SEQ ID NO 10905 7775877 80.00

SEQ ID NO 10858 7666537 76.92 SEQ ID NO 10906 7776061 91.67

SEQ ID NO 10859 7666797 80.00 SEQ ID NO 10907 7776135 92.31

SEQ ID NO 10860 7667142 80.00 SEQ ID NO 10908 7776164 100.00

SEQ ID NO 10861 7668108 80.00 SEQ ID NO 10909 7776297 80.00

SEQ ID NO 10862 7668374 100.00 SEQ ID NO 10910 7789034 85.71

SEQ ID NO 10863 7669359 87.50 SEQ ID NO 10911 7793657 84.62

SEQ ID NO 10864 7669586 86.67 SEQ ID NO 10912 7796320 93.33

SEQ ID NO 10865 7669718 93.33 SEQ ID NO 10913 7796393 78.57

SEQ ID NO 10866 7669768 93.33 SEQ ID NO 10914 7800804 93.33

SEQ ID NO 10867 7669809 80.00 SEQ ID NO 10915 7805594 100.00

SEQ ID NO 10868 7671981 80.00 SEQ ID NO 10916 7805645 90.00

SEQ ID NO 10869 7672378 84.62 SEQ ID NO 10917 7805757 87.50

SEQ ID NO 10870 7673443 92.31 SEQ ID NO 10918 7807457 80.00

SEQ ID NO 10871 7676448 90.00 SEQ ID NO 10919 7810616 100.00

SEQ ID NO 10872 7677204 93.33 SEQ ID NO 10920 7812671 93.33

SEQ ID NO 10873 7677854 93.33 SEQ ID NO 10921 7815796 93.33

SEQ ID NO 10874 7678022 93.33 SEQ ID NO 10922 7815978 93.33

SEQ ID NO 10875 7679041 93.33 SEQ ID NO 10923 7819816 100.00

SEQ ID NO 10876 7679053 93.33 SEQ ID NO 10924 7820473 93.33

SEQ ID NO 10877 7680385 86.67 SEQ ID NO 10925 7820511 93.33

SEQ ID NO 10878 7681022 93.33 SEQ ID NO 10926 7820638 93.33

SEQ ID NO 10879 7681161 86.67 SEQ ID NO 10927 7832854 100.00

SEQ ID NO 10880 7681907 93.33 SEQ ID NO 10928 7834129 75.00

SEQ ID NO 10881 7682886 85.71 SEQ ID NO 10929 7839403 75.00

SEQ ID NO 10882 7698520 86.67 SEQ ID NO 10930 7841143 100.00

SEQ ID NO 10883 7698766 85.71 SEQ ID NO 10931 7842993 93.33

SEQ ID NO 10884 7699121 91.67 SEQ ID NO 10932 7843080 93.33

SEQ ID NO 10885 7702092 85.71 SEQ ID NO 10933 7843086 93.33

SEQ ID NO 10886 7702404 81.82 SEQ ID NO 10934 7844505 85.71 SEQ ID NO 10935 7846984 87.50 SEQ ID NO 10983 7877207 93.33

SEQ ID NO 10936 7847022 75.00 SEQ ID NO 10984 7877240 93.33

SEQ ID NO 10937 7849897 85.71 SEQ ID NO 10985 7877260 93.33

SEQ ID NO 10938 7851336 75.00 SEQ ID NO 10986 7877357 93.33

SEQ ID NO 10939 7853199 87.50 SEQ ID NO 10987 7877399 80.00

SEQ ID NO 10940 7854243 100.00 SEQ ID NO 10988 7877402 83.33

SEQ ID NO 10941 7856337 86.67 SEQ ID NO 10989 7877434 93.33

SEQ ID NO 10942 7857887 80.00 SEQ ID NO 10990 7877446 91.67

SEQ ID NO 10943 7857982 92.86 SEQ ID NO 10991 7877463 92.86

SEQ ID NO 10944 7857989 93.33 SEQ ID NO 10992 7877515 90.91

SEQ ID NO 10945 7858025 75.00 SEQ ID NO 10993 7877533 90.00

SEQ ID NO 10946 7858070 93.33 SEQ ID NO 10994 7877567 90.91

SEQ ID NO 10947 7858087 93.33 SEQ ID NO 10995 7877625 80.00

SEQ ID NO 10948 7858112 93.33 SEQ ID NO 10996 7877681 75.00

SEQ ID NO 10949 7858121 80.00 SEQ ID NO 10997 7877723 92.86

SEQ ID NO 10950 7858194 90.91 SEQ ID NO 10998 7877727 75.00

SEQ ID NO 10951 7858213 91.67 SEQ ID NO 10999 7878497 80.00

SEQ ID NO 10952 7858225 93.33 SEQ ID NO 11000 7878613 93.33

SEQ ID NO 10953 7858233 80.00 SEQ ID NO 11001 7878636 75.00

SEQ ID NO 10954 7858266 93.33 SEQ ID NO 11002 7878640 87.50

SEQ ID NO 10955 7858286 93.33 SEQ ID NO 11003 7878722 92.86

SEQ ID NO 10956 7858292 75.00 SEQ ID NO 11004 7878746 92.86

SEQ ID NO 10957 7858310 93.33 SEQ ID NO 11005 7878761 100.00

SEQ ID NO 10958 7858331 93.33 SEQ ID NO 11006 7878781 93.33

SEQ ID NO 10959 7863663 92.31 SEQ ID NO 11007 7878848 75.00

SEQ ID NO 10960 7863743 93.33 SEQ ID NO 11008 7878881 75.00

SEQ ID NO 10961 7863804 90.91 SEQ ID NO 11009 7879044 75.00

SEQ ID NO 10962 7863808 92.31 SEQ ID NO 11010 7879050 100.00

SEQ ID NO 10963 7864267 100.00 SEQ ID NO 11011 7879085 93.33

SEQ ID NO 10964 7864917 93.33 SEQ ID NO 11012 7879202 93.33

SEQ ID NO 10965 7865273 93.33 SEQ ID NO 11013 7879216 93.33

SEQ ID NO 10966 7865803 93.33 SEQ ID NO 11014 7879234 88.89

SEQ ID NO 10967 7865977 85.71 SEQ ID NO 11015 7879333 93.33

SEQ ID NO 10968 7866599 100.00 SEQ ID NO 11016 7879359 93.33

SEQ ID NO 10969 7866694 100.00 SEQ ID NO 11017 7879387 93.33

SEQ ID NO 10970 7867670 85.71 SEQ ID NO 11018 7879399 88.89

SEQ ID NO 10971 7868414 93.33 SEQ ID NO 11019 7879468 93.33

SEQ ID NO 10972 7868430 93.33 SEQ ID NO 11020 7879477 88.89

SEQ ID NO 10973 7868612 90.00 SEQ ID NO 11021 7879516 93.33

SEQ ID NO 10974 7873511 100.00 SEQ ID NO 11022 7879523 93.33

SEQ ID NO 10975 7873750 92.31 SEQ ID NO 11023 7879565 93.33

SEQ ID NO 10976 7873924 100.00 SEQ ID NO 11024 7879584 75.00

SEQ ID NO 10977 7874135 100.00 SEQ ID NO 11025 7879682 75.00

SEQ ID NO 10978 7874815 93.33 SEQ ID NO 11026 7879787 80.00

SEQ ID NO 10979 7875314 100.00 SEQ ID NO 11027 7879797 75.00

SEQ ID NO 10980 7875777 93.33 SEQ ID NO 11028 7879841 93.33

SEQ ID NO 10981 7875984 93.33 SEQ ID NO 11029 7880012 80.00

SEQ ID NO 10982 7876152 75.00 SEQ ID NO 11030 7880090 83.33 SEQ ID NO 11031 7880093 83.33 SEQ ID NO 11079 7883329 100.00

SEQ ID NO 11032 7880121 93.33 SEQ ID NO 11080 7883356 93.33

SEQ ID NO 11033 7880145 75.00 SEQ ID NO 11081 7883369 93.33

SEQ ID NO 11034 7880168 93.33 SEQ ID NO 11082 7883401 93.33

SEQ ID NO 11035 7880222 75.00 SEQ ID NO 11083 7883440 92.86

SEQ ID NO 11036 7880280 87.50 SEQ ID NO 11084 7883489 91.67

SEQ ID NO 11037 7880369 93.33 SEQ ID NO 11085 7883492 93.33

SEQ ID NO 11038 7880382 80.00 SEQ ID NO 11086 7883508 93.33

SEQ ID NO 11039 7880389 87.50 SEQ ID NO 11087 7883523 93.33

SEQ ID NO 11040 7880435 93.33 SEQ ID NO 11088 7883542 75.00

SEQ ID NO 11041 7880480 93.33 SEQ ID NO 11089 7883566 83.33

SEQ ID NO 11042 7880561 93.33 SEQ ID NO 11090 7883582 90.00

SEQ ID NO 11043 7880644 75.00 SEQ ID NO 11091 7883632 90.91

SEQ ID NO 11044 7880677 75.00 SEQ ID NO 11092 7883657 87.50

SEQ ID NO 11045 7880718 83.33 SEQ ID NO 11093 7883666 87.50

SEQ ID NO 11046 7880834 80.00 SEQ ID NO 11094 7883673 93.33

SEQ ID NO 11047 7880872 75.00 SEQ ID NO 11095 7883694 93.33

SEQ ID NO 11048 7880938 75.00 SEQ ID NO 11096 7883767 93.33

SEQ ID NO 11049 7880961 85.71 SEQ ID NO 11097 7883771 93.33

SEQ ID NO 11050 7880963 75.00 SEQ ID NO 11098 7883810 93.33

SEQ ID NO 11051 7881063 93.33 SEQ ID NO 11099 7883833 93.33

SEQ ID NO 11052 7881138 88.89 SEQ ID NO 11100 7883872 93.33

SEQ ID NO 11053 7881155 87.50 SEQ ID NO 11101 7883901 93.33

SEQ ID NO 11054 7881324 90.91 SEQ ID NO 11102 7883940 93.33

SEQ ID NO 11055 7881329 83.33 SEQ ID NO 11103 7883972 92.31

SEQ ID NO 11056 7881337 85.71 SEQ ID NO 11104 7884025 93.33

SEQ ID NO 11057 7881348 80.00 SEQ ID NO 11105 7884050 93.33

SEQ ID NO 11058 7881363 92.31 SEQ ID NO 11106 7884074 93.33

SEQ ID NO 11059 7881372 92.31 SEQ ID NO 11107 7884160 80.00

SEQ ID NO 11060 7881456 92.86 SEQ ID NO 11108 7884166 93.33

SEQ ID NO 11061 7881483 93.33 SEQ ID NO 11109 7884175 75.00

SEQ ID NO 11062 7881569 92.31 SEQ ID NO 11110 7884324 92.31

SEQ ID NO 11063 7881602 93.33 SEQ ID NO 11111 7884339 75.00

SEQ ID NO 11064 7881644 80.00 SEQ ID NO 11112 7884649 92.86

SEQ ID NO 11065 7881777 93.33 SEQ ID NO 11113 7884750 93.33

SEQ ID NO 11066 7881792 83.33 SEQ ID NO 11114 7884753 75.00

SEQ ID NO 11067 7881799 93.33 SEQ ID NO 11115 7884765 93.33

SEQ ID NO 11068 7881804 93.33 SEQ ID NO 11116 7884798 75.00

SEQ ID NO 11069 7881842 93.33 SEQ ID NO 11117 7884813 93.33

SEQ ID NO 11070 7881847 93.33 SEQ ID NO 11118 7884847 93.33

SEQ ID NO 11071 7881916 90.00 SEQ ID NO 11119 7884852 90.91

SEQ ID NO 11072 7881925 88.89 SEQ ID NO 11120 7884964 72.73

SEQ ID NO 11073 7881960 93.33 SEQ ID NO 11121 7885053 80.00

SEQ ID NO 11074 7881995 88.89 SEQ ID NO 11122 7885080 90.91

SEQ ID NO 11075 7882019 83.33 SEQ ID NO 11123 7885126 100.00

SEQ ID NO 11076 7882840 100.00 SEQ ID NO 11124 7885137 87.50

SEQ ID NO 11077 7883096 80.00 SEQ ID NO 11125 7885184 87.50

SEQ ID NO 11078 7883287 75.00 SEQ ID NO 11126 7885266 93.33 SEQ ID NO 11127 7885283 88.89 SEQ ID NO 11175 7887652 86.67

SEQ ID NO 11128 7885342 93.33 SEQ ID NO 11176 7887685 93.33

SEQ ID NO 11129 7885365 80.00 SEQ ID NO 11177 7887722 93.33

SEQ ID NO 11130 7885391 93.33 SEQ ID NO 11178 7887725 93.33

SEQ ID NO 11131 7885430 93.33 SEQ ID NO 11179 7887732 93.33

SEQ ID NO 11132 7885562 93.33 SEQ ID NO 11180 7887740 75.00

SEQ ID NO 11133 7885569 93.33 SEQ ID NO 11181 7887760 83.33

SEQ ID NO 11134 7885617 75.00 SEQ ID NO 11182 7887798 93.33

SEQ ID NO 11135 7885625 93.33 SEQ ID NO 11183 7887804 93.33

SEQ ID NO 11136 7885633 93.33 SEQ ID NO 11184 7887867 93.33

SEQ ID NO 11137 7885644 91.67 SEQ ID NO 11185 7887889 83.33

SEQ ID NO 11138 7885797 93.33 SEQ ID NO 11186 7888027 75.00

SEQ ID NO 11139 7885832 93.33 SEQ ID NO 11187 7888051 91.67

SEQ ID NO 11140 7885912 92.31 SEQ ID NO 11188 7888084 93.33

SEQ ID NO 11141 7885946 80.00 SEQ ID NO 11189 7888130 93.33

SEQ ID NO 11142 7885991 93.33 SEQ ID NO 11190 7888138 80.00

SEQ ID NO 11143 7885998 93.33 SEQ ID NO 11191 7888173 93.33

SEQ ID NO 11144 7886014 83.33 SEQ ID NO 11192 7888245 93.33

SEQ ID NO 11145 7886016 93.33 SEQ ID NO 11193 7888262 93.33

SEQ ID NO 11146 7886231 75.00 SEQ ID NO 11194 7888267 93.33

SEQ ID NO 11147 7886252 91.67 SEQ ID NO 11195 7888270 80.00

SEQ ID NO 11148 7886283 92.31 SEQ ID NO 11196 7888321 93.33

SEQ ID NO 11149 7886318 93.33 SEQ ID NO 11197 7888424 75.00

SEQ ID NO 11150 7886327 91.67 SEQ ID NO 11198 7888433 75.00

SEQ ID NO 11151 7886392 75.00 SEQ ID NO 11199 7888439 90.91

SEQ ID NO 11152 7886420 93.33 SEQ ID NO 11200 7888458 83.33

SEQ ID NO 11153 7886491 80.00 SEQ ID NO 11201 7888462 93.33

SEQ ID NO 11154 7886508 93.33 SEQ ID NO 11202 7888477 85.71

SEQ ID NO 11155 7886535 93.33 SEQ ID NO 11203 7888623 85.71

SEQ ID NO 11156 7886539 92.86 SEQ ID NO 11204 7888625 85.71

SEQ ID NO 11157 7886541 93.33 SEQ ID NO 11205 7888644 75.00

SEQ ID NO 11158 7886588 93.33 SEQ ID NO 11206 7888868 92.86

SEQ ID NO 11159 7886592 75.00 SEQ ID NO 11207 7888879 93.33

SEQ ID NO 11160 7886663 75.00 SEQ ID NO 11208 7888885 93.33

SEQ ID NO 11161 7886805 93.33 SEQ ID NO 11209 7889213 100.00

SEQ ID NO 11162 7886868 93.33 SEQ ID NO 11210 7890563 93.33

SEQ ID NO 11163 7886938 93.33 SEQ ID NO 11211 7890682 93.33

SEQ ID NO 11164 7886978 75.00 SEQ ID NO 11212 7890741 93.33

SEQ ID NO 11165 7887053 90.91 SEQ ID NO 11213 7891922 75.00

SEQ ID NO 11166 7887194 93.33 SEQ ID NO 11214 7892337 80.00

SEQ ID NO 11167 7887241 87.50 SEQ ID NO 11215 7892348 85.71

SEQ ID NO 11168 7887268 90.00 SEQ ID NO 11216 7892470 93.33

SEQ ID NO 11169 7887338 93.33 SEQ ID NO 11217 7892599 80.00

SEQ ID NO 11170 7887458 75.00 SEQ ID NO 11218 7892752 93.33

SEQ ID NO 11171 7887511 93.33 SEQ ID NO 11219 7894715 92.31

SEQ ID NO 11172 7887540 93.33 SEQ ID NO 11220 7894723 91.67

SEQ ID NO 11173 7887622 80.00 SEQ ID NO 11221 7894726 93.33

SEQ ID NO 11174 7887638 93.33 SEQ ID NO 11222 7894861 90.91 SEQ ID NO 11223 7894864 90.91 SEQ ID NO 11271 7909379 93.33

SEQ ID NO 11224 7894878 93.33 SEQ ID NO 11272 7909391 93.33

SEQ ID NO 11225 7898057 88.89 SEQ ID NO 11273 7909407 93.33

SEQ ID NO 11226 7898084 80.00 SEQ ID NO 11274 7909445 93.33

SEQ ID NO 11227 7898113 85.71 SEQ ID NO 11275 7909451 93.33

SEQ ID NO 11228 7898120 75.00 SEQ ID NO 11276 7909462 93.33

SEQ ID NO 11229 7898187 93.33 SEQ ID NO 11277 7909491 93.33

SEQ ID NO 11230 7898276 93.33 SEQ ID NO 11278 7909947 93.33

SEQ ID NO 11231 7898324 93.33 SEQ ID NO 11279 7909979 75.00

SEQ ID NO 11232 7898362 93.33 SEQ ID NO 11280 7909983 93.33

SEQ ID NO 11233 7898507 93.33 SEQ ID NO 11281 7910045 93.33

SEQ ID NO 11234 7900218 93.33 SEQ ID NO 11282 7910075 93.33

SEQ ID NO 11235 7900423 80.00 SEQ ID NO 11283 7910084 93.33

SEQ ID NO 11236 7900431 100.00 SEQ ID NO 11284 7910119 92.86

SEQ ID NO 11237 7904985 100.00 SEQ ID NO 11285 7910148 92.86

SEQ ID NO 11238 7905170 100.00 SEQ ID NO 11286 7910151 93.33

SEQ ID NO 11239 7906887 91.67 SEQ ID NO 11287 7910167 93.33

SEQ ID NO 11240 7907150 85.71 SEQ ID NO 11288 7910183 80.00

SEQ ID NO 11241 7907161 85.71 SEQ ID NO 11289 7910214 93.33

SEQ ID NO 11242 7907181 87.50 SEQ ID NO 11290 7910389 93.33

SEQ ID NO 11243 7907222 75.00 SEQ ID NO 11291 7910420 75.00

SEQ ID NO 11244 7907227 91.67 SEQ ID NO 11292 7910484 93.33

SEQ ID NO 11245 7907388 75.00 SEQ ID NO 11293 7910495 93.33

SEQ ID NO 11246 7907833 92.86 SEQ ID NO 11294 7911862 93.33

SEQ ID NO 11247 7907969 93.33 SEQ ID NO 11295 7911888 93.33

SEQ ID NO 11248 7908023 93.33 SEQ ID NO 11296 7911920 93.33

SEQ ID NO 11249 7908048 92.86 SEQ ID NO 11297 7912052 93.33

SEQ ID NO 11250 7908130 93.33 SEQ ID NO 11298 7912056 92.86

SEQ ID NO 11251 7908183 88.89 SEQ ID NO 11299 7912079 93.33

SEQ ID NO 11252 7908373 87.50 SEQ ID NO 11300 7912142 93.33

SEQ ID NO 11253 7908746 93.33 SEQ ID NO 11301 7912434 93.33

SEQ ID NO 11254 7908836 93.33 SEQ ID NO 11302 7912493 93.33

SEQ ID NO 11255 7908940 93.33 SEQ ID NO 11303 7912625 83.33

SEQ ID NO 11256 7908975 93.33 SEQ ID NO 11304 7912837 75.00

SEQ ID NO 11257 7908986 93.33 SEQ ID NO 11305 7913243 93.33

SEQ ID NO 11258 7908988 93.33 SEQ ID NO 11306 7913610 93.33

SEQ ID NO 11259 7909004 93.33 SEQ ID NO 11307 7914371 93.33

SEQ ID NO 11260 7909018 93.33 SEQ ID NO 11308 7914810 75.00

SEQ ID NO 11261 7909028 93.33 SEQ ID NO 11309 7914962 93.33

SEQ ID NO 11262 7909082 93.33 SEQ ID NO 11310 7915002 93.33

SEQ ID NO 11263 7909108 93.33 SEQ ID NO 11311 7915487 93.33

SEQ ID NO 11264 7909137 93.33 SEQ ID NO 11312 7915766 93.33

SEQ ID NO 11265 7909145 93.33 SEQ ID NO 11313 7916315 93.33

SEQ ID NO 11266 7909166 93.33 SEQ ID NO 11314 7917375 75.00

SEQ ID NO 11267 7909195 93.33 SEQ ID NO 11315 7917533 88.89

SEQ ID NO 11268 7909239 93.33 SEQ ID NO 11316 7917573 93.33

SEQ ID NO 11269 7909272 75.00 SEQ ID NO 11317 7917578 93.33

SEQ ID NO 11270 7909358 93.33 SEQ ID NO 11318 7917616 75.00 SEQ ID NO 11319 7917839 100.00 SEQ ID NO 11367 7927203 93.33

SEQ ID NO 11320 7919345 93.33 SEQ ID NO 11368 7927240 75.00

SEQ ID NO 11321 7919504 93.33 SEQ ID NO 11369 7927440 85.71

SEQ ID NO 11322 7919696 93.33 SEQ ID NO 11370 7927577 92.86

SEQ ID NO 11323 7919762 93.33 SEQ ID NO 11371 7927855 93.33

SEQ ID NO 11324 7919873 93.33 SEQ ID NO 11372 7927868 93.33

SEQ ID NO 11325 7920102 93.33 SEQ ID NO 11373 7927881 75.00

SEQ ID NO 11326 7920282 93.33 SEQ ID NO 11374 7933466 86.67

SEQ ID NO 11327 7921222 80.00 SEQ ID NO 11375 7935046 72.73

SEQ ID NO 11328 7921239 75.00 SEQ ID NO 11376 7935803 85.71

SEQ ID NO 11329 7921411 75.00 SEQ ID NO 11377 7936451 84.62

SEQ ID NO 11330 7921580 93.33 SEQ ID NO 11378 7937087 80.00

SEQ ID NO 11331 7921677 83.33 SEQ ID NO 11379 7937133 100.00

SEQ ID NO 11332 7921854 93.33 SEQ ID NO 11380 7937221 90.00

SEQ ID NO 11333 7921882 93.33 SEQ ID NO 11381 7937270 85.71

SEQ ID NO 11334 7921934 88.89 SEQ ID NO 11382 7937355 85.71

SEQ ID NO 11335 7921960 93.33 SEQ ID NO 11383 7937441 100.00

SEQ ID NO 11336 7922014 88.89 SEQ ID NO 11384 7937551 80.00

SEQ ID NO 11337 7923222 83.33 SEQ ID NO 11385 7937765 88.89

SEQ ID NO 11338 7923719 93.33 SEQ ID NO 11386 7937987 85.71

SEQ ID NO 11339 7923919 93.33 SEQ ID NO 11387 7938022 85.71

SEQ ID NO 11340 7924590 93.33 SEQ ID NO 11388 7938063 85.71

SEQ ID NO 11341 7924613 93.33 SEQ ID NO 11389 7938184 75.00

SEQ ID NO 11342 7924668 93.33 SEQ ID NO 11390 7938196 76.92

SEQ ID NO 11343 7924758 90.00 SEQ ID NO 11391 7938259 84.62

SEQ ID NO 11344 7924948 93.33 SEQ ID NO 11392 7938304 84.62

SEQ ID NO 11345 7925096 93.33 SEQ ID NO 11393 7938349 83.33

SEQ ID NO 11346 7925145 93.33 SEQ ID NO 11394 7938385 84.62

SEQ ID NO 11347 7925161 93.33 SEQ ID NO 11395 7938523 70.00

SEQ ID NO 11348 7925190 93.33 SEQ ID NO 11396 7938607 71.43

SEQ ID NO 11349 7925199 93.33 SEQ ID NO 11397 7938644 85.71

SEQ ID NO 11350 7925213 93.33 SEQ ID NO 11398 7938790 85.71

SEQ ID NO 11351 7925235 93.33 SEQ ID NO 11399 7938827 86.67

SEQ ID NO 11352 7925275 93.33 SEQ ID NO 11400 7938901 75.00

SEQ ID NO 11353 7925353 93.33 SEQ ID NO 11401 7938947 85.71

SEQ ID NO 11354 7925878 100.00 SEQ ID NO 11402 7939131 72.73

SEQ ID NO 11355 7926078 93.33 SEQ ID NO 11403 7939213 81.82

SEQ ID NO 11356 7926156 93.33 SEQ ID NO 11404 7939228 81.82

SEQ ID NO 11357 7926189 75.00 SEQ ID NO 11405 7939254 75.00

SEQ ID NO 11358 7926250 90.00 SEQ ID NO 11406 7939281 84.62

SEQ ID NO 11359 7926588 93.33 SEQ ID NO 11407 7939465 86.67

SEQ ID NO 11360 7926606 75.00 SEQ ID NO 11408 7939581 75.00

SEQ ID NO 11361 7926613 93.33 SEQ ID NO 11409 7939614 81.82

SEQ ID NO 11362 7926660 75.00 SEQ ID NO 11410 7939656 85.71

SEQ ID NO 11363 7926870 75.00 SEQ ID NO 11411 7939732 85.71

SEQ ID NO 11364 7926945 75.00 SEQ ID NO 11412 7939767 85.71

SEQ ID NO 11365 7927028 93.33 SEQ ID NO 11413 7939827 86.67

SEQ ID NO 11366 7927059 75.00 SEQ ID NO 11414 7939878 86.67 SEQ ID NO 11415 7939924 86.67 SEQ ID NO 11463 7954987 85.71

SEQ ID NO 11416 7939944 86.67 SEQ ID NO 11464 7955055 72.73

SEQ ID NO 11417 7939972 86.67 SEQ ID NO 11465 7955076 85.71

SEQ ID NO 11418 7940009 70.00 SEQ ID NO 11466 7955192 86.67

SEQ ID NO 11419 7940035 86.67 SEQ ID NO 11467 7955322 86.67

SEQ ID NO 11420 7940088 75.00 SEQ ID NO 11468 7955386 80.00

SEQ ID NO 11421 7940101 75.00 SEQ ID NO 11469 7955570 86.67

SEQ ID NO 11422 7940288 85.71 SEQ ID NO 11470 7955641 80.00

SEQ ID NO 11423 7940450 85.71 SEQ ID NO 11471 7955741 86.67

SEQ ID NO 11424 7940506 85.71 SEQ ID NO 11472 7956685 85.71

SEQ ID NO 11425 7940557 85.71 SEQ ID NO 11473 7956759 85.71

SEQ ID NO 11426 7940577 85.71 SEQ ID NO 11474 7956881 85.71

SEQ ID NO 11427 7940628 85.71 SEQ ID NO 11475 7956918 85.71

SEQ ID NO 11428 7940645 85.71 SEQ ID NO 11476 7956937 85.71

SEQ ID NO 11429 7940857 76.92 SEQ ID NO 11477 7956953 84.62

SEQ ID NO 11430 7940938 85.71 SEQ ID NO 11478 7960325 90.91

SEQ ID NO 11431 7941556 80.00 SEQ ID NO 11479 7960375 100.00

SEQ ID NO 11432 7942362 85.71 SEQ ID NO 11480 7960382 75.00

SEQ ID NO 11433 7942437 85.71 SEQ ID NO 11481 7960393 75.00

SEQ ID NO 11434 7942487 85.71 SEQ ID NO 11482 7960395 70.00

SEQ ID NO 11435 7942523 84.62 SEQ ID NO 11483 7960404 81.82

SEQ ID NO 11436 7942532 85.71 SEQ ID NO 11484 7960407 80.00

SEQ ID NO 11437 7942574 85.71 SEQ ID NO 11485 7960448 72.73

SEQ ID NO 11438 7942632 85.71 SEQ ID NO 11486 7960586 83.33

SEQ ID NO 11439 7942974 86.67 SEQ ID NO 11487 7960645 83.33

SEQ ID NO 11440 7942985 86.67 SEQ ID NO 11488 7960739 92.31

SEQ ID NO 11441 7943244 76.92 SEQ ID NO 11489 7960760 83.33

SEQ ID NO 11442 7943337 85.71 SEQ ID NO 11490 7960802 90.00

SEQ ID NO 11443 7943404 85.71 SEQ ID NO 11491 7960806 100.00

SEQ ID NO 11444 7943437 85.71 SEQ ID NO 11492 7960839 90.91

SEQ ID NO 11445 7944406 80.00 SEQ ID NO 11493 7960855 84.62

SEQ ID NO 11446 7945561 100.00 SEQ ID NO 11494 7961604 100.00

SEQ ID NO 11447 7945580 88.89 SEQ ID NO 11495 7964738 84.62

SEQ ID NO 11448 7952309 80.00 SEQ ID NO 11496 7964818 92.86

SEQ ID NO 11449 7953236 85.71 SEQ ID NO 11497 7964893 76.92

SEQ ID NO 11450 7953246 85.71 SEQ ID NO 11498 7964900 75.00

SEQ ID NO 11451 7953330 85.71 SEQ ID NO 11499 7964945 85.71

SEQ ID NO 11452 7953396 75.00 SEQ ID NO 11500 7965122 81.82

SEQ ID NO 11453 7953896 85.71 SEQ ID NO 11501 7965167 85.71

SEQ ID NO 11454 7953927 85.71 SEQ ID NO 11502 7979897 80.00

SEQ ID NO 11455 7954094 76.92 SEQ ID NO 11503 7979915 80.00

SEQ ID NO 11456 7954457 86.67 SEQ ID NO 11504 7979978 75.00

SEQ ID NO 11457 7954501 80.00 SEQ ID NO 11505 7980341 100.00

SEQ ID NO 11458 7954516 85.71 SEQ ID NO 11506 7984430 88.89

SEQ ID NO 11459 7954608 85.71 SEQ ID NO 11507 7987294 80.00

SEQ ID NO 11460 7954778 75.00 SEQ ID NO 11508 7988210 71.43

SEQ ID NO 11461 7954803 75.00 SEQ ID NO 11509 7988259 85.71

SEQ ID NO 11462 7954958 100.00 SEQ ID NO 11510 7988324 85.71 SEQ ID NO 11511 7990580 90.00 SEQ ID NO 11559 8025856 90.00

SEQ ID NO 11512 7992235 85.71 SEQ ID NO 11560 8025898 76.92

SEQ ID NO 11513 7992905 85.71 SEQ ID NO 11561 8026466 86.67

SEQ ID NO 11514 7992925 92.31 SEQ ID NO 11562 8026497 85.71

SEQ ID NO 11515 7993327 80.00 SEQ ID NO 11563 8026843 86.67

SEQ ID NO 11516 7993880 85.71 SEQ ID NO 11564 8026866 85.71

SEQ ID NO 11517 7994944 86.67 SEQ ID NO 11565 8027008 86.67

SEQ ID NO 11518 7997123 85.71 SEQ ID NO 11566 8027025 86.67

SEQ ID NO 11519 7997142 86.67 SEQ ID NO 11567 8027223 86.67

SEQ ID NO 11520 7997737 86.67 SEQ ID NO 11568 8027757 93.33

SEQ ID NO 11521 7997874 83.33 SEQ ID NO 11569 8027860 86.67

SEQ ID NO 11522 7998217 85.71 SEQ ID NO 11570 8028552 86.67

SEQ ID NO 11523 7998227 85.71 SEQ ID NO 11571 8029962 80.00

SEQ ID NO 11524 7998344 85.71 SEQ ID NO 11572 8030074 86.67

SEQ ID NO 11525 7998423 85.71 SEQ ID NO 11573 8030760 85.71

SEQ ID NO 11526 7999552 86.67 SEQ ID NO 11574 8038154 86.67

SEQ ID NO 11527 7999591 85.71 SEQ ID NO 11575 8038263 85.71

SEQ ID NO 11528 8000162 84.62 SEQ ID NO 11576 8038711 100.00

SEQ ID NO 11529 8000173 85.71 SEQ ID NO 11577 8038910 84.62

SEQ ID NO 11530 8000281 85.71 SEQ ID NO 11578 8038913 85.71

SEQ ID NO 11531 8000519 85.71 SEQ ID NO 11579 8038968 85.71

SEQ ID NO 11532 8002331 87.50 SEQ ID NO 11580 8039850 100.00

SEQ ID NO 11533 8003050 75.00 SEQ ID NO 11581 8040577 85.71

SEQ ID NO 11534 8003433 85.71 SEQ ID NO 11582 8040665 86.67

SEQ ID NO 11535 8009521 100.00 SEQ ID NO 11583 8041126 85.71

SEQ ID NO 11536 8013430 100.00 SEQ ID NO 11584 8041221 85.71

SEQ ID NO 11537 8013678 93.33 SEQ ID NO 11585 8041632 76.92

SEQ ID NO 11538 8013944 93.33 SEQ ID NO 11586 8041711 80.00

SEQ ID NO 11539 8014122 86.67 SEQ ID NO 11587 8041760 85.71

SEQ ID NO 11540 8014140 93.33 SEQ ID NO 11588 8041987 72.73

SEQ ID NO 11541 8014390 93.33 SEQ ID NO 11589 8042225 93.33

SEQ ID NO 11542 8014995 90.91 SEQ ID NO 11590 8042231 93.33

SEQ ID NO 11543 8015019 85.71 SEQ ID NO 11591 8042266 85.71

SEQ ID NO 11544 8015026 87.50 SEQ ID NO 11592 8042390 93.33

SEQ ID NO 11545 8016249 85.71 SEQ ID NO 11593 8042420 80.00

SEQ ID NO 11546 8016614 75.00 SEQ ID NO 11594 8042439 83.33

SEQ ID NO 11547 8016723 91.67 SEQ ID NO 11595 8042505 85.71

SEQ ID NO 11548 8016852 84.62 SEQ ID NO 11596 8043517 78.57

SEQ ID NO 11549 8017526 93.33 SEQ ID NO 11597 8043699 80.00

SEQ ID NO 11550 8017579 80.00 SEQ ID NO 11598 8043927 85.71

SEQ ID NO 11551 8025118 86.67 SEQ ID NO 11599 8043977 85.71

SEQ ID NO 11552 8025189 84.62 SEQ ID NO 11600 8044089 85.71

SEQ ID NO 11553 8025301 85.71 SEQ ID NO 11601 8044148 80.00

SEQ ID NO 11554 8025412 83.33 SEQ ID NO 11602 8044245 100.00

SEQ ID NO 11555 8025428 100.00 SEQ ID NO 11603 8045040 87.50

SEQ ID NO 11556 8025507 80.00 SEQ ID NO 11604 8045067 83.33

SEQ ID NO 11557 8025841 100.00 SEQ ID NO 11605 8045341 85.71

SEQ ID NO 11558 8025845 80.00 SEQ ID NO 11606 8045381 93.33 SEQ ID NO 11607 8045392 75.00 SEQ ID NO 11655 8135785 86.67

SEQ ID NO 11608 8045441 91.67 SEQ ID NO 11656 8136079 85.71

SEQ ID NO 11609 8045719 70.00 SEQ ID NO 11657 8136170 86.67

SEQ ID NO 11610 8045777 100.00 SEQ ID NO 11658 8136401 80.00

SEQ ID NO 11611 8046055 85.71 SEQ ID NO 11659 8137573 93.33

SEQ ID NO 11612 8046454 85.71 SEQ ID NO 11660 8137708 93.33

SEQ ID NO 11613 8047657 85.71 SEQ ID NO 11661 8137716 75.00

SEQ ID NO 11614 8048269 85.71 SEQ ID NO 11662 8137720 100.00

SEQ ID NO 11615 8048657 85.71 SEQ ID NO 11663 8137735 91.67

SEQ ID NO 11616 8050034 75.00 SEQ ID NO 11664 8137764 93.33

SEQ ID NO 11617 8053022 85.71 SEQ ID NO 11665 8138793 88.89

SEQ ID NO 11618 8053858 85.71 SEQ ID NO 11666 8139269 85.71

SEQ ID NO 11619 8061198 85.71 SEQ ID NO 11667 8139271 75.00

SEQ ID NO 11620 8087595 75.00 SEQ ID NO 11668 8140885 93.33

SEQ ID NO 11621 8089045 100.00 SEQ ID NO 11669 8143097 93.33

SEQ ID NO 11622 8090014 85.71 SEQ ID NO 11670 8145630 80.00

SEQ ID NO 11623 8090130 85.71 SEQ ID NO 11671 8154484 83.33

SEQ ID NO 11624 8091879 83.33 SEQ ID NO 11672 8158764 93.33

SEQ ID NO 11625 8091965 85.71 SEQ ID NO 11673 8165376 75.00

SEQ ID NO 11626 8092196 85.71 SEQ ID NO 11674 8165737 93.33

SEQ ID NO 11627 8093745 85.71 SEQ ID NO 11675 8166892 85.71

SEQ ID NO 11628 8094040 84.62 SEQ ID NO 11676 8167366 85.71

SEQ ID NO 11629 8094292 80.00 SEQ ID NO 11677 8167392 70.00

SEQ ID NO 11630 8094417 86.67 SEQ ID NO 11678 8167429 85.71

SEQ ID NO 11631 8094563 85.71 SEQ ID NO 11679 8168089 85.71

SEQ ID NO 11632 8095200 75.00 SEQ ID NO 11680 8174974 86.67

SEQ ID NO 11633 8095206 80.00 SEQ ID NO 11681 8175986 75.00

SEQ ID NO 11634 8095251 80.00 SEQ ID NO 11682 8178212 85.71

SEQ ID NO 11635 8095347 80.00 SEQ ID NO 11683 8179746 85.71

SEQ ID NO 11636 8096603 86.67 SEQ ID NO 11684 8180089 85.71

SEQ ID NO 11637 8096625 86.67 SEQ ID NO 11685 8180388 85.71

SEQ ID NO 11638 8097278 75.00 SEQ ID NO 11686 8181115 85.71

SEQ ID NO 11639 8097412 85.71 SEQ ID NO 11687 8181306 93.33

SEQ ID NO 11640 8097937 93.33 SEQ ID NO 11688 8184367 80.00

SEQ ID NO 11641 8105292 87.50 SEQ ID NO 11689 8185101 93.33

SEQ ID NO 11642 8110446 85.71 SEQ ID NO 11690 8185171 88.89

SEQ ID NO 11643 8112571 85.71 SEQ ID NO 11691 8185193 93.33

SEQ ID NO 11644 8116215 85.71 SEQ ID NO 11692 8186834 85.71

SEQ ID NO 11645 8117233 80.00 SEQ ID NO 11693 8187348 85.71

SEQ ID NO 11646 8121575 75.00 SEQ ID NO 11694 8195150 80.00

SEQ ID NO 11647 8124321 80.00 SEQ ID NO 11695 8219550 83.33

SEQ ID NO 11648 8124809 85.71 SEQ ID NO 11696 8223265 87.50

SEQ ID NO 11649 8125802 85.71 SEQ ID NO 11697 8224528 83.33

SEQ ID NO 11650 8126420 85.71 SEQ ID NO 11698 8224549 81.82

SEQ ID NO 11651 8126756 85.71 SEQ ID NO 11699 8224589 81.82

SEQ ID NO 11652 8135206 84.62 SEQ ID NO 11700 8224711 85.71

SEQ ID NO 11653 8135352 75.00 SEQ ID NO 11701 8224919 85.71

SEQ ID NO 11654 8135671 86.67 SEQ ID NO 11702 8224990 86.67 SEQ ID NO 11703 8228170 75.00 SEQ ID NO 11751 8259441 92.86

SEQ ID NO 11704 8229735 85.71 SEQ ID NO 11752 8259490 87.50

SEQ ID NO 11705 8230878 100.00 SEQ ID NO 11753 8261249 100.00

SEQ ID NO 11706 8231062 85.71 SEQ ID NO 11754 8261258 100.00

SEQ ID NO 11707 8231071 85.71 SEQ ID NO 11755 8261283 100.00

SEQ ID NO 11708 8231440 85.71 SEQ ID NO 11756 8261940 100.00

SEQ ID NO 11709 8233255 85.71 SEQ ID NO 11757 8261977 100.00

SEQ ID NO 11710 8244925 85.71 SEQ ID NO 11758 8262061 75.00

SEQ ID NO 11711 8247162 80.00 SEQ ID NO 11759 8262226 92.31

SEQ ID NO 11712 8247371 86.67 SEQ ID NO 11760 8262244 92.86

SEQ ID NO 11713 8247478 85.71 SEQ ID NO 11761 8262423 92.86

SEQ ID NO 11714 8247524 86.67 SEQ ID NO 11762 8264956 75.00

SEQ ID NO 11715 8247589 84.62 SEQ ID NO 11763 8264994 83.33

SEQ ID NO 11716 8247922 93.33 SEQ ID NO 11764 8265004 83.33

SEQ ID NO 11717 8248370 85.71 SEQ ID NO 11765 8265007 75.00

SEQ ID NO 11718 8249450 86.67 SEQ ID NO 11766 8265016 92.31

SEQ ID NO 11719 8249459 86.67 SEQ ID NO 11767 8265056 85.71

SEQ ID NO 11720 8249512 86.67 SEQ ID NO 11768 8265159 93.33

SEQ ID NO 11721 8251287 83.33 SEQ ID NO 11769 8265184 80.00

SEQ ID NO 11722 8252174 93.33 SEQ ID NO 11770 8265198 93.33

SEQ ID NO 11723 8253916 91.67 SEQ ID NO 11771 8265208 75.00

SEQ ID NO 11724 8253933 92.31 SEQ ID NO 11772 8273847 80.00

SEQ ID NO 11725 8253964 88.89 SEQ ID NO 11773 8274030 93.33

SEQ ID NO 11726 8254002 93.33 SEQ ID NO 11774 8274120 93.33

SEQ ID NO 11727 8254006 90.00 SEQ ID NO 11775 8274413 75.00

SEQ ID NO 11728 8254063 86.67 SEQ ID NO 11776 8274456 100.00

SEQ ID NO 11729 8254148 93.33 SEQ ID NO 11777 8274697 90.91

SEQ ID NO 11730 8254165 93.33 SEQ ID NO 11778 8274787 93.33

SEQ ID NO 11731 8254260 93.33 SEQ ID NO 11779 8274855 93.33

SEQ ID NO 11732 8254267 93.33 SEQ ID NO 11780 8274962 93.33

SEQ ID NO 11733 8254407 93.33 SEQ ID NO 11781 8274998 75.00

SEQ ID NO 11734 8254428 93.33 SEQ ID NO 11782 8275148 93.33

SEQ ID NO 11735 8254692 93.33 SEQ ID NO 11783 8275392 92.31

SEQ ID NO 11736 8255313 93.33 SEQ ID NO 11784 8275436 93.33

SEQ ID NO 11737 8255652 93.33 SEQ ID NO 11785 8277234 86.67

SEQ ID NO 11738 8257064 93.33 SEQ ID NO 11786 8277267 84.62

SEQ ID NO 11739 8257756 86.67 SEQ ID NO 11787 8282377 85.71

SEQ ID NO 11740 8258860 93.33 SEQ ID NO 11788 8282398 85.71

SEQ ID NO 11741 8258873 92.31 SEQ ID NO 11789 8282651 85.71

SEQ ID NO 11742 8258978 92.86 SEQ ID NO 11790 8282719 80.00

SEQ ID NO 11743 8259034 75.00 SEQ ID NO 11791 8284656 100.00

SEQ ID NO 11744 8259086 85.71 SEQ ID NO 11792 8284975 85.71

SEQ ID NO 11745 8259088 75.00 SEQ ID NO 11793 8285342 93.33

SEQ ID NO 11746 8259128 93.33 SEQ ID NO 11794 8285574 86.67

SEQ ID NO 11747 8259270 93.33 SEQ ID NO 11795 8285895 84.62

SEQ ID NO 11748 8259353 92.86 SEQ ID NO 11796 8286021 85.71

SEQ ID NO 11749 8259395 70.00 SEQ ID NO 11797 8286932 93.33

SEQ ID NO 11750 8259424 93.33 SEQ ID NO 11798 8286948 83.33 SEQ ID NO 11799 8286972 84.62 SEQ ID NO 11847 8328521 80.00

SEQ ID NO 11800 8286987 92.86 SEQ ID NO 11848 8328698 75.00

SEQ ID NO 11801 8287146 86.67 SEQ ID NO 11849 8328803 75.00

SEQ ID NO 11802 8287403 81.82 SEQ ID NO 11850 8328815 100.00

SEQ ID NO 11803 8287465 83.33 SEQ ID NO 11851 8328833 100.00

SEQ ID NO 11804 8287471 85.71 SEQ ID NO 11852 8328917 100.00

SEQ ID NO 11805 8289982 93.33 SEQ ID NO 11853 8329325 100.00

SEQ ID NO 11806 8292453 93.33 SEQ ID NO 11854 8329456 71.43

SEQ ID NO 11807 8292657 90.00 SEQ ID NO 11855 8329661 80.00

SEQ ID NO 11808 8292682 92.31 SEQ ID NO 11856 8329895 80.00

SEQ ID NO 11809 8292947 100.00 SEQ ID NO 11857 8329936 71.43

SEQ ID NO 11810 8293083 85.71 SEQ ID NO 11858 8330116 75.00

SEQ ID NO 11811 8293085 90.91 SEQ ID NO 11859 8330120 80.00

SEQ ID NO 11812 8293120 80.00 SEQ ID NO 11860 8330149 100.00

SEQ ID NO 11813 8294933 76.92 SEQ ID NO 11861 8330583 75.00

SEQ ID NO 11814 8295098 88.89 SEQ ID NO 11862 8331364 71.43

SEQ ID NO 11815 8295321 93.33 SEQ ID NO 11863 8331366 71.43

SEQ ID NO 11816 8295442 75.00 SEQ ID NO 11864 8331566 85.71

SEQ ID NO 11817 8295461 91.67 SEQ ID NO 11865 8332132 85.71

SEQ ID NO 11818 8295779 85.71 SEQ ID NO 11866 8336831 86.67

SEQ ID NO 11819 8295938 80.00 SEQ ID NO 11867 8337484 85.71

SEQ ID NO 11820 8296094 93.33 SEQ ID NO 11868 8337491 85.71

SEQ ID NO 11821 8299529 85.71 SEQ ID NO 11869 8337582 86.67

SEQ ID NO 11822 8300666 86.67 SEQ ID NO 11870 8337720 86.67

SEQ ID NO 11823 8301073 86.67 SEQ ID NO 11871 8337735 86.67

SEQ ID NO 11824 8301729 86.67 SEQ ID NO 11872 8340234 80.00

SEQ ID NO 11825 8301904 100.00 SEQ ID NO 11873 8341566 80.00

SEQ ID NO 11826 8302322 72.73 SEQ ID NO 11874 8341591 80.00

SEQ ID NO 11827 8302442 83.33 SEQ ID NO 11875 8341701 80.00

SEQ ID NO 11828 8302559 88.89 SEQ ID NO 11876 8351532 86.67

SEQ ID NO 11829 8302994 88.89 SEQ ID NO 11877 8354930 80.00

SEQ ID NO 11830 8304888 86.67 SEQ ID NO 11878 8355281 78.57

SEQ ID NO 11831 8305166 86.67 SEQ ID NO 11879 8355331 75.00

SEQ ID NO 11832 8305451 76.92 SEQ ID NO 11880 8360170 80.00

SEQ ID NO 11833 8305483 85.71 SEQ ID NO 11881 8361101 85.71

SEQ ID NO 11834 8309893 86.67 SEQ ID NO 11882 8361830 80.00

SEQ ID NO 11835 8310014 91.67 SEQ ID NO 11883 8361860 85.71

SEQ ID NO 11836 8310375 93.33 SEQ ID NO 11884 8362020 86.67

SEQ ID NO 11837 8311520 80.00 SEQ ID NO 11885 8368005 85.71

SEQ ID NO 11838 8311836 86.67 SEQ ID NO 11886 8368421 85.71

SEQ ID NO 11839 8318830 80.00 SEQ ID NO 11887 8368655 92.86

SEQ ID NO 11840 8326464 83.33 SEQ ID NO 11888 8369007 85.71

SEQ ID NO 11841 8327402 75.00 SEQ ID NO 11889 8370537 84.62

SEQ ID NO 11842 8327620 87.50 SEQ ID NO 11890 8376598 86.67

SEQ ID NO 11843 8327658 83.33 SEQ ID NO 11891 8409051 80.00

SEQ ID NO 11844 8327911 100.00 SEQ ID NO 11892 8410733 85.71

SEQ ID NO 11845 8327989 78.57 SEQ ID NO 11893 8416326 91.67

SEQ ID NO 11846 8328087 70.00 SEQ ID NO 11894 8416409 90.00 SEQ ID NO 11895 8416473 92.31 SEQ ID NO 11943 8434118 85.71

SEQ ID NO 11896 8416557 100.00 SEQ ID NO 11944 8434145 88.89

SEQ ID NO 11897 8416667 93.33 SEQ ID NO 11945 8434174 92.31

SEQ ID NO 11898 8416700 93.33 SEQ ID NO 11946 8434223 92.86

SEQ ID NO 11899 8416807 92.86 SEQ ID NO 11947 8434261 93.33

SEQ ID NO 11900 8416843 86.67 SEQ ID NO 11948 8434276 93.33

SEQ ID NO 11901 8416941 93.33 SEQ ID NO 11949 8434287 83.33

SEQ ID NO 11902 8416961 93.33 SEQ ID NO 11950 8434508 93.33

SEQ ID NO 11903 8416973 93.33 SEQ ID NO 11951 8434525 92.86

SEQ ID NO 11904 8416982 93.33 SEQ ID NO 11952 8434540 88.89

SEQ ID NO 11905 8417111 92.86 SEQ ID NO 11953 8434554 90.00

SEQ ID NO 11906 8417179 90.00 SEQ ID NO 11954 8434606 92.86

SEQ ID NO 11907 8417215 91.67 SEQ ID NO 11955 8434632 80.00

SEQ ID NO 11908 8417506 85.71 SEQ ID NO 11956 8434639 100.00

SEQ ID NO 11909 8417592 100.00 SEQ ID NO 11957 8434661 87.50

SEQ ID NO 11910 8417802 92.86 SEQ ID NO 11958 8434674 75.00

SEQ ID NO 11911 8417898 92.86 SEQ ID NO 11959 8434680 80.00

SEQ ID NO 11912 8417930 92.31 SEQ ID NO 11960 8434711 85.71

SEQ ID NO 11913 8417940 91.67 SEQ ID NO 11961 8434720 75.00

SEQ ID NO 11914 8417972 100.00 SEQ ID NO 11962 8434782 75.00

SEQ ID NO 11915 8417991 91.67 SEQ ID NO 11963 8434962 100.00

SEQ ID NO 11916 8418012 92.31 SEQ ID NO 11964 8434977 80.00

SEQ ID NO 11917 8419163 85.71 SEQ ID NO 11965 8434993 75.00

SEQ ID NO 11918 8419206 100.00 SEQ ID NO 11966 8436165 92.86

SEQ ID NO 11919 8419444 100.00 SEQ ID NO 11967 8436196 92.86

SEQ ID NO 11920 8419483 92.31 SEQ ID NO 11968 8436340 92.86

SEQ ID NO 11921 8419794 90.91 SEQ ID NO 11969 8436353 92.86

SEQ ID NO 11922 8419815 93.33 SEQ ID NO 11970 8436444 91.67

SEQ ID NO 11923 8419950 93.33 SEQ ID NO 11971 8436489 90.91

SEQ ID NO 11924 8419966 93.33 SEQ ID NO 11972 8436829 90.00

SEQ ID NO 11925 8420073 86.67 SEQ ID NO 11973 8436870 81.82

SEQ ID NO 11926 8420129 93.33 SEQ ID NO 11974 8436913 77.78

SEQ ID NO 11927 8420133 93.33 SEQ ID NO 11975 8436926 77.78

SEQ ID NO 11928 8420375 90.00 SEQ ID NO 11976 8436959 100.00

SEQ ID NO 11929 8422138 80.00 SEQ ID NO 11977 8436974 88.89

SEQ ID NO 11930 8422240 85.71 SEQ ID NO 11978 8437010 87.50

SEQ ID NO 11931 8423531 76.92 SEQ ID NO 11979 8437355 80.00

SEQ ID NO 11932 8427667 86.67 SEQ ID NO 11980 8437374 83.33

SEQ ID NO 11933 8428337 86.67 SEQ ID NO 11981 8437386 87.50

SEQ ID NO 11934 8429750 86.67 SEQ ID NO 11982 8437390 100.00

SEQ ID NO 11935 8429815 100.00 SEQ ID NO 11983 8437427 100.00

SEQ ID NO 11936 8430280 86.67 SEQ ID NO 11984 8437472 85.71

SEQ ID NO 11937 8430357 86.67 SEQ ID NO 11985 8437497 87.50

SEQ ID NO 11938 8431064 86.67 SEQ ID NO 11986 8437541 78.57

SEQ ID NO 11939 8433665 85.71 SEQ ID NO 11987 8437785 87.50

SEQ ID NO 11940 8433916 93.33 SEQ ID NO 11988 8437801 75.00

SEQ ID NO 11941 8433920 93.33 SEQ ID NO 11989 8437957 100.00

SEQ ID NO 11942 8434064 93.33 SEQ ID NO 11990 8438248 72.73 SEQ ID NO 11991 8440908 75.00 SEQ ID NO 12039 8451905 92.31

SEQ ID NO 11992 8441025 75.00 SEQ ID NO 12040 8451970 86.67

SEQ ID NO 11993 8441519 90.91 SEQ ID NO 12041 8451999 93.33

SEQ ID NO 11994 8441733 100.00 SEQ ID NO 12042 8452043 87.50

SEQ ID NO 11995 8441931 100.00 SEQ ID NO 12043 8452149 83.33

SEQ ID NO 11996 8441961 100.00 SEQ ID NO 12044 8452219 92.31

SEQ ID NO 11997 8442408 100.00 SEQ ID NO 12045 8452240 85.71

SEQ ID NO 11998 8442553 100.00 SEQ ID NO 12046 8452403 100.00

SEQ ID NO 11999 8446257 100.00 SEQ ID NO 12047 8452434 80.00

SEQ ID NO 12000 8446310 88.89 SEQ ID NO 12048 8452480 71.43

SEQ ID NO 12001 8446365 75.00 SEQ ID NO 12049 8452508 90.00

SEQ ID NO 12002 8446408 83.33 SEQ ID NO 12050 8452543 88.89

SEQ ID NO 12003 8446425 100.00 SEQ ID NO 12051 8452558 100.00

SEQ ID NO 12004 8446608 100.00 SEQ ID NO 12052 8452631 100.00

SEQ ID NO 12005 8446682 100.00 SEQ ID NO 12053 8452674 87.50

SEQ ID NO 12006 8446710 75.00 SEQ ID NO 12054 8452709 93.33

SEQ ID NO 12007 8446815 90.00 SEQ ID NO 12055 8452750 92.86

SEQ ID NO 12008 8448489 75.00 SEQ ID NO 12056 8452762 86.67

SEQ ID NO 12009 8448585 80.00 SEQ ID NO 12057 8452774 100.00

SEQ ID NO 12010 8448596 91.67 SEQ ID NO 12058 8452836 93.33

SEQ ID NO 12011 8448608 83.33 SEQ ID NO 12059 8452845 86.67

SEQ ID NO 12012 8448637 92.31 SEQ ID NO 12060 8452867 100.00

SEQ ID NO 12013 8448653 92.31 SEQ ID NO 12061 8452896 90.91

SEQ ID NO 12014 8448955 100.00 SEQ ID NO 12062 8452936 91.67

SEQ ID NO 12015 8448971 85.71 SEQ ID NO 12063 8452982 90.00

SEQ ID NO 12016 8449260 92.86 SEQ ID NO 12064 8453015 85.71

SEQ ID NO 12017 8450349 88.89 SEQ ID NO 12065 8453172 100.00

SEQ ID NO 12018 8450406 100.00 SEQ ID NO 12066 8453198 100.00

SEQ ID NO 12019 8450410 88.89 SEQ ID NO 12067 8453327 100.00

SEQ ID NO 12020 8450438 90.91 SEQ ID NO 12068 8453420 100.00

SEQ ID NO 12021 8450441 83.33 SEQ ID NO 12069 8453445 100.00

SEQ ID NO 12022 8450488 87.50 SEQ ID NO 12070 8453560 92.86

SEQ ID NO 12023 8450635 93.33 SEQ ID NO 12071 8453563 88.89

SEQ ID NO 12024 8450883 88.89 SEQ ID NO 12072 8453633 100.00

SEQ ID NO 12025 8451183 75.00 SEQ ID NO 12073 8453646 100.00

SEQ ID NO 12026 8451300 75.00 SEQ ID NO 12074 8453683 100.00

SEQ ID NO 12027 8451401 91.67 SEQ ID NO 12075 8453705 100.00

SEQ ID NO 12028 8451406 83.33 SEQ ID NO 12076 8453769 75.00

SEQ ID NO 12029 8451442 88.89 SEQ ID NO 12077 8453937 92.31

SEQ ID NO 12030 8451514 92.86 SEQ ID NO 12078 8454002 88.89

SEQ ID NO 12031 8451541 92.86 SEQ ID NO 12079 8454012 80.00

SEQ ID NO 12032 8451548 100.00 SEQ ID NO 12080 8454029 92.86

SEQ ID NO 12033 8451583 86.67 SEQ ID NO 12081 8454044 92.31

SEQ ID NO 12034 8451635 86.67 SEQ ID NO 12082 8454054 92.86

SEQ ID NO 12035 8451723 85.71 SEQ ID NO 12083 8454067 86.67

SEQ ID NO 12036 8451752 83.33 SEQ ID NO 12084 8454071 90.91

SEQ ID NO 12037 8451777 85.71 SEQ ID NO 12085 8454109 85.71

SEQ ID NO 12038 8451862 88.89 SEQ ID NO 12086 8454132 84.62 SEQ ID NO 12087 8454137 93.33 SEQ ID NO 12135 8475286 100.00

SEQ ID NO 12088 8454197 93.33 SEQ ID NO 12136 8476564 87.50

SEQ ID NO 12089 8454198 90.91 SEQ ID NO 12137 8478579 91.67

SEQ ID NO 12090 8454265 92.31 SEQ ID NO 12138 8479240 100.00

SEQ ID NO 12091 8454295 85.71 SEQ ID NO 12139 8479294 90.91

SEQ ID NO 12092 8454366 92.86 SEQ ID NO 12140 8479301 91.67

SEQ ID NO 12093 8456977 90.91 SEQ ID NO 12141 8480622 92.86

SEQ ID NO 12094 8457444 91.67 SEQ ID NO 12142 8482178 80.00

SEQ ID NO 12095 8457660 87.50 SEQ ID NO 12143 8482182 90.00

SEQ ID NO 12096 8457681 88.89 SEQ ID NO 12144 8482585 93.33

SEQ ID NO 12097 8457816 93.33 SEQ ID NO 12145 8482775 91.67

SEQ ID NO 12098 8457899 84.62 SEQ ID NO 12146 8483825 91.67

SEQ ID NO 12099 8457951 92.31 SEQ ID NO 12147 8484079 91.67

SEQ ID NO 12100 8458946 83.33 SEQ ID NO 12148 8484754 86.67

SEQ ID NO 12101 8459006 85.71 SEQ ID NO 12149 8484771 86.67

SEQ ID NO 12102 8459486 100.00 SEQ ID NO 12150 8484800 92.86

SEQ ID NO 12103 8459538 86.67 SEQ ID NO 12151 8485232 86.67

SEQ ID NO 12104 8459559 92.86 SEQ ID NO 12152 8485330 71.43

SEQ ID NO 12105 8459597 80.00 SEQ ID NO 12153 8485840 80.00

SEQ ID NO 12106 8459658 91.67 SEQ ID NO 12154 8485923 75.00

SEQ ID NO 12107 8459673 90.00 SEQ ID NO 12155 8487809 80.00

SEQ ID NO 12108 8459712 93.33 SEQ ID NO 12156 8487836 86.67

SEQ ID NO 12109 8459922 100.00 SEQ ID NO 12157 8488887 84.62

SEQ ID NO 12110 8460080 90.00 SEQ ID NO 12158 8489634 86.67

SEQ ID NO 12111 8460161 92.86 SEQ ID NO 12159 8490056 100.00

SEQ ID NO 12112 8460201 90.91 SEQ ID NO 12160 8491192 100.00

SEQ ID NO 12113 8460234 100.00 SEQ ID NO 12161 8491602 100.00

SEQ ID NO 12114 8460256 100.00 SEQ ID NO 12162 8491850 83.33

SEQ ID NO 12115 8460298 91.67 SEQ ID NO 12163 8492001 100.00

SEQ ID NO 12116 8461024 90.91 SEQ ID NO 12164 8492007 75.00

SEQ ID NO 12117 8461486 90.00 SEQ ID NO 12165 8493062 92.86

SEQ ID NO 12118 8461620 84.62 SEQ ID NO 12166 8493182 92.86

SEQ ID NO 12119 8461797 90.00 SEQ ID NO 12167 8493241 86.67

SEQ ID NO 12120 8461804 92.31 SEQ ID NO 12168 8494397 93.33

SEQ ID NO 12121 8462013 88.89 SEQ ID NO 12169 8495478 92.86

SEQ ID NO 12122 8462113 100.00 SEQ ID NO 12170 8495798 93.33

SEQ ID NO 12123 8462216 92.86 SEQ ID NO 12171 8496095 86.67

SEQ ID NO 12124 8462483 92.86 SEQ ID NO 12172 8496120 93.33

SEQ ID NO 12125 8462636 86.67 SEQ ID NO 12173 8496502 100.00

SEQ ID NO 12126 8462679 92.31 SEQ ID NO 12174 8497378 91.67

SEQ ID NO 12127 8462750 92.86 SEQ ID NO 12175 8497854 91.67

SEQ ID NO 12128 8462849 100.00 SEQ ID NO 12176 8500609 91.67

SEQ ID NO 12129 8463394 92.86 SEQ ID NO 12177 8502358 100.00

SEQ ID NO 12130 8464115 91.67 SEQ ID NO 12178 8503015 92.86

SEQ ID NO 12131 8464363 85.71 SEQ ID NO 12179 8503918 90.91

SEQ ID NO 12132 8468344 80.00 SEQ ID NO 12180 8503979 93.33

SEQ ID NO 12133 8468401 100.00 SEQ ID NO 12181 8506877 100.00

SEQ ID NO 12134 8471348 90.91 SEQ ID NO 12182 8506887 92.86 SEQ ID NO 12183 8507319 91.67 SEQ ID NO 12231 8517678 93.33

SEQ ID NO 12184 8508086 90.91 SEQ ID NO 12232 8517757 93.33

SEQ ID NO 12185 8508207 92.86 SEQ ID NO 12233 8517914 93.33

SEQ ID NO 12186 8508373 88.89 SEQ ID NO 12234 8517953 93.33

SEQ ID NO 12187 8508472 92.31 SEQ ID NO 12235 8517965 93.33

SEQ ID NO 12188 8508657 100.00 SEQ ID NO 12236 8517969 92.86

SEQ ID NO 12189 8508822 92.86 SEQ ID NO 12237 8517987 93.33

SEQ ID NO 12190 8508853 84.62 SEQ ID NO 12238 8517995 92.86

SEQ ID NO 12191 8508996 92.31 SEQ ID NO 12239 8518078 86.67

SEQ ID NO 12192 8509179 92.31 SEQ ID NO 12240 8518087 93.33

SEQ ID NO 12193 8509231 90.00 SEQ ID NO 12241 8518190 92.31

SEQ ID NO 12194 8509284 92.86 SEQ ID NO 12242 8518201 92.86

SEQ ID NO 12195 8509445 93.33 SEQ ID NO 12243 8518220 92.86

SEQ ID NO 12196 8509672 88.89 SEQ ID NO 12244 8518275 93.33

SEQ ID NO 12197 8509878 92.86 SEQ ID NO 12245 8518284 92.86

SEQ ID NO 12198 8511932 100.00 SEQ ID NO 12246 8518309 80.00

SEQ ID NO 12199 8512055 75.00 SEQ ID NO 12247 8518317 93.33

SEQ ID NO 12200 8512304 90.91 SEQ ID NO 12248 8518406 92.86

SEQ ID NO 12201 8512318 92.31 SEQ ID NO 12249 8518473 93.33

SEQ ID NO 12202 8512496 81.82 SEQ ID NO 12250 8518518 92.86

SEQ ID NO 12203 8512850 93.33 SEQ ID NO 12251 8518879 100.00

SEQ ID NO 12204 8513622 92.86 SEQ ID NO 12252 8519082 92.86

SEQ ID NO 12205 8514011 86.67 SEQ ID NO 12253 8519121 92.86

SEQ ID NO 12206 8514169 92.86 SEQ ID NO 12254 8519130 92.86

SEQ ID NO 12207 8514304 92.86 SEQ ID NO 12255 8519150 92.86

SEQ ID NO 12208 8514418 100.00 SEQ ID NO 12256 8519179 92.86

SEQ ID NO 12209 8514498 86.67 SEQ ID NO 12257 8519200 92.31

SEQ ID NO 12210 8514531 92.31 SEQ ID NO 12258 8519291 86.67

SEQ ID NO 12211 8514702 100.00 SEQ ID NO 12259 8519340 80.00

SEQ ID NO 12212 8514753 92.31 SEQ ID NO 12260 8519426 92.31

SEQ ID NO 12213 8514862 91.67 SEQ ID NO 12261 8523165 86.67

SEQ ID NO 12214 8515854 93.33 SEQ ID NO 12262 8523515 86.67

SEQ ID NO 12215 8515925 83.33 SEQ ID NO 12263 8523519 86.67

SEQ ID NO 12216 8516240 100.00 SEQ ID NO 12264 8523788 85.71

SEQ ID NO 12217 8516307 90.00 SEQ ID NO 12265 8524088 92.31

SEQ ID NO 12218 8516508 100.00 SEQ ID NO 12266 8528760 75.00

SEQ ID NO 12219 8516819 93.33 SEQ ID NO 12267 8529110 85.71

SEQ ID NO 12220 8516878 92.86 SEQ ID NO 12268 8529127 80.00

SEQ ID NO 12221 8516901 90.91 SEQ ID NO 12269 8530270 86.67

SEQ ID NO 12222 8516945 93.33 SEQ ID NO 12270 8530293 86.67

SEQ ID NO 12223 8516994 93.33 SEQ ID NO 12271 8530328 86.67

SEQ ID NO 12224 8517087 92.86 SEQ ID NO 12272 8530356 86.67

SEQ ID NO 12225 8517167 93.33 SEQ ID NO 12273 8531551 92.86

SEQ ID NO 12226 8517461 92.86 SEQ ID NO 12274 8531583 92.86

SEQ ID NO 12227 8517515 93.33 SEQ ID NO 12275 8531610 92.86

SEQ ID NO 12228 8517564 92.31 SEQ ID NO 12276 8531621 92.86

SEQ ID NO 12229 8517573 93.33 SEQ ID NO 12277 8531635 92.86

SEQ ID NO 12230 8517663 93.33 SEQ ID NO 12278 8531644 92.31 SEQ ID NO 12279 8531648 92.86 SEQ ID NO 12327 8551896 87.50

SEQ ID NO 12280 8531667 90.91 SEQ ID NO 12328 8552152 100.00

SEQ ID NO 12281 8531673 92.86 SEQ ID NO 12329 8552230 92.86

SEQ ID NO 12282 8531720 92.86 SEQ ID NO 12330 8552251 100.00

SEQ ID NO 12283 8531904 90.00 SEQ ID NO 12331 8552260 100.00

SEQ ID NO 12284 8531997 92.86 SEQ ID NO 12332 8552287 92.31

SEQ ID NO 12285 8532159 86.67 SEQ ID NO 12333 8552312 87.50

SEQ ID NO 12286 8532201 86.67 SEQ ID NO 12334 8552338 92.86

SEQ ID NO 12287 8532269 92.86 SEQ ID NO 12335 8552383 100.00

SEQ ID NO 12288 8532446 92.86 SEQ ID NO 12336 8552516 93.33

SEQ ID NO 12289 8532724 92.86 SEQ ID NO 12337 8552519 93.33

SEQ ID NO 12290 8532802 92.31 SEQ ID NO 12338 8552772 92.86

SEQ ID NO 12291 8532866 85.71 SEQ ID NO 12339 8552799 92.86

SEQ ID NO 12292 8532946 100.00 SEQ ID NO 12340 8552879 92.86

SEQ ID NO 12293 8532985 100.00 SEQ ID NO 12341 8552907 92.86

SEQ ID NO 12294 8533194 75.00 SEQ ID NO 12342 8552998 92.86

SEQ ID NO 12295 8533208 100.00 SEQ ID NO 12343 8553006 92.86

SEQ ID NO 12296 8533247 88.89 SEQ ID NO 12344 8553113 92.86

SEQ ID NO 12297 8533285 88.89 SEQ ID NO 12345 8553132 92.86

SEQ ID NO 12298 8533621 71.43 SEQ ID NO 12346 8553160 92.86

SEQ ID NO 12299 8533626 77.78 SEQ ID NO 12347 8554172 93.33

SEQ ID NO 12300 8533651 90.91 SEQ ID NO 12348 8554196 91.67

SEQ ID NO 12301 8533772 93.33 SEQ ID NO 12349 8554242 93.33

SEQ ID NO 12302 8533870 92.86 SEQ ID NO 12350 8554351 93.33

SEQ ID NO 12303 8533998 86.67 SEQ ID NO 12351 8554515 92.86

SEQ ID NO 12304 8534078 93.33 SEQ ID NO 12352 8554555 92.86

SEQ ID NO 12305 8534177 93.33 SEQ ID NO 12353 8554740 85.71

SEQ ID NO 12306 8534255 92.86 SEQ ID NO 12354 8555353 92.86

SEQ ID NO 12307 8534364 93.33 SEQ ID NO 12355 8555905 93.33

SEQ ID NO 12308 8534416 93.33 SEQ ID NO 12356 8556057 92.86

SEQ ID NO 12309 8534420 93.33 SEQ ID NO 12357 8556370 92.86

SEQ ID NO 12310 8534438 93.33 SEQ ID NO 12358 8556415 93.33

SEQ ID NO 12311 8534500 93.33 SEQ ID NO 12359 8556431 92.31

SEQ ID NO 12312 8537013 93.33 SEQ ID NO 12360 8556462 92.86

SEQ ID NO 12313 8537042 93.33 SEQ ID NO 12361 8556474 93.33

SEQ ID NO 12314 8537049 93.33 SEQ ID NO 12362 8556556 92.86

SEQ ID NO 12315 8537062 93.33 SEQ ID NO 12363 8556580 92.86

SEQ ID NO 12316 8537138 93.33 SEQ ID NO 12364 8556603 92.31

SEQ ID NO 12317 8537320 90.00 SEQ ID NO 12365 8556655 85.71

SEQ ID NO 12318 8537357 100.00 SEQ ID NO 12366 8556927 85.71

SEQ ID NO 12319 8537359 100.00 SEQ ID NO 12367 8556987 86.67

SEQ ID NO 12320 8540024 85.71 SEQ ID NO 12368 8557003 86.67

SEQ ID NO 12321 8540310 100.00 SEQ ID NO 12369 8557295 93.33

SEQ ID NO 12322 8540696 87.50 SEQ ID NO 12370 8557301 93.33

SEQ ID NO 12323 8540891 83.33 SEQ ID NO 12371 8557313 92.31

SEQ ID NO 12324 8541031 76.92 SEQ ID NO 12372 8557355 92.86

SEQ ID NO 12325 8541341 86.67 SEQ ID NO 12373 8557406 85.71

SEQ ID NO 12326 8551060 100.00 SEQ ID NO 12374 8557485 93.33 SEQ ID NO 12375 8592473 100.00 SEQ ID NO 12423 8928991 80.00

SEQ ID NO 12376 8592640 75.00 SEQ ID NO 12424 8931759 100.00

SEQ ID NO 12377 8592781 80.00 SEQ ID NO 12425 8939719 100.00

SEQ ID NO 12378 8657492 100.00 SEQ ID NO 12426 8962295 100.00

SEQ ID NO 12379 8669229 85.71 SEQ ID NO 12427 8966598 93.33

SEQ ID NO 12380 8669712 100.00 SEQ ID NO 12428 8968391 93.33

SEQ ID NO 12381 8670054 92.31 SEQ ID NO 12429 8974198 78.57

SEQ ID NO 12382 8670217 85.71 SEQ ID NO 12430 8975269 93.33

SEQ ID NO 12383 8670234 75.00 SEQ ID NO 12431 8975276 93.33

SEQ ID NO 12384 8670393 100.00 SEQ ID NO 12432 8975645 76.92

SEQ ID NO 12385 8670530 86.67 SEQ ID NO 12433 8977128 93.33

SEQ ID NO 12386 8672320 85.71 SEQ ID NO 12434 8984917 80.00

SEQ ID NO 12387 8685362 86.67 SEQ ID NO 12435 8986195 93.33

SEQ ID NO 12388 8685602 86.67 SEQ ID NO 12436 8986659 85.71

SEQ ID NO 12389 8695750 85.71 SEQ ID NO 12437 8988150 93.33

SEQ ID NO 12390 8703945 100.00 SEQ ID NO 12438 8990756 93.33

SEQ ID NO 12391 8737470 100.00 SEQ ID NO 12439 8996342 91.67

SEQ ID NO 12392 8738770 76.92 SEQ ID NO 12440 8996949 86.67

SEQ ID NO 12393 8739009 85.71 SEQ ID NO 12441 8996979 85.71

SEQ ID NO 12394 8740045 100.00 SEQ ID NO 12442 8997136 86.67

SEQ ID NO 12395 8756298 86.67 SEQ ID NO 12443 8998174 86.67

SEQ ID NO 12396 8759977 91.67 SEQ ID NO 12444 9000908 86.67

SEQ ID NO 12397 8761565 87.50 SEQ ID NO 12445 9002687 85.71

SEQ ID NO 12398 8772339 100.00 SEQ ID NO 12446 9003097 70.00

SEQ ID NO 12399 8777523 83.33 SEQ ID NO 12447 9005240 86.67

SEQ ID NO 12400 8791275 88.89 SEQ ID NO 12448 9010971 85.71

SEQ ID NO 12401 8793963 86.67 SEQ ID NO 12449 9016849 85.71

SEQ ID NO 12402 8795661 83.33 SEQ ID NO 12450 9018598 86.67

SEQ ID NO 12403 8797987 100.00 SEQ ID NO 12451 9021366 86.67

SEQ ID NO 12404 8806209 83.33 SEQ ID NO 12452 9022030 70.00

SEQ ID NO 12405 8820335 86.67 SEQ ID NO 12453 9027683 85.71

SEQ ID NO 12406 8820894 70.00 SEQ ID NO 12454 9028007 75.00

SEQ ID NO 12407 8824077 78.57 SEQ ID NO 12455 9028237 87.50

SEQ ID NO 12408 8826334 85.71 SEQ ID NO 12456 9028371 75.00

SEQ ID NO 12409 8834047 86.67 SEQ ID NO 12457 9029507 80.00

SEQ ID NO 12410 8841132 100.00 SEQ ID NO 12458 9043891 72.73

SEQ ID NO 12411 8851780 100.00 SEQ ID NO 12459 9044699 86.67

SEQ ID NO 12412 8852349 85.71 SEQ ID NO 12460 9045706 70.00

SEQ ID NO 12413 8853232 72.73 SEQ ID NO 12461 9045811 70.00

SEQ ID NO 12414 8894228 84.62 SEQ ID NO 12462 9045910 75.00

SEQ ID NO 12415 8905583 91.67 SEQ ID NO 12463 9047478 70.00

SEQ ID NO 12416 8905610 92.86 SEQ ID NO 12464 9047688 84.62

SEQ ID NO 12417 8907714 93.33 SEQ ID NO 12465 9048250 85.71

SEQ ID NO 12418 8907886 93.33 SEQ ID NO 12466 9048316 100.00

SEQ ID NO 12419 8908230 87.50 SEQ ID NO 12467 9048354 100.00

SEQ ID NO 12420 8908267 90.00 SEQ ID NO 12468 9048555 85.71

SEQ ID NO 12421 8908771 100.00 SEQ ID NO 12469 9049356 70.00

SEQ ID NO 12422 8928087 80.00 SEQ ID NO 12470 9049734 100.00 SEQ ID NO 12471 9049777 100.00 SEQ ID NO 12519 9086952 100.00

SEQ ID NO 12472 9049948 100.00 SEQ ID NO 12520 9087010 100.00

SEQ ID NO 12473 9050076 100.00 SEQ ID NO 12521 9087649 83.33

SEQ ID NO 12474 9050111 100.00 SEQ ID NO 12522 9089449 100.00

SEQ ID NO 12475 9050267 75.00 SEQ ID NO 12523 9090212 80.00

SEQ ID NO 12476 9050639 85.71 SEQ ID NO 12524 9090279 80.00

SEQ ID NO 12477 9050837 78.57 SEQ ID NO 12525 9090340 72.73

SEQ ID NO 12478 9051130 83.33 SEQ ID NO 12526 9090602 75.00

SEQ ID NO 12479 9051770 100.00 SEQ ID NO 12527 9091170 84.62

SEQ ID NO 12480 9052144 85.71 SEQ ID NO 12528 9091589 88.89

SEQ ID NO 12481 9052176 85.71 SEQ ID NO 12529 9091789 76.92

SEQ ID NO 12482 9052244 88.89 SEQ ID NO 12530 9091971 90.91

SEQ ID NO 12483 9052286 87.50 SEQ ID NO 12531 9092194 100.00

SEQ ID NO 12484 9052506 100.00 SEQ ID NO 12532 9092776 100.00

SEQ ID NO 12485 9054771 100.00 SEQ ID NO 12533 9093615 75.00

SEQ ID NO 12486 9054805 100.00 SEQ ID NO 12534 9093631 80.00

SEQ ID NO 12487 9054821 100.00 SEQ ID NO 12535 9094370 86.67

SEQ ID NO 12488 9054829 100.00 SEQ ID NO 12536 9094958 92.86

SEQ ID NO 12489 9058270 75.00 SEQ ID NO 12537 9095841 86.67

SEQ ID NO 12490 9059417 100.00 SEQ ID NO 12538 9095899 93.33

SEQ ID NO 12491 9059470 90.91 SEQ ID NO 12539 9096985 86.67

SEQ ID NO 12492 9059485 88.89 SEQ ID NO 12540 9097066 86.67

SEQ ID NO 12493 9059572 100.00 SEQ ID NO 12541 9097661 86.67

SEQ ID NO 12494 9059578 83.33 SEQ ID NO 12542 9098139 76.92

SEQ ID NO 12495 9059682 85.71 SEQ ID NO 12543 9098455 86.67

SEQ ID NO 12496 9059864 100.00 SEQ ID NO 12544 9099615 90.00

SEQ ID NO 12497 9059957 75.00 SEQ ID NO 12545 9099865 88.89

SEQ ID NO 12498 9061332 86.67 SEQ ID NO 12546 9100567 80.00

SEQ ID NO 12499 9065181 100.00 SEQ ID NO 12547 9100757 86.67

SEQ ID NO 12500 9079055 83.33 SEQ ID NO 12548 9102435 75.00

SEQ ID NO 12501 9079104 76.92 SEQ ID NO 12549 9103334 93.33

SEQ ID NO 12502 9080095 100.00 SEQ ID NO 12550 9103735 75.00

SEQ ID NO 12503 9082100 86.67 SEQ ID NO 12551 9103740 75.00

SEQ ID NO 12504 9083087 93.33 SEQ ID NO 12552 9103799 75.00

SEQ ID NO 12505 9084395 100.00 SEQ ID NO 12553 9103843 83.33

SEQ ID NO 12506 9084841 75.00 SEQ ID NO 12554 9103855 75.00

SEQ ID NO 12507 9084953 100.00 SEQ ID NO 12555 9104819 75.00

SEQ ID NO 12508 9085662 75.00 SEQ ID NO 12556 9105872 86.67

SEQ ID NO 12509 9085802 100.00 SEQ ID NO 12557 9106481 93.33

SEQ ID NO 12510 9085886 92.31 SEQ ID NO 12558 9110089 93.33

SEQ ID NO 12511 9085898 92.31 SEQ ID NO 12559 9110519 93.33

SEQ ID NO 12512 9085941 83.33 SEQ ID NO 12560 9112827 83.33

SEQ ID NO 12513 9085947 90.00 SEQ ID NO 12561 9112853 84.62

SEQ ID NO 12514 9085963 87.50 SEQ ID NO 12562 9115136 86.67

SEQ ID NO 12515 9086008 80.00 SEQ ID NO 12563 9116420 86.67

SEQ ID NO 12516 9086051 92.86 SEQ ID NO 12564 9118471 100.00

SEQ ID NO 12517 9086170 100.00 SEQ ID NO 12565 9120602 75.00

SEQ ID NO 12518 9086237 80.00 SEQ ID NO 12566 9127341 100.00 SEQ ID NO 12567 9129766 85.71 SEQ ID NO 12615 9196669 93.33

SEQ ID NO 12568 9129873 86.67 SEQ ID NO 12616 9202812 75.00

SEQ ID NO 12569 9130635 86.67 SEQ ID NO 12617 9209801 93.33

SEQ ID NO 12570 9130655 85.71 SEQ ID NO 12618 9219622 83.33

SEQ ID NO 12571 9130759 86.67 SEQ ID NO 12619 9224162 93.33

SEQ ID NO 12572 9130792 86.67 SEQ ID NO 12620 9224464 93.33

SEQ ID NO 12573 9130801 86.67 SEQ ID NO 12621 9229709 93.33

SEQ ID NO 12574 9131062 86.67 SEQ ID NO 12622 9232640 92.86

SEQ ID NO 12575 9131089 80.00 SEQ ID NO 12623 9232654 92.31

SEQ ID NO 12576 9132595 100.00 SEQ ID NO 12624 9259305 92.86

SEQ ID NO 12577 9132623 100.00 SEQ ID NO 12625 9263429 91.67

SEQ ID NO 12578 9135006 78.57 SEQ ID NO 12626 9269099 88.89

SEQ ID NO 12579 9136214 87.50 SEQ ID NO 12627 9269211 75.00

SEQ ID NO 12580 9136608 83.33 SEQ ID NO 12628 9272561 93.33

SEQ ID NO 12581 9137394 80.00 SEQ ID NO 12629 9277337 80.00

SEQ ID NO 12582 9138023 75.00 SEQ ID NO 12630 9282904 100.00

SEQ ID NO 12583 9139365 83.33 SEQ ID NO 12631 9282958 80.00

SEQ ID NO 12584 9140553 80.00 SEQ ID NO 12632 9282987 93.33

SEQ ID NO 12585 9140953 86.67 SEQ ID NO 12633 9283305 93.33

SEQ ID NO 12586 9141422 86.67 SEQ ID NO 12634 9284246 91.67

SEQ ID NO 12587 9141554 75.00 SEQ ID NO 12635 9284419 100.00

SEQ ID NO 12588 9141716 78.57 SEQ ID NO 12636 9284481 93.33

SEQ ID NO 12589 9143085 86.67 SEQ ID NO 12637 9284687 93.33

SEQ ID NO 12590 9144983 80.00 SEQ ID NO 12638 9285055 100.00

SEQ ID NO 12591 9149760 86.67 SEQ ID NO 12639 9285662 85.71

SEQ ID NO 12592 9156499 100.00 SEQ ID NO 12640 9297634 93.33

SEQ ID NO 12593 9157597 85.71 SEQ ID NO 12641 9297686 93.33

SEQ ID NO 12594 9160536 85.71 SEQ ID NO 12642 9302721 93.33

SEQ ID NO 12595 9161702 72.73 SEQ ID NO 12643 9303797 93.33

SEQ ID NO 12596 9162301 80.00 SEQ ID NO 12644 9304280 84.62

SEQ ID NO 12597 9164166 80.00 SEQ ID NO 12645 9306482 93.33

SEQ ID NO 12598 9164249 85.71 SEQ ID NO 12646 9307284 83.33

SEQ ID NO 12599 9178084 90.91 SEQ ID NO 12647 9307308 83.33

SEQ ID NO 12600 9178618 93.33 SEQ ID NO 12648 9307391 75.00

SEQ ID NO 12601 9181976 92.86 SEQ ID NO 12649 9315451 72.73

SEQ ID NO 12602 9182299 100.00 SEQ ID NO 12650 9315894 80.00

SEQ ID NO 12603 9184760 75.00 SEQ ID NO 12651 9320002 87.50

SEQ ID NO 12604 9185151 87.50 SEQ ID NO 12652 9321227 75.00

SEQ ID NO 12605 9186144 100.00 SEQ ID NO 12653 9321278 100.00

SEQ ID NO 12606 9186737 75.00 SEQ ID NO 12654 9321821 75.00

SEQ ID NO 12607 9187868 100.00 SEQ ID NO 12655 9321865 100.00

SEQ ID NO 12608 9188349 80.00 SEQ ID NO 12656 9321867 100.00

SEQ ID NO 12609 9189197 83.33 SEQ ID NO 12657 9321871 100.00

SEQ ID NO 12610 9189400 80.00 SEQ ID NO 12658 9321939 75.00

SEQ ID NO 12611 9193846 91.67 SEQ ID NO 12659 9333126 100.00

SEQ ID NO 12612 9195812 87.50 SEQ ID NO 12660 9333134 100.00

SEQ ID NO 12613 9195968 93.33 SEQ ID NO 12661 9333395 75.00

SEQ ID NO 12614 9196351 86.67 SEQ ID NO 12662 9333549 100.00 SEQ ID NO 12663 9333599 80.00 SEQ ID NO 12711 9453969 76.92

SEQ ID NO 12664 9333916 100.00 SEQ ID NO 12712 9476760 76.92

SEQ ID NO 12665 9334479 75.00 SEQ ID NO 12713 9479986 83.33

SEQ ID NO 12666 9335750 100.00 SEQ ID NO 12714 9479988 75.00

SEQ ID NO 12667 9336348 100.00 SEQ ID NO 12715 9485172 100.00

SEQ ID NO 12668 9336362 100.00 SEQ ID NO 12716 9485376 100.00

SEQ ID NO 12669 9336640 100.00 SEQ ID NO 12717 9485863 100.00

SEQ ID NO 12670 9336695 100.00 SEQ ID NO 12718 9486131 87.50

SEQ ID NO 12671 9336904 100.00 SEQ ID NO 12719 9486307 100.00

SEQ ID NO 12672 9337741 100.00 SEQ ID NO 12720 9486679 80.00

SEQ ID NO 12673 9337754 100.00 SEQ ID NO 12721 9486868 80.00

SEQ ID NO 12674 9337757 100.00 SEQ ID NO 12722 9490711 80.00

SEQ ID NO 12675 9337765 80.00 SEQ ID NO 12723 9490746 75.00

SEQ ID NO 12676 9337769 80.00 SEQ ID NO 12724 9496652 93.33

SEQ ID NO 12677 9337948 80.00 SEQ ID NO 12725 9500046 93.33

SEQ ID NO 12678 9338023 100.00 SEQ ID NO 12726 9501820 100.00

SEQ ID NO 12679 9338415 100.00 SEQ ID NO 12727 9502432 75.00

SEQ ID NO 12680 9338461 75.00 SEQ ID NO 12728 9504402 100.00

SEQ ID NO 12681 9338686 75.00 SEQ ID NO 12729 9504453 100.00

SEQ ID NO 12682 9338818 100.00 SEQ ID NO 12730 9504503 80.00

SEQ ID NO 12683 9338989 100.00 SEQ ID NO 12731 9507369 93.33

SEQ ID NO 12684 9339661 80.00 SEQ ID NO 12732 9508556 75.00

SEQ ID NO 12685 9339961 85.71 SEQ ID NO 12733 9509565 93.33

SEQ ID NO 12686 9340029 85.71 SEQ ID NO 12734 9518054 70.00

SEQ ID NO 12687 9342021 93.33 SEQ ID NO 12735 9526344 75.00

SEQ ID NO 12688 9342889 80.00 SEQ ID NO 12736 9529768 93.33

SEQ ID NO 12689 9350507 100.00 SEQ ID NO 12737 9535100 75.00

SEQ ID NO 12690 9365366 83.33 SEQ ID NO 12738 9535102 80.00

SEQ ID NO 12691 9365377 93.33 SEQ ID NO 12739 9535143 80.00

SEQ ID NO 12692 9368837 72.73 SEQ ID NO 12740 9546384 100.00

SEQ ID NO 12693 9370125 100.00 SEQ ID NO 12741 9562622 100.00

SEQ ID NO 12694 9370319 80.00 SEQ ID NO 12742 9563173 75.00

SEQ ID NO 12695 9371828 80.00 SEQ ID NO 12743 9564214 93.33

SEQ ID NO 12696 9377460 75.00 SEQ ID NO 12744 9575687 80.00

SEQ ID NO 12697 9401546 90.91 SEQ ID NO 12745 9576060 83.33

SEQ ID NO 12698 9405932 80.00 SEQ ID NO 12746 9580639 93.33

SEQ ID NO 12699 9408119 100.00 SEQ ID NO 12747 9580740 92.86

SEQ ID NO 12700 9409427 100.00 SEQ ID NO 12748 9581028 90.00

SEQ ID NO 12701 9410564 80.00 SEQ ID NO 12749 9581137 83.33

SEQ ID NO 12702 9410638 70.00 SEQ ID NO 12750 9584392 70.00

SEQ ID NO 12703 9411544 100.00 SEQ ID NO 12751 9599157 83.33

SEQ ID NO 12704 9434878 85.71 SEQ ID NO 12752 9629075 100.00

SEQ ID NO 12705 9434913 90.00 SEQ ID NO 12753 9629128 100.00

SEQ ID NO 12706 9434998 88.89 SEQ ID NO 12754 9637376 70.00

SEQ ID NO 12707 9447220 100.00 SEQ ID NO 12755 9642556 93.33

SEQ ID NO 12708 9451762 100.00 SEQ ID NO 12756 9643536 93.33

SEQ ID NO 12709 9452002 100.00 SEQ ID NO 12757 9643540 93.33

SEQ ID NO 12710 9453931 80.00 SEQ ID NO 12758 9643547 93.33 SEQ ID NO 12759 9645281 93.33

SEQ ID NO 12760 9645972 83.33

SEQ ID NO 12761 9654493 75.00

SEQ ID NO 12762 9658114 88.89

SEQ ID NO 12763 9662770 75.00

SEQ ID NO 12764 9664759 80.00

SEQ ID NO 12765 9669456 84.62

SEQ ID NO 12766 9673199 75.00

SEQ ID NO 12767 9678264 93.33

EXAMPLE 6: METHOD OF PREDICTING AND DETERMINING FRUIT EXOCARP COLOUR OF AN OIL PALM FRUIT

A sample of an oil palm plant to be analysed is obtained. DNA is extracted from the sample consisting of leaves, spear leaves, stem, saplings, roots, seed, fruit, and parts thereof using the conventional phenol-chloroform method or any commercial DNA extraction kits or crude DNA extraction methods as known in the art.

The DNA is then genotyped using PCR based methods together with allele specific oligonucleotides (ASO) designed to amplify the markers from Tables 3 to 10. It should be noted that other methods of genotyping such as sequencing, microarray and the like are known in the art and may also be used to determine the genotype of the particular loci in the oil palm plant. The resulting sequence for this sample may then be compared with the list of known markers in Tables 3 to 10, so as to determine if the plant from which the sample was obtained from has the nigrescens or the virescens trait. For example, with reference to Table 3, if the sequence from the plant sample comprises a sequence amplified by SEQ ID NO: 12853 (forward primer) and SEQ ID NO: 12982 (reverse primer), exhibiting an insertion of nucleotide "A" at a position that corresponds to position 3252004 of SEQ ID NO: 13295 , then it may be inferred that the plant will display the virescens trait.

Similarly, with reference to Table 4, if the sequence from the plant sample comprises a sequence amplified by SEQ ID NO: 12785 (forward primer) and SEQ ID NO: 12914 (reverse primer), exhibiting a (TG)₁₇ SSR at positions that correspond to positions 3208714 to 3208747 of SEQ ID NO: 13295, then it may be inferred that the plant will display the virescens trait.

Alternatively, with reference to Table 7, if the sequence from the plant sample comprises the alleles "TT" in SEQ ID NO: 4901 at a position that correspond to position 4759393 of SEQ ID NO: 13295, then it may be inferred that the plant will display the nirescens trait. If the sequence from the plant sample comprises the alleles "CC" or "CT" in SEQ ID NO: 4901 at that position, then it may be inferred that the plant will display the virescens trait. It is envisaged that the fruit exocarp trait of any oil palm plant sample can be predicted and determined using the information from Tables 3 to 10 in a similar manner as described in this Example 6.

All documents cited in this text ("herein cited documents") and all documents cited or referenced in herein cited documents and sequences from GenBank and other data bases referred to herein are incorporated by reference in their entirety for all purposes. There is no admission that any of the various documents etc. cited in this text are prior art as to the present invention.

Claims

1. A method of predicting or determining fruit exocarp trait of an oil palm fruit, the method comprising detecting the presence or absence of one or more genetic markers located in Haplotype Block A, wherein Haplotype Block A comprises or consists of SEQ ID NO: SEQ ID NO: 13295 or SEQ ID NOs: 13020 to 13294.

2. The method of claim 1, wherein the Haplotype Block A is associated with a genetic region of the oil palm genome that regulates fruit exocarp colour in oil palm.

3. The method of claim 1 or 2, wherein the genetic marker located in the Haplotype Block A is selected from a group consisting of SEQ ID NOs: 1 to 12767, the markers listed in Table 3 and the markers listed in Table 4

4. The method of any one of the preceding claims, wherein the Haplotype Block A comprises Haplotype Block B, comprising of base pair 18836 of SEQ ID NO: 13029 to base pair 158067 of SEQ ID NO: 13256, or SEQ ID NO: 13296.

5. The method of claim 4, wherein the Haplotype Block B comprises a genetic marker selected from a group consisting of SEQ ID NOs: 11 to 9172, the markers listed in Table 4, and the markers listed in Table 3 .

6. The method of claim 4, wherein the Haplotype Block B comprises a genetic marker selected from a group consisting of SEQ ID NO: 11, SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID

NO: 4903, SEQ ID NO: 4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, SEQ ID NO: 4909, SEQ ID NO: 4910, SEQ ID NO: 4911, SEQ ID NO: 4912, SEQ ID NO: 4913, SEQ ID NO: 4914, SEQ ID NO: 9168, SEQ ID NO: 9169, SEQ ID NO: 9170, SEQ ID NO: 9171, SEQ ID NO: 9173, SEQ ID NO: 9174, SEQ ID NO: 9175, SEQ ID NO: 9176, SEQ ID NO: 9177, SEQ ID NO:

9178, SEQ ID NO: 9179, SEQ ID NO: 9180, SEQ ID NO: 9181, SEQ ID NO: 9182, SEQ ID NO: 9183, and SEQ ID NO: 9184.

7. The method of claim 4, wherein the Haplotype Block B comprises a gene selected from a group consisting of MYB001 (SEQ ID NO: 12891), MYB002 (SEQ ID NO: 12892) and MYB003 (SEQ ID NO: 12893), or a variant thereof having more than 70%, 80%, 90%, 95%, 98% or 99% sequence identity to one of SEQ ID NOs: 12891 to 12893.

8. The method of claim 4, wherein the Haplotype Block B comprises Haplotype Block C, comprising of base pair 39774 of SEQ ID NO: 13123 to base pair 21091 of SEQ ID NO: 13215, or SEQ ID NO: 13297.

9. The method of claim 8, wherein the Haplotype Block C comprises a genetic marker selected from a group consisting of SEQ ID NOs: 2860 to 6898, the markers listed in Table 4, and the markers listed in Table 3.

10. The method of claim 8, wherein the Haplotype Block C comprises a genetic marker selected from a group consisting of SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID NO: 4903, SEQ ID NO: 4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, SEQ ID NO: 4909, SEQ ID NO: 4910, SEQ ID NO: 4911, SEQ ID NO: 4912, SEQ ID NO: 4913, and SEQ ID NO: 4914.

11. The method of claim 8, wherein the Haplotype Block C comprises the gene MYB002 (SEQ ID NO: 12892), or a variant thereof having more than 70%, 80%, 90%, 95%, 96%, 97%, 98% or 99% sequence identity to SEQ ID NO: 12892.

12. The method of claim 7 or 11 wherein the gene MYB002 (SEQ ID NO: 12892) comprises a genetic marker selected from a group consisting of SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID NO: 4903, SEQ ID NO: 4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, and SEQ ID NO: 4909.

13. The method of any one of the preceding claims, wherein the genetic marker is SEQ ID NO: 4901.

14. The method of claim 7, wherein the genes MYB001 (SEQ ID NO: 12891),

MYB002 (SEQ ID NO: 12892) and MYB003 (SEQ ID NO: 12893) each encodes a transcription factor.

15. The method of claim 14, wherein the transcription factor comprises SEQ ID NO: 12894, SEQ ID NO: 12895 and SEQ ID NO: 12896, or a variant thereof having more than 70%, 80%, 90%, 95%, 96%, 97%, 98% or 99% sequence identity to one of SEQ ID NOs: 12894 to 12896.

16. The method of claim 14 or 15, wherein the transcription factor comprises a MYB DNA binding domain.

17. The method of any one of the preceding claims, wherein the detecting of the presence or absence of one or more genetic marker is conducted on a plant or a plant sample containing genetic material and/or proteinaceous material.

18. The method of claim 17, wherein the plant sample is selected from a group consisting of leaves, spear leaves, stem, saplings, roots, buds, flowers, seed, fruit, and parts thereof.

19. The method of any one of the preceding claims, wherein the genetic marker is selected from a group consisting of single nucleotide polymorphism (SNP), simple sequence repeats (SSRs), insertion or the deletion of bases (INDel), unique-event polymorphism (UEP) and short tandem repeat (STR).

20. The method of claim 19, wherein the genetic marker is a single nucleotide polymorphism (SNP) or simple sequence repeats (SSRs).

21. The method of any one of the preceding claims, wherein a plurality of the genetic markers is inherited as a haplotype.

22. The method of any one of the preceding claims, wherein the fruit exocarp colour is a trait selected from the group consisting of Nigrescens and Virescens.

23. The method of any one of the preceding claims, comprising the step of determining that at least one, or all genetic markers, selected from a group consisting of SEQ ID NOs: 1 to 12767 are indicative of the fruit exocarp colour trait of Nigrescens.

24. The method of any one of the preceding claims, comprising the step of determining that at least one, or all genetic markers, selected from a group consisting of SEQ ID NO: 11, SEQ ID NO: 4898, SEQ ID NO: 4899, SEQ ID NO: 4900, SEQ ID NO: 4901, SEQ ID NO: 4902, SEQ ID NO: 4903, SEQ ID NO: 4904, SEQ ID NO: 4905, SEQ ID NO: 4906, SEQ ID NO: 4907, SEQ ID NO: 4908, SEQ ID NO: 4909, SEQ ID NO: 4910, SEQ ID NO: 4911, SEQ ID NO: 4912, SEQ ID NO: 4913,

SEQ ID NO: 4914, SEQ ID NO: 9168, SEQ ID NO: 9169, SEQ ID NO: 9170, SEQ ID NO: 9171, SEQ ID NO: 9173, SEQ ID NO: 9174, SEQ ID NO: 9175, SEQ ID NO: 9176, SEQ ID NO: 9177, SEQ ID NO: 9178, SEQ ID NO: 9179, SEQ ID NO: 9180, SEQ ID NO: 9181, SEQ ID NO: 9182, SEQ ID NO: 9183, and SEQ ID NO: 9184 are indicative of the fruit exocarp colour trait of Virescens.

25. The method of any one of the preceding claims, comprising the step of determining that at least one, or all genetic markers, selected from a group consisting of the markers listed in Table 4 are indicative of the fruit exocarp colour trait of Virescens.

26. The method of any one of the preceding claims, comprising the step of determining that at least one, or all genetic markers, selected from a group consisting of the markers listed in Table 3 are indicative of the fruit exocarp colour trait of Virescens.

27. The method of any one of claims 23 to 26, wherein the fruit exocarp colour traits of Nigrescens and Virescens are mutually exclusive.

28. A method for selecting an oil palm plant for breeding, comprising using one or more genetic marker as defined in any one of the preceding claims, wherein the selection is based on the presence or absence of the genetic marker within a Haplotype Block as defined in any one of the preceding claims.