WO2016004255A3 - Holey capsid platform - Google Patents
Holey capsid platform Download PDFInfo
- Publication number
- WO2016004255A3 WO2016004255A3 PCT/US2015/038907 US2015038907W WO2016004255A3 WO 2016004255 A3 WO2016004255 A3 WO 2016004255A3 US 2015038907 W US2015038907 W US 2015038907W WO 2016004255 A3 WO2016004255 A3 WO 2016004255A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- capsid
- holey
- platform
- modifying
- create
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10123—Virus like particles [VLP]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
A self-assembling protein capsid including removable sub-units is disclosed along with a method for modifying a capsid to create a holey capsid.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462019719P | 2014-07-01 | 2014-07-01 | |
US62/019,719 | 2014-07-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2016004255A2 WO2016004255A2 (en) | 2016-01-07 |
WO2016004255A3 true WO2016004255A3 (en) | 2016-02-25 |
Family
ID=55020099
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2015/038907 WO2016004255A2 (en) | 2014-07-01 | 2015-07-01 | Holey capsid platform |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2016004255A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021163538A1 (en) * | 2020-02-13 | 2021-08-19 | The Trustees Of Indiana University | Hepadnavirus capsid protein heterodimers and virus-like particles |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120121713A1 (en) * | 2009-04-14 | 2012-05-17 | De Los Rios Miguel | Chimeric therapeutics, compositions, and methods for using same |
-
2015
- 2015-07-01 WO PCT/US2015/038907 patent/WO2016004255A2/en active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120121713A1 (en) * | 2009-04-14 | 2012-05-17 | De Los Rios Miguel | Chimeric therapeutics, compositions, and methods for using same |
Non-Patent Citations (2)
Title |
---|
NEWCOMB ET AL.: "Cell -free assembly of the herpes simplex virus capsid.", J VIROL, vol. 68, no. 9, September 1994 (1994-09-01), pages 6059 - 6063, XP002923911 * |
SZCZEPANIAK ET AL.: "Disulfide bond formation contributes to herpes simplex virus capsid stability and retention of pentons.", J VIROL, vol. 85, no. 17, September 2011 (2011-09-01), pages 8625 - 8634 * |
Also Published As
Publication number | Publication date |
---|---|
WO2016004255A2 (en) | 2016-01-07 |
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