WO2015191636A3 - Xanthine oxidase inhibitors and methods of use - Google Patents
Xanthine oxidase inhibitors and methods of use Download PDFInfo
- Publication number
- WO2015191636A3 WO2015191636A3 PCT/US2015/034971 US2015034971W WO2015191636A3 WO 2015191636 A3 WO2015191636 A3 WO 2015191636A3 US 2015034971 W US2015034971 W US 2015034971W WO 2015191636 A3 WO2015191636 A3 WO 2015191636A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- xanthine oxidase
- oxidase inhibitors
- inhibitors
- xanthine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Xanthine oxidase inhibitors are provided, as well as compositions, methods for their use for treating disorders, mediated at least in part, by xanthine oxidase.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462009810P | 2014-06-09 | 2014-06-09 | |
US62/009,810 | 2014-06-09 | ||
US201462060515P | 2014-10-06 | 2014-10-06 | |
US62/060,515 | 2014-10-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2015191636A2 WO2015191636A2 (en) | 2015-12-17 |
WO2015191636A3 true WO2015191636A3 (en) | 2016-03-10 |
Family
ID=54834545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2015/034971 WO2015191636A2 (en) | 2014-06-09 | 2015-06-09 | Xanthine oxidase inhibitors and methods of use |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2015191636A2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105753774A (en) * | 2016-03-31 | 2016-07-13 | 常州大学 | Synthesis method for 2-hydroxyl-3-nitro-4-formylpyridine |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4803225A (en) * | 1983-12-06 | 1989-02-07 | Fisons, Plc | Dihydroxy-phenethylamino compounds useful as pharmaceuticals |
US5399577A (en) * | 1991-05-01 | 1995-03-21 | Taiho Pharmaceutical Co., Ltd. | Isoxazole derivatives and salts thereof |
US6121303A (en) * | 1992-10-23 | 2000-09-19 | Orion-Yhtyma Oy | Pharmacologically active catechol derivatives |
US6169092B1 (en) * | 1996-07-12 | 2001-01-02 | Bayer Aktiengesellschaft | 3-Ureido-pyridofurans and -pyridothiophenes for the treatment of inflammatory processes |
-
2015
- 2015-06-09 WO PCT/US2015/034971 patent/WO2015191636A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4803225A (en) * | 1983-12-06 | 1989-02-07 | Fisons, Plc | Dihydroxy-phenethylamino compounds useful as pharmaceuticals |
US5399577A (en) * | 1991-05-01 | 1995-03-21 | Taiho Pharmaceutical Co., Ltd. | Isoxazole derivatives and salts thereof |
US6121303A (en) * | 1992-10-23 | 2000-09-19 | Orion-Yhtyma Oy | Pharmacologically active catechol derivatives |
US6169092B1 (en) * | 1996-07-12 | 2001-01-02 | Bayer Aktiengesellschaft | 3-Ureido-pyridofurans and -pyridothiophenes for the treatment of inflammatory processes |
Non-Patent Citations (2)
Title |
---|
DATABASE PubChem 5 December 2007 (2007-12-05), Database accession no. 22112903 * |
LU ET AL.: "3,4-Dihydroxy-5-nitrobenzaldehyde (DHNB) is a Potent Inhibitor of Xanthine Oxidase: a potential therapeutic agent for treatment of hyperuricemia and gout", BIOCHEM PHARMACOL., vol. 86, no. 9, 2013, pages 22 * |
Also Published As
Publication number | Publication date |
---|---|
WO2015191636A2 (en) | 2015-12-17 |
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