WO2015184249A3 - Sle and sle-related disease-associated risk markers and uses thereof - Google Patents
Sle and sle-related disease-associated risk markers and uses thereof Download PDFInfo
- Publication number
- WO2015184249A3 WO2015184249A3 PCT/US2015/033161 US2015033161W WO2015184249A3 WO 2015184249 A3 WO2015184249 A3 WO 2015184249A3 US 2015033161 W US2015033161 W US 2015033161W WO 2015184249 A3 WO2015184249 A3 WO 2015184249A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sle
- related disease
- risk markers
- subjects
- associated risk
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
Provided herein are methods and compositions for identifying subjects, including canine subjects, as having an elevated risk of developing systemic lupus erythematosus (SLE) or an SLE-related immune-mediated rheumatic disorder, such as IMRD or SRMA, or having undiagnosed SLE or an SLE-related immune-mediated rheumatic disorder, such as IMRD or SRMA. These subjects are identified based on the presence of germ-line risk markers.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462005828P | 2014-05-30 | 2014-05-30 | |
US62/005,828 | 2014-05-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2015184249A2 WO2015184249A2 (en) | 2015-12-03 |
WO2015184249A3 true WO2015184249A3 (en) | 2016-01-28 |
Family
ID=54700068
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2015/033161 WO2015184249A2 (en) | 2014-05-30 | 2015-05-29 | Sle and sle-related disease-associated risk markers and uses thereof |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2015184249A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111518885A (en) * | 2020-04-22 | 2020-08-11 | 深圳市福田区风湿病专科医院 | Method for detecting mutation sites of systemic lupus erythematosus genes |
US11574738B2 (en) | 2020-04-30 | 2023-02-07 | Optum Services (Ireland) Limited | Cross-variant polygenic predictive data analysis |
US11610645B2 (en) | 2020-04-30 | 2023-03-21 | Optum Services (Ireland) Limited | Cross-variant polygenic predictive data analysis |
US11978532B2 (en) | 2020-04-30 | 2024-05-07 | Optum Services (Ireland) Limited | Cross-variant polygenic predictive data analysis |
US11967430B2 (en) | 2020-04-30 | 2024-04-23 | Optum Services (Ireland) Limited | Cross-variant polygenic predictive data analysis |
US11482302B2 (en) | 2020-04-30 | 2022-10-25 | Optum Services (Ireland) Limited | Cross-variant polygenic predictive data analysis |
-
2015
- 2015-05-29 WO PCT/US2015/033161 patent/WO2015184249A2/en active Application Filing
Non-Patent Citations (4)
Title |
---|
JOKINEN, P.: "Identifying Genetic Risk Factors In Canine Autoimmune Disorders.", ACADEMIC DISSERTATION., 28 January 2011 (2011-01-28), Retrieved from the Internet <URL:https://helda.helsinki.fi/bitstream/handle/10138/24488/identify.pdf> [retrieved on 20151008] * |
TRUVE, K.: "Bioinformatics Mining For Disease Causing Mutations: Using The Dog Genome As A Model For Human Disease.", DOCTORAL THESIS., 2012, Retrieved from the Internet <URL:http://hunddna.slu.selartikelserie/truve_k_120920.pdf> [retrieved on 20151008] * |
WILBE, M ET AL.: "Genome-Wide Association Mapping Identifies Multiple Loci For A Canine SLE-Related Disease Complex.", NAT GENET., vol. 42, no. 3, March 2010 (2010-03-01), pages 250 - 254 * |
WILBE, M.: "Discovery Of A Novel Pathway For An SLE-Related Disease Complex In The Canine Breed Nova Scotia Duck Tolling Retriever.", SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES UPPSALA. DOCTORAL THESIS., 2013, Retrieved from the Internet <URL:http://pub.epsilon.siu.se/10229/1/wilbe_m_130415.pdf> [retrieved on 20151008] * |
Also Published As
Publication number | Publication date |
---|---|
WO2015184249A2 (en) | 2015-12-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2015184249A3 (en) | Sle and sle-related disease-associated risk markers and uses thereof | |
CY1120988T1 (en) | MOVEMENT DIAHREL INHIBITORS | |
CL2017001408A1 (en) | Anti-cd79b antibodies and methods of use | |
MX2017003478A (en) | Anti-fgfr2/3 antibodies and methods using same. | |
BR112017013448A2 (en) | liquid sulfonylurea-containing herbicide compositions | |
WO2014152355A3 (en) | Osteosarcoma-associated risk markers and uses thereof | |
FR3041511B1 (en) | DEVICE FOR CONDITIONING AN EMULSION | |
WO2018071796A3 (en) | Compositions and methods for identifying functional anti-tumor t cell responses | |
FR3037569B1 (en) | AXIAL MAGNETIC ATTRACTION DEVICE. | |
DK3214927T3 (en) | LIQUID COLLECTION SYSTEM FOR FLOWS ON THE FLOOR OF AN ANIMAL BREEDING INCLUSION | |
ZA201902996B (en) | Stable solid composition based on an aromatic compound and uses thereof | |
BR112017028470A2 (en) | 6.6 high module nylon cables | |
EP3492541A4 (en) | Compositions based on emulsions of wax and particulate inorganic compounds for improved water-repellency, and the use thereof | |
FR3018672B1 (en) | DEVICE FOR CONDITIONING AND APPLICATION. | |
BR112019006636A2 (en) | low emission pre-vulcanization inhibitor for polyurethane foam | |
WO2014169204A3 (en) | Sle and sle-related disease-associated risk markers and uses thereof | |
FR3047109B1 (en) | COOLING ASSEMBLY OF AN INDUCTANCE DEVICE | |
EP3519571A4 (en) | Compositions, methods and systems for identifying candidate nucleic acid agent | |
BR112018013888A2 (en) | diurnosid and / or cestrumosid animal feed additive | |
Thammishetty | Educational Evaluation | |
Karaküçük | Effects of accountants’ demographic characteristics on ethical behaviors | |
FR3016892B1 (en) | DEVICE FOR PREHEATING AN ANODE ASSEMBLY. | |
WO2014160359A8 (en) | Mast cell cancer-associated germ-line risk markers and uses thereof | |
Dixon | Field Journal of JR Dixon (JRD Specimens 30722-30957) | |
Dixon | Field Journal of JR Dixon (JRD Specimens 30622-30721) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 15799423 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 15799423 Country of ref document: EP Kind code of ref document: A2 |