WO2015132248A3 - Sequamers - a non-natural type of peptide libraries randomly constrained by their primary sequences - Google Patents

Sequamers - a non-natural type of peptide libraries randomly constrained by their primary sequences Download PDF

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Publication number
WO2015132248A3
WO2015132248A3 PCT/EP2015/054397 EP2015054397W WO2015132248A3 WO 2015132248 A3 WO2015132248 A3 WO 2015132248A3 EP 2015054397 W EP2015054397 W EP 2015054397W WO 2015132248 A3 WO2015132248 A3 WO 2015132248A3
Authority
WO
WIPO (PCT)
Prior art keywords
constrained
peptide libraries
sequamers
primary sequences
natural type
Prior art date
Application number
PCT/EP2015/054397
Other languages
French (fr)
Other versions
WO2015132248A2 (en
Inventor
Martin Zizi
Jurgen FIGYS
Original Assignee
Vrije Universiteit Brussel (Vub)
Belgian Ministry Of Defense
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vrije Universiteit Brussel (Vub), Belgian Ministry Of Defense filed Critical Vrije Universiteit Brussel (Vub)
Publication of WO2015132248A2 publication Critical patent/WO2015132248A2/en
Publication of WO2015132248A3 publication Critical patent/WO2015132248A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Abstract

The present application belongs to the field of functional peptides and more particularly to the field of non-naturally occurring random peptides that are constrained by their primary sequences. The invention discloses molecules of a peptide structure as defined in the claims and methods of using such molecules for therapeutic applications and for diagnostic uses, as well as in other applications such as in the agbio field and in industrial biotechnology. The present invention also provides random peptide libraries of non-naturally occurring peptides.
PCT/EP2015/054397 2014-03-03 2015-03-03 Sequamers - a novel non-natural type of peptide libraries randomly constrained by their primary sequences WO2015132248A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201461947292P 2014-03-03 2014-03-03
US61/947,292 2014-03-03

Publications (2)

Publication Number Publication Date
WO2015132248A2 WO2015132248A2 (en) 2015-09-11
WO2015132248A3 true WO2015132248A3 (en) 2016-01-14

Family

ID=52672246

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2015/054397 WO2015132248A2 (en) 2014-03-03 2015-03-03 Sequamers - a novel non-natural type of peptide libraries randomly constrained by their primary sequences

Country Status (1)

Country Link
WO (1) WO2015132248A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001045746A2 (en) * 1999-12-24 2001-06-28 Genentech, Inc. Methods and compositions for prolonging elimination half-times of bioactive compounds
WO2002076489A1 (en) * 2001-03-09 2002-10-03 Dyax Corp. Serum albumin binding moieties
WO2004065416A2 (en) * 2003-01-16 2004-08-05 Genentech, Inc. Synthetic antibody phage libraries
CA2863126A1 (en) * 2012-01-30 2013-08-08 Katholieke Universiteit Leuven Modified epitopes for boosting cd4+ t-cell responses

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001045746A2 (en) * 1999-12-24 2001-06-28 Genentech, Inc. Methods and compositions for prolonging elimination half-times of bioactive compounds
WO2002076489A1 (en) * 2001-03-09 2002-10-03 Dyax Corp. Serum albumin binding moieties
WO2004065416A2 (en) * 2003-01-16 2004-08-05 Genentech, Inc. Synthetic antibody phage libraries
CA2863126A1 (en) * 2012-01-30 2013-08-08 Katholieke Universiteit Leuven Modified epitopes for boosting cd4+ t-cell responses

Also Published As

Publication number Publication date
WO2015132248A2 (en) 2015-09-11

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