WO2015100180A8 - Compositions and methods for control of industrial scale production of bio-products - Google Patents

Compositions and methods for control of industrial scale production of bio-products Download PDF

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Publication number
WO2015100180A8
WO2015100180A8 PCT/US2014/071691 US2014071691W WO2015100180A8 WO 2015100180 A8 WO2015100180 A8 WO 2015100180A8 US 2014071691 W US2014071691 W US 2014071691W WO 2015100180 A8 WO2015100180 A8 WO 2015100180A8
Authority
WO
WIPO (PCT)
Prior art keywords
control
bio
products
methods
compositions
Prior art date
Application number
PCT/US2014/071691
Other languages
French (fr)
Other versions
WO2015100180A1 (en
Inventor
Lori J. EULER
Dana M.W. POLLAK
Virgil A. RHODIUS
Tina K. Van Dyk
Original Assignee
Danisco Us Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc. filed Critical Danisco Us Inc.
Publication of WO2015100180A1 publication Critical patent/WO2015100180A1/en
Publication of WO2015100180A8 publication Critical patent/WO2015100180A8/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0044—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on other nitrogen compounds as donors (1.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y107/00—Oxidoreductases acting on other nitrogenous compounds as donors (1.7)
    • C12Y107/99—Oxidoreductases acting on other nitrogenous compounds as donors (1.7) with other acceptors (1.7.99)
    • C12Y107/99004—Nitrate reductase (1.7.99.4)

Abstract

The invention provides compositions and methods for microorganisms that have been engineered to produce and/or to improve efficiency of production of bio-products using nitrate-dependent gene expression control constructs to control the expression of heterologously expressed nucleic acids.
PCT/US2014/071691 2013-12-23 2014-12-19 Compositions and methods for control of industrial scale production of bio-products WO2015100180A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361920357P 2013-12-23 2013-12-23
US61/920,357 2013-12-23

Publications (2)

Publication Number Publication Date
WO2015100180A1 WO2015100180A1 (en) 2015-07-02
WO2015100180A8 true WO2015100180A8 (en) 2015-09-17

Family

ID=53479589

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/071691 WO2015100180A1 (en) 2013-12-23 2014-12-19 Compositions and methods for control of industrial scale production of bio-products

Country Status (1)

Country Link
WO (1) WO2015100180A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021505154A (en) 2017-12-07 2021-02-18 ザイマージェン インコーポレイテッド Designed biosynthetic pathway for producing (6E) -8-hydroxygeraniol by fermentation
EP3728212A1 (en) 2017-12-21 2020-10-28 Zymergen Inc. Nepetalactol oxidoreductases, nepetalactol synthases, and microbes capable of producing nepetalactone

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7365185B2 (en) * 2000-07-19 2008-04-29 Monsanto Technology Llc Genomic plant sequences and uses thereof
KR100972843B1 (en) * 2007-03-22 2010-07-28 주식회사 바이오리더스 Novel Constitutive Strong Promoter and Use Thereof

Also Published As

Publication number Publication date
WO2015100180A1 (en) 2015-07-02

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