WO2015076642A1

WO2015076642A1 - Porous body with improved processability, and manufacturing method and processing method therefor

Info

Publication number: WO2015076642A1
Application number: PCT/KR2014/011370
Authority: WO
Inventors: 이명현; 서원선; 공은배; 강종호
Original assignee: 한국세라믹기술원
Priority date: 2013-11-25
Filing date: 2014-11-25
Publication date: 2015-05-28
Also published as: KR20150060089A; KR101569119B1

Abstract

The present invention relates to a porous body with improved processability, and a manufacturing method and a processing method therefor. More specifcially, the present invention provides a method for manufacturing a porous body with improved processability, comprising the steps of: preparing a monomer or prepolymer in solution state, or a resin in melted state; immersing the porous body in the monomer or prepolymer in solution state, or in the resin in melted state so that the resin permeates the pores of the porous body; and curing or coagulating, by photopolymerization, thermal polymerization or cooling, the resin that has permeated the porous body.

Description

Porous body with improved workability, manufacturing method and processing method

The present invention relates to a porous body with improved workability, a method for manufacturing the same, and a processing method, and more particularly, preparing a unit or partial polymer in a solution state or a resin in a molten state; Submerging the porous body in the solution unit or partial polymer or in the molten resin to allow the resin to penetrate the pores of the porous body; And curing or solidifying the resin penetrated into the porous body by photopolymerization, thermal polymerization, or cooling, to provide a method of manufacturing a porous body having improved processability.

Porous body refers to a material comprising a plurality of pores. Porosity in materials may be a cause of fracture defects and therefore must be controlled for minimization, whereas porous bodies that actively use pores are used in many industries. Typical applications include artificial biomaterials, dust filters, catalysts and catalyst carriers, adsorbents, thermal insulation materials, filtration materials, electrode materials, lightweight structural materials, and shock absorbers. The pore size and its distribution in the porous body are the most important factors. If the pore size is determined according to the purpose, the pore size should be uniformly distributed.

In particular, artificial bone substitutes bone tissue in the dental and orthopedic concept as the artificial biological material. In particular, the main bone tissue in the dental concept is the alveolar bone, and the alveolar bone is a general term for the bone tissue surrounding the teeth, and the open pore. Since it is a highly porous structure with a porosity of 30 to 90% as a standard, the strength is weaker than that of other bone tissues, and it is easily absorbed in relation to internal and external stimuli, or is easily lost in parallel with gum disease. Therefore, the tooth is easily shaken or extracted naturally, and once extracted, the tooth cannot be transplanted again, so there is a difficulty in relying on an implant procedure. In recent years, the number of procedures for restoring teeth depending on the implant procedure is increasing rapidly. However, even when an implant procedure is required, the fixture, which is the artificial root portion of the implant, must be firmly fixed in the alveolar bone. It's not easy.

For implantation, alveolar bone must be regenerated. The alveolar bone regeneration method includes autologous bone graft and pulled bone development, but separate surgery is required to collect bone tissue, and the amount that can be collected is limited. , Goal posts, etc. are used.

Particularly, in the case of bone replacement system, specific conditions must be satisfied. Such conditions include absorbency to existing adjacent bone tissue, long-term stability after transplantation, mechanical strength, surface roughness, bone formation, and osteoinduction ability. Even if the bone frame material satisfying the condition is secured, in order to realize the characteristics such as the sponge tissue of the alveolar bone, it must be made of a highly porous material, at this time, there is a problem that processing is not easy. The necessity of processing originates from the fact that each patient differs according to the structure and loss of alveolar bone to which augmentation is applied, defect volume and internal structure of defect.

Specifically, the materials used for the bone aggregates include calcium phosphate-based materials such as apatite (HA), calcium triphosphate (TCP), and biphasic Calcium Phosphate (BCP) mixed with biomaterials, and gypsum-based materials. Each of these may be used alone, or may be used in combination, and it is produced as a bone substitute by applying various manufacturing processes. Here, by controlling the amount of HA and TCP phase, there is an advantage that the biodegradation rate of the porous calcium phosphate ceramics can be controlled, and researches on the composite composed of HA and TCP for improving bone conductivity and controlling biodegradation rate are continuously conducted. .

As the manufacturing method of the framework material, organic combustion method, foaming method, gel casting method, poly sponge method, gel casting method and foaming method are mixed, gel casting method and polymer sponge method are mixed. And the like.

In the restoration and augmentation of the alveolar bone using the bone base material, the granular shape produced is filled or the block shape is trimmed as close as necessary to the required shape by hand using a surgical tool and the granular powder is filled in the unmatched part. By adjusting the bone stay to match the gum structure of the patient as much as possible.

However, in the case of the granular form, even if it is embedded in the gum, there is a problem that the discharge along with the blood of the patient outflow during the procedure, since the shape is not fixed, there is a possibility that deformation occurs even after transplantation. In addition, even in the form of a block-like bone aggregate may not be secured by manual processing.

Recently, the application of the CAD / CAM process is rapidly increasing in the manufacture of dental prostheses such as artificial dental crowns, veneers, onlays, and inlays, and it is attempting to apply the strengths of this process to bone augmentation. . However, the block-type frame member to which the CAD / CAM process is applied is a high porosity open pore structure as described above, there is a problem that the mechanical processing itself is not easy. That is, the bone member has a very weak mechanical strength to break up to an unintended area during mechanical processing, or a very difficult to process into a complicated shape.

The present invention has been made to solve the above-mentioned problems, and an object of the present invention is to enable precise processing of a highly porous framework material having a high porosity.

In addition, another object of the present invention is to enable the bone frame material to be processed to minimize the loss of material.

In addition, the present invention by precisely processing the bone replacement material, it is possible to increase the consistency of the gum structure or defect area of the patient requiring alveolar bone graft, thus the new bone is formed uniformly and stably, the implant of the implant placed in the bone replacement material It is another object to increase the patient's satisfaction by improving the coupling characteristics.

In addition, since the present invention is capable of precise processing of the bone frame material, it is manufactured according to the volume and shape of the required bone replacement portion, there is no need to use another substitute material, and thus the procedure can be made simple and accurate, such as implants in the planned position Another object is to enable accurate placement of prostheses and without the need for granular or other separate structures.

In addition, another object of the present invention is to provide a method that can easily produce a bone frame material in a state capable of processing.

The present invention is to provide a unit or partial polymer, or a resin in the molten state of the solution state to achieve the above object; Submerging the porous body in the solution unit or partial polymer or molten resin to allow the unit or partial polymer or resin to penetrate the pores of the porous body; And polymerizing or curing the unit or partial polymer permeated into the porous body by an initiator, light or heat, or solidifying the melt-penetrated resin by cooling. .

The solution unit or partial polymer is in a solution state at room temperature and is preferably polymerized and cured by an initiator, light or heat.

The resin in which the monomer or partial polymer of the solution state is polymerized is polyethylene (PE), low density polyethylene (LDPE), medium density polyethylene (MDPE), high density polyethylene (HDPE), polypropylene (PP), polystyrene (PS), poly Vinyl chloride (PVC), ABS resin (acrylonitrile-butadiene-styrene resin), acrylonitrile-styrene resin (ASTNWL, S-AN), polymethyl methacrylate (methacrylic resin, PMMA), polyamide (Nylon, PA), polyacetal (POM), polycarbonate (PC), polyethylene terephthalate (PET, PETP), polybutylene terephthalate (PBT, abbreviation PBTP), modified polyphenylene ether, fluoroplastics , Phenolic resin (PE), urea resin (UF), melamine resin (MF), unsaturated polyester resin (UP), epoxy resin (ER), polyurethane (PUR), silicone resin (SI), alkyd resin (ALK) It is preferable to include.

The molten or dissolved resin is preferably solid at room temperature, melted or dissolved by heating or a solvent, and solidified by cooling.

The resin in the molten state may be polyethylene (PE), polyester, polypropylene (PP), polystyrene (PS), polyvinyl chloride (PVC), polymethyl methacrylate (PMMA), polyamide (PA), polycarbonate ( PC) or thermosetting resins including polyethylene terephthalate (PET), polyethylene wax, polypropylenr wax, polyoxyethylen glycol wax, halogenated hydrocarbon wax, Dental waxes including hydrogenated waxes or wax esters; Paraffin wax, Liquid paraffin, Microcrystalline wax, Petrolatum, Barnsdah wax, Ozokerite, Montan wax or three Petroleum waxes including resins; Animal waxes including wool wax, soy wax, lanolin or bees wax; Includes Japan wax, Cocoa butter, Carnauba wax, Crystal palm wax, Candellia wax or Ouricury wax Vegetable waxes; Polyethylene wax, Granule Wax, White wax, Gel wax, Polymer of Phthalic Anhydride and Ethylene Glycol, Fischer-Tropsch Wax Synthetic waxes including Fischer-Tropsch wax or Multi wax; It is preferred to include naturally occurring resins including Sandrac, Rosin or Shellac.

The resin in the molten state is in a molten state at a temperature of 70 ~ 300 ℃, preferably having a viscosity range value of 1 ~ 10,000cP.

The porous body preferably has an open porosity of at least 30% or a total porosity of at least 50%.

The porous body is preferably a calcium phosphate-based material or a gypsum-based material including hydroxy apatite, tricalcium phosphate (TCP) or biphasic calcium phosphate (BCP).

In the step of solidifying or curing the resin, it is preferable to partially solidify or harden the porous body while the porous body is submerged in the resin, and to remove the submerged porous body from the resin to complete the solidification or curing.

In addition, the present invention is to submerge the porous body in a solution unit or partial polymer, or a resin in the molten state to allow the unit or partial polymer, or the resin to penetrate the pores of the porous body, the solution unit or partial polymer penetrated into the porous body Preparing a porous body filled with the cured or solidified resin by curing the polymer by curing with an initiator, light or heat, or solidifying the molten resin by cooling; And mechanically processing the porous body filled with the cured or solidified resin.

The mechanically processing step; preferably, the step of processing by a CAD / CAM method.

In addition, the present invention is to submerge the porous body in a solution unit or partial polymer, or a resin in a molten state to allow the unit or partial polymer, or resin to penetrate the pores of the porous body, the solution unit or a solution state penetrated into the porous body or The porous polymer with improved workability filled with the cured or solidified resin is polymerized by curing the partial polymer with an initiator, light or heat, or solidifying the molten resin by cooling.

Preferably, the porous body is filled with a resin in at least 90% of the open pores.

It is preferable that the porous body is filled with a resin in the range of more than 0 and less than 90% of the open pores.

According to the present invention as described above, it is expected that the effect that the precise processing of the highly porous bone framework material having a high porosity is possible.

In addition, the effect is expected to be processed to minimize the loss of material to the bone material.

In addition, by precisely processing the bone base material, it is possible to increase the consistency of the gum defect structure of patients needing alveolar bone graft, and thus the effect of improving the uniformity of new bone, improved implantability of implanted implant, improved patient satisfaction Is expected.

In addition, since the present invention enables precise processing of the bone framework, there is no need to use granular artificial bones or other substitutes, so that the procedure can be made simple and accurate, and the bone framework can be accurately restored to the planned position. Thus, an easy and accurate operation is expected to work.

In addition, the present invention is expected to produce a very simple operation effect of the manufacturing process of the bone material in a state capable of processing.

1 is a schematic diagram showing a state before and after the resin filling of the porous body produced by one embodiment of the present invention,

Figure 2 is a schematic diagram of the jig provided to test the workability of the porous body produced by one embodiment of the present invention,

Figure 3 (a) is a graph showing the drilling load of the porous body measured in the process of infiltrating the hard wax into the 65 ppi porous body prepared by one embodiment of the present invention, 3 (b) is an embodiment of the present invention A graph showing the drilling load of the porous body measured in the process of infiltrating the soft wax and the hard wax into the 65 ppi porous body manufactured by the example, respectively,

Hereinafter, the present invention will be described in detail with reference to the accompanying drawings and preferred embodiments.

The present invention discloses a porous body in a state in which a high porosity porous body which is easily broken and not easily processed, and manufactured by impregnating a resin so as to reduce material damage during processing, and a manufacturing method and a processing method thereof.

According to the present invention, a resin having a substantial portion or all of the pores of the porous body serves as a support for the porous pore structure, and participates in the processing together with the porous body in the process of processing the porous body, and then dissolves using a solvent or through low temperature heat treatment. The porous body of a desired form can be manufactured easily and correctly by taking out by melt | melting a resin, or heat-scattering.

In FIG. 1, the schematic diagram regarding the state before and after resin filling of the porous body manufactured by one Example of this invention was shown.

The illustrated porous body is a cross-sectional view, (a) shows before the filling material is filled in the open pores, and (b) shows after the filling material is filled in the open pores.

1. The porous body is immersed in a solution unit or partial polymer or a molten resin.

Here, the resin in the solution state or in the molten state can be easily penetrated into the pore structure in the porous body because the viscosity is low enough, and it is more preferable to select and apply the wettability according to the porous material.

In addition, it is to be understood that the monomer or partial polymer is also included in the category of the resin, and the term monomer or partial polymer is separately used in the solution state as described above to distinguish the handling method according to whether the resin is liquid or solid at room temperature. It's just that.

2. Solidify or cure the resin penetrated into the pores in the porous body.

The unit or partial polymer raw material in a solution state is in a liquid state at room temperature, and when curing is required, chemical curing, thermal curing, or photoinitiator is separately added to chemical curing, thermal curing, or photocuring.

Polymerized resins in which the monomer or partial polymer in a solution state are polymerized include both thermoplastic resins and thermosetting resins, and examples thereof include polyethylene (PE), low density polyethylene (LDPE), medium density polyethylene (MDPE), high density polyethylene (HDPE), and polypropylene. (PP), polystyrene (PS), polyvinyl chloride (PVC), ABS resin (acrylonitrile-butadiene-styrene resin), acrylonitrile-styrene resin (ASTNWL, S-AN), polymethyl methacrylate (Methacryl resin, PMMA), polyamide (nylon, PA), polyacetal (POM), polycarbonate (PC), polyethylene terephthalate (PET), polybutylene terephthalate (PBT), modified polyphenylene ether, Fluoroplastics, phenolic resins (PE), urea resins (UF), melamine resins (MF), unsaturated polyester resins (UP), epoxy resins (ER), polyurethanes (PUR), silicone resins (SI), Alkyd resin (ALK).

In addition, the resin in the molten state is present in the solid state or gel state at room temperature, and when properly heated, is changed into the molten state, and when cooled again, retains the original solid phase.

The resin used in the molten state includes a thermoplastic resin, and examples thereof include polyethylene (PE), polyester, polypropylene (PP), polystyrene (PS), polyvinyl chloride (PVC), polymethyl methacrylate (PMMA), Thermosetting resins including polyamide (PA), polycarbonate (PC) or polyethylene terephthalate (PET), polyethylene wax, polypropylenr wax, polyoxyethylene glycol wax, Dental waxes, including halogenated hydrocarbon waxes, hydrogenated waxes or wax esters; Paraffin wax, Liquid paraffin, Microcrystalline wax, Petrolatum, Barnsdah wax, Ozokerite, Montan wax or three Petroleum waxes including resins; Animal waxes including wool wax, soy wax, lanolin or bees wax; Includes Japan wax, Cocoa butter, Carnauba wax, Crystal palm wax, Candellia wax or Ouricury wax Vegetable waxes; Polyethylene wax, Granule Wax, White wax, Gel wax, Polymer of Phthalic Anhydride and Ethylene Glycol, Fischer-Tropsch Wax Synthetic waxes including Fischer-Tropsch wax or Multi wax; Natural derived resins, including Sandrac, Rosin, or Shellac.

The polymer resin in the molten state is preferably high in strength, melting point, glass transition temperature (Tg) at room temperature.

In order to infiltrate the resin into the porous body, the resin must be heated to an appropriate temperature. For example, in the case of polymers of wax, phthalic anhydride and ethylene glycol, they exist in a molten state which exhibits very low viscosities in the temperature range of about 100 to 200 ° C., in particular around 107 ° C., so that the melt is in the porous body. It is easy to penetrate or withdraw from the porous body.

As the unit or partial polymer in the solution state, epoxy, PMMA, or the like is preferably used.

In addition, the molten resin is preferably a polymer of phthalic anhydride and ethylene glycol (Ethylene Glycol), shellac, rosin and the like.

The above resins are generally melted, deposited, and cured in the temperature range of 90 to 150 ° C., and thus can fill pores in the porous body without causing thermal damage to the porous body.

If the resin penetrates more than 90% of the open pores in the porous body, it will be easier to handle the porous body. Therefore, the above 90% has the meaning, but if the process is not complicated, the resin should be processed only in the part requiring processing. Even if the penetration volume is less than 5% of the open pores, if the polymer resin coated with the porous internal structure shows sufficient strength, external stress during CAD / CAM processing can withstand the stress. The porosity may be less than 90%. That is, it may have a range value greater than 0 and less than 90%.

In some cases, the porous body is submerged in the resin to allow the resin to penetrate into the pores of the porous body, but the resin may be withdrawn again in the process of pulling the porous body out of the resin again.

In view of this, it is necessary to divide the steps of solidifying or curing the resin, for example, by cooling or photocuring and thermosetting the porous body submerged in the resin, thereby partially solidifying or curing the resin and completely solidifying the resin. Alternatively, alternative methods may be used to take out the submerged porous body from the resin to complete solidification or curing before curing.

3. Process the porous body.

After filling the above resin into the porous body, the desired shape is obtained through mechanical processing. In the present invention, the bone defects or the shape of the alveolar bone formation needs to be taken by CT (computerized tomography) and imported from CAD software to design the replacement alveolar bone of the shape that needs to be augmented or restored to the patient, this design data According to the computer-controlled processing device (CAM) to process the blank block (blank block-monolith shaped block, porous block bone) of the frame to produce the alveolar bone of the desired design shape. Since the shape of the alveolar bone that needs to be augmented or restored is different for each patient, CAD / CAM processing may be the best in producing alveolar bone that is matched to an individual patient, but mechanical processing is not limited to the above CAD / CAM processing. In some cases, other types of mechanical processing methods such as MAM cutting may be used.

4. Remove the resin.

Once processing of the framework is completed, the above resins must be removed for transplantation, and heat scattered to obtain a pure porous body. This is because the bone substitute is composed of such a pure porous body. If the resin is capable of melting or dissolving, it may be melted instead of heat scattering or dissolved by a solvent to be withdrawn from the porous body. As the solvent, for example, a ketone-based substance such as acetone may be used, and other solvents capable of dissolving the resin may also be used.

The porous body according to one embodiment of the present invention preferably has a scaffold structure and preferably has a porosity of at least 40% or a total porosity of at least 60%. Since this is a desired characteristic of the bone replacement system for the alveolar bone, the present invention can be applied to a porous body which is expected to be damaged in the processing process even if the alveolar bone is not the bone replacement material. In addition, it can be applied regardless of the characteristics of the pores, i.e., whether it is an open or a closed hole, and since the material cannot have a complete closed hole, the ratio of the closed holes becomes to some extent as long as the open holes exist. Regardless of whether it is possible to penetrate the resin, the method according to the present invention may be applied to a porous body predominantly discarded.

Porous bodies as bone substitutes for alveolar bone include calcium phosphate-based or gypsum-based materials including hydroxyapatite, tricalcium phosphate (TCP) or biphasic calcium phosphate (BCP). Although not listed, other possible materials may be sufficient.

In the broadest range, all porous bodies may be targeted, but an appropriate porosity may be determined when the present invention is required, but this may not be uniquely expressed because it depends on the properties of the material.

1. Use of soft wax as resin

In this embodiment, paraffin wax is preferably used as the soft wax for filling the porous body. Soft waxes include Paraffin wax, Liquid paraffin, Microcrystalline wax, Petrolatum, Barnsdah wax, Ozokerite, Montan wax petroleum waxes, including waxes or ceresins; Animal waxes including Wool wax, Soy wax, Lanolin or Bees wax, Japan wax, Cocoa butter, Carnauba wax ( Vegetable waxes including Carnauba wax, Crystal palm wax, Candellia wax or Ouricury wax; Polyethylene wax, Granule Wax, White Wax or Synthetic Wax including Gel Wax may be used.

The soft wax was melted by heating at 100 ° C., and then permeated into the porous body to solidify the resin through a cooling process. Using the porous body thus prepared, a drilling test was performed under the following two conditions.

In CAM machining, roughing is performed on the inner surface and the outer surface, followed by the inner surface finishing process. Drilling test is applied to check the damage of the workpiece in the roughing and finishing process.

Table 1

Evaluation tool and condition

	Tool	diameter	Drilling depth	Drill RPM	Drill feed speed
Test
1	Titanium Processing Tool	2	Min. 4mm	300 RPM	10mm / min
Test
2	Zirconia Processing Tool	2	Max. 10 mm	800 RPM	100mm / min

Schematic diagram of the jig for the test is shown as in FIG.

The porous body fixed by penetrating the soft wax to fix the jig caused a lot of breakage in the processing step. Through this, it was found that the soft wax was faithful to fill the open pores, but did not fully support the porous body during processing. Nevertheless, the use of the soft wax alone has the potential for processing the porous body, it can be seen that it shows a much better processing state than when not using the soft wax. Of course, the damage of the porous body may vary depending on the type of tool and the processing conditions (drill RPM, feed rate).

2. Use of hard wax as resin

As another resin, hard wax was used.

Such hard waxes are polymers of phthalic anhydride and ethylene glycol, polypropylene wax, halogenated hydrocarbon waxes, hydrogenated waxes, and Fischer-Tropsch. And waxes (Fischer-Tropsch wax), multi waxes, and the like. In this embodiment, a crystal wax, which is a polymer of double phthalic anhydride and ethanediol, was used.

In order to further improve the processability of the porous body having a three-dimensional porous structure, it is necessary to fill the empty space inside the porous body to further mitigate the impact on the porous body during processing. However, hard wax should pay more attention than soft wax in terms of permeability. Therefore, it is easy to penetrate into porous body, has high rigidity during processing, and selects and applies materials that can remove solvent to minimize the amount of decomposition products during heat treatment process. shall.

When hard wax is applied, it is easy to penetrate into the porous body by melting when the temperature increases to around 100 ° C, and it is possible to manufacture a porous body that maintains rigidity with hard wax by solidifying when the temperature drops.

Since it was confirmed that there was no volume change when the molten hard wax penetrated and then solidified again, there was no problem caused by expansion and contraction of the hard wax.

The hard wax that has been filled in the pores can be easily removed by acetone, which is a solvent after processing, and the remaining organic matter can be easily removed by a heat treatment process, thereby reducing the process time compared to a process in which the organic material must be removed by a total heat treatment process.

3. Processing of porous body penetrated with hard wax

The porous wax penetrated porous body was subjected to the experiment using the drill RPM 800 and the drill feed rate 200mm / min, which are the harshest conditions that were applied during the machining of the soft wax penetrated porous material.

The porous wax impregnated with hard wax had a good surface edge after processing, and no breakage of the porous structure such as chipping was observed.

After the removal of the hard wax, it was confirmed that the structure of the edge of the machined surface was hardly affected by the tool during the machining and there was no fracture.

Figure 3 (a) is a graph showing the drilling load of the porous body measured in the process of infiltrating the hard wax into the 65 ppi porous body prepared by one embodiment of the present invention, 3 (b) is an embodiment of the present invention It is a graph showing the drilling load of the porous body measured in the process of infiltrating the soft wax and the hard wax into the 65ppi porous body manufactured by the example, respectively.

As shown, when the drilling (Drilling) process is applied, a load of about 17N is applied, which is a very large value compared to about 9.3N when using a soft wax was able to secure a very high rigidity.

Higher loads mean higher strength of the porous body and the wax, ie, the wax is better protecting the support.

Compared to the processability of the pores of the porous body was compared, the processability of the porous body according to the pore size was all so good that the difference can not be confirmed in the step of impregnating the hard wax. On the other hand, after removing the hard wax, it was confirmed that the larger the pore size, the more the structure collapsed at the edge of the processing hole. However, this may be due to the original shape structure of the porous body, although it is also destroyed by the stress concentration during the machining process. This is not a big problem.

Although the present invention has been described based on the preferred embodiments as described above, the scope of protection of the present invention is not to be construed as limiting the scope of the present invention, and the scope of protection of the present invention should be based on the interpretation of the following claims. Will be obvious.

Claims

Preparing a unit or partial polymer in a solution state or a resin in a molten state;

Submerging the porous body in the solution unit or partial polymer or molten resin to allow the unit or partial polymer or resin to penetrate the pores of the porous body; And

Polymerizing or curing the unit or partial polymer penetrated into the porous body by an initiator, light or heat, or solidifying the melt-penetrated resin by cooling;

Process for producing a porous body with improved workability, characterized in that comprising a.
The method of claim 1,

The unit or partial polymer of the solution state is a solution state at room temperature, and a method for producing a porous body improved workability, characterized in that the polymerization cured by the initiator, light or heat.
The method of claim 2,

Polymerized resins in which monomers or partial polymers in solution form are polyethylene (PE), low density polyethylene (LDPE), medium density polyethylene (MDPE), high density polyethylene (HDPE), polypropylene (PP), polystyrene (PS), polychlorinated Vinyl (vinyl chloride resin: PVC), ABS resin (acrylonitrile-butadiene-styrene resin), acrylonitrile-styrene resin (ASTNWL, S-AN), polymethyl methacrylate (methacrylic resin, PMMA), polyamide ( Nylon, PA), Polyacetal (POM), Polycarbonate (PC), Polyethylene Terephthalate (PET), Polybutylene Terephthalate (PBT), Modified Polyphenylene Ether, Fluoroplastics, Phenolic Resin (PE) And urea resins (UF), melamine resins (MF), unsaturated polyester resins (UP), epoxy resins (ER), polyurethanes (PUR), silicone resins (SI), and alkyd resins (ALK). Method for producing a porous body having improved workability.
The method of claim 1,

The method of claim 1, wherein the molten or dissolved resin is solid at room temperature, melted or melted by heating or a solvent, and solidified again by cooling.
The method of claim 4, wherein

The resin in the molten state may be polyethylene (PE), polyester, polypropylene (PP), polystyrene (PS), polyvinyl chloride (PVC), polymethyl methacrylate (PMMA), polyamide (PA), polycarbonate ( PC) or thermosetting resins including polyethylene terephthalate (PET), polyethylene wax, polypropylene wax, polyoxyethylen glycol wax, halogenated hydrocarbon wax, Dental waxes including hydrogenated waxes or wax esters; Paraffin wax, Liquid paraffin, Microcrystalline wax, Petrolatum, Barnsdah wax, Ozokerite, Montan wax or three Petroleum waxes including resins; Animal waxes including wool wax, soy wax, lanolin or bees wax; Includes Japan wax, Cocoa butter, Carnauba wax, Crystal palm wax, Candellia wax or Ouricury wax Vegetable waxes; Polyethylene wax, Granule Wax, White wax, Gel wax, Polymer of Phthalic Anhydride and Ethylene Glycol, Fischer-Tropsch Wax Synthetic waxes including Fischer-Tropsch wax or Multi wax; Method for producing a porous body with improved processability, characterized in that it comprises a naturally derived resin, including Sandrac (Randarac), rosin (Rosin) or Shellac (Shellac).
The method of claim 4, wherein

The molten resin is in a molten state at a temperature of 70 ~ 300 ℃, and has a viscosity range value of 1 ~ 10,000cP characterized in that the processability improved porous body manufacturing method.
The method of claim 1,

And the porous body has an open porosity of at least 30% or a total porosity of at least 50%.
The method of claim 1,

The porous body is a phosphate-based material or gypsum-based material including hydroxyapatite, tricalcium phosphate (TCP) or biphasic calcium phosphate (BCP), or a gypsum-based material. Improved method for producing porous bodies.
The method of claim 1,

In the step of solidifying or curing the resin, it is possible to partially solidify or cure in the state in which the porous body is submerged in the resin, and to improve the processability, characterized in that the solidified or hardened to be taken out by pulling out the submerged porous body from the resin Method for producing a porous body.
Submerging the porous body in a solution unit or partial polymer or molten resin to allow the unit or partial polymer or resin to penetrate into the pores of the porous body, and the unit or partial polymer in solution state penetrated into the porous body is initiated by an initiator, light Or preparing a porous body filled with a cured or solidified resin by curing with heat or by solidifying the molten resin by cooling; And

Mechanically processing the porous body filled with the cured or solidified resin;

Method for processing a porous body improved workability, characterized in that comprising a.
The method of claim 10,

Mechanically processing;

Processing by CAD / CAM method;

A processing method of a porous body having improved workability, characterized in that.
Submerging the porous body in a solution unit or partial polymer or molten resin to allow the unit or partial polymer or resin to penetrate the pores of the porous body, and the solution unit or partial polymer infiltrated into the porous body is initiated by an initiator, A porous body having improved workability, wherein the cured or solidified resin is filled by polymerization or curing by light or heat or by solidifying the molten resin by cooling.
The method of claim 12,

The porous body has improved workability, characterized in that the resin is filled in at least 90% of the open pores (open pore).
The method of claim 12,

The porous body is a porous body with improved workability, characterized in that the resin is filled in the range of more than 0 and less than 90% of the open pores (open pore).