WO2015057583A8 - Treatment of chronic kidney disease with sahps - Google Patents
Treatment of chronic kidney disease with sahps Download PDFInfo
- Publication number
- WO2015057583A8 WO2015057583A8 PCT/US2014/060304 US2014060304W WO2015057583A8 WO 2015057583 A8 WO2015057583 A8 WO 2015057583A8 US 2014060304 W US2014060304 W US 2014060304W WO 2015057583 A8 WO2015057583 A8 WO 2015057583A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- chronic kidney
- kidney disease
- treat
- polypeptides
- disclosed
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Disclosed herein are polypeptides comprising or consisting of a synthetic amphipathic helical peptide or peptide analog, and nucleic acid molecules encoding such polypeptides. Also disclosed herein are methods of using the disclosed polypeptides, analogs, or nucleic acid molecules to treat and/or inhibit chronic kidney disease, as well as to treat and/or inhibit dyslipidemic or vascular disorders, such as methods to treat or prevent cardiovascular disease including atherosclerosis.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361890585P | 2013-10-14 | 2013-10-14 | |
US61/890,585 | 2013-10-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2015057583A1 WO2015057583A1 (en) | 2015-04-23 |
WO2015057583A8 true WO2015057583A8 (en) | 2015-06-18 |
Family
ID=51794993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2014/060304 WO2015057583A1 (en) | 2013-10-14 | 2014-10-13 | Treatment of chronic kidney disease with sahps |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2015057583A1 (en) |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
JPS6023084B2 (en) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | blood substitute |
US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
US4496668A (en) | 1983-08-26 | 1985-01-29 | Hercules Corporated | Cellular thermoset poly(dicyclopentadiene) |
DE3517281A1 (en) | 1985-05-14 | 1986-11-20 | Bayer Ag, 5090 Leverkusen | ELECTROVISCOSE LIQUIDS |
US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
US5091309A (en) | 1986-01-16 | 1992-02-25 | Washington University | Sindbis virus vectors |
CA1257199A (en) | 1986-05-20 | 1989-07-11 | Paul Y. Wang | Preparation containing bioactive macromolecular substance for multi-months release in vivo |
US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
US5217879A (en) | 1989-01-12 | 1993-06-08 | Washington University | Infectious Sindbis virus vectors |
US5993414A (en) | 1998-04-23 | 1999-11-30 | Medtronic, Inc. | Implantable device |
DE19931865A1 (en) | 1999-07-09 | 2001-01-11 | Schopf Maschb Gmbh | Aircraft towing vehicle |
US6436091B1 (en) | 1999-11-16 | 2002-08-20 | Microsolutions, Inc. | Methods and implantable devices and systems for long term delivery of a pharmaceutical agent |
US6527863B1 (en) | 2001-06-29 | 2003-03-04 | Advanced Cardiovascular Systems, Inc. | Support device for a stent and a method of using the same to coat a stent |
ATE469174T1 (en) | 2004-10-15 | 2010-06-15 | Us Gov Health & Human Serv | AMPHIPATHIC HELIX-SHAPED MULTIDOMAIN PEPTIDES AND METHOD FOR USE THEREOF |
US8936787B2 (en) | 2008-04-15 | 2015-01-20 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Peptides promoting lipid efflux |
US20100240598A1 (en) * | 2009-03-16 | 2010-09-23 | The Regents Of The University Of California | Peptides and peptide mimetics to inhibit the onset and/or progression of fibrotic and/or pre-fibrotic pathologies |
WO2011066511A1 (en) | 2009-11-30 | 2011-06-03 | The U.S.A., As Represented By The Secretary Department Of Health And Human Services | Synthetic apoa-1 mimetic amphipathic peptides and methods of use thereof |
-
2014
- 2014-10-13 WO PCT/US2014/060304 patent/WO2015057583A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2015057583A1 (en) | 2015-04-23 |
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