WO2015037750A1 - 다목적 다중영상을 위한 단위블록 및 단위블록을 이용한 다중 모듈 의료용 팬텀 - Google Patents
다목적 다중영상을 위한 단위블록 및 단위블록을 이용한 다중 모듈 의료용 팬텀 Download PDFInfo
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- WO2015037750A1 WO2015037750A1 PCT/KR2013/008155 KR2013008155W WO2015037750A1 WO 2015037750 A1 WO2015037750 A1 WO 2015037750A1 KR 2013008155 W KR2013008155 W KR 2013008155W WO 2015037750 A1 WO2015037750 A1 WO 2015037750A1
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- unit block
- phantom
- block
- medical
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- 238000003384 imaging method Methods 0.000 claims description 17
- 238000000034 method Methods 0.000 claims description 13
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- GLFNIEUTAYBVOC-UHFFFAOYSA-L Manganese chloride Chemical compound Cl[Mn]Cl GLFNIEUTAYBVOC-UHFFFAOYSA-L 0.000 description 3
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- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 description 3
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/58—Testing, adjusting or calibrating thereof
- A61B6/582—Calibration
- A61B6/583—Calibration using calibration phantoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/52—Devices using data or image processing specially adapted for radiation diagnosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/58—Testing, adjusting or calibrating the diagnostic device
- A61B8/587—Calibration phantoms
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- G—PHYSICS
- G09—EDUCATION; CRYPTOGRAPHY; DISPLAY; ADVERTISING; SEALS
- G09B—EDUCATIONAL OR DEMONSTRATION APPLIANCES; APPLIANCES FOR TEACHING, OR COMMUNICATING WITH, THE BLIND, DEAF OR MUTE; MODELS; PLANETARIA; GLOBES; MAPS; DIAGRAMS
- G09B23/00—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes
- G09B23/28—Models for scientific, medical, or mathematical purposes, e.g. full-sized devices for demonstration purposes for medicine
- G09B23/30—Anatomical models
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- A—HUMAN NECESSITIES
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- A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
- A61B6/03—Computed tomography [CT]
- A61B6/032—Transmission computed tomography [CT]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
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- A61B6/48—Diagnostic techniques
- A61B6/481—Diagnostic techniques involving the use of contrast agents
Definitions
- the present invention relates to a unit block and multi-module medical phantom using the unit block for multi-purpose multiple image. More specifically, the present invention relates to the production of unit blocks having a shape and structure capable of filling unit blocks constituting the phantom and a medium necessary for imaging therein, and capable of image quality evaluation, dose measurement, and interventional training.
- MEDICAL PHANTOM is a model that simulates the physical properties of the whole or part of the human body, and is used for various forms and purposes in performance evaluation, diagnostic image quality evaluation, dose measurement, and interventional training and evaluation of diagnostic and therapeutic devices. do.
- the medical phantom can not only be manufactured in various forms so as to be suitable for various sizes and shapes of the imaging device, and eventually, the phantom can only be limited by the characteristics of the device.
- the phantom in a shape similar to the human body, it must be manufactured in a size similar to the human body, and because the medium is put in it, the weight is heavy and many difficulties are in operation.
- the human body can be modeled in a number of ways, especially when simulating the human body with a combination of small voxel units.
- various combinations of voxels can simulate tissues and organs of the human body.
- the above concept may be applied to a medical phantom to configure a phantom in a voxel unit, and the best implementation of the phantom is a phantom using a lego block.
- lego's unit block-in-brick was combined to form a phantom of some form and used to evaluate the performance of an image diagnosis device.
- the block must be put in the container containing the signal source in order to generate a signal source required for imaging.
- the degree of freedom of the block is limited according to the size and shape of the container, and has the same problem as the phantom widely used.
- the lego form has a groin and furrows in the block, so when combined and simply imaged, it has a complex form, which is very disadvantageous for medical use of the image.
- the present invention has been made to solve the above-described problems, and an object thereof is to provide a user with a unit block for multi-purpose multiple images, a multi-module medical phantom using the unit block, and a control method thereof.
- the present invention provides a content for manufacturing a unit block having a form and structure capable of filling a unit block constituting a phantom and a medium necessary for imaging therein, and capable of image quality evaluation, dose measurement, and interventional procedure training. I would like to.
- the plurality of unit blocks is a hexahedral shape
- the first unit block and the inside is empty in the hexahedral shape, the inside is hollow, a plurality of ridges are formed on the top, and includes a second unit block formed with a plurality of furrows coupled to the plurality of ridges at the bottom,
- the medical phantom is determined according to a coupling form of the first unit block and the second unit block, and side surfaces of the first unit block and the second unit block are formed with at least one hole, and the first one of the at least one hole
- a medium is input through one hole, and at least a portion of the medium and the first unit block and the second unit block through the second one of the at least one hole.
- the plurality of ridges are formed in a shape protruding on the top of the second unit block
- the plurality of furrows are formed in a shape recessed at the bottom of the second unit block to be combined with the plurality of ridges.
- the air inside the first unit block and the second unit block may not exist through the second hole.
- the medium input through the first hole may include CuSO 4, MnCl 2, NiCl 2, and a Gd-based medium, an iron oxide-based medium, and a gel-type medium capable of producing a contrast effect.
- the medium input through the first hole may include a material that simulates water, air, bone, contrast media, tissue, and fat for image evaluation in X-ray computed tomography.
- the medium input through the first hole may include positron-emmitting isotopes and gamma-emitting isotopes, which are signal sources of PET and SPECT, which are nuclear medical imaging devices.
- stem cells corresponding to tissues of the human body may be provided inside the first unit block and the second unit block.
- the medical phantom determined according to the combination of the first unit block and the second unit block may be used for multiple purposes, and may be connected to a multi-image device to support multi-imaging.
- the apparatus may further include an image quality evaluation module provided in the first unit block and the second unit block, and the medical phantom may include the spatial resolution, the contrast resolution, the signal to noise ratio, the uniformity, and the like. At least some of the location and accuracy of the section selection and the geometrical accuracy can be evaluated.
- the present invention can provide a user with a unit block for multi-purpose multiple images, a multi-module medical phantom using the unit block, and a control method thereof.
- the present invention is to fill the unit block constituting the phantom and the medium required for the imaging therein, the contents of the production of the unit block having a shape and structure capable of image quality evaluation, dosimetry and interventional treatment training Can provide.
- block-based phantom can be combined in various forms according to the combination of blocks, and can be used for multi-image and multi-purpose, in particular, unit block Is very easy for mass production and very economical because it can be used in many imaging devices.
- FIG. 1 illustrates an example of a radiation dose measuring phantom according to the present invention.
- FIG. 2 shows an example of an exploded perspective view of the radiation dose measuring phantom described in FIG.
- FIG. 3 illustrates various types of medical phantoms associated with the present invention.
- Figure 4 shows a specific example of another type of medical phantom associated with the present invention.
- FIG. 5 illustrates a specific example of modeling a human body in a three-dimensional form in connection with the present invention.
- FIG. 6 illustrates a specific example of modeling a human body using a Lego block.
- FIG. 7 illustrates another specific example of modeling a human body using a Lego block.
- FIG. 8 illustrates a specific example of an MRI T2 image obtained by filling an oxford block with water in accordance with the present invention.
- FIG 9 illustrates a basic form of a unit block proposed by the present invention.
- 10 to 12 show an example of an application form of a unit block proposed by the present invention.
- FIG. 13 illustrates a form of a stem block phantom proposed by the present invention.
- FIG. 14 illustrates a specific form of a stem block phantom applied to multi-purpose multi-images in connection with the present invention.
- 15 to 17 illustrate specific forms of a QA / AC module to which a stem block phantom applied to a multi-purpose multi-image according to the present invention is applied.
- Phantoms are models used as substitutes for the study of biological systems, including the distribution of electromagnetic waves within the body, the investigation and analysis of specific absorption rates (SARs) of human tissues.
- SARs specific absorption rates
- the quantitative evaluation of the electromagnetic wave received by the human body is performed by specific absorption rate, and since it is difficult to actually measure it, a so-called phantom, which is the same as the human body, is made. Estimates based on analysis are performed.
- the phantom needs to have an appearance similar in size to that of the human tissue structure and to have relative permittivity epsilon, conductivity ⁇ and density ⁇ of the human tissue at each measurement frequency.
- the phantom can be used as a model used instead of the human body to determine the amount of radiation received by the human body, and refers to an object used to simulate and measure radiation attenuation, scattering, or distribution of radioactive material in an object. Can be.
- medical phantom is a model that simulates the physical properties of the whole or part of the human body, various forms, various purposes in the performance evaluation of diagnostic and therapeutic devices, medical image quality evaluation, dose measurement, interventional training and evaluation Used as
- FIG. 1 illustrates an example of a radiation dose measurement phantom according to the present invention
- FIG. 2 illustrates an exploded perspective view of the radiation dose measurement phantom described in FIG. 1.
- the linear accelerator 11 is used as a radiation emitting device.
- the phantom 21 is positioned below the vertical portion of the radiation emitting unit 17 in a state where it is placed on the treatment table 19.
- the treatment table 19 constitutes a set with the linear accelerator 11 and is a bed which the patient to treat is exposed on.
- the linear accelerator 11 includes a main body 13 and a rotating gantry 15 rotatably installed on the main body 13.
- a high voltage generator, a microwave generator, and the like are installed, and inside the rotary gantry 15, devices such as an accelerator tube, a magnetic field generator, and a radiation emitter 17 for accelerating electrons are provided. It is provided. The radiation output from the radiation emitter 17 is irradiated to the tumor of the patient lying on the treatment table 19.
- the phantom 21 receives the radiation irradiated downward from the radiation emitting unit 17 in the state set in the vertical lower portion of the radiation emitting unit 17 and receives the dose of the irradiated radiation. Make it understandable.
- the phantom 21 includes one or more base plates 27, a substrate receiving plate 29 in which various kinds of replicas 23 are embedded, a plurality of flat plates 31, and a wedge plate. (25), a thermal fluorescence dosimeter mounting plate (hereinafter referred to as TLD mounting plate) (33 in FIG. 2), an ion chamber mounting plate (39 in FIG. 3), and the like.
- TLD mounting plate thermal fluorescence dosimeter mounting plate
- ion chamber mounting plate 39 in FIG. 3
- Combination examples of the various components described above may vary as the case may be, for example, may have a laminate structure illustrated in FIGS. 4 to 6.
- Reference numeral 51 is an x-ray film.
- the X-ray film 51 represents the energy level of the radiation reaching the surface of the wedge plate 25, the flat plate 31, and the target receiving plate 29 in order to reach the surface thereof.
- the X-ray film 51 is a radiation dose measuring unit for measuring the dose (at the corresponding depth) of the radiation irradiated from the radiation emitting unit 17.
- the radiation dose measuring unit in addition to the X-ray film 51, the TLD mounting plate 33 and the thermoluminescent dosimeter (hereinafter referred to as TLD) (53 in FIG. 2), the ion chamber mounting plate and the same applied thereto An ion chamber is further included.
- the radiation dose measuring unit has the purpose of measuring a dose of radiation at a depth where the radiation dose measuring unit is located.
- the depth at which the radiation dose measuring unit is located depends on the combination example described above, and also what kind of mimetic body 23 is located on the upper portion of the radiation dose measuring unit or not, and the like depends on the case.
- FIG. 2 is an exploded perspective view showing a combination example of the radiation dose measurement phantom according to an embodiment of the present invention.
- the radiation dose measurement phantom 21 includes a base plate 27 having a constant thickness in the form of a square plate, and a TLD stacked on the base plate 27.
- the base plate 27 horizontally supports the TLD mounting plate 33 at a predetermined height from the treatment table 19 while being placed on the treatment table 19 as shown in FIG.
- the base plate 27 is to adjust the distance of the radiation dose measuring unit relative to the radiation emitting unit 17.
- the thickness of the base plate 27 may be made thick or the number of base plates 27 may be increased to narrow the separation distance of the radiation dose measuring unit with respect to the radiation emitter 17.
- Female screw holes 27a are formed at four corners of the base plate 27.
- the female threaded mouth 27a is a groove in which a female thread is formed on an inner circumferential surface thereof, and the male threaded portion 35a of the lower end of the fixed rod 35 is coupled thereto.
- the fixing rod 35 extends vertically in a state coupled to the female screw thread 27a and tightly fixes each component.
- the TLD mounting plate 33 is a rectangular acrylic plate having a predetermined thickness and has five TLD receiving holes 33b extending horizontally therein.
- the TLD accommodation holes 33b have a predetermined diameter and are side by side, and both ends thereof are open to the outside. Of course, the number of the TLD accommodation holes 33b may vary depending on the case.
- acrylic has a tissue density corresponding to the density of general tissue in the body.
- TLD 53 is inserted into the TLD accommodation hole 33b.
- TLD is a dosimeter made of a material having thermofluorescent properties, and may be manufactured in the form of a chip or in powder form. When in powder form it is sealed in a cylindrical capsule.
- a capsule TLD 53 is used. That is, the capsule-type TLD 53 is inserted into the TLD accommodation hole 33b, and then pushed to the center part to be in position.
- a plurality of TLDs 53 may be inserted into one TLD receiving hole 33b, or may be applied only to the selected TLD receiving hole 33b.
- the TLD 53 receives the radiation irradiated from the top in the state of being located in the TLD receiving hole 33b, and can be quantitatively assessed the radiation dose collected by an operator later and exposed through a TLD reader (not shown). do.
- the upper part of the TLD mounting plate 33 is provided with a mimetic accommodation plate 29.
- the mimetic accommodation plate 29 is a hexahedral acryl block having a vertical through hole 29a at four corners, and includes two spaces 29b and 29c therein.
- the spaces 29b and 29c extend horizontally in parallel with each other and are rectangular holes with both ends open to the outside.
- the cross-sectional shape or size of the spaces 29b and 29c may vary depending on the case.
- the spaces 29b and 29c may be empty or filled with the mimetic body 23 according to the simulation target in the body.
- the space portion 29c is left empty.
- cork is known to have a similar tissue density to the lungs
- a teflon having a similar tissue density to bones is inserted.
- the replica 23 may be manufactured in the form of a block, or may be manufactured in the form of a thin plate and then laminated as necessary.
- the mimetic accommodation plate 29 may not be used in some cases.
- the flat plate 31 located above the mimetic accommodation plate 29 is a rectangular acrylic plate having various thicknesses.
- the flat plate 31 serves to control the distance of the target to the radiation emitting unit 17. Therefore, the position or number of sheets of the flat plate 31 may vary as necessary. For example, it may be located between the base plate 27 and the TLD mounting plate 33, or may be installed between the wedge plate 25 and the mimetic accommodation plate 29 as shown. It goes without saying that the through holes 31a are also provided at four corners of the flat plate 31.
- the wedge plate 25 is an acrylic member having a side shape of a right triangle.
- the wedge plate 25 has a horizontal bottom surface and an inclined surface 25b inclined at a predetermined angle with respect to the bottom surface.
- the inclination angle of the inclined surface 25b is about 15 to 30 degrees.
- the wedge plate 25 serves to linearly determine the degree of radiation arrival to the target of different depths. For example, when the radiation is irradiated onto the wedge plate 25 in a state where the X-ray film is positioned below the wedge plate 25, the energy of the radiation is linear to the wedge plate 25 (the thickness of the wedge plate is inclined because the wedge plate is inclined). As it passes downward, the radiation of the smaller and smaller energy is reflected on the X-ray film, and thus the radiation attenuation information about the thickness of the acrylic can be obtained. If the radiation passes through the thick portion of the wedge plate 25, the attenuation rate is so great that less radiation passes through the relatively thin portion.
- the through hole 25a is formed in the four corners of the wedge plate 25.
- the fixed rod 35 is to vertically support each component on the upper portion of the base plate 27 (combination example of each component may vary), the TLD mounting plate 33 and the mimetic accommodation plate (29) and through holes 33a, 29a, 31a, and 25a of the flat plate 31 and the wedge plate 25, and the male threaded portion 35a at the lower end thereof is the female screw hole 27a of the base plate 27. Is fixed to.
- Reference numeral 36 is a nut for fastening the components to each other by coupling to the male screw portion 35a of the upper end of the fixing rod 35.
- Figure 3 illustrates a variety of medical phantom associated with the present invention.
- Figure 4 shows a specific example of another type of medical phantom associated with the present invention.
- the medical phantom can not only be manufactured in various forms to fit the various sizes and shapes of the image diagnosis device, the phantom is inevitably limited to the characteristics of the device.
- the phantom in a shape similar to the human body, it must be manufactured in a size similar to the human body, and because the medium is put in it, the weight is heavy and many difficulties are in operation.
- the human body can be modeled in a number of ways, especially when simulating the human body with a combination of small voxel units.
- various combinations of voxels can simulate tissues and organs of the human body.
- FIG. 5 illustrates a specific example of modeling a human body in a three-dimensional form in connection with the present invention.
- the phantom can be configured in units of voxels, and the best implementation thereof is a phantom using a lego block.
- FIG. 6 illustrates a specific example of modeling a human body using a lego block
- FIG. 7 illustrates another specific example of modeling a human body using a lego block
- FIG. 8 illustrates an oxford block according to the present invention. Specific examples of MRI T2 images obtained after filling with water are shown.
- a unit of the lego block brick of the LEGO was configured to form a phantom of a certain shape and then used to evaluate the performance of the image diagnosis device.
- the block must be put in the container containing the signal source in order to generate a signal source required for imaging.
- the degree of freedom of the block is limited according to the size and shape of the container, and has the same problem as the phantom widely used.
- the lego form has a groin and furrows in the block, so when combined and simply imaged, it has a complex form, which is very disadvantageous for medical use of the image.
- the combination of the small physical size of the combination of the complexity is very large, the relatively large physical size was a disadvantage in that it is disadvantageous to the detailed simulation of human characteristics.
- the present invention provides a unit block for multi-purpose multiple images, a multi-module medical phantom using the unit block, and a control method thereof.
- the present invention provides a method for manufacturing a unit block having a form and structure capable of filling a unit block constituting a phantom and a medium required for imaging therein, and capable of image quality evaluation, dose measurement, and interventional treatment training, and an apparatus using the same. To provide.
- the unit block proposed by the present invention may be manufactured in the form of a cube so as to put a medium therein.
- the basic form of the unit block according to the present invention is a unit block consisting of only a hexahedron and the application form may be a structure in which the blocks can be tightly coupled because there is a ridge (male) on the top of the block and a furrow (female) on the bottom of the block.
- the basic and application unit blocks proposed by the present invention may be configured in various shapes and sizes by combining and combining them.
- a medium such as CuSO4, MnCl2, NiCl2 and Gd-based, iron oxide-based, and gel-type media capable of producing contrast effects may be included in the unit block.
- media such as water, iodine, barium, CaCO3, paraffin and adipose, which can be evaluated by X-ray computed tomography, can be placed.
- Postron-emmitting isotopes which are the signal sources of PET and SPECT And gamma-emitting isotopes.
- multiple combinations of unit blocks enable not only imaging on a single image device but also multiple images on multiple image devices.
- block-based phantom configured in this way can be used for dose evaluation of radiation therapy and temperature measurement of heat therapy.
- image quality evaluation module by adding an image quality evaluation module inside the unit block, spatial resolution, contrast resolution, signal-to-noise ratio, uniformity, position and accuracy of section selection, and geometric accuracy may be evaluated through unit block combinations.
- it can be used together with the phantom used in the existing image quality evaluation to support the acquisition of quality information on the shooting area that the existing phantom could not image.
- FIG 9 illustrates a basic form of a unit block proposed by the present invention.
- FIG. 9 is a block diagram of a basic unit block according to the present invention.
- a denotes a block (phantom) length
- b denotes a block (phantom) width
- c denotes a block (phantom) height
- D means a block (cap) height.
- the interior of the unit block according to the present invention shown in Figure 9 is an empty space is formed in a structure that can be sealed by attaching a medium suitable for the purpose of medical imaging therein.
- the side surface of the unit block according to the present invention has two holes so that the medium can be injected through one hole, and the medium and the internal air injected into the other hole can be released so that no air is generated therein. have.
- 111 means the height of the socket
- 112 means the width of the socket
- 121 means the thickness of the container
- 122 means the fluid of the phantom
- 123 is the inlet of the phantom fluid
- 124 means the height of the block (phantom)
- 125 means the width of the block (phantom) inlet
- 126 means the width of the outlet of the block (phantom).
- 131 means the outlet width of the block (cap)
- 132 means the width of the inlet of the block (cap)
- 133 means the height of the block (cap)
- 134 means pantub fluid
- 135 Means the container material
- 136 means the width of the socket
- 137 means the height of the socket.
- the application unit block is composed of ridges and furrows can be combined and disassembled unit blocks between each other and can be combined in various forms.
- the groin area is in the form of a cube, and the furrows are configured so that the angular area cubes can be attached correctly.
- the inside of the unit block is an empty space and consists of a structure that can be sealed by attaching a medium suitable for the purpose therein.
- the block according to the present invention is a unit block and an application form composed only of a hexahedron, which is a basic form, an application block having a ridge (male) and a furrow (female) at the bottom of the block, and a basic unit block and an application block. It can be a structure that can be combined.
- the basic and application unit blocks proposed by the present invention can be configured in various shapes and sizes by combining and combining them.
- a medium such as CuSO4, MnCl2, NiCl2 and Gd-based, iron oxide-based, and gel-type media capable of producing contrast effects may be included in the unit block.
- media such as water, iodine, barium, CaCO3, paraffin and adipose, which can be evaluated by X-ray computed tomography, can be placed.
- Postron-emmitting isotopes which are the signal sources of PET and SPECT And gamma-emitting isotopes.
- multiple combinations of unit blocks enable not only imaging on a single image device but also multiple images on multiple image devices.
- FIG. 13 illustrates a form of a stem block phantom proposed by the present invention.
- FIG. 13 illustrates contents of CuSO4, MnCl2, NiCl2 and Gd-based, iron oxide-based, and gel-type media capable of producing contrast, such as signals required for magnetic resonance imaging.
- water, iodine, barium, CaCO3, paraffin, adipose, etc. which can be evaluated in X-ray computed tomography, can be added to media, and positron-emmitting, which is a signal source of PET and SPECT, which are nuclear medical imaging devices. You can add isotopes and gamma-emitting isotopes.
- FIG. 14 illustrates a specific form of a stem block phantom applied to multi-purpose multiple images in relation to the present invention.
- FIG. 14 illustrates a basic diagram that enables not only imaging on a single image device but also multiple images on multiple image devices through various combinations of unit blocks.
- the block-based phantom configured as shown in FIG. 14 can be used not only for multiple imaging devices but also for dose assessment of radiation therapy and temperature measurement of heat therapy.
- FIGS. 15 to 17 illustrate specific forms of a QA / AC module to which a stem block phantom applied to multi-purpose multiple images is applied in relation to the present invention.
- FIGS. 15 to 17 show that an image quality evaluation module is added inside a unit block to evaluate spatial resolution, contrast resolution, signal-to-noise ratio, uniformity, location and accuracy of section selection, and geometric accuracy through unit block combination.
- the module schematic is shown.
- the same information as the phantom used for the existing image quality evaluation may be used to obtain quality information on the photographing area that the existing phantom could not image.
- block-based phantoms can be combined in various forms according to the combination of blocks, and can be used for multi-images and multi-purposes. It becomes possible.
- the unit block is very economical because it is very easy for mass production and can be used in various imaging devices.
- the present invention can also be embodied as computer readable codes on a computer readable recording medium.
- Computer-readable recording media include all kinds of recording devices that store data that can be read by a computer system. Examples of computer-readable recording media include ROM, RAM, CD-ROM, magnetic tape, floppy disk, optical data storage, and the like, and may also be implemented in the form of a carrier wave (for example, transmission over the Internet). Include.
- the computer readable recording medium can also be distributed over network coupled computer systems so that the computer readable code is stored and executed in a discrete fashion.
- functional programs, codes, and code segments for implementing the present invention can be easily inferred by programmers in the art to which the present invention belongs.
- the above-described apparatus and method may not be limitedly applied to the configuration and method of the above-described embodiments, but the embodiments may be selectively combined in whole or in part in each of the embodiments so that various modifications may be made. It may be configured.
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Abstract
Description
Claims (9)
- 복수의 단위블록을 이용하여 인체의 적어도 일부를 모델링(modeling) 한 모형인 의료용 팬텀(MEDICAL PHANTOM)에 있어서,상기 복수의 단위블록은,육면체 형상으로 내부가 비어있는 제 1 단위블록; 및상기 육면체 형상으로 내부가 비어있고, 상단에 복수의 이랑이 형성되며, 하단에 상기 복수의 이랑과 결합 가능한 복수의 고랑이 형성된 제 2 단위 블록;을 포함하되,상기 의료용 팬텀은 상기 제 1 단위블록 및 제 2 단위 블록의 결합 형태에 따라 결정되고,상기 제 1 단위블록 및 제 2 단위블록의 측면은 적어도 하나의 구멍이 형성되며,상기 적어도 하나의 구멍 중 제 1 구멍을 통해 매질이 입력되고, 상기 적어도 하나의 구멍 중 제 2 구멍을 통해 상기 매질의 적어도 일부와 상기 제 1 단위블록 및 제 2 단위블록 내부의 공기가 외부로 출력되는 것을 특징으로 하는, 의료용 팬텀.
- 제 1항에 있어서,상기 복수의 이랑은 상기 제 2 단위 블록의 상단에 돌출된 형상으로 형성되고,상기 복수의 고랑은 상기 복수의 이랑과 결합할 수 있도록 상기 제 2 단위 블록의 하단에 함몰된 형상으로 형성되며,상기 제 1 단위블록 및 제 2 단위블록의 내부는 상기 제 2 구멍을 통해 공기가 존재하지 않는 것을 특징으로 하는, 의료용 팬텀.
- 제 1항에 있어서,상기 제 1 구멍을 통해 입력되는 매질은, 자기공명영상에 필요한 H2O, 상기 H2O를 기반으로 하는 CuSO4, MnCl2, NiCl2 및 조영효과를 낼 수 있는 Gd계열 매질, 산화철 계열 매질 및 젤 타입 매질을 포함하는 것을 특징으로 하는, 의료용 팬텀.
- 제 1항에 있어서,상기 제 1 구멍을 통해 입력되는 매질은, X선 컴퓨터 단층촬영에서 영상평가를 할 수 있는 water, air, bone, contrast media, tissue, fat 을 모사하는 물질을 포함하는 것을 특징으로 하는 의료용 팬텀.
- 제 1항에 있어서,상기 제 1 구멍을 통해 입력되는 매질은, 핵의학 영상기기인 PET과 SPECT의 신호원인 positron-emmitting isotopes 및 gamma-emitting isotopes를 포함하는 것을 특징으로 하는, 의료용 팬텀.
- 제 1항에 있어서,상기 제 1 단위블록 및 제 2 단위블록의 내부에는 상기 인체의 조직에 대응하는 줄기세포가 구비되는 것을 특징으로 하는, 의료용 팬텀.
- 제 1항에 있어서,상기 제 1 단위블록 및 제 2 단위 블록의 결합 형태에 따라 결정된 의료용 팬텀은 다중 목적을 위해 사용 가능하고, 다중영상기기와 연결되어 다중영상화를 지원 가능한 것을 특징으로 하는, 의료용 팬텀.
- 제 1항에 있어서,상기 제 1 단위블록 및 제 2 단위블록의 내부에 구비된 영상품질평가 모듈;을 더 포함하고,상기 의료용 팬텀은 상기 영상품질평가 모듈을 이용하여 공간해상도, 대조도 해상도, 신호대잡음비, 균일도, 단면선택의 위치와 정확도 및 기하학적 정확도 중 적어도 일부를 평가할 수 있는 것을 특징으로 하는, 의료용 팬텀.
- 제 1항 내지 제8항 중 적어도 하나에 따른 의료용 팬텀을 이용한 영상진단장치.
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US14/369,813 US20160278734A1 (en) | 2013-09-10 | 2013-09-10 | Unit block for multiple purposes and multiple images, and multi-module medical phantom using unit block |
KR1020147015963A KR101587368B1 (ko) | 2013-09-10 | 2013-09-10 | 다목적 다중영상을 위한 단위블록 및 단위블록을 이용한 다중 모듈 의료용 팬텀 |
PCT/KR2013/008155 WO2015037750A1 (ko) | 2013-09-10 | 2013-09-10 | 다목적 다중영상을 위한 단위블록 및 단위블록을 이용한 다중 모듈 의료용 팬텀 |
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KR101501408B1 (ko) * | 2014-02-13 | 2015-03-12 | 가톨릭대학교 산학협력단 | 다기능 방사선 계측용 장비용 복셀형 블록 팬텀 |
KR101546187B1 (ko) * | 2014-05-30 | 2015-08-21 | 성균관대학교산학협력단 | 팬텀 및 팬텀 시스템 |
US10871591B2 (en) * | 2014-09-26 | 2020-12-22 | Battelle Memorial Institute | Image quality test article set |
KR101943247B1 (ko) * | 2014-12-30 | 2019-01-28 | 한국표준과학연구원 | 다목적, 다중융합영상을 위한 모듈단위 매핑팬텀 |
CN106633926A (zh) * | 2016-12-21 | 2017-05-10 | 南京大学 | 一种自修复超声穿刺用假体材料及其制备方法和应用 |
KR102006666B1 (ko) * | 2017-08-24 | 2019-08-02 | 한국표준과학연구원 | Mri 스캐너의 sar 값을 획득하기 위한 방법 |
KR101982435B1 (ko) * | 2018-01-29 | 2019-05-24 | 한국표준과학연구원 | 의료 영상 길이 측정 표준용 팬텀 |
WO2020006507A1 (en) | 2018-06-29 | 2020-01-02 | The Regents Of The University Of California | Modular phantom for assessment of imaging performance and dose in cone-beam ct |
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KR20080006142A (ko) * | 2006-07-11 | 2008-01-16 | 가톨릭대학교 산학협력단 | 장기모사 팬텀을 갖는 팬텀장치 |
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