WO2015026708A3 - Amelioration of the effects of friedriech's ataxia - Google Patents
Amelioration of the effects of friedriech's ataxia Download PDFInfo
- Publication number
- WO2015026708A3 WO2015026708A3 PCT/US2014/051454 US2014051454W WO2015026708A3 WO 2015026708 A3 WO2015026708 A3 WO 2015026708A3 US 2014051454 W US2014051454 W US 2014051454W WO 2015026708 A3 WO2015026708 A3 WO 2015026708A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- ataxia
- effects
- friedriech
- amelioration
- cis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/201—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having one or two double bonds, e.g. oleic, linoleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The effects of Friedreich's Ataxia are ameliorated by administering to a patient known or suspected of having the disease with essentially free cis Δ9 fatty acid having from 12 to 24 carbon atoms and a single double bond in a cis configuration at the C9 carbon atom. Dosage regimes and kits are also featured.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361867727P | 2013-08-20 | 2013-08-20 | |
US61/867,727 | 2013-08-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2015026708A2 WO2015026708A2 (en) | 2015-02-26 |
WO2015026708A3 true WO2015026708A3 (en) | 2015-11-19 |
Family
ID=52484256
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2014/051454 WO2015026708A2 (en) | 2013-08-20 | 2014-08-18 | Amelioration of the effects of friedriech's ataxia |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2015026708A2 (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007035496A1 (en) * | 2005-09-15 | 2007-03-29 | Edison Pharmaceuticals, Inc. | Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
US20090291092A1 (en) * | 2008-05-22 | 2009-11-26 | Miller Guy M | Treatment of mitochondrial diseases with an erythropoietin mimetic |
EP2272383A1 (en) * | 2009-06-22 | 2011-01-12 | SBAE Industries NV | Composition Comprising Omega-7 and/or Omega-4 Fatty Acids |
US20120040014A1 (en) * | 2010-08-12 | 2012-02-16 | Robert Settineri | LIPID Supplements for Maintaining Health and Treatment of Acute and Chronic Disorders |
-
2014
- 2014-08-18 WO PCT/US2014/051454 patent/WO2015026708A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007035496A1 (en) * | 2005-09-15 | 2007-03-29 | Edison Pharmaceuticals, Inc. | Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers |
US20090291092A1 (en) * | 2008-05-22 | 2009-11-26 | Miller Guy M | Treatment of mitochondrial diseases with an erythropoietin mimetic |
EP2272383A1 (en) * | 2009-06-22 | 2011-01-12 | SBAE Industries NV | Composition Comprising Omega-7 and/or Omega-4 Fatty Acids |
US20120040014A1 (en) * | 2010-08-12 | 2012-02-16 | Robert Settineri | LIPID Supplements for Maintaining Health and Treatment of Acute and Chronic Disorders |
Non-Patent Citations (1)
Title |
---|
NAVARRO, JA: "Altered Lipid Metabolism in a Drosophila Model of Friedreich's Ataxia.", HUMAN MOLECULAR GENETICS., 2010, pages 1 - 13, XP055236237 * |
Also Published As
Publication number | Publication date |
---|---|
WO2015026708A2 (en) | 2015-02-26 |
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