WO2015020969A3 - Analysis of dna methylation in ultra-small clinical samples - Google Patents

Analysis of dna methylation in ultra-small clinical samples Download PDF

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Publication number
WO2015020969A3
WO2015020969A3 PCT/US2014/049626 US2014049626W WO2015020969A3 WO 2015020969 A3 WO2015020969 A3 WO 2015020969A3 US 2014049626 W US2014049626 W US 2014049626W WO 2015020969 A3 WO2015020969 A3 WO 2015020969A3
Authority
WO
WIPO (PCT)
Prior art keywords
ultra
analysis
dna methylation
clinical samples
small clinical
Prior art date
Application number
PCT/US2014/049626
Other languages
French (fr)
Other versions
WO2015020969A2 (en
Inventor
Victor V. Levenson
Anatoliy A. Melnikov
Original Assignee
Us Biomarkers, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Biomarkers, Inc. filed Critical Us Biomarkers, Inc.
Publication of WO2015020969A2 publication Critical patent/WO2015020969A2/en
Publication of WO2015020969A3 publication Critical patent/WO2015020969A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A method for determining a DNA methylation status is provided by this invention.
PCT/US2014/049626 2013-08-06 2014-08-04 Analysis of dna methylation in ultra-small clinical samples WO2015020969A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361862884P 2013-08-06 2013-08-06
US61/862,884 2013-08-06
US201361876050P 2013-09-10 2013-09-10
US61/876,050 2013-09-10

Publications (2)

Publication Number Publication Date
WO2015020969A2 WO2015020969A2 (en) 2015-02-12
WO2015020969A3 true WO2015020969A3 (en) 2015-11-05

Family

ID=52462025

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/049626 WO2015020969A2 (en) 2013-08-06 2014-08-04 Analysis of dna methylation in ultra-small clinical samples

Country Status (1)

Country Link
WO (1) WO2015020969A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090305234A1 (en) * 2005-03-11 2009-12-10 Sven Olek Specific DNAS for Epigenetic Characterisation of Cells and Tissues
US20120252015A1 (en) * 2011-02-18 2012-10-04 Bio-Rad Laboratories Methods and compositions for detecting genetic material

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090305234A1 (en) * 2005-03-11 2009-12-10 Sven Olek Specific DNAS for Epigenetic Characterisation of Cells and Tissues
US20120252015A1 (en) * 2011-02-18 2012-10-04 Bio-Rad Laboratories Methods and compositions for detecting genetic material

Also Published As

Publication number Publication date
WO2015020969A2 (en) 2015-02-12

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