WO2015020367A1 - Diagnostic system and diagnostic device using human sweating response - Google Patents

Diagnostic system and diagnostic device using human sweating response Download PDF

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Publication number
WO2015020367A1
WO2015020367A1 PCT/KR2014/007148 KR2014007148W WO2015020367A1 WO 2015020367 A1 WO2015020367 A1 WO 2015020367A1 KR 2014007148 W KR2014007148 W KR 2014007148W WO 2015020367 A1 WO2015020367 A1 WO 2015020367A1
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WIPO (PCT)
Prior art keywords
light
examinee
perspiration
human body
sweating
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PCT/KR2014/007148
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French (fr)
Korean (ko)
Inventor
최용학
Original Assignee
Choi Yong-Hak
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Publication date
Priority claimed from KR20130092301A external-priority patent/KR101479415B1/en
Priority claimed from KR1020140042334A external-priority patent/KR20150117071A/en
Application filed by Choi Yong-Hak filed Critical Choi Yong-Hak
Publication of WO2015020367A1 publication Critical patent/WO2015020367A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/40Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4029Detecting, measuring or recording for evaluating the nervous system for evaluating the peripheral nervous systems
    • A61B5/4035Evaluating the autonomic nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0064Body surface scanning
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0077Devices for viewing the surface of the body, e.g. camera, magnifying lens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/42Detecting, measuring or recording for evaluating the gastrointestinal, the endocrine or the exocrine systems
    • A61B5/4261Evaluating exocrine secretion production
    • A61B5/4266Evaluating exocrine secretion production sweat secretion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4824Touch or pain perception evaluation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4848Monitoring or testing the effects of treatment, e.g. of medication

Definitions

  • the present invention relates to a diagnosis system and a diagnostic apparatus using a human sweating, more specifically, sweat secreted by a sweating through light irradiation on the skin of a subject without using a coloring reagent chemically reacting to the subject's sweat. Diagnosis of autonomic nervous system, diagnosis of lesions and pain areas of subjects through qualitative and quantitative analysis of system and system for diagnosing sweat perspiration of test subjects by qualitative and quantitative analysis.
  • the present invention relates to a diagnostic apparatus using a human perspiration reaction which can be used without a separate coloring reagent in diagnosing peripheral neuropathy and autonomic neuropathy.
  • the equipment for detecting such abnormalities is a QSART (Quantitative Sudomotor Axon Reflex Test), a skin tissue test using a confocal microscope, and a measuring device to measure nerves. Method, TST, and the like.
  • TST Inconvenient to measure only some nerves or to inject a large amount of drug to the subject for examination.
  • infrared thermography DITI
  • DITI infrared thermography
  • EMG EMG
  • EMG is widely used because of high reproducibility, but only thick coarse nerves can be examined, and the test is inconvenient, expensive, and often unstable in diagnosing autonomic nervous system.
  • the TST method for recognizing the whole body sweat pattern of the entire nerve state in a short time has been widely used.
  • the existing TST method simply installs the device manually in some spaces in the hospital, and it is difficult to popularize because there is a high cost and other inconveniences because it is not systemized.
  • the existing TST device has many advantages, but because it only inspects and diagnoses with a sweating pattern, there are a number of limitations in detecting the amount of sweating for each part other than the pattern and the change of sweating with time. .
  • autonomic dysfunction may be seen in various diseases, and in certain diseases, the autonomic nervous system is selectively invaded to show symptoms, and the anatomical and physiological structures of the autonomic nervous system are very complicated and diverse, and the symptoms may change. Diagnostically difficult to access.
  • the autonomic nervous system can be divided into the sympathetic nervous system and the parasympathetic nervous system, and there are subdivided test methods according to their characteristics, and the autonomic nervous system test can identify damaged components and further determine the treatment method according to the degree of damage and the damaged location. have.
  • Classical heat control test is applied by applying starch powder all over the patient's skin and raising body temperature through warm tea or stove, and then checking the distribution, form and quantity of infinity by the color change of starch. to be.
  • the Gutman Kinizarin Perspiration Test was performed by applying an indicator mixture of kinizarin mixed indicator (Quinizarin 2-6-disulphonic acid, sodium carbonate, and rice starch) to the entire patient's skin. It is a method of measuring the distribution, shape, and quantity of infinity by changing the temperature from red-gray to blue-gray by raising the body temperature using a cabinet.
  • indicator mixture of kinizarin mixed indicator Quinizarin 2-6-disulphonic acid, sodium carbonate, and rice starch
  • the Mayo Clinic presented a heat-controlled sweat test that complements the Gutman Kinizarin sweat test, in which the alizarin red S (Alizarin is proportional to the weight of the skin exposed to the supine position immediately when the patient is not dressed).
  • red S Alizarin is proportional to the weight of the skin exposed to the supine position immediately when the patient is not dressed.
  • red S sodium carbonate and cornstarch mixed indicators are applied to the entire skin and enter the cabinet where the temperature and humidity are maintained to increase the body temperature, and the rate of sweating by heat control on the front surface of the body ( TST%), the distribution, shape, and quantity of infinity.
  • the sweat test by heat control using the medical chamber (TST-100) induces sweating by keeping the user's skin temperature at a constant temperature through a chamber that controls the temperature and humidity after applying reagents to the patient's body. It is a method of acquiring, storing, and inquiring a patient's sweating state in digital form through a camera.
  • thermoregulatory sweat tester TST
  • the coloring reagent 15
  • the sweating reaction Examine the sweating reaction by photographing the deformation pattern according to the chemical reaction of the camera (20).
  • the test subject in the case of the TST using the color developing reagent, the test subject must apply a coloring reagent to the entire subject's skin, and thus the test subject can feel a great sense of rejection. There is a problem.
  • the sweat is secreted according to the perspiration test of the subject during the sweat test, there is a problem that an error occurs in the test by reacting even the coloring reagent of the area where the actual sweat did not occur.
  • the color of the reagent changes, since the change in sweating state is not known thereafter, there is a disadvantage that it is impossible to examine the results of the sweating change over time.
  • a pattern obtained by applying a coloring reagent and sweating is obtained based on (a) the sweating image, and based on the sweating pattern, the condition of the examinee, such as “peripheral neuropathy.
  • (B) Diagnosis of the pattern in which case there is a risk that the coloring reagent in response to sweating may flow or bleed, and diagnosis is made using only a rough pattern in the overall image.
  • additional post-treatment is cumbersome, such as cleaning the coloring reagent on the skin and cleaning the inside of the diagnostic apparatus after sweating.
  • the conventional TST method diagnoses only on the basis of a fixed camera pattern image, the amount of sweating on the side surface or the inclined surface of the body has a problem that it is difficult to accurately capture.
  • the present invention is to solve the problems of the prior art as described above, it is an object of the present invention to provide an sweat diagnosis device that can determine the abnormality of the autonomic nervous system according to the sweating response of the subject through light irradiation to the subject. .
  • test subject feels a great sense of rejection as the reagent is applied to the entire skin of the test subject, and also to solve the problem that the test subject's skin becomes dirty due to the reagent after the test.
  • the perspiration reaction is examined as a deformation pattern according to the chemical reaction of the reagent. Even the reagents in the non-reacted areas are reacted to solve the problem that an error occurs in the test.
  • it is intended to improve the change of sweating over time, for example, a lot of sweating occurs and then decreases and then again to make it possible to examine the results of the sweating changes.
  • the object of the present invention is to measure the sweating reaction caused by the sympathetic nerve reaction under the appropriate stimulus called fever in a comfortable state of the subject, and through the qualitative and quantitative analysis to diagnose the autonomic nervous system, the lesion and pain area of the subject.
  • Diagnosis and functional neurofibers and autonomic neurological disorders to diagnose peripheral neuropathy and autonomic dysplasia to provide a diagnostic device using a human perspiration reaction that can be used without a separate reaction coloring reagent.
  • a diagnostic system using a human sweating response is a system for examining a sweating response of a test subject by heat control, including: temperature control means for inducing a sweating response by raising a body temperature of the testee; Light irradiation means for irradiating light to the skin of the examinee; Light measuring means for collecting the reflected light from the skin of the examinee; And it may include a human diagnostic means for measuring the perspiration response of the subject based on the change in the amount of light or the intensity distribution of the reflected light collected by the light measuring means.
  • the light irradiation means includes a light source unit for generating visible light and irradiating the skin of the examinee
  • the light measuring means includes an optical sensor, a camera, or an optical sensor and a camera for detecting visible light reflected from the skin of the examinee. It includes a light-receiving unit including, can measure the perspiration response of the examinee based on the amount of light to the reflected light of the visible light.
  • the light irradiation means includes a light source unit for generating infrared light and irradiating the skin of the examinee
  • the light measuring means includes an infrared light sensor, an infrared camera, or an infrared ray for detecting infrared light reflected from the skin of the examinee. It includes a light receiving unit including an optical sensor and an infrared camera, it is possible to measure the sweat perspiration of the subject based on the amount of light to the reflected light of the infrared light.
  • the light irradiation means includes a light source unit for generating ultraviolet light and irradiating the skin of the examinee
  • the light measuring means includes an ultraviolet light sensor, an ultraviolet camera, or an ultraviolet ray for sensing the ultraviolet light reflected from the skin of the examinee.
  • It includes a light receiving unit including a light sensor and an ultraviolet camera, it is possible to measure the sweat perspiration of the examinee based on the amount of light to the reflected light or interference light of the infrared light.
  • the light irradiation means and the light measuring means may be integrally formed in one housing.
  • the light irradiation means comprises a plurality of light source units, each light source unit irradiates light to different skin portions of the examinee, and the light measuring means corresponds to the plurality of light source units. It may include a plurality of light receiving portion for collecting the reflected light from the skin.
  • the apparatus further includes a transfer means for transferring the light irradiation means and the light measuring means in a horizontal direction or a vertical direction corresponding to the human body of the examinee, wherein the light irradiation means includes the whole or the skin of the examinee through the transfer means.
  • the light is irradiated while moving a portion, and the light measuring means may collect the reflected light from the skin of the examinee while moving in response to the movement of the light irradiating means.
  • the apparatus further includes rotating means for rotating the light irradiating means and the light measuring means about the human body of the examinee, wherein the light irradiating means rotates around the human body of the examinee to provide light to all or part of the skin of the examinee.
  • the light measuring means may collect the reflected light from the skin of the examinee while rotating in response to the movement of the light irradiation means.
  • the light irradiation means irradiates light to the top, bottom, and side surfaces of the human body of the examinee
  • the light measuring means corresponds to the top, bottom, and side surfaces of the human body of the examinee in response to light irradiation of the light irradiation means.
  • the human body inspection means may measure the three-dimensional sweating state of the human body of the subject.
  • the apparatus further comprises a human body support means for supporting the examinee in a state of lying down on the space, wherein the human body support means includes a transparent material bed, a mesh-shaped mesh bed or a plurality of rods that allow light to pass through at a predetermined interval in parallel. It may include a parallel bar bed spaced apart.
  • the human body support means may be formed of transparent glass or transparent plastic.
  • an antiperspirant diagnostic device that can determine whether the autonomic nervous system abnormality according to the perspiration response of the subject through light irradiation to the subject.
  • the diagnostic apparatus using the human body perspiration reaction it is possible to quickly and accurately diagnose the subject in a comfortable state, such as the daily environment, the display through the diagnosis and character model dummy through the analysis of the characteristics of sweating
  • the lesion, pain area, and pain level of the examinee can be known, so that it is possible to simultaneously pursue convenience and efficiency of the test.
  • TST Thermoregulatory Sweat Tester
  • FIG. 2 is a block diagram of a first embodiment of a diagnostic system using a human body antiperspirant reaction according to an aspect of the present invention
  • Figure 3 shows the principle of measuring the sweating response using light irradiation in the diagnostic system using the human sweating response according to an aspect of the present invention
  • Figure 4 shows an embodiment of a human body support means in a diagnostic system using a human body sweat response according to an aspect of the present invention
  • FIG. 5 is a block diagram of a second embodiment of a diagnostic system using a human body antiperspirant reaction according to an aspect of the present invention.
  • FIG. 6 illustrates an embodiment of a light irradiation means and a light measuring means in a diagnostic system using a human body sweat response according to an aspect of the present invention
  • FIG. 7 is a block diagram of a third embodiment of a diagnostic system using a human sweating response according to an aspect of the present invention.
  • FIG. 8 is a block diagram of a fourth embodiment and a fifth embodiment of a diagnostic system using a human body antiperspirant reaction according to an aspect of the present invention.
  • FIG. 9 is a view for explaining the structure of a diagnostic apparatus using a human body sweat response according to another aspect of the present invention.
  • FIG. 10 is a view for explaining the connection between the components of the diagnostic apparatus using the human body perspiration reaction according to another aspect of the present invention.
  • FIG. 11 is a view for explaining the function of the control unit of the diagnostic device using the human body sweat response according to another aspect of the present invention.
  • FIG. 12 is a flowchart illustrating an operation process of a diagnostic apparatus using a human body sweat response according to another aspect of the present invention.
  • FIG. 13 is a view illustrating an optical system and a driving device such as a camera of a diagnostic device using a human body antiperspirant reaction according to another aspect of the present invention.
  • FIG. 14 is a view for explaining an example displayed on the display unit of the diagnostic device using the body perspiration reaction according to another aspect of the present invention.
  • 15 is a diagram illustrating an example of a sweating image and pattern diagnosis of a conventional TST method.
  • Diagnosis system using the human perspiration reaction a system for examining the perspiration response of the subject by heat control, temperature control means for inducing a perspiration reaction by raising the body temperature of the subject; Light irradiation means for irradiating light to the skin of the examinee; Light measuring means for collecting the reflected light from the skin of the examinee; And it may include a human diagnostic means for measuring the perspiration response of the subject based on the change in the amount of light or the intensity distribution of the reflected light collected by the light measuring means.
  • a method for inspecting the sweating response of the subject according to the reflected light by performing light irradiation on the subject without using a color reagent.
  • Figure 2 shows a block diagram of a first embodiment of a diagnostic system using a human perspiration reaction according to the present invention.
  • perspiration reaction means 200 perspiration reaction means 200, temperature control means 300, human body monitoring means 400, human body support means 500, human diagnostic means (not shown), etc. It may be configured to include.
  • the main characteristic sweat perspiration test means 200 of the present invention may include a light irradiation means 210 and a light measuring means 230, the light irradiation means 210 to the skin of the examinee 10
  • the light 211 is irradiated
  • the light measuring means 230 collects the reflected light 231 which is irradiated onto the skin of the examinee 10 and reflected from the skin.
  • the human diagnosis means (not shown) may measure the sweating response of the examinee 10 based on the collected reflected light 231.
  • the human diagnostic means may include a device such as a PC for analyzing the sweat glands of the examinee 10 according to the characteristics of the reflected light collected by the reflected light 231.
  • the perspiration response is measured by using the difference between the light reflection characteristics of the sweat and non- sweaty skin and the light reflection characteristics of the sweat in the sweaty skin, that is, the irradiated skin is not irradiated and reflected.
  • the difference in light quantity, light intensity, etc. is generated due to the characteristics of interference, refraction, scattering, absorption, reflection, etc. Will be examined.
  • any one of visible light, infrared light, and ultraviolet light may be selectively used as irradiated light to the examinee, and for this, the light irradiating means 210 generates visible light and irradiates the skin of the examinee 10 to the light.
  • An infrared light source unit generating infrared light to irradiate the skin of the test subject 10 or an ultraviolet light source unit generating ultraviolet light and irradiating the skin of the test subject 10, and the light measuring means 230
  • the type of light of the light irradiation means 210 may include a light sensor or camera for visible light, or an IR light sensor or IR camera for infrared light, or a light receiving unit having a UV light sensor or UV camera for ultraviolet light. have.
  • the amount of reflected light or the intensity of light may vary slightly depending on the type of light. As shown in FIG. 3A, the reflected light is collected at a uniform amount of light or light intensity A2.
  • the amount of light or the intensity of the reflected light is changed and collected due to characteristics such as interference of light, refraction, absorption, and reflection on sweat, for example, in FIG.
  • the reflected light reflected by the sweat is more light or intensity (A3) than the reflected light to the non-sweated skin. Can be collected.
  • the reflected light is not secreted due to the characteristic that the infrared light is absorbed by the sweat. It can be collected with less light or light intensity A4 than reflected light to the skin.
  • the ultraviolet light when the ultraviolet light is irradiated to the skin of a subject whose sweat is secreted at a predetermined light intensity or light intensity (A1) in FIG. 3 (d), the ultraviolet light is reflected by sweat in contrast to the skin where the sweat is not secreted. It is more likely to occur and can be collected with more light or intensity (A5) than reflected light for non-sweatened skin, and interference can occur, resulting in more irregular light or light than reflected light for non-sweated skin. Can be collected at an intensity A5.
  • the measurement of the sweating response of the subject by using the point that the optical properties of the sweat and the light properties for the non-secreted skin is different.
  • the light irradiation means 210 irradiates the examinee 10 with at least two different types of light among visible light, infrared light, and ultraviolet light, and the light measuring means 230 emits two or more different kinds of reflected light reflected.
  • the results may be combined to measure the perspiration response.
  • the temperature control means 300 raises the body temperature of the subject 10 to induce a sweating reaction.
  • the temperature adjusting means 300 is provided with a heating wire to increase the temperature in the space where the subject 10 is located.
  • the body temperature of (10) can be raised.
  • the human body monitoring means 400 may optionally include various sensors such as a body temperature sensor, a heart rate monitor, a blood pressure monitor, and the like to be sensed by the human body detecting means 400.
  • the physical state information of 10 may be used as basic information for controlling the degree of increase in body temperature of the examinee 10 in the temperature control means 300, or further, based on the past test record for the specific examinee 10 It may be provided as information for checking the physical condition of the) or temperature control.
  • the human body support means 500 supports the examinee 10 in a lying state on the space, where the human body support means 500 may be formed of various kinds of stable materials capable of supporting the examinee 10, It is more preferable that it is formed of a material which can transmit light.
  • the examinee 10 is lightly lying down toward the front to examine the sweating reaction by only irradiating the upper surface of the examinee 10, and then examines the examinee (although it is possible to perform the perspiration test on the entire subject 10 as a two-time inspection process by examining only the rear surface of the light 10 to examine the perspiration reaction, it is more preferable to look through the following examples.
  • the human body support means 500 is made of a material that can transmit light. It is preferably formed.
  • the human body support means 500 may be formed of a material such as transparent glass or plastic, and furthermore, may be formed in a structure in which light irradiation to the skin of the examinee 10 is not hindered.
  • An embodiment of a human body supporting means in a diagnostic system using the human body antiperspirant reaction according to the present invention is shown.
  • FIG. 4A illustrates a case where the human body support means is a transparent material bed 500a through which light is transmitted, and a bed is formed of glass, transparent plastic, or the like.
  • the bed 500b is formed of a mesh 510b in the form of a mesh on the frame 550b so as not to disturb the light irradiation as much as possible is shown.
  • a plurality of rods 510c are spaced apart at a predetermined interval in parallel to form a bed 500c on the frame 550c so that light irradiation to the skin of the examinee is not disturbed as much as possible. Illustrated.
  • the mesh 510b shown in FIG. 4B and the rod 510c shown in FIG. 4C may be formed of transparent glass or plastic. It may be.
  • FIG. 5 uses the antiperspirant reaction according to the present invention.
  • a schematic diagram of a second embodiment of a diagnostic system is shown.
  • the upper and lower surfaces of the examinee 10 may be irradiated at once to inspect the sweating response to the entire human body of the examinee 10.
  • a human body support means (500b) to support the image is applied to the mesh bed of the mesh type shown in Figure 4 (b).
  • perspiration test means 200b1 and 200b2 are disposed on the upper surface of the examinee 10 to check the sweating response to the upper surface of the examinee 10, and sweat perspiration test means 200c1 and below the lower surface of the examinee 10, respectively. 200c2) was placed.
  • the light irradiation unit 210 and the light measuring unit 230 of the sweating test means 200 are separately configured, but the sweating reaction in the second embodiment of FIG. 5.
  • the inspection means (200b1, 200b2, 200c1, 200c2) is formed integrally on the light irradiation means and the light measuring means on one housing, the diagnostic system using the human body sweat response according to the present invention shown in Figure 6
  • the light irradiation means and the light measuring means by applying the form of the light irradiation means 210a and the light measuring means 230a integrally in one housing 240a as a sweat perspiration test means (200a)
  • the light irradiation means and the light measuring means can be arranged in a narrower space, and the light receiving angle of the reflected light of the light measuring means according to the light irradiation of the light irradiation means does not need to be separately made.
  • a plurality of perspiration reaction inspection means for each zone is configured to divide the human body of the examinee 10 into zones and to collect reflected light by irradiating light in each zone for more accurate perspiration reaction inspection ( 200b1, 200b2, 200c1, 200c2) were disposed.
  • the anti-perspirant test means 200b1, 200b2, 200c1, and 200c2 radiate different types of light to the same skin part of the examinee 10 and collect a plurality of reflected light to collect the reflected light. You can also increase the accuracy.
  • the temperature control means (300a) to induce a sweating response to the upper surface of the subject 10 induces an sweating response to the lower surface of the examinee (10)
  • the sweat test on the upper surface of the test subject 10 and the sweat test on the lower surface of the test subject 10 are not performed separately.
  • the reaction test can be performed.
  • FIG. 7 illustrates a third embodiment of a diagnosis system using the antiperspirant reaction according to the present invention. The schematic diagram is shown.
  • a transfer means for transferring the sweating test means 200d and 200e including light irradiation means and light measuring means in a horizontal direction is formed, and the transfer means is a human body of the examinee 10.
  • Perspiration reaction including a transfer motor (not shown) for moving the horizontal transfer rails 250d and 250e and the anti-perspiration reaction means 200d and 200e formed in the horizontal direction in parallel to the horizontal transfer rails 250d and 250e.
  • the inspection means 200d and 200e may irradiate light along the human body of the examinee 10 in the horizontal direction and collect the reflected light correspondingly.
  • the diagnostic system using the human body sweating reaction may examine the sweating reaction in three dimensions by irradiating light on the upper, lower, and side surfaces of the subject's human body.
  • the diagnostic system using the reaction may further include a vertical conveying means as well as a horizontal conveying means shown in the third embodiment of FIG.
  • sweat perspiration test means 200f, 200g including light irradiation means and light measuring means May be provided with a vertical conveying means for conveying in the vertical direction from the side of the subject 10
  • the vertical conveying means is a vertical conveying rail (250f, 250g) formed in a vertical direction with the human body of the subject 10
  • a transfer motor not shown for moving the sweating test means (200f, 200g) on the vertical transfer rails (250f, 250g), the sweating test means (200f, 200g) of the subject 10 in the vertical direction
  • the light may be irradiated along the human body, and the reflected light may be collected correspondingly.
  • the perspiration test means may be able to more accurately test the perspiration test of the subject by maintaining a constant distance from the human body of the subject, the perspiration reaction according to the present invention shown in Figure 8 (b)
  • the antiperspiration reaction means 200h1 and 200h2 including light irradiation means and light measuring means are rotated about the human body of the examinee 10 to irradiate light and reflect light.
  • the sweat transfer test means 200h1 and 200h2 are transported on the circular transfer rail 250h and the transfer rail 250h formed at the same separation distance around the human body of the examinee 10.
  • an antiperspirant diagnostic device that can determine the abnormality of the autonomic nervous system according to the perspiration response of the examinee through light irradiation to the examinee, in particular using a color reagent It is possible to test for sweating reaction through light irradiation of the examinee's skin, which solves the problem that the examinee feels great rejection as the reagent is applied to the whole skin of the examinee and the subject's skin becomes dirty after the test. The problem of becoming unclean can be solved.
  • the diagnosis of the subject can be performed quickly and accurately in a comfortable state such as a daily environment, and the subject's lesion through the display method displayed on the dummy and the dummy by analyzing the characteristics of sweating.
  • the present invention provides a method for pursuing convenience and efficiency at the same time by providing detailed information on pain, pain area, and pain level.
  • FIG. 9 is a view for explaining the structure of the diagnostic device using the human body sweating according to another aspect of the present invention
  • (a) is a front view
  • (b) is a side view
  • Figure 10 is a component of the diagnostic device using the human sweating response It is a figure explaining the connection between.
  • the chamber 40 is a fastening part for fastening the transparent window 42 and the transparent window 42 which are rotatably attached to the ring 41 formed at the top of the chamber 40 so that the examinee can easily enter and exit the chamber 40. 43), and may further include a chamber support (30) for supporting the chamber (40).
  • a chamber capsule or box
  • Such a chamber is composed of a hook portion and a fastening portion is preferably configured to be easily constructed and to ensure the safety of the examinee entrance and exit. Moreover, it is good also as a conventional sliding structure.
  • the chamber may include a camera, lighting, an optical system, a driving unit, and the like, and the diagnoser visually checks the state of the diagnosis apparatus by configuring the entire chamber as a transparent window or a translucent window as well as the transparent window 42. You can make it possible.
  • the chamber may be made of a whole heat insulating structure.
  • the chamber 40 may further include a human body supporting means 500, which may support the examinee in a state in which the examinee is in a lying state.
  • Temperature control means 300 may be the same as that used in the diagnostic system using the human body perspiration reaction according to an aspect of the present invention, is provided in the chamber 40 to increase the body temperature of the subject to induce a perspiration response will be.
  • the temperature control means 300 may be composed of a plurality of heat generating means, typically a hot air generating device such as a coil-type heater, hot water pipes of the concept of hot water boiler, infrared, near infrared or far-infrared light emitting device and PTC in addition to the above-described heating wire Etc.
  • the antiperspirant test means 200 is provided in the chamber 40 to measure the exothermic and perspiration reactions of the subject to detect the exothermic and perspiration conditions in two or three dimensions.
  • the human body monitoring means 400 includes the chamber 40. It is provided inside to detect the physical condition of the subject in real time. These configurations can be used as the same as those used in the diagnostic system using the human body sweat response according to an aspect of the present invention described above.
  • the perspiration test means 200 is connected to the driving device to detect the heating state as well as the heat state of the examinee in two dimensions and three dimensions can be adjusted in position and angle.
  • the value (data) detected by the sweat perspiration test means 200 is transmitted to the software 700 to analyze the data to diagnose the lesion, pain area and pain degree of the subject.
  • the chamber internal state sensor 600 is a component provided in the chamber 40 to measure the state of the inside of the chamber.
  • the wind direction sensor 600a senses and outputs the air volume and the wind speed in the chamber to the controller 900; It may include a humidity sensor (600b) for sensing the humidity in the chamber and outputs to the control unit 900 and a temperature sensor (600c) for sensing the temperature in the chamber and outputs to the control unit 900, and the other inside the chamber If there is an object may be further provided with a sensor for detecting it.
  • the temperature sensor 600a may measure the center temperature and the surface (skin) temperature of the examinee and the temperature inside the chamber.
  • a temperature sensor is installed in each chamber of the human body and a chamber temperature sensor capable of measuring the temperature inside the chamber (Fig. 10, Ta) and the central temperature of the human body (Fig. 10, Tc) and the skin temperature for each part (Fig. 10, It may include a human body temperature sensor that can measure Ts).
  • the human body temperature sensor is attached to the forehead, armpits, mouth and ears to detect the central temperature of the human body (Fig. 10, Tc) and attached to the leg, torso and face, respectively, the skin temperature of each part (Fig. 10, Ts) It may be made of a skin temperature sensor to detect.
  • the central temperature sensor and the skin temperature sensor may be electronic thermometers or infrared thermometers, and the center temperature and surface temperature of the human body may be measured by contact or noncontact with the forehead, armpits, mouth, ears, legs and torso.
  • the humidity sensor 600b detects humidity in the chamber
  • the wind direction sensor 600c detects air volume and wind speed of the wind in the chamber.
  • infrared cameras, temperature distribution cameras, etc. monitor the air condition of the chamber and the condition of the examinee, and can control the optimal internal chamber conditions.
  • it has a plurality of cameras and illumination, optical system and a driving unit for moving the position / angle of the camera to enable two-dimensional and three-dimensional measurement of the sweating state, it is possible to secure the data to determine the sweating state.
  • the values measured by these sensors are transmitted to the software 700 and control the air in the diagnostic device such as temperature, humidity and wind through each control unit.
  • the chamber internal condition adjusting unit 610 is a component for adjusting the state of the inside of the chamber measured by the chamber internal condition sensor unit 600, and the humidity control unit 610b for controlling the humidity in the chamber and the air volume of the wind in the chamber. It may include a wind controller 610a for adjusting the wind speed and the temperature controller 610c for controlling the temperature in the chamber, and controls to adjust the state of the inside of the chamber measured by the sensor for sensing other necessary conditions It may be further provided.
  • the temperature control unit 600a may use the same or similar device as the above-described temperature control unit 300.
  • the humidity controller 600b may use various types of humidity controllers, for example, a filter-type air purifying humidifier, an ultrasonic humidifier, a heated humidifier, a dehumidifier, and the like using a capillary phenomenon.
  • the wind control unit 600c may use an air conditioner for controlling the air volume and the wind speed in the chamber.
  • the software 700 is a component for diagnosing the lesion, pain area, and pain degree of the examinee by analyzing data measured from the sweating test means 200. That is, the software 700 that can be stored in the computer performs a function of storing and analyzing information received from the chamber in real time in a computer through an interface such as RS-232C and USB, and controlling a camera mounted in the chamber. By taking a picture of the subject at a predetermined time interval and storing it in the database, the sweat pattern of the subject can be analyzed through image processing.
  • the software obtains the sweating state of the 3D surface shape and corrects it with the expression of sweating degree for the 2D area and expresses it as the sweating state value per unit area, constructs a database of sweating state, and stores the data stored therein.
  • the location of sweating, the amount of sweating, and the distribution of sweating are displayed on the dummy of the 3D or 3D human body, and the data of the subject's heat generation temperature, time, input heating temperature, etc. are secured for a plurality of times to identify the subject's heat generation and sweating characteristics.
  • the sweating and fever characteristics which have been identified will enable a personalized measurement for each subject on the basis of retesting later.
  • comparative data according to the degree of healing of the examinee can be obtained.
  • the display 800 is a component that displays the results diagnosed by the software 700 in two or three dimensions using a human body model.
  • control unit 900 is an antiperspirant test means 200, a human body monitoring means 400, the chamber interior It is a component that controls the state control unit 610, software 700 and the display unit 800, and can further control wired and wireless communication means (not shown) that can transmit and receive data between these components Of course.
  • the diagnostic apparatus using the human body perspiration reaction further includes a database unit having the past perspiration response data of the examinee, the control unit 900 using the data if the past perspiration response data is present
  • the temperature adjusting means 300 may be controlled to minimize the measurement time.
  • control unit 900 divides the entire heating area of the examinee into a plurality of small area modules, measures a temperature distribution by mounting a plurality of sensors and cameras at the bottom of each module, and then prevents the local skin surface temperature from rising above a set value. It can be controlled to enable safe diagnosis.
  • FIG. 12 is a flowchart illustrating the operation of the diagnosis apparatus using the human body sweat response according to another aspect of the present invention.
  • the switch when the switch is turned on with the start, it asks whether the examination is to be started, and if the examination is started, the information of the examinee is input.
  • the information of the examinee may be any information that can identify the examinee, such as the resident registration number of the examinee or the control number of the examinee provided when the inspection is requested.
  • the control unit will check the past sweating data.
  • the temperature, humidity and wind in the chamber are adjusted accordingly, and the body temperature of the subject is raised by using a temperature control means to induce a perspiration reaction.
  • the controller may have an advantage of rapidly heating the first sweating characteristic of the examinee and rapidly controlling temperature, humidity, and wind in the chamber.
  • the condition of the chamber is set in advance, and the detection signals of the wind direction sensor, humidity sensor, and temperature sensor are provided and compared with the preset wind, humidity, and temperature data.
  • the control unit increases the human skin temperature and the center temperature to a predetermined temperature so as to increase the body temperature of the subject through the temperature control means to induce a sweating response.
  • the controller collects the skin temperature (FIG. 10, Ts) and the center temperature (FIG. 10, Tc) data of the examinee output from the skin temperature sensor and the central temperature sensor, and periodically reports the temperature data to a computer.
  • the computer collects data on the internal environment, such as the internal temperature of the chamber (FIG. 10, Ta) transmitted from the controller in real time, the skin temperature and the center temperature of the patient, and stores the data in a database, and controls the camera at a set time interval.
  • the upper and lower body sweat patterns are transmitted from the camera and stored in the database.
  • the computer receives the center temperature data transmitted from the control unit to determine whether the center temperature has risen to the set temperature, and when the temperature reaches a preset temperature, for example, 38 to 38.4 ° C., the computer sends a check end command to the control unit.
  • the image of the collected test subject is image-processed and the pattern is quantified and stored in a database.
  • control unit may stop the operation of the temperature control unit, the temperature control unit, the humidity control unit, the wind control unit and other sensors and the camera according to the end of the examination of the computer.
  • FIG. 13 illustrates an optical system such as a camera of a diagnostic apparatus using a perspiration reaction according to another aspect of the present invention, and a driving device to project a moire lattice onto an examinee to detect the change through interference or comparison with a reference lattice pattern.
  • This is an example of an optical system for measuring the degree of sweating in three dimensions, it shows a measuring camera having a drive unit for controlling the position and angle of a portion of the camera for accurate measurement.
  • Diagnosis device using the human perspiration reaction basically secures the data of the sweating state through a plurality of measuring cameras, using a three-dimensional image and a two-dimensional image parallel to the skin surface as the base image of the database.
  • the image of the sweat pattern obtained by applying the coloring reagent it is possible to obtain an image of a surface parallel to the surface of the skin through the drive control of the position and angle of the multiple cameras in the case of the side surface or the inclined surface.
  • the three-dimensional image is obtained by controlling the positions and angles of the plurality of cameras.
  • the three-dimensional image using stereo vision, the three-dimensional measurement image of sweating state through the moiré interference pattern or the interference pattern at the sweat position, and applying the reagent and measuring the sweating pattern It is possible to secure a variety of images suitable for diagnosis, such as stereoscopic images that obtain images or optical three-dimensional height data.
  • the 3D image can be extracted based on the obtained image, and the sweating state of the 2D surface area with respect to the 3D surface shape can be extracted and softwareized.
  • FIG. 14 is a view for explaining an example displayed on a display unit of a diagnostic apparatus using a human sweating response according to another aspect of the present invention.
  • the software 700 obtains perspiration characteristic values, such as perspiration position, perspiration amount, and perspiration distribution, for a three-dimensional surface shape, and then corrects them with an average perspiration characteristic value for a two-dimensional exposed surface area, followed by perspiration position, perspiration amount.
  • perspiration characteristic values such as perspiration distribution on the display unit 800 in which a dummy of two-dimensional or three-dimensional human models is represented. That is, the sweating characteristic may be expressed on the display unit by using a point, color, and / or shape such as the position, quantity, and distribution (pattern) on the 2D or 3D human body model.
  • the sweating characteristic may further comprise a sweating time.
  • the dummy dummy represented in the display unit may be rotated and enlarged or clicked or touched by a click or touch for each part of the display unit or provide detailed sweating information of the corresponding part. That is, when a user clicks or touches a specific position of the dummy dummy represented in the display unit, the image of the specific position can be rotated or enlarged and detailed sweating information of the corresponding position can be displayed.
  • the present invention is composed of a heating means, a sensor, a measuring instrument, an analysis computer, etc., it is possible to systemize, remote communication through communication, etc., it is possible to constitute a relatively inexpensive and convenient device have.
  • systemic techniques for detecting fever and sweating conditions such as sweating amount, sweating time, initial sweating characteristics and temporal change characteristics of sweating, and changes according to temperature and humidity can be used to simplify lesions, pain areas, and pain levels of subjects.
  • the present invention can proceed the test for the sweating reaction by irradiating the skin of the examinee without using a coloring reagent, solve the problem that the subject feels a great sense of rejection by applying the reagent to the entire skin of the subject and after the test Diagnosis system using the human perspiration reaction to solve the problem that the subject's body becomes dirty with reagents, and can quickly and accurately diagnose the subject in a comfortable condition such as a daily environment, and diagnosis through the characterization of sweating and the human body
  • the display method displayed on the dummy can identify the subject's lesion, pain area, and pain level, which can be usefully used in industries such as diagnostic devices using human perspiration, which can simultaneously pursue convenience and efficiency.

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Abstract

The present invention relates to a diagnostic system using a human sweating response, wherein the diagnostic system can progress the test on a human sweating response by irradiating light to the skin of a tested person without using a color developing agent, thereby solving a problem in that the tested person feels the resistance to the application of the reagent to the overall skin, and solving a problem in that the body of the tested person gets dirty and unclean with the reagent; and to a diagnostic device using a human sweating response, wherein the diagnostic device can diagnose a tested person fast and accurately in a relaxed state, such as the day-to-day environment, and recognize lesions, pain areas, and pain degrees of the tested person through diagnosis by analysis of features of sweating and through a display manner in which the displaying is conducted on a human body dummy, thereby pursuing both test convenience and efficiency.

Description

인체 발한 반응을 이용한 진단 시스템 및 진단 장치Diagnostic System and Diagnosis Device Using Human Perspiration
본 발명은 인체 발한 반응을 이용한 진단 시스템 및 진단 장치에 대한 것으로서, 보다 상세하게는 피검사자의 땀에 화학적으로 반응하는 발색시약을 사용하지 않고 피검사자의 피부에 대한 광조사를 통해 발한 반응으로 분비되는 땀에 대한 광학적 특성으로 피검사자의 발한반응을 판단하여 진단하는 시스템 및 피검사자의 발한 반응을 정성적 및 정량적 분석을 통해 자율 신경계 진단, 피검사자의 병소와 통증부위 등을 진단하고 또한 기능 신경섬유 및 자율신경 이상을 검진하여 말초신경병증 및 자율신경이상병증을 진단하는데 별도의 발색시약 없이 사용 가능한 인체 발한 반응을 이용한 진단 장치에 관한 것이다.The present invention relates to a diagnosis system and a diagnostic apparatus using a human sweating, more specifically, sweat secreted by a sweating through light irradiation on the skin of a subject without using a coloring reagent chemically reacting to the subject's sweat. Diagnosis of autonomic nervous system, diagnosis of lesions and pain areas of subjects through qualitative and quantitative analysis of system and system for diagnosing sweat perspiration of test subjects by qualitative and quantitative analysis. The present invention relates to a diagnostic apparatus using a human perspiration reaction which can be used without a separate coloring reagent in diagnosing peripheral neuropathy and autonomic neuropathy.
인체의 미세 신경에 이상이 생기면 운동, 감각, 자율조절계 등에 이상이 오게 되는데, 이러한 이상을 검사하는 장비는 QSART(Quantitative Sudomotor Axon Reflex Test), confocal 현미경을 이용한 피부조직검사, 측정기를 심어 신경을 측정하는 방법, TST 등이 있다.When abnormalities occur in the human body's micro nerves, abnormalities occur in movements, sensations, and self-regulatory systems.The equipment for detecting such abnormalities is a QSART (Quantitative Sudomotor Axon Reflex Test), a skin tissue test using a confocal microscope, and a measuring device to measure nerves. Method, TST, and the like.
TST를 제외한 대다수의 방법들은 일부의 신경만을 측정할 수 있거나 검사를 위해 피검사자에게 다량의 약물을 투여해야만 하는 불편함이 있어왔다. 또한 현재 많이 보급되어 있는 적외선 체열 촬영기(DITI)는 인체의 피부 온도를 열화상으로 감지하여 체온 분포도를 측정하여 통증이나 병소부위, 정상부위의 진단을 열화상을 통해 출력하고 있으나, 피검사자 상태변화 예컨대, 환경, 식사 또는 약물 등에 따라 정확성과 재현 반복성이 떨어지는 단점이 있다. 또한 근전도 검사기(EMG)의 경우 재현성이 높아 널리 사용되고 있으나, 굵은 유수 신경만이 검사 가능하고, 검사가 불편하고 고가이며 자율신경계 진단에 있어서는 불안정한 결과를 얻는 경우가 많다.Most of the methods except TST have been inconvenient to measure only some nerves or to inject a large amount of drug to the subject for examination. In addition, infrared thermography (DITI), which is widely used, detects the skin temperature of the human body as a thermal image and measures the temperature distribution, and outputs a diagnosis of pain, lesion area, and normal area through thermal image. However, there is a disadvantage that the accuracy and repeatability are poor depending on the environment, the meal or the drug. In addition, EMG (EMG) is widely used because of high reproducibility, but only thick coarse nerves can be examined, and the test is inconvenient, expensive, and often unstable in diagnosing autonomic nervous system.
이에 따라 전체 신경 상태를 빠른 시간 안에 전신 발한 패턴을 인식하는 TST 방법이 많이 사용되고 있다. 그러나 기존의 TST 방법은 병원 내에 일부 공간에 장치를 수작업으로 간이 설치하여, 시스템화되어 있지 못한 관계로 고비용과 기타 불편이 발생하는 점이 있어 대중화가 이루어지기 어려운 실정이다. 또한 기존의 TST 기기는 많은 장점이 있음에도 현재 발한 패턴만을 가지고 검사하고 진단하므로, 패턴 이외의 각 부위별 발한 양, 시간에 따른 발한의 변화 등을 감지해 내기에는 여러 제약이 많이 존재한다는 단점이 있다. Accordingly, the TST method for recognizing the whole body sweat pattern of the entire nerve state in a short time has been widely used. However, the existing TST method simply installs the device manually in some spaces in the hospital, and it is difficult to popularize because there is a high cost and other inconveniences because it is not systemized. In addition, the existing TST device has many advantages, but because it only inspects and diagnoses with a sweating pattern, there are a number of limitations in detecting the amount of sweating for each part other than the pattern and the change of sweating with time. .
한편, 자율신경 기능장애는 다양한 질환에서 보일 수 있는데, 특정질환에서는 자율신경계를 선택적으로 침범하여 증상을 나타내며, 자율신경계의 해부학적, 생리학적 구조가 매우 복잡하고 다양하면서 증상이 변화무쌍하게 변할 수 있어 진단적으로 접근이 난해하다.On the other hand, autonomic dysfunction may be seen in various diseases, and in certain diseases, the autonomic nervous system is selectively invaded to show symptoms, and the anatomical and physiological structures of the autonomic nervous system are very complicated and diverse, and the symptoms may change. Diagnostically difficult to access.
자율신경계는 교감신경계와 부교감신경계로 나눌 수 있는데, 이들의 특징에 따라 세분화된 검사방법들이 있으며, 자율신경계 검사를 통하여 손상된 성분들을 파악할 수 있고 나아가서 손상 정도와 손상된 위치에 따른 치료 방식을 판단할 수 있다.The autonomic nervous system can be divided into the sympathetic nervous system and the parasympathetic nervous system, and there are subdivided test methods according to their characteristics, and the autonomic nervous system test can identify damaged components and further determine the treatment method according to the degree of damage and the damaged location. have.
자율신경계 감사 방법으로서 열 조절에 의한 발한반응 검사에 대한 연구가 활발하게 진행되고 있는데, 열 조절에 의한 발한반응 검사는 체온 상승에 대한 국소적 땀 분비를 정성적으로 측정하는 것으로서,(해리슨내과학편찬위원회 2003) 자율신경 기능장애를 신체 앞 표면에서 열 조절에 의한 발한반응률(TST%), 무한증의 분포, 형태, 양을 계산하여 그 증상을 확인하고, 심한 정도를 정량적 기록하며, 자율신경계 각각의 기능 이상 유무 등을 파악하는 검사이다.As an autonomic nervous system audit method, research on the sweating test by heat regulation is actively conducted. The sweating test by heat regulation is a qualitative measure of local sweat secretion in response to a rise in body temperature. Committee 2003) Calculate the symptoms of autonomic dysfunction by calculating the rate of sweating (TST%), distribution, form, and amount of independence on the front surface of the body, and quantitatively record the severity of the autonomic nervous system. This is to check whether there is a malfunction or not.
열 조절에 의한 발한반응 검사는 다양한 검사방법이 있는데, 종래 열 조절에 의한 발한반응 검사의 일부를 정리하면 다음과 같다.There are various test methods for the sweating test by heat control. The part of the sweating test by conventional heat control is summarized as follows.
1) 고전적인 열 조절에 의한 발한반응 검사1) Perspiration test by classical heat control
고전적인 열 조절에 의한 발한반응 검사는, 녹말가루를 환자의 피부 전체에 바르고 따뜻한 차나 난로 등을 통해 체온을 상승시킨 후에 녹말의 색깔 변화로 무한증의 분포, 형태, 양을 도식화하여 검사하는 방식이다.Classical heat control test is applied by applying starch powder all over the patient's skin and raising body temperature through warm tea or stove, and then checking the distribution, form and quantity of infinity by the color change of starch. to be.
2) 구트만 키니자린 발한반응 검사(Guttmann quinizarin sweat test)2) Gutmann quinizarin sweat test
구트만 키니자린 발한반응 검사는, 키니자린 혼합지시약(키니자린(Quinizarin 2-6-disulphonic acid), 탄산 나트륨(sodium carbonate) 및 쌀 녹말(rice starch)을 혼합한 지시약을 환자의 피부 전체에 바르고 캐비닛(sweat cabinet)을 이용하여 체온을 상승시켜 지시약이 적회색(red-gray)에서 청회색(blue-gray)으로 변하는 것을 통해 무한증의 분포, 형태, 양을 측정하는 방식이다.The Gutman Kinizarin Perspiration Test was performed by applying an indicator mixture of kinizarin mixed indicator (Quinizarin 2-6-disulphonic acid, sodium carbonate, and rice starch) to the entire patient's skin. It is a method of measuring the distribution, shape, and quantity of infinity by changing the temperature from red-gray to blue-gray by raising the body temperature using a cabinet.
3) 메이요 클리닉에서 개발한 열 조절에 의한 발한반응 검사3) Perspiration test by heat control developed by Mayo Clinic
메이요 클리닉에서 구트만 키니자린 발한반응 검사를 보완한 열 조절에 의한 발한반응 검사 방법을 제시하였는데, 환자가 옷을 입지 않은 상태에서 바로 누운자세로 노출된 피부에 체중에 비례하여 알리자린 적색 S(Alizarin red S), 탄산 나트륨(sodium carbonate) 및 녹말가루(cornstarch)를 혼합한 지시약을 피부 전체에 바르고 일정 온도와 습도가 유지되는 캐비닛에 들어가서 체온을 상승시켜 신체 앞 표면에서 열조절에 의한 발한반응률(TST%), 무한증의 분포, 형태, 양을 계산하는 방식이다.The Mayo Clinic presented a heat-controlled sweat test that complements the Gutman Kinizarin sweat test, in which the alizarin red S (Alizarin is proportional to the weight of the skin exposed to the supine position immediately when the patient is not dressed). red S), sodium carbonate and cornstarch mixed indicators are applied to the entire skin and enter the cabinet where the temperature and humidity are maintained to increase the body temperature, and the rate of sweating by heat control on the front surface of the body ( TST%), the distribution, shape, and quantity of infinity.
4) 의료용 챔버를 이용한 열 조절에 의한 발한반응 검사4) Perspiration test by heat control using medical chamber
의료용 챔버(TST-100)를 이용한 열 조절에 의한 발한반응 검사는 환자의 몸에 시약을 바른 후 온도와 습도 조절하는 챔버를 통해 사용자의 피부온도를 일정 온도로 유지토록 하여 발한을 유도하고 장착된 카메라를 통해 환자의 발한 상태를 디지털(digital)의 형태로 획득, 저장, 조회하는 방식이다.The sweat test by heat control using the medical chamber (TST-100) induces sweating by keeping the user's skin temperature at a constant temperature through a chamber that controls the temperature and humidity after applying reagents to the patient's body. It is a method of acquiring, storing, and inquiring a patient's sweating state in digital form through a camera.
이와 같은 발한반응 검사 방식은 모두 피검사자의 피부에 발색시약을 바르고 발한 반응을 유도하여 분비되는 땀에 대한 발색시약의 화학적 반응에 따른 변형 패턴으로서 발한반응을 검사하는 방식으로서, 예시적으로 도 1에 도시된 종래기술에 따른 발한진단기기(TST; Thermoregulatory Sweat Tester)의 구성도를 참조하면, 땀과 화학적으로 반응하는 발색시약(15)을 피검사자(10)의 피부 전체에 바르고 발한 반응에 의해 발색시약의 화학적 반응에 따른 변형 패턴을 카메라(20) 등으로 촬영하여 발한반응을 검사한다.All of these antiperspirant test methods are applied to the subject's skin and induce a perspiration reaction to examine the perspiration reaction as a modification pattern according to the chemical reaction of the colorant to the secreted sweat. Referring to the schematic diagram of the thermoregulatory sweat tester (TST) according to the prior art shown, the coloring reagent (15) is applied to the entire skin of the subject (10) and chemically reacts with the sweat and the coloring reagent by the sweating reaction Examine the sweating reaction by photographing the deformation pattern according to the chemical reaction of the camera (20).
이와 같이 발색 시약을 이용하는 발한진단기기(TST)의 경우, 피검사자의 피부 전체에 발색시약을 발라야 하므로 피검사자는 이에 대한 거부감을 크게 느낄 수 있으며, 나아가서 검사 후 피검사자의 피부는 발색시약으로 더러워진 불결한 상태가 된다는 문제점이 있다.As described above, in the case of the TST using the color developing reagent, the test subject must apply a coloring reagent to the entire subject's skin, and thus the test subject can feel a great sense of rejection. There is a problem.
특히, 발한반응 검사 중 피검사자의 발한 반응에 따라 분비되는 땀이 흘러 실제 땀이 발생하지 않은 부위의 발색시약까지도 반응함으로써 검사에 오류가 발생되는 문제점이 있다. 또한 발한반응이 한번 일어나서 시약의 색깔이 변화하면 그 이후에는 발한상태의 변화를 알 수 없기 때문에, 시간에 따른 발한 변화 결과의 검사는 불가능하다는 단점이 있다.In particular, the sweat is secreted according to the perspiration test of the subject during the sweat test, there is a problem that an error occurs in the test by reacting even the coloring reagent of the area where the actual sweat did not occur. In addition, once the sweating reaction occurs, the color of the reagent changes, since the change in sweating state is not known thereafter, there is a disadvantage that it is impossible to examine the results of the sweating change over time.
또한 종래의 TST 방식은 도 15에 도시된 바와 같이 발색 시약을 바르고 발한이 이루어진 영상인 (a)발한 영상을 기초로 발한 패턴을 얻고, 이러한 발한 패턴을 근거로 피검사자의 병증, 예컨대 “말초신경병증”의 (b) 패턴 진단을 내리는 것인데, 이 경우 발한에 반응한 발색 시약이 흐르거나 번질 우려가 있고 전체적인 영상에서 개략적인 패턴만을 이용해 진단하기 때문에 미세 부위별 병증의 진단에는 제약이 많고, 발한이 초기에 많이 일어나는 경우 후기의 발한은 영상으로 잘 찾기 어려운 단점이 있다. 또한, 발한 진단 이후 피부에서 발색 시약을 닦고 진단기 내부를 청소하는 등 부가적인 후처리 작업이 번거롭게 이루어지는 단점이 있다. In addition, in the conventional TST method, as shown in FIG. 15, a pattern obtained by applying a coloring reagent and sweating is obtained based on (a) the sweating image, and based on the sweating pattern, the condition of the examinee, such as “peripheral neuropathy. (B) Diagnosis of the pattern, in which case there is a risk that the coloring reagent in response to sweating may flow or bleed, and diagnosis is made using only a rough pattern in the overall image. In the early stages, a lot of late sweating is difficult to find well by video. In addition, there is a disadvantage that additional post-treatment is cumbersome, such as cleaning the coloring reagent on the skin and cleaning the inside of the diagnostic apparatus after sweating.
또한 종래의 TST 방식은 고정된 카메라 패턴 영상을 기초로만 진단하기 때문에 신체의 옆면이나 경사면에서의 발한 양은 정확하게 잡아내기 어려운 문제점이 있었다.In addition, since the conventional TST method diagnoses only on the basis of a fixed camera pattern image, the amount of sweating on the side surface or the inclined surface of the body has a problem that it is difficult to accurately capture.
본 발명은 상술한 바와 같은 종래 기술의 문제점을 해결하고자 하는 것으로서, 피검사자에 대한 광조사를 통해 피검사자의 발한반응에 따른 자율신경계의 이상 여부를 판단할 수 있는 발한진단기기를 제공하는 것을 목적으로 한다.The present invention is to solve the problems of the prior art as described above, it is an object of the present invention to provide an sweat diagnosis device that can determine the abnormality of the autonomic nervous system according to the sweating response of the subject through light irradiation to the subject. .
특히, 피검사자의 피부 전체에 시약을 바름에 따라 피검사자가 거부감을 크게 느끼는 문제점을 해결하고 또한 검사 후 피검사자의 피부가 시약으로 더러워진 불결한 상태가 되는 문제점을 해결하고자 한다.In particular, it is intended to solve the problem that the test subject feels a great sense of rejection as the reagent is applied to the entire skin of the test subject, and also to solve the problem that the test subject's skin becomes dirty due to the reagent after the test.
나아가서 발한반응 검사를 위해 피검사자의 피부에 시약을 바르고 발한 반응을 유도하여 시약의 화학적 반응에 따른 변형 패턴으로서 발한반응을 검사함으로써 검사 중 피검사자의 발한 반응에 따라 분비되는 땀이 흘러 실제 땀이 발생하지 않은 부위의 시약까지도 반응되어 검사에 오류가 발생되는 문제점을 해결하고자 한다. 또한, 시간에 따른 발한 변화, 예컨대 발한이 많이 일어나다가 줄어들었다가 다시 많이 나는 등의 발한 상태 변화의 결과 검사를 가능하게 하는 개선을 하고자 한다.Furthermore, by applying a reagent to the subject's skin for the perspiration test and inducing a perspiration reaction, the perspiration reaction is examined as a deformation pattern according to the chemical reaction of the reagent. Even the reagents in the non-reacted areas are reacted to solve the problem that an error occurs in the test. In addition, it is intended to improve the change of sweating over time, for example, a lot of sweating occurs and then decreases and then again to make it possible to examine the results of the sweating changes.
또한 본 발명의 목적은 피검사자가 편안한 상태에서 발열이라고 하는 적절한 자극을 받아 교감신경의 반응으로 발생하는 발한 반응을 측정하고 이를 정성적 및 정량적 분석을 통해 자율 신경계 진단, 피검사자의 병소와 통증부위 등을 진단하고 또한 기능 신경섬유 및 자율신경 이상을 검진하여 말초신경병증 및 자율신경이상병증을 진단하는데 별도의 반응 발색 시약 없이 사용 가능한 인체 발한 반응을 이용한 진단 장치을 제공하고자 한다.In addition, the object of the present invention is to measure the sweating reaction caused by the sympathetic nerve reaction under the appropriate stimulus called fever in a comfortable state of the subject, and through the qualitative and quantitative analysis to diagnose the autonomic nervous system, the lesion and pain area of the subject. Diagnosis and functional neurofibers and autonomic neurological disorders to diagnose peripheral neuropathy and autonomic dysplasia to provide a diagnostic device using a human perspiration reaction that can be used without a separate reaction coloring reagent.
상기 기술적 과제를 달성하고자 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템은, 열 조절에 의한 피검사자의 발한반응을 검사하기 위한 시스템으로서, 피검사자의 체온을 상승시켜 발한 반응을 유도하기 위한 온도조절수단; 상기 피검사자의 피부로 광을 조사하는 광 조사수단; 상기 피검사자의 피부로부터 반사 광을 수집하는 광 측정수단; 및 상기 광 측정수단에서 수집한 반사 광의 광량 변화 또는 광강도 분포를 기초로 상기 피검사자의 발한 반응을 측정하는 인체 진단수단을 포함할 수 있다.In order to achieve the above technical problem, a diagnostic system using a human sweating response according to the present invention is a system for examining a sweating response of a test subject by heat control, including: temperature control means for inducing a sweating response by raising a body temperature of the testee; Light irradiation means for irradiating light to the skin of the examinee; Light measuring means for collecting the reflected light from the skin of the examinee; And it may include a human diagnostic means for measuring the perspiration response of the subject based on the change in the amount of light or the intensity distribution of the reflected light collected by the light measuring means.
여기서 상기 광 조사수단은, 가시광을 발생시켜 상기 피검사자의 피부로 조사하는 광원부를 포함하고, 상기 광 측정수단은, 상기 피검사자의 피부로부터 반사되는 가시광을 감지하는 광센서, 카메라 또는 광센서와 카메라를 포함하는 수광부를 포함하며, 상기 가시광의 반사광에 대한 광량을 기초로 상기 피검사자의 발한 반응을 측정할 수 있다.Here, the light irradiation means includes a light source unit for generating visible light and irradiating the skin of the examinee, and the light measuring means includes an optical sensor, a camera, or an optical sensor and a camera for detecting visible light reflected from the skin of the examinee. It includes a light-receiving unit including, can measure the perspiration response of the examinee based on the amount of light to the reflected light of the visible light.
또는 상기 광 조사수단은, 적외선광을 발생시켜 상기 피검사자의 피부로 조사하는 광원부를 포함하고, 상기 광 측정수단은, 상기 피검사자의 피부로부터 반사되는 적외선광을 감지하는 적외선 광센서, 적외선 카메라 또는 적외선 광센서와 적외선 카메라를 포함하는 수광부를 포함하며, 상기 적외선광의 반사광에 대한 광량을 기초로 상기 피검사자의 발한 반응을 측정할 수 있다.Alternatively, the light irradiation means includes a light source unit for generating infrared light and irradiating the skin of the examinee, and the light measuring means includes an infrared light sensor, an infrared camera, or an infrared ray for detecting infrared light reflected from the skin of the examinee. It includes a light receiving unit including an optical sensor and an infrared camera, it is possible to measure the sweat perspiration of the subject based on the amount of light to the reflected light of the infrared light.
또는 상기 광 조사수단은, 자외선광을 발생시켜 상기 피검사자의 피부로 조사하는 광원부를 포함하고, 상기 광 측정수단은, 상기 피검사자의 피부로부터 반사되는 자외선광을 감지하는 자외선 광센서, 자외선 카메라 또는 자외선 광센서와 자외선 카메라를 포함하는 수광부를 포함하며, 상기 적외선광의 반사광 또는 간섭광에 대한 광량을 기초로 상기 피검사자의 발한 반응을 측정할 수 있다.Alternatively, the light irradiation means includes a light source unit for generating ultraviolet light and irradiating the skin of the examinee, and the light measuring means includes an ultraviolet light sensor, an ultraviolet camera, or an ultraviolet ray for sensing the ultraviolet light reflected from the skin of the examinee. It includes a light receiving unit including a light sensor and an ultraviolet camera, it is possible to measure the sweat perspiration of the examinee based on the amount of light to the reflected light or interference light of the infrared light.
바람직하게는 상기 광 조사수단와 상기 광 측정수단는 하나의 하우징에 일체형으로 형성될 수 있다.Preferably, the light irradiation means and the light measuring means may be integrally formed in one housing.
보다 바람직하게는 상기 광 조사수단은, 복수개의 광원부를 포함하고, 각각의 광원부는 상기 피검사자의 서로다른 피부 부위로 광을 조사하며, 상기 광 측정수단은, 상기 복수개의 광원부에 대응하여 상기 피검사자의 피부로부터 반사 광을 수집하는 복수개의 수광부를 포함할 수 있다.More preferably, the light irradiation means comprises a plurality of light source units, each light source unit irradiates light to different skin portions of the examinee, and the light measuring means corresponds to the plurality of light source units. It may include a plurality of light receiving portion for collecting the reflected light from the skin.
나아가서 상기 피검사자의 인체에 대응하여 상기 광 조사수단과 상기 광 측정수단을 수평 방향 또는 수직 방향으로 이송시키는 이송수단을 더 포함하며, 상기 광 조사수단은 상기 이송수단을 통해 상기 피검사자의 피부의 전체 또는 일부분을 이동하면서 광을 조사하고, 상기 광 측정수단은 상기 광 조사수단의 이동에 대응하여 이동하면서 상기 피검사자의 피부로부터 반사 광을 수집할 수도 있다.The apparatus further includes a transfer means for transferring the light irradiation means and the light measuring means in a horizontal direction or a vertical direction corresponding to the human body of the examinee, wherein the light irradiation means includes the whole or the skin of the examinee through the transfer means. The light is irradiated while moving a portion, and the light measuring means may collect the reflected light from the skin of the examinee while moving in response to the movement of the light irradiating means.
또한 상기 피검사자의 인체를 중심으로 상기 광 조사수단과 상기 광 측정수단를 회전시키는 회전수단을 더 포함하며, 상기 광 조사수단은 상기 피검사자의 인체를 중심으로 회전하면서 상기 피검사자의 피부의 전체 또는 일부분에 광을 조사하고, 상기 광 측정수단은 상기 광 조사수단의 이동에 대응하여 회전하면서 상기 피검사자의 피부로부터 반사 광을 수집할 수도 있다.The apparatus further includes rotating means for rotating the light irradiating means and the light measuring means about the human body of the examinee, wherein the light irradiating means rotates around the human body of the examinee to provide light to all or part of the skin of the examinee. The light measuring means may collect the reflected light from the skin of the examinee while rotating in response to the movement of the light irradiation means.
한걸음 더 나아가서 상기 광 조사수단은 상기 피검사자의 인체의 상면, 하면 및 측면으로 광을 조사하고, 상기 광 측정수단은 상기 광 조사수단의 광 조사에 대응하여 상기 피검사자의 인체의 상면, 하면 및 측면의 피부로부터 반사 광을 수집하며, 상기 인체 검사수단은 상기 피검사자의 인체에 대하여 3차원적으로 발한 상태를 측정할 수도 있다.Further, the light irradiation means irradiates light to the top, bottom, and side surfaces of the human body of the examinee, and the light measuring means corresponds to the top, bottom, and side surfaces of the human body of the examinee in response to light irradiation of the light irradiation means. Collecting reflected light from the skin, the human body inspection means may measure the three-dimensional sweating state of the human body of the subject.
바람직하게는 상기 피검사자를 공간 상에서 누운 상태로 지지시키기 위한 인체 지지수단을 더 포함하며, 상기 인체 지지수단은, 광이 투과 가능한 투명 재질 베드, 매쉬형태의 그물망 베드 또는 복수개의 봉이 일정간격씩 평행하게 이격되어 위치된 평행봉 베드를 포함할 수 있다.Preferably, the apparatus further comprises a human body support means for supporting the examinee in a state of lying down on the space, wherein the human body support means includes a transparent material bed, a mesh-shaped mesh bed or a plurality of rods that allow light to pass through at a predetermined interval in parallel. It may include a parallel bar bed spaced apart.
여기서 상기 인체 지지수단은, 투명 유리 또는 투명 플라스틱으로 형성될 수 있다.The human body support means may be formed of transparent glass or transparent plastic.
이와 같은 본 발명에 의하면, 피검사자에 대한 광조사를 통해 피검사자의 발한반응에 따른 자율신경계의 이상 여부를 판단할 수 있는 발한진단기기를 제공할 수 있다.According to the present invention, it is possible to provide an antiperspirant diagnostic device that can determine whether the autonomic nervous system abnormality according to the perspiration response of the subject through light irradiation to the subject.
특히, 발색시약을 이용하지 않고 피검사자의 피부에 대한 광조사를 통해 발한반응에 대한 검사를 진행할 수 있어 피검사자의 피부 전체에 시약을 바름에 따라 피검사자가 거부감을 크게 느끼는 문제점을 해결하고 또한 검사 후 피검사자의 피부가 시약으로 더러워진 불결한 상태가 되는 문제점을 해결할 수 있다.In particular, it is possible to test for sweating response through light irradiation of the examinee's skin without using a coloring reagent, and solve the problem that the examinee feels a great sense of rejection by applying the reagent to the whole subject's skin. It is possible to solve the problem that the skin becomes dirty due to a reagent.
또한 피검사자의 피부에 광 조사를 하여 인체에서 분비되는 땀에 대한 광 반사를 기초로 발한반응을 검사함으로써, 발색 시약을 이용하는 경우에 피검사자의 발한 반응에 따라 분비되는 땀이 흘러 실제 땀이 발생하지 않은 부위의 발색시약까지도 반응되어 검사에 오류가 발생되는 문제를 해결할 수 있다.In addition, by irradiating the subject's skin with light to examine the sweating response based on the light reflection on the sweat secreted by the human body, when the color development reagent is used, the sweat secreted by the sweating reaction of the examinee does not cause actual sweating. Even the color development reagent of the site can be reacted to solve the problem of error in the test.
나아가서 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템을 통해서 피검사자의 인체에 대한 3차원적인 발한반응 검사가 가능해진다.Furthermore, through the diagnostic system using the human body sweat response according to the present invention it becomes possible to test the three-dimensional sweating response to the human body of the examinee.
또한 본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치에 의하면, 일상적인 환경과 같은 편안한 상태에서 피검사자를 빠르고 정확하게 진단할 수 있고, 발한의 특징 분석을 통한 진단과 인체모형 더미 위에 표시되는 디스플레이 방식을 통해 피검사자의 병소와 통증부위, 통증 정도를 알 수 있어 검사의 편의성과 효율성을 동시에 추구하는 것이 가능하다.In addition, according to the diagnostic apparatus using the human body perspiration reaction according to another aspect of the present invention, it is possible to quickly and accurately diagnose the subject in a comfortable state, such as the daily environment, the display through the diagnosis and character model dummy through the analysis of the characteristics of sweating Through the method, the lesion, pain area, and pain level of the examinee can be known, so that it is possible to simultaneously pursue convenience and efficiency of the test.
다만, 본 발명의 효과들은 이상에서 언급한 효과로 제한되지 않으며, 언급되지 않은 또 다른 효과들은 아래의 기재로부터 당업자에게 명확하게 이해될 수 있을 것이다.However, the effects of the present invention are not limited to the above-mentioned effects, and other effects not mentioned will be clearly understood by those skilled in the art from the following description.
도 1은 종래기술에 따른 발한진단기기(TST; Thermoregulatory Sweat Tester)의 구성도를 도시하며,1 is a block diagram of a sweat diagnosis device (TST; Thermoregulatory Sweat Tester) according to the prior art,
도 2는 본 발명의 일 양상에 따른 인체 발한 반응을 이용한 진단 시스템의 제1 실시예에 대한 구성도를 도시하며,2 is a block diagram of a first embodiment of a diagnostic system using a human body antiperspirant reaction according to an aspect of the present invention;
도 3은 본 발명의 일 양상에 따른 인체 발한 반응을 이용한 진단 시스템에서 광조사를 이용하여 발한반응을 측정하는 원리를 도시하며,Figure 3 shows the principle of measuring the sweating response using light irradiation in the diagnostic system using the human sweating response according to an aspect of the present invention,
도 4는 본 발명의 일 양상에 따른 인체 발한 반응을 이용한 진단 시스템에서 인체 지지수단의 실시예를 도시하며,Figure 4 shows an embodiment of a human body support means in a diagnostic system using a human body sweat response according to an aspect of the present invention,
도 5는 본 발명의 일 양상에 따른 인체 발한 반응을 이용한 진단 시스템의 제2 실시예에 대한 구성도를 도시하며,5 is a block diagram of a second embodiment of a diagnostic system using a human body antiperspirant reaction according to an aspect of the present invention;
도 6은 본 발명의 일 양상에 따른 인체 발한 반응을 이용한 진단 시스템에서 광 조사수단과 광 측정수단의 일실시예를 도시하며,6 illustrates an embodiment of a light irradiation means and a light measuring means in a diagnostic system using a human body sweat response according to an aspect of the present invention,
도 7은 본 발명의 일 양상에 따른 인체 발한 반응을 이용한 진단 시스템의 제3 실시예에 대한 구성도를 도시하며,7 is a block diagram of a third embodiment of a diagnostic system using a human sweating response according to an aspect of the present invention;
도 8은 본 발명의 일 양상에 따른 인체 발한 반응을 이용한 진단 시스템의 제4 실시예 및 제5 실시예에 대한 구성도를 도시한다.8 is a block diagram of a fourth embodiment and a fifth embodiment of a diagnostic system using a human body antiperspirant reaction according to an aspect of the present invention.
도 9는 본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치의 구조 설명하는 도면이고,9 is a view for explaining the structure of a diagnostic apparatus using a human body sweat response according to another aspect of the present invention,
도 10은 본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치의 구성요소간의 연결을 설명하는 도면이고,10 is a view for explaining the connection between the components of the diagnostic apparatus using the human body perspiration reaction according to another aspect of the present invention,
도 11은 본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치의 제어부에 대한 기능을 설명하는 도면이고,11 is a view for explaining the function of the control unit of the diagnostic device using the human body sweat response according to another aspect of the present invention,
도 12는 본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치의 작동 과정을 나타낸 플로우차트이고,12 is a flowchart illustrating an operation process of a diagnostic apparatus using a human body sweat response according to another aspect of the present invention.
도 13은 본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치의 카메라 등의 광학계와 구동장치를 설명하는 도면이고,FIG. 13 is a view illustrating an optical system and a driving device such as a camera of a diagnostic device using a human body antiperspirant reaction according to another aspect of the present invention.
도 14는 본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치의 디스플레이부에서 표시되는 예를 설명하는 도면이고,14 is a view for explaining an example displayed on the display unit of the diagnostic device using the body perspiration reaction according to another aspect of the present invention,
도 15는 종래의 TST 방식의 발한 영상과 패턴 진단의 일예를 도시한 도면이다.15 is a diagram illustrating an example of a sweating image and pattern diagnosis of a conventional TST method.
본 발명에 따른 인체 발한 반응을 이용한 진단 시스템은, 열 조절에 의한 피검사자의 발한반응을 검사하기 위한 시스템으로서, 피검사자의 체온을 상승시켜 발한 반응을 유도하기 위한 온도조절수단; 상기 피검사자의 피부로 광을 조사하는 광 조사수단; 상기 피검사자의 피부로부터 반사 광을 수집하는 광 측정수단; 및 상기 광 측정수단에서 수집한 반사 광의 광량 변화 또는 광강도 분포를 기초로 상기 피검사자의 발한 반응을 측정하는 인체 진단수단을 포함할 수 있다.Diagnosis system using the human perspiration reaction according to the present invention, a system for examining the perspiration response of the subject by heat control, temperature control means for inducing a perspiration reaction by raising the body temperature of the subject; Light irradiation means for irradiating light to the skin of the examinee; Light measuring means for collecting the reflected light from the skin of the examinee; And it may include a human diagnostic means for measuring the perspiration response of the subject based on the change in the amount of light or the intensity distribution of the reflected light collected by the light measuring means.
본 발명과 본 발명의 동작상의 이점 및 본 발명의 실시에 의하여 달성되는 목적을 설명하기 위하여 이하에서는 본 발명의 바람직한 실시예를 예시하고 이를 참조하여 살펴본다.In order to explain the present invention, the operational advantages of the present invention, and the objects achieved by the practice of the present invention, the following describes exemplary embodiments of the present invention and looks at it with reference.
먼저, 본 출원에서 사용한 용어는 단지 특정한 실시예를 설명하기 위해 사용된 것으로서, 본 발명을 한정하려는 의도가 아니며, 단수의 표현은 문맥상 명백하게 다르게 뜻하지 않는 한, 복수의 표현을 포함할 수 있다. 또한 본 출원에서, "포함하다" 또는 "가지다" 등의 용어는 명세서 상에 기재된 특징, 숫자, 단계, 동작, 구성요소, 부품 또는 이들을 조합한 것이 존재함을 지정하려는 것이지, 하나 또는 그 이상의 다른 특징들이나 숫자, 단계, 동작, 구성요소, 부품 또는 이들을 조합한 것들의 존재 또는 부가 가능성을 미리 배제하지 않는 것으로 이해되어야 한다.First, the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention, and singular forms may include plural forms unless the context clearly indicates otherwise. Also in this application, terms such as "comprise" or "have" are intended to indicate that there is a feature, number, step, action, component, part, or combination thereof described on the specification, one or more other It is to be understood that the present invention does not exclude the possibility of adding or presenting features or numbers, steps, operations, components, components, or combinations thereof.
본 발명을 설명함에 있어서, 관련된 공지 구성 또는 기능에 대한 구체적인 설명이 본 발명의 요지를 흐릴 수 있다고 판단되는 경우에는 그 상세한 설명은 생략한다.In describing the present invention, when it is determined that the detailed description of the related well-known configuration or function may obscure the gist of the present invention, the detailed description thereof will be omitted.
본 발명의 일 양상에 따르면, 발색시약을 사용하지 않고 피검사자에 광 조사를 수행하여 반사 광에 따른 피검사자의 발한반응을 검사하는 방안을 개시한다.According to an aspect of the present invention, there is disclosed a method for inspecting the sweating response of the subject according to the reflected light by performing light irradiation on the subject without using a color reagent.
도 2는 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템의 제1 실시예에 대한 구성도를 도시한다.Figure 2 shows a block diagram of a first embodiment of a diagnostic system using a human perspiration reaction according to the present invention.
본 발명에 따른 인체 발한 반응을 이용한 진단 시스템은, 발한반응 검사수단(200), 온도조절수단(300), 인체 감시수단(400), 인체 지지수단(500), 인체 진단수단(미도시) 등을 포함하여 구성될 수 있다.Diagnosis system using the human body perspiration reaction according to the present invention, perspiration reaction means 200, temperature control means 300, human body monitoring means 400, human body support means 500, human diagnostic means (not shown), etc. It may be configured to include.
본 발명의 주된 특징적 구성인 발한반응 검사수단(200)은 광 조사수단(210)과 광 측정수단(230)을 포함하여 구성될 수 있는데, 광 조사수단(210)은 피검사자(10)의 피부로 광(211)을 조사하며, 광 측정수단(230)은 피검사자(10)의 피부로 조사되어 피부에서 반사되는 반사 광(231)을 수집한다. 그리고 수집된 반사 광(231)을 기초로 인체 진단수단(미도시)이 피검사자(10)의 발한반응을 측정할 수 있다. 여기서 인체 진단수단은 반사 광(231)에서 수집된 반사 광의 특성에 따라 피검사자(10)의 땀 분비 여부를 분석하기 위한 PC 등의 장치를 포함하여 구성될 수 있다.The main characteristic sweat perspiration test means 200 of the present invention may include a light irradiation means 210 and a light measuring means 230, the light irradiation means 210 to the skin of the examinee 10 The light 211 is irradiated, and the light measuring means 230 collects the reflected light 231 which is irradiated onto the skin of the examinee 10 and reflected from the skin. The human diagnosis means (not shown) may measure the sweating response of the examinee 10 based on the collected reflected light 231. Here, the human diagnostic means may include a device such as a PC for analyzing the sweat glands of the examinee 10 according to the characteristics of the reflected light collected by the reflected light 231.
본 발명에서는 땀이 분비되지 않은 피부에 대한 광의 반사 특성과 땀이 분비된 피부에서 땀에 대한 광의 반사 특성이 상이한 점을 이용하여 발한반응을 측정하는데, 즉 땀이 분비되지 않은 피부로 조사되어 반사되는 반사 광의 경우와 땀이 분비된 피부로 조사되어 반사되는 반사 광의 경우에 광의 간섭, 굴절, 산란, 흡수, 반사 등의 특성으로 광량, 광강도 등에서 상이한 차이가 발생되므로 이를 기초로 피검사자의 발한반응을 검사하게 된다.In the present invention, the perspiration response is measured by using the difference between the light reflection characteristics of the sweat and non- sweaty skin and the light reflection characteristics of the sweat in the sweaty skin, that is, the irradiated skin is not irradiated and reflected. In the case of the reflected light and the reflected light irradiated to the sweaty skin and reflected, the difference in light quantity, light intensity, etc. is generated due to the characteristics of interference, refraction, scattering, absorption, reflection, etc. Will be examined.
본 발명에서는 피검사자에 대한 조사 광으로서 가시광, 적외선광, 자외선광 중 어느 하나를 선택적으로 이용할 수 있으며, 이를 위해 광 조사수단(210)은 가시광을 발생시켜 피검사자(10)의 피부로 조사하는 가시광 광원부, 적외선광을 발생시켜 피검사자(10)의 피부로 조사하는 적외선광 광원부 또는 자외선광을 발생시켜 피검사자(10)의 피부로 조사하는 자외선광 광원부를 포함할 수 있고, 또한 광 측정수단(230)은 광 조사수단(210)의 광 종류에 따라 가시광에 대한 광센서나 카메라, 또는 적외선광에 대한 IR 광센서나 IR 카메라, 또는 자외선광에 대한 UV 광센서나 UV 카메라를 구비하는 수광부를 포함할 수 있다. In the present invention, any one of visible light, infrared light, and ultraviolet light may be selectively used as irradiated light to the examinee, and for this, the light irradiating means 210 generates visible light and irradiates the skin of the examinee 10 to the light. , An infrared light source unit generating infrared light to irradiate the skin of the test subject 10 or an ultraviolet light source unit generating ultraviolet light and irradiating the skin of the test subject 10, and the light measuring means 230 Depending on the type of light of the light irradiation means 210 may include a light sensor or camera for visible light, or an IR light sensor or IR camera for infrared light, or a light receiving unit having a UV light sensor or UV camera for ultraviolet light. have.
각각의 광 특성에 따른 발한반응 검사 원리를 도 3에 도시된 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템에서 광 조사를 이용하여 발한반응을 측정하는 원리를 참조하여 살펴보기로 한다.The principle of perspiration test according to each optical characteristic will be described with reference to the principle of measuring perspiration using light irradiation in the diagnostic system using the human perspiration reaction shown in FIG. 3.
가시광, 적외선광, 자외선광 등이 일정 광량이나 광강도(A1)로 땀이 분비되지 않은 피검사자의 피부로 조사되면 광 종류에 따라 반사광의 광량이나 광강도의 정도가 조금 상이하게 나타날 수는 있으나 상기 도 3의 (a)와 같이 반사 광은 일정하게 균일한 광량이나 광강도(A2)로 수집되게 된다.When visible light, infrared light, ultraviolet light, etc. are irradiated to the skin of a subject who is not secreted with a certain amount of light or light intensity (A1), the amount of reflected light or the intensity of light may vary slightly depending on the type of light. As shown in FIG. 3A, the reflected light is collected at a uniform amount of light or light intensity A2.
그러나 땀이 분비된 피검사자의 피부로 광이 조사되면 땀에 대한 광의 간섭, 굴절, 흡수, 반사 등의 특성으로 인해 반사 광의 광량이나 광강도는 변화되어 수집되는데, 가령 상기 도 3의 (b)에서 가시광을 일정 광량이나 광강도(A1)로 땀이 분비된 피검사자의 피부로 조사하는 경우에 땀에 의해 반사되는 반사광은 땀이 분비되지 않은 피부에 대한 반사광보다 더 많은 광량이나 광강도(A3)로 수집될 수 있다.However, when light is irradiated onto the skin of a sweat-tested subject, the amount of light or the intensity of the reflected light is changed and collected due to characteristics such as interference of light, refraction, absorption, and reflection on sweat, for example, in FIG. When visible light is irradiated to the skin of a subject whose sweat is secreted at a constant amount of light or light intensity (A1), the reflected light reflected by the sweat is more light or intensity (A3) than the reflected light to the non-sweated skin. Can be collected.
또한 상기 도 3의 (c)에서 적외선광을 일정 광량이나 광강도(A1)로 땀이 분비된 피검사자의 피부로 조사하는 경우에 적외선광이 땀에 흡수되는 특성으로 인해 반사광은 땀이 분비되지 않은 피부에 대한 반사광보다 더 적은 광량이나 광강도(A4)로 수집될 수 있다.In addition, when the infrared light is irradiated to the skin of a subject whose sweat is secreted at a predetermined light intensity or light intensity (A1) in FIG. 3 (c), the reflected light is not secreted due to the characteristic that the infrared light is absorbed by the sweat. It can be collected with less light or light intensity A4 than reflected light to the skin.
나아가서 상기 도 3의 (d)에서 자외선광을 일정 광량이나 광강도(A1)로 땀이 분비된 피검사자의 피부로 조사하는 경우에 자외선광이 땀이 분비되지 않은 피부와 대비하여 땀에 의해 반사가 더 잘 일어나게 되어 땀이 분비되지 않은 피부에 대한 반사광보다 더 많은 광량이나 광강도(A5)로 수집될 수 있으며, 간섭이 일어나게 되어 땀이 분비되지 않은 피부에 대한 반사광보다 더 많으면서 불규칙한 광량이나 광강도(A5)로 수집될 수 있다.Furthermore, when the ultraviolet light is irradiated to the skin of a subject whose sweat is secreted at a predetermined light intensity or light intensity (A1) in FIG. 3 (d), the ultraviolet light is reflected by sweat in contrast to the skin where the sweat is not secreted. It is more likely to occur and can be collected with more light or intensity (A5) than reflected light for non-sweatened skin, and interference can occur, resulting in more irregular light or light than reflected light for non-sweated skin. Can be collected at an intensity A5.
본 발명에서는 이와 같이 땀이 분비되지 않은 피부에 대한 광 특성과 땀에 대한 광 특성이 상이한 점을 이용하여 피검사자의 발한반응에 대한 측정을 하게 된다.In the present invention, the measurement of the sweating response of the subject by using the point that the optical properties of the sweat and the light properties for the non-secreted skin is different.
나아가서 광 조사수단(210)은 가시광, 적외선광, 자외선광 중 둘 이상의 서로 다른 종류의 광으로 피검사자(10)를 조사하고, 광 측정수단(230)은 반사된 둘 이상의 서로 다른 종류의 반사 광을 수집하며, 인체 진단수단이 수집된 둘 이상의 서로 다른 종류의 반사 광을 기초로 발한반응을 측정하되 그 결과를 종합하여 보상된 결과로 발한반응을 측정할 수도 있다.Furthermore, the light irradiation means 210 irradiates the examinee 10 with at least two different types of light among visible light, infrared light, and ultraviolet light, and the light measuring means 230 emits two or more different kinds of reflected light reflected. In addition, by measuring the perspiration response based on two or more different types of reflected light collected by the human diagnostic means, the results may be combined to measure the perspiration response.
다시 도 2로 회귀하여 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템의 제1 실시예에 대한 구성에 대하여 계속 살펴보기로 한다.Returning to FIG. 2 again, the configuration of the first embodiment of the diagnostic system using the human body antiperspirant reaction according to the present invention will be described.
온도조절수단(300)은 피검사자(10)의 체온을 상승시켜 발한반응을 유도하는데, 이를 위해서 온도조절수단(300)은 열선 등을 구비하여 피검사자(10)가 위치된 공간 상의 온도를 높임으로써 피검사자(10)의 체온을 상승시킬 수 있다.The temperature control means 300 raises the body temperature of the subject 10 to induce a sweating reaction. For this purpose, the temperature adjusting means 300 is provided with a heating wire to increase the temperature in the space where the subject 10 is located. The body temperature of (10) can be raised.
그리고 인체 감시수단(400)은 피검사자(10)의 신체 상태를 실시간 센싱하기 위해 선택적으로 체온감지기, 심박측정기, 혈압측정기 등의 여러 센서를 구비할 수 있으며, 인체 감지수단(400)에서 센싱되는 피검사자(10)의 신체 상태 정보는 온도조절수단(300)에서 피검사자(10)의 체온 상승 정도를 조절하기 위한 기초 정보로 활용될 수도 있고, 더 나아가서 특정 피검사자에 대한 과거 검사 기록을 기초로 피검사자(10)의 신체 상태를 확인하거나 온도 조절을 위한 정보로서 제공될 수도 있다.In addition, the human body monitoring means 400 may optionally include various sensors such as a body temperature sensor, a heart rate monitor, a blood pressure monitor, and the like to be sensed by the human body detecting means 400. The physical state information of 10 may be used as basic information for controlling the degree of increase in body temperature of the examinee 10 in the temperature control means 300, or further, based on the past test record for the specific examinee 10 It may be provided as information for checking the physical condition of the) or temperature control.
인체 지지수단(500)은 피검사자(10)가 공간 상에서 누운 상태로 지지시키는데, 여기서 인체 지지수단(500)은 피검사자(10)를 지지할 수 있는 안정적인 다양한 종류의 재질로 형성될 수도 있지만, 조사되는 광이 투과할 수 있는 재질로 형성되는 것이 보다 바람직하다. The human body support means 500 supports the examinee 10 in a lying state on the space, where the human body support means 500 may be formed of various kinds of stable materials capable of supporting the examinee 10, It is more preferable that it is formed of a material which can transmit light.
가령 상기 도 2의 제1 실시예와 같이 피검사자(10)가 정면을 향하여 바르게 누운 상태에서 피검사자(10)의 상면만을 광 조사하여 발한반응을 검사한 후 피검사자(10)가 뒤돌아 누운 상태에서 피검사자(10)의 후면만을 광 조사하여 발한반응을 검사하는, 두번의 검사 과정으로서 피검사자(10)의 전체에 대한 발한반응 검사를 수행할 수도 있지만, 보다 바람직하게는 이후에 제시되는 실시예를 통해 살펴보겠지만 피검사자(10)가 정면을 향하여 바르게 누운 상태에서 한번에 피검사자(10)의 상면과 하면 모두를 광 조사하여 발한반응을 검사하는 것이 효과적이므로 이를 위해서 인체 지지수단(500)은 광이 투과 가능한 재질로 형성되는 것이 바람직하다. For example, as shown in the first embodiment of FIG. 2, the examinee 10 is lightly lying down toward the front to examine the sweating reaction by only irradiating the upper surface of the examinee 10, and then examines the examinee ( Although it is possible to perform the perspiration test on the entire subject 10 as a two-time inspection process by examining only the rear surface of the light 10 to examine the perspiration reaction, it is more preferable to look through the following examples. Although it is effective to examine the sweating reaction by irradiating both the upper and lower surfaces of the examinee 10 at a time in the state in which the examinee 10 is correctly laid toward the front, the human body support means 500 is made of a material that can transmit light. It is preferably formed.
이를 위해서 인체 지지수단(500)은 투명한 유리나 플라스틱 등의 재질로 형성될 수도 있고 나아가서 가능한 피검사자(10)의 피부에 대한 광 조사가 방해되지 않는 구조로 형성될 수 있는데, 이와 관련하여 도 4는 본 발명에 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템에서 인체 지지수단의 실시예를 도시한다.To this end, the human body support means 500 may be formed of a material such as transparent glass or plastic, and furthermore, may be formed in a structure in which light irradiation to the skin of the examinee 10 is not hindered. An embodiment of a human body supporting means in a diagnostic system using the human body antiperspirant reaction according to the present invention is shown.
상기 도 4의 (a)에서는 인체 지지수단이 광이 투과 가능한 투명 재질 베드(500a)로서, 유리나 투명 플라스틱 등으로 베드를 형성한 경우를 도시하며, 상기 도 4의 (b)에서는 피검사자의 피부에 대한 광 조사가 최대한 방해되지 않도록 프레임(550b) 상에 메쉬형태의 그물망(510b)으로 베드(500b)를 형성한 경우를 도시한다. 또한 상기 도 4의 (c)에서도 피검사자의 피부에 대한 광 조사가 최대한 방해되지 않도록 프레임(550c) 상에 복수개의 봉(510c)이 일정간격씩 평행하게 이격시켜 베드(500c)를 형성한 경우를 도시한다. 나아가서 인체 지지수단의 광 투과율을 더욱 높이기 위해서 상기 도 4의 (b)에 도시된 그물망(510b)과 상기 도 4의 (c)에 도시된 봉(510c)은 투명 재질의 유리나 플라스틱 등으로 형성될 수도 있다.FIG. 4A illustrates a case where the human body support means is a transparent material bed 500a through which light is transmitted, and a bed is formed of glass, transparent plastic, or the like. In FIG. The case where the bed 500b is formed of a mesh 510b in the form of a mesh on the frame 550b so as not to disturb the light irradiation as much as possible is shown. In addition, in FIG. 4C, a plurality of rods 510c are spaced apart at a predetermined interval in parallel to form a bed 500c on the frame 550c so that light irradiation to the skin of the examinee is not disturbed as much as possible. Illustrated. Furthermore, in order to further increase the light transmittance of the human body support means, the mesh 510b shown in FIG. 4B and the rod 510c shown in FIG. 4C may be formed of transparent glass or plastic. It may be.
이와 같이 본 발명에서 인체 지지수단을 광이 투가 가능하도록 형성시킴으로써 피검사자의 상면과 하면 모두를 한번에 광 조사할 수 있는데, 이에 대한 하나의 실시예로서 도 5는 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템의 제2 실시예에 대한 구성도를 도시한다.In this way, by forming the human body support means to allow light transmission in the present invention, both the upper and lower surfaces of the examinee can be irradiated with light at one time. As one embodiment thereof, FIG. 5 uses the antiperspirant reaction according to the present invention. A schematic diagram of a second embodiment of a diagnostic system is shown.
상기 도 5에 도시된 제2 실시예에서는 한번에 피검사자(10)의 상면과 하면 모두를 광 조사하여 피검사자(10)의 인체 전체에 대한 발한반응을 검사할 수 있는데, 이를 위해 피검사자(10)를 공간 상에 지지시키는 인체 지지수단(500b)으로 상기 도 4의 (b)에 도시된 메쉬형태의 그물망 베드를 적용하였다.In the second exemplary embodiment shown in FIG. 5, the upper and lower surfaces of the examinee 10 may be irradiated at once to inspect the sweating response to the entire human body of the examinee 10. As a human body support means (500b) to support the image is applied to the mesh bed of the mesh type shown in Figure 4 (b).
그리고 피검사자(10)의 상면에 대한 발한반응 검사를 위해서 피검사자(10)의 상면 상부에 발한반응 검사수단(200b1, 200b2)을 배치하고, 피검사자(10)의 하면 하부에도 발한반응 검사수단(200c1, 200c2)을 배치하였다. In addition, perspiration test means 200b1 and 200b2 are disposed on the upper surface of the examinee 10 to check the sweating response to the upper surface of the examinee 10, and sweat perspiration test means 200c1 and below the lower surface of the examinee 10, respectively. 200c2) was placed.
그리고 상기 도 2의 제1 실시예에서는 발한반응 검사수단(200)의 광 조사수단(210)과 광 측정수단(230)이 개별적으로 분리되어 구성되었지만, 상기 도 5의 제2 실시예에서 발한반응 검사수단(200b1, 200b2, 200c1, 200c2)은 광 조사수단과 광 측정수단을 하나의 하우징 상에 일체형으로 형성시켰는데, 도 6에 도시된 본 발명에 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템에서 광 조사수단과 광 측정수단의 일실시예와 같이 발한반응 검사수단(200a)으로서 하나의 하우징(240a)에 광 조사수단(210a)과 광 측정수단(230a)이 일체형으로 구성된 형태를 적용함으로써 보다 좁은 공간 상에 광 조사수단과 광 측정수단의 배치가 가능하고, 또한 광 조사 수단의 광 조사에 따른 광 측정 수단의 반사 광에 대한 수광 각도 조절이 별도로 이루어질 필요가 없게 된다.In addition, in the first embodiment of FIG. 2, the light irradiation unit 210 and the light measuring unit 230 of the sweating test means 200 are separately configured, but the sweating reaction in the second embodiment of FIG. 5. The inspection means (200b1, 200b2, 200c1, 200c2) is formed integrally on the light irradiation means and the light measuring means on one housing, the diagnostic system using the human body sweat response according to the present invention shown in Figure 6 As in one embodiment of the light irradiation means and the light measuring means by applying the form of the light irradiation means 210a and the light measuring means 230a integrally in one housing 240a as a sweat perspiration test means (200a) The light irradiation means and the light measuring means can be arranged in a narrower space, and the light receiving angle of the reflected light of the light measuring means according to the light irradiation of the light irradiation means does not need to be separately made.
나아가서 상기 도 5의 제2 실시예에서는 보다 정밀도 높은 발한반응 검사를 위해서 피검사자(10)의 인체를 구역으로 나누어 구획하고 각 구역마다 광을 조사하여 반사광을 수집하도록 구역별 복수개의 발한반응 검사수단(200b1, 200b2, 200c1, 200c2)을 배치하였다. Furthermore, in the second embodiment of FIG. 5, a plurality of perspiration reaction inspection means for each zone is configured to divide the human body of the examinee 10 into zones and to collect reflected light by irradiating light in each zone for more accurate perspiration reaction inspection ( 200b1, 200b2, 200c1, 200c2) were disposed.
한걸음 더 나아가서 앞서 살펴본 바와 발한반응 검사수단(200b1, 200b2, 200c1, 200c2)이 피검사자(10)의 동일한 피부 부위에 대하여 서로 다른 종류의 광을 조사하고 이에 대한 반사광을 수집하도록 복수개 배치하여 보다 검사의 정확도를 높일 수도 있다. Furthermore, as described above, the anti-perspirant test means 200b1, 200b2, 200c1, and 200c2 radiate different types of light to the same skin part of the examinee 10 and collect a plurality of reflected light to collect the reflected light. You can also increase the accuracy.
또한 피검사자(10)의 상면과 하면 각각에 대한 발한반응을 유도하기 위해서 피검사자(10)의 상면에 대한 발한반응을 유도하는 온도조절수단(300a)과 피검사자(10)의 하면에 대한 발한반응을 유도하는 온도조절수단(300b)을 개별적으로 배치하였다.In addition, in order to induce a sweating response to the upper and lower surfaces of the subject 10, the temperature control means (300a) to induce a sweating response to the upper surface of the subject 10 induces an sweating response to the lower surface of the examinee (10) Temperature control means (300b) to be arranged separately.
이와 같이 본 발명에 따른 상기 제2 실시예를 통해서 피검사자(10)의 상면에 대한 발한반응 검사 수행과 하면에 대한 발한반응 검사 수행을 분리하여 실시하지 않고 한번에 피검사자(10)의 인체 전체에 대한 발한반응 검사를 수행할 수 있게 된다.As described above, according to the second embodiment of the present invention, the sweat test on the upper surface of the test subject 10 and the sweat test on the lower surface of the test subject 10 are not performed separately. The reaction test can be performed.
나아가서 상기 도 6의 제2 실시예에서는 피검사자(10)의 상면과 하면에 대한 발한반응 검사에 한번에 수행하기 위해서 발한반응 검사수단(200b1, 200b2, 200c1, 200c2)을 피검사자(10)의 상면과 하면 각각에 복수개 배치하였으나, 발한반응 검사수단의 설치 개수를 최소화시키면서 피검사자에 인체 전체에 대한 발한반응 검사가 가능한데 이와 관련하여 도 7은 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템의 제3 실시예에 대한 구성도를 도시한다.Furthermore, in the second embodiment of FIG. 6, the antiperspirant test means 200b1, 200b2, 200c1, and 200c2 are performed on the upper and lower surfaces of the examinee 10 to perform the perspiration test on the upper and lower surfaces of the examinee 10 at one time. Although a plurality of arrangements are provided in each of them, the test can be performed on the entire human body while minimizing the number of installations of the antiperspirant test means. In this regard, FIG. 7 illustrates a third embodiment of a diagnosis system using the antiperspirant reaction according to the present invention. The schematic diagram is shown.
상기 도 7의 제3 실시예에서는 광 조사수단과 광 측정수단을 포함하는 발한반응 검사수단(200d, 200e)을 수평 방향으로 이송시키는 이송수단을 형성시켰는데, 이송수단은 피검사자(10)의 인체와 평행하게 수평방향으로 형성된 수평 이송레일(250d, 250e)과 발한반응 검사수단(200d, 200e)을 수평 이송레일(250d, 250e) 상에서 이동시키기 위한 이송모터(미도시)를 포함하여, 발한반응 검사수단(200d, 200e)이 수평방향으로 피검사자(10)의 인체를 따라 광을 조사하고, 이에 대응하여 반사 광을 수집할 수 있다.In the third embodiment of FIG. 7, a transfer means for transferring the sweating test means 200d and 200e including light irradiation means and light measuring means in a horizontal direction is formed, and the transfer means is a human body of the examinee 10. Perspiration reaction, including a transfer motor (not shown) for moving the horizontal transfer rails 250d and 250e and the anti-perspiration reaction means 200d and 200e formed in the horizontal direction in parallel to the horizontal transfer rails 250d and 250e. The inspection means 200d and 200e may irradiate light along the human body of the examinee 10 in the horizontal direction and collect the reflected light correspondingly.
한걸음 더 나아가서 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템은 피검사자의 인체의 상면, 하면 및 측면에 대하여 광을 조사하여 3차원적으로 발한반응을 검사할 수도 있는데, 이를 위해서 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템은 상기 도 7의 제3 실시예에 도시된 수평방향의 이송수단뿐만 아니라 수직방향의 이송수단을 더 포함할 수 있다.Furthermore, the diagnostic system using the human body sweating reaction according to the present invention may examine the sweating reaction in three dimensions by irradiating light on the upper, lower, and side surfaces of the subject's human body. The diagnostic system using the reaction may further include a vertical conveying means as well as a horizontal conveying means shown in the third embodiment of FIG.
가령, 도 8의 (a)에 도시된 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템의 제4 실시예에 대한 구성도와 같이 광 조사수단과 광 측정수단을 포함하는 발한반응 검사수단(200f, 200g)을 피검사자(10)의 측면에서 수직 방향으로 이송시키기 위한 수직방향 이송수단이 구비될 수 있으며, 수직방향 이송수단은 피검사자(10)의 인체와 수직방향으로 형성된 수직 이송레일(250f, 250g)과 발한반응 검사수단(200f, 200g)을 수직 이송레일(250f, 250g) 상에서 이동시키기 위한 이송모터(미도시)를 포함하여, 발한반응 검사수단(200f, 200g)이 수직방향으로 피검사자(10)의 인체를 따라 광을 조사하고, 이에 대응하여 반사 광을 수집할 수 있다.For example, as shown in the configuration of the fourth embodiment of the diagnostic system using the human body antiperspirant reaction according to the present invention shown in Figure 8 (a) sweat perspiration test means 200f, 200g including light irradiation means and light measuring means ) May be provided with a vertical conveying means for conveying in the vertical direction from the side of the subject 10, the vertical conveying means is a vertical conveying rail (250f, 250g) formed in a vertical direction with the human body of the subject 10 Including a transfer motor (not shown) for moving the sweating test means (200f, 200g) on the vertical transfer rails (250f, 250g), the sweating test means (200f, 200g) of the subject 10 in the vertical direction The light may be irradiated along the human body, and the reflected light may be collected correspondingly.
또한 발한반응 검사수단이 피검사자의 인체와 일정한 이격거리를 유지하면서 광 조사를 함으로써 보다 정확하게 피검사자의 발한반응 검사가 가능할 수 있는데, 상기 도 8의 (b)에 도시된 본 발명에 따른 인체 발한 반응을 이용한 진단 시스템의 제5 실시예에 대한 구성도와 같이 광 조사수단과 광 측정수단을 포함하는 발한반응 검사수단(200h1, 200h2)을 피검사자(10)의 인체를 중심으로 회전시켜서 광을 조사하고 반사 광을 수집함으로써 발한반응 검사수단(200h1, 200h2)이 피검사자(10)와 항상 동일한 이격 거리를 두고 광의 조사와 이에 대한 반사 광의 수집이 가능하다.In addition, the perspiration test means may be able to more accurately test the perspiration test of the subject by maintaining a constant distance from the human body of the subject, the perspiration reaction according to the present invention shown in Figure 8 (b) As shown in the configuration of the fifth embodiment of the diagnostic system used, the antiperspiration reaction means 200h1 and 200h2 including light irradiation means and light measuring means are rotated about the human body of the examinee 10 to irradiate light and reflect light. By collecting the perspiration test means (200h1, 200h2) is always at the same separation distance with the examinee 10 can be irradiated with light and collect the reflected light thereto.
이를 위해서 상기 도 8의 (b)와 같이 피검사자(10)의 인체를 중심으로 동일한 이격거리로 형성된 원형 이송레일(250h)과 이송레일(250h) 상에서 발한반응 검사수단(200h1, 200h2)을 이송시키기 위한 이송모터(미도시)를 포함하여 회전수단을 형성시킬 수 있다.To this end, as shown in (b) of FIG. 8, the sweat transfer test means 200h1 and 200h2 are transported on the circular transfer rail 250h and the transfer rail 250h formed at the same separation distance around the human body of the examinee 10. Including a transfer motor (not shown) for forming a rotation means.
이상에서 살펴본 바와 같은 본 발명의 일 양상에 따르면, 피검사자에 대한 광조사를 통해 피검사자의 발한반응에 따른 자율신경계의 이상 여부를 판단할 수 있는 발한진단기기를 제공할 수 있는데, 특히 발색시약을 이용하지 않고 피검사자의 피부에 대한 광조사를 통해 발한반응에 대한 검사를 진행할 수 있어 피검사자의 피부 전체에 시약을 바름에 따라 피검사자가 거부감을 크게 느끼는 문제점을 해결하고 또한 검사 후 피검사자의 피부가 시약으로 더러워진 불결한 상태가 되는 문제점을 해결할 수 있다.According to an aspect of the present invention as described above, it is possible to provide an antiperspirant diagnostic device that can determine the abnormality of the autonomic nervous system according to the perspiration response of the examinee through light irradiation to the examinee, in particular using a color reagent It is possible to test for sweating reaction through light irradiation of the examinee's skin, which solves the problem that the examinee feels great rejection as the reagent is applied to the whole skin of the examinee and the subject's skin becomes dirty after the test. The problem of becoming unclean can be solved.
또한 본 발명의 일 양상에 따르면, 피검사자의 피부에 광 조사를 하여 인체에서 분비되는 땀에 대한 광 반사를 기초로 발한반응을 검사함으로써, 발색 시약을 이용하는 경우에 피검사자의 발한 반응에 따라 분비되는 땀이 흘러 실제 땀이 발생하지 않은 부위의 발색시약까지도 반응되어 검사에 오류가 발생되는 문제를 해결할 수 있다.In addition, according to an aspect of the present invention, by irradiating the skin of the examinee to examine the sweat perspiration based on the light reflection on the sweat secreted by the human body, when using a coloring reagent sweat secreted according to the sweat perspiration of the subject As a result, even the coloring reagent in the area where the actual sweat did not react can solve the problem of error in the test.
다음으로 본 발명의 다른 양상에 따르면, 일상적인 환경과 같은 편안한 상태에서 피검사자의 진단을 빠르고 정확하게 수행할 수 있으며, 발한의 특징 분석을 통한 진단과 인체모형 더미 위에 표시되는 디스플레이 방식을 통해 피검사자의 병소와 통증부위, 통증 정도를 자세히 알 수 있어 검사의 편의성과 효율성을 동시에 추구할 수 있는 방안을 개시한다.Next, according to another aspect of the present invention, the diagnosis of the subject can be performed quickly and accurately in a comfortable state such as a daily environment, and the subject's lesion through the display method displayed on the dummy and the dummy by analyzing the characteristics of sweating. The present invention provides a method for pursuing convenience and efficiency at the same time by providing detailed information on pain, pain area, and pain level.
도 9는 본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치의 구조 설명하는 도면으로서 (a)는 정면도이고, (b)는 측면도이며, 도 10은 인체 발한 반응을 이용한 진단 장치의 구성요소간의 연결을 설명하는 도면이다. 인체 발한 반응을 이용한 진단 장치는 챔버(40), 온도조절수단(300), 발한반응 검사수단(200), 인체 감시수단(400), 챔버 내부 상태 센서부(600), 챔버 내부 상태 조절부(610), 소프트웨어(700), 디스플레이부(800) 및 제어부(900) 등을 포함하여 구성될 수 있다.9 is a view for explaining the structure of the diagnostic device using the human body sweating according to another aspect of the present invention (a) is a front view, (b) is a side view, Figure 10 is a component of the diagnostic device using the human sweating response It is a figure explaining the connection between. Diagnosis apparatus using the human body perspiration reaction chamber 40, temperature control means 300, perspiration reaction test means 200, human body monitoring means 400, chamber internal state sensor 600, chamber internal state control unit ( 610, the software 700, the display 800, the controller 900, and the like.
챔버(40)는 피검사자의 출입이 용이하도록 챔버(40)의 상단에 형성된 고리(41)에 회동가능하게 결착된 투명창(42)과 투명창(42)을 챔버의 하단에 체결하는 체결부(43)를 포함할 수 있고, 챔버(40)를 지지하는 챔버 지지대(30)를 더 포함할 수 있다. 이러한 챔버(캡슐 또는 상자)는 고리부와 체결부로 구성되어 피검사자의 출입이 용이하게 구성되며 안전성을 확보할 수 있는 구조로 제조되는 것이 바람직하다. 또한 종래의 미닫이 구조로 하여도 무방하다. 또한 챔버는 내부에 카메라, 조명, 광학계 및 구동부 등을 구비할 수 있으며, 투명창(42) 뿐만 아니라 챔버 전체를 투명창 또는 반투명창으로 구성하여 진단자가 진단기기 내부의 상태를 육안으로 확인하는 것을 가능하도록 할 수 있다. 또한 챔버는 전체가 단열 구조로 이루어질 수 있다.The chamber 40 is a fastening part for fastening the transparent window 42 and the transparent window 42 which are rotatably attached to the ring 41 formed at the top of the chamber 40 so that the examinee can easily enter and exit the chamber 40. 43), and may further include a chamber support (30) for supporting the chamber (40). Such a chamber (capsule or box) is composed of a hook portion and a fastening portion is preferably configured to be easily constructed and to ensure the safety of the examinee entrance and exit. Moreover, it is good also as a conventional sliding structure. In addition, the chamber may include a camera, lighting, an optical system, a driving unit, and the like, and the diagnoser visually checks the state of the diagnosis apparatus by configuring the entire chamber as a transparent window or a translucent window as well as the transparent window 42. You can make it possible. In addition, the chamber may be made of a whole heat insulating structure.
도 9에 도시되지는 않았지만, 도 2에 도시된 바와 같이 챔버(40) 내부에는 인체 지지수단(500)을 더 구비할 수 있는데, 챔버 내부 공간에서 피검사자를 누인 상태로 지지시킬 수 있다.Although not shown in FIG. 9, as shown in FIG. 2, the chamber 40 may further include a human body supporting means 500, which may support the examinee in a state in which the examinee is in a lying state.
온도조절수단(300)은 본 발명의 일 양상에 따른 인체 발한 반응을 이용한 진단 시스템에 사용하는 것과 동일한 것을 사용할 수 있고, 챔버(40) 내에 구비되어 피검사자의 체온을 상승시켜 발한 반응을 유도하기 위한 것이다. 이러한 온도조절수단(300)은 복수의 발열수단으로 구성될 수 있으며, 대표적으로 상술한 열선 외에 코일형 히터, 온수 보일러 개념의 온수 파이프, 적외선, 근적외선 또는 원적외선 계열의 발광장치 및 PTC 등 열풍 발생장치 등이 있다.Temperature control means 300 may be the same as that used in the diagnostic system using the human body perspiration reaction according to an aspect of the present invention, is provided in the chamber 40 to increase the body temperature of the subject to induce a perspiration response will be. The temperature control means 300 may be composed of a plurality of heat generating means, typically a hot air generating device such as a coil-type heater, hot water pipes of the concept of hot water boiler, infrared, near infrared or far-infrared light emitting device and PTC in addition to the above-described heating wire Etc.
발한반응 검사수단(200)은 챔버(40) 내에 구비되어 피검사자사의 발열 및 발한반응을 측정하여 발열 및 발한 상태를 2차원 또는 3차원적으로 검출하는 것이고 인체 감시수단(400)은 챔버(40) 내에 구비되어 피검사자의 신체 상태를 실시간으로 검출하는 것이다. 이들 구성은 상술한 본 발명의 일 양상에 따른 인체 발한 반응을 이용한 진단 시스템에 사용하는 것과 동일한 것으로 사용할 수 있다. 또한 발한반응 검사수단(200)은 피검사자의 발한 상태뿐만 아니라 발열 상태를 2차원 및 3차원적으로 검출할 수 있도록 구동장치에 연결되어 위치와 각도가 조절될 수 있다. 발한반응 검사수단(200)에서 검출된 값(데이터)은 소프트웨어(700)로 전송되고 데이타를 분석하여 피검사자의 병소, 통증부위 및 통증정도를 진단하게 된다. The antiperspirant test means 200 is provided in the chamber 40 to measure the exothermic and perspiration reactions of the subject to detect the exothermic and perspiration conditions in two or three dimensions. The human body monitoring means 400 includes the chamber 40. It is provided inside to detect the physical condition of the subject in real time. These configurations can be used as the same as those used in the diagnostic system using the human body sweat response according to an aspect of the present invention described above. In addition, the perspiration test means 200 is connected to the driving device to detect the heating state as well as the heat state of the examinee in two dimensions and three dimensions can be adjusted in position and angle. The value (data) detected by the sweat perspiration test means 200 is transmitted to the software 700 to analyze the data to diagnose the lesion, pain area and pain degree of the subject.
챔버 내부 상태 센서부(600)는 챔버(40) 내에 구비되어 챔버 내부의 상태를 측정하는 구성요소로서, 챔버 내의 바람의 풍량과 풍속을 센싱하여 제어부(900)로 출력하는 풍향센서(600a), 챔버 내의 습도를 센싱하여 제어부(900)로 출력하는 습도센서(600b) 및 챔버 내의 온도를 센싱하여 제어부(900)로 출력하는 온도센서(600c)를 포함할 수 있고, 그 외 챔버 내부에 감지할 대상이 있는 경우 이를 감지할 수 있는 센서를 더 구비할 수 있다. The chamber internal state sensor 600 is a component provided in the chamber 40 to measure the state of the inside of the chamber. The wind direction sensor 600a senses and outputs the air volume and the wind speed in the chamber to the controller 900; It may include a humidity sensor (600b) for sensing the humidity in the chamber and outputs to the control unit 900 and a temperature sensor (600c) for sensing the temperature in the chamber and outputs to the control unit 900, and the other inside the chamber If there is an object may be further provided with a sensor for detecting it.
온도센서(600a)는 피검사자의 중심 온도 및 표면(피부) 온도와 챔버 내부의 온도를 측정할 수 있다. 이러한 온도센서는 챔버 내부의 온도(도 10, Ta)를 측정할 수 있는 챔버온도센서와 인체의 각 국소부위에 설치되어 인체의 중심 온도(도 10, Tc)와 부위별 피부 온도(도 10, Ts)를 측정할 수 있는 인체온도센서를 포함할 수 있다. 이러한 인체온도센서는 이마, 겨드랑이, 구강 및 귀에 투입하여 인체의 중심온도(도 10, Tc)를 검출하는 중심온도센서와 다리와 몸통 및 안면 등에 각각 부착하여 부위별 피부 온도(도 10, Ts)를 검출하는 피부온도센서로 이루어질 수 있다. 중심온도센서와 피부온도센서는 전자 체온계 또는 적외선 체온계가 될 수 있고, 이를 통해 이마, 겨드랑이, 구강, 귀, 다리와 몸통 등에 접촉식 또는 비접촉식으로 인체의 중심온도와 표면온도를 측정하여 그 값들을 통신부(미도시)를 통해 컴퓨터 소프트웨어에 제공한다. 이러한 온도의 측정은 카메라를 이용하여 측정할 수도 있다. The temperature sensor 600a may measure the center temperature and the surface (skin) temperature of the examinee and the temperature inside the chamber. Such a temperature sensor is installed in each chamber of the human body and a chamber temperature sensor capable of measuring the temperature inside the chamber (Fig. 10, Ta) and the central temperature of the human body (Fig. 10, Tc) and the skin temperature for each part (Fig. 10, It may include a human body temperature sensor that can measure Ts). The human body temperature sensor is attached to the forehead, armpits, mouth and ears to detect the central temperature of the human body (Fig. 10, Tc) and attached to the leg, torso and face, respectively, the skin temperature of each part (Fig. 10, Ts) It may be made of a skin temperature sensor to detect. The central temperature sensor and the skin temperature sensor may be electronic thermometers or infrared thermometers, and the center temperature and surface temperature of the human body may be measured by contact or noncontact with the forehead, armpits, mouth, ears, legs and torso. Provided to computer software through a communication unit (not shown). The measurement of this temperature may be measured using a camera.
습도센서(600b)는 챔버 내의 습도를 검출하고 풍향센서(600c)는 챔버 내의 바람의 풍량과 풍속을 검출한다.The humidity sensor 600b detects humidity in the chamber, and the wind direction sensor 600c detects air volume and wind speed of the wind in the chamber.
그 외 적외선 카메라, 온도 분포 측정 카메라 등을 통해 챔버의 공기 상태, 피검사자 상태를 모니터링하며 최적의 챔버 내부 조건으로 제어할 수 있다. 또한 다수의 카메라와 조명, 광학계 및 카메라의 위치/각도를 이동시키는 구동부를 가져 발한 상태의 2차원 및 3차원 측정을 가능하게 하며, 발한 상태를 판단하는 데이터를 확보할 수 있다.In addition, infrared cameras, temperature distribution cameras, etc. monitor the air condition of the chamber and the condition of the examinee, and can control the optimal internal chamber conditions. In addition, it has a plurality of cameras and illumination, optical system and a driving unit for moving the position / angle of the camera to enable two-dimensional and three-dimensional measurement of the sweating state, it is possible to secure the data to determine the sweating state.
이러한 센서를 통해 측정된 값은 소프트웨어(700)로 전송되고 각 조절부를 통해 온도, 습도 및 바람 등 진단기 내의 공기를 제어할 수 있다.The values measured by these sensors are transmitted to the software 700 and control the air in the diagnostic device such as temperature, humidity and wind through each control unit.
챔버 내부 상태 조절부(610)는 챔버 내부 상태 센서부(600)에 의해 측정된 챔버 내부의 상태를 조절하는 구성요소로서, 챔버 내의 습도를 조절하는 습도조절부(610b) 및 챔버 내의 바람의 풍량과 풍속을 조절하는 바람조절부(610a) 및 챔버 내의 온도를 조절하는 온도조절부(610c)를 포함할 수 있고, 그 외 필요한 상태를 센싱하는 센서에 의해 측정된 챔버 내부의 상태를 조절하는 조절부를 더 구비할 수 있다.The chamber internal condition adjusting unit 610 is a component for adjusting the state of the inside of the chamber measured by the chamber internal condition sensor unit 600, and the humidity control unit 610b for controlling the humidity in the chamber and the air volume of the wind in the chamber. It may include a wind controller 610a for adjusting the wind speed and the temperature controller 610c for controlling the temperature in the chamber, and controls to adjust the state of the inside of the chamber measured by the sensor for sensing other necessary conditions It may be further provided.
온도조절부(600a)는 상술한 온도조절수단(300)과 동일하거나 유사한 장치를 사용할 수 있다.The temperature control unit 600a may use the same or similar device as the above-described temperature control unit 300.
습도조절부(600b)는 각종의 습도조절장치, 예컨대 모세관 현상을 이용한 필터 방식의 공기 정화식 가습장치, 초음파식 가습장치, 가열식 가습장치, 제습장치 등을 사용할 수 있다.The humidity controller 600b may use various types of humidity controllers, for example, a filter-type air purifying humidifier, an ultrasonic humidifier, a heated humidifier, a dehumidifier, and the like using a capillary phenomenon.
바람조절부(600c)는 챔버 내의 바람의 풍량과 풍속을 조절하는 공기 조화장치 등을 사용할 수 있다. The wind control unit 600c may use an air conditioner for controlling the air volume and the wind speed in the chamber.
소프트웨어(700)는 발한반응 검사수단(200)로부터 측정된 데이타를 분석하여 피검사자의 병소, 통증부위 및 통증정도를 진단하는 구성요소이다. 즉, 컴퓨터에 수록될 수 있는 소프트웨어(700)는 RS-232C 및 USB와 같은 인터페이스를 통해 챔버로부터 받은 정보를 컴퓨터에 실시간으로 저장하고 분석하는 기능을 수행하게 되는데, 챔버 내부에 장착된 카메라를 제어하여 정해진 시간 간격으로 피검사자의 사진을 찍어 데이터베이스에 저장하며, 이미지 프로세싱을 통해 피검사자의 발한 패턴을 분석할 수 있다. 소프트웨어적으로 3차원 표면 형상에 대한 발한 상태를 얻어 이를 2차원 면적에 대해서 발한 정도의 표현으로 보정을 하여 단위 면적당의 발한 상태 값으로 표현을 하며, 발한 상태의 데이터베이스를 구성하고 이에 저장된 데이터를 2차원 또는 3차원의 인체 모형 더미 위에 발한 위치, 발한 양 및 발한 분포를 표시하되, 피검사자의 발열온도, 시간, 투입 가열 온도 등의 데이터를 다수의 시간별로 확보하여, 피검사자의 발열 및 발한 특성을 파악하고, 파악한 발한 및 발열 특성은 추후에 재검사할 때, 이를 기준으로 피검사자별 맞춤 측정을 가능하도록 한다. 아울러 피검사자의 치유 정도에 따른 비교 데이터 또한 확보할 수 있다. The software 700 is a component for diagnosing the lesion, pain area, and pain degree of the examinee by analyzing data measured from the sweating test means 200. That is, the software 700 that can be stored in the computer performs a function of storing and analyzing information received from the chamber in real time in a computer through an interface such as RS-232C and USB, and controlling a camera mounted in the chamber. By taking a picture of the subject at a predetermined time interval and storing it in the database, the sweat pattern of the subject can be analyzed through image processing. The software obtains the sweating state of the 3D surface shape and corrects it with the expression of sweating degree for the 2D area and expresses it as the sweating state value per unit area, constructs a database of sweating state, and stores the data stored therein. The location of sweating, the amount of sweating, and the distribution of sweating are displayed on the dummy of the 3D or 3D human body, and the data of the subject's heat generation temperature, time, input heating temperature, etc. are secured for a plurality of times to identify the subject's heat generation and sweating characteristics. In addition, the sweating and fever characteristics which have been identified will enable a personalized measurement for each subject on the basis of retesting later. In addition, comparative data according to the degree of healing of the examinee can be obtained.
디스플레이부(800)는 인체 모형을 사용하여 소프트웨어(700)에 의해 진단된 결과를 2차원 또는 3차원적으로 디스플레이하는 구성요소이다. The display 800 is a component that displays the results diagnosed by the software 700 in two or three dimensions using a human body model.
본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치의 제어부에 대한 기능을 설명하는 도면인 도 11로부터, 제어부(900)는 발한반응 검사수단(200), 인체 감시수단(400), 챔버 내부 상태 조절부(610), 소프트웨어(700) 및 디스플레이부(800)을 제어하는 구성요소이며, 이들 구성요소간의 데이터를 전송 및 수신할 수 있는 유무선 통신 수단(미도시)을 더 제어할 수 있음은 물론이다.11 is a view illustrating a function of a control unit of a diagnostic apparatus using a human body antiperspirant according to another aspect of the present invention, the control unit 900 is an antiperspirant test means 200, a human body monitoring means 400, the chamber interior It is a component that controls the state control unit 610, software 700 and the display unit 800, and can further control wired and wireless communication means (not shown) that can transmit and receive data between these components Of course.
또한 본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치는 피검사자의 과거 발한 반응 데이터를 구비하는 데이터베이스부를 더 포함하고, 제어부(900)는 과거 발한 반응 데이터가 존재하는 경우 이러한 데이터를 이용하여 발한 측정 시간을 최소화할 수 있도록 상기 온도조절수단(300)을 제어할 수 있다.In addition, the diagnostic apparatus using the human body perspiration reaction according to another aspect of the present invention further includes a database unit having the past perspiration response data of the examinee, the control unit 900 using the data if the past perspiration response data is present The temperature adjusting means 300 may be controlled to minimize the measurement time.
또한 제어부(900)는 피검사자의 전체 발열 면적을 다수의 소 면적 모듈로 구분하고 각 모듈 하단에 다수의 센서 및 카메라를 장착하여 온도 분포를 측정한 다음 국소 피부 표면 온도가 설정치 이상으로 높아지는 것을 방지하여 안전한 진단이 가능하도록 제어할 수 있다.In addition, the control unit 900 divides the entire heating area of the examinee into a plurality of small area modules, measures a temperature distribution by mounting a plurality of sensors and cameras at the bottom of each module, and then prevents the local skin surface temperature from rising above a set value. It can be controlled to enable safe diagnosis.
이러한 본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치의 작동 과정을 나타낸 플로우차트인 도 12를 사용하여 인체 발한 반응을 이용한 진단 장치의 작동 과정을 설명한다.The operation of the diagnosis apparatus using the human body sweat response will be described using FIG. 12, which is a flowchart illustrating the operation of the diagnosis apparatus using the human body sweat response according to another aspect of the present invention.
먼저, 시작과 함께 스위치를 켜면 검진의 시작 여부를 묻고, 검진 시작이면 피검사자의 정보를 입력한다. 이때 피검사자의 정보는 예컨대 피검사자의 주민등록번호나 검사 요청 시 제공한 피검사자의 관리번호 등 피검사자를 확인할 수 있는 정보이면 어느 것이나 상관없다.First, when the switch is turned on with the start, it asks whether the examination is to be started, and if the examination is started, the information of the examinee is input. At this time, the information of the examinee may be any information that can identify the examinee, such as the resident registration number of the examinee or the control number of the examinee provided when the inspection is requested.
다음으로 피검사자의 과거 발한 반응 데이터, 즉 당해 검사 전에 검사를 한 이전의 발한 및 발열 특성 데이터가 있는 경우, 온도센서, 습도센서 및 풍향센서가 작동하여 이들 값이 검출되면 제어부는 과거 발한 반응 데이터에 맞게 챔버 내의 온도, 습도 및 바람을 조절하고 또한 온도조절수단을 이용하여 피검사자의 체온을 상승시켜 발한 반응을 유도한다. 이 경우 피검사자의 과거 발한 반응 데이터가 있기 때문에 제어부는 피검사자의 최초 발한 특성까지 빠르게 발열시키고 챔버 내의 온도, 습도 및 바람을 빠르게 제어할 수 있는 장점을 가질 수 있다.Next, if there is historical sweating data of the examinee, that is, the sweating and exothermic characteristics data of the previous test before the test, if the temperature sensor, humidity sensor, and wind direction sensor are detected, and these values are detected, the control unit will check the past sweating data. The temperature, humidity and wind in the chamber are adjusted accordingly, and the body temperature of the subject is raised by using a temperature control means to induce a perspiration reaction. In this case, since there is historical sweating data of the examinee, the controller may have an advantage of rapidly heating the first sweating characteristic of the examinee and rapidly controlling temperature, humidity, and wind in the chamber.
만약 피검사자의 과거 발한 반응 데이터가 없는 경우, 즉 처음 검진하는 피검사자인 경우 챔버 환경 상태를 미리 설정한 다음 풍향센서, 습도센서 및 온도센서의 감지 신호를 제공받아 미리 설정된 바람, 습도 및 온도 데이터와 비교하여 바람조절부, 습도조절부 및 온도조절부를 제어하여 챔버 내부를 적절한 환경으로 맞춘다. 아울러 제어부는 온도조절수단을 통해 피검사자의 체온을 상승시켜 발한 반응을 유도할 수 있도록 인체 피부 온도와 중심 온도를 소정의 온도까지 상승시킨다.If there is no past response data of the examinee, that is, the first examinee, the condition of the chamber is set in advance, and the detection signals of the wind direction sensor, humidity sensor, and temperature sensor are provided and compared with the preset wind, humidity, and temperature data. By controlling the wind control unit, humidity control unit and temperature control unit to adjust the interior of the chamber to the appropriate environment. In addition, the control unit increases the human skin temperature and the center temperature to a predetermined temperature so as to increase the body temperature of the subject through the temperature control means to induce a sweating response.
이 때, 센서들의 작동에 이상이 있는 경우 측정을 중단하고 알람 신호를 발생시켜 검사자 또는 피검사자가 인식하여 안전을 도모할 수 있도록 한다.At this time, if there is an error in the operation of the sensor, the measurement is stopped and an alarm signal is generated so that the inspector or inspectee can recognize and promote safety.
다음으로, 제어부는 피부온도센서와 중심온도센서로부터 출력되는 피검사자의 피부온도(도 10, Ts) 및 중심온도(도 10, Tc) 데이터를 수집하고, 그 온도 데이터를 주기적으로 컴퓨터로 보고한다.Next, the controller collects the skin temperature (FIG. 10, Ts) and the center temperature (FIG. 10, Tc) data of the examinee output from the skin temperature sensor and the central temperature sensor, and periodically reports the temperature data to a computer.
컴퓨터는 제어부로부터 실시간으로 전송되는 챔버의 내부 온도(도 10, Ta)등 내부 환경 및 환자의 피부온도와 중심온도에 대한 데이터를 수집하여 데이터베이스에 저장함과 아울러 설정된 시간 간격으로 카메라를 제어하여 복수의 카메라로부터 각각 전송되는 피검사자의 상체 및 하체의 발한 패턴을 제공받아 데이터베이스에 저장한다.The computer collects data on the internal environment, such as the internal temperature of the chamber (FIG. 10, Ta) transmitted from the controller in real time, the skin temperature and the center temperature of the patient, and stores the data in a database, and controls the camera at a set time interval. The upper and lower body sweat patterns are transmitted from the camera and stored in the database.
다음으로, 컴퓨터는 제어부로부터 전송되는 중심온도 데이터를 제공받아 중심온도가 설정한 온도까지 상승되었는지를 판단하고, 미리 설정된 온도, 예컨대 38 내지 38.4℃에 도달할 경우, 컴퓨터는 검진 종료명령을 제어부로 전송하며, 수집된 피검사자의 사진을 이미지 프로세싱하여 발한 패턴을 수치화한 후 데이터베이스에 저장한다.Next, the computer receives the center temperature data transmitted from the control unit to determine whether the center temperature has risen to the set temperature, and when the temperature reaches a preset temperature, for example, 38 to 38.4 ° C., the computer sends a check end command to the control unit. The image of the collected test subject is image-processed and the pattern is quantified and stored in a database.
그 밖에, 제어부는 컴퓨터의 검진종료 명령에 따라 온도조절수단, 온도조절부, 습도조절부, 바람조절부 및 기타 센서와 카메라의 작동을 중지시킬 수 있음은 물론이다.In addition, the control unit may stop the operation of the temperature control unit, the temperature control unit, the humidity control unit, the wind control unit and other sensors and the camera according to the end of the examination of the computer.
본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치의 카메라 등의 광학계와 구동장치를 설명하는 도 13는 모아레 격자 무늬를 피검사자에게 투영하여 기준 격자무늬와의 간섭 또는 비교를 통하여 그 변화를 감지하여 3차원적으로 발한정도를 측정하는 광학계의 예인데, 정확한 측정을 위해 카메라부 일부의 위치와 각도를 제어할 수 있는 구동부를 가지는 측정 카메라를 도시한 것이다.13 illustrates an optical system such as a camera of a diagnostic apparatus using a perspiration reaction according to another aspect of the present invention, and a driving device to project a moire lattice onto an examinee to detect the change through interference or comparison with a reference lattice pattern. This is an example of an optical system for measuring the degree of sweating in three dimensions, it shows a measuring camera having a drive unit for controlling the position and angle of a portion of the camera for accurate measurement.
인체 발한 반응을 이용한 진단 장치은 기본적으로 다수의 측정 카메라를 통해 발한 상태의 데이터를 확보하는데, 3차원 영상과 피부 표면에 평행한 2차원 영상을 데이터베이스의 기초 영상으로 이용한다. Diagnosis device using the human perspiration reaction basically secures the data of the sweating state through a plurality of measuring cameras, using a three-dimensional image and a two-dimensional image parallel to the skin surface as the base image of the database.
한편, 발색 시약을 바르고 얻는 발한 패턴의 영상에 있어서도 옆면이나 경사면의 경우 다수 카메라의 위치와 각도를 구동장치를 통한 구동 제어를 통해 피부 표면에 평행한 면의 영상을 얻는 것이 가능하다. 이러한 다수 카메라의 위치와 각도를 제어하여 3차원 영상을 얻는데, 스테레오 비젼을 이용한 입체영상, 모아레 간섭무늬나 땀 위치의 간섭무늬를 통한 발한 상태의 3차원 측정 영상, 시약을 바르고 발한 패턴을 측정하는 영상 또는 광학식 3차원 높이 데이터를 얻는 입체영상 등 진단에 적합한 다양한 영상을 확보하는 것이 가능하다. 이렇게 확보한 영상을 기초로 3차원 영상을 추출하고, 3차원 표면 형상에 대한 2차원 표면적의 발한 상태를 소프트웨어적으로 추출하여 데이터베이스화할 수 있다.On the other hand, even in the image of the sweat pattern obtained by applying the coloring reagent, it is possible to obtain an image of a surface parallel to the surface of the skin through the drive control of the position and angle of the multiple cameras in the case of the side surface or the inclined surface. The three-dimensional image is obtained by controlling the positions and angles of the plurality of cameras. The three-dimensional image using stereo vision, the three-dimensional measurement image of sweating state through the moiré interference pattern or the interference pattern at the sweat position, and applying the reagent and measuring the sweating pattern It is possible to secure a variety of images suitable for diagnosis, such as stereoscopic images that obtain images or optical three-dimensional height data. The 3D image can be extracted based on the obtained image, and the sweating state of the 2D surface area with respect to the 3D surface shape can be extracted and softwareized.
본 발명의 다른 양상에 따른 인체 발한 반응을 이용한 진단 장치의 디스플레이부에서 표시되는 예를 설명하는 도면인 도 14로부터, 발한 특성을 표시하는 디스플레이 표현 방법을 확인할 수 있다.A display representation method of displaying sweating characteristics can be seen from FIG. 14, which is a view for explaining an example displayed on a display unit of a diagnostic apparatus using a human sweating response according to another aspect of the present invention.
소프트웨어(700)는 피검사자의 발한 위치, 발한 양 및 발한 분포 등의 발한 특성값을 3차원 표면 형상에 대해 얻은 다음, 이를 2차원 노출 표면적에 대한 평균 발한 특성값으로 보정한 후 발한 위치, 발한 양 및 발한 분포 등의 발한 특성값을 2차원 또는 3차원의 인체 모형 더미가 표현되어 있는 상기 디스플레이부(800)에 표시할 수 있다. 즉, 발한 특성을 2차원 또는 3차원 인체 모형 위에 그 위치, 양, 분포(패턴)를 점, 색 및/또는 형상 등을 이용하여 디스플레이부에 표현할 수 있다. 발한 특성은 발한 시간을 더 포함할 수도 있다. The software 700 obtains perspiration characteristic values, such as perspiration position, perspiration amount, and perspiration distribution, for a three-dimensional surface shape, and then corrects them with an average perspiration characteristic value for a two-dimensional exposed surface area, followed by perspiration position, perspiration amount. And perspiration characteristic values such as perspiration distribution on the display unit 800 in which a dummy of two-dimensional or three-dimensional human models is represented. That is, the sweating characteristic may be expressed on the display unit by using a point, color, and / or shape such as the position, quantity, and distribution (pattern) on the 2D or 3D human body model. The sweating characteristic may further comprise a sweating time.
또한 디스플레이부에 표현되어 있는 인체 모형 더미는 디스플레이부의 부위별 클릭이나 터치에 의해 클릭 또는 터치된 부위가 회전 및 확대되거나 해당 부위의 상세한 발한 정보를 제공될 수도 있다. 즉 디스플레이부에 표현되어 있는 인체 모형 더미의 특정 위치를 클릭하거나 터치하면, 특정 위치의 영상을 회전하거나 확대할 수 있고 또한 해당 위치의 상세한 발한 정보를 디스플레이할 수 있다.In addition, the dummy dummy represented in the display unit may be rotated and enlarged or clicked or touched by a click or touch for each part of the display unit or provide detailed sweating information of the corresponding part. That is, when a user clicks or touches a specific position of the dummy dummy represented in the display unit, the image of the specific position can be rotated or enlarged and detailed sweating information of the corresponding position can be displayed.
이상에서 살펴본 바와 같은 본 발명의 다른 양상에 따르면, 다수 카메라의 위치와 각도를 제어하여 영상을 얻는 방법을 통해 3차원 영상을 얻어 분석하거나 이로부터 2차원 표면적에 대한 정확한 영상을 얻을 수 있어, 단위 표면적 대비 발한 양의 상태값으로 보정이 가능한 장점을 가지게 된다. According to another aspect of the present invention as described above, by obtaining the image by controlling the position and angle of a plurality of cameras to obtain a three-dimensional image or to obtain an accurate image of the two-dimensional surface area from this unit, It has the advantage that it can be corrected by the state value of sweating against surface area.
또한 발색 시약의 사용 없이 발한의 정도를 시간에 따라 데이터화하므로, 각 부위별 총 발한 양, 발한 시간, 부위별 최초 발한 조건 및 발한 특성의 변화 등에 대해 종합적인 정보를 얻을 수 있어 기존의 패턴 검사만으로 알아내기 어려웠던 많은 분석들이 가능해진다.In addition, since the degree of sweating is dataized over time without using a coloring reagent, comprehensive information on total sweating amount, sweating time, initial sweating conditions and sweating characteristics of each part can be obtained. Many analyzes that have been difficult to figure out are possible.
또한 본 발명의 다른 양상에 따르면, 발열수단, 센서, 측정기, 분석 컴퓨터 등으로 구성되어 시스템화가 가능하고, 통신 등을 통해 원격 진료 등도 가능해지며, 상대적으로 저렴하고 편리성이 높은 장치를 구성할 수 있다. 또한 발열 및 발한 상태를 검출하여 발한 양, 발한 시간, 최초 발한 특성 및 발한의 시간적 변화 특성, 온도, 습도에 따른 변화특성 등을 분석하는 시스템화 기법을 통해 피검사자의 병소와 통증부위, 통증정도를 간단하고 정확하며 반복 재현성 높게 진단할 수 있어 사용자의 편의성과 효율성이 한층 높아지게 되며, 자율 신경 기능의 관찰이 안정적으로 가능하며, 연속적인 변화의 관찰, 굵기가 가는 비유수신경 검사, 장애인의 검사 및 말초 신경계의 손상 검사가 가능하다.In addition, according to another aspect of the present invention, it is composed of a heating means, a sensor, a measuring instrument, an analysis computer, etc., it is possible to systemize, remote communication through communication, etc., it is possible to constitute a relatively inexpensive and convenient device have. In addition, systemic techniques for detecting fever and sweating conditions, such as sweating amount, sweating time, initial sweating characteristics and temporal change characteristics of sweating, and changes according to temperature and humidity can be used to simplify lesions, pain areas, and pain levels of subjects. It can be diagnosed with high accuracy, repeatability and high reproducibility, which makes the user's convenience and efficiency more stable, and it is possible to observe autonomic nerves stably, and to observe continuous changes, thin non-influential neuropsy, examination of the disabled and peripheral Nervous system damage testing is possible.
이상의 설명은 본 발명의 기술 사상을 예시적으로 설명한 것에 불과한 것으로서, 본 발명이 속하는 기술 분야에서 통상의 지식을 가진 자라면 본 발명의 본질적인 특성에서 벗어나지 않는 범위에서 다양한 수정 및 변형이 가능할 것이다. 따라서 본 발명에 기재된 실시예들은 본 발명의 기술 사상을 한정하기 위한 것이 아니라 설명하기 위한 것이고, 이러한 실시예에 의하여 본 발명의 기술 사상이 한정되는 것은 아니다. 본 발명의 보호 범위는 아래의 청구범위에 의해서 해석되어야하며, 그와 동등한 범위 내에 있는 모든 기술 사상은 본 발명의 권리범위에 포함되는 것으로 해석되어야 할 것이다.The above description is merely illustrative of the technical idea of the present invention, and those skilled in the art to which the present invention pertains may make various modifications and changes without departing from the essential characteristics of the present invention. Therefore, the embodiments described in the present invention are not intended to limit the technical idea of the present invention but to explain, and the technical idea of the present invention is not limited by these embodiments. The protection scope of the present invention should be interpreted by the following claims, and all technical ideas within the scope equivalent thereto should be construed as being included in the scope of the present invention.
본 발명은 발색시약을 이용하지 않고 피검사자의 피부에 대한 광조사를 통해 발한반응에 대한 검사를 진행할 수 있어 피검사자의 피부 전체에 시약을 바름에 따라 피검사자가 거부감을 크게 느끼는 문제점을 해결하고 또한 검사 후 피검사자의 인체가 시약으로 더러워진 불결한 상태가 되는 문제점을 해결할 수 있는 인체 발한 반응을 이용한 진단 시스템과 일상적인 환경과 같은 편안한 상태에서 피검사자를 빠르고 정확하게 진단할 수 있고, 발한의 특징 분석을 통한 진단과 인체모형 더미 위에 표시되는 디스플레이 방식을 통해 피검사자의 병소와 통증부위, 통증 정도를 알 수 있어 검사의 편의성과 효율성을 동시에 추구할 수 있는 인체 발한 반응을 이용한 진단 장치 등의 산업에 유용하게 이용할 수 있다.The present invention can proceed the test for the sweating reaction by irradiating the skin of the examinee without using a coloring reagent, solve the problem that the subject feels a great sense of rejection by applying the reagent to the entire skin of the subject and after the test Diagnosis system using the human perspiration reaction to solve the problem that the subject's body becomes dirty with reagents, and can quickly and accurately diagnose the subject in a comfortable condition such as a daily environment, and diagnosis through the characterization of sweating and the human body The display method displayed on the dummy can identify the subject's lesion, pain area, and pain level, which can be usefully used in industries such as diagnostic devices using human perspiration, which can simultaneously pursue convenience and efficiency.

Claims (20)

  1. 열 조절에 의한 피검사자의 발한반응을 검사하기 위한 시스템으로서,A system for examining the sweating response of the subject by heat control,
    피검사자의 체온을 상승시켜 발한 반응을 유도하기 위한 온도조절수단;Temperature control means for inducing a perspiration response by raising the body temperature of the subject;
    상기 피검사자의 피부로 광을 조사하는 광 조사수단;Light irradiation means for irradiating light to the skin of the examinee;
    상기 피검사자의 피부로부터 반사 광을 수집하는 광 측정수단; 및Light measuring means for collecting the reflected light from the skin of the examinee; And
    상기 광 측정수단에서 수집한 반사 광의 광량 변화 또는 광강도 분포를 기초로 상기 피검사자의 발한 반응을 측정하는 인체 진단수단을 포함하는 것을 특징으로 하는 인체 발한 반응을 이용한 진단 시스템.And a human body diagnosing means for measuring an antiperspirant response of the subject based on a change in light quantity or light intensity distribution of the reflected light collected by the optical measuring means.
  2. 제 1 항에 있어서,The method of claim 1,
    상기 광 조사수단은,The light irradiation means,
    가시광을 발생시켜 상기 피검사자의 피부로 조사하는 광원부를 포함하고,A light source unit generating visible light and irradiating the skin of the examinee;
    상기 광 측정수단은,The optical measuring means,
    상기 피검사자의 피부로부터 반사되는 가시광을 감지하는 광센서, 카메라 또는 광센서와 카메라를 포함하는 수광부를 포함하며, 상기 가시광의 반사광에 대한 광량을 기초로 상기 피검사자의 발한 반응을 측정하는 것을 특징으로 하는 인체 발한 반응을 이용한 진단 시스템.And a light sensor for detecting visible light reflected from the skin of the examinee, a light receiving unit including a light sensor and a camera, and measuring an sweat sweating response of the examinee based on the amount of light with respect to the reflected light of the visible light. Diagnosis system using human perspiration.
  3. 제 1 항에 있어서,The method of claim 1,
    상기 광 조사수단은,The light irradiation means,
    적외선광을 발생시켜 상기 피검사자의 피부로 조사하는 광원부를 포함하고,A light source unit generating infrared light and irradiating the skin of the examinee;
    상기 광 측정수단은,The optical measuring means,
    상기 피검사자의 피부로부터 반사되는 적외선광을 감지하는 적외선 광센서, 적외선 카메라 또는 적외선 광센서와 적외선 카메라를 포함하는 수광부를 포함하며, 상기 적외선광의 반사광에 대한 광량을 기초로 상기 피검사자의 발한 반응을 측정하는 것을 특징으로 하는 인체 발한 반응을 이용한 진단 시스템.An infrared light sensor, an infrared camera, or an infrared light sensor for detecting infrared light reflected from the skin of the examinee, and a light receiver including an infrared light sensor and an infrared camera, the sweat perception of the subject being measured based on the amount of light to the reflected light of the infrared light; Diagnosis system using the human body sweat response, characterized in that.
  4. 제 1 항에 있어서,The method of claim 1,
    상기 광 조사수단은,The light irradiation means,
    자외선광을 발생시켜 상기 피검사자의 피부로 조사하는 광원부를 포함하고,A light source unit generating ultraviolet light and irradiating the skin of the examinee;
    상기 광 측정수단은,The optical measuring means,
    상기 피검사자의 피부로부터 반사되는 자외선광을 감지하는 자외선 광센서, 자외선 카메라 또는 자외선 광센서와 자외선 카메라를 포함하는 수광부를 포함하며, 상기 적외선광의 반사광 또는 간섭광에 대한 광량을 기초로 상기 피검사자의 발한 반응을 측정하는 것을 특징으로 하는 인체 발한 반응을 이용한 진단 시스템.An ultraviolet light sensor for detecting ultraviolet light reflected from the skin of the examinee, an ultraviolet camera, or a light receiving unit including an ultraviolet light sensor and an ultraviolet camera, the sweating of the examinee based on the amount of light to the reflected light or the interference light of the infrared light; Diagnosis system using the human perspiration response, characterized in that for measuring the response.
  5. 제 1 항에 있어서,The method of claim 1,
    상기 광 조사수단와 상기 광 측정수단는 하나의 하우징에 일체형으로 형성된 것을 특징으로 하는 인체 발한 반응을 이용한 진단 시스템.The light irradiation means and the light measuring means is a diagnostic system using the human body perspiration reaction, characterized in that formed in one housing.
  6. 제 1 항 내지 제 5 항 중 어느 한 항에 있어서,The method according to any one of claims 1 to 5,
    상기 광 조사수단은, 복수개의 광원부를 포함하고,The light irradiation means includes a plurality of light sources,
    각각의 광원부는 상기 피검사자의 서로 다른 피부 부위로 광을 조사하며,Each light source irradiates light to different skin parts of the examinee,
    상기 광 측정수단은,The optical measuring means,
    상기 복수개의 광원부에 대응하여 상기 피검사자의 피부로부터 반사 광을 수집하는 복수개의 수광부를 포함하는 것을 특징으로 하는 인체 발한 반응을 이용한 진단 시스템.And a plurality of light receiving units collecting reflected light from the skin of the examinee in correspondence with the plurality of light source units.
  7. 제 1 항에 있어서,The method of claim 1,
    상기 피검사자의 인체에 대응하여 상기 광 조사수단과 상기 광 측정수단을 수평 방향 또는 수직 방향으로 이송시키는 이송수단을 더 포함하며,And a transfer means for transferring the light irradiation means and the light measuring means in a horizontal direction or a vertical direction corresponding to the human body of the examinee.
    상기 광 조사수단은 상기 이송수단을 통해 상기 피검사자의 피부의 전체 또는 일부분을 이동하면서 광을 조사하고, The light irradiation means is irradiated with light while moving the whole or part of the skin of the examinee through the transfer means,
    상기 광 측정수단은 상기 광 조사수단의 이동에 대응하여 이동하면서 상기 피검사자의 피부로부터 반사 광을 수집하는 것을 특징으로 하는 인체 발한 반응을 이용한 진단 시스템.And the light measuring means collects reflected light from the skin of the examinee while moving in response to the movement of the light irradiation means.
  8. 제 1 항에 있어서,The method of claim 1,
    상기 피검사자의 인체를 중심으로 상기 광 조사수단과 상기 광 측정수단를 회전시키는 회전수단을 더 포함하며,Rotating means for rotating the light irradiation means and the light measuring means about the human body of the examinee,
    상기 광 조사수단은 상기 피검사자의 인체를 중심으로 회전하면서 상기 피검사자의 피부의 전체 또는 일부분에 광을 조사하고, The light irradiation means is irradiated with light to the whole or part of the skin of the subject while rotating about the human body of the subject,
    상기 광 측정수단은 상기 광 조사수단의 이동에 대응하여 회전하면서 상기 피검사자의 피부로부터 반사 광을 수집하는 것을 특징으로 하는 인체 발한 반응을 이용한 진단 시스템.And the light measuring means collects reflected light from the skin of the examinee while rotating in response to the movement of the light irradiation means.
  9. 제 7 항 또는 제 8 항에 있어서,The method according to claim 7 or 8,
    상기 광 조사수단은 상기 피검사자의 인체의 상면, 하면 및 측면의 피부로 광을 조사하고,The light irradiation means is irradiated with light to the skin of the upper, lower and side surfaces of the human body of the examinee,
    상기 광 측정수단은 상기 광 조사수단의 광 조사에 대응하여 상기 피검사자의 인체의 상면, 하면 및 측면의 피부로터의 반사 광을 수집하며,The light measuring means collects the reflected light of the skin rotor of the upper, lower and side surfaces of the human body of the examinee in response to the light irradiation of the light irradiation means,
    상기 인체 검사수단은 상기 피검사자의 인체에 대하여 3차원적으로 발한 상태를 측정하는 것을 특징으로 하는 인체 발한 반응을 이용한 진단 시스템.The human body inspection means is a diagnostic system using the human body perspiration reaction characterized in that for measuring the state of sweating on the human body of the examinee.
  10. 제 1 항 내지 제 8 항 중 어느 한 항에 있어서,The method according to any one of claims 1 to 8,
    상기 피검사자를 공간 상에서 누운 상태로 지지시키기 위한 인체 지지수단을 더 포함하며,Further comprising a human body support means for supporting the subject in a state of lying in the space,
    상기 인체 지지수단은,The human body support means,
    광이 투과 가능한 투명 재질 베드, 매쉬형태의 그물망 베드 또는 복수개의 봉이 일정간격씩 평행하게 이격되어 위치된 평행봉 베드를 포함하는 것을 특징으로 하는 인체 발한 반응을 이용한 진단 시스템.Diagnosis system using the human body perspiration reaction comprising a transparent material bed, a mesh-type mesh bed or a plurality of rods are parallel bars spaced apart in parallel by a predetermined interval.
  11. 제 10 항에 있어서,The method of claim 10,
    상기 인체 지지수단은,The human body support means,
    투명 유리 또는 투명 플라스틱으로 형성된 것을 특징으로 하는 인체 발한 반응을 이용한 진단 시스템.Diagnosis system using the human perspiration reaction, characterized in that formed of transparent glass or transparent plastic.
  12. 소정의 검진을 받기 위해 피검사자가 누울 공간이 형성된 챔버(40)와,A chamber 40 in which a space for the examinee to lie down is formed to receive a predetermined examination;
    상기 챔버(40) 내에 구비되어 피검사자의 체온을 상승시켜 발한 반응을 유도하기 위한 온도조절수단(300)과,It is provided in the chamber 40 and the temperature control means 300 for inducing a perspiration reaction by raising the body temperature of the examinee,
    상기 챔버(40) 내에 구비되어 피검사자사의 발한반응을 측정하는 발한반응 검사수단(200)과, An antiperspirant test means 200 provided in the chamber 40 to measure an antiperspirant response of the test subject;
    상기 챔버(40) 내에 구비되어 피검사자의 신체 상태를 실시간으로 검출하는 인체 감시수단(400)과,A human body monitoring means 400 provided in the chamber 40 to detect a physical state of a subject in real time;
    상기 챔버(40) 내에 구비되어 챔버 내부의 상태를 검출하는 챔버 내부 상태 센서부(600)와;A chamber internal state sensor unit 600 provided in the chamber 40 to detect a state inside the chamber;
    상기 챔버 내부 상태 센서부(600)에 의해 검출된 챔버 내부의 상태를 조절하는 챔버 내부 상태 조절부(610)와,A chamber internal state controller 610 for controlling a state inside the chamber detected by the chamber state sensor unit 600;
    상기 발한반응 검사수단(200)로부터 측정된 데이타를 분석하여 피검사자의 병소, 통증부위 및 통증정도를 진단하는 소프트웨어(700)와, Software 700 for diagnosing the lesion, pain area and pain degree of the examinee by analyzing the data measured from the sweat response test means 200,
    상기 소프트웨어(700)에 의해 진단된 결과를 2차원 또는 3차원적으로 인체 모형을 사용하여 디스플레이하는 디스플레이부(800)와,A display unit 800 for displaying a result diagnosed by the software 700 using a human body in two or three dimensions;
    상기 발한반응 검사수단(200), 상기 인체 감시수단(400), 상기 챔버 내부 상태 조절부(610), 상기 소프트웨어(700) 및 상기 디스플레이부(800)을 제어하는 제어부(900)을 포함하는, 인체 발한 반응을 이용한 진단 장치.It includes a control unit 900 for controlling the sweating response means 200, the human body monitoring means 400, the internal state control unit 610, the software 700 and the display unit 800, Diagnostic device using the human body sweating.
  13. 제12항에 있어서,The method of claim 12,
    상기 챔버(40)는 피검사자의 출입이 용이하도록 상기 챔버의 상단에 형성된 고리(41)에 회동가능하게 결착된 투명창(42)과 상기 투명창(42)을 상기 챔버의 하단에 체결하는 체결부(43)를 포함하고,The chamber 40 is a fastening part for fastening the transparent window 42 and the transparent window 42 which are rotatably fastened to the ring 41 formed on the upper end of the chamber to facilitate the entrance and exit of the examinee. Including 43,
    상기 챔버(40)를 지지하는 챔버 지지대(30)를 더 포함하는, 인체 발한 반응을 이용한 진단 장치.Further comprising a chamber support (30) for supporting the chamber (40), the diagnostic device using the human body perspiration reaction.
  14. 제12항에 있어서,The method of claim 12,
    상기 챔버 내부 상태 센서부(600)는 챔버 내의 바람의 풍량과 풍속을 센싱하여 제어부(900)로 출력하는 풍향센서(600c), 챔버 내의 습도를 센싱하여 제어부(900)로 출력하는 습도센서(600b) 및 챔버 내의 온도를 센싱하여 제어부(900)로 출력하는 온도센서(600a)를 포함하고,The chamber internal state sensor 600 is a wind direction sensor 600c for sensing the air volume and the wind speed of the wind in the chamber and outputs it to the control unit 900, a humidity sensor 600b for sensing the humidity in the chamber and outputs it to the control unit 900 And a temperature sensor 600a for sensing the temperature in the chamber and outputting the temperature to the controller 900.
    상기 챔버 내부 상태 조절부(610)는 챔버 내의 바람의 풍량과 풍속을 조절하는 바람조절부(600c), 챔버 내의 습도를 조절하는 습도조절부(600b) 및 챔버 내의 온도를 조절하는 온도조절부(600a)를 포함하는, 인체 발한 반응을 이용한 진단 장치.The chamber internal condition controller 610 is a wind controller 600c for controlling the air volume and wind speed of the chamber, a humidity controller 600b for controlling the humidity in the chamber and a temperature controller for controlling the temperature in the chamber ( 600a), the diagnostic device using the human body perspiration reaction.
  15. 제12항에 있어서,The method of claim 12,
    상기 발한반응 검사수단(200)은 피검사자의 발열 및 발한 상태를 2차원 및 3차원적으로 검출하기 위해 구동장치에 연결되어 있는, 인체 발한 반응을 이용한 진단 장치.The perspiration test means 200 is connected to the driving device for detecting the heat and sweating state of the subject in two and three dimensions, the diagnostic device using the human perspiration reaction.
  16. 제12항에 있어서, The method of claim 12,
    피검사자의 과거 발한 반응 데이터를 구비하는 데이터베이스부를 더 포함하고, 상기 제어부(900)은 상기 과거 발한 반응 데이터가 존재하는 경우 상기 데이터를 이용하여 발한 측정 시간을 최소화할 수 있도록 상기 온도조절수단(300)을 제어하는, 인체 발한 반응을 이용한 진단 장치.The apparatus may further include a database including past perspiration response data of the examinee, and the control unit 900 may minimize the perspiration measurement time by using the data when the past perspiration response data exists. To control the diagnosis device using the human body perspiration reaction.
  17. 제16항에 있어서,The method of claim 16,
    상기 과거 발한 반응 데이터는 피검사자의 시간에 따른 발한 특성값, 발한 분포값, 발열온도에 따른 발한 특성갑, 발열 시간에 따른 발한 특성값, 피검사자의 시간에 따른 치유 정도값, 개인별 발한 양의 차이에 따라 절대값이 아닌 상대값으로 환자의 신체 부위별 발한 비율 등의 데이터를 제공하는 것을 특징으로 하는 피부 발한 반응을 이용한 진단장치.The past perspiration response data includes the perspiration characteristics value, perspiration distribution value, the perspiration characteristics value according to the fever temperature, the perspiration characteristics value according to the fever time, the degree of healing according to the examinee's time, and the difference in perspiration amount per individual. According to the diagnostic device using the skin perspiration reaction, characterized in that to provide data such as the percentage of sweat per body part of the patient in a relative value rather than an absolute value.
  18. 제12항에 있어서, The method of claim 12,
    상기 제어부(900)은 피검사자의 전체 발열 면적을 다수의 소 면적 모듈로 구분하고 상기 각 모듈 하단에 장착한 다수의 센서 및 카메라를 이용하여 온도 분포를 측정한 다음 국소 피부 표면 온도가 설정치 이상으로 높아지는 것을 방지하는, 인체 발한 반응을 이용한 진단 장치.The control unit 900 divides the total heat generating area of the examinee into a plurality of small area modules, measures a temperature distribution using a plurality of sensors and cameras mounted at the bottom of each module, and then increases the local skin surface temperature above a set value. Preventing the diagnosis device using the human body perspiration reaction.
  19. 제12항 내지 제18항 중 어느 하나의 항에 있어서,The method according to any one of claims 12 to 18,
    상기 소프트웨어(700)는 피검사자의 발한 위치, 발한 양 및 발한 분포 등의 발한 특성값을 3차원 표면에 대해 얻은 다음, 이를 2차원 노출 표면적에 대한 평균 발한 특성값으로 보정한 후 발한 위치, 발한 양 및 발한 분포 등의 발한 특성값을 2차원 또는 3차원의 인체 모형 더미가 표현되어 있는 상기 디스플레이부(800)에 표시하는, 인체 발한 반응을 이용한 진단 장치.The software 700 obtains the sweating characteristic values such as the sweating position, the sweating amount, and the sweating distribution of the examinee with respect to the three-dimensional surface, and then corrects the average sweating characteristic value with respect to the two-dimensional exposed surface area, and then checks the sweating position and sweating amount. And a perspiration characteristic value, such as perspiration distribution, on the display unit 800 in which a two-dimensional or three-dimensional dummy model is represented.
  20. 제19항에 있어서,The method of claim 19,
    상기 인체 모형 더미는 상기 디스플레이부(800)의 부위별 클릭이나 터치에 의해 회전 및 확대되거나 해당 부위의 상세한 발한 정보를 제공하는, 인체 발한 반응을 이용한 진단 장치.The dummy dummy body is rotated and enlarged by a click or touch for each part of the display unit 800 or provides detailed sweating information of the corresponding part.
PCT/KR2014/007148 2013-08-04 2014-08-01 Diagnostic system and diagnostic device using human sweating response WO2015020367A1 (en)

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KR20130092301A KR101479415B1 (en) 2013-08-04 2013-08-04 Thermoregulatory Sweat Tester, TST
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KR1020140042334A KR20150117071A (en) 2014-04-09 2014-04-09 Thermoregulatory Sweat Tester(TST)

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