WO2015017125A3 - Procédé de traitement du syndrome de barrett et de l'adénocarcinome œsophagien - Google Patents

Procédé de traitement du syndrome de barrett et de l'adénocarcinome œsophagien Download PDF

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Publication number
WO2015017125A3
WO2015017125A3 PCT/US2014/046702 US2014046702W WO2015017125A3 WO 2015017125 A3 WO2015017125 A3 WO 2015017125A3 US 2014046702 W US2014046702 W US 2014046702W WO 2015017125 A3 WO2015017125 A3 WO 2015017125A3
Authority
WO
WIPO (PCT)
Prior art keywords
metaplasia
methods
esophageal adenocarcinoma
barrett
treating barrett
Prior art date
Application number
PCT/US2014/046702
Other languages
English (en)
Other versions
WO2015017125A2 (fr
Inventor
Eric Matthew Gayle Ellsworth
Sydney David Finkelstein
Sara Ann Jackson
Brendan Corcoran
Dennis Morgan SMITH
Original Assignee
Redpath Integrated Pathology Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/954,247 external-priority patent/US10131942B2/en
Application filed by Redpath Integrated Pathology Inc. filed Critical Redpath Integrated Pathology Inc.
Publication of WO2015017125A2 publication Critical patent/WO2015017125A2/fr
Publication of WO2015017125A3 publication Critical patent/WO2015017125A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des procédés de traitement du syndrome de Barrett et de l'adénocarcinome œsophagien et des procédés de détermination d'une charge de mutation en tant que facteur de prévision du risque d'évolution pathologique du syndrome de Barrett en adénocarcinome œsophagien.
PCT/US2014/046702 2013-07-30 2014-07-15 Procédé de traitement du syndrome de barrett et de l'adénocarcinome œsophagien WO2015017125A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/954,247 2013-07-30
US13/954,247 US10131942B2 (en) 2011-12-01 2013-07-30 Methods for treating barrett's metaplasia and esophageal adenocarcinoma

Publications (2)

Publication Number Publication Date
WO2015017125A2 WO2015017125A2 (fr) 2015-02-05
WO2015017125A3 true WO2015017125A3 (fr) 2015-06-04

Family

ID=52432543

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/046702 WO2015017125A2 (fr) 2013-07-30 2014-07-15 Procédé de traitement du syndrome de barrett et de l'adénocarcinome œsophagien

Country Status (1)

Country Link
WO (1) WO2015017125A2 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002088388A1 (fr) * 2001-04-26 2002-11-07 Ruebben Albert Procede et dispositif de quantification de charges de mutation
US20060088874A1 (en) * 2004-10-22 2006-04-27 Promega Corporation Methods and kits for detecting mutations
US20130143222A1 (en) * 2011-12-01 2013-06-06 RedPath Integrated Pathology, Inc Methods for treating barrett's metaplasia and esophageal adenocarcinoma
US20130267426A1 (en) * 2012-04-10 2013-10-10 Katholieke Universiteit Leuven, K.U. Leuven R&D Microsatellite instability markers in detection of cancer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002088388A1 (fr) * 2001-04-26 2002-11-07 Ruebben Albert Procede et dispositif de quantification de charges de mutation
US20060088874A1 (en) * 2004-10-22 2006-04-27 Promega Corporation Methods and kits for detecting mutations
US20130143222A1 (en) * 2011-12-01 2013-06-06 RedPath Integrated Pathology, Inc Methods for treating barrett's metaplasia and esophageal adenocarcinoma
US20130267426A1 (en) * 2012-04-10 2013-10-10 Katholieke Universiteit Leuven, K.U. Leuven R&D Microsatellite instability markers in detection of cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ELLSWORTH, E ET AL.: "Correlation Of The Presence And Extent Of Loss Of Heterozygosity Mutations With Histological Classifications Of Barrett's Esophagus.", BMC GASTROENTEROL., vol. 12, no. 181, 27 December 2012 (2012-12-27) *

Also Published As

Publication number Publication date
WO2015017125A2 (fr) 2015-02-05

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