WO2015003509A1 - Method and system for monitoring depth of external chest compression and defibrillator - Google Patents

Method and system for monitoring depth of external chest compression and defibrillator Download PDF

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Publication number
WO2015003509A1
WO2015003509A1 PCT/CN2014/074069 CN2014074069W WO2015003509A1 WO 2015003509 A1 WO2015003509 A1 WO 2015003509A1 CN 2014074069 W CN2014074069 W CN 2014074069W WO 2015003509 A1 WO2015003509 A1 WO 2015003509A1
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WO
WIPO (PCT)
Prior art keywords
chest
compression
depth
impedance signal
signal
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PCT/CN2014/074069
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French (fr)
Chinese (zh)
Inventor
李传林
王启
李利亚
左鹏飞
岑建
Original Assignee
深圳迈瑞生物医疗电子股份有限公司
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Publication of WO2015003509A1 publication Critical patent/WO2015003509A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/0809Detecting, measuring or recording devices for evaluating the respiratory organs by impedance pneumography
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271Specific aspects of physiological measurement analysis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H31/00Artificial respiration or heart stimulation, e.g. heart massage
    • A61H31/004Heart stimulation
    • A61H31/005Heart stimulation with feedback for the user
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39Heart defibrillators
    • A61N1/3904External heart defibrillators [EHD]
    • A61N1/39044External heart defibrillators [EHD] in combination with cardiopulmonary resuscitation [CPR] therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/38Applying electric currents by contact electrodes alternating or intermittent currents for producing shock effects
    • A61N1/39Heart defibrillators
    • A61N1/3925Monitoring; Protecting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50Control means thereof
    • A61H2201/5058Sensors or detectors
    • A61H2201/5061Force sensors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H2201/00Characteristics of apparatus not provided for in the preceding codes
    • A61H2201/50Control means thereof
    • A61H2201/5058Sensors or detectors
    • A61H2201/5084Acceleration sensors

Definitions

  • the invention belongs to the field of medical devices and relates to cardiopulmonary resuscitation (Cariopulmonary Resuscitation, CPR) A method of monitoring the depth of chest compressions, a monitoring system, and a defibrillator including the monitoring system.
  • CPR cardiopulmonary resuscitation
  • Cardiopulmonary resuscitation is a key rescue measure for emergency patients with cardiac arrest.
  • the basic life support procedures for adults, children, and babies recommended in the 2010 American Heart Association Cardiopulmonary Resuscitation and Cardiovascular First Aid Guide are CAB (chest).
  • External compression - open airway - artificial respiration which emphasizes the important role of chest compressions in improving patient survival.
  • the CPR pressing parameters mainly include the magnitude of the pressing, the frequency, and the interval between pressing and the like. Obtaining these parameters and monitoring them in real time to the rescuer can guide the rescuer to complete the CPR operation correctly and with high quality.
  • the existing CPR parameter monitoring techniques and their disadvantages are as follows:
  • An acceleration sensor is used to measure the compression depth.
  • external acceleration interference such as CPR during patient transfer
  • the road surface undulation will superimpose other motion acceleration disturbances.
  • the measured value of the acceleration sensor cannot reflect the actual compression acceleration, so the compression depth cannot be accurately measured.
  • An acceleration sensor is used to measure the depth of the press, and a force sensor is used to measure the magnitude of the pressing pressure.
  • the acceleration sensor signal is used to calculate the compression depth, and the correlation between the pressure magnitude and the compression depth is established.
  • the actual compression depth is calculated using the magnitude of the pressure and its dependence on the depth of compression while the patient is in motion. This method adds a set of force sensors and their detection circuits, which increases the system complexity.
  • a method for monitoring the depth of chest compression comprising:
  • the compression depth of the chest compression measurement process is calculated using the real-time chest impedance signal and the determined correlation.
  • a monitoring system for chest compression depth comprising:
  • a signal acquisition unit configured to obtain a reference acceleration signal and a reference chest impedance signal of the chest compression calibration process, and a real-time chest impedance signal for acquiring the chest compression measurement process
  • a correlation determining unit configured to calculate a reference pressing depth using the reference acceleration signal, and determine a correlation between the reference chest impedance signal and the reference pressing depth
  • a defibrillator comprising a defibrillator body, and an acceleration sensor electrically coupled to the defibrillator body and at least two electrode sheets.
  • the acceleration sensor is configured to collect a reference acceleration signal of a chest compression calibration process
  • the electrode piece is used to collect a reference chest impedance signal of the chest compression calibration process and a real-time chest impedance signal of the chest compression measurement process.
  • the defibrillator body also includes the above-described monitoring system for chest compression depth.
  • the monitoring system and the defibrillator including the monitoring system, since the signal acquisition process can be completed by the acceleration sensor and the electrode piece provided by the defibrillator, no additional hardware configuration or modification is required. System complexity is significantly reduced. Further, since the thoracic impedance signal is not easily affected by external motion interference, after the chest compression calibration process determines the correlation between the thoracic impedance and the compression depth, the thoracic impedance signal is used in the measurement of the chest compression and its correlation with the compression depth.
  • the monitoring of the depth of compression can basically avoid the interference of external motion, and can more accurately monitor the effect of CPR implementation, thereby more effectively controlling the defibrillation intensity, thereby obtaining more accurate monitoring results and providing better guidance effects.
  • FIG. 1 is a flow chart of a method for monitoring chest compression depth according to an embodiment
  • FIG. 2 is a flow chart of a method for monitoring a chest-external compression depth according to another embodiment
  • FIG. 3 is a flow chart of a method for monitoring a chest-external compression depth according to an embodiment
  • FIG. 4 is a schematic view of a monitoring system for chest compression depth according to an embodiment
  • FIG. 5 is a schematic diagram of a monitoring system for a chest-external compression depth according to another embodiment
  • FIG. 6 is an exemplary block diagram of a defibrillator of an embodiment
  • Fig. 7 is a schematic diagram showing an acceleration sensor and an electrode sheet of a defibrillator applied to an object to be monitored according to an embodiment.
  • the present invention provides a correlation based on chest impedance and compression depth to monitor CPR compression parameters
  • the system and method (hereinafter referred to as monitoring system and monitoring method), and provides a defibrillator with the above monitoring performance.
  • 'correlation' refers to the correlation (or proportional relationship) of both the chest impedance signal (the measured value or the change value) and the compression depth calculated by the acceleration.
  • the correlation established by the measured value of the thoracic impedance signal and the depth of compression is hereinafter referred to as direct correlation
  • the correlation established by the change value of the thoracic impedance signal and the depth of compression is referred to as indirect correlation.
  • the thoracic impedance signal is not easily interfered by external motion factors. Therefore, as long as the correlation between the compression depth and the chest impedance signal can be accurately determined, the measurement of the compression depth can be performed indirectly by measuring the chest impedance signal.
  • step S11 The reference chest impedance signal and the reference acceleration signal of the chest cavity being pressed during the calibration of the chest compression are obtained respectively.
  • This signal acquisition process typically yields a curve that reflects the reference acceleration and reference chest impedance as a function of time.
  • Correlation analysis is performed on the change value of the reference thoracic impedance signal and the reference compression depth during the chest compression calibration process to determine the indirect correlation between the thoracic impedance and the compression depth (step S12):
  • a double integral operation is performed on the reference acceleration signal obtained during the chest compression calibration process to obtain a reference compression depth.
  • the compression depth calculated according to the acceleration signal can be implemented by a software algorithm, or can be implemented by a hardware circuit.
  • the integral calculation formula corresponding to the pressing speed v(t) and the (reference) pressing displacement S(t) is (a represents the value of the (reference) acceleration signal, v represents (reference) pressing speed, and S represents (reference) pressing Displacement):
  • the change value referred to herein refers to the difference between the measured value of the reference thoracic impedance signal acquired during chest compression and the initial value of the reference thoracic impedance signal acquired before chest compression (ie, measured value - initial value).
  • the initial value of the reference thoracic impedance signal before chest compression is a fixed value
  • the measured value of the reference thoracic impedance signal during a single chest compression is a variable that can be represented by a curve, so
  • the change value of the reference chest impedance signal obtained based on the above calculation method is also a variable in a single compression process.
  • the present invention can obtain the reference acceleration signal and the reference chest impedance signal of the chest compression calibration process according to a specific frequency.
  • the reference chest impedance signal (Z T1 ) at time T1 is obtained , and the change value ⁇ Z1 (Z T1 -Z initial ) of the reference chest impedance signal at the time point is calculated, and the reference compression depth S1 corresponding to the time point T1 is calculated;
  • the ratio of the reference compression depth to the change value of the reference chest impedance signal (S1/ ⁇ Z1) is the K2 value corresponding to the change value of the reference chest impedance signal.
  • the real-time chest impedance signal of the monitored subject during the chest compression measurement process is acquired in the next step S13.
  • ⁇ Z) Calculate the compression depth of the chest compression measurement process.
  • the calculation of the change value of the real-time thoracic impedance signal is the same as the calculation of the change value of the reference thoracic impedance signal in step S12, and thus the compression depth calculated based on the determined correlation is also a variable.
  • the curve of the compression depth can be obtained, which plays a role of real-time monitoring.
  • the pressing frequency and the pressing time interval are further calculated by pressing the peak time of the depth curve.
  • step S22 the correlation value of the reference chest impedance signal and the reference compression depth are directly analyzed during the chest compression calibration process (step S22), so when monitoring the compression depth
  • the measurement of the real-time chest impedance signal is used directly for calculation.
  • the reference acceleration signal and the reference thoracic impedance signal of the chest compression calibration process can be obtained according to the specific frequency according to the monitoring accuracy.
  • the measured value of the reference chest impedance signal at the time point T1 is obtained, and the reference pressing depth S1 corresponding to the time point T1 is calculated; the ratio (S1/Z1) of the reference pressing depth to the measured value of the reference chest impedance signal is the reference chest cavity.
  • the K1 value corresponding to the measured value of the impedance signal can be obtained by taking N values.
  • the determined correlation can be obtained in the following ways: 1.
  • the K1/K2 value is correlated with the thoracic impedance signal (measurement) a smooth curve of change in value or change value; 2. a line of K1/K2 value that varies with the chest impedance signal (measured value or change value); 3. a correspondence between the K1/K2 value and the chest impedance signal (measured value or change value) table.
  • Manner 1 The value of N times is used to obtain N corresponding K1/K2 values.
  • the measured value or change value of the thoracic impedance signal is the abscissa, and the corresponding N points are obtained on the x-y coordinate system corresponding to the K1 value or the K2 value as the ordinate.
  • a smooth curve is used to connect the above N points, that is, a smooth curve reflecting the change of the K1 value or the K2 value corresponding to the measured value or the change value of the chest impedance signal.
  • Manner 2 Take N values for N corresponding K1/K2 values. Taking the measured value or change value of the thoracic impedance signal as the abscissa, corresponding to the K1 value or the K2 value as the ordinate, obtaining the corresponding N points on the xy coordinate system, and establishing the fitting curve of the above N points; fitting The curve is also a smooth curve reflecting the change in the K1 value or the K2 value corresponding to the measured or changed value of the chest impedance signal.
  • Manner 3 Take N values for N corresponding K1/K2 values.
  • the measured value or change value of the thoracic impedance signal is the abscissa, and the corresponding N points are obtained on the x-y coordinate system corresponding to the K1 value or the K2 value as the ordinate.
  • the two adjacent points are connected, that is, a line indicating that the K1 value or the K2 value corresponds to the measured value or the change value of the chest impedance signal.
  • Method 4 Establish a correspondence table between the measured value/variation value of the thoracic impedance signal and the K1 value/K2 value.
  • the above four K1/K2 values are determined only to clarify the technical solution of the present invention, and do not constitute any limitation to the present invention.
  • the curve obtained by the method can better reflect the variation of the K1/K2 value on the one hand, and avoid the thoracic impedance signal (or its variation value) during the calibration of the chest compression on the other hand.
  • the maximum value is smaller than the actual measured value.
  • the monitoring method proposed by the present invention focuses on the one-to-one correspondence between the chest impedance signal and the compression depth which is not affected by the external environment, and further determines the compression depth by acquiring the thoracic impedance signal. Therefore, regardless of the operational transformation of the thoracic impedance signal, such as square, integral, etc., as long as the correlation (or the corresponding relationship) of the two can be established, the accurate monitoring desired by the present invention can be achieved.
  • the "chest external compression calibration process” involved in the above monitoring method may be a process in which the rescuer performs the first complete CPR chest compression operation on the monitored object, and may be preset, and the rescuer implements the monitored object.
  • the Nth CPR chest compression operation may be a preset N-th CPR chest compression operation performed by the rescuer on the subject to be monitored.
  • the present invention preferably uses the first chest compression operation as its calibration process.
  • the "thoracic compression measurement process” involved in the above monitoring method may be a chest compression operation performed after or at the same time determining the correlation between the chest impedance change and the compression depth, that is, may be a subsequent operation or a parallel operation.
  • the output monitoring value discards the compression depth generated by the first chest compression; if the measurement process is set to parallel operation, the compression obtained by the calibration process is obtained. Depth is taken as the first measurement. It should be noted that when the K1/K2 value is obtained by the second method described above, if the measurement process is set to operate in parallel, it is necessary to further recalculate the compression depth of the calibration process using the established correlation.
  • the monitoring method of the above embodiment uses the thoracic impedance signal to complete the monitoring after determining the correlation between the thoracic impedance and the compression depth. Since the thoracic impedance signal is not interfered by external motion, the above monitoring method can well solve the prior art acceleration sensor. Defects in the depth of compression cannot be accurately measured in a moving environment.
  • the monitoring method of the present embodiment further includes acquiring a real-time acceleration signal of the chest compression measurement process (step S34) and determining the chest compression measurement process.
  • the external environment step S35).
  • the real-time acceleration signal acquired during the chest compression measurement process is also the change associated with the chest impedance signal.
  • determining an external environment of the chest compression measurement process includes determining whether the external environment of the process is a motion environment, that is, whether there is interference of external motion acceleration. If the obtained real-time acceleration signal is non-zero and the real-time chest impedance signal changes at the same time, it is judged that the external environment at this time is a static environment; if the acquired real-time acceleration signal is non-zero, and the real-time chest impedance signal is simultaneously If it remains unchanged, it is judged that the external environment at this time is a sports environment. This is because the external motion acceleration can only affect the measured value of the real-time acceleration signal without causing a change in the real-time chest impedance. This step does not involve new sensor components, which is advantageous for cost control of the monitoring process of the present invention.
  • the signal basis for the subsequent calculation of the depth of compression during the measurement of the chest compression is determined.
  • the acquired real-time acceleration signal has low noise, which can reflect the acceleration information actually implemented on the monitored object, and can also determine the compression depth through the real-time acceleration signal.
  • the object to be monitored is in a sports environment, such as an ambulance transport and other pre-hospital emergency situations, the motion acceleration caused by the motion of the road surface is disturbed by the actual acceleration signal, so that the real-time acceleration signal is noisy and cannot be directly applied to the compression depth. Accurate monitoring.
  • the chest compression depth is directly calculated using the acquired real-time acceleration signal (S36a). As described above, the real-time acceleration signal is double-integrated to obtain the compression depth, and the pressing frequency and the pressing time interval are further calculated by pressing the peak time of the depth curve.
  • the compression depth and other compression parameters are calculated using the real-time chest impedance signal and the correlation determined in step S32. Since the correlation between the measured value or the change value of the thoracic impedance signal and the compression depth has been established, when the real-time thoracic impedance signal is acquired, the real-time compression depth of the chest compression measurement process can be calculated by the correlation determined above. Then, other parameter values such as the pressing frequency are also calculated by pressing the peak time of the depth curve.
  • the monitoring method described above may further include a monitored object determining step.
  • the thoracic impedance reflects the physiological parameter values of a particular monitored object, and must have individual differences, and thus have different correlations with respect to the same acceleration signal.
  • the monitoring method further determines whether the monitored object has changed. If a change occurs, the correlation between chest impedance and compression depth needs to be redefined. Preferably, the subject being monitored is judged once a single chest compression is completed.
  • the present invention does not impose any restrictions on how to determine whether a monitored object has changed.
  • the present invention can compare the chest impedance signal at the beginning of each chest compression without adding any sensors or signal acquisition units.
  • the thoracic impedance signal of the same monitored subject at the beginning of chest compression should remain unchanged; if the change exceeds a certain range (for example, 5%), the thoracic impedance signals of different monitored subjects are considered to be acquired.
  • the present invention may require input of the monitored object ID, acquisition of fingerprint information of a specific monitored object, time at which a measurement signal can be detected or acquired, and the like before the first chest compression is performed.
  • the present invention is capable of acquiring parameter values reflecting the unique attributes of the monitored object, it is possible to determine whether the monitored object changes based on a simple comparison of the parameter values.
  • the above monitoring method further considers the external environment of the chest compression calibration process.
  • the initial environmental environment type of the chest compression calibration process is first determined.
  • the role of determining the starting external environment is to perform a correlation analysis (ie, re-determine the K1/K2 of the chest compression calibration process) if the external environment of the subsequent measurement process changes from the initial motion environment to the stationary environment. Value) and update the results of the correlation analysis.
  • the correlation obtained in the static environment can more accurately reflect the relationship between the two variables of the chest impedance and the compression depth because there is no external disturbance. Therefore, the present invention preferably uses the correlation analysis result obtained in a static environment.
  • the monitoring system includes a signal acquisition unit 11, a correlation determination unit 12, and a compression depth calculation unit 13.
  • the signal acquisition unit 11 is configured to acquire a reference acceleration signal and a reference chest impedance signal of the chest compression calibration process, and a real-time chest impedance signal for acquiring the chest compression measurement process.
  • the above signals acquired by the signal acquisition unit 11 are all variables that vary with time.
  • the reference acceleration signal and the reference thoracic impedance signal are used for correlation analysis of chest impedance and compression depth
  • the real-time chest impedance signal is the signal basis for calculating the compression depth.
  • the correlation determination unit 12 is for determining the correlation between the chest impedance and the compression depth.
  • the determining operation includes calculating a change value of the reference chest impedance signal, calculating a reference compression depth using the reference acceleration signal, and determining a proportional relationship (ie, a K2 value) of the reference compression depth to a change value of the reference chest impedance signal.
  • a K2 value a proportional relationship of the reference compression depth to a change value of the reference chest impedance signal.
  • the pressing depth calculation unit 13 is for pressing the calculation operation of the depth. After determining the K2 value, the calculation unit can determine the compression depth by calculating the change value of the real-time chest impedance signal.
  • the correlation determining unit itself can complete the calculation of the change value of the reference chest impedance signal and the reference pressing depth
  • the change value of the chest impedance signal can also be performed only by the pressing depth calculating unit in the monitoring system.
  • the calculation operation of the compression depth (including the calibration process and the correlation calculation of the measurement process), the correlation determination unit acquires the required calculation result by interaction with the compression depth calculation unit.
  • the correlation determining unit can also directly establish the correlation between the reference chest impedance signal and the reference pressing depth; the pressing depth calculating unit thus directly calculates the pressing depth using the obtained real-time chest impedance signal (as in the second embodiment).
  • the correlation determining unit may have the operability to determine the above direct correlation or indirect correlation.
  • the monitoring system at this time may further include a correlation mode selection unit for selecting whether to use the chest impedance signal or the change value as a signal basis in the correlation determination process, and thus the calculation operation of the compression depth calculation unit.
  • the monitoring system of another embodiment includes a signal acquisition unit 11, an external environment determination unit 14, a correlation determination unit 12, and a compression depth calculation unit 13.
  • the example lower signal acquisition unit 11 is further configured to acquire a real-time acceleration signal of the chest compression measurement process
  • the external environment determination unit 14 determines the external environment of the chest compression measurement process according to the acquired real-time acceleration signal and the real-time chest impedance signal. Specifically, when the real-time acceleration signal is non-zero and the real-time chest impedance signal changes, it is determined that the external environment of the chest compression measurement process is a stationary environment. When the real-time acceleration signal is non-zero and the real-time chest impedance signal remains unchanged, the external environment of the chest compression measurement process is determined to be a sports environment; the real-time acceleration acquired at this time is not generated by chest compression.
  • the monitoring system may further include a monitored object determining unit.
  • the monitored object determining unit is configured to determine whether the monitored object has changed.
  • the monitored object determination unit may employ the above-described signal acquisition unit to determine whether the monitored object has changed by comparing the chest impedance signal before the start of the chest compression.
  • the correlation determining unit is further configured to re-determine the correlation between the chest impedance and the compression depth when the monitored object changes.
  • FIG. 6 further illustrates a defibrillator comprising an embodiment of the above described monitoring system.
  • the defibrillator 10 includes a defibrillator body 101, and an acceleration sensor 102 and at least two electrode sheets 103, 104 electrically connected to the defibrillator body 101.
  • the defibrillator body 101 further includes the above-described monitoring system for the chest compression depth.
  • the monitoring system of the chest compression depth includes the signal acquisition unit 11, the correlation determination unit 12, and the compression depth calculation unit 13.
  • the signal acquisition unit 11 of the chest compression depth monitoring system is connected to the acceleration sensor 102 and the electrode sheets 103, 104.
  • the monitoring system may further include an external environment determining unit not illustrated. The monitoring system has been described in detail in Figure 4-5 and will not be repeated here.
  • the acceleration sensor 102 and the electrode sheets 103, 104 are electrically connected to the defibrillator body 101, so that the auxiliary measurement of the pressing parameter can be realized by the defibrillator.
  • the acceleration sensor 102 is used to obtain a reference acceleration signal of the chest compression calibration process.
  • the acceleration sensor 102 can also be used to acquire a real-time acceleration signal of the chest compression measurement process.
  • the electrode sheets 103, 104 are used to obtain a reference chest impedance signal of the chest compression calibration process and a real-time chest impedance signal of the chest compression measurement process.
  • the acceleration sensor and the electrode sheets (for example, two) applied to the object to be monitored during the monitoring are as shown in FIG.
  • the acceleration sensor is disposed directly above the chest of the object to be monitored, and the rescuer applies pressure to the object to be monitored through the acceleration sensor 102.
  • the two electrode sheets 103, 104 are respectively disposed outside the chest of the object to be monitored, and the impedance measurement circuit of the defibrillator body 101 itself is used to measure the chest impedance.
  • the measurement of the thoracic impedance signal does not require a separate set of sensors and detection circuits, and the system complexity can be significantly reduced compared to the prior art using the acceleration sensor and the force sensor.
  • the defibrillator main body 101 further includes a defibrillation intensity adjusting unit electrically connected to the pressing depth calculating unit 13. Chest compression is usually performed before defibrillation in vitro, and the CPR effect can be reflected to some extent by monitoring the compression depth. In the initial defibrillation, the amount of defibrillation current can be appropriately adjusted according to the specific value and/or the trend of the compression depth, and the defibrillation effect is ensured while the damage to the myocardium is minimized.
  • the defibrillator 10 of the present invention can provide a more reliable guiding effect for the regulation of defibrillation intensity by improving the accuracy of the compression depth monitoring.
  • the present invention can also monitor parameters such as artificial respiratory ventilation. Feedback of these compression parameters to the rescuer in a timely manner can guide the rescuer to implement high quality CPR first aid measures.
  • the correlation between the chest impedance and the compression depth is described above, since the compression depth is calculated from the acceleration signal, the correlation between the chest impedance and the compression depth may also indirectly reflect the correlation between the chest impedance and the acceleration signal.
  • the correlation determining step or correlation determining unit of the present invention is not limited to determining only the correlation between the pressing depth and the chest impedance, and the pressing parameter monitoring based on the correlation of the chest impedance and the acceleration signal is also included in the scope of the present invention.

Abstract

Disclosed are a method and a system for monitoring the depth of external chest compression. The monitoring system comprises: a signal acquisition unit (11) for acquiring a reference acceleration signal and a reference thoracic cavity impedance signal when calibrating the external chest compression and for acquiring a real-time thoracic cavity impedance signal when measuring the external chest compression; a correlation determination unit (12) for calculating a reference compression depth using the reference acceleration signal and determining the correlation between the reference thoracic cavity impedance signal and the reference compression depth; and a compression depth calculation unit (13) for calculating a compression depth during measuring external chest compression using the real-time thoracic cavity impedance signal and the determined correlation. Since a thoracic cavity impedance signal can not easily be interfered with by an outside movement, monitoring a compression depth by using the thoracic cavity impedance and the correlation thereof with a compression depth can effectively prevent the interference of external acceleration and help to obtain a more accurate monitoring result. When measuring a thoracic cavity impedance signal, there is no need to excessively adjust the hardware and software of the monitoring system, thus reducing the system complexity.

Description

胸外按压深度的监测方法、监测系统和除颤仪Monitoring method for chest compression depth, monitoring system and defibrillator
【技术领域】[Technical Field]
本发明属于医疗器械领域,并涉及一种心肺复苏( Cardiopulmonary Resuscitation,CPR )胸外按压深度的监测方法、监测系统和 包括该监测系统的 除颤仪。  The invention belongs to the field of medical devices and relates to cardiopulmonary resuscitation (Cariopulmonary Resuscitation, CPR) A method of monitoring the depth of chest compressions, a monitoring system, and a defibrillator including the monitoring system.
【背景技术】【Background technique】
心肺复苏(CPR)是针对心脏骤停的急症患者所采取的关键抢救措施,《2010美国心脏协会心肺复苏及心血管急救指南》中推荐的成人、儿童和婴儿的基础生命支持程序为C-A-B(胸外按压-开放气道-人工呼吸),这更加强调了胸外按压对提高患者存活率的重要作用。Cardiopulmonary resuscitation (CPR) is a key rescue measure for emergency patients with cardiac arrest. The basic life support procedures for adults, children, and babies recommended in the 2010 American Heart Association Cardiopulmonary Resuscitation and Cardiovascular First Aid Guide are CAB (chest). External compression - open airway - artificial respiration), which emphasizes the important role of chest compressions in improving patient survival.
CPR按压参数主要包括按压的幅度、频率和按压的间隔时间等。获取监测这些参数并实时反馈给施救者,可指导施救者正确、高质量的完成CPR操作。现有的CPR参数监测技术及其缺点如下:The CPR pressing parameters mainly include the magnitude of the pressing, the frequency, and the interval between pressing and the like. Obtaining these parameters and monitoring them in real time to the rescuer can guide the rescuer to complete the CPR operation correctly and with high quality. The existing CPR parameter monitoring techniques and their disadvantages are as follows:
采用一个加速度传感器来测量按压深度。在有外部加速度干扰的情况下,如在病人转运过程中实施CPR,路面起伏不平会叠加其它运动加速度干扰,此时加速度传感器的测量值无法反应实际按压的加速度,因此无法准确测量按压深度。An acceleration sensor is used to measure the compression depth. In the case of external acceleration interference, such as CPR during patient transfer, the road surface undulation will superimpose other motion acceleration disturbances. At this time, the measured value of the acceleration sensor cannot reflect the actual compression acceleration, so the compression depth cannot be accurately measured.
采用一个加速度传感器来测量按压的深度,同时用一个力传感器测出按压压力的大小。在患者处于静态时,用加速度传感器信号计算按压深度,并建立压力大小与按压深度的相关性。在患者处于运动的情况下,利用压力大小及其与按压深度的相关性来计算实际的按压深度。这种方法多出了一套力传感器及其检测电路,增加了系统复杂度。An acceleration sensor is used to measure the depth of the press, and a force sensor is used to measure the magnitude of the pressing pressure. When the patient is in a static state, the acceleration sensor signal is used to calculate the compression depth, and the correlation between the pressure magnitude and the compression depth is established. The actual compression depth is calculated using the magnitude of the pressure and its dependence on the depth of compression while the patient is in motion. This method adds a set of force sensors and their detection circuits, which increases the system complexity.
【发明内容】[Summary of the Invention]
基于此,有必要提供一种系统复杂度低且能准确测量按压深度的胸外按压深度的监测方法、监测系统及包括该监测系统的除颤仪。Based on this, it is necessary to provide a monitoring method, a monitoring system, and a defibrillator including the monitoring system, which have low system complexity and can accurately measure the depth of compression.
一种胸外按压深度的监测方法,包括:A method for monitoring the depth of chest compression, comprising:
获取胸外按压校准过程的参考加速度信号和参考胸腔阻抗信号;Obtaining a reference acceleration signal and a reference chest impedance signal of the chest compression calibration process;
使用所述参考加速度信号计算参考按压深度,并确定所述参考胸腔阻抗信号与所述参考按压深度的相关性;Calculating a reference compression depth using the reference acceleration signal, and determining a correlation of the reference chest impedance signal with the reference compression depth;
获取胸外按压测量过程的实时胸腔阻抗信号;以及Obtaining a real-time chest impedance signal from the chest compression measurement process;
使用所述实时胸腔阻抗信号和确定的所述相关性计算胸外按压测量过程的按压深度。The compression depth of the chest compression measurement process is calculated using the real-time chest impedance signal and the determined correlation.
一种胸外按压深度的监测系统,包括:A monitoring system for chest compression depth, comprising:
信号获取单元,用于获取胸外按压校准过程的参考加速度信号和参考胸腔阻抗信号,以及用于获取胸外按压测量过程的实时胸腔阻抗信号;a signal acquisition unit, configured to obtain a reference acceleration signal and a reference chest impedance signal of the chest compression calibration process, and a real-time chest impedance signal for acquiring the chest compression measurement process;
相关性确定单元,用于使用所述参考加速度信号计算参考按压深度,并确定所述参考胸腔阻抗信号与所述参考按压深度的相关性;a correlation determining unit, configured to calculate a reference pressing depth using the reference acceleration signal, and determine a correlation between the reference chest impedance signal and the reference pressing depth;
按压深度计算单元,用于使用所述实时胸腔阻抗信号和确定的所述相关性计算胸外按压测量过程的按压深度。Pressing a depth calculation unit for calculating a compression depth of the chest compression measurement process using the real-time chest impedance signal and the determined correlation.
一种除颤仪,包括除颤仪主体、以及与所述除颤仪主体电连接的加速度传感器和至少两个电极片。所述加速度传感器用于采集胸外按压校准过程的参考加速度信号,所述电极片用于采集胸外按压校准过程的参考胸腔阻抗信号和胸外按压测量过程的实时胸腔阻抗信号。所述除颤仪主体还包括上述胸外按压深度的监测系统。A defibrillator comprising a defibrillator body, and an acceleration sensor electrically coupled to the defibrillator body and at least two electrode sheets. The acceleration sensor is configured to collect a reference acceleration signal of a chest compression calibration process, and the electrode piece is used to collect a reference chest impedance signal of the chest compression calibration process and a real-time chest impedance signal of the chest compression measurement process. The defibrillator body also includes the above-described monitoring system for chest compression depth.
在上述胸外按压深度的监测方法、监测系统及包括该监测系统的除颤仪中,由于信号采集过程可由除颤仪自带的加速度传感器和电极片完成,无需进行额外的硬件配置或改造,系统复杂度明显降低。进一步地,由于胸腔阻抗信号不易受外界运动干扰的影响,因此在胸外按压校准过程确定胸腔阻抗与按压深度的相关性后,胸外按压测量过程中利用胸腔阻抗信号及其与按压深度的相关性进行按压深度的监测可以基本避免外界运动的干扰,可以更准确地监测CPR实施效果,从而更为有效的控制除颤强度,从而获得更准确的监测结果和提供更好的指导效果。In the above monitoring method of the chest compression depth, the monitoring system and the defibrillator including the monitoring system, since the signal acquisition process can be completed by the acceleration sensor and the electrode piece provided by the defibrillator, no additional hardware configuration or modification is required. System complexity is significantly reduced. Further, since the thoracic impedance signal is not easily affected by external motion interference, after the chest compression calibration process determines the correlation between the thoracic impedance and the compression depth, the thoracic impedance signal is used in the measurement of the chest compression and its correlation with the compression depth. The monitoring of the depth of compression can basically avoid the interference of external motion, and can more accurately monitor the effect of CPR implementation, thereby more effectively controlling the defibrillation intensity, thereby obtaining more accurate monitoring results and providing better guidance effects.
【附图说明】[Description of the Drawings]
为了更清楚地说明本发明实施例,下面将对实施例中所需要使用的附图作简单地介绍,显而易见地,下面描述中的附图仅仅是本发明的一些实施例,对于本领域普通技术人员来讲,在不付出创造性劳动的前提下,还可以根据这些附图获得其他的附图。In order to more clearly illustrate the embodiments of the present invention, the drawings, which are used in the embodiments, will be briefly described below. It is obvious that the drawings in the following description are only some embodiments of the present invention. For the personnel, other drawings can be obtained based on these drawings without paying creative labor.
图1为一实施方式的胸外按压深度的监测方法的流程图;1 is a flow chart of a method for monitoring chest compression depth according to an embodiment;
图2为另一实施方式的中胸外按压深度的监测方法的流程图;2 is a flow chart of a method for monitoring a chest-external compression depth according to another embodiment;
图3为一实施方式的中胸外按压深度的监测方法的流程图;3 is a flow chart of a method for monitoring a chest-external compression depth according to an embodiment;
图4为一实施方式的胸外按压深度的监测系统的示意图;4 is a schematic view of a monitoring system for chest compression depth according to an embodiment;
图5为另一实施方式的中胸外按压深度的监测系统的示意图;FIG. 5 is a schematic diagram of a monitoring system for a chest-external compression depth according to another embodiment; FIG.
图6为一实施方式的除颤仪的示例性框图;以及6 is an exemplary block diagram of a defibrillator of an embodiment;
图7为一实施方式的将除颤仪的加速度传感器和电极片实施于被监测对象的示意图。Fig. 7 is a schematic diagram showing an acceleration sensor and an electrode sheet of a defibrillator applied to an object to be monitored according to an embodiment.
【具体实施方式】 【detailed description】
以下说明提供了用于完全理解各个实施例以及用于本领域的技术人员实施的特定细节。然而,本领域的技术人员应该理解,无需这样的细节亦可实践本发明。在一些实例中,为了避免不必要地混淆对实施例的描述,没有详细示出或描述公知的结构和功能。除非上下文清楚地要求,否则,贯穿本说明书和权利要求,用语 ' 包括 ' 、 ' 包含 ' 等应以包含性的意义来解释而不是排他性或穷尽性的意义,即,其含义为 ' 包括,但不限于 ' 。在本详细描述部分中,使用单数或复数的用语也分别包括复数或单数。 The following description provides specific details for the complete understanding of the various embodiments and the embodiments of the invention. However, it will be understood by those skilled in the art that the present invention may be practiced without such detail. In some instances, well known structures and functions are not shown or described in detail in order to avoid obscuring the description of the embodiments. Unless the context clearly requires, the terms throughout the specification and claims ' Include ' , ' include ' etc . shall be interpreted in an inclusive sense rather than an exclusive or exhaustive meaning, ie, meaning 'including, but not limited to' . In the detailed description, the terms singular or plural refer to the plural or singular.
本发明提供了一种基于胸腔阻抗和按压深度的相关性来监测 CPR 按压参数 的系统及方法(以下简称监测系统和监测方法),并提供了一种具有上述监测性能的除颤仪。这里所说的'相关性'指胸腔阻抗信号(其测量值或变化值)和通过加速度计算得到的按压深度这两者的相关性(或比例关系)。为便于描述,以下将通过胸腔阻抗信号的测量值和按压深度建立的相关性称为直接相关性,将通过胸腔阻抗信号的变化值和按压深度建立的相关性称为间接相关性。胸腔阻抗信号不易受外界运动因素干扰,因此只要能准确确定按压深度和胸腔阻抗信号的相关性,就可通过测量胸腔阻抗信号间接完成按压深度的测量。 The present invention provides a correlation based on chest impedance and compression depth to monitor CPR compression parameters The system and method (hereinafter referred to as monitoring system and monitoring method), and provides a defibrillator with the above monitoring performance. As used herein, 'correlation' refers to the correlation (or proportional relationship) of both the chest impedance signal (the measured value or the change value) and the compression depth calculated by the acceleration. For convenience of description, the correlation established by the measured value of the thoracic impedance signal and the depth of compression is hereinafter referred to as direct correlation, and the correlation established by the change value of the thoracic impedance signal and the depth of compression is referred to as indirect correlation. The thoracic impedance signal is not easily interfered by external motion factors. Therefore, as long as the correlation between the compression depth and the chest impedance signal can be accurately determined, the measurement of the compression depth can be performed indirectly by measuring the chest impedance signal.
图 1 为一实施方式的监测方法的流程图。在对被监测对象实施胸外按压后,首先在步骤 S11 中分别获取被监测对象在胸外按压校准过程中的参考胸腔阻抗信号和胸腔被按压的参考加速度信号。该信号获取过程通常得到反映参考加速度和参考胸腔阻抗随时间变化的曲线。 1 is a flow chart of a monitoring method of an embodiment. After performing chest compression on the monitored object, first in step S11 The reference chest impedance signal and the reference acceleration signal of the chest cavity being pressed during the calibration of the chest compression are obtained respectively. This signal acquisition process typically yields a curve that reflects the reference acceleration and reference chest impedance as a function of time.
随后在胸外按压校准过程中对参考胸腔阻抗信号的变化值和参考按压深度进行相关性分析,确定胸腔阻抗与按压深度的间接相关性(步骤 S12): Correlation analysis is performed on the change value of the reference thoracic impedance signal and the reference compression depth during the chest compression calibration process to determine the indirect correlation between the thoracic impedance and the compression depth (step S12):
(1)对在胸外按压校准过程获取的参考加速度信号进行双重积分运算得到参考按压深度。根据加速信号计算得到按压深度可以通过软件算法实现,也可以采用硬件电路实现。(参考)按压速度v(t)和(参考)按压位移S(t)对应的积分计算公式为(a表示(参考)加速度信号的值,v表示(参考)按压速度,S表示(参考)按压位移):(1) A double integral operation is performed on the reference acceleration signal obtained during the chest compression calibration process to obtain a reference compression depth. The compression depth calculated according to the acceleration signal can be implemented by a software algorithm, or can be implemented by a hardware circuit. (Reference) The integral calculation formula corresponding to the pressing speed v(t) and the (reference) pressing displacement S(t) is (a represents the value of the (reference) acceleration signal, v represents (reference) pressing speed, and S represents (reference) pressing Displacement):
v(t)=∫adt; v(t)=∫adt;
S(t)=∫v(t)dt。 S(t)=∫v(t)dt.
(2)计算胸外按压校准过程中参考胸腔阻抗信号的变化值。这里所说的变化值指的是:胸外按压过程中获取到的参考胸腔阻抗信号的测量值与胸外按压前获取到的参考胸腔阻抗信号的初始值的差值(即,测量值-初始值)。对于特定的被监测对象而言,实施胸外按压前的参考胸腔阻抗信号的初始值为一固定值,单次胸外按压过程中参考胸腔阻抗信号的测量值是可由曲线表示的变量,因此随着胸外按压的进行,基于以上计算方法获得的参考胸腔阻抗信号的变化值在单次按压过程中同样为一变量。(2) Calculate the change value of the reference thoracic impedance signal during the calibration of the chest compression. The change value referred to herein refers to the difference between the measured value of the reference thoracic impedance signal acquired during chest compression and the initial value of the reference thoracic impedance signal acquired before chest compression (ie, measured value - initial value). For a specific monitored subject, the initial value of the reference thoracic impedance signal before chest compression is a fixed value, and the measured value of the reference thoracic impedance signal during a single chest compression is a variable that can be represented by a curve, so With the progress of chest compression, the change value of the reference chest impedance signal obtained based on the above calculation method is also a variable in a single compression process.
(3)确定参考胸腔阻抗信号的变化值与参考按压深度的间接相关性。在一具体实例中,这种间接相关性可近似为一种比例关系或线性关系,即 S=K2 ×△ Z,其中 S 表示按压深度,△ Z 表示胸腔阻抗信号的变化值,K2 表示按压深度与胸腔阻抗信号的变化值的比值。 (3) Determine the indirect correlation between the change value of the reference thoracic impedance signal and the reference compression depth. In a specific example, this indirect correlation can be approximated as a proportional relationship or a linear relationship, ie, S = K2 × Δ Z, where S Indicates the compression depth, Δ Z represents the change value of the thoracic impedance signal, and K2 represents the ratio of the compression depth to the change value of the thoracic impedance signal.
胸外按压校准过程中,根据监测精度的需要,本发明可按照特定频率获取胸外按压校准过程的参考加速度信号和参考胸腔阻抗信号。例如获取时间点T1的参考胸腔阻抗信号 ( ZT1 ), 计算该时间点处参考胸腔阻抗信号的变化值△ Z1 ( ZT1-Z 初始 ),同时计算时间点 T1 所对应的参考按压深度 S1;参考按压深度和参考胸腔阻抗信号的变化值的比值( S1/ △ Z1 )即为该参考胸腔阻抗信号的变化值所对应的 K2 值。通过以上计算过程,取值 N 次即可获得 N 个对应的 K2 值。During the chest compression calibration process, according to the need of monitoring accuracy, the present invention can obtain the reference acceleration signal and the reference chest impedance signal of the chest compression calibration process according to a specific frequency. For example, the reference chest impedance signal (Z T1 ) at time T1 is obtained , and the change value Δ Z1 (Z T1 -Z initial ) of the reference chest impedance signal at the time point is calculated, and the reference compression depth S1 corresponding to the time point T1 is calculated; The ratio of the reference compression depth to the change value of the reference chest impedance signal (S1/ΔZ1) is the K2 value corresponding to the change value of the reference chest impedance signal. Through the above calculation process, N corresponding K2 values can be obtained by taking N values.
在下一步骤S13中获取被监测对象在胸外按压测量过程的实时胸腔阻抗信号。The real-time chest impedance signal of the monitored subject during the chest compression measurement process is acquired in the next step S13.
在步骤S14中,使用胸外按压测量过程获取的实时胸腔阻抗信号计算实时胸腔阻抗信号的变化值,根据该变化值找到对应的K2值,然后基于其与按压深度的相关性(S=K2 ×△ Z)计算胸外按压测量过程的按压深度。In step S14, the real-time chest impedance signal obtained by the chest compression measurement process is used to calculate the change value of the real-time chest impedance signal, and the corresponding K2 value is found according to the change value, and then based on the correlation with the compression depth (S=K2). ×△ Z) Calculate the compression depth of the chest compression measurement process.
实时胸腔阻抗信号的变化值的计算与步骤S12中参考胸腔阻抗信号的变化值的计算相同,因此随后根据确定的相关性计算得到的按压深度同样为一变量。具体实施过程中可得到按压深度的变化曲线,起到实时监测的作用。按压频率和按压时间间隔则进一步通过按压深度曲线的峰值时间计算得到。The calculation of the change value of the real-time thoracic impedance signal is the same as the calculation of the change value of the reference thoracic impedance signal in step S12, and thus the compression depth calculated based on the determined correlation is also a variable. In the specific implementation process, the curve of the compression depth can be obtained, which plays a role of real-time monitoring. The pressing frequency and the pressing time interval are further calculated by pressing the peak time of the depth curve.
图2为本发明的另一实施方式中监测方法的流程图。与上述实施方式不同的是,在该实施方式中,在胸外按压校准过程中直接对参考胸腔阻抗信号的测量值和参考按压深度进行相关性分析(步骤S22),因此在监测按压深度时也直接使用实时胸腔阻抗信号的测量值进行计算。同样地,这种直接相关性可近似为一种比例关系或线性关系,即 S=K1 × Z ,其中 S 表示按压深度,Z 表示胸腔阻抗信号的测量值, K1 表示按压深度与胸腔阻抗信号的测量值的比值。2 is a flow chart of a monitoring method in another embodiment of the present invention. Different from the above embodiment, in this embodiment, the correlation value of the reference chest impedance signal and the reference compression depth are directly analyzed during the chest compression calibration process (step S22), so when monitoring the compression depth The measurement of the real-time chest impedance signal is used directly for calculation. Similarly, this direct correlation can be approximated as a proportional or linear relationship, ie S = K1 × Z , where S is the compression depth, Z is the measured value of the chest impedance signal, and K1 is the ratio of the compression depth to the measured value of the chest impedance signal.
胸外按压校准过程中,根据监测精度的需要,可按照特定频率获取胸外按压校准过程的参考加速度信号和参考胸腔阻抗信号。例如获取时间点T1的参考胸腔阻抗信号的测量值,同时计算时间点T1所对应的参考按压深度S1;参考按压深度和参考胸腔阻抗信号的测量值的比值(S1/Z1)即为该参考胸腔阻抗信号的测量值所对应的K1值。通过以上计算过程,取值N次即可获得N个对应的K1值。During the chest compression calibration process, the reference acceleration signal and the reference thoracic impedance signal of the chest compression calibration process can be obtained according to the specific frequency according to the monitoring accuracy. For example, the measured value of the reference chest impedance signal at the time point T1 is obtained, and the reference pressing depth S1 corresponding to the time point T1 is calculated; the ratio (S1/Z1) of the reference pressing depth to the measured value of the reference chest impedance signal is the reference chest cavity. The K1 value corresponding to the measured value of the impedance signal. Through the above calculation process, N corresponding K1 values can be obtained by taking N values.
在确认K1/K2值的过程中,无论采用参考胸腔阻抗信号的测量值还是采用其变化值,都可采用以下几种方式得到确定的相关性:1、K1/K2值随胸腔阻抗信号(测量值或变化值)变化的平滑曲线;2、K1/K2值随胸腔阻抗信号(测量值或变化值)变化的折线;3、K1/K2值与胸腔阻抗信号(测量值或变化值)的对应表。In the process of confirming the K1/K2 value, whether the measured value of the reference thoracic impedance signal or the change value is used, the determined correlation can be obtained in the following ways: 1. The K1/K2 value is correlated with the thoracic impedance signal (measurement) a smooth curve of change in value or change value; 2. a line of K1/K2 value that varies with the chest impedance signal (measured value or change value); 3. a correspondence between the K1/K2 value and the chest impedance signal (measured value or change value) table.
方式一:取值N次获取N个对应的K1/K2值。以胸腔阻抗信号的测量值或变化值为横坐标,对应以K1值或K2值为纵坐标,在x-y坐标系上获得对应的N个点。采用光滑曲线连接以上N个点,即得一条反映K1值或K2值对应随胸腔阻抗信号的测量值或变化值变化的平滑曲线。Manner 1: The value of N times is used to obtain N corresponding K1/K2 values. The measured value or change value of the thoracic impedance signal is the abscissa, and the corresponding N points are obtained on the x-y coordinate system corresponding to the K1 value or the K2 value as the ordinate. A smooth curve is used to connect the above N points, that is, a smooth curve reflecting the change of the K1 value or the K2 value corresponding to the measured value or the change value of the chest impedance signal.
方式二:取值N次获取N个对应的K1/K2值。以胸腔阻抗信号的测量值或变化值为横坐标,对应以K1值或K2值为纵坐标,在x-y坐标系上获得对应的N个点,并建立以上N个点的拟合曲线;拟合曲线同样为反映K1值或K2值对应随胸腔阻抗信号的测量值或变化值变化的平滑曲线。Manner 2: Take N values for N corresponding K1/K2 values. Taking the measured value or change value of the thoracic impedance signal as the abscissa, corresponding to the K1 value or the K2 value as the ordinate, obtaining the corresponding N points on the xy coordinate system, and establishing the fitting curve of the above N points; fitting The curve is also a smooth curve reflecting the change in the K1 value or the K2 value corresponding to the measured or changed value of the chest impedance signal.
方式三:取值N次获取N个对应的K1/K2值。以胸腔阻抗信号的测量值或变化值为横坐标,对应以K1值或K2值为纵坐标,在x-y坐标系上获得对应的N个点。相邻两个点连线,即得一条反映K1值或K2值对应随胸腔阻抗信号的测量值或变化值变化的折线。Manner 3: Take N values for N corresponding K1/K2 values. The measured value or change value of the thoracic impedance signal is the abscissa, and the corresponding N points are obtained on the x-y coordinate system corresponding to the K1 value or the K2 value as the ordinate. The two adjacent points are connected, that is, a line indicating that the K1 value or the K2 value corresponds to the measured value or the change value of the chest impedance signal.
方式四:建立胸腔阻抗信号的测量值/变化值与K1值/K2值的对应表,一具体示例参见下表:
胸腔阻抗信号的测量值 / 变化值 K1 值 /K2 值
[Z1,Z2)/ [ △ Z1, △ Z2) K11/K21
[Z2,Z3)/ [ △ Z2, △ Z3) K12/K22
…… ……
[ZN-1,ZN)/ [ △ ZN-1, △ ZN) K1N-1/K2N-1
Method 4: Establish a correspondence table between the measured value/variation value of the thoracic impedance signal and the K1 value/K2 value. For a specific example, see the following table:
Measurement/change value of thoracic impedance signal K1 value / K2 value
[Z 1 , Z 2 ) / [ △ Z 1 , △ Z 2 ) K1 1 /K2 1
[Z 2 , Z 3 ) / [ △ Z 2 , △ Z 3 ) K1 2 /K2 2
...... ......
[Z N-1 , ZN) / [ △ Z N-1 , △ ZN) K1 N-1 /K2 N-1
以上四种K1/K2值的确定方式仅用于对阐明本发明的技术方案,并不对本发明构成任何限制。优选地,采用以上第二种方式,该方式获得的曲线一方面可更好地反映K1/K2值的变化规律,另一方面可以避免胸外按压校准过程中胸腔阻抗信号(或其变化值)的最大值小于实际测量值的情形。The above four K1/K2 values are determined only to clarify the technical solution of the present invention, and do not constitute any limitation to the present invention. Preferably, in the above second manner, the curve obtained by the method can better reflect the variation of the K1/K2 value on the one hand, and avoid the thoracic impedance signal (or its variation value) during the calibration of the chest compression on the other hand. The maximum value is smaller than the actual measured value.
以上虽然采用K1/K2值这一比例关系表示胸腔阻抗信号(测量值或变化值)与按压深度的相关性,但本领域技术人员也可以理解,还可采用其他模型表征胸腔阻抗信号(或其变化值)与按压深度的相关关系。本发明提出的监测方法的重点在于利用不受外界环境影响的胸腔阻抗信号与按压深度的一一对应关系,通过获取胸腔阻抗信号来进一步确定按压深度。因此无论对胸腔阻抗信号进行何种运算变换,例如平方、积分等等,只要能建立两者的相关性(或称为对应关系),均可实现本发明所希望的准确监测。Although the proportional relationship of the K1/K2 value is used to express the correlation between the chest impedance signal (measured value or change value) and the compression depth, those skilled in the art can also understand that other models can be used to characterize the chest impedance signal (or The relationship between the change value and the depth of compression. The monitoring method proposed by the present invention focuses on the one-to-one correspondence between the chest impedance signal and the compression depth which is not affected by the external environment, and further determines the compression depth by acquiring the thoracic impedance signal. Therefore, regardless of the operational transformation of the thoracic impedance signal, such as square, integral, etc., as long as the correlation (or the corresponding relationship) of the two can be established, the accurate monitoring desired by the present invention can be achieved.
以上监测方法中所涉及的“胸外按压校准过程”可以是施救者对被监测对象实施首次完整的CPR胸外按压操作的过程,可以是预先设定的、施救者对被监测对象实施的第N次CPR胸外按压操作,也可以是预先设定的、施救者对被监测对象实施的前N次CPR胸外按压操作。本发明优选将首次胸外按压操作作为其校准过程。以上监测方法中所涉及的“胸外按压测量过程”可以是在确定胸腔阻抗变化与按压深度的相关性之后或同时执行的胸外按压操作,也即可以是后续操作或并行操作。例如,以首次胸外按压作为校准过程时,若测量过程为后续操作,则输出的监测值舍弃首次胸外按压产生的按压深度;若测量过程设定为并行操作,则将校准过程获得的按压深度作为第一个测量值。应该注意的是,当采用上述第二种方式获得K1/K2值时,若测量过程设定为并行操作,则需要进一步利用建立起来的相关性对校准过程的按压深度进行再次计算。The "chest external compression calibration process" involved in the above monitoring method may be a process in which the rescuer performs the first complete CPR chest compression operation on the monitored object, and may be preset, and the rescuer implements the monitored object. The Nth CPR chest compression operation may be a preset N-th CPR chest compression operation performed by the rescuer on the subject to be monitored. The present invention preferably uses the first chest compression operation as its calibration process. The "thoracic compression measurement process" involved in the above monitoring method may be a chest compression operation performed after or at the same time determining the correlation between the chest impedance change and the compression depth, that is, may be a subsequent operation or a parallel operation. For example, when the first chest compression is used as the calibration process, if the measurement process is a subsequent operation, the output monitoring value discards the compression depth generated by the first chest compression; if the measurement process is set to parallel operation, the compression obtained by the calibration process is obtained. Depth is taken as the first measurement. It should be noted that when the K1/K2 value is obtained by the second method described above, if the measurement process is set to operate in parallel, it is necessary to further recalculate the compression depth of the calibration process using the established correlation.
上述实施方式的监测方法在确定胸腔阻抗和按压深度的相关性后则采用胸腔阻抗信号完成监测,由于胸腔阻抗信号不受外界运动干扰,以上监测方法可很好地解决现有技术中加速度传感器在运动环境下无法准确测量按压深度的缺陷。The monitoring method of the above embodiment uses the thoracic impedance signal to complete the monitoring after determining the correlation between the thoracic impedance and the compression depth. Since the thoracic impedance signal is not interfered by external motion, the above monitoring method can well solve the prior art acceleration sensor. Defects in the depth of compression cannot be accurately measured in a moving environment.
图3为另一实施方式的监测方法的流程图。与上述实施方式不同的是,在计算胸外按压测量过程的按压深度之前,本实施方式的监测方法还包括获取胸外按压测量过程的实时加速度信号(步骤S34)和确定胸外按压测量过程的外界环境(步骤S35)。胸外按压测量过程获取的实时加速度信号同样是与胸腔阻抗信号相关的变化值。3 is a flow chart of a monitoring method of another embodiment. Different from the above embodiment, before the calculation of the compression depth of the chest compression measurement process, the monitoring method of the present embodiment further includes acquiring a real-time acceleration signal of the chest compression measurement process (step S34) and determining the chest compression measurement process. The external environment (step S35). The real-time acceleration signal acquired during the chest compression measurement process is also the change associated with the chest impedance signal.
具体地,确定胸外按压测量过程的外界环境包括判断该过程的外界环境是否为运动环境,即是否存在外界运动加速度的干扰。若获取到的实时加速度信号为非零值、且实时胸腔阻抗信号同时发生变化,则判断此时的外界环境为静止环境;若获取到的实时加速度信号为非零值、且实时胸腔阻抗信号同时保持不变,则判断此时的外界环境为运动环境。这是因为外界的运动加速度仅能影响实时加速度信号的测量值,而不会导致实时胸腔阻抗发生变化。该步骤并未涉及新的传感器部件,有利于本发明监测过程的成本控制。Specifically, determining an external environment of the chest compression measurement process includes determining whether the external environment of the process is a motion environment, that is, whether there is interference of external motion acceleration. If the obtained real-time acceleration signal is non-zero and the real-time chest impedance signal changes at the same time, it is judged that the external environment at this time is a static environment; if the acquired real-time acceleration signal is non-zero, and the real-time chest impedance signal is simultaneously If it remains unchanged, it is judged that the external environment at this time is a sports environment. This is because the external motion acceleration can only affect the measured value of the real-time acceleration signal without causing a change in the real-time chest impedance. This step does not involve new sensor components, which is advantageous for cost control of the monitoring process of the present invention.
通过该步骤确定后续计算胸外按压测量过程中按压深度的信号依据。被监测对象处于静止环境时,获取的实时加速度信号噪声小,可以反映真实实施于被监测对象上的加速度信息,也即可通过实时加速度信号确定按压深度。被监测对象处于运动环境时,例如救护车转运等院前急救场合下,路面颠簸等运动造成运动加速度干扰实际获取到的实时加速度信号,使得实时加速度信号噪音较大,无法直接应用于按压深度的准确监测。Through this step, the signal basis for the subsequent calculation of the depth of compression during the measurement of the chest compression is determined. When the monitored object is in a static environment, the acquired real-time acceleration signal has low noise, which can reflect the acceleration information actually implemented on the monitored object, and can also determine the compression depth through the real-time acceleration signal. When the object to be monitored is in a sports environment, such as an ambulance transport and other pre-hospital emergency situations, the motion acceleration caused by the motion of the road surface is disturbed by the actual acceleration signal, so that the real-time acceleration signal is noisy and cannot be directly applied to the compression depth. Accurate monitoring.
若胸外按压测量过程的外界环境为静止环境,直接利用获取到的实时加速度信号计算胸外按压深度(S36a)。如上所述,对实时加速度信号进行双重积分运算得到按压深度,按压频率和按压时间间隔则进一步通过按压深度曲线的峰值时间计算得到。若胸外按压测量过程的外界环境为运动环境,则利用实时胸腔阻抗信号和步骤S32中确定的相关性计算按压深度和其他按压参数。由于已建立胸腔阻抗信号的测量值或变化值与按压深度的相关性关系,在获取到实时胸腔阻抗信号时,则可通过以上确定的相关性计算该次胸外按压测量过程的实时按压深度,随后同样通过按压深度曲线的峰值时间计算按压频率等其他参数值。If the external environment of the chest compression measurement process is a static environment, the chest compression depth is directly calculated using the acquired real-time acceleration signal (S36a). As described above, the real-time acceleration signal is double-integrated to obtain the compression depth, and the pressing frequency and the pressing time interval are further calculated by pressing the peak time of the depth curve. If the external environment of the chest compression measurement process is a motion environment, the compression depth and other compression parameters are calculated using the real-time chest impedance signal and the correlation determined in step S32. Since the correlation between the measured value or the change value of the thoracic impedance signal and the compression depth has been established, when the real-time thoracic impedance signal is acquired, the real-time compression depth of the chest compression measurement process can be calculated by the correlation determined above. Then, other parameter values such as the pressing frequency are also calculated by pressing the peak time of the depth curve.
在另一实施方式中,上述监测方法可进一步包括被监测对象判断步骤。本领域技术人员应该理解,胸腔阻抗反映的是特定被监测对象的生理参数值,必然具有个体区别性,也因此相对于同一加速度信号具有不同的相关性。在计算得到测量过程的按压深度后,该监测方法进一步判断被监测对象是否发生变化。若发生改变,则需要重新确定胸腔阻抗和按压深度的相关性。优选地,在单次胸外按压完成后进行一次被监测对象判断。In another embodiment, the monitoring method described above may further include a monitored object determining step. It should be understood by those skilled in the art that the thoracic impedance reflects the physiological parameter values of a particular monitored object, and must have individual differences, and thus have different correlations with respect to the same acceleration signal. After calculating the compression depth of the measurement process, the monitoring method further determines whether the monitored object has changed. If a change occurs, the correlation between chest impedance and compression depth needs to be redefined. Preferably, the subject being monitored is judged once a single chest compression is completed.
本发明并不对如何判断被监测对象是否发生变化做出任何限制。在不增加任何传感器或信号获取单元的情况下,本发明可比较每次胸外按压开始时的胸腔阻抗信号。同一被监测对象在胸外按压开始时的胸腔阻抗信号应保持不变;若变化超出一定范围(例如5%),则认为获取到的为不同被监测对象的胸腔阻抗信号。在其他实施方式中,本发明可在实施首次胸外按压前要求输入被监测对象ID、可获取具体被监测对象的指纹信息、可检测或获取到测量信号的时间等。只要本发明能够获取反映被监测对象独特属性的参数值,则可基于参数值的简单比较确定被监测对象是否变化。The present invention does not impose any restrictions on how to determine whether a monitored object has changed. The present invention can compare the chest impedance signal at the beginning of each chest compression without adding any sensors or signal acquisition units. The thoracic impedance signal of the same monitored subject at the beginning of chest compression should remain unchanged; if the change exceeds a certain range (for example, 5%), the thoracic impedance signals of different monitored subjects are considered to be acquired. In other embodiments, the present invention may require input of the monitored object ID, acquisition of fingerprint information of a specific monitored object, time at which a measurement signal can be detected or acquired, and the like before the first chest compression is performed. As long as the present invention is capable of acquiring parameter values reflecting the unique attributes of the monitored object, it is possible to determine whether the monitored object changes based on a simple comparison of the parameter values.
在另一实施方式中,上述监测方法进一步考虑了胸外按压校准过程的外界环境。在建立胸腔阻抗与按压深度的相关性之前,首先确定胸外按压校准过程的起始外界环境类型。确定起始外界环境的作用在于,若后续测量过程的外界环境由初始的运动环境转变为静止环境,则重新在静止环境下进行一次相关性分析(即重新确定胸外按压校准过程的K1/K2值),并更新相关性分析的结果。静止环境下得到的相关性因为无外界干扰,往往能够更为准确地反映胸腔阻抗与按压深度这两个变量间的关系,本发明因此优选采用静止环境下获得的相关性分析结果。In another embodiment, the above monitoring method further considers the external environment of the chest compression calibration process. Before establishing the correlation between chest impedance and compression depth, the initial environmental environment type of the chest compression calibration process is first determined. The role of determining the starting external environment is to perform a correlation analysis (ie, re-determine the K1/K2 of the chest compression calibration process) if the external environment of the subsequent measurement process changes from the initial motion environment to the stationary environment. Value) and update the results of the correlation analysis. The correlation obtained in the static environment can more accurately reflect the relationship between the two variables of the chest impedance and the compression depth because there is no external disturbance. Therefore, the present invention preferably uses the correlation analysis result obtained in a static environment.
如图4所示,监测系统包括信号获取单元11、相关性确定单元12和按压深度计算单元13。信号获取单元11用于获取胸外按压校准过程的参考加速度信号和参考胸腔阻抗信号,以及用于获取胸外按压测量过程的实时胸腔阻抗信号。信号获取单元11获取的上述信号均为随时间变化的变量。其中,参考加速度信号和参考胸腔阻抗信号用于胸腔阻抗和按压深度的相关性分析,实时胸腔阻抗信号则是计算按压深度的信号基础。相关性确定单元12用于确定胸腔阻抗和按压深度的相关性。该确定操作包括计算参考胸腔阻抗信号的变化值,使用参考加速度信号计算参考按压深度,以及确定参考按压深度与参考胸腔阻抗信号的变化值的比例关系(即K2值)。如上所述,监测系统所获得的K2值随胸腔阻抗发生改变。按压深度计算单元13用于按压深度的计算操作。在确定K2值后,该计算单元通过计算实时胸腔阻抗信号的变化值即可确定按压深度。As shown in FIG. 4, the monitoring system includes a signal acquisition unit 11, a correlation determination unit 12, and a compression depth calculation unit 13. The signal acquisition unit 11 is configured to acquire a reference acceleration signal and a reference chest impedance signal of the chest compression calibration process, and a real-time chest impedance signal for acquiring the chest compression measurement process. The above signals acquired by the signal acquisition unit 11 are all variables that vary with time. Among them, the reference acceleration signal and the reference thoracic impedance signal are used for correlation analysis of chest impedance and compression depth, and the real-time chest impedance signal is the signal basis for calculating the compression depth. The correlation determination unit 12 is for determining the correlation between the chest impedance and the compression depth. The determining operation includes calculating a change value of the reference chest impedance signal, calculating a reference compression depth using the reference acceleration signal, and determining a proportional relationship (ie, a K2 value) of the reference compression depth to a change value of the reference chest impedance signal. As mentioned above, the K2 value obtained by the monitoring system changes with the chest impedance. The pressing depth calculation unit 13 is for pressing the calculation operation of the depth. After determining the K2 value, the calculation unit can determine the compression depth by calculating the change value of the real-time chest impedance signal.
虽然在图4的监测系统中,相关性确定单元自身可以完成参考胸腔阻抗信号的变化值和参考按压深度的计算,但监测系统中也可仅由按压深度计算单元执行胸腔阻抗信号的变化值和按压深度的计算操作(包括校准过程和测量过程的相关计算),相关性确定单元通过与按压深度计算单元的交互获取所需计算结果。Although in the monitoring system of FIG. 4, the correlation determining unit itself can complete the calculation of the change value of the reference chest impedance signal and the reference pressing depth, the change value of the chest impedance signal can also be performed only by the pressing depth calculating unit in the monitoring system. The calculation operation of the compression depth (including the calibration process and the correlation calculation of the measurement process), the correlation determination unit acquires the required calculation result by interaction with the compression depth calculation unit.
当然,相关性确定单元也可以直接建立参考胸腔阻抗信号与参考按压深度的相关性;按压深度计算单元因此直接采用获得的实时胸腔阻抗信号计算按压深度(如第二实施方式)。Of course, the correlation determining unit can also directly establish the correlation between the reference chest impedance signal and the reference pressing depth; the pressing depth calculating unit thus directly calculates the pressing depth using the obtained real-time chest impedance signal (as in the second embodiment).
在另一实施方式中,相关性确定单元可兼具确定以上直接相关性或间接相关性的操作性。此时的监测系统可进一步包括相关性模式选择单元,用于选择在相关性确定过程中是以胸腔阻抗信号还是以其变化值作为信号依据,以及因此控制按压深度计算单元的计算操作。In another embodiment, the correlation determining unit may have the operability to determine the above direct correlation or indirect correlation. The monitoring system at this time may further include a correlation mode selection unit for selecting whether to use the chest impedance signal or the change value as a signal basis in the correlation determination process, and thus the calculation operation of the compression depth calculation unit.
如图5所示,另一实施方式的监测系统包括信号获取单元11、外界环境确定单元14、相关性确定单元12和按压深度计算单元13。该示例下信号获取单元11还用于获取胸外按压测量过程的实时加速度信号,外界环境确定单元14则根据获取的实时加速度信号和实时胸腔阻抗信号确定胸外按压测量过程的外界环境。具体地,在实时加速度信号为非零值、且实时胸腔阻抗信号发生变化时,判断胸外按压测量过程的外界环境为静止环境。在实时加速度信号为非零值、且实时胸腔阻抗信号保持不变时,判断胸外按压测量过程的外界环境为运动环境;此时获取的实时加速度并不是由胸外按压产生。As shown in FIG. 5, the monitoring system of another embodiment includes a signal acquisition unit 11, an external environment determination unit 14, a correlation determination unit 12, and a compression depth calculation unit 13. The example lower signal acquisition unit 11 is further configured to acquire a real-time acceleration signal of the chest compression measurement process, and the external environment determination unit 14 determines the external environment of the chest compression measurement process according to the acquired real-time acceleration signal and the real-time chest impedance signal. Specifically, when the real-time acceleration signal is non-zero and the real-time chest impedance signal changes, it is determined that the external environment of the chest compression measurement process is a stationary environment. When the real-time acceleration signal is non-zero and the real-time chest impedance signal remains unchanged, the external environment of the chest compression measurement process is determined to be a sports environment; the real-time acceleration acquired at this time is not generated by chest compression.
在另一实施方式中,监测系统还可包括一被监测对象判断单元。被监测对象判断单元用于判断被监测对象是否发生变化。例如,被监测对象判断单元可采用上述信号获取单元,通过比较胸外按压开始前的胸腔阻抗信号判断被监测对象是否发生变化。相关性确定单元还用于在被监测对象发生变化时,重新确定胸外阻抗和按压深度的相关性。In another embodiment, the monitoring system may further include a monitored object determining unit. The monitored object determining unit is configured to determine whether the monitored object has changed. For example, the monitored object determination unit may employ the above-described signal acquisition unit to determine whether the monitored object has changed by comparing the chest impedance signal before the start of the chest compression. The correlation determining unit is further configured to re-determine the correlation between the chest impedance and the compression depth when the monitored object changes.
图6进一步示出了包括上述监测系统的一实施方式的除颤仪。该除颤仪10包括除颤仪主体101、以及与除颤仪主体101电连接的加速度传感器102和至少两个电极片103、104。另外,除颤仪主体101还包括上述胸外按压深度的监测系统。如上所述,胸外按压深度的监测系统包括信号获取单元11、相关性确定单元12和按压深度计算单元13。胸外按压深度的监测系统的信号获取单元11与加速度传感器102以及电极片103、104连接。另外,监测系统也可进一步包括未图示说明的外界环境判断单元。图4-5中已经对监测系统进行了详细描述,在此不再重复叙述。Figure 6 further illustrates a defibrillator comprising an embodiment of the above described monitoring system. The defibrillator 10 includes a defibrillator body 101, and an acceleration sensor 102 and at least two electrode sheets 103, 104 electrically connected to the defibrillator body 101. In addition, the defibrillator body 101 further includes the above-described monitoring system for the chest compression depth. As described above, the monitoring system of the chest compression depth includes the signal acquisition unit 11, the correlation determination unit 12, and the compression depth calculation unit 13. The signal acquisition unit 11 of the chest compression depth monitoring system is connected to the acceleration sensor 102 and the electrode sheets 103, 104. In addition, the monitoring system may further include an external environment determining unit not illustrated. The monitoring system has been described in detail in Figure 4-5 and will not be repeated here.
加速度传感器102和电极片103、104与除颤仪主体101电连接,这样可以利用除颤仪实现按压参数的辅助测量。加速度传感器102用于获取胸外按压校准过程的参考加速度信号,当然加速度传感器102也可用于获取胸外按压测量过程的实时加速度信号。电极片103、104用于获取胸外按压校准过程的参考胸腔阻抗信号和胸外按压测量过程的实时胸腔阻抗信号。监测过程中施加在被监测对象身上的加速度传感器和电极片(例如2个)如图7所示。其中加速度传感器设置于被监测对象的胸腔正上方,施救者通过加速度传感器102将压力实施于被监测对象。两个电极片103、104分别设置在被监测对象的胸腔外侧,并利用除颤仪主体101自身所带的阻抗测量电路实现胸腔阻抗的测量。以上信号采集过程中,测量胸腔阻抗信号无需采用单独的一套传感器和检测电路,系统复杂度相比配合使用加速度传感器和力传感器的现有技术可明显降低。The acceleration sensor 102 and the electrode sheets 103, 104 are electrically connected to the defibrillator body 101, so that the auxiliary measurement of the pressing parameter can be realized by the defibrillator. The acceleration sensor 102 is used to obtain a reference acceleration signal of the chest compression calibration process. Of course, the acceleration sensor 102 can also be used to acquire a real-time acceleration signal of the chest compression measurement process. The electrode sheets 103, 104 are used to obtain a reference chest impedance signal of the chest compression calibration process and a real-time chest impedance signal of the chest compression measurement process. The acceleration sensor and the electrode sheets (for example, two) applied to the object to be monitored during the monitoring are as shown in FIG. The acceleration sensor is disposed directly above the chest of the object to be monitored, and the rescuer applies pressure to the object to be monitored through the acceleration sensor 102. The two electrode sheets 103, 104 are respectively disposed outside the chest of the object to be monitored, and the impedance measurement circuit of the defibrillator body 101 itself is used to measure the chest impedance. In the above signal acquisition process, the measurement of the thoracic impedance signal does not require a separate set of sensors and detection circuits, and the system complexity can be significantly reduced compared to the prior art using the acceleration sensor and the force sensor.
另外,除颤仪主体101还包括与按压深度计算单元13电连接的除颤强度调控单元。胸外按压通常在体外除颤前执行,通过按压深度的监测可以在一定程度上反映CPR效果。在进行初次除颤时可根据按压深度的具体值和/或变化趋势适当调控除颤电流量,保证除颤效果的同时最大程度降低对心肌的损伤。本发明的除颤仪10由于提高了按压深度监测的精确性,因此可为除颤强度的调控提供更为可靠的指导效果。In addition, the defibrillator main body 101 further includes a defibrillation intensity adjusting unit electrically connected to the pressing depth calculating unit 13. Chest compression is usually performed before defibrillation in vitro, and the CPR effect can be reflected to some extent by monitoring the compression depth. In the initial defibrillation, the amount of defibrillation current can be appropriately adjusted according to the specific value and/or the trend of the compression depth, and the defibrillation effect is ensured while the damage to the myocardium is minimized. The defibrillator 10 of the present invention can provide a more reliable guiding effect for the regulation of defibrillation intensity by improving the accuracy of the compression depth monitoring.
除以上所提及的按压深度、按压频率和按压时间间隔以外,本发明同样可以监测人工呼吸通气度等参数。将这些按压参数及时反馈给施救者可以指导施救者实施高质量的CPR急救措施。In addition to the above-mentioned compression depth, compression frequency, and compression time interval, the present invention can also monitor parameters such as artificial respiratory ventilation. Feedback of these compression parameters to the rescuer in a timely manner can guide the rescuer to implement high quality CPR first aid measures.
另外,以上虽然描述了胸腔阻抗和按压深度的相关性,但由于按压深度由加速度信号计算得到,因此胸腔阻抗和按压深度的相关性也可间接反映胸腔阻抗和加速度信号的相关性。本发明的相关性确定步骤或相关性确定单元并不局限于仅确定按压深度和胸腔阻抗的相关性,基于胸腔阻抗和加速度信号的关联进行的按压参数监测同样包括在本发明的范围内。In addition, although the correlation between the chest impedance and the compression depth is described above, since the compression depth is calculated from the acceleration signal, the correlation between the chest impedance and the compression depth may also indirectly reflect the correlation between the chest impedance and the acceleration signal. The correlation determining step or correlation determining unit of the present invention is not limited to determining only the correlation between the pressing depth and the chest impedance, and the pressing parameter monitoring based on the correlation of the chest impedance and the acceleration signal is also included in the scope of the present invention.
还需要说明的是,以上描述中虽然区分了“实时加速度信号”和“参考加速度信号”、以及“实时胸腔阻抗信号”和“参考加速度阻抗信号”,但通过对除颤仪的说明可知,加速度信号均由加速度传感器获取,胸腔阻抗信号均由电极片获取,描述上的区分只是突出了信号获取阶段的区别,并不是表示实时和参考信号具有不同来源、不同获取途径或不同属性。因此通过校准过程确定的相关性可以应用于测量过程的对应计算。It should also be noted that although the above description distinguishes between "real-time acceleration signal" and "reference acceleration signal", and "real-time chest impedance signal" and "reference acceleration impedance signal", it can be known from the description of the defibrillator that the acceleration The signals are obtained by the acceleration sensor, and the chest impedance signals are all acquired by the electrode sheets. The distinction in the description only highlights the difference in the signal acquisition stage, and does not indicate that the real-time and reference signals have different sources, different acquisition paths or different attributes. The correlation determined by the calibration process can therefore be applied to the corresponding calculation of the measurement process.
以上所述实施例仅表达了本发明的几种实施方式,其描述较为具体和详细,但并不能因此而理解为对本发明专利范围的限制。应当指出的是,对于本领域的普通技术人员来说,在不脱离本发明构思的前提下,还可以做出若干变形和改进,这些都属于本发明的保护范围。因此,本发明专利的保护范围应以所附权利要求为准。The above-mentioned embodiments are merely illustrative of several embodiments of the present invention, and the description thereof is more specific and detailed, but is not to be construed as limiting the scope of the invention. It should be noted that a number of variations and modifications may be made by those skilled in the art without departing from the spirit and scope of the invention. Therefore, the scope of the invention should be determined by the appended claims.

Claims (14)

  1. 一种胸外按压深度的监测方法,其特征在于,包括:A method for monitoring the depth of chest compression, characterized in that it comprises:
    获取胸外按压校准过程的参考加速度信号和参考胸腔阻抗信号;Obtaining a reference acceleration signal and a reference chest impedance signal of the chest compression calibration process;
    使用所述参考加速度信号计算参考按压深度,并确定所述参考胸腔阻抗信号与所述参考按压深度的相关性;Calculating a reference compression depth using the reference acceleration signal, and determining a correlation of the reference chest impedance signal with the reference compression depth;
    获取胸外按压测量过程的实时胸腔阻抗信号;以及Obtaining a real-time chest impedance signal from the chest compression measurement process;
    使用所述实时胸腔阻抗信号和确定的所述相关性计算胸外按压测量过程的按压深度。The compression depth of the chest compression measurement process is calculated using the real-time chest impedance signal and the determined correlation.
  2. 根据权利要求1所述的胸外按压深度的监测方法,其特征在于,所述相关性为所述参考胸腔阻抗信号的测量值与所述参考按压深度的直接相关性或者所述参考胸腔阻抗信号的变化值与所述参考按压深度的间接相关性。The method for monitoring the chest compression depth according to claim 1, wherein the correlation is a direct correlation between the measured value of the reference chest impedance signal and the reference compression depth or the reference chest impedance signal The indirect correlation of the change value with the reference compression depth.
  3. 根据权利要求2所述的胸外按压深度的监测方法,其特征在于,所述直接相关性为:The method for monitoring the chest compression depth according to claim 2, wherein the direct correlation is:
    S=K1×Z;S=K1×Z;
    其中,S表示按压深度,Z表示胸腔阻抗信号的测量值,K1表示按压深度与胸腔阻抗信号的测量值的比值。Where S represents the compression depth, Z represents the measured value of the chest impedance signal, and K1 represents the ratio of the compression depth to the measured value of the chest impedance signal.
  4. 根据权利要求2所述的胸外按压深度的监测方法,其特征在于,所述间接相关性为:The method of monitoring the chest compression depth according to claim 2, wherein the indirect correlation is:
    S=K2 ×△ Z;S=K2 ×△ Z;
    其中,S表示按压深度; △ Z表示胸腔阻抗信号的变化值,K2表示按压深度与胸腔阻抗信号的变化值的比值。Where S represents the depth of compression; Z represents the change value of the chest impedance signal, and K2 represents the ratio of the compression depth to the change value of the chest impedance signal.
  5. 根据权利要求1所述的胸外按压深度的监测方法,其特征在于,在使用所述实时胸腔阻抗信号和确定的所述相关性计算胸外按压测量过程的按压深度之前,所述监测方法还包括:The method of monitoring the chest compression depth according to claim 1, wherein the monitoring method further calculates a compression depth of the chest compression measurement process using the real-time chest impedance signal and the determined correlation. include:
    获取胸外按压测量过程的实时加速度信号,以及Obtain real-time acceleration signals from the chest compression measurement process, and
    确定胸外按压测量过程的外界环境。Determine the external environment of the chest compression measurement process.
  6. 根据权利要求5所述的胸外按压深度的监测方法,其特征在于,确定胸外按压测量过程的外界环境包括:The method for monitoring the chest compression depth according to claim 5, wherein the external environment for determining the chest compression measurement process comprises:
    在所述实时加速度信号为非零值、且所述实时胸腔阻抗信号发生变化时,确定胸外按压测量过程的外界环境为静止环境;在所述实时加速度信号为非零值、且所述实时胸腔阻抗信号保持不变时,确定胸外按压测量过程的外界环境为运动环境。When the real-time acceleration signal is non-zero and the real-time chest impedance signal changes, determining that the external environment of the chest compression measurement process is a static environment; the real-time acceleration signal is non-zero, and the real-time When the thoracic impedance signal remains unchanged, it is determined that the external environment of the chest compression measurement process is a sports environment.
  7. 根据权利要求6所述的胸外按压深度的监测方法,其特征在于,在确定胸外按压测量过程的外界环境后,计算胸外按压测量过程的按压深度包括:The method for monitoring the chest compression depth according to claim 6, wherein after determining the external environment of the chest compression measurement process, calculating the compression depth of the chest compression measurement process comprises:
    在所述胸外按压测量过程的外界环境为运动环境时,使用所述实时胸腔阻抗信号和确定的所述相关性计算胸外按压测量过程的按压深度;When the external environment of the chest compression measurement process is a sports environment, the real-time chest impedance signal and the determined correlation are used to calculate a compression depth of the chest compression measurement process;
    在所述胸外按压测量过程的外界环境为静止环境时,使用所述实时加速度信号计算胸外按压测量过程的按压深度。When the external environment of the chest compression measurement process is a stationary environment, the real-time acceleration signal is used to calculate the compression depth of the chest compression measurement process.
  8. 一种胸外按压深度的监测系统,其特征在于,包括:A monitoring system for chest compression depth, characterized in that it comprises:
    信号获取单元,用于获取胸外按压校准过程的参考加速度信号和参考胸腔阻抗信号,以及用于获取胸外按压测量过程的实时胸腔阻抗信号;a signal acquisition unit, configured to obtain a reference acceleration signal and a reference chest impedance signal of the chest compression calibration process, and a real-time chest impedance signal for acquiring the chest compression measurement process;
    相关性确定单元,用于使用所述参考加速度信号计算参考按压深度,并确定所述参考胸腔阻抗信号与所述参考按压深度的相关性;及按压深度计算单元,用于使用所述实时胸腔阻抗信号和确定的所述相关性计算胸外按压测量过程的按压深度。a correlation determining unit, configured to calculate a reference pressing depth using the reference acceleration signal, and determine a correlation between the reference chest impedance signal and the reference pressing depth; and a pressing depth calculating unit configured to use the real-time chest impedance The signal and the determined correlation are used to calculate the depth of compression of the chest compression measurement process.
  9. 根据权利要求8所述的胸外按压深度的监测系统,其特征在于,所述相关性为参考胸腔阻抗信号的测量值与所述参考按压深度的直接相关性或者参考胸腔阻抗信号的变化值与所述参考按压深度的间接相关性。The monitoring system for chest compression depth according to claim 8, wherein the correlation is a direct correlation between a measured value of a reference chest impedance signal and the reference compression depth or a reference value of a reference value of a chest impedance signal. The indirect correlation of the reference compression depth.
  10. 根据权利要求8所述的胸外按压深度的监测系统,其特征在于,所述监测系统还包括外界环境确定单元,用于确定胸外按压测量过程的外界环境。The monitoring system for chest compression depth according to claim 8, wherein the monitoring system further comprises an external environment determining unit for determining an external environment of the chest compression measuring process.
  11. 根据权利要求10所述的胸外按压深度的监测系统,其特征在于,所述信号获取单元还用于获取胸外按压测量过程的实时加速度信号;The monitoring system for the chest compression depth according to claim 10, wherein the signal acquisition unit is further configured to acquire a real-time acceleration signal of the chest compression measurement process;
    在所述外界环境确定单元确定所述胸外按压测量过程的外界环境为运动环境时,所述按压深度计算单元使用所述实时胸腔阻抗信号和确定的所述相关性计算胸外按压测量过程的按压深度;在所述外界环境确定单元确定所述胸外按压测量过程的外界环境为静止环境时,所述按压深度计算单元使用所述实时加速度信号计算胸外按压测量过程的按压深度。When the external environment determining unit determines that the external environment of the chest compression measurement process is a sports environment, the pressing depth calculation unit calculates the chest compression measurement process using the real-time chest impedance signal and the determined correlation Pressing the depth; when the external environment determining unit determines that the external environment of the chest compression measurement process is a stationary environment, the pressing depth calculation unit calculates the pressing depth of the chest compression measurement process using the real-time acceleration signal.
  12. 根据权利要求8所述的胸外按压深度的监测系统,其特征在于,还包括一被监测对象判断单元,所述被监测对象判断单元用于判断被监测对象是否发生变化。The monitoring system for the chest compression depth according to claim 8, further comprising a monitored object determining unit, wherein the monitored object determining unit is configured to determine whether the monitored object has changed.
  13. 一种除颤仪,包括除颤仪主体、与所述除颤仪主体电连接的加速度传感器,及至少两个电极片;所述加速度传感器用于采集胸外按压校准过程的参考加速度信号,所述电极片用于采集胸外按压校准过程的参考胸腔阻抗信号和胸外按压测量过程的实时胸腔阻抗信号;其特征在于,所述除颤仪主体还包括如权利要求8所述的胸外按压深度的监测系统。A defibrillator comprising a defibrillator body, an acceleration sensor electrically connected to the defibrillator body, and at least two electrode sheets; the acceleration sensor is configured to collect a reference acceleration signal of a chest compression calibration process, The electrode sheet is used for acquiring a reference chest impedance signal of the chest compression calibration process and a real-time chest impedance signal of the chest compression measurement process; wherein the defibrillator body further comprises the chest compression according to claim 8. Deep monitoring system.
  14. 根据权利要求13所述的除颤仪,其特征在于,还包括与所述按压深度计算单元电连接的除颤强度调控单元,用于根据按压深度的具体值和/或变化趋势适当调控除颤电流量。The defibrillator according to claim 13, further comprising a defibrillation intensity adjusting unit electrically connected to said pressing depth calculating unit for appropriately regulating defibrillation according to a specific value and/or a trend of the pressing depth Electricity flow.
PCT/CN2014/074069 2013-07-07 2014-03-26 Method and system for monitoring depth of external chest compression and defibrillator WO2015003509A1 (en)

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