WO2014197713A3 - Molecular phenotyping of idiopathic interstitial pneumonia identifies two subtypes of idiopathic pulmonary fibrosis - Google Patents

Molecular phenotyping of idiopathic interstitial pneumonia identifies two subtypes of idiopathic pulmonary fibrosis Download PDF

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Publication number
WO2014197713A3
WO2014197713A3 PCT/US2014/041129 US2014041129W WO2014197713A3 WO 2014197713 A3 WO2014197713 A3 WO 2014197713A3 US 2014041129 W US2014041129 W US 2014041129W WO 2014197713 A3 WO2014197713 A3 WO 2014197713A3
Authority
WO
WIPO (PCT)
Prior art keywords
idiopathic
subtypes
identifies
pulmonary fibrosis
interstitial pneumonia
Prior art date
Application number
PCT/US2014/041129
Other languages
French (fr)
Other versions
WO2014197713A2 (en
Inventor
Ivana V. Yang
Christopher D. Coldren
David A. Schwartz
Original Assignee
The Regents Of The University Of Colorado, A Body Corporate
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of Colorado, A Body Corporate filed Critical The Regents Of The University Of Colorado, A Body Corporate
Publication of WO2014197713A2 publication Critical patent/WO2014197713A2/en
Publication of WO2014197713A3 publication Critical patent/WO2014197713A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Nucleic acids, devices, and methods that aid in identifying novel sub-types of pulmonary disease are disclosed. In some embodiments, the pulmonary disease is Idiopathic Pulmonary Fibrosis (IPF) and the subtypes are designated IPF subtype I and IPF subtype II.
PCT/US2014/041129 2013-06-05 2014-06-05 Molecular phenotyping of idiopathic interstitial pneumonia identifies two subtypes of idiopathic pulmonary fibrosis WO2014197713A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361831379P 2013-06-05 2013-06-05
US61/831,379 2013-06-05

Publications (2)

Publication Number Publication Date
WO2014197713A2 WO2014197713A2 (en) 2014-12-11
WO2014197713A3 true WO2014197713A3 (en) 2015-02-12

Family

ID=52008751

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2014/041129 WO2014197713A2 (en) 2013-06-05 2014-06-05 Molecular phenotyping of idiopathic interstitial pneumonia identifies two subtypes of idiopathic pulmonary fibrosis

Country Status (1)

Country Link
WO (1) WO2014197713A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114694748B (en) * 2022-02-22 2022-10-28 中国人民解放军军事科学院军事医学研究院 Proteomics molecular typing method based on prognosis information and reinforcement learning

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070099251A1 (en) * 2005-10-17 2007-05-03 Institute For Systems Biology Tissue-and serum-derived glycoproteins and methods of their use
WO2009073167A2 (en) * 2007-12-03 2009-06-11 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Identification and diagnosis of pulmonary fibrosis using mucin genes, and related methods and compositions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070099251A1 (en) * 2005-10-17 2007-05-03 Institute For Systems Biology Tissue-and serum-derived glycoproteins and methods of their use
WO2009073167A2 (en) * 2007-12-03 2009-06-11 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Identification and diagnosis of pulmonary fibrosis using mucin genes, and related methods and compositions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
YANG ET AL.: "Epigenomics of idiopathic pulmonary fibrosis", EPIGENOMICS, vol. 4, no. 2, April 2012 (2012-04-01), pages 195 - 203 *

Also Published As

Publication number Publication date
WO2014197713A2 (en) 2014-12-11

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WO2014197713A3 (en) Molecular phenotyping of idiopathic interstitial pneumonia identifies two subtypes of idiopathic pulmonary fibrosis

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