WO2014186728A3 - Methods for diagnosing and treating inflammatory bowel disease - Google Patents
Methods for diagnosing and treating inflammatory bowel disease Download PDFInfo
- Publication number
- WO2014186728A3 WO2014186728A3 PCT/US2014/038434 US2014038434W WO2014186728A3 WO 2014186728 A3 WO2014186728 A3 WO 2014186728A3 US 2014038434 W US2014038434 W US 2014038434W WO 2014186728 A3 WO2014186728 A3 WO 2014186728A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- inflammatory bowel
- disease
- diagnosing
- bowel disease
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BR112015028338A BR112015028338A2 (en) | 2013-05-17 | 2014-05-16 | methods of diagnosis or aid in the diagnosis and treatment of inflammatory bowel disease |
KR1020157032445A KR20160005044A (en) | 2013-05-17 | 2014-05-16 | Methods for diagnosing and treating inflammatory bowel disease |
CN201480028634.6A CN105209643A (en) | 2013-05-17 | 2014-05-16 | Methods for diagnosing and treating inflammatory bowel disease |
JP2016514135A JP2016521540A (en) | 2013-05-17 | 2014-05-16 | Diagnosis and treatment method for inflammatory bowel disease |
CA2910199A CA2910199A1 (en) | 2013-05-17 | 2014-05-16 | Methods for diagnosing and treating inflammatory bowel disease |
RU2015149032A RU2015149032A (en) | 2013-05-17 | 2014-05-16 | METHODS FOR DIAGNOSIS AND TREATMENT OF INFLAMMATORY DISEASES OF THE GUT |
MX2015015784A MX2015015784A (en) | 2013-05-17 | 2014-05-16 | Methods for diagnosing and treating inflammatory bowel disease. |
EP14797054.5A EP2997162A4 (en) | 2013-05-17 | 2014-05-16 | Methods for diagnosing and treating inflammatory bowel disease |
US14/944,147 US20160178644A1 (en) | 2013-05-17 | 2015-11-17 | Methods for diagnosing and treating inflammatory bowel disease |
HK16107516.2A HK1219512A1 (en) | 2013-05-17 | 2016-06-28 | Methods for diagnosing and treating inflammatory bowel disease |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361824661P | 2013-05-17 | 2013-05-17 | |
US61/824,661 | 2013-05-17 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US14/944,147 Continuation US20160178644A1 (en) | 2013-05-17 | 2015-11-17 | Methods for diagnosing and treating inflammatory bowel disease |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2014186728A2 WO2014186728A2 (en) | 2014-11-20 |
WO2014186728A3 true WO2014186728A3 (en) | 2015-01-22 |
Family
ID=51899021
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2014/038434 WO2014186728A2 (en) | 2013-05-17 | 2014-05-16 | Methods for diagnosing and treating inflammatory bowel disease |
Country Status (11)
Country | Link |
---|---|
US (1) | US20160178644A1 (en) |
EP (1) | EP2997162A4 (en) |
JP (1) | JP2016521540A (en) |
KR (1) | KR20160005044A (en) |
CN (1) | CN105209643A (en) |
BR (1) | BR112015028338A2 (en) |
CA (1) | CA2910199A1 (en) |
HK (1) | HK1219512A1 (en) |
MX (1) | MX2015015784A (en) |
RU (1) | RU2015149032A (en) |
WO (1) | WO2014186728A2 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107530431B (en) | 2015-01-29 | 2022-01-07 | 牛津大学创新有限公司 | Biomarkers |
GB201616557D0 (en) * | 2016-09-29 | 2016-11-16 | Secretary Of State For Health The | Assay for distinguishing between sepsis and systemic inflammatory response syndrome |
CA3047302C (en) * | 2016-12-14 | 2024-01-02 | Tracy WARREN | System and methods for developing and using a microbiome-based action component for patient health |
US11978543B2 (en) | 2016-12-14 | 2024-05-07 | Astarte Medical Partners Inc. | System and methods for developing and using a microbiome-based action component |
US11840565B2 (en) | 2016-12-29 | 2023-12-12 | University Of Miami | Methods and compositions for treating virus-associated inflammation |
CN110461356A (en) * | 2016-12-29 | 2019-11-15 | 迈阿密大学 | Method for adjusting inflammatory body activity and inflammation in lung |
EP3654993A4 (en) * | 2017-07-17 | 2021-08-25 | The Broad Institute, Inc. | Cell atlas of the healthy and ulcerative colitis human colon |
CN111212851A (en) * | 2017-07-18 | 2020-05-29 | 华盛顿大学 | Methods and uses of inflammatory bowel disease biomarkers |
GB201717301D0 (en) * | 2017-10-20 | 2017-12-06 | Nordic Bioscience As | Type xvi collagen assay |
WO2019155050A1 (en) * | 2018-02-12 | 2019-08-15 | F. Hoffmann-La Roche Ag | Method of predicting response to therapy by assessing tumor genetic heterogeneity |
CA3121167A1 (en) * | 2018-11-29 | 2020-06-04 | Cedars-Sinai Medical Center | Methods of stratifying and treating a sub-population of inflammatory bowel disease patients |
WO2020241778A1 (en) * | 2019-05-29 | 2020-12-03 | 国立大学法人九州大学 | Pharmaceutical composition for suppressing fibrosis |
KR102577697B1 (en) * | 2019-11-13 | 2023-09-14 | 주식회사 나이벡 | Peptides for Inflammation Treatment and Wound healing |
US20230279491A1 (en) * | 2020-06-03 | 2023-09-07 | Cedars-Sinai Medical Center | Treatments for a sub-population of inflammatory bowel disease patients |
WO2022140667A2 (en) * | 2020-12-23 | 2022-06-30 | Icahn School Of Medicine At Mount Sinai | Method for treating crohn's disease |
EP4371573A1 (en) | 2021-07-13 | 2024-05-22 | National University Corporation Tokai National Higher Education and Research System | Medicinal composition for treating inflammatory bowel disease |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005009339A2 (en) * | 2003-05-30 | 2005-02-03 | Pathway Diagnostics Corporation, Inc. (a Delaware Corporation) | Inflammatory bowel diseases |
US20100093552A1 (en) * | 2008-10-09 | 2010-04-15 | Asit Panja | Use and identification of biomarkers for gastrointestinal diseases |
US20110033486A1 (en) * | 2009-07-20 | 2011-02-10 | Abbas Alexander R | Gene expression markers for crohn's disease |
US20110045476A1 (en) * | 2009-04-14 | 2011-02-24 | Prometheus Laboratories Inc. | Inflammatory bowel disease prognostics |
WO2012021773A1 (en) * | 2010-08-13 | 2012-02-16 | Genentech, Inc. | Antibodies to il-1beta and il-18, for treatment of disease |
-
2014
- 2014-05-16 BR BR112015028338A patent/BR112015028338A2/en not_active Application Discontinuation
- 2014-05-16 KR KR1020157032445A patent/KR20160005044A/en not_active Application Discontinuation
- 2014-05-16 JP JP2016514135A patent/JP2016521540A/en active Pending
- 2014-05-16 RU RU2015149032A patent/RU2015149032A/en not_active Application Discontinuation
- 2014-05-16 EP EP14797054.5A patent/EP2997162A4/en not_active Withdrawn
- 2014-05-16 CN CN201480028634.6A patent/CN105209643A/en active Pending
- 2014-05-16 MX MX2015015784A patent/MX2015015784A/en unknown
- 2014-05-16 WO PCT/US2014/038434 patent/WO2014186728A2/en active Application Filing
- 2014-05-16 CA CA2910199A patent/CA2910199A1/en not_active Abandoned
-
2015
- 2015-11-17 US US14/944,147 patent/US20160178644A1/en not_active Abandoned
-
2016
- 2016-06-28 HK HK16107516.2A patent/HK1219512A1/en unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005009339A2 (en) * | 2003-05-30 | 2005-02-03 | Pathway Diagnostics Corporation, Inc. (a Delaware Corporation) | Inflammatory bowel diseases |
US20100093552A1 (en) * | 2008-10-09 | 2010-04-15 | Asit Panja | Use and identification of biomarkers for gastrointestinal diseases |
US20110045476A1 (en) * | 2009-04-14 | 2011-02-24 | Prometheus Laboratories Inc. | Inflammatory bowel disease prognostics |
US20110033486A1 (en) * | 2009-07-20 | 2011-02-10 | Abbas Alexander R | Gene expression markers for crohn's disease |
WO2012021773A1 (en) * | 2010-08-13 | 2012-02-16 | Genentech, Inc. | Antibodies to il-1beta and il-18, for treatment of disease |
Non-Patent Citations (1)
Title |
---|
MCKAIG ET AL.: "Differential expression of TGF-b isoforms by normal and inflammatory bowel disease intestinal myofibroblasts", AM J PHYSIOL CELL PHYSIOL, vol. 282, 2002, pages C172 - C182, XP003003258 * |
Also Published As
Publication number | Publication date |
---|---|
JP2016521540A (en) | 2016-07-25 |
BR112015028338A2 (en) | 2017-07-25 |
RU2015149032A (en) | 2017-06-22 |
EP2997162A4 (en) | 2017-02-01 |
CN105209643A (en) | 2015-12-30 |
US20160178644A1 (en) | 2016-06-23 |
WO2014186728A2 (en) | 2014-11-20 |
CA2910199A1 (en) | 2014-11-20 |
MX2015015784A (en) | 2016-03-11 |
KR20160005044A (en) | 2016-01-13 |
EP2997162A2 (en) | 2016-03-23 |
HK1219512A1 (en) | 2017-04-07 |
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