WO2014131179A1 - 伽玛刀头部治疗装置及伽玛刀治疗系统 - Google Patents

伽玛刀头部治疗装置及伽玛刀治疗系统 Download PDF

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Publication number
WO2014131179A1
WO2014131179A1 PCT/CN2013/072001 CN2013072001W WO2014131179A1 WO 2014131179 A1 WO2014131179 A1 WO 2014131179A1 CN 2013072001 W CN2013072001 W CN 2013072001W WO 2014131179 A1 WO2014131179 A1 WO 2014131179A1
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Prior art keywords
gamma knife
cbct
head
treatment device
module
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PCT/CN2013/072001
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English (en)
French (fr)
Inventor
吴中华
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深圳市奥沃医学新技术发展有限公司
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Priority to PCT/CN2013/072001 priority Critical patent/WO2014131179A1/zh
Priority to CN201380004400.3A priority patent/CN104203347B/zh
Publication of WO2014131179A1 publication Critical patent/WO2014131179A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/40—Arrangements for generating radiation specially adapted for radiation diagnosis
    • A61B6/4064—Arrangements for generating radiation specially adapted for radiation diagnosis specially adapted for producing a particular type of beam
    • A61B6/4085—Cone-beams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/02—Arrangements for diagnosis sequentially in different planes; Stereoscopic radiation diagnosis
    • A61B6/03—Computed tomography [CT]
    • A61B6/032—Transmission computed tomography [CT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/12—Arrangements for detecting or locating foreign bodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1077—Beam delivery systems
    • A61N5/1084—Beam delivery systems for delivering multiple intersecting beams at the same time, e.g. gamma knives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/40—Arrangements for generating radiation specially adapted for radiation diagnosis
    • A61B6/4021—Arrangements for generating radiation specially adapted for radiation diagnosis involving movement of the focal spot
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B6/00—Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment
    • A61B6/42—Arrangements for detecting radiation specially adapted for radiation diagnosis
    • A61B6/4208—Arrangements for detecting radiation specially adapted for radiation diagnosis characterised by using a particular type of detector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1048—Monitoring, verifying, controlling systems and methods
    • A61N5/1049—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam
    • A61N2005/1061—Monitoring, verifying, controlling systems and methods for verifying the position of the patient with respect to the radiation beam using an x-ray imaging system having a separate imaging source

Definitions

  • the invention belongs to the field of medical radiation, and particularly relates to a gamma knife head treatment device and a gamma knife treatment system. Background technique
  • Gamma Knife is a very advanced radiotherapy device. Its full name is gamma ray stereotactic therapy system. It is a therapeutic device that combines modern computer technology, stereotactic technology and surgical technology. It will emit radioactive sources. The gamma ray is geometrically focused, concentrated on the tumor, and one-time and fatal to destroy the tissue within the target.
  • the existing gamma knife treatment device is fixed by a gamma knife head treatment invasive positioning device (for example, a nail) as shown in Fig. 1, due to the patient's head tumor and nail There is a certain distance between the nail and the U-shaped holder of the treatment bed. Therefore, the size of the patient's head tumor relative to the device is converted by the size chain, there will be some error, and the actual positioning will be reduced. Precision. And invasive positioning will also increase the pain of patient treatment. In addition, the dose rate at the focus of the gamma knife is relatively low. Because the existing gamma knife head treatment uses an invasive positioning device to fix the patient, it cannot treat patients with excessive head tumors.
  • a gamma knife head treatment invasive positioning device for example, a nail
  • An object of the present invention is to provide a gamma knife head treatment device and a gamma knife treatment system, which are directed to It solves the problem that the existing gamma knife treatment device cannot treat patients requiring fractional treatment and has low precision during treatment.
  • a gamma knife head treatment device including a radiation source and a carrier body, the radiation source being mounted on the carrier body for emitting a plurality of geometrically focusable and focal points Gamma ray
  • the gamma knife head treatment device further comprises a CBCT image module
  • the CBCT image module comprises a CBCT bulb and a dynamic flat panel detector, wherein: the CBCT bulb is mounted on the And a dynamic flat panel detector mounted on the carrier body on a side opposite to the CBCT bulb, wherein the CBCT bulb is vertically connected to the dynamic flat panel detector
  • the line passes through the focus or has a known fixed size position with the focus.
  • the CBCT bulb is used to emit X-rays; and the dynamic flat panel detector is configured to collect projection data of the X-rays.
  • the CBCT image module can rotate 360 degrees around a patient's head on a circular trajectory.
  • the source is a cobalt source.
  • the shape of the carrier is a disk, a hemisphere, a cylinder or the like.
  • the CBCT bulb is mounted on the carrier by a positioning pin and a threaded connection.
  • the gamma knife head treatment device uses a head and shoulder membrane to fix the patient's head.
  • the gamma knife head treatment device further includes a three-dimensional data reconstruction module, an analysis comparison module, and a control module, wherein: the three-dimensional data reconstruction module is connected to the CBCT image module and the Receiving the projection data transmitted by the CBCT image module, and performing analysis and reconstruction according to the projection data to obtain three-dimensional data of the head of the patient's current body position, and transmitting the three-dimensional data of the head to the analysis.
  • the three-dimensional data reconstruction module is connected to the CBCT image module and the Receiving the projection data transmitted by the CBCT image module, and performing analysis and reconstruction according to the projection data to obtain three-dimensional data of the head of the patient's current body position, and transmitting the three-dimensional data of the head to the analysis.
  • a comparison module configured to receive the three-dimensional data of the head sent by the three-dimensional data reconstruction module, and the head Comparing the three-dimensional data with the three-dimensional data used by the treatment plan, calculating a deviation value of the three-dimensional data of the head from the three-dimensional data used by the treatment plan, and transmitting the deviation value to the control module
  • the control module Connected to the analysis comparison module, configured to receive the deviation value sent by the analysis comparison module, and if the deviation value is less than a threshold value, start treating the patient.
  • the control module performs a position correction on the patient according to the deviation value, and records the corrected three-dimensional stereo data, and after the position correction, controls the The CBCT image module acquires new projection data based on the corrected position.
  • Another object of the present invention is to provide a gamma knife treatment system comprising the gamma knife head treatment device described above.
  • the gamma knife head treatment device and the gamma knife treatment system provided by the invention can realize high-precision positioning of the head tumor through the CBCT image module, and can realize small-dose fractional treatment of the head tumor, and maximize protection. The patient's normal tissue is exposed.
  • Figure 1 is a prior art gamma knife head treatment invasive positioning device
  • FIG. 2 is a schematic structural view of a rotary treatment head in a conventional gamma knife head treatment device
  • FIG. 3 is a schematic view showing the structure of a rotary treatment head in a gamma knife head treatment device according to an embodiment of the present invention
  • FIG. 4 is a block diagram showing the structure of a gamma knife head treatment apparatus according to an embodiment of the present invention. detailed description
  • FIG. 2 is a schematic structural view of a rotary treatment head in a conventional gamma knife head treatment device.
  • the rotary treatment head of the prior gamma knife head treatment device includes: a cobalt source 120 and a carrier body 130.
  • the cobalt source 120 is mounted on the carrier 130, which emits a plurality of gamma rays and geometrically focuses them to form a focus 110.
  • the gamma knife treatment device Before using the gamma knife treatment device, it is necessary to determine the specific position of the patient's head tumor relative to the invasive positioning device by using other inspection imaging devices to fix the patient's head according to the specific location of the patient's head tumor at the invasive positioning device. In this way, it is necessary to determine the target and dose at one time, and it is impossible to treat patients who require fractional treatment.
  • Fig. 3 is a schematic view showing the structure of a rotary treatment head in a gamma knife head treatment device according to an embodiment of the present invention.
  • the rotary treatment head of the gamma knife head treatment device provided by the present invention comprises: a radiation source 220, a carrier body 230, and a Cone Beam Computed Tomography (CBCT) tube. 240, and a dynamic flat panel detector 250.
  • CBCT Cone Beam Computed Tomography
  • the radiation source 220 is mounted on the carrier body 230, which emits a plurality of gamma rays, and geometrically focuses them to form a focus (ie, isocenter) 210, wherein the radiation source 220 can be a cobalt source, and the source body 230
  • the shape may be a disk, a hemisphere, or a cylinder.
  • the CBCT bulb 240 is mounted on the carrier 230 for emitting X-rays.
  • the CBCT bulb 240 can be connected to the carrier 230 by a variety of connections, such as: locating pins and threaded connections.
  • the dynamic flat panel detector 250 is also mounted on the carrier 230, on the opposite side of the CBCT bulb 240.
  • the vertical connection of the CBCT bulb 240 to the dynamic flat panel detector 250 passes through the focus 210 or has a known fixed size with the focus 210.
  • Position that is, the distance between the vertical connection line of the CBCT bulb 240 and the dynamic flat panel detector 250 and the focus 210 is a fixed size, for example: 50 mm, 100 mm, 300 mm, or 500 mm.
  • the dynamic flat panel detector 250 is used to collect the projection data of the X-rays, so as to use the projection data for analysis and reconstruction, and obtain the three-dimensional data of the head of the patient's current body position.
  • the CBCT tube 240 and the dynamic flat panel detector 250 form a CBCT image module 310 that can be rotated 360 degrees around a patient's head on a circular path.
  • the gamma knife head treatment device 300 provided by the present invention includes a CBCT image module 310, a three-dimensional data reconstruction module 320, an analysis comparison module 330, and a control module 340.
  • the CBCT image module 310 is composed of a CBCT bulb 240 and a dynamic flat panel detector 250, which is coupled to the three-dimensional data reconstruction module 320 for 360-degree rotation on a circular trajectory around the patient's head to acquire X-ray projection data. And transmitting the projection data to the three-dimensional data reconstruction module 320.
  • the three-dimensional data reconstruction module 320 is connected to the CBCT image module 310 and the analysis comparison module 330, and is configured to receive projection data transmitted by the CBCT image module 310, and perform analysis and reconstruction according to the projection data to obtain a three-dimensional head of the patient's current body position. Data, and the header three-dimensional data is sent to the analysis comparison module 330.
  • the analysis comparison module 330 is connected to the three-dimensional data reconstruction module 320 and the control module 340 for receiving the three-dimensional data of the head of the patient's current body position sent by the three-dimensional data reconstruction module 320, and using the three-dimensional data of the head and the treatment plan.
  • the three-dimensional data ie, the specific location of the patient's head tumor previously determined by other inspection devices
  • the deviation value of the three-dimensional data of the head from the three-dimensional data used by the treatment plan is calculated (ie, The deviation value of the patient's actual position in the gamma knife head treatment device 300 from the planned design request position is transmitted to the control module 340.
  • the control module 340 is connected to the analysis comparison module 330 for receiving the deviation value sent by the analysis comparison module 330. If the deviation value is less than a preset threshold value of the system, the patient is started to be treated.
  • the actual position correction of the patient is performed according to the deviation value, and the corrected three-dimensional stereo data is recorded, and after the position correction (ie, after the coordinate size change is issued), the CBCT image module 310 is controlled to acquire a new position based on the corrected position. Projection data.
  • the gamma knife head treatment device fixes the patient's head by using the non-invasive positioning method of the head and shoulder membrane, thereby reducing the pain caused by the invasive positioning during the treatment of the patient.
  • the gamma knife head treatment device and the gamma knife treatment system provided by the above embodiments of the present invention can realize high-precision positioning of the head tumor through the CBCT image module, and can realize small-dose fractional treatment of the head tumor at the same time. Maximize the patient's normal tissue exposure. In addition, because the patient is fixed by the non-invasive positioning of the head and shoulder membrane, the pain in the patient's treatment process is reduced, and the error caused by the excessive link is avoided.
  • the gamma knife head treatment device and the gamma knife treatment system provided by the present invention can also be used to treat tumors in other body parts of patients, and is not limited to the treatment of the patient's head.
  • the above is only the preferred embodiment of the present invention, and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection of the present invention. Within the scope.

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Abstract

一种伽玛刀头部治疗装置及伽玛刀治疗系统。所述伽玛刀头部治疗装置包括放射源（220）及载源体（230），放射源（220）安装在载源体（230）上，用于发出多束可几何聚焦并形成焦点（210）的伽玛射线。所述伽玛刀头部治疗装置还包括CBCT影像模块（310），所述CBCT影像模块（310）包括CBCT球管（240）以及动态平板探测器（250）。其中，CBCT球管（240）安装在载源体（230）上；动态平板探测器（250）安装在载源体（230）上，位于CBCT球管（240）的对侧。其中，所述CBCT球管（240）与所述动态平板探测器（250）的垂直连接线通过焦点（210）或与所述焦点（210）有已知固定尺寸位置。所述伽玛刀头部治疗装置及伽玛刀治疗系统，通过CBCT影像模块（310）可以实现头部肿瘤的高精度定位，以及对头部肿瘤进行小剂量的分次治疗，尽可能保护病人的正常组织。

Description

伽玛刀头部治疗装置及伽玛刀治疗系统
技术领域
本发明属于医疗放射领域， 尤其涉及一种伽玛刀头部治疗装置及伽玛刀治 疗系统。 背景技术
伽玛刀是一种非常先进的放射治疗设备， 其全称是伽玛射线立体定向治疗 系统， 是一种融合现代计算机技术、 立体定向技术和外科技术于一体的治疗性 设备， 它将放射源发出的伽玛射线几何聚焦， 集中射于肿瘤处， 一次性及致死 性的摧毁靶点内的组织。
现有伽玛刀治疗装置在治疗头部肿瘤时， 是通过如图 1所示的伽玛刀头部 治疗有创定位装置（例如： 脚钉）进行固定， 由于病人头部肿瘤与脚钉之间有 一定的距离， 脚钉与治疗床的 U型固定架之间进行连接， 因此在对病人头部肿 瘤相对于设备位置尺寸是用尺寸链换算出来的， 会存在一定的误差， 降低实际 定位精度。 并且有创定位也会增加病人治疗的痛苦。 另外， 伽玛刀焦点处的剂 量率相对比较低， 由于现有伽玛刀头部治疗是利用有创定位装置来固定病人， 因此不能够治疗头部肿瘤过大的病人。 在使用伽玛刀治疗装置之前， 需要通过 其他的检查影像设备来确定病人头部肿瘤相对创定位装置的具体位置， 以根据 病人头部肿瘤的在创定位装置具体位置来对病人头部进行固定， 且这样一来就 需要一次性确定靶点及剂量， 不能够治疗需要分次治疗的病人。 发明内容 本发明的目的在于提供一种伽玛刀头部治疗装置及伽玛刀治疗系统， 旨在 解决现有的伽玛刀治疗装置不能够治疗需要分次治疗的病人， 且治疗时精度较 低的问题。
本发明是这样实现的， 一种伽玛刀头部治疗装置， 包括放射源及载源体， 所述放射源安装于所述载源体上， 用以发出多束可几何聚焦并形成焦点的伽玛 射线， 其特征在于， 所述伽玛刀头部治疗装置还包括 CBCT影像模块， 所述 CBCT影像模块包括 CBCT球管以及动态平板探测器，其中：所述 CBCT球管， 安装于所述载源体上； 以及所述动态平板探测器， 安装于所述载源体上， 位于 所述 CBCT球管的对一侧， 其中， 所述 CBCT球管与所述动态平板探测器的垂 直连接线通过所述焦点或与所述焦点有已知固定尺寸位置。
较优的， 所述 CBCT球管， 用以发射 X线； 以及所述动态平板探测器， 用 以采集所述 X线的投影数据。
较优的，所述 CBCT影像模块可绕病人头部在一个圆轨迹上做 360度旋转。 较优的， 所述放射源为钴源。
较优的， 所述载源体的形状可以是圆盘、 半球体、 或圆柱体等。
较优的， 所述 CBCT球管是通过定位销及螺纹连接方式安装于所述载源体 上。
较优的， 所述伽玛刀头部治疗装置使用头肩膜对病人头部进行固定。
较优的， 所述伽玛刀头部治疗装置还包括三维数据重建模块、 分析比对模 块、 以及控制模块， 其中： 所述三维数据重建模块， 连接于所述 CBCT影像模 块以及所述， 用于接收所述 CBCT影像模块传送的所述投影数据， 并根据所述 投影数据进行分析重建， 以得到病人当前体位的头部三维立体数据， 并将所述 头部三维立体数据发送到所述分析比对模块； 所述分析比对模块， 连接于所述 三维数据重建模块以及所述控制模块， 用于接收所述三维数据重建模块发送的 所述头部三维立体数据， 并将所述头部三维立体数据与治疗计划使用的三维立 体数据进行比对， 计算出所述头部三维立体数据与所述治疗计划使用的三维立 体数据的偏差值， 并将所述偏差值发送到所述控制模块； 以及所述控制模块， 连接于所述分析比对模块， 用于接收所述分析比对模块发送的所述偏差值， 若 所述偏差值小于门限值时， 开始对病人进行治疗。
较优的， 若所述偏差值大于所述门限值时， 所述控制模块根据所述偏差值 进行对病人位置修正， 并记录已经修正的三维立体数据， 并于位置修正后， 控 制所述 CBCT影像模块在已修正的位置基础上采集新的投影数据。 本发明的另一目的在于提供一种伽玛刀治疗系统， 包括以上所述的伽玛刀 头部治疗装置。 本发明提供的伽玛刀头部治疗装置及伽玛刀治疗系统， 通过 CBCT影像模 块可以实现头部肿瘤的高精度定位， 同时可以实现头部肿瘤的小剂量的分次治 疗， 最大限度地保护病人的正常组织受照性。 附图说明 为了更清楚地说明本发明实施例或现有技术中的技术方案， 下面将对实施 例或现有技术描述中所需要使用的附图作筒单地介绍， 显而易见地， 下面描述 中的附图仅仅是本发明的一些实施例， 对于本领域普通技术人员来讲， 在不付 出创造性劳动的前提下， 还可以根据这些附图获得其他的附图。
图 1是现有的伽玛刀头部治疗有创定位装置；
图 2是现有的伽玛刀头部治疗装置中旋转治疗头的结构示意图； 图 3是本发明一实施例提供的伽玛刀头部治疗装置中旋转治疗头的结构示 意图；
图 4是本发明一实施例提供的伽玛刀头部治疗装置的结构框图。 具体实施方式
为了使本发明的目的、 技术方案及优点更加清楚明白， 以下结合附图及实 施例， 对本发明进行进一步详细说明。 应当理解， 此处所描述的具体实施例仅 仅用以解释本发明， 并不用于限定本发明。 请参见图 2 , 图 2是现有的伽玛刀头部治疗装置中旋转治疗头的结构示意 图。 如图 2所示， 现有的伽玛刀头部治疗装置中旋转治疗头包括： 钴源 120和 载源体 130。 其中， 钴源 120安装于载源体 130上， 其发出多束伽玛射线， 并 使它们几何聚焦以形成焦点 1 10。 在使用伽玛刀治疗装置前， 需要通过其他的 检查影像设备来确定病人头部肿瘤相对创定位装置的具体位置， 以根据病人头 部肿瘤的在创定位装置具体位置来对病人头部进行固定， 且这样一来就需要一 次性确定靶点及剂量， 不能够治疗需要分次治疗的病人。
图 3是本发明一实施例提供的伽玛刀头部治疗装置中旋转治疗头的结构示 意图。 如图 3所示， 本发明提供的伽玛刀头部治疗装置中旋转治疗头包括： 放 射源 220、 载源体 230、 锥形束 CT ( Cone Beam Computed Tomography, 以下筒 称为 CBCT )球管 240、 以及动态平板探测器 250。 放射源 220安装于载源体 230 上， 其发出多束伽玛射线， 并使它们几何聚焦以形成焦点 （即， 等中心） 210, 其中， 放射源 220可以为钴源， 载源体 230的形状可以是圆盘， 半球体， 或圆柱体等。 CBCT球管 240安装于载源体 230上，用于发射 X线，其中， CBCT 球管 240可以通过多种连接方式与载源体 230相连， 例如： 定位销及螺纹连接 方式。 动态平板探测器 250也安装于载源体 230上， 位于 CBCT球管 240的对 一侧， CBCT球管 240与动态平板探测器 250的垂直连接线通过焦点 210或与 焦点 210有已知固定尺寸位置， 也就是说， CBCT球管 240与动态平板探测器 250的垂直连接线与焦点 210的距离为固定尺寸， 例如： 50毫米、 100毫米、 300毫米、 或 500毫米等。 动态平板探测器 250用以采集 X线的投影数据， 以 便后续利用这些投影数据进行分析重建， 得到病人当前体位的头部三维立体数 据。 CBCT球管 240与动态平板探测器 250组成了 CBCT影像模块 310, CBCT 影像模块 310可绕病人头部在一个圆轨迹上做 360度旋转。
图 4是本发明一实施例提供的伽玛刀头部治疗装置的结构框图。 如图 4所 示， 本发明提供的伽玛刀头部治疗装置 300包括 CBCT影像模块 310、 三维数 据重建模块 320、 分析比对模块 330、 以及控制模块 340。 CBCT影像模块 310是由 CBCT球管 240与动态平板探测器 250组成， 其 连接于三维数据重建模块 320, 用以绕病人头部在一个圆轨迹上做 360度旋转， 以采集 X线的投影数据， 并将此投影数据传送到三维数据重建模块 320。 三维 数据重建模块 320, 连接于 CBCT影像模块 310以及分析比对模块 330, 用于 接收 CBCT影像模块 310传送的投影数据， 并根据此投影数据进行分析重建， 以得到病人当前体位的头部三维立体数据， 并将此头部三维立体数据发送到分 析比对模块 330。分析比对模块 330,连接于三维数据重建模块 320以及控制模 块 340, 用于接收三维数据重建模块 320发送的病人当前体位的头部三维立体 数据， 并将此头部三维立体数据与治疗计划使用的三维立体数据 （即， 先前通 过其他的检查设备来确定的病人头部肿瘤的具体位置）进行比对， 计算出所述 头部三维立体数据与治疗计划使用的三维立体数据的偏差值（即， 病人实际在 伽玛刀头部治疗装置 300中的位置与计划设计要求位置的偏差值） ， 并将此偏 差值发送到控制模块 340。 控制模块 340, 连接于分析比对模块 330, 用于接收 分析比对模块 330发送的偏差值， 若此偏差值小于系统预先设定的门限值时， 开始对病人进行治疗。 否则， 根据此偏差值进行病人实际位置修正， 并记录已 经修正的三维立体数据，并于位置修正后（即下发坐标尺寸变化后），控制 CBCT 影像模块 310在已修正的位置基础上采集新的投影数据。
另外， 本发明提供的伽玛刀头部治疗装置是使用头肩膜的无创定位方式对 病人头部进行固定， 减少了病人治疗过程中因为有创定位而产生的痛苦。
本发明以上实施例所提供的伽玛刀头部治疗装置及伽玛刀治疗系统， 通过 CBCT影像模块可以实现头部肿瘤的高精度定位， 同时可以实现头部肿瘤的小 剂量的分次治疗， 最大限度地保护病人的正常组织受照性。 另外， 由于病人是 通过头肩膜的无创定位方式进行固定， 减少了病人治疗过程中的痛苦， 且避免 了由过度环节导致的误差。 本领域技术人员应当知晓， 本发明所提供的伽玛刀 头部治疗装置及伽玛刀治疗系统也可用于治疗病人其他身体部位的肿瘤， 并不 限定于病人头部的治疗。 以上所述仅为本发明的较佳实施例而已， 并不用以限制本发明， 凡在本发 明的精神和原则之内所作的任何修改、 等同替换和改进等， 均应包含在本发明 的保护范围之内。

Claims

权 利 要 求 书
1、 一种伽玛刀头部治疗装置， 包括放射源及载源体， 所述放射源安装于所 述载源体上， 用以发出多束可几何聚焦并形成焦点的伽玛射线， 其特征在于， 所述伽玛刀头部治疗装置还包括 CBCT影像模块， 所述 CBCT影像模块包括 CBCT球管以及动态平板探测器， 其中：
所述 CBCT球管， 安装于所述载源体上； 以及
所述动态平板探测器， 安装于所述载源体上， 位于所述 CBCT球管的对一 侧， 其中，
所述 CBCT球管与所述动态平板探测器的垂直连接线通过所述焦点或与所 述焦点有已知固定尺寸位置。
2、 如权利要求 1所述的伽玛刀头部治疗装置， 其特征在于：
所述 CBCT球管， 用以发射 X线； 以及
所述动态平板探测器， 用以采集所述 X线的投影数据。
3、 如权利要求 1 所述的伽玛刀头部治疗装置， 其特征在于： 所述 CBCT 影像模块可绕病人头部在一个圆轨迹上做 360度旋转。
4、 如权利要求 1所述的伽玛刀头部治疗装置， 其特征在于： 所述放射源为 钴源。
5、 如权利要求 1所述的伽玛刀头部治疗装置， 其特征在于： 所述载源体的 形状可以是圆盘、 半球体、 或圆柱体。
6、 如权利要求 1 所述的伽玛刀头部治疗装置， 其特征在于： 所述 CBCT 球管是通过定位销及螺纹连接方式安装于所述载源体上。
7、 如权利要求 1所述的伽玛刀头部治疗装置， 其特征在于： 所述伽玛刀头 部治疗装置使用头肩膜对病人头部进行固定。
8、 如权利要求 2所述的伽玛刀头部治疗装置， 其特征在于， 还包括三维数 据重建模块、 分析比对模块、 以及控制模块， 其中：
所述三维数据重建模块， 连接于所述 CBCT影像模块以及所述， 用于接收 所述 CBCT影像模块传送的所述投影数据，并根据所述投影数据进行分析重建， 以得到病人当前体位的头部三维立体数据， 并将所述头部三维立体数据发送到 所述分析比对模块；
所述分析比对模块， 连接于所述三维数据重建模块以及所述控制模块， 用 于接收所述三维数据重建模块发送的所述头部三维立体数据， 并将所述头部三 维立体数据与治疗计划使用的三维立体数据进行比对， 计算出所述头部三维立 体数据与所述治疗计划使用的三维立体数据的偏差值， 并将所述偏差值发送到 所述控制模块； 以及
所述控制模块， 连接于所述分析比对模块， 用于接收所述分析比对模块发 送的所述偏差值， 若所述偏差值小于门限值时， 开始对病人进行治疗。
9、 如权利要求 8所述的伽玛刀头部治疗装置， 其特征在于： 若所述偏差值 大于所述门限值时， 所述控制模块根据所述偏差值对病人进行位置修正， 并记 录已经修正的三维立体数据， 并于位置修正后， 控制所述 CBCT影像模块在已 修正的位置基础上采集新的投影数据。
10、 一种伽玛刀治疗系统， 其特征在于， 包括如权利要求 1-9任一项所述 的伽玛刀头部治疗装置。
PCT/CN2013/072001 2013-02-28 2013-02-28 伽玛刀头部治疗装置及伽玛刀治疗系统 WO2014131179A1 (zh)

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